Mixing equipment for heparin products
The multi-directional mixing device addresses uneven mixing in heparin production by incorporating a stirring and circulation system, ensuring uniform distribution and reducing production time and stratification.
Patent Information
- Application Number
- CN202422486685.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-15
- Publication Date
- 2024-12-10
- Estimated Expiration
- 2034-10-15
AI Technical Summary
Existing heparin product mixing equipment suffers from uneven mixing and stratification due to one-way rotation, which can lead to inconsistencies in the final product.
A multi-directional mixing device with a stirring structure, circulation system, and discharge mechanism, utilizing motors, sprockets, and conveyor belts for precise control and uniform distribution of heparin components.
The device ensures thorough mixing, reduces production time, and enhances product consistency and safety by eliminating stratification, improving efficiency and versatility.
Smart Images

Figure CN222131625U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of organic chemical production equipment, in particular to a mixing device for heparin products. Background Art
[0002] The technical field involved in the utility model is that the heparin product mixing equipment is mainly used in the pharmaceutical industry, especially in the process of producing and preparing heparin drugs. It is used to evenly mix different raw materials, such as heparin sodium, auxiliary drug components, etc., to ensure the consistency of each batch of products; help complete the preparation process of different dosage forms of heparin drugs, such as injections, tablets, etc.; during the mixing process, stabilizers, preservatives, etc. can be added to assist in preserving the active ingredients of the drug; the equipment is usually equipped with efficient mixing blades or stirring systems to ensure that the components are fully mixed; some equipment has a temperature control function to meet the mixing requirements of different components at different temperatures; the design usually supports aseptic operation to prevent the drug from being contaminated during the production process; modern equipment usually has automatic control, allowing precise setting of mixing time and speed, and improving production efficiency and quality control. It has multiple meanings. Through an efficient mixing process, production efficiency is greatly improved and the production cycle is shortened. Ensure that the quality and efficacy of each batch of products are consistent, and improve the efficacy and safety of drugs. Meet the strict requirements of the pharmaceutical industry for the production process. Through automation and standardized operations, the risk of human error and cross contamination is reduced, ensuring the safety of drugs.
[0003] Overall, heparin product mixing equipment plays a key role in the heparin pharmaceutical process, providing efficient, safe and stable production support.
[0004] For example, a utility model entitled "A Heparin Sodium Product Mixing Device" and having a publication number of CN215196594U comprises a bracket, on which a rotatable drum for mixing heparin sodium products and a driving device for driving the drum to rotate are provided, the driving device is connected to the drum, and a plurality of baffle structures are provided in the drum. The utility model can quickly mix the heparin sodium product in the drum by placing heparin sodium in the rotatable drum and driving the drum to rotate by providing the rotatable drum.
[0005] The prior art only provides a one-way rotation which may lead to uneven mixing or severe stratification. Utility Model Content
[0006] In view of the deficiencies of the prior art, the utility model provides a mixing device for heparin products, which solves the technical problem that the prior art only provides one-way rotation, which may lead to uneven mixing or serious stratification.
[0007] To achieve the above objectives, the utility model is implemented through the following technical solutions: a mixing device for heparin products, including a main base, a column is fixedly installed on the upper wall of the main base, a mixing box is fixedly installed on the upper wall of the column, a feeding structure is fixedly installed on the upper wall of the mixing box, a circulation structure is fixedly installed on the side wall of the mixing box, a stirring structure is installed in the mixing box, a three-way pipe is installed at the lower end of the mixing box, a connecting valve is rotatably installed in the three-way pipe, the input end of the three-way pipe is connected to the lower end of the mixing box, the three-way pipe is provided with a pair of output ends, one of the output ends is connected to the input end of the circulation structure, the other of the output ends is installed with a discharge pipe, and a discharge structure is installed above the main base.
[0008] Preferably, the stirring structure includes a first motor and a stirring rod, the first motor is fixedly installed between the columns and located on the lower wall of the mixing box, a driving sprocket is fixedly installed on the driving end of the first motor, the stirring rod is rotatably installed in the mixing box, a driven sprocket is fixedly installed on the lower end of the stirring rod, the driving sprocket and the driven sprocket are meshed and connected with a transmission chain, a stirring blade is fixedly installed on the stirring rod, the stirring blade is an upward concave blade, and a material penetration hole is opened on the stirring blade.
[0009] Preferably, the feeding structure includes a feeding pipe, the feeding pipe is fixedly installed on the upper end of the mixing box, a branch pipe is provided on the feeding pipe, an exhaust port is provided on the upper end of the feeding pipe, a heating pipe is fixedly installed outside the mixing box, and an insulation cover is fixedly installed outside the mixing box.
[0010] Preferably, the circulation structure includes a circulation pipe, the circulation pipe is fixedly mounted on the column, the circulation pipe is connected to the output end of the three-way pipe, and the upper end of the circulation pipe is connected to the upper end of the mixing box.
[0011] Preferably, a second motor is fixedly mounted on the lower end of the circulation pipe, a circulation shaft is fixedly mounted on the driving end of the second motor, a spiral lifting blade is fixedly mounted on the circulation shaft, and the spiral lifting blade is rotatably mounted in the circulation pipe.
[0012] Preferably, the discharge structure includes a third motor and a conveyor belt, the third motor is fixedly mounted on the upper wall of the main base, a driving pulley is fixedly mounted on the driving end of the third motor, a driven pulley is rotatably mounted on the main base, and the conveyor belt is connected to the driving pulley and the driven pulley.
[0013] Preferably, a solenoid valve is provided on the discharge pipe.
[0014] Beneficial Effects
[0015] The utility model provides a mixing device for heparin products. The utility model adopts a multi-directional mixing design, solves the problem of uneven mixing or severe stratification caused by traditional unidirectional rotation, and greatly improves the mixing effect; equipped with a reasonable stirring structure, the mixture can be fully stirred to ensure uniform distribution of various components; the efficiency of adding and discharging materials is improved, and the waiting time in the operation process is reduced; the motor-driven design can realize precise automatic control, high processing efficiency, and stable operation; the equipment is suitable for mixing a variety of heparin products and has good versatility and flexibility. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 This is a schematic diagram of the main structure of a mixing device for heparin products described in the utility model.
[0017] In the figure: 1, main engine base; 2, column; 3, mixing box; 4, three-way pipe; 5, connecting valve; 6, discharge pipe; 7, first motor; 8, stirring rod; 9, driving sprocket; 10, driven sprocket; 11, transmission chain; 12, stirring blade; 13, feeding pipe; 14, branch pipe; 15, heating pipe; 16, insulation sleeve; 17, circulation pipe; 18, second motor; 19, circulation shaft; 20, third motor; 21, conveyor belt; 22, driving pulley; 23, driven pulley; 24, solenoid valve; DETAILED DESCRIPTION
[0018] In order to further explain the technical means and effects adopted by the present invention to achieve the predetermined purpose of the utility model, the technical scheme in the embodiment of the utility model will be clearly and completely described below in combination with the drawings in the embodiment of the utility model. Obviously, the described embodiment is only a part of the embodiment of the utility model, rather than all the embodiments. The detailed description is as follows.
[0019] See also Figure 1 The utility model provides a technical solution: a mixing device for heparin products, comprising a main base 1, a column 2 is fixedly installed on the upper wall of the main base 1, a mixing box 3 is fixedly installed on the upper wall of the column 2, a feeding structure is fixedly installed on the upper wall of the mixing box 3, a circulation structure is fixedly installed on the side wall of the mixing box 3, a stirring structure is installed in the mixing box 3, a three-way pipe 4 is installed at the lower end of the mixing box 3, a connecting valve 5 is rotatably installed in the three-way pipe 4, the input end of the three-way pipe 4 is connected to the lower end of the mixing box 3, the three-way pipe 4 is provided with a pair of output ends, one of the output ends is connected to the input end of the circulation structure, the other of the output ends is installed with a discharge pipe 6, and a discharge structure is installed above the main base 1.
[0020] The present embodiment is further configured as follows: the stirring structure includes a first motor 7 and a stirring rod 8, the first motor 7 is fixedly installed between the columns 2 and located at the lower wall of the mixing box 3, a driving sprocket 9 is fixedly installed on the driving end of the first motor 7, the stirring rod is rotatably installed in the mixing box 3, a driven sprocket 10 is fixedly installed on the lower end of the stirring rod, the driving sprocket 9 and the driven sprocket 10 are meshed and connected with a transmission chain 11, a stirring blade 12 is fixedly installed on the stirring rod, the stirring blade 12 is an upward concave blade, and a material penetration hole is opened on the stirring blade 12.
[0021] The present embodiment is further configured as follows: the feeding structure includes a feeding pipe 13, the feeding pipe 13 is fixedly installed on the upper end of the mixing box 3, a branch pipe 14 is provided on the feeding pipe 13, an exhaust port is provided on the upper end of the feeding pipe 13, a heating pipe 15 is fixedly installed outside the mixing box 3, and an insulation sleeve 16 is fixedly installed outside the mixing box 3.
[0022] This embodiment is further configured such that the circulation structure includes a circulation pipe 17 , the circulation pipe 17 is fixedly mounted on the column 2 , the circulation pipe 17 is connected to the output end of the three-way pipe 4 , and the upper end of the circulation tank is connected to the upper end of the mixing box 3 .
[0023] This embodiment is further configured such that a second motor 18 is fixedly mounted on the lower end of the circulation pipe 17 , a circulation shaft 19 is fixedly mounted on the driving end of the second motor 18 , a spiral lifting blade is fixedly mounted on the circulation shaft 19 , and the spiral lifting blade is rotatably mounted in the circulation pipe 17 .
[0024] This embodiment is further configured as follows: the discharge structure includes a third motor 20 and a conveyor belt 21, the third motor 20 is fixedly mounted on the upper wall of the main base 1, a driving pulley 22 is fixedly mounted on the driving end of the third motor 20, a driven pulley 23 is rotatably mounted on the main base 1, and the conveyor belt 21 is connected to the driving pulley 22 and the driven pulley 23.
[0025] This embodiment is further configured such that a solenoid valve 24 is provided on the discharge pipe 6 .
[0026] The detailed connection means are well known in the art; Figure 1 As shown, prepare the heparin raw materials that need to be mixed, including heparin powder and auxiliary materials (such as fillers, stabilizers, etc.).
[0027] All raw materials must be screened to ensure that there are no impurities and lumps so that they can be mixed evenly.
[0028] Place the mixing device on a flat surface and ensure that the main base 1 is stable.
[0029] According to the properties of the raw materials, a temperature control device is provided for the heating tube 15 to maintain an appropriate mixing temperature.
[0030] First, open the valve of the feeding pipe 13, and inject the heparin and auxiliary materials into the mixing box 3 through the feeding pipe 13 to ensure that the materials are evenly distributed.
[0031] During the charging process, the vent is opened to reduce the internal pressure.
[0032] The first motor 7 is started, and the stirring structure is driven by the rotation of the driving sprocket 9, the driven sprocket 10 and the transmission chain 11, the stirring rod starts to rotate, and the stirring blades 12 fully stir the materials in the mixing box 3.
[0033] At this time, the three-way pipe 4 connects the mixing box 3 and the circulation pipe 17, and the second motor 18 is started to drive the spiral lifting blades to circulate the materials, enhance the mixing effect, ensure that all raw materials are fully contacted, and repeatedly enter the mixing box 3.
[0034] During the mixing and circulation process, the temperature and viscosity of the equipment and the mixture are monitored in real time to ensure that the mixing effect meets the expected standards.
[0035] After the set mixing time is reached, the solenoid valve 24 is started to open the discharge pipe 6. At this time, the connecting valve 5 connects the discharge pipe 6 and the mixing box, and the product is discharged through the discharge pipe 6.
[0036] The third motor 20 is started to drive the conveyor belt 21 to transport the mixed heparin product to a subsequent processing or packaging system.
[0037] After each production cycle is completed, the mixing box 3, the feeding pipe 13, the discharge pipe 6 and the stirring structure must be thoroughly cleaned to avoid cross contamination.
[0038] Regularly check the motor, transmission chain 11, valves and other mechanical parts to ensure the normal operation of the equipment.
[0039] Operators must be trained to understand the equipment's operating procedures, safety protection, and troubleshooting methods to ensure production safety.
[0040] Establish a production record system to record in detail the source of raw materials, addition ratio, mixing time, temperature and performance indicators of the final product for each batch in order to track quality.
[0041] It should be noted that, in this document, relational terms such as first and second, etc. are merely used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations.
[0042] The above description is only a preferred embodiment of the present invention and does not constitute any form of limitation to the present invention. Although the present invention has been disclosed as a preferred embodiment as above, it is not intended to limit the present invention. Any technical personnel in this field can make some changes or modify the technical contents disclosed above into equivalent embodiments without departing from the scope of the technical solution of the present invention. However, any brief modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the technical solution of the present invention.
Claims
1. A mixing device for heparin products, comprising a main base (1), characterized in that: A column (2) is fixedly mounted on the upper wall of the main engine base (1), a mixing box (3) is fixedly mounted on the upper wall of the column (2), a feeding structure is fixedly mounted on the upper wall of the mixing box (3), a circulation structure is fixedly mounted on the side wall of the mixing box (3), a stirring structure is mounted inside the mixing box (3), a three-way pipe (4) is mounted at the lower end of the mixing box (3), a connecting valve (5) is rotatably mounted inside the three-way pipe (4), an input end of the three-way pipe (4) is connected to the lower end of the mixing box (3), the three-way pipe (4) is provided with a pair of output ends, one of the output ends is connected to the input end of the circulation structure, the other of the output ends is mounted with a discharge pipe (6), and a discharge structure is mounted above the main engine base (1).
2. A mixing device for heparin products according to claim 1, characterized in that: The stirring structure comprises a first motor (7) and a stirring rod (8), wherein the first motor (7) is fixedly mounted between the columns (2) and located on the lower wall of the mixing box (3), a driving sprocket (9) is fixedly mounted on the driving end of the first motor (7), the stirring rod is rotatably mounted in the mixing box (3), a driven sprocket (10) is fixedly mounted on the lower end of the stirring rod, the driving sprocket (9) and the driven sprocket (10) are meshedly connected with a transmission chain (11), a stirring blade (12) is fixedly mounted on the stirring rod, the stirring blade (12) is an upward concave blade, and a material penetration hole is opened on the stirring blade (12).
3. A mixing device for heparin products according to claim 1, characterized in that: The feeding structure comprises a feeding pipe (13), the feeding pipe (13) is fixedly mounted on the upper end of the mixing box (3), a branch pipe (14) is arranged on the feeding pipe (13), an exhaust port is arranged at the upper end of the feeding pipe (13), a heating pipe (15) is fixedly mounted outside the mixing box (3), and a heat preservation sleeve (16) is fixedly mounted outside the mixing box (3).
4. A mixing device for heparin products according to claim 1, characterized in that: The circulation structure comprises a circulation pipe (17), the circulation pipe (17) is fixedly mounted on the column (2), the circulation pipe (17) is connected to the output end of the three-way pipe (4), and the upper end of the circulation pipe is connected to the upper end of the mixing box (3).
5. A mixing device for heparin products according to claim 4, characterized in that: A second motor (18) is fixedly mounted on the lower end of the circulation pipe (17); a circulation shaft (19) is fixedly mounted on the driving end of the second motor (18); a spiral lifting blade is fixedly mounted on the circulation shaft (19); and the spiral lifting blade is rotatably mounted in the circulation pipe (17).
6. A mixing device for heparin products according to claim 1, characterized in that: The discharge structure comprises a third motor (20) and a conveyor belt (21); the third motor (20) is fixedly mounted on the upper wall of the main engine base (1); a driving pulley (22) is fixedly mounted on the driving end of the third motor (20); a driven pulley (23) is rotatably mounted on the main engine base (1); and the conveyor belt (21) is connected to the driving pulley (22) and the driven pulley (23).
7. A mixing device for heparin products according to claim 1, characterized in that: The discharge pipe (6) is provided with a solenoid valve (24).
