An automatically adjustable brain stereotaxic apparatus

Abstract

This invention discloses an automatically adjustable stereotaxic brain localization device, relating to the field of automatic control. It includes a brain localization component, an adjustment frame with its lower end mounted on a base, an X-axis adjustment component mounted on the upper end of the adjustment frame, a Y-axis adjustment component mounted on the X-axis adjustment component, a dual-angle adjustment component mounted on the Y-axis adjustment component, a Z-axis adjustment component mounted on the dual-angle adjustment component, a tool clamping component mounted on the Z-axis adjustment component, and the brain localization component mounted on the base. The X, Y, and Z-axis adjustment components are all electrically connected to a control center. The tool clamping component is sequentially mounted on the adjustment frame via the Z-axis adjustment component, the dual-angle adjustment component, the Y-axis adjustment component, and the X-axis adjustment component. The adjustment frame is very stable on the base, enabling precise positioning. Simultaneously, the Z, Y, and X-axis adjustment components are automatically adjusted by the control center.

Description

Technical Field

[0001] This invention relates to the field of automatic control, and in particular to an automatically adjustable stereotaxic device. Background Technology

[0002] Animal stereotaxic positioning systems are crucial research tools that use a three-dimensional coordinate system to precisely locate specific brain regions, enabling targeted interventions such as electrode implantation and drug injection, as well as recording neural signals. They also deliver drugs or transplanted cells with millimeter-level precision, providing spatial positioning support for neuromodulation research and the construction of brain disease treatment models. Currently, most existing stereotaxic positioning systems are designed with cantilever beam structures. However, the relatively weak stability of cantilever structures leads to lower positioning accuracy. Some systems require manual adjustment by the operator, which is slow and inconvenient. Summary of the Invention

[0003] The purpose of this invention is to overcome the shortcomings of the prior art and provide an automatically adjustable stereotaxic device.

[0004] The objective of this invention is achieved through the following technical solution:

[0005] An automatically adjustable stereotaxic brain localization device includes a base, an adjustment frame, an X-axis adjustment component, a Y-axis adjustment component, a Z-axis adjustment component, a dual-angle adjustment component, a brain localization component, and a tool clamping component. The lower end of the adjustment frame is disposed on the base, the X-axis adjustment component is disposed on the upper end of the adjustment frame, the Y-axis adjustment component is disposed on the output part of the X-axis adjustment component, the dual-angle adjustment component is disposed on the output part of the Y-axis adjustment component, the Z-axis adjustment component is disposed on the output part of the dual-angle adjustment component, the tool clamping component is disposed on the output part of the Z-axis adjustment component, and the brain localization component is disposed on the base and cooperates with the tool clamping component. The X-axis adjustment component, the Y-axis adjustment component, and the Z-axis adjustment component are all electrically connected to a control center.

[0006] Furthermore, the X-axis adjustment assembly includes an X-axis motor, an X-axis slider, an X-axis guide rail, an X-axis lead screw, an X-axis scale, and an X-axis mark. The X-axis guide rail is fixedly mounted on the top of the adjustment frame, the X-axis slider is slidably mounted on the X-axis guide rail, the X-axis motor is fixedly mounted on the adjustment frame, the X-axis lead screw is mounted on the output shaft of the X-axis motor and threadedly engaged with the X-axis slider, the X-axis scale is mounted on the top of the adjustment frame, and the X-axis mark is mounted on the X-axis slider to engage with the X-axis scale.

[0007] Furthermore, the Y-axis adjustment assembly includes a Y-axis motor, a Y-axis guide rod, a Y-axis lead screw, a Y-axis output block, a Y-axis fixed block, and a Y-axis scale. The Y-axis motor is fixedly mounted on the Y-axis fixed block. The Y-axis guide rod passes through the X-axis slider and is fixedly connected to the Y-axis output block. The two ends of the Y-axis scale are respectively mounted on the Y-axis output block and the Y-axis fixed block. The Y-axis lead screw is mounted on the output part of the Y-axis motor and is threadedly engaged with the X-axis slider.

[0008] Further, the dual-angle adjustment assembly includes a first rotating block, a second rotating block, a first rotating scale, a second rotating scale, a first locking screw, a second locking screw, a limiting block, a central rotating shaft, and a rotating shaft locking head. The Y-axis output block has a rotating hole, and one end of the first rotating block is rotatably disposed within the rotating hole. The Y-axis output block and the first rotating block are fixedly connected by the first locking screw. The limiting block is fixedly disposed on the Y-axis output block. The first rotating block has a limiting groove that mates with the limiting block. The other end of the first rotating block has a rotating groove. One end of the second rotating block is rotatably disposed in the rotating groove via the central rotating shaft. The central rotating shaft is fixed to the first rotating block by the rotating shaft locking head. The second rotating block is fixed to the first rotating block by the second locking screw. The first rotating block has a first rotating scale, the Y-axis output block has a first rotating mark that mates with the first rotating scale, the second rotating block has a second rotating scale, and the first rotating block has a second rotating mark that mates with the second rotating scale.

[0009] Furthermore, the Z-axis adjustment assembly includes a Z-axis motor, a Z-axis guide rod, a Z-axis lead screw, a Z-axis output block, and a Z-axis scale. The Z-axis guide rod is slidably mounted on the second rotating block, the Z-axis output block is fixedly mounted on the lower end of the Z-axis guide rod, the Z-axis motor is fixedly mounted on the upper end of the Z-axis guide rod, the Z-axis lead screw is mounted on the output part of the Z-axis motor and threadedly engaged with the second rotating block, and the Z-axis scale is mounted on the outer wall of the Z-axis guide rod.

[0010] Furthermore, the tool clamping assembly includes a connecting block, a locking sleeve, a top block, a sliding pin, an ejection spring, an ejection knob, and a tool clamping component. The locking sleeve has a through-hole locking groove. The top block is slidably disposed within the locking groove and engages with it. The sliding pin is fixedly disposed on both sides of the top block. The locking sleeve has pin grooves on both sides that engage with the sliding pins. A first clamping groove is disposed at one end of the top block. A second clamping groove is disposed on the inner wall of the locking groove that engages with the first clamping groove. The tool clamping component is disposed between the first and second clamping grooves. The ejection spring is disposed between the other end of the top block and the inner wall of the locking sleeve. The ejection spring is sleeved on the ejection knob. The ejection knob is threadedly engaged with the locking sleeve. The top block is fixed to the Z-axis output block via the connecting block.

[0011] Furthermore, the tool clamping component includes a tool end, a tool ring, a tool knob, and a connecting rod. The upper end of the connecting rod is disposed between the first clamping groove and the second clamping groove. The tool end is disposed on the lower end of the connecting rod. The tool knob fixes the tool ring to the outer wall of the tool end. A tool groove is provided on the outer wall of the tool end.

[0012] Furthermore, the brain positioning component includes a sliding plate, a sliding strip, a locking strip, a cam handle, a locking lug component, and a locking nose component. A limiting groove is provided on the upper surface of the base. The sliding strip is slidably disposed in the limiting groove and cooperates with the limiting groove. The sliding strip is fixedly connected to the sliding plate. A locking groove is provided on the base to cooperate with the limiting groove. The locking strip is disposed in the locking groove and cooperates with the sliding strip on one side. The other side of the locking strip cooperates with the cam handle on the base.

[0013] Furthermore, the locking lug component includes a locking lug seat, a lug rod, a lug sleeve, an inner spring, a spring plug, a clamping plate, and a clamping knob. The locking lug seat is fixedly mounted on the sliding plate, the lug sleeve is fixedly mounted on the upper end of the locking lug seat, the spring plug is mounted on one end of the lug sleeve, the inner spring is mounted inside the lug sleeve and one end engages with the spring plug, the lug rod is mounted inside the other end of the lug sleeve and engages with the other end of the inner spring, the locking lug seat is provided with a clamping plate for fixing the lug rod, and the locking lug seat is fixed to the locking lug seat by the clamping knob.

[0014] Furthermore, the lock nose component includes a lock nose seat, a horizontal slide plate, a slide plate knob, a guide seat, a guide rail, a transmission screw, a screw knob, a lock nose clamp plate, a lock nose clamp rod, a hinge rod, a release spring, and a clamping screw. The lock nose seat is provided with a horizontal sliding groove, and the horizontal slide plate is provided with an adjustment through groove. The slide plate knob passes through the adjustment through groove and is threadedly connected to the lock nose seat. The guide seat is vertically fixed to the end of the horizontal slide plate, and the guide rail is vertically fixed to the guide seat. One end of the lock nose clamp plate is slidably mounted on the guide rail. The transmission screw is rotatably mounted on the guide seat and threadedly engaged with the lock nose clamp plate. The screw knob is located at the end of the transmission screw. The other end of the lock nose clamp plate engages with one end of the lock nose clamp rod. The other end of the lock nose clamp rod is fixedly mounted on the hinge rod, and the other end of the hinge rod is hinged to the lock nose clamp plate. The hinge rod is fixed to the lock nose clamp plate by the clamping screw, and the release spring is provided between the lock nose clamp plate and the hinge rod.

[0015] The beneficial effects of this invention are:

[0016] 1) In this technology, the tool clamping assembly is sequentially set on the adjustment frame via the Z-axis adjustment assembly, the dual-angle adjustment assembly, the Y-axis adjustment assembly, and the X-axis adjustment assembly. The adjustment frame is very stable on the fixed base, which can achieve precise positioning. At the same time, the operation of the Z-axis adjustment assembly, the Y-axis adjustment assembly, and the X-axis adjustment assembly is controlled by the control center, which can realize automated adjustment and effectively improve the speed of the experiment.

[0017] 2) In this technology, the angle of the experimental tool can be adjusted by the combined use of the first rotating block and the second rotating block, thus enabling the diversification of experiments.

[0018] 3) In this technology, the nose-locking component can quickly fix the nose of the animal, improving the fixation speed of the experimental animal. Attached Figure Description

[0019] Figure 1 This is a three-dimensional connection structure diagram of the stereo positioning device;

[0020] Figure 2 This is a 3D connection structure diagram of the dual-angle adjustment assembly;

[0021] Figure 3 This is a diagram showing the fit between the limiting block and the limiting groove.

[0022] Figure 4 This is a diagram showing the connection structure between the connecting block and the locking sleeve.

[0023] Figure 5 This is a diagram showing the fit between the tool tip and the tool ring.

[0024] Figure 6 A three-dimensional connection structure diagram of the brain localization component;

[0025] Figure 7 This is a diagram showing the fit between the ear rod and the ear sleeve.

[0026] Figure 8 This is a diagram showing the mating structure between the sliding bar and the locking bar;

[0027] In the diagram, 1-base, 2-adjusting bracket, 3-X-direction motor, 4-X-direction slider, 5-X-direction guide rail, 6-X-direction lead screw, 7-X-direction scale, 8-X-direction mark, 9-Y-direction motor, 10-Y-direction guide rod, 11-Y-direction lead screw, 12-Y-direction output block, 13-Y-direction fixing block, 14-Y-direction scale, 15-first rotating block, 16-second rotating block, 17-first rotating scale, 18-second rotating scale 19-First locking screw, 20-Second locking screw, 21-Limit block, 22-Central shaft, 23-Shaft locking head, 24-Limit groove, 25-Rotation groove, 26-First rotation indicator, 27-Second rotation indicator, 28-Z-axis motor, 29-Z-axis guide rod, 30-Z-axis lead screw, 31-Z-axis output block, 32-Z-axis scale, 33-Connecting block, 34-Locking sleeve, 35-Top block 36-Sliding pin, 37-Ejection spring, 38-Ejection knob, 39-Locking groove, 40-Pin groove, 41-First clamping groove, 42-Second clamping groove, 43-Tool end, 44-Tool ring, 45-Tool knob, 46-Connecting rod, 47-Tool groove, 48-Sliding plate, 49-Sliding bar, 50-Locking bar, 51-Cam handle, 52-Limiting groove, 53-Locking lug seat, 54-Ling rod 55-Ear cover, 56-Inner spring, 57-Spring plug, 58-Pressure plate, 59-Pressure knob, 60-Nose lock seat, 61-Horizontal slide plate, 62-Slide plate knob, 63-Guide seat, 64-Guide rail, 65-Drive screw, 66-Screw knob, 67-Nose clip plate, 68-Nose clip rod, 69-Hinge rod, 70-Separation spring, 71-Clamping screw, 72-Horizontal slide groove, 73-Adjusting through groove. Detailed Implementation

[0028] The technical solution of the present invention will be clearly and completely described below with reference to the embodiments. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0029] See Figures 1-8 The present invention provides a technical solution:

[0030] An automatically adjustable stereotaxic brain localization device includes a base 1, an adjustment frame 2, an X-axis adjustment component, a Y-axis adjustment component, a Z-axis adjustment component, a dual-angle adjustment component, a brain localization component, and a tool clamping component. The lower end of the adjustment frame 2 is mounted on the base 1. The X-axis adjustment component is mounted on the upper end of the adjustment frame 2. The Y-axis adjustment component is mounted on the output part of the X-axis adjustment component. The dual-angle adjustment component is mounted on the output part of the Y-axis adjustment component. The Z-axis adjustment component is mounted on the output part of the dual-angle adjustment component. The tool clamping component is mounted on the output part of the Z-axis adjustment component. The brain localization component is mounted on the base 1 and cooperates with the tool clamping component. The X-axis adjustment component, the Y-axis adjustment component, and the Z-axis adjustment component are all electrically connected to a control center. The base 1 is used to install the adjustment frame 2 and the brain positioning component. The brain positioning component is used to fix the animal's brain. The control center is existing technology. Under the control of the control center, the X-axis adjustment component, the Y-axis adjustment component and the Z-axis adjustment component work together. After passing through the X-axis adjustment component, the Y-axis adjustment component, the dual-angle adjustment component and the Z-axis adjustment component in sequence, the tool clamping component is controlled to work. The tool clamping component is used to clamp the tools used in the experiment.

[0031] In some embodiments, the X-axis adjustment assembly includes an X-axis motor 3, an X-axis slider 4, an X-axis guide rail 5, an X-axis lead screw 6, an X-axis scale 7, and an X-axis mark 8. The X-axis guide rail 5 is fixedly mounted on the top of the adjustment frame 2, the X-axis slider 4 is slidably mounted on the X-axis guide rail 5, the X-axis motor 3 is fixedly mounted on the adjustment frame 2, the X-axis lead screw 6 is mounted on the output shaft of the X-axis motor 3 and threadedly engaged with the X-axis slider 4, the top of the adjustment frame 2 is provided with an X-axis scale 7, and the X-axis slider 4 is provided with an X-axis mark 8 that engages with the X-axis scale 7. Among them, the X-axis motor 3 is a motor in the prior art and is electrically connected to the control center. The X-axis motor 3 drives the X-axis lead screw 6 to rotate, and the X-axis lead screw 6 pushes the X-axis slider 4 to slide on the X-axis guide rail 5, thereby realizing the X-axis adjustment of the tool clamping assembly. The X-axis scale 7 is set parallel to the X-axis guide rail 5. Setting the X-axis scale 7 allows you to intuitively see the distance the X-axis slider 4 has moved. The X-axis mark 8 is a triangular mark, and one of the tips of the X-axis mark 8 points to the scale of the X-axis scale 7.

[0032] In some embodiments, the Y-axis adjustment assembly includes a Y-axis motor 9, a Y-axis guide rod 10, a Y-axis lead screw 11, a Y-axis output block 12, a Y-axis fixing block 13, and a Y-axis scale 14. The Y-axis motor 9 is fixedly mounted on the Y-axis fixing block 13. The Y-axis guide rod 10 passes through the X-axis slider 4 and is fixedly connected to the Y-axis output block 12. The two ends of the Y-axis scale 14 are respectively mounted on the Y-axis output block 12 and the Y-axis fixing block 13. The Y-axis lead screw 11 is mounted on the output part of the Y-axis motor 9 and is threadedly engaged with the X-axis slider 4. The Y-axis motor 9 is a conventional motor and is electrically connected to the control center. Two parallel Y-axis guide rods 10 are provided. The X-axis slider 4 has two through holes that mate with the Y-axis guide rods 10. A Y-axis fixing block 13 is fixed to the Y-axis guide rod 10 to mount the Y-axis motor 9. A Y-axis output block 12 is fixed to the Y-axis guide rod 10 to mount the dual-angle adjustment assembly. A Y-axis scale 14 is provided between the Y-axis output block 12 and the Y-axis fixing block 13, allowing the movement distance of the Y-axis output block 12 to be visually observed. The Y-axis motor 9 drives the Y-axis lead screw 11 to rotate. The Y-axis lead screw 11 is threadedly engaged with the X-axis slider 4, thereby driving the tool clamping assembly to move in the Y direction.

[0033] In some embodiments, the dual-angle adjustment assembly includes a first rotating block 15, a second rotating block 16, a first rotating scale 17, a second rotating scale 18, a first locking screw 19, a second locking screw 20, a limiting block 21, a central rotating shaft 22, and a rotating shaft locking head 23. A rotating hole is provided on the Y-axis output block 12, and one end of the first rotating block 15 is rotatably disposed within the rotating hole. The Y-axis output block 12 and the first rotating block 15 are fixedly connected by the first locking screw 19. A limiting block 21 is fixedly provided on the Y-axis output block 12, and a limiting groove 24 that cooperates with the limiting block 21 is provided on the first rotating block 15. A rotating groove 25 is provided on the other end of block 15. One end of the second rotating block 16 is rotatably mounted in the rotating groove 25 via a central rotating shaft 22. The central rotating shaft 22 is fixed to the first rotating block 15 via a rotating shaft locking head 23. The second rotating block 16 is fixed to the first rotating block 15 via a second locking screw 20. A first rotating scale 17 is provided on the first rotating block 15. A first rotating mark 26 that mates with the first rotating scale 17 is provided on the Y-axis output block 12. A second rotating scale 18 is provided on the second rotating block 16. A second rotating mark 27 that mates with the second rotating scale 18 is provided on the first rotating block 15. The first rotating block 15 rotates around the axis of the rotating hole, and the second rotating block 16 rotates around the axis of the central rotating shaft 22. The axis of the rotating hole is perpendicular to the axis of the central rotating shaft 22. The axis of the rotating hole is parallel to the Y-guide rod 10, and the axis of the central rotating shaft 22 is parallel to the X-guide rail 5. The first locking screw 19 and the second locking screw 20 are both hand-tightening screws in the prior art. The first locking screw 19 is threadedly engaged with the Y-direction output block 12 and its end rests on the first rotating block 15. The second locking screw 20 is threadedly engaged with the first rotating block 15 and its end rests on the second rotating block 16. The end of the central rotating shaft 22 is provided with an internal thread, and the end of the rotating shaft locking head 23 is provided with an external thread that engages with the internal thread. With the cooperation of the central rotating shaft 22 and the rotating shaft locking head 23, the first rotating block 15 and the second rotating block 16 are connected together. A limiting block 21 is provided on the Y-direction output block 12 and is used in conjunction with the limiting groove 24 to limit the rotation range of the first rotating block 15. The outer surface of the first rotating block 15 is a cylindrical surface, and the first rotation scale 17 is provided on the cylindrical surface. The first rotation mark 26 is triangular and one of its sharp corners engages with the scale on the first rotation scale 17. The second rotation scale 18 is a sector-shaped scale, with the center of the sector on the axis of the central rotation axis 22. The second rotation mark 27 is a triangle with one of its sharp corners matching the scale on the second rotation scale 18.

[0034] In some embodiments, the Z-axis adjustment assembly includes a Z-axis motor 28, a Z-axis guide rod 29, a Z-axis lead screw 30, a Z-axis output block 31, and a Z-axis scale 32. The Z-axis guide rod 29 is slidably mounted on the second rotating block 16, the Z-axis output block 31 is fixedly mounted on the lower end of the Z-axis guide rod 29, the Z-axis motor 28 is fixedly mounted on the upper end of the Z-axis guide rod 29, the Z-axis lead screw 30 is mounted on the output part of the Z-axis motor 28 and threadedly engaged with the second rotating block 16, and the Z-axis scale 32 is mounted on the outer wall of the Z-axis guide rod 29. The Z-axis motor 28 is a conventional motor and is electrically connected to the control center. Two Z-axis guide rods 29 are provided and arranged parallel to each other. The Z-axis output block 31 is fixed on the lower end of the Z-axis guide rod 29 for mounting the tool clamping assembly. The Z-axis motor 28 is fixed on the upper end of the Z-axis guide rod 29 to drive the Z-axis lead screw 30 to rotate. The Z-axis lead screw 30 is threadedly engaged with the second rotating block 16, thereby controlling the tool clamping assembly to move up and down. Z-axis scale 32 is directly mounted on Z-axis guide rod 29. The second rotating block 16 is provided with Z-axis mark that cooperates with Z-axis scale 32. The Z-axis mark is triangular and one of the triangles is aligned with the scale on Z-axis scale 32.

[0035] In some embodiments, the tool clamping assembly includes a connecting block 33, a locking sleeve 34, a top block 35, a sliding pin 36, an ejection spring 37, an ejection knob 38, and a tool clamping component. The locking sleeve 34 has a through locking groove 39. The top block 35 is slidably disposed in and engages with the locking groove 39. Sliding pins 36 are fixedly disposed on both sides of the top block 35. Pin grooves 40 that engage with the sliding pins 36 are provided on both sides of the locking sleeve 34. One end of the top block 35... The top is provided with a first clamping groove 41, and the inner wall of the locking slide groove 39 is provided with a second clamping groove 42 that cooperates with the first clamping groove 41. The tool clamping component is located between the first clamping groove 41 and the second clamping groove 42. The other end of the top block 35 is provided with an ejection spring 37 between it and the inner wall of the locking sleeve 34. The ejection spring 37 is sleeved on the ejection knob 38. The ejection knob 38 and the locking sleeve 34 are threadedly engaged. The top block 35 is fixed to the Z-direction output block 31 by the connecting block 33. The connecting block 33 is used to fix the top block 35 to the Z-direction output block 31. The top block 35 is symmetrically provided with sliding pins 36. With the cooperation of the pin groove 40 on the locking sleeve 34 and the sliding pin 36, the top block 35 can only move in one direction within the locking sleeve 34. Under the action of the ejection spring 37, the first clamping groove 41 and the second clamping groove 42 approach each other, thereby fixing the connecting rod 46 between the first clamping groove 41 and the second clamping groove 42. The ejection knob 38 is threadedly engaged with the locking sleeve 34. The end of the ejection knob 38 rests on the top block 35. Under the action of the ejection knob 38, the connecting rod 46 is further fixed between the first clamping groove 41 and the second clamping groove 42 and will not fall off.

[0036] In some embodiments, the tool clamping component includes a tool end 43, a tool ring 44, a tool knob 45, and a connecting rod 46. The upper end of the connecting rod 46 is disposed between the first clamping groove 41 and the second clamping groove 42. The tool end 43 is disposed on the lower end of the connecting rod 46. The tool knob 45 fixes the tool ring 44 to the outer wall of the tool end 43. A tool groove 47 is provided on the outer wall of the tool end 43. The connecting rod 46 is used to install the tool end 43. The tool groove 47 on the tool end 43 cooperates with the tool ring 44 to install the experimental tool. The tool knob 45 is threadedly engaged with the tool ring 44 and its end rests against the tool end 43, thereby fixing the tool ring 44 to the tool end 43.

[0037] In some embodiments, the brain positioning component includes a sliding plate 48, a sliding bar 49, a locking bar 50, a cam handle 51, a locking lug component, and a locking nose component. A limiting groove 52 is provided on the upper surface of the base 1. The sliding bar 49 is slidably disposed in the limiting groove 52 and cooperates with the limiting groove 52. The sliding bar 49 is fixedly connected to the sliding plate 48. A locking groove that cooperates with the limiting groove 52 is provided on the base 1. The locking bar 50 is disposed in the locking groove and one side cooperates with the sliding bar 49. The other side of the locking bar 50 cooperates with the cam handle 51 on the base 1. Sliding strips 49 are fixedly installed on both sides of the sliding plate 48. The sliding strips 49 slide in the limiting grooves 52 on the base 1, which can adjust the relative position between the sliding plate 48 and the base 1, so as to better conduct experiments. The locking strip 50 cooperates with the cam handle 51. After the cam handle 51 is rotated, it presses on the locking strip 50, and the locking strip 50 presses on the sliding strip 49, thereby fixing the sliding plate 48 on the base 1. Two locking ear parts are symmetrically arranged on the base 1. The two locking ear parts are inserted into the two ear canals of the animal respectively. The nose locking part is used to fix the animal's nose.

[0038] In some embodiments, the locking lug component includes a locking lug seat 53, a lug rod 54, a lug sleeve 55, an inner spring 56, a spring plug 57, a clamping plate 58, and a clamping knob 59. The locking lug seat 53 is fixedly mounted on the sliding plate 48, the lug sleeve 55 is fixedly mounted on the upper end of the locking lug seat 53, the spring plug 57 is mounted on one end of the lug sleeve 55, the inner spring 56 is mounted inside the lug sleeve 55 and one end engages with the spring plug 57, the lug rod 54 is mounted inside the other end of the lug sleeve 55 and engages with the other end of the inner spring 56, the locking lug seat 53 is provided with a clamping plate 58 for fixing the lug rod 54, and the locking lug seat 53 is fixed to the locking lug seat 53 by the clamping knob 59. The locking ear seat 53 is used to install the ear cover 55, and the ear cover 55 is used to install the ear rod 54. In order to facilitate the extension and retraction adjustment of the ear rod 54, an inner spring 56 and a spring plug 57 are provided in the ear cover 55. Under the action of the inner spring 56, one person can fix the animal's brain. The clamping plate 58 is provided with a through hole for the clamping knob 59. The clamping knob 59 is threadedly engaged with the locking ear seat 53. The ear rod 54 can be fixed on the locking ear seat 53 by using the clamping plate 58 and the clamping knob 59 together.

[0039] In some embodiments, the lock nose assembly includes a lock nose seat 60, a horizontal slide plate 61, a slide plate knob 62, a guide seat 63, a guide rail 64, a transmission screw 65, a screw knob 66, a lock nose clamp 67, a lock nose clamp rod 68, a hinge rod 69, a release spring 70, and a clamping screw 71. The lock nose seat 60 is provided with a horizontal groove 72, and the horizontal slide plate 61 is provided with an adjustment groove 73. The slide plate knob 62 passes through the adjustment groove 73 and is threadedly connected to the lock nose seat 60. The guide seat 63 is vertically fixed to the end of the horizontal slide plate 61, and is vertically fixedly mounted on the guide seat 63. There is a guide rail 64, one end of the nose clip 67 is slidably mounted on the guide rail 64, the transmission screw 65 is rotatably mounted on the guide seat 63 and threadedly engaged with the nose clip 67, the screw knob 66 ​​is mounted on the end of the transmission screw 65, the other end of the nose clip 67 engages with one end of the nose clip rod 68, the other end of the nose clip rod 68 is fixedly mounted on the hinge rod 69, the other end of the hinge rod 69 is hinged to the nose clip 67, the hinge rod 69 is fixed to the nose clip 67 by a clamping screw 71, and a separation spring 70 is provided between the nose clip 67 and the hinge rod 69. The locking nose seat 60 is fixed on the sliding plate 48. A horizontal sliding groove 72 is provided on the locking nose seat 60, and an adjustment through groove 73 is provided on the horizontal sliding plate 61. The adjustment through groove 73 works in conjunction with the sliding plate knob 62 to allow the horizontal sliding plate 61 to move closer to or further away from the lug 54. The horizontal sliding plate 61 is used to install the guide seat 63. The guide rail 64, the transmission screw 65, and the screw knob 66 ​​on the guide seat 63 work together to adjust the nose clip 67 to move up and down in the vertical direction. The screw knob 66 ​​drives the transmission screw 65 to rotate. The transmission screw 65 is threadedly engaged with the nose clip 67. The guide rail 64 guides the movement of the nose clip 67. The nose clip 67 is Z-shaped. One end of the hinge rod 69 is hinged to the nose clip 67, and the nose clip rod 68 is connected to the other end of the hinge rod 69. The release spring 70 is sleeved on the clamping screw 71. The hinge rod 69 has a through hole that mates with the clamping screw 71. The clamping screw 71 is threadedly engaged with the nose clip 67. The function of the release spring 70 is to separate the hinge rod 69 from the nose clip 67. The clamping screw 71 brings the hinge rod 69 and the nose clip 67 closer together.

[0040] In the description of this invention, it should be understood that the terms "upper", "lower", "bottom", "one end", "top", "middle", "other end", "coaxial", "one side", "inner", "front", "center", "both ends", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing this invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this invention.

[0041] In this invention, unless otherwise explicitly specified and limited, the terms "set", "install", "connect", "fix", "hinged", etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components or the interaction between two components. Unless otherwise explicitly limited, those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0042] The above description is merely a preferred embodiment of the present invention. It should be understood that the present invention is not limited to the forms disclosed herein and should not be construed as excluding other embodiments. It can be used in various other combinations, modifications, and environments, and can be altered within the scope of the concept described herein through the above teachings or related technologies or knowledge. Modifications and variations made by those skilled in the art that do not depart from the spirit and scope of the present invention should be within the protection scope of the appended claims.

Claims

1. An automatically adjustable stereotaxic instrument for the brain, characterized in that: The device includes a base (1), an adjustment frame (2), an X-axis adjustment component, a Y-axis adjustment component, a Z-axis adjustment component, a dual-angle adjustment component, a brain positioning component, and a tool clamping component. The lower end of the adjustment frame (2) is disposed on the base (1), the X-axis adjustment component is disposed on the upper end of the adjustment frame (2), the Y-axis adjustment component is disposed on the output part of the X-axis adjustment component, the dual-angle adjustment component is disposed on the output part of the Y-axis adjustment component, the Z-axis adjustment component is disposed on the output part of the dual-angle adjustment component, the tool clamping component is disposed on the output part of the Z-axis adjustment component, and the brain positioning component is disposed on the base (1) and cooperates with the tool clamping component. The X-axis adjustment component, the Y-axis adjustment component, and the Z-axis adjustment component are all electrically connected to the control center. The X-axis adjustment assembly includes an X-axis motor (3), an X-axis slider (4), an X-axis guide rail (5), an X-axis lead screw (6), an X-axis scale (7), and an X-axis mark (8). The X-axis guide rail (5) is fixedly mounted on the top of the adjustment frame (2). The X-axis slider (4) is slidably mounted on the X-axis guide rail (5). The X-axis motor (3) is fixedly mounted on the adjustment frame (2). The X-axis lead screw (6) is mounted on the output shaft of the X-axis motor (3) and threadedly engaged with the X-axis slider (4). The X-axis scale (7) is mounted on the top of the adjustment frame (2). The X-axis mark (8) is mounted on the X-axis slider (4) and engages with the X-axis scale (7). The Y-axis adjustment assembly includes a Y-axis motor (9), a Y-axis guide rod (10), a Y-axis lead screw (11), a Y-axis output block (12), a Y-axis fixing block (13), and a Y-axis scale (14). The Y-axis motor (9) is fixedly mounted on the Y-axis fixing block (13). The Y-axis guide rod (10) passes through the X-axis slider (4) and is fixedly connected to the Y-axis output block (12). The two ends of the Y-axis scale (14) are respectively mounted on the Y-axis output block (12) and the Y-axis fixing block (13). The Y-axis lead screw (11) is mounted on the output part of the Y-axis motor (9) and is threadedly engaged with the X-axis slider (4). The dual-angle adjustment assembly includes a first rotating block (15), a second rotating block (16), a first rotating scale (17), a second rotating scale (18), a first locking screw (19), a second locking screw (20), a limiting block (21), a central rotating shaft (22), and a rotating shaft locking head (23). The Y-axis output block (12) has a rotating hole. One end of the first rotating block (15) is rotatably disposed within the rotating hole. The Y-axis output block (12) and the first rotating block (15) are fixedly connected by the first locking screw (19). The limiting block (21) is fixedly disposed on the Y-axis output block (12). The first rotating block (15) has a limiting groove (24) that cooperates with the limiting block (21). The other end of the first rotating block (15) has a... A rotating groove (25) is provided. One end of the second rotating block (16) is rotatably disposed in the rotating groove (25) via the central rotating shaft (22). The central rotating shaft (22) is fixed on the first rotating block (15) via the rotating shaft locking head (23). The second rotating block (16) is fixed on the first rotating block (15) via the second locking screw (20). The first rotating block (15) is provided with the first rotating scale (17). The Y-direction output block (12) is provided with the first rotating mark (26) that cooperates with the first rotating scale (17). The second rotating block (16) is provided with the second rotating scale (18). The first rotating block (15) is provided with the second rotating mark (27) that cooperates with the second rotating scale (18).

2. The automatically adjustable stereotaxic brain localization device according to claim 1, characterized in that: The Z-axis adjustment assembly includes a Z-axis motor (28), a Z-axis guide rod (29), a Z-axis lead screw (30), a Z-axis output block (31), and a Z-axis scale (32). The Z-axis guide rod (29) is slidably mounted on the second rotating block (16). The Z-axis output block (31) is fixedly mounted on the lower end of the Z-axis guide rod (29). The Z-axis motor (28) is fixedly mounted on the upper end of the Z-axis guide rod (29). The Z-axis lead screw (30) is mounted on the output part of the Z-axis motor (28) and threadedly engaged with the second rotating block (16). The Z-axis scale (32) is mounted on the outer wall of the Z-axis guide rod (29).

3. The automatically adjustable stereotaxic brain localization device according to claim 2, characterized in that: The tool clamping assembly includes a connecting block (33), a locking sleeve (34), a top block (35), a sliding pin (36), an ejection spring (37), an ejection knob (38), and a tool clamping component. The locking sleeve (34) has a through locking groove (39). The top block (35) is slidably disposed in the locking groove (39) and cooperates with the locking groove (39). The sliding pin (36) is fixedly disposed on both sides of the top block (35). The locking sleeve (34) has a pin groove (40) on both sides that cooperates with the sliding pin (36). A first clamping device is disposed on one end of the top block (35). The inner wall of the locking groove (39) is provided with a second clamping groove (42) that cooperates with the first clamping groove (41). The tool clamping component is disposed between the first clamping groove (41) and the second clamping groove (42). The other end of the top block (35) is provided with the ejection spring (37) between it and the inner wall of the locking sleeve (34). The ejection spring (37) is sleeved on the ejection knob (38). The ejection knob (38) and the locking sleeve (34) are threadedly engaged. The top block (35) is fixed on the Z-direction output block (31) by the connecting block (33).

4. The automatically adjustable stereotaxic brain localization device according to claim 3, characterized in that: The tool clamping component includes a tool end (43), a tool ring (44), a tool knob (45), and a connecting rod (46). The upper end of the connecting rod (46) is disposed between the first clamping groove (41) and the second clamping groove (42). The tool end (43) is disposed on the lower end of the connecting rod (46). The tool knob (45) fixes the tool ring (44) on the outer wall of the tool end (43). A tool groove (47) is provided on the outer wall of the tool end (43).

5. An automatically adjustable stereotaxic brain localization device according to any one of claims 1-4, characterized in that: The brain positioning component includes a sliding plate (48), a sliding bar (49), a locking bar (50), a cam handle (51), a locking lug component, and a locking nose component. A limiting groove (52) is provided on the upper surface of the base (1). The sliding bar (49) is slidably disposed in the limiting groove (52) and cooperates with the limiting groove (52). The sliding bar (49) is fixedly connected to the sliding plate (48). A locking groove is provided on the base (1) to cooperate with the limiting groove (52). The locking bar (50) is disposed in the locking groove and cooperates with the sliding bar (49) on one side. The other side of the locking bar (50) cooperates with the cam handle (51) on the base (1).

6. The automatically adjustable stereotaxic brain localization device according to claim 5, characterized in that: The locking lug component includes a locking lug seat (53), a lug rod (54), a lug sleeve (55), an inner spring (56), a spring plug (57), a clamping plate (58), and a clamping knob (59). The locking lug seat (53) is fixedly mounted on the sliding plate (48). The lug sleeve (55) is fixedly mounted on the upper end of the locking lug seat (53). The spring plug (57) is mounted on one end of the lug sleeve (55). The inner spring (56) is mounted inside the lug sleeve (55) and one end cooperates with the spring plug (57). The lug rod (54) is mounted inside the other end of the lug sleeve (55) and cooperates with the other end of the inner spring (56). The locking lug seat (53) is provided with the clamping plate (58) for fixing the lug rod (54). The lug rod (54) is fixed on the locking lug seat (53) by the clamping knob (59).

7. The automatically adjustable stereotaxic device according to claim 5, characterized in that: The lock nose assembly includes a lock nose seat (60), a horizontal slide plate (61), a slide plate knob (62), a guide seat (63), a guide rail (64), a transmission screw (65), a screw knob (66), a nose clamp plate (67), a nose clamp rod (68), a hinge rod (69), a release spring (70), and a clamping screw (71). The lock nose seat (60) has a horizontal slide groove (72), and the horizontal slide plate (61) has an adjustment slot (73). The slide plate knob (62) passes through the adjustment slot (73) and is threadedly connected to the lock nose seat (60). The guide seat (63) is vertically fixed to the end of the horizontal slide plate (61), and the guide rail (64) is vertically fixed to the guide seat (63). One end of the clamp (67) is slidably mounted on the guide rail (64). The transmission screw (65) is rotatably mounted on the guide seat (63) and threadedly engaged with the nose clamp (67). The screw knob (66) is mounted on the end of the transmission screw (65). The other end of the nose clamp (67) is engaged with one end of the nose clamp rod (68). The other end of the nose clamp rod (68) is fixedly mounted on the hinge rod (69). The other end of the hinge rod (69) is hinged to the nose clamp (67). The hinge rod (69) is fixed to the nose clamp (67) by the clamping screw (71). The separation spring (70) is provided between the nose clamp (67) and the hinge rod (69).

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