South five-ingredient pseudo-ginseng bone healing plaster and preparation method thereof

Abstract

The invention provides a south five-ingredient pseudo-ginseng bone healing plaster and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine external preparations. The medicinal liquor comprises the following raw materials in parts by weight: 10 parts of kadsura longepedunculata root powder, 2 parts of pseudo-ginseng powder, 0.5 part of ligusticum wallichii powder, 0.5 part of glutinous rice flour, 3 parts of 62-degree white spirit and 10 parts of honey. According to the invention, specific traditional Chinese medicinal raw materials are selected and scientifically proportioned, and an advanced preparation process is combined, so that the bone fracture treatment plaster which is remarkable in curative effect, stable in quality and high in safety is prepared, and clinical treatment and market requirements are met.

Description

Technical Field

[0001] The invention provides a Nanwuwei Sanqi Yugu plaster and a preparation method thereof, belonging to the technical field of external-use preparations of traditional Chinese medicine. Background Art

[0002] In the field of Traditional Chinese Medicine, topical plasters for the treatment of bone injuries and diseases have attracted widespread attention due to their ease of use and significant efficacy. While traditional plasters for bone injuries have some efficacy, they lack the selection and proportion of ingredients, as well as the preparation process.

[0003] Some plasters have irregular raw material sources, resulting in unstable efficacy. Some plasters fail to fully consider the raw material characteristics during the preparation process, affecting the release and absorption of the active ingredients. Furthermore, some plasters have packaging and storage defects, which can easily lead to product deterioration and shorten shelf life. Therefore, it is of great significance to develop a plaster for treating bone injuries with scientifically sound ingredients, advanced preparation technology, and stable and reliable quality.

[0004] Therefore, in view of this, the existing structure is studied and improved, and a Nanwuwei Sanqi Bone Healing Plaster and a preparation method thereof are proposed to solve the above-mentioned problems. Summary of the Invention

[0005] The present invention aims to provide a Nanwuwei Sanqi Bone Healing Plaster and a preparation method thereof. By selecting specific Chinese medicinal materials, scientifically proportioning, and combining advanced preparation technology, a bone injury treatment plaster with significant efficacy, stable quality, and high safety is prepared to meet clinical treatment and market needs.

[0006] In order to solve the above problems, the present invention proposes a technical solution: a Southern Schisandra chinensis and Panax notoginseng bone healing plaster and a preparation method thereof, the raw materials comprising, by weight: 10 parts of Southern Schisandra chinensis root powder, 2 parts of Panax notoginseng powder, 0.5 parts of Chuanxiong powder, 0.5 parts of glutinous rice flour, 3 parts of 62-proof liquor, and 10 parts of honey.

[0007] Furthermore, the Schisandra chinensis root powder is made from the rhizome, skin and flesh of Schisandra chinensis collected in autumn and winter, which are washed, dried, ground and then passed through a 300-mesh filter screen; the Panax notoginseng powder and Chuanxiong powder are both made from the corresponding Chinese medicinal materials, which are washed, dried, ground and passed through a 300-mesh filter screen.

[0008] Furthermore, the honey is pure natural mature honey with a Baume degree of not less than 42 degrees, and is tested to be free of antibiotics, pesticide residues and heavy metals exceeding the standard.

[0009] Furthermore, the 62-proof liquor is brewed from pure grains, the main ingredients of which are water and ethanol, and does not contain any harmful additives.

[0010] Furthermore, the roots of Schisandra chinensis need to be selected from plants with a growth period of more than 5 years and no diseases or insect pests.

[0011] Furthermore, the preparation method is as follows:

[0012] Put Schisandra chinensis root powder, Panax notoginseng powder, Chuanxiong powder and glutinous rice flour into a container and mix well;

[0013] Add 62% liquor and stir to moisten the powder;

[0014] Add honey and continue stirring until a uniform paste is formed. When adding honey and stirring, the temperature should be controlled at 40-50℃ to ensure the fluidity of honey and the full mixing of the raw materials. Constant temperature stirring equipment should be used for the operation.

[0015] Put the ointment into a Chinese medicine external application bag and seal it for storage.

[0016] Furthermore, in the process of uniformly stirring the Schisandra chinensis root powder, Panax notoginseng powder, Chuanxiong powder and glutinous rice flour, the stirring speed is 100-150 rpm, the stirring time is 10-15 minutes, and the stirring container needs to be made of stainless steel to avoid chemical reaction with the raw materials.

[0017] Furthermore, the Chinese medicine external application bag is made of breathable non-woven fabric with a thickness of 0.1-0.2 mm, and the external application bag needs to be sterilized with ethylene oxide before use. After the ointment-like paste is made into a patch and put into the Chinese medicine external application bag, it needs to be vacuum-sealed and packaged, and the packaging environment needs to meet the 100,000-level cleanliness standard.

[0018] Furthermore, each patch weighs 10-15 grams, measures 10 cm x 12 cm, and has an anti-sticking isolation layer made of medical silicone paper. The patch has a shelf life of 24 months at room temperature (25°C), and the active ingredient content does not decrease by more than 5% during the shelf life.

[0019] Due to the adoption of the above technical solution, the beneficial effects of the Nanwuwei Sanqi Bone Healing Plaster and the preparation method thereof of the present invention are:

[0020] Schisandra chinensis root has nourishing and strengthening properties, dispelling wind and dampness; Panax notoginseng dissipates blood stasis, stops bleeding, reduces swelling, and relieves pain; and Chuanxiong promotes blood circulation and qi, dispels wind and relieves pain. Together, these three ingredients offer a synergistic effect in treating bone injuries and diseases. Furthermore, strict regulations are in place regarding the source, processing methods, and quality standards of raw materials. For example, Schisandra chinensis root is sourced from plants of a specific age and health, and honey and liquor meet quality standards. This ensures the quality of the raw materials and the stability of their efficacy.

[0021] 2. During the preparation process, precise control of parameters such as stirring speed, time, and temperature ensures thorough mixing of all raw materials, facilitating the uniform distribution and release of the active ingredients. The use of stainless steel mixing vessels, sterilization of TCM external application bags, and packaging in a clean environment enhance product safety and quality stability.

[0022] 3. The patch has a reasonable dosage form design, and its size and weight are suitable for application to different parts of the human body; the anti-sticking isolation layer is convenient for use; the shelf life is long and the active ingredients are stable, making it easy to store and transport, meeting market demand. DETAILED DESCRIPTION

[0023] The following is a clear and complete description of the technical solutions in the embodiments of the present invention. It is obvious that the embodiments described are only part of the embodiments of the present invention, not all of them. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts are within the scope of protection of the present invention.

[0024] Example 1

[0025] Preparation of raw materials: Weigh according to weight proportions 10 kg of Schisandra chinensis root powder (made from the bark and flesh of Schisandra chinensis rhizomes collected in autumn and winter that are more than 5 years old and free of pests and diseases, which are washed, dried, ground, and sieved through a 300-mesh filter), 2 kg of Panax notoginseng powder (made from Panax notoginseng washed, dried, ground, and sieved through a 300-mesh filter), 0.5 kg of Chuanxiong powder (made from Chuanxiong washed, dried, ground, and sieved through a 300-mesh filter), 0.5 kg of glutinous rice flour, 3 kg of 62-proof pure grain-brewed liquor, and 10 kg of pure natural mature honey with a Baume degree of more than 42 degrees (tested to contain no antibiotics, pesticide residues, or excessive heavy metals).

[0026] Preparation process:

[0027] Put the Schisandra chinensis root powder, Panax notoginseng powder, Chuanxiong powder and glutinous rice flour into a stainless steel container, stir at a stirring speed of 100 rpm for 15 minutes, and stir thoroughly.

[0028] Add 62-proof liquor and stir to moisten the powder.

[0029] Control the temperature in the container at 40°C, add honey, and continue stirring using a constant temperature stirring device until a uniform ointment is formed.

[0030] The ointment-like paste is put into a breathable non-woven Chinese medicine external application bag that has been sterilized with ethylene oxide. The thickness of the external application bag is 0.1 mm, and then it is vacuum-sealed and packaged. The packaging environment meets the 100,000-level cleanliness standard.

[0031] The plasters are made with a weight of 10 grams per patch and a size of 10 cm×12 cm, and medical silicone oil paper is pasted on the surface as an anti-sticking isolation layer.

[0032] Testing and storage: After testing, the shelf life of this batch of plasters at room temperature (25°C) is 24 months, and the content of active ingredients does not decrease by more than 5% during the shelf life.

[0033] Example 2

[0034] Raw material preparation: Weigh by weight 10 kg of Schisandrae Chinensis Root Powder, 2 kg of Panax Notoginseng Powder, 0.5 kg of Chuanxiong Powder, 0.5 kg of glutinous rice flour, 3 kg of 62% pure grain brewed liquor, and 10 kg of pure natural mature honey with a degree of Baume of 43%. The preparation and quality requirements of each raw material are the same as those in Example 1.

[0035] Preparation process:

[0036] Put Schisandra chinensis root powder, Panax notoginseng powder, Chuanxiong powder and glutinous rice flour into a stainless steel container, stir at a stirring speed of 150 rpm for 10 minutes and mix thoroughly.

[0037] Add white wine to initially moisten the powder.

[0038] Control the temperature at 50°C, add honey, and stir using a constant temperature stirring device until a uniform ointment is formed.

[0039] The paste is put into a 0.2 mm thick, breathable non-woven Chinese medicine external application bag that has been sterilized and vacuum-sealed (the packaging environment meets the 100,000-level cleanliness standard).

[0040] A plaster with a weight of 15 grams and a size of 10 cm×12 cm was prepared, and medical silicone oil paper was pasted as an anti-sticking isolation layer.

[0041] Testing and storage: After inspection, the shelf life of this batch of plasters at room temperature (25°C) is 24 months, and the decrease in the content of active ingredients during the shelf life is in compliance with the standards and does not exceed 5%.

[0042] The present invention and its implementation methods are described above. This description is not restrictive. In short, if ordinary technicians in this field are inspired by it and do not depart from the purpose of the invention, they can creatively design structures and embodiments similar to the technical solution, which should fall within the scope of protection of the present invention.

Claims

1. A Nanwuwei Sanqi Bone Healing Plaster and a preparation method thereof, characterized in that: The raw materials include, by weight: 10 parts of Schisandra chinensis root powder, 2 parts of Panax notoginseng powder, 0.5 parts of Chuanxiong powder, 0.5 parts of glutinous rice flour, 3 parts of 62-proof liquor, and 10 parts of honey.

2. The Nanwuwei Sanqi Bone Healing Plaster and its preparation method according to claim 1, characterized in that: The Schisandra chinensis root powder is prepared by washing, drying, grinding and filtering through a 300-mesh filter screen the rhizome, skin and flesh of Schisandra chinensis collected in autumn and winter; the Panax notoginseng powder and Chuanxiong powder are prepared by washing, drying and grinding the corresponding Chinese medicinal materials and filtering through a 300-mesh filter screen.

3. The Nanwuwei Sanqi Bone Healing Plaster and its preparation method according to claim 1, characterized in that: The honey is pure natural mature honey with a Baume degree of not less than 42 degrees, and has been tested to be free of antibiotics, pesticide residues and heavy metals exceeding the standard.

4. The Nanwuwei Sanqi Bone Healing Plaster and its preparation method according to claim 1, characterized in that: The 62-proof liquor is brewed from pure grains, with water and ethanol as the main ingredients, and does not contain any harmful additives.

5. The Nanwuwei Sanqi Bone Healing Plaster and its preparation method according to claim 1, characterized in that: The Schisandra chinensis root should be selected from rhizomes of plants that have been growing for more than 5 years and are free of diseases and insect pests.

6. A Nanwuwei Sanqi Yugu Plaster and a preparation method thereof according to claim 1, wherein the preparation method is as follows: Put Schisandra chinensis root powder, Panax notoginseng powder, Chuanxiong powder and glutinous rice flour into a container and mix well; Add 62% liquor and stir to moisten the powder; Add honey and continue stirring until a uniform paste is formed. When adding honey and stirring, the temperature should be controlled at 40-50℃ to ensure the fluidity of honey and the full mixing of the raw materials. Constant temperature stirring equipment should be used for the operation. Put the ointment into a Chinese medicine external application bag and seal it for storage.

7. A Nanwuwei Sanqi Yugu Plaster and a preparation method thereof according to claim 6, wherein the preparation method is as follows: during the process of uniformly stirring the Nanwuwei Sanqi root powder, Panax notoginseng powder, Chuanxiong powder, and glutinous rice flour, the stirring speed is 100-150 rpm, the stirring time is 10-15 minutes, and the stirring container must be made of stainless steel to avoid chemical reaction with the raw materials.

8. A Nanwuwei Sanqi Yugu Plaster and a preparation method thereof according to claim 6, wherein the preparation method is as follows: the Chinese medicine external application bag is made of a breathable non-woven fabric with a thickness of 0.1-0.2 mm, and the external application bag needs to be sterilized with ethylene oxide before use. After the ointment-like paste is made into a plaster and loaded into the Chinese medicine external application bag, it needs to be vacuum-sealed and packaged, and the packaging environment needs to meet the 100,000-level cleanliness standard.

9. The Nanwuwei Sanqi Bone Healing Plaster and its preparation method according to claim 6, wherein each plaster weighs 10-15 grams, measures 10 cm x 12 cm, and is provided with an anti-sticking isolation layer made of medical silicone oil paper. The plaster has a shelf life of 24 months at room temperature (25°C), and the active ingredient content does not decrease by more than 5% during the shelf life.