Constant-temperature vacuum Tibetan medicine fermentation and extraction system and equipment

Abstract

The invention relates to the technical field of medicine production, in particular to a constant-temperature vacuum Tibetan medicine fermentation and extraction system and equipment. The system comprises an area monitoring instrument accuracy verification platform, a fermentation time period instrument selection module and a medicine extraction state acquisition module. Accurate data corresponding to different types of accurate position point monitoring instruments are integrated through the medicine extraction state acquisition module, the current medicine constant-temperature vacuum fermentation state is judged, the corresponding accurate position point monitoring instruments in the same time period are integrated into an accurate position point monitoring instrument group, and various monitoring data in the group are acquired; the monitoring instrument with the most accurate monitoring data is selected for different time periods in the fermentation extraction process, the response efficiency of the monitoring data is improved, the monitoring error is reduced, meanwhile, the monitoring instrument is deployed and controlled according to accurate position points corresponding to all the time periods obtained through a monitoring data experiment, and the monitoring efficiency of the monitoring instrument is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of drug production, and specifically, to a constant-temperature vacuum Tibetan medicine fermentation extraction system and equipment. Background Art

[0002] Constant-temperature vacuum Tibetan medicine fermentation extraction is a traditional Chinese medicine extraction method that combines constant-temperature control, vacuum environment, and microbial fermentation technology. This technology aims to improve the extraction rate and purity of active ingredients in traditional Chinese medicine, while improving the quality and efficacy of traditional Chinese medicine. During this process, by controlling fermentation conditions such as temperature, pressure, and fermentation time, and using a vacuum environment to optimize the extraction process, target compounds can be more effectively extracted from traditional Chinese medicine.

[0003] During the fermentation extraction process, it is necessary to monitor the fermentation extraction status in real time through monitoring equipment, such as temperature monitoring instruments and pressure monitoring instruments. By using the above monitoring equipment, the drug fermentation extraction status can be obtained in real time as the basis for the fermentation extraction stage. The traditional monitoring method mainly fixes various monitoring instruments in the same position to obtain fermentation data in the current area, such as temperature and pressure. However, during the fermentation of drugs, the fermentation data will change at all times, and the amount of data change at different position points is also different. For example, during the fermentation process, it is necessary to inject gaseous reactants into the fermentation tank to accelerate the fermentation extraction speed of the drug. During this process, the pressure in the tank area near the nozzle will change greatly in a short time (compared with the normal state) until the gaseous reactants are evenly dispersed in the tank, and then the pressure in the tank will return to balance. If the pressure monitoring instrument does not obtain the pressure deviation caused by injecting gaseous reactants in the first time at the current stage, it will cause the experimenter to not be able to obtain whether the injected gaseous reactants meet the standards in the first time. Therefore, the monitoring instruments at a single fixed position cannot adapt to the monitoring work at different time periods. To solve this problem, it is necessary to set up monitoring instruments at multiple position points for multi-point data monitoring. However, different drug fermentation extraction methods are different, and the corresponding fermentation data are also different. Therefore, not only it is necessary to set up monitoring instruments at multiple position points, but also it is necessary to determine the position points with the most accurate monitoring data under different time point states, and arrange the monitoring instruments through these position points, resulting in a greatly reduced monitoring effect of the monitoring instruments.

[0004] To address the above problems, there is an urgent need for a constant-temperature vacuum Tibetan medicine fermentation extraction system and equipment. Summary of the Invention

[0005] The purpose of the present invention is to provide a constant-temperature vacuum Tibetan medicine fermentation extraction system and equipment to solve the problems raised in the above background art.

[0006] To achieve the above object, one of the objects of the present invention is to provide a constant-temperature vacuum medicine fermentation extraction system, including an accuracy verification platform for regional monitoring instruments, a fermentation time period instrument selection module, and a medicine extraction state acquisition module;

[0007] The accuracy verification platform for regional monitoring instruments is used to obtain the monitoring accuracy of fermentation data of monitoring instruments at different positions in the fermentation tank at different time periods;

[0008] The accuracy verification platform for regional monitoring instruments includes a monitoring instrument position point division unit, a monitoring time period division unit, a fermentation data deviation range acquisition unit, and a monitoring instrument weight division unit;

[0009] Among them, the monitoring instrument position point division unit is used to plan the positions of different monitoring instruments in the fermentation tank, including the layout of the same monitoring instrument at different positions;

[0010] The monitoring time period division unit is used to divide different monitoring time periods during the fermentation process and obtain the monitoring data fed back by each monitoring instrument at different time periods;

[0011] The fermentation data deviation range acquisition unit combines the fed-back monitoring data to obtain the data deviation range of the monitoring instruments at the same position point in different experimental groups;

[0012] The monitoring instrument weight division unit combines the data deviation range to establish a weight distribution model and allocate the monitoring weights of the monitoring instruments at different position points in different time periods;

[0013] The fermentation time period instrument selection module combines the monitoring weights of the monitoring instruments at different time periods to determine the monitoring instruments at the accurate position points, and takes the monitoring data of the monitoring instruments at the accurate position points corresponding to the time periods as accurate data;

[0014] The medicine extraction state acquisition module is used to integrate the accurate data corresponding to different types of monitoring instruments at the accurate position points and determine the current constant-temperature vacuum fermentation state of the medicine.

[0015] As a further improvement of this technical solution, the monitoring instruments in the accuracy verification platform for regional monitoring instruments include several pressure sensors, several temperature sensors, and several pH value measuring instruments;

[0016] Among them, the pressure sensor is used to collect the pressure change value in the fermentation tank;

[0017] The temperature sensor is used to collect the temperature change value in the fermentation tank;

[0018] The pH value measuring instrument is used to monitor the pH change value of the fermentation broth.

[0019] As a further improvement of this technical solution, the method for the monitoring instrument position point division unit to plan the positions of different monitoring instruments in the fermentation tank includes the following steps:

[0020] S1. Obtain the monitoring status of different types of monitoring instruments and determine the corresponding monitoring area Mon area ;

[0021] S2. Establish the monitoring data difference Md difference , and obtain the monitoring data values Mon values monitored at adjacent monitoring position points;

[0022] When Mon values ≥ Md difference , obtain the distance between adjacent monitoring position points and mark it as the monitoring unit distance Mon distance ;

[0023] S3. According to the monitoring unit distance Mon distance corresponding to each monitoring instrument, divide the monitoring position points corresponding to the monitoring area Mon area and deploy monitoring instruments.

[0024] As a further improvement of this technical solution, the method for the fermentation data deviation range acquisition unit to obtain the data deviation range of the monitoring instruments at the same position points of different experimental groups includes the following steps:

[0025] S10. Adopt the monitoring time periods divided by the monitoring time period division unit, and obtain the monitoring data values Mon values corresponding to the monitoring instruments at the monitoring position points of different experimental groups at intervals of the monitoring time periods;

[0026] S20. Summarize the monitoring data values Mon values at the same monitoring position points in the same monitoring time period of different time groups to generate a set of position point data values

[0027] S30. Select the minimum monitoring data value and the maximum monitoring data value

[0028] S40. Calculate the data deviation range

[0029] As a further improvement of this technical solution, the method for the monitoring instrument weight division unit to establish a weight distribution model includes the following steps:

[0030] S100. Obtain the deployment quantity of different monitoring instruments in the fermentation tank and establish a weight distribution set Wall set = {w1, w2,..., wn}, where w1 to w n are weight values, arranged from largest to smallest, and n corresponds to the deployment quantity of monitoring instruments;

[0031] S200. Combine the data deviation ranges De corresponding to different monitoring position points of the same type of monitoring instruments obtained by different experimental groups calculated in combination with the above S40 within the same time period value ;

[0032] S300. Establish a data deviation range set in ascending order where to are the data deviation ranges corresponding to the same monitoring instrument at different monitoring position points, and are arranged from smallest to largest;

[0033] S400. Combine the data deviation range set D and the weight allocation set Wall set , and match the corresponding weight sizes of the data deviation range De value in the order of the set.

[0034] As a further improvement of this technical solution, the accurate data in the fermentation time period instrument selection module includes the accurate data fed back by the pressure sensor, the accurate data fed back by the temperature sensor, and the accurate data fed back by the PH value measuring instrument.

[0035] As a further improvement of this technical solution, the drug extraction state acquisition module includes a standard value storage unit, a feedback value matching and comparison unit, and a comparison result analysis unit;

[0036] Among them, the standard value storage unit is used to store the standard values St of the accurate data corresponding to different time periods value and the deviation threshold De threshold ;

[0037] The feedback value matching and comparison unit is used to obtain the accurate data fed back by the monitoring instrument in real time;

[0038] The result analysis unit compares the accurate data fed back by the monitoring instrument with the corresponding standard value to obtain the deviation value D threshold , when the three deviation values D threshold ≤De threshold , it indicates that the fermentation and extraction state data is normal at this time. When one or more of the three deviation values D threshold >De threshold , it indicates that the fermentation and extraction state data is abnormal at this time.

[0039] The second object of the present invention is to provide a device for realizing a constant-temperature vacuum Tibetan medicine fermentation extraction system, including a fermentation tank, an air inlet pipe for providing reaction gas, and a stirring shaft for performing fermentation stirring treatment. Each of the pressure sensors is arranged at the port position of the air inlet pipe to monitor the pressure change at the inner end of the fermentation tank in real time. Each of the temperature sensors is arranged inside the fermentation tank to monitor the temperature change at the inner end of the fermentation tank in real time. Each of the pH value measuring instruments is arranged at the inner bottom end position to monitor the acidity and alkalinity inside the fermentation broth.

[0040] Compared with the prior art, the beneficial effects of the present invention are:

[0041] In the constant-temperature vacuum Tibetan medicine fermentation extraction system and device, through the drug extraction state acquisition module, the accurate data corresponding to different types of precise position point monitoring instruments are integrated to determine the current constant-temperature vacuum fermentation state of the drug. The precise position point monitoring instruments corresponding to each precise position point within the same time period are integrated into a precise position point monitoring instrument group, and various monitoring data within the group are obtained. The monitoring instrument with the most accurate monitoring data is selected for different time periods during the fermentation extraction process, improving the monitoring data response efficiency and reducing monitoring errors. At the same time, according to the precise position points corresponding to each time period obtained through monitoring data experiments, the monitoring instruments are arranged according to the precise position points, improving the monitoring efficiency of the monitoring instruments. BRIEF DESCRIPTION OF THE DRAWINGS

[0042] Figure 1 is the overall system flow block diagram of the present invention;

[0043] Figure 2 is the flow block diagram of the drug extraction state acquisition module of the present invention;

[0044] Figure 3 is the overall device structure schematic diagram of the present invention.

[0045] The meanings of each label in the figure are as follows:

[0046] 1, fermentation tank; 11, air inlet pipe; 12, stirring shaft;

[0047] 2, pressure sensor;

[0048] 3, temperature sensor;

[0049] 4, pH value measuring instrument;

[0050] 10, regional monitoring instrument accuracy verification platform; 110, monitoring instrument position point division unit; 120, monitoring time period division unit; 130, fermentation data deviation range acquisition unit; 140, monitoring instrument weight division unit;

[0051] 20, fermentation time period instrument selection module;

[0052] 30. Drug extraction status acquisition module; 310. Standard value storage unit; 320. Feedback value matching and comparison unit; 330. Comparison result analysis unit. Detailed implementation mode

[0053] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present invention without creative efforts shall fall within the protection scope of the present invention.

[0054] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present invention.

[0055] Please refer to Figure 1 As shown, one of the purposes of the present invention is to provide a constant temperature vacuum medicine fermentation extraction system, including a regional monitoring instrument accuracy verification platform 10, a fermentation time period instrument selection module 20, and a drug extraction status acquisition module 30;

[0056] The regional monitoring instrument accuracy verification platform 10 is used to obtain the fermentation data monitoring accuracy of the monitoring instruments at different positions of the fermentation tank at different time periods;

[0057] The regional monitoring instrument accuracy verification platform 10 includes a monitoring instrument position point division unit 110, a monitoring time period division unit 120, a fermentation data deviation range acquisition unit 130, and a monitoring instrument weight division unit 140;

[0058] Among them, the monitoring instrument position point division unit 110 is used to plan the positions of different monitoring instruments in the fermentation tank, including the layout of the same monitoring instrument at different positions;

[0059] The monitoring time period division unit 120 is used to divide different monitoring time periods during the fermentation process and obtain the monitoring data fed back by each monitoring instrument in different time periods;

[0060] The fermentation data deviation range acquisition unit 130 combines the fed-back monitoring data to obtain the data deviation range of the monitoring instruments at the same position point in different experimental groups;

[0061] The monitoring instrument weight division unit 140 combines the data deviation range to establish a weight distribution model and assigns the monitoring weights of the monitoring instruments at different positions in different time periods.

[0062] The fermentation time period instrument selection module 20 determines the monitoring instruments at the precise position points by combining the monitoring weights of the monitoring instruments in different time periods, and uses the monitoring data corresponding to the time periods of the monitoring instruments at the precise position points as the precise data.

[0063] The drug extraction state acquisition module 30 is used to integrate the precise data corresponding to different types of monitoring instruments at the precise position points to determine the current state of the drug's constant temperature vacuum fermentation.

[0064] During specific use, during the process of the constant temperature vacuum drug fermentation extraction experiment, the fermentation data monitoring accuracy of the monitoring instruments at different positions of the fermentation tank in different time periods is obtained through the regional monitoring instrument accuracy verification platform 10. The specific method is as follows:

[0065] First, the monitoring instrument position point division unit 110 plans the positions of different monitoring instruments in the fermentation tank, including the layout of the same monitoring instrument at different positions. That is, according to the monitoring method of the monitoring instrument, the monitoring instrument is arranged at different position points in the tank body. For the same monitoring instrument, an interval distance is set to establish an experimental group, that is, the added raw materials are the same, the temperature in the tank is the same, the stirring method, the amount of reactants introduced, etc. These parameters are kept consistent.

[0066] After completing the layout of the monitoring instruments, the monitoring time period division unit 120 divides different monitoring time periods during the fermentation process, that is, combines the fermentation extraction methods of different drugs to obtain the time periods when their fermentation data changes. For example, when gas needs to be introduced in a certain stage, the corresponding pressure will change, and even the temperature will change slightly. At this time, the stage of passing gas is used as one of the time periods, and then the monitoring data feedback by each monitoring instrument in different time periods is obtained.

[0067] During the experiment, the fermentation data deviation range acquisition unit 130 combines the feedback monitoring data to obtain the data deviation range of the monitoring instruments at the same position points in different experimental groups, that is, within the same time period, the monitoring data deviations of the monitoring instruments at the same position points in different experimental groups are obtained. Subsequently, the monitoring instrument weight division unit 140 combines the data deviation range to establish a weight distribution model and assigns the monitoring weights of the monitoring instruments at different positions in different time periods. The deviation range is inversely proportional to the monitoring weight.

[0068] After completing the monitoring weight division work, at this time, the precise position point monitoring instrument is determined through the fermentation time period instrument selection module 20, and the monitoring data corresponding to the precise position point monitoring instrument in the corresponding time period is used as the precise data, that is, the monitoring instrument that can monitor the accurate data corresponding to the current fermentation and extraction state at different time periods is determined, and this monitoring instrument is marked as the precise position point monitoring instrument, and its location is marked as the precise position point. At this time, the data obtained by the precise position point monitoring instrument is used as the most accurate monitoring data in this time period;

[0069] Finally, the drug extraction state acquisition module 30 integrates the precise data corresponding to different types of precise position point monitoring instruments to determine the current drug constant temperature and vacuum fermentation state. Because there are multiple types of fermentation data to be monitored and there are also multiple corresponding precise position point monitoring instruments, the precise position point monitoring instruments corresponding to the same time period are integrated into a precise position point monitoring instrument group, and various monitoring data within the group are obtained. The monitoring instrument with the most accurate monitoring data is selected for different time periods during the fermentation and extraction process to improve the response efficiency of the monitoring data and reduce the monitoring error. At the same time, according to the precise position points corresponding to each time period obtained through the monitoring data experiment, the monitoring instruments are arranged according to the precise position points to improve the monitoring efficiency of the monitoring instruments.

[0070] In addition, the monitoring instruments in the regional monitoring instrument accuracy verification platform 10 include several pressure sensors 2, several temperature sensors 3, and several pH value measuring instruments 4;

[0071] Among them, the pressure sensor 2 is used to collect the pressure change value in the fermentation tank;

[0072] The temperature sensor 3 is used to collect the temperature change value in the fermentation tank;

[0073] The pH value measuring instrument 4 is used to monitor the pH change value of the fermentation broth.

[0074] It should be noted that since the monitoring methods of different monitoring instruments are different, for example, the pressure sensor 2 needs to be arranged near the intake pipeline, and the pH value measuring instrument 4 needs to be in contact with the liquid in the tank to conduct monitoring, so its layout area needs to be close to the liquid level.

[0075] Furthermore, the method for the monitoring instrument position point division unit 110 to plan the positions of different monitoring instruments in the fermentation tank includes the following steps:

[0076] S1. Obtain the monitoring status of different types of monitoring instruments and determine the corresponding monitoring area Mon area ;

[0077] S2. Establish the monitoring data difference Md difference , and obtain the monitoring data values Mon values ;

[0078] When Mon values ≥MD difference At this time, obtain the distance between adjacent monitoring position points, and mark it as the monitoring unit distance Mon distance ;

[0079] S3. According to the monitoring unit distance Mon corresponding to each monitoring instrument distance , divide the monitoring position points corresponding to the monitoring area Mon area , and deploy monitoring instruments.

[0080] In specific use, during the deployment process of monitoring instruments, since the monitoring methods of different monitoring instruments are different, the corresponding monitoring areas will also change. Therefore, during specific deployment, it is first necessary to obtain the monitoring status of different types of monitoring instruments and determine the corresponding monitoring area Mon area , for example, a pressure sensor needs to be deployed near the intake pipeline. However, if the distance between adjacent monitoring instruments is too close, it will result in no difference in their monitoring data, making the monitoring data meaningless. To avoid this problem, it is necessary to establish a monitoring data difference Md difference , obtain the monitoring data values Mom of adjacent monitoring position points values ;

[0081] When Mon values ≥Md difference At this time, obtain the distance between adjacent monitoring position points, and mark it as the monitoring unit distance Mon distance , that is, during the subsequent deployment process, in the corresponding monitoring area Mon area According to the monitoring unit distance Mon distance , locate each monitoring position point, install the monitoring instrument, ensure the comprehensiveness of the monitoring data, and improve the monitoring effect.

[0082] Furthermore, the method for obtaining the data deviation range of the monitoring instruments at the same position points in different experimental groups in the fermentation data deviation range obtaining unit 130 includes the following steps:

[0083] S10. Adopt the monitoring time period divided by the monitoring time period dividing unit 120, and obtain the monitoring data values Mon corresponding to the monitoring instruments at the monitoring position points of different experimental groups at intervals of the monitoring time period values ;

[0084] S20. Summarize the monitoring data values Mon at the same monitoring position points in the same monitoring time period of different time groups values , and generate a set of position point data values

[0085] S30. Select the minimum monitoring data value in the set M of position point data values and the maximum monitored data value

[0086] S40. Calculate the data deviation range

[0087] Specifically, the method for establishing the weight distribution model in the monitoring instrument weight division unit 140 includes the following steps:

[0088] S100. Obtain the deployment quantity of different monitoring instruments in the fermenter and establish a weight distribution set Wall set ={w1, w2,..., w n}, where w1 to w n are the weight quantities and are arranged from large to small, and n corresponds to the deployment quantity of the monitoring instruments;

[0089] S200. Combine the data deviation ranges De corresponding to different monitoring position points of the same type of monitoring instrument obtained by different experimental groups in the same time period calculated in S40 value ;

[0090] S300. Establish a data deviation range set in ascending order where to are the data deviation ranges corresponding to the same monitoring instrument at different monitoring position points and are arranged from small to large;

[0091] S400. Combine the data deviation range set D and the weight distribution set Wall set , and match the corresponding weight sizes of the data deviation range De value in the order of the sets.

[0092] In specific use, during the weight distribution process, since the data deviation ranges De of the monitoring data monitored by the monitoring instruments deployed at different monitoring position points in the fermenter value are different, the corresponding data fluctuations will also be different. The greater the data fluctuation, the less accurate the monitored data. At this time, it is necessary to use the monitoring time period divided by the monitoring time period division unit 120 to obtain the monitored data values Mon values corresponding to the monitoring instruments at the monitoring position points of different experimental groups at intervals of the monitoring time period, and then summarize the monitored data values Mon values at the same monitoring position points in the same monitoring time period of different time groups to generate a position point data value set For example, if there are 5 pressure sensors deployed in the fermenter, that is, it indicates m = 5, respectively {Y 11 ; Y 12 ; Y 13 ; Y 14 ; Y 15}, representing the monitoring values of Area I, Area II, Area III, Area IV, and Area V. A total of 4 groups are set up, and corresponding pressure sensors are arranged at the same positions in each group. The other 3 groups are respectively {Y 21 ; Y 22 ; Y 23 ; Y 24 ; Y 25}, {Y 31 ; Y 32 ; Y 33 ; Y 34 ; Y 35}, and {Y 41 ; Y 42 ; Y 43 ; Y 44 ; Y 45}. In order to determine the monitoring accuracy of the pressure sensors at different position points, it is necessary to select the minimum monitoring data value and the maximum monitoring data value in the position point data value set M. That is, in the example, Y 11 , Y 21 , Y 31 , and Y 41 are the monitoring data values Mon values obtained by the pressure sensors at the same position points in different experimental groups. Obtain the maximum and minimum values among them. For example, Y 21 is the minimum monitoring data value Y 41 is the maximum monitoring data value At this time, the data deviation range De value = Y 41 - Y 21 . According to the above calculation method, calculate the data deviation ranges De value of Area II, Area III, Area IV, and Area V in turn, and obtain the data deviation range set

[0093] by sorting according to size. When performing weight distribution, it is necessary to obtain the layout quantity of different monitoring instruments in the fermenter and establish a weight distribution set Wall set = {w1, w2,..., w n}, where w1 to w n are the weight values and are arranged from large to small. n corresponds to the layout quantity of the monitoring instruments. From the above example, at this time n = 5. It should be noted that the size of the weight value can be any value, but the size order is constant. Finally, combine the data deviation range set D and the weight distribution set Wall set , and match the weight size corresponding to the data deviation range De value according to the set order, that is, w1 corresponds to And represents the minimum data deviation range De in the current time period value , as a reference for determining the precise position point monitoring instrument corresponding to different time periods later

[0094] In addition, the precise data in the fermentation time period instrument selection module 20 includes the precise data fed back by the pressure sensor, the precise data fed back by the temperature sensor, and the precise data fed back by the PH value measuring instrument. Since in the actual monitoring process, in order to determine the fermentation and extraction state, it is necessary to determine through multiple data feedbacks. First, it is necessary to determine the precise position point monitoring instrument within the same time period, that is, the precise position point pressure sensor, the precise position point temperature sensor, and the precise position point PH value measuring instrument, and obtain the precise data of different monitoring instruments as the numerical standard for judging the fermentation and extraction state.

[0095] Furthermore, as Figure 2 shown, the drug extraction state acquisition module 30 includes a standard value storage unit 310, a feedback value matching and comparison unit 320, and a comparison result analysis unit 330;

[0096] Among them, the standard value storage unit 310 is used to store the standard values St of the precise data corresponding to different time periods value and the deviation threshold De threshold ;

[0097] The feedback value matching and comparison unit 320 is used to obtain the precise data fed back by the monitoring instrument in real time;

[0098] The result analysis unit 330 compares the precise data fed back by the monitoring instrument with the corresponding standard value to obtain the deviation value D threshold , when the three deviation values D threshold ≤De threshold , it indicates that the fermentation and extraction state data is normal at this time. When one or more of the three deviation values D threshold >De threshold , it indicates that the fermentation and extraction state data is abnormal at this time.

[0099] The second object of the present invention is to provide a device for realizing a constant temperature vacuum medicine storage fermentation and extraction system, as Figure 3As shown in the figure, it includes a fermentation tank 1, an inlet pipe 11 for supplying reaction gas, and a stirring shaft 12 for performing fermentation stirring treatment. Each pressure sensor 2 is arranged at the port position of the inlet pipe 11 to monitor the pressure change at the inner end of the fermentation tank 1 in real time. Each temperature sensor 3 is arranged inside the fermentation tank 1 to monitor the temperature change at the inner end of the fermentation tank 1 in real time. Each pH value measuring instrument 4 is arranged at the inner bottom end position to monitor the acidity and alkalinity inside the fermentation broth. During specific use, in the process of monitoring, the precise position point monitoring instruments corresponding to different time periods are determined in advance through experiments. During actual fermentation and extraction, when the corresponding time point is reached, through the corresponding precise position point monitoring instruments, that is, the precise data fed back by the pressure sensor, the precise data fed back by the temperature sensor, and the precise data fed back by the pH value measuring instrument, the fermentation and extraction state is determined through the precise data provided by the three monitoring instruments.

[0100] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art of this industry should understand that the present invention is not limited by the above embodiments. The above embodiments and the descriptions in the specification are only preferred examples of the present invention and are not used to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed. The scope of protection claimed by the present invention is defined by the appended claims and their equivalents.

Claims

1. A constant-temperature vacuum medicine storage fermentation extraction system, characterized in that: It includes a regional monitoring instrument accuracy verification platform (10), a fermentation time period instrument selection module (20), and a drug extraction status acquisition module (30); The regional monitoring instrument accuracy verification platform (10) is used to obtain the monitoring accuracy of fermentation data of monitoring instruments at different positions of the fermenter at different time periods; The regional monitoring instrument accuracy verification platform (10) includes a monitoring instrument position point division unit (110), a monitoring time period division unit (120), a fermentation data deviation range acquisition unit (130), and a monitoring instrument weight division unit (140); Among them, the monitoring instrument position point division unit (110) is used to plan the positions of different monitoring instruments in the fermenter, including the layout of the same monitoring instrument at different positions; The monitoring time period division unit (120) is used to divide different monitoring time periods during the fermentation process and obtain the monitoring data fed back by each monitoring instrument in different time periods; The fermentation data deviation range acquisition unit (130) combines the fed-back monitoring data to obtain the data deviation range of the monitoring instruments at the same position point in different experimental groups; The monitoring instrument weight division unit (140) combines the data deviation range to establish a weight distribution model and assigns monitoring weights to the monitoring instruments at different position points in different time periods; The fermentation time period instrument selection module (20) combines the monitoring weights of the monitoring instruments in different time periods to determine the monitoring instruments at the accurate position points, and takes the monitoring data corresponding to the accurate position point monitoring instruments in the corresponding time period as accurate data; The drug extraction status acquisition module (30) is used to integrate the accurate data corresponding to different types of accurate position point monitoring instruments and determine the current drug constant temperature vacuum fermentation status.

2. The constant-temperature vacuum medicine storage fermentation extraction system according to claim 1, wherein: The monitoring instruments in the regional monitoring instrument accuracy verification platform (10) include a number of pressure sensors (2), a number of temperature sensors (3), and a number of pH value measuring instruments (4); Among them, the pressure sensor (2) is used to collect the pressure change values in the fermenter; The temperature sensor (3) is used to collect the temperature change values in the fermenter; The pH value measuring instrument (4) is used to monitor the pH value change values of the fermentation broth.

3. The constant-temperature vacuum medicinal fermentation and extraction system according to claim 1, wherein: The method for the monitoring instrument position point division unit (110) to plan the positions of different monitoring instruments in the fermenter includes the following steps: S1. Obtain the monitoring status of different types of monitoring instruments and determine the corresponding monitoring area Mon area ; S2. Establish the monitoring data difference Md difference , and obtain the monitoring data value Mon monitored at adjacent monitoring position points values ; When Mon values ≥ Md difference obtain the distance between adjacent monitoring position points, marked as the monitoring unit distance Mon distance ; S3. Divide the monitoring area Mon according to the monitoring unit distance Mon corresponding to each monitoring instrument distance , and define the corresponding monitoring position points of the monitoring area Mon area , and deploy monitoring instruments 4. The constant-temperature vacuum medicine storage fermentation extraction system according to claim 1, wherein: The method for the fermentation data deviation range acquisition unit (130) to obtain the data deviation range of the monitoring instruments at the same position point in different experimental groups includes the following steps: S10. During the monitoring time periods divided by the monitoring time period division unit (120), obtain the monitoring data value Mon corresponding to the monitoring instruments at the monitoring position points of different experimental groups at intervals of the monitoring time periods valus ; S20. Aggregate the monitoring data values Mon at the same monitoring location points in the same monitoring time period for different time groups value , and generate a set of data values for the location points S30. Select the minimum monitored data value from the set M of position point data values and the maximum monitored data value S40. Calculate the data deviation range 5. The constant-temperature vacuum medicinal fermentation and extraction system according to claim 1, wherein: The method for the monitoring instrument weight division unit (140) to establish a weight distribution model includes the following steps: S100. Obtain the layout quantities of different monitoring instruments in the fermenter and establish a weight distribution set Wall set ={w1, w2,..., w n}, where w1 to w n are weight quantities, arranged from largest to smallest, and n corresponds to the layout quantity of the monitoring instrument; S200. Calculate the data deviation range De corresponding to different monitoring position points of the same type of monitoring instrument obtained by different experimental groups within the same time period in combination with the S40 calculated above value ; S300. Establish a data deviation range set sorted by size wherein to are the data deviation ranges corresponding to the same monitoring instrument at different monitoring position points, and are arranged from small to large; S400, combined with the data deviation range set D and the weight assignment set Wall set , match the data deviation range De in the order of the set value corresponding weight size.

6. The constant-temperature vacuum medicine storage fermentation extraction system according to claim 1, wherein: The accurate data in the fermentation time period instrument selection module (20) includes the accurate data fed back by the pressure sensor, the accurate data fed back by the temperature sensor, and the accurate data fed back by the pH value measuring instrument.

7. The constant-temperature vacuum medicine storage fermentation extraction system according to claim 1, characterized in that: The drug extraction status acquisition module (30) includes a standard value storage unit (310), a feedback value matching and comparison unit (320), and a comparison result analysis unit (330); Among them, the standard value storage unit (310) is used to store the standard value St of each precise data corresponding to different time periods value and the deviation threshold De threshold ; The feedback value matching and comparison unit (320) is used to obtain the accurate data fed back by the monitoring instrument in real time; The result analysis unit (330) compares the accurate data fed back by the monitoring instrument with the corresponding standard value to obtain the deviation value D threshold , when the three deviation values D threshold ≤De threshold , it indicates that the fermentation extraction state data is normal at this time. When one or more of the three deviation values D threshold >De threshold , it indicates that the fermentation extraction state data is abnormal at this time.

8. An apparatus for implementing the constant-temperature vacuum medicine storage fermentation extraction system according to claim 2, characterized in that: It includes a fermentation tank (1), an air inlet pipe (11) for supplying reaction gas, and a stirring shaft (12) for performing fermentation stirring treatment. Each of the pressure sensors (2) is arranged at the port position of the air inlet pipe (11) to monitor the pressure change at the inner end of the fermentation tank (1) in real time. Each of the temperature sensors (3) is arranged inside the fermentation tank (1) to monitor the temperature change at the inner end of the fermentation tank (1) in real time. Each of the pH value measuring instruments (4) is arranged at the inner bottom end position to monitor the acidity and alkalinity inside the fermentation broth.

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