Multi-slide full-automatic chromosome karyotype analyzer

Abstract

The utility model relates to a multi-slide full-automatic chromosome karyotype analyzer, and relates to the technical field of chromosome analyzers. The device comprises an operation table, four installation plates are fixedly connected to the upper end of the operation table, two conveyors are installed among the four installation plates, two L-shaped plates are arranged between the two installation plates, a plurality of rotating rollers are rotationally connected to the inner top walls of the two L-shaped plates, and two material plates are fixedly connected among the four L-shaped plates. An analysis table is fixedly connected to the upper end of the operation table, a moving plate is arranged above the analysis table, a material pushing plate is connected to the lower portion of the moving plate through an automatic adjusting mechanism, an operation plate is fixedly connected between the two mounting plates, and the operation plate is connected with the moving plate through a material pushing mechanism to achieve movement of the moving plate; the slide can be automatically conveyed to the analysis table and pushed out of the analysis table after analysis, so that the inspection efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of chromosome analyzers, in particular to a multi-slide full-automatic chromosome karyotype analyzer. Background Art

[0002] Chromosome analyzer is a medical research instrument used in the fields of basic medicine and clinical medicine. It is mainly used for cytogenetic analysis. It can perform 24-color fluorescence analysis of chromosome karyotype, aberration, deletion, ectopy, etc. It can distinguish subtle chromosome translocations and accurately determine various complex karyotypes and some marker chromosomes of unknown origin.

[0003] The publication number is CN213977679U. A slide bin and a chromosome karyotype analyzer with the slide bin include a slide box and a slide box seat. The slide box includes a box body with a front opening and a lower base. The box body is arranged on the lower base, and the width of the lower base is greater than the width of the box body. The interior of the box body is provided with a plurality of first card slots for storing slides; the slide box seat is provided with a second card slot for accommodating the lower base, and the inner side wall of the second card slot is provided with an elastic positioning member for tightening the lower base. The slide bin provided by the utility model is provided with elastic positioning members for tightening the slide box on the second groove, the left cover plate, the right cover plate and the stopper, respectively, so that the slide box can be well clamped on the slide box seat. Therefore, the slide box will not easily fall over. The chromosome karyotype analyzer with the slide bin has the ability to store a large number of slides, which greatly improves the work efficiency and quality.

[0004] However, when testing a large number of slides, if the staff still places the slides under the analysis unit for analysis and testing as in conventional operations, this results in a large workload for the staff and slow testing efficiency. Utility Model Content

[0005] In view of the shortcomings of the prior art, the purpose of the utility model is to provide a multi-slide fully automatic chromosome karyotype analyzer, which can automatically load and unload materials, reduce the workload of staff, and improve the detection efficiency.

[0006] The above technical objectives of the utility model are achieved through the following technical solutions:

[0007] A multi-slide fully automatic chromosome karyotype analyzer comprises an operating table, wherein the upper end of the operating table is fixedly connected to four mounting plates, two conveyors are installed between the four mounting plates, wherein two L-shaped plates are arranged between two of the mounting plates, the inner top walls of the two L-shaped plates are rotatably connected to a plurality of rotating rollers, two material plates are fixedly connected between the four L-shaped plates, an analysis table is fixedly connected to the upper end of the operating table, a movable plate is arranged above the analysis table, a push plate is connected to the lower part of the movable plate through an automatic adjustment mechanism, wherein an operating plate is fixedly connected between the two mounting plates, the operating plate is connected to the movable plate through a push mechanism to realize the movement of the movable plate, the automatic adjustment mechanism comprises a slide groove and two first springs, the slide groove is opened at the lower end of the movable plate, the two first springs are fixedly connected to the inner top wall of the slide groove, and the push plate is fixedly connected to the lower ends of the two first springs.

[0008] By adopting the above technical solution, the operating table, mounting plate, conveyor, analysis table, material plate, automatic adjustment mechanism, moving plate and pushing plate cooperate to automatically transport the glass slide to the analysis table and push it out of the analysis table after analysis, thereby improving inspection efficiency.

[0009] In a preferred example, the utility model can be further configured as follows: the upper end of the push plate is fixedly connected to two T-shaped rods, and the two T-shaped rods are movably passed through the upper end of the movable plate.

[0010] By adopting the above technical solution, the T-bar and the push plate cooperate with each other, so that the moving stability of the push plate can be improved.

[0011] In a preferred example, the utility model can be further configured as follows: the pushing mechanism includes a movable groove, a screw, a screw nut and a second motor, the movable groove is opened on one side of the operating panel, the second motor is fixedly connected to one side wall of the movable groove, the screw is fixedly connected to the output end of the second motor, and the screw is rotatably connected to the other side wall of the movable groove, the screw nut is threadedly connected to the circumferential side of the screw, and the movable plate is hinged to one side wall of the screw nut.

[0012] By adopting the above technical solution, the pushing mechanism can drive the screw nut to move, and the screw nut can drive the moving plate to move, so that the moving plate can push the glass slide to move and leave the analysis table.

[0013] In a preferred example, the utility model can be further configured as follows: two sliding rods are fixedly connected between the side walls of the movable groove, and the screw nut is slidably connected to the circumferential sides of the two sliding rods.

[0014] By adopting the above technical solution, the screw nut and the sliding rod are slidably matched, which can improve the movement stability of the screw nut.

[0015] The utility model can be further configured as follows in a preferred example: a rotating mechanism is arranged on the screw nut, and the rotating mechanism includes a rectangular plate, a connecting groove, a machine base, a third motor, a rotating wheel and a second traction rope, the connecting groove is opened on a side wall of the movable groove, the rectangular plate is fixedly connected to one side of the screw nut, the machine base is fixedly connected to the upper end of the rectangular plate, the third motor is fixedly connected to one side of the machine base, and the output end of the third motor movably passes through the other side of the machine base, the rotating wheel is fixedly connected to the output end of the third motor, the second traction rope is fixedly connected to the circumferential side of the rotating wheel, and the other side of the second traction rope is fixed to the movable plate.

[0016] By adopting the above technical solution, the rotating mechanism can lift the moving plate and the pushing plate, so as to facilitate the transportation of the glass slide.

[0017] In a preferred example, the utility model can be further configured as follows: one side of the two L-shaped plates is fixedly connected with an L-shaped frame, and the two L-shaped frames are provided with a clamping mechanism, and the clamping mechanism includes a fixed plate, a rectangular groove, two second springs, two connecting rods, a double-track wheel, a delay plate, a first motor and two first traction ropes, the fixed plate is fixedly connected to one side of the operating table, the rectangular groove is opened on one side of the fixed plate, the two second springs are respectively fixedly connected to the two side walls of the rectangular groove, the two connecting rods are respectively fixed to the two second springs, the delay plate is fixedly connected to one side of the fixed plate, the first motor is fixedly connected to one side of the delay plate, the double-track wheel is fixedly connected to the output end of the first motor, the two first traction ropes are both fixedly connected to the circumferential side of the double-track wheel, and the two first traction ropes are respectively fixed to the two L-shaped frames.

[0018] By adopting the above technical solution, the clamping mechanism can adjust the positions of the L-shaped plate and the rotating roller, which is convenient for adjustment according to the width of the glass slide.

[0019] In a preferred example, the utility model can be further configured as follows: two limit rods are fixedly connected between the side walls of the rectangular groove, and the two connecting rods are slidably connected to the circumferential sides of the two limit rods.

[0020] By adopting the above technical solution, the connecting rod and the limiting rod are slidably matched, which can improve the movement stability of the connecting rod.

[0021] In summary, the present invention includes at least one of the following beneficial technical effects:

[0022] 1. An operating table, a mounting plate, a conveyor, an analysis table, a material plate, an automatic adjustment mechanism, a moving plate and a pushing plate are provided. When the glass slide is detected and analyzed on the analysis table, the rotating mechanism adjusts the positions of the moving plate and the pushing plate, and the moving plate is driven to move by the pushing mechanism, and the moving plate and the pushing plate push the glass slide to move. When the pushing plate moves from the analysis table to the material plate, when the glass slide is pushed to another conveyor, since the height of the material plate is different from that of the analysis table, the first spring pushes the pushing plate to fit the analysis table and the material plate due to its own elastic recovery, which facilitates the movement of the glass slide, and can automatically transport the glass slide to the analysis table, and push it out of the analysis table after the analysis, thereby improving the inspection efficiency.

[0023] 2. A pushing mechanism and a rotating mechanism are provided, and the second motor is started. The output end of the second motor drives the screw to rotate, and the screw nut moves on the surface of the screw, and the screw nut drives the moving plate to move, and the moving plate can drive the pushing plate to move, so that the movement of the pushing plate can push the glass slide to leave the analysis table, and the third motor is started. The third motor drives the rotating wheel to rotate, and the second traction rope is wrapped around the circumferential side of the second traction rope. The second traction rope pulls the moving plate upward to lift it up, which can facilitate the movement of the glass slide from the conveyor to the analysis table for loading, thereby realizing automatic loading. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 is a stereogram of this embodiment;

[0025] Figure 2 is a first stereoscopic cross-sectional view of the present embodiment;

[0026] Figure 3 This embodiment Figure 2 A partial enlarged view of the middle A;

[0027] Figure 4 is a second stereoscopic cross-sectional view of the present embodiment;

[0028] Figure 5 This embodiment Figure 4 A partial enlarged view of point B in the middle;

[0029] Figure 6 This embodiment Figure 4 A partial enlarged view of point C in the middle.

[0030] In the figure, 1, operating table; 2, mounting plate; 3, conveyor; 4, L-shaped plate; 5, rotating roller; 6, analysis table; 7, moving plate; 8, pushing plate; 9, automatic adjustment mechanism; 901, slide groove; 902, first spring; 903, T-shaped rod; 10, material plate; 11, clamping mechanism; 1101, fixing plate; 1102, rectangular groove; 1103, second spring; 1104, limiting rod; 1105, connecting rod; 1106, double-track wheel; 1107 , delay plate; 1108, first motor; 1109, first traction rope; 12, pushing mechanism; 1201, moving groove; 1202, screw rod; 1203, screw rod nut; 1204, sliding rod; 1205, second motor; 13, rotating mechanism; 1301, rectangular plate; 1302, connecting groove; 1303, machine base; 1304, third motor; 1305, rotating wheel; 1306, second traction rope; 14, operating panel; 15, L-shaped frame. DETAILED DESCRIPTION

[0031] The utility model is further described in detail below in conjunction with the accompanying drawings.

[0032] Example:

[0033] Reference Figure 1-6The utility model discloses a multi-slide fully automatic chromosome karyotype analyzer, comprising an operating table 1, four mounting plates 2 are fixedly connected to the upper end of the operating table 1, two conveyors 3 are installed between the four mounting plates 2, two L-shaped plates 4 are arranged between the two mounting plates 2, the inner top walls of the two L-shaped plates 4 are rotatably connected with a plurality of rotating rollers 5, two material plates 10 are fixedly connected between the four L-shaped plates 4, an analysis table 6 is fixedly connected to the upper end of the operating table 1, a moving plate 7 is arranged above the analysis table 6, and a pushing plate 8 is connected to the lower part of the moving plate 7 through an automatic adjustment mechanism 9, wherein An operating plate 14 is fixedly connected between the two mounting plates 2, and the operating plate 14 is connected to the moving plate 7 through the pushing mechanism 12 to realize the movement of the moving plate 7. The automatic adjustment mechanism 9 includes a slide 901 and two first springs 902. The slide 901 is opened at the lower end of the moving plate 7, and the two first springs 902 are fixedly connected to the inner top wall of the slide 901. The pushing plate 8 is fixedly connected to the lower ends of the two first springs 902. The conveyor 3 on one side drives the glass slide to move for loading, and the third motor 1304 is started. The third motor 1304 drives the rotating wheel 1305 to rotate, and the second traction The rope 1306 is wrapped around the circumferential side of the second traction rope 1306, and the second traction rope 1306 pulls the movable plate 7 upward, and the glass slide slides onto the analysis table 6 along with the material plate 10 and its own gravity. If the position is not suitable, it can be manually adjusted. When the analysis is completed, the second motor 1205 is started, and the output end of the second motor 1205 drives the screw rod 1202 to rotate, and the screw rod nut 1203 moves on the surface of the screw rod 1202, and the screw rod nut 1203 drives the movable plate 7 to move, and the movable plate 7 can drive the push plate 8 to move, so that the push plate 8 can push the glass slide. It leaves the analysis table 6, and the moving plate 7 is driven to move by the pushing mechanism 12. The moving plate 7 and the pushing plate 8 push the glass slide to move. When the pushing plate 8 moves to the material plate 10 on the analysis table 6, and when the glass slide is pushed to another conveyor 3, one of the two conveyors 3 is for loading and the other is for unloading. Since the height of the material plate 10 is different from that of the analysis table 6, the first spring 902 pushes the pushing plate 8 to fit the analysis table 6 and the material plate 10 due to its own elastic recovery, which facilitates the movement of the glass slide. The glass slide can be automatically transported to the analysis table 6 and pushed out of the analysis table 6 after analysis, thereby improving the inspection efficiency.

[0034] Two T-shaped rods 903 are fixedly connected to the upper end of the push plate 8, and the two T-shaped rods 903 are movably passed through the upper end of the movable plate 7. The cooperation between the T-shaped rods 903 and the push plate 8 can improve the movement stability of the push plate 8.

[0035] The pushing mechanism 12 includes a moving groove 1201, a screw rod 1202, a screw nut 1203 and a second motor 1205. The moving groove 1201 is opened on one side of the operating panel 14. The second motor 1205 is fixedly connected to one side wall of the moving groove 1201. The screw rod 1202 is fixedly connected to the output end of the second motor 1205, and the screw rod 1202 is rotatably connected to the other side wall of the moving groove 1201. The screw nut 1203 is threadedly connected to the circumferential side of the screw rod 1202. The moving plate 7 is hinged to one side wall of the screw nut 1203. The second motor 1205 is started, and the output end of the second motor 1205 drives the screw rod 1202 to rotate. The screw nut 1203 moves on the surface of the screw rod 1202. The screw nut 1203 drives the moving plate 7 to move. The moving plate 7 can drive the pushing plate 8 to move, so that the movement of the pushing plate 8 can push the glass slide to leave the analysis table 6.

[0036] Two sliding rods 1204 are fixedly connected between the side walls of the movable groove 1201, and the screw nut 1203 is slidably connected to the circumferential sides of the two sliding rods 1204. The screw nut 1203 and the sliding rod 1204 are slidably matched to improve the movement stability of the screw nut 1203.

[0037] The screw nut 1203 is provided with a rotating mechanism 13, which includes a rectangular plate 1301, a connecting groove 1302, a machine base 1303, a third motor 1304, a rotating wheel 1305 and a second traction rope 1306. The connecting groove 1302 is opened on a side wall of the moving groove 1201, the rectangular plate 1301 is fixedly connected to one side of the screw nut 1203, the machine base 1303 is fixedly connected to the upper end of the rectangular plate 1301, the third motor 1304 is fixedly connected to one side of the machine base 1303, and the output end of the third motor 1304 movably penetrates the machine base 13 On the other side of 03, the rotating wheel 1305 is fixedly connected to the output end of the third motor 1304, the second traction rope 1306 is fixedly connected to the circumferential side of the rotating wheel 1305, the other side of the second traction rope 1306 is fixed to the moving plate 7, the third motor 1304 is started, the third motor 1304 drives the rotating wheel 1305 to rotate, the second traction rope 1306 is wrapped around the circumferential side of the second traction rope 1306, the second traction rope 1306 pulls the moving plate 7 upward, which can facilitate the movement of the glass slide from the conveyor 3 to the analysis table 6 for loading, thereby realizing automatic loading.

[0038] One side of the two L-shaped plates 4 is fixedly connected with an L-shaped frame 15, and the L-shaped frame 15 is slidably connected to the mounting plate 2. The two L-shaped frames 15 are provided with a clamping mechanism 11, and the clamping mechanism 11 includes a fixed plate 1101, a rectangular groove 1102, two second springs 1103, two connecting rods 1105, a double-track wheel 1106, a delay plate 1107, a first motor 1108 and two first traction ropes 1109. The fixed plate 1101 is fixedly connected to one side of the operating table 1, and the rectangular groove 1102 is opened on one side of the fixed plate 1101. The two second springs 1103 are respectively fixedly connected to the two side walls of the rectangular groove 1102, and the two connecting rods 1105 are respectively fixed to the two second springs 1103, and the delay plate 1107 is fixedly connected to the fixed plate 1101. On one side of the fixed plate 1101, the first motor 1108 is fixedly connected to one side of the delay plate 1107, the double-track wheel 1106 is fixedly connected to the output end of the first motor 1108, and the two first traction ropes 1109 are fixedly connected to the circumferential side of the double-track wheel 1106, and the two first traction ropes 1109 are respectively fixed to the two L-shaped frames 15, and the first motor 1108 is started, and the output end of the first motor 1108 drives the double-track wheel 1106 to rotate, and the two first traction ropes 1109 pull the L-shaped frame 15 to move, so that the two L-shaped frames 15 drive the L-shaped plate 4 and the rotating roller 5 to move, so that the L-shaped plate 4 and the rotating roller 5 are close to the glass slide, and the clamping mechanism 11 can adjust the position of the L-shaped plate 4 and the rotating roller 5, which is convenient for adjustment according to the width of the glass slide.

[0039] Two limiting rods 1104 are fixedly connected between the side walls of the rectangular groove 1102, and two connecting rods 1105 are slidably connected to the circumferential sides of the two limiting rods 1104. The connecting rods 1105 and the limiting rods 1104 are slidably matched to improve the movement stability of the connecting rods 1105.

[0040] The implementation principle of the above embodiment is as follows: the conveyor 3 on one side drives the glass slide to move for loading, the third motor 1304 is started, the third motor 1304 drives the rotating wheel 1305 to rotate, the second traction rope 1306 is wrapped around the circumferential side of the second traction rope 1306, the second traction rope 1306 pulls the moving plate 7 upward, and the glass slide slides onto the analysis table 6 along with the material plate 10 and its own gravity. If the position is not suitable, it can be adjusted manually. When the analysis is completed, the second motor 1205 is started, the output end of the second motor 1205 drives the screw rod 1202 to rotate, the screw rod nut 1203 moves on the surface of the screw rod 1202, and the screw rod nut 1203 drives the moving plate 7 to move. The movable plate 7 can drive the pushing plate 8 to move, so that the movement of the pushing plate 8 can push the glass slide to make it leave the analysis table 6. The movable plate 7 is driven to move by the pushing mechanism 12. The movable plate 7 and the pushing plate 8 push the glass slide to move. When the pushing plate 8 moves to the material plate 10 on the analysis table 6, when the glass slide is pushed to another conveyor 3, one of the two conveyors 3 is for loading and the other is for unloading. Since the height of the material plate 10 is different from that of the analysis table 6, the first spring 902 pushes the pushing plate 8 to fit the analysis table 6 and the material plate 10 due to its own elastic recovery, which facilitates the movement of the glass slide. The glass slide can be automatically transported to the analysis table 6 and pushed out of the analysis table 6 after analysis, thereby improving the inspection efficiency.

[0041] The contents not described in detail in this specification belong to the prior art known to professional and technical personnel in this field.

[0042] The embodiments of this specific implementation method are all preferred embodiments of the utility model, and are not intended to limit the protection scope of the utility model. Therefore, all equivalent changes made based on the structure, shape, and principle of the utility model should be included in the protection scope of the utility model.

Claims

1. A multi-slide fully automatic chromosome karyotype analyzer, comprising an operating table (1), characterized in that: Four mounting plates (2) are fixedly connected to the upper end of the operating table (1), two conveyors (3) are installed between the four mounting plates (2), two L-shaped plates (4) are arranged between two mounting plates (2), the inner top walls of the two L-shaped plates (4) are rotatably connected to a plurality of rotating rollers (5), two material plates (10) are fixedly connected between the four L-shaped plates (4), an analysis table (6) is fixedly connected to the upper end of the operating table (1), a movable plate (7) is arranged above the analysis table (6), and the lower part of the movable plate (7) is adjusted by an automatic adjustment mechanism ( 9) is connected with a push plate (8), wherein an operating plate (14) is fixedly connected between the two mounting plates (2), and the operating plate (14) is connected to the movable plate (7) through a push mechanism (12) to realize the movement of the movable plate (7), and the automatic adjustment mechanism (9) includes a slide groove (901) and two first springs (902), wherein the slide groove (901) is opened at the lower end of the movable plate (7), and the two first springs (902) are fixedly connected to the inner top wall of the slide groove (901), and the push plate (8) is fixedly connected to the lower ends of the two first springs (902).

2. A multi-slide fully automatic chromosome karyotype analyzer according to claim 1, characterized in that: The upper end of the push plate (8) is fixedly connected to two T-shaped rods (903), and the two T-shaped rods (903) are movably connected to the upper end of the movable plate (7).

3. A multi-slide fully automatic chromosome karyotype analyzer according to claim 1, characterized in that: The pushing mechanism (12) comprises a movable groove (1201), a screw rod (1202), a screw rod nut (1203) and a second motor (1205); the movable groove (1201) is opened on one side of the operating panel (14); the second motor (1205) is fixedly connected to one side wall of the movable groove (1201); the screw rod (1202) is fixedly connected to the output end of the second motor (1205), and the screw rod (1202) is rotatably connected to the other side wall of the movable groove (1201); the screw rod nut (1203) is threadedly connected to the circumferential side of the screw rod (1202); and the movable plate (7) is hinged to one side wall of the screw rod nut (1203).

4. A multi-slide fully automatic chromosome karyotype analyzer according to claim 3, characterized in that: Two sliding rods (1204) are fixedly connected between the side walls of the movable groove (1201), and the screw nut (1203) is slidably connected to the circumferential sides of the two sliding rods (1204).

5. The multi-slide fully automatic chromosome karyotype analyzer according to claim 3, characterized in that: The screw nut (1203) is provided with a rotating mechanism (13), the rotating mechanism (13) comprising a rectangular plate (1301), a connecting groove (1302), a machine base (1303), a third motor (1304), a rotating wheel (1305) and a second traction rope (1306), the connecting groove (1302) being opened on a side wall of the moving groove (1201), the rectangular plate (1301) being fixedly connected to one side of the screw nut (1203), and the machine base (1303) being fixedly connected to the moving groove (1201). The third motor (1304) is fixedly connected to the upper end of the rectangular plate (1301), the third motor (1304) is fixedly connected to one side of the machine base (1303), and the output end of the third motor (1304) movably passes through the other side of the machine base (1303), the rotating wheel (1305) is fixedly connected to the output end of the third motor (1304), the second traction rope (1306) is fixedly connected to the circumferential side of the rotating wheel (1305), and the other side of the second traction rope (1306) is fixed to the movable plate (7).

6. The multi-slide fully automatic chromosome karyotype analyzer according to claim 1, characterized in that: One side of the two L-shaped plates (4) is fixedly connected to an L-shaped frame (15), and the two L-shaped frames (15) are provided with a clamping mechanism (11), and the clamping mechanism (11) comprises a fixed plate (1101), a rectangular groove (1102), two second springs (1103), two connecting rods (1105), a double-track wheel (1106), a delay plate (1107), a first motor (1108) and two first traction ropes (1109), the fixed plate (1101) is fixedly connected to one side of the operating table (1), the rectangular groove (1102) is opened on one side of the fixed plate (1101), and the two second springs (1103) are connected to the second motor (1108) and the second motor (1109) are connected to the second motor (1109). The springs (1103) are respectively fixedly connected to the two side walls of the rectangular groove (1102), the two connecting rods (1105) are respectively fixed to the two second springs (1103), the delay plate (1107) is fixedly connected to one side of the fixed plate (1101), the first motor (1108) is fixedly connected to one side of the delay plate (1107), the double-track wheel (1106) is fixedly connected to the output end of the first motor (1108), the two first traction ropes (1109) are both fixedly connected to the circumferential side of the double-track wheel (1106), and the two first traction ropes (1109) are respectively fixed to the two L-shaped frames (15).

7. A multi-slide fully automatic chromosome karyotype analyzer according to claim 6, characterized in that: Two limiting rods (1104) are fixedly connected between the side walls of the rectangular groove (1102), and the two connecting rods (1105) are slidably connected to the circumferential sides of the two limiting rods (1104).

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