Hyperspectral Imaging Device and Control Method for the Anterior Segment

Abstract

This application provides a hyperspectral imaging device for the anterior segment of the anterior segment, comprising: an illumination optical path including a light source; an imaging optical path; a first beam splitter for splitting the light emitted from the imaging optical path into reflected light and transmitted light; an image acquisition optical path for receiving reflected light and converting the reflected light's optical signal into an electrical signal; a hyperspectral data acquisition optical path for receiving transmitted light; a scanning mirror with an adjustable angle; and a controller configured to adjust the deflection angle of the scanning mirror based on the position of the anterior segment region to be detected contained in the image, so that the light reflected from the anterior segment region to be detected can be projected into the hyperspectral data acquisition optical path along its optical axis. The device provided by this application offers doctors more reference information for disease classification and diagnosis, significantly reduces the impact of eye tremors on spectral data, and improves accuracy.

Description

Technical Field

[0001] This application relates to the field of medical device technology, specifically to a hyperspectral imaging device and control method for the anterior segment of the eye. Background Technology

[0002] The anterior segment of the eyeball generally includes the tear film, cornea, anterior chamber, iris, and lens. Anterior segment examination is one of the basic ophthalmological examinations and is of great significance for screening or diagnosing eye diseases such as dry eye, glaucoma, keratitis, and cataracts. Common anterior segment imaging equipment includes slit-lamp microscopes, optical coherence tomography (OCT) scanners, and confocal scanning microscopes.

[0003] However, the aforementioned devices can only acquire spatial structural information of the anterior segment lesions. The information collected by these devices can only be used by doctors to make morphological diagnoses. Further diagnosis of certain lesions (such as keratitis) requires laboratory testing after scraping the lesion tissue, which is an invasive procedure. This results in low acceptance by examinees, long examination cycles, and high costs. Summary of the Invention

[0004] To at least partially solve the above-mentioned problems, according to a first aspect of this application, this application provides a hyperspectral imaging device for the anterior segment of the eye, comprising: an illumination optical path including a light source for illuminating a human eye; an imaging optical path, wherein light projected from the light source passes through the illumination optical path and enters the human eye, and light reflected by the human eye enters the imaging optical path; a first beam splitter, wherein light reflected by the human eye passes through the imaging optical path and exits, reaching the first beam splitter, the first beam splitter being used to split the light emitted from the imaging optical path into reflected light and transmitted light; an image acquisition optical path, wherein the image acquisition optical path is used to receive the reflected light and convert the optical signal of the reflected light into an electrical signal to obtain an image of the human eye, the image being used to determine the location of the detection area of ​​the anterior segment of the human eye; and a hyperspectral imaging device. According to the acquisition optical path, the hyperspectral data acquisition optical path is used to receive transmitted light and convert the optical signal of the transmitted light into an electrical signal to obtain the hyperspectral data of the human eye; the scanning mirror has an adjustable angle, and the transmitted light emitted from the first beam splitter is reflected by the scanning mirror and enters the hyperspectral data acquisition optical path; the controller is connected to the image acquisition optical path, the hyperspectral data acquisition optical path and the scanning mirror, and the controller is configured to: adjust the deflection angle of the scanning mirror based on the position of the anterior segment to be detected in the image, so that the light reflected from the anterior segment to be detected, after being transmitted by the first beam splitter and reflected by the scanning mirror, can be projected into the hyperspectral data acquisition optical path along the optical axis direction of the hyperspectral data acquisition optical path.

[0005] In some embodiments, the hyperspectral data acquisition optical path includes a first imaging lens, a through hole, a first collimating lens, and a hyperspectral acquisition component arranged coaxially along the optical path; the light reflected by the scanning mirror is focused by the first imaging lens, passes through the through hole, and is then collimated by the first collimating lens before reaching the hyperspectral acquisition component.

[0006] In some embodiments, the hyperspectral acquisition component includes a bandpass filter, a dispersion device, a second imaging lens, and a linear photodetector. Light collimated by the first collimating lens passes through the bandpass filter, is separated by the dispersion device, and then focused by the second imaging lens onto the linear photodetector. The linear photodetector is connected to a controller and is used to convert the optical signal into an electrical signal containing hyperspectral data.

[0007] In some embodiments, the diameter of the through-hole is adjustable, and the portion outside the through-hole is coated with a matte material.

[0008] In some embodiments, the image acquisition optical path includes a third imaging lens and an area array photodetector; the reflected light emitted by the first beam splitter is focused by the third imaging lens and reaches the area array photodetector, which is connected to the controller and is used to convert the optical signal into an electrical signal containing human eye image data.

[0009] In some embodiments, the illumination optical path further includes a condenser lens, a first aperture, a projection lens, and a second beam splitter arranged coaxially along the optical path in sequence; the light emitted by the light source is imaged at the first aperture after passing through the condenser lens, then passes through the first aperture, is collimated by the projection lens and reaches the second beam splitter, and is reflected by the second beam splitter into the human eye; the light reflected by the human eye reaches the second beam splitter and is transmitted through the second beam splitter into the imaging optical path.

[0010] In some embodiments, the imaging optical path includes a fourth imaging lens, a second aperture, a fifth imaging lens, and a second collimating lens arranged coaxially along the optical path in sequence; the light reflected by the human eye passes through the fourth imaging lens, the second aperture, and the fifth imaging lens in sequence, and then reaches the second collimating lens, and after being collimated by the second collimating lens, it reaches the first beam splitter.

[0011] In some embodiments, the image-side focal point of the fourth imaging lens and the object-side focal point of the fifth imaging lens coincide, and the second aperture stop is located at the image-side focal plane of the fourth imaging lens.

[0012] According to a second aspect of this application, this application provides a control method for the aforementioned hyperspectral imaging device. The control method includes: acquiring an image of a human eye through an image acquisition optical path; determining the position of the anterior segment of the human eye to be detected in the image; determining, based on the position of the anterior segment to be detected in the image, the offset of the image formed by the anterior segment to be detected relative to the corresponding position of the optical axis of the image acquisition optical path in the image; and determining the adjustment angle of the scanning mirror based on the offset.

[0013] In some embodiments, the adjustment angle of the scanning mirror in the X direction The adjustment angle of the scanning mirror in the Y direction ,in, It is the offset in the X direction of the image of the anterior segment to be detected relative to the corresponding position of the optical axis of the image acquisition optical path in the image. f1 is the offset in the Y direction of the image formed by the anterior segment of the region to be detected relative to the corresponding position of the optical axis of the image acquisition optical path in the image. f2 is the focal length of the imaging lens used for imaging on the photodetector in the hyperspectral data acquisition optical path. The X and Y directions are perpendicular to each other.

[0014] The hyperspectral imaging device and control method for the anterior segment provided in this application acquire images of the human eye through an image acquisition optical path, and designates abnormal areas in the human eye image as the anterior segment to be detected. Then, by adjusting the scanning mirror, the hyperspectral data acquisition optical path selectively acquires spectral information of the anterior segment to be detected, providing doctors with more reference for disease classification and diagnosis. Furthermore, because the spectral information of the anterior segment to be detected is acquired only locally, it avoids the disadvantages of hyperspectral imaging, such as long acquisition time, large data volume, and a large amount of redundant data. It can efficiently complete the acquisition of spectral information of the anterior segment to be detected, with fast acquisition speed and small data volume, significantly reducing the impact of human eye tremor on spectral data, improving accuracy, and greatly improving the compliance of the examinee. Attached Figure Description

[0015] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 This is a schematic diagram of a hyperspectral imaging device for the anterior segment of the eye provided in an embodiment of this application;

[0017] Figure 2This is a schematic diagram illustrating the offset of the image formed by the anterior segment to be detected relative to the optical axis of the image acquisition optical path, provided by an embodiment of this application.

[0018] Figure 3 This is a schematic diagram showing the position of the image formed by the anterior segment of the area to be detected in the photodetector before the scanning mirror is adjusted in an embodiment of this application.

[0019] Figure 4 This is a schematic diagram showing the position of the image formed by the anterior segment of the area to be detected in the photodetector after the angle of the scanning mirror is adjusted according to an embodiment of this application.

[0020] The attached figures are labeled as follows:

[0021] 1. Human eye; 2. Second beam splitter; 3. Fourth imaging lens; 4. Second aperture; 5. Fifth imaging lens; 6. Second collimating lens; 7. First beam splitter; 8. Scanning mirror; 9. First imaging lens; 10. Through hole; 11. First collimating lens; 12. Bandpass filter; 13. Dispersion device; 14. Second imaging lens; 15. Linear array photodetector; 16. Third imaging lens; 17. Area array photodetector; 18. Projection mirror; 19. First aperture; 20. Condenser lens; 21. Light source.

[0022] It should be understood that the dimensions of the various parts shown in the accompanying drawings are not drawn to actual scale. Furthermore, the same or similar reference numerals denote the same or similar components. Detailed Implementation

[0023] The preferred embodiments of this application will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are merely some, not all, of the embodiments of this invention. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection claimed in this application.

[0024] The terms "first," "second," and similar words used in this application do not indicate any order, quantity, or importance, but are merely used to distinguish different parts. Words such as "including" or "contains" mean that the element preceding the word encompasses the element listed after it, and do not exclude the possibility of encompassing other elements as well. Terms such as "above," "below," "left," and "right" are used only to indicate relative positional relationships; when the absolute position of the described object changes, this relative positional relationship may also change accordingly.

[0025] According to the first aspect of this application, this application provides a hyperspectral imaging device for the anterior segment of the eye, which acquires spectral information while obtaining images of the spatial structure of the anterior segment. By utilizing the differences in the absorption, scattering and reflection characteristics of different substances for different wavelengths of light, it provides doctors with more reference for the classification and diagnosis of diseases, improves diagnostic compliance and efficiency, and reduces examination costs.

[0026] like Figure 1 As shown, the hyperspectral imaging device includes: an illumination optical path, an imaging optical path, a first beam splitter 7, an image acquisition optical path, a hyperspectral data acquisition optical path, a scanning mirror 8, and a controller. In this embodiment, the illumination optical path, imaging optical path, first beam splitter 7, image acquisition optical path, hyperspectral data acquisition optical path, and scanning mirror 8 can all be mounted on the same movable support. The position of the movable support can be adjusted to change the distance between the hyperspectral imaging device and the human eye 1 to be tested, so that the human eye 1 can be precisely within the imaging field of view and achieve clear imaging.

[0027] The illumination optical path includes a light source 21 for illuminating the human eye 1. The light source 21 includes, but is not limited to, a continuous light source 21 and a pulsed light source 21. The spectrum of the light source 21 is a continuous spectrum, preferably in the visible and near-infrared bands. The light projected by the light source 21 passes through the illumination optical path and enters the human eye 1. The light reflected by the human eye 1 enters the imaging optical path, which focuses and collimates the light reflected from the human eye 1. The light reflected from the human eye 1 exits through the imaging optical path and reaches the first beam splitter 7. The first beam splitter 7 separates the light emitted from the imaging optical path into reflected light and transmitted light, which enter the image acquisition optical path and the hyperspectral data acquisition optical path, respectively. The first beam splitter 7 can be an intensity beam splitter or a dichroic beam splitter, etc. The image acquisition optical path receives the reflected light and converts the light signal of the reflected light into an electrical signal to obtain an image of the human eye 1. The image is used to determine the location of the anterior segment of the human eye 1 to be detected. The location of the anterior segment of the human eye 1 to be detected can be determined by a doctor observing the image or by a pre-set image recognition algorithm within the device.

[0028] The hyperspectral data acquisition optical path is used to receive transmitted light and convert the optical signal of the transmitted light into an electrical signal to obtain hyperspectral data for the human eye 1. Different substances have different absorption, scattering, and reflection characteristics for different wavelengths of light. Therefore, specific substances can be identified through spectral data, which is different from traditional image data that only records a few discrete bands (such as RGB color images and multispectral remote sensing images). Hyperspectral data can capture the fine spectral features of ground objects (or targets) in continuous spectral bands, thereby achieving accurate target identification, component analysis, and attribute inversion. The angle of the scanning mirror 8 is adjustable. The transmitted light emitted from the first beam splitter 7 is reflected by the scanning mirror 8 and enters the hyperspectral data acquisition optical path. The scanning mirror 8 can be adjusted at least in the mutually perpendicular X and Y directions to change the direction in which the light enters the hyperspectral data acquisition optical path. The controller is connected to the image acquisition optical path, the hyperspectral data acquisition optical path, and the scanning mirror 8. The controller is configured to adjust the deflection angle of the scanning mirror 8 based on the position of the anterior segment to be detected region contained in the image. This ensures that the light reflected from the anterior segment to be detected region, after being transmitted through the first beam splitter 7 and reflected by the scanning mirror 8, can be projected into the hyperspectral data acquisition optical path along its optical axis. In this embodiment, through the adjustment of the controller, the light reflected from the anterior segment to be detected region can accurately enter the hyperspectral data acquisition optical path, thereby enabling the hyperspectral data acquisition optical path to perform targeted spectral analysis on the anterior segment to be detected region.

[0029] The hyperspectral imaging device for the anterior segment provided in this application acquires an image of the human eye 1 through an image acquisition optical path, and identifies abnormal areas in the image of the human eye 1 as the anterior segment to be detected. Then, by adjusting the scanning reflector 8, the hyperspectral data acquisition optical path selectively acquires the spectral information of the anterior segment to be detected, providing doctors with more reference for disease classification and diagnosis. Furthermore, since the spectral information of the anterior segment to be detected is acquired only locally, it avoids the disadvantages of hyperspectral imaging, such as long time consumption, large data volume, and a large amount of redundant data. It can efficiently complete the acquisition of spectral information of the anterior segment to be detected, with fast acquisition speed and small data volume, significantly reducing the impact of human eye 1 tremor on spectral data, improving accuracy, and greatly improving the compliance of the examinee.

[0030] The following example illustrates how hyperspectral imaging assists doctors in diagnosing corneal infections. Common types of corneal infections include bacterial, viral, and fungal infections. Doctors need to confirm the type of infection to prescribe targeted medication. Different pathogens exhibit differences in waveform, peak value, and wavelength due to variations in their protein and nucleic acid components. First, an image of the human eye is used to locate the clearly infected lesion area as the anterior segment to be tested. Then, the differences in spectral absorption peaks within the anterior segment are further analyzed. For example, fungi have hyphae, bacteria have cell membranes, numerous metabolic enzymes, and RNA, while viruses are almost entirely composed of capsid proteins encapsulating concentrated nucleic acids. This leads to significant differences in their absorption spectral characteristics. Specifically, fungal hyphae have unique melanin absorption peaks; while bacterial cell walls, cell membranes, and some endogenous pigments (such as chlorophyll and carotene) produce specific absorption peaks in the visible light region (400-700 nm), which is the basis for bacterial classification and identification; viruses completely lack these structures and pigments, thus exhibiting no characteristic absorption in the visible light region. The hyperspectral imaging device provided in this application can assist doctors in quickly diagnosing the type of corneal infection, at least partially replacing the identification process of traditional laboratory tests.

[0031] In some embodiments, the hyperspectral data acquisition optical path includes a first imaging lens 9, a through-hole 10, a first collimating lens 11, and a hyperspectral acquisition component arranged coaxially along the optical path. Light reflected by the scanning mirror 8 is focused by the first imaging lens 9, passes through the through-hole 10, and is then collimated by the first collimating lens 11 before reaching the hyperspectral acquisition component. In this embodiment, the first imaging lens 9 concentrates the light at the through-hole 10, increasing the intensity of the light signal and providing a sufficient light signal basis for subsequent hyperspectral data acquisition. The through-hole 10 can filter the light signal. Preferably, the diameter of the through-hole 10 is adjustable to accommodate different sizes of anterior segment detection areas. The portion outside the through-hole 10 (e.g., a support, baffle, etc.) is coated with an exfoliating material to eliminate stray light from non-anterior segment detection areas and prevent stray light from interfering with the accuracy of the hyperspectral data. The first collimating lens 11 can collimate the converging light passing through the through-hole 10 back into parallel light, providing stable parallel light conditions for the spectral separation of the subsequent dispersive device 13. Parallel light ensures that the spectral signals of different wavelengths are uniform and without shift after dispersion, guaranteeing the accuracy of hyperspectral data. The hyperspectral acquisition component is used to acquire optical signals to obtain hyperspectral data.

[0032] In some embodiments, the hyperspectral acquisition component includes a bandpass filter 12, a dispersion device 13, a second imaging lens 14, and a linear photodetector 15. Light collimated by the first collimating lens 11 passes through the bandpass filter 12, is separated by the dispersion device 13, and then focused by the second imaging lens 14 onto the linear photodetector 15. The linear photodetector 15 is connected to a controller and is used to convert the optical signal into an electrical signal containing hyperspectral data. The bandpass filter 12 filters out light in irrelevant wavelength ranges, allowing only light in the target wavelength range to pass through (such as specific bands adapted for anterior segment tissue spectral analysis), further purifying the optical signal, reducing interference from irrelevant wavelengths on subsequent spectral analysis, and improving the signal-to-noise ratio of the hyperspectral data. The dispersive device 13 includes, but is not limited to, prisms, gratings, prism-grating combinations, and tunable filters. The dispersive device 13 separates the parallel light collimated by the first collimating lens 11 according to wavelength (i.e., dispersion), decomposing the composite light into monochromatic light of different wavelengths to form spectral information of the anterior segment to be detected, providing the basis for spectral dimension acquisition of hyperspectral data. The second imaging lens 14 focuses the spectral signal separated by the dispersive device 13 onto the linear array photodetector 15, completing the final optical path focusing for hyperspectral imaging and ensuring the clarity of the spectral signal. The linear array photodetector 15 converts the spectral signal focused by the second imaging lens 14 into an electrical signal, forming hyperspectral data of the anterior segment to be detected (containing light intensity information at different wavelengths); this data is transmitted to the controller for analysis and processing.

[0033] In some embodiments, the image acquisition optical path includes a third imaging lens 16 and a planar photodetector 17. Reflected light emitted from the first beam splitter 7 is focused by the third imaging lens 16 and reaches the planar photodetector 17. The planar photodetector 17 is connected to a controller and is used to convert the optical signal into an electrical signal containing image data of the human eye 1. In this embodiment, the third imaging lens 16 receives the light reflected from the first beam splitter 7 and focuses it onto the planar photodetector 17, completing the final optical path focusing for structural imaging and ensuring the clarity of the two-dimensional geometric space image. The planar photodetector 17 converts the optical signal focused by the third imaging lens 16 into an electrical signal, forming a two-dimensional geometric space image of the human eye 1. This image can be used to select the anterior segment of the eye to be detected and can also provide doctors with more reference information for the classification and diagnosis of diseases that do not require hyperspectral recognition.

[0034] In some embodiments, the illumination optical path further includes a condenser lens 20, a first aperture 19, a projection lens 18, and a second beam splitter 2 arranged coaxially along the optical path. Light emitted from the light source 21 is imaged at the first aperture 19 after passing through the condenser lens 20, then passes through the first aperture 19, is collimated by the projection lens 18, and reaches the second beam splitter 2, where it is reflected into the human eye 1. The light reflected from the human eye 1 reaches the second beam splitter 2 and is transmitted through it into the imaging optical path. In this embodiment, the condenser lens 20 is used to converge the diverging light emitted from the light source 21, focusing the light onto the subsequent first aperture 19, reducing light loss, improving light utilization, and providing sufficient and concentrated light for the subsequent optical path. The first aperture 19 is used to adjust the shape of the illumination light; for example, the first aperture 19 can be a circular aperture or a slit (the slit is used for slit lamp inspection). The first aperture 19 can be a variable aperture to allow adjustment of the diameter of the circular aperture and the length and width of the slit. The projection lens 18 collimates the converging light at the first aperture 19 into parallel light, ensuring the stability and uniformity of the illumination light and avoiding uneven brightness in the illumination area caused by light divergence, thus providing stable incident light for subsequent optical paths. The second beam splitter 2 is used to change the direction of the illumination light path to reflect the parallel light collimated by the projection lens 18 into the human eye 1, completing the final guidance of the illumination light; at the same time, by adjusting its own position and angle, it can achieve coaxial / non-coaxial incidence of the illumination light and the imaging optical path.

[0035] In some embodiments, the imaging optical path includes a fourth imaging lens 3, a second aperture 4, a fifth imaging lens 5, and a second collimating lens 6 arranged coaxially along the optical path. Light reflected from the human eye 1 passes sequentially through the fourth imaging lens 3, the second aperture 4, and the fifth imaging lens 5 before reaching the second collimating lens 6. After being collimated by the second collimating lens 6, it reaches the first beam splitter 7. Preferably, in some embodiments, the image-side focal point of the fourth imaging lens 3 and the object-side focal point of the fifth imaging lens 5 coincide, and the second aperture 4 is located at the image-side focal plane of the fourth imaging lens 3. It is understood that the anterior surface of the eyeball is curved, and the distance between different positions of the eyeball and the imaging optical path may vary, which can adversely affect the quality of hyperspectral data. Therefore, in this embodiment, the above-described arrangement allows the fourth imaging lens 3, the second aperture 4, and the fifth imaging lens 5 to form a dual telecentric optical path, eliminating the influence of different eyeball positions not being on the same plane on imaging. This ensures that the anterior segment of the eyeball to be detected maintains almost constant resolution and intensity across the entire image plane, improving the quality of hyperspectral imaging.

[0036] Please see Figure 2 , Figure 3 and Figure 4According to a second aspect of this application, this application provides a control method for the above-mentioned hyperspectral imaging device. The control method includes: acquiring an image of a human eye 1 through an image acquisition optical path; determining the position of the anterior segment of the human eye 1 to be detected in the image; determining, based on the position of the anterior segment to be detected in the image, the offset of the image formed by the anterior segment to be detected relative to the corresponding position of the optical axis of the image acquisition optical path in the image; and determining the adjustment angle of the scanning mirror 8 based on the offset. Figure 2 In the image, the entire grid area represents the image of the human eye 1 acquired by the image acquisition optical path. The cross-shaped marker (red) indicates the corresponding position of the optical axis of the image acquisition optical path in the image, and the dot marker (black) indicates the position of the anterior segment of the eye to be detected in the image. Figure 3 neutralization Figure 4 In the diagram, the dashed line represents the light reflected from the anterior segment of the eye, and the dotted line represents the optical axis of the light path.

[0037] In some embodiments, the adjustment angle of the scanning mirror 8 in the X direction The adjustment angle of the scanning mirror 8 in the Y direction ,in, It is the offset in the X direction of the image of the anterior segment to be detected relative to the corresponding position of the optical axis of the image acquisition optical path in the image. f1 is the offset in the Y direction of the image formed by the anterior segment of the region to be detected relative to the corresponding position of the optical axis of the image acquisition optical path in the image. f2 is the focal length of the imaging lens (second imaging lens 14) used for imaging on the photodetector in the hyperspectral data acquisition optical path. f2 is the focal length of the imaging lens (third imaging lens 16) used for imaging on the photodetector in the image acquisition optical path. The X and Y directions are perpendicular to each other. The X direction can be horizontal and the Y direction can be vertical.

[0038] The method of using the hyperspectral imaging device provided in this application is as follows:

[0039] Step S1: Turn on the light source 21 of the illumination optical path, adjust the first aperture 19 as needed to illuminate the human eye 1, acquire the image of the human eye 1 through the image acquisition optical path, and move the movable bracket according to the acquired image so that the human eye 1 is located within the imaging field of view of the hyperspectral imaging device and is clearly imaged.

[0040] Step S2: The user selects the anterior segment to be detected in the image of the human eye 1 obtained by the image acquisition optical path. The controller calculates and adjusts the deflection angle of the scanning mirror 8 to obtain the hyperspectral data of the anterior segment to be detected.

[0041] Step S3: After analyzing and processing the image of the human eye 1 acquired by the image acquisition optical path and the hyperspectral data acquired by the hyperspectral data acquisition optical path, the image is presented to the user as a reference for the user's diagnosis.

[0042] Based on the various embodiments of this application described above, in the absence of explicit denial or conflict, the technical features of one embodiment may be advantageously combined with one or more other embodiments.

[0043] While specific embodiments of this application have been described in detail by way of examples, those skilled in the art should understand that the above examples are for illustrative purposes only and are not intended to limit the scope of this application. Those skilled in the art should understand that modifications can be made to the above embodiments or equivalent substitutions can be made to some technical features without departing from the scope and spirit of this application. The scope of this application is defined by the appended claims.

Claims

1. A hyperspectral imaging device for the anterior segment of the eye, characterized in that, include: An illumination optical path, the illumination optical path including a light source for illuminating the human eye; An imaging optical path is provided, wherein the light projected by the light source passes through the illumination optical path and enters the human eye, and the light reflected by the human eye enters the imaging optical path. The first beam splitter is used to separate the light emitted from the imaging optical path into reflected light and transmitted light. An image acquisition optical path is provided, which is used to receive the reflected light and convert the optical signal of the reflected light into an electrical signal to obtain an image of the human eye. The image is used to determine the location of the anterior segment of the human eye to be detected. A hyperspectral data acquisition optical path is provided to receive the transmitted light and convert the optical signal of the transmitted light into an electrical signal to obtain hyperspectral data of the human eye. A scanning mirror, the angle of which is adjustable, allows transmitted light emitted from the first beam splitter to enter the hyperspectral data acquisition optical path after being reflected by the scanning mirror. A controller is connected to the image acquisition optical path, the hyperspectral data acquisition optical path, and the scanning mirror. The controller is configured to adjust the deflection angle of the scanning mirror based on the position of the anterior segment to be detected region contained in the image, so that the light reflected from the anterior segment to be detected region, after being transmitted through the first beam splitter and reflected by the scanning mirror, can be projected into the hyperspectral data acquisition optical path along the optical axis direction of the hyperspectral data acquisition optical path. The imaging optical path includes a fourth imaging lens, a second aperture, a fifth imaging lens, and a second collimating lens arranged coaxially along the optical path in sequence. The light reflected by the human eye passes sequentially through the fourth imaging lens, the second aperture, and the fifth imaging lens before reaching the second collimating lens. After being collimated by the second collimating lens, it reaches the first beam splitter. The image-side focal point of the fourth imaging lens coincides with the object-side focal point of the fifth imaging lens. The second aperture is located at the image-side focal plane of the fourth imaging lens. The fourth imaging lens, the second aperture, and the fifth imaging lens form a double telecentric optical path.

2. The hyperspectral imaging device according to claim 1, characterized in that, The hyperspectral data acquisition optical path includes a first imaging lens, a through hole, a first collimating lens, and a hyperspectral acquisition component arranged coaxially along the optical path. The light reflected by the scanning mirror is focused by the first imaging lens, passes through the through hole, and is then collimated by the first collimating lens before reaching the hyperspectral acquisition component.

3. The hyperspectral imaging device according to claim 2, characterized in that, The hyperspectral acquisition component includes a bandpass filter, a dispersion device, a second imaging lens, and a linear photodetector. After being collimated by the first collimating lens, the light passes through the bandpass filter and is separated by the dispersive device. Then, it is focused by the second imaging lens onto the linear array photodetector, which is connected to the controller. The linear array photodetector is used to convert the optical signal into an electrical signal containing hyperspectral data.

4. The hyperspectral imaging device according to claim 2, characterized in that, The diameter of the through hole is adjustable, and the portion outside the through hole is coated with a matte material.

5. The hyperspectral imaging device according to claim 1, characterized in that, The image acquisition optical path includes a third imaging lens and an area array photodetector; The reflected light emitted by the first beam splitter is focused by the third imaging lens and reaches the area array photodetector. The area array photodetector is connected to the controller and is used to convert the optical signal into an electrical signal containing human eye image data.

6. The hyperspectral imaging device according to claim 1, characterized in that, The illumination optical path also includes a condenser lens, a first aperture, a projection lens, and a second beam splitter arranged coaxially along the optical path in sequence. The light emitted by the light source is imaged at the first aperture after passing through the condenser lens, then passes through the first aperture, is collimated by the projection lens and reaches the second beam splitter, and is reflected by the second beam splitter into the human eye; The light reflected by the human eye reaches the second beam splitter and is transmitted through the second beam splitter into the imaging optical path.

7. A control method for the hyperspectral imaging apparatus according to any one of claims 1-6, characterized in that, include: Images of the human eye are acquired through an image acquisition optical path; Determine the location of the region to be detected in the anterior segment of the human eye within the image; Based on the position of the anterior segment to be detected region in the image, determine the offset of the image formed by the anterior segment to be detected region relative to the corresponding position of the optical axis of the image acquisition optical path in the image; Based on the offset, the adjustment angle of the scanning mirror is determined.

8. The control method according to claim 7, characterized in that, The adjustment angle of the scanning mirror in the X direction , The adjustment angle of the scanning mirror in the Y direction , in, It is the offset in the X direction of the image of the anterior segment to be detected relative to the corresponding position of the optical axis of the image acquisition optical path in the image. f1 is the offset in the Y direction of the image formed by the anterior segment of the region to be detected relative to the corresponding position of the optical axis of the image acquisition optical path in the image. f2 is the focal length of the imaging lens used for imaging on the photodetector in the hyperspectral data acquisition optical path. The X and Y directions are perpendicular to each other.

Images