Grinding device for biological pharmacy

Abstract

The utility model relates to the technical field of biopharmacy, and discloses a biopharmacy grinding device which comprises a grinding cylinder and a feeding pipe, the feeding pipe is installed in the grinding cylinder, a grinding assembly is installed in the grinding cylinder, a clamping assembly is installed at the bottom of the grinding cylinder, and the grinding assembly is used in cooperation with the grinding cylinder. A grinding cylinder is manually clamped at the upper end of a collecting box, a rotating handle is twisted, a rotating column rotates, a notch in the side portion of the rotating column is clamped with a grinding tip, and therefore a grinding ring is driven to rotate, a grinding ball and the side portion of the grinding tip make full contact with materials, grinding is more sufficient, and through rotation of the grinding ring, the grinding efficiency is improved. The grinding ball and the side part of the grinding tip can be more fully contacted with materials, so that the grinding contact area is increased, the effect of more effectively crushing and grinding the materials is facilitated, and the problems that in the medicine grinding process, if the grinding is insufficient, the distribution of medicine particles is not uniform, and part of particles are too large or too small, and the grinding efficiency is low are solved. The quality and the stability of the medicine are influenced.

Description

Technical Field

[0001] The utility model relates to the technical field of biopharmaceuticals, in particular to a grinding device for biopharmaceuticals. Background Art

[0002] Biopharmaceutical grinding devices are equipment designed specifically for the biopharmaceutical industry. Their main function is to process biopharmaceutical raw materials or drugs into the desired particle size and morphology through different grinding techniques. These devices use a variety of grinding methods, such as ball milling, ultrasonic grinding, cutting grinding, etc., to meet the preparation needs of different drugs. Through grinding, the particle size distribution of the drug can be accurately controlled, the solubility and bioavailability of the drug can be improved, and the quality and consistency of the product can be ensured. In addition, biopharmaceutical grinding devices can also reduce residues, improve the stability of drugs, and customize product characteristics such as particle size, shape, and surface properties to meet different pharmaceutical needs. In short, biopharmaceutical grinding devices play a vital role in biopharmaceutical production and play a key role in improving production efficiency, optimizing product quality, and ensuring drug safety.

[0003] At present, in the process of drug grinding, if the grinding is not sufficient, it may cause uneven distribution of drug particles, and some particles are too large or too small, affecting the quality and stability of the drug; therefore, it does not meet the existing needs. In this regard, we propose a grinding device for biopharmaceuticals. Utility Model Content

[0004] The utility model provides a biopharmaceutical grinding device, which has grinding balls and grinding tip sides that can more fully contact with materials, increasing the contact area for grinding, which is conducive to more effectively crushing and grinding materials. It solves the problem mentioned in the above background technology that in the process of drug grinding, if the grinding is not sufficient, the drug particles may be unevenly distributed, some particles may be too large or too small, and the quality and stability of the drug may be affected.

[0005] The utility model provides the following technical solution: a biopharmaceutical grinding device, comprising a grinding cylinder and a feed pipe, wherein the feed pipe is installed in the grinding cylinder, a grinding assembly is installed inside the grinding cylinder, a clamping assembly is installed at the bottom of the grinding cylinder, and the grinding assembly is used in conjunction with the grinding cylinder.

[0006] As an optional solution of a biopharmaceutical grinding device described in the utility model, wherein: the end of the feed pipe is connected to a material storage bowl, the material storage bowl is integrally connected to the top of the feed pipe, and the feed pipe is connected to the grinding cylinder.

[0007] As an optional solution of the biopharmaceutical grinding device described in the utility model, a plurality of fine material holes are opened on the side of the grinding cylinder, and a stirring shovel is connected to the end of the grinding cylinder.

[0008] As an optional solution of a biopharmaceutical grinding device described in the utility model, the grinding assembly includes a rotating column and a spiral disk, the rotating column is installed inside the grinding cylinder, and the spiral disk is integrated on the outside of the rotating column.

[0009] As an optional solution of a biopharmaceutical grinding device described in the utility model, wherein: the end of the rotating column is connected to a fixing rod, the fixing rod extends to the outside of the grinding cylinder, and the end of the fixing rod is sleeved with a rotating handle.

[0010] As an optional solution of a biopharmaceutical grinding device described in the utility model, wherein: a plurality of grinding rings are also sleeved on the outside of the rotating column, the outer wall of the grinding ring is connected to a grinding ball, the inner wall of the grinding ring is connected to a grinding tip, and a groove is opened on the side of the rotating column, and the groove is used intermittently in conjunction with the grinding tip.

[0011] As an optional solution of a biopharmaceutical grinding device described in the utility model, wherein: the end of the rotating column is connected to a fixed plug, and the fixed plug is clamped with the end of the grinding cylinder, the outer side of the fixed plug is connected to a sleeve, the side of the sleeve is provided with a material trough, the side of the sleeve is connected to a scraper, and the scraper is fitted with the inner wall of the grinding cylinder.

[0012] As an optional solution of a biopharmaceutical grinding device described in the utility model, the clamping assembly includes a clamping rod and a threaded bolt, the clamping rod is connected to the bottom of the grinding cylinder, and the threaded bolt is threadedly connected to the bottom of the clamping rod.

[0013] The utility model has the following beneficial effects:

[0014] 1. The biopharmaceutical grinding device, through the setting of the grinding ring, manually clamps the grinding cylinder at the upper end of the collection box, twists the rotating handle, the rotating column rotates, the notch on the side of the rotating column engages with the grinding tip, thereby driving the grinding ring to rotate, so that the grinding balls and the side of the grinding tip can fully contact the material, and the grinding is more complete. The grinding ring is rotated, and the grinding balls and the side of the grinding tip can more fully contact the material, increasing the contact area of ​​grinding, which is conducive to more effective crushing and grinding of the material, and solves the problem that in the process of drug grinding, if the grinding is not complete, the drug particles may be unevenly distributed, and some particles are too large or too small, which affects the quality and stability of the drug.

[0015] 2. The biopharmaceutical grinding device adopts the setting of sleeve and scraper. The sleeve, scraper and grinding ring cooperate. When the rotating column rotates, the scraper drives the scraper to rotate and scrape the inner wall of the grinding cylinder, avoiding the occurrence of blockage as much as possible, improving the production efficiency, and at the same time, it also realizes the timely scraping of materials from the inner wall of the grinding cylinder to prevent the accumulation and accumulation of materials during the grinding process, thereby reducing the occurrence of blockage. This helps to maintain the effect of smooth grinding. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a three-dimensional structural schematic diagram of the utility model.

[0017] Figure 2 It is a schematic diagram of the cutaway structure of the utility model.

[0018] Figure 3 This is a schematic diagram of the sleeve structure of the utility model.

[0019] Figure 4 It is a schematic diagram of the rotating column structure of the utility model.

[0020] Figure 5 This is a schematic diagram of the grinding ring structure of the utility model.

[0021] Figure 6 This is a schematic diagram of the scraper structure of the utility model.

[0022] In the figure: 110, grinding cylinder; 111, fine material hole; 112, stirring shovel; 140, feed pipe; 141, storage bowl; 160, grinding assembly; 161, rotating column; 162, spiral disk; 163, fixing rod; 164, rotating handle; 165, grinding ring; 170, grinding ball; 171, grinding tip; 172, notch; 173, fixing plug; 174, sleeve; 175, material trough; 180, scraper; 190, clamping assembly; 191, clamping rod; 192, threaded bolt. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0024] Example 1: This example aims to solve the problem that if the grinding is not sufficient, the drug particles may be unevenly distributed, some particles may be too large or too small, and the quality and stability of the drug may be affected. Figure 1-6A biopharmaceutical grinding device includes a grinding cylinder 110 and a feed pipe 140. The feed pipe 140 is installed in the grinding cylinder 110. A grinding assembly 160 is installed inside the grinding cylinder 110. A clamping assembly 190 is installed at the bottom of the grinding cylinder 110. The grinding assembly 160 is used in conjunction with the grinding cylinder 110.

[0025] A material storage bowl 141 is connected to the end of the feed pipe 140, and the material storage bowl 141 is integrally connected to the top of the feed pipe 140. The feed pipe 140 is connected to the grinding cylinder 110. A plurality of fine material holes 111 are opened on the side of the grinding cylinder 110. A stirring shovel 112 is connected to the end of the grinding cylinder 110. The grinding assembly 160 includes a rotating column 161 and a spiral disk 162. The rotating column 161 is installed inside the grinding cylinder 110, and the spiral disk 162 is integrated on the outside of the rotating column 161.

[0026] A fixing rod 163 is connected to the end of the rotating column 161, and the fixing rod 163 extends to the outside of the grinding cylinder 110. A rotating handle 164 is sleeved on the end of the fixing rod 163. A plurality of grinding rings 165 are also sleeved on the outside of the rotating column 161. A grinding ball 170 is connected to the outer wall of the grinding ring 165, and a grinding tip 171 is connected to the inner wall of the grinding ring 165. A notch 172 is opened on the side of the rotating column 161, and the notch 172 is used intermittently with the grinding tip 171. The clamping assembly 190 includes a clamping rod 191 and a threaded bolt 192. The clamping rod 191 is connected to the bottom of the grinding cylinder 110, and the threaded bolt 192 is threadedly connected to the bottom of the clamping rod 191.

[0027] In this embodiment: through the setting of the grinding ring 165, the grinding cylinder 110 is manually clamped at the upper end of the collection box, the rotating handle 164 is twisted, the rotating column 161 rotates, and the notch 172 on the side of the rotating column 161 engages with the grinding tip 171, thereby driving the grinding ring 165 to rotate, so that the grinding balls 170 and the sides of the grinding tips 171 are fully in contact with the material, and the grinding is more complete. By rotating the grinding ring 165, the grinding balls 170 and the sides of the grinding tips 171 can be more fully in contact with the material, increasing the contact area for grinding, which is conducive to more effectively crushing and grinding the material, and solves the problem that in the process of drug grinding, if the grinding is not complete, the drug particles may be unevenly distributed, and some particles may be too large or too small, affecting the quality and stability of the drug.

[0028] Embodiment 2: This embodiment is intended to promote the solution to the problem of blockage of the fine material hole 111. This embodiment is an improvement made on the basis of embodiment 1. For details, please refer to Figure 1-6A fixing plug 173 is connected to the end of the rotating column 161, and the fixing plug 173 is engaged with the end of the grinding cylinder 110. A sleeve 174 is connected to the outside of the fixing plug 173, and a material groove 175 is opened on the side of the sleeve 174. A scraper 180 is connected to the side of the sleeve 174, and the scraper 180 is fitted with the inner wall of the grinding cylinder 110.

[0029] In this embodiment, the sleeve 174 and the scraper 180 are arranged, and the sleeve 174, the scraper 180 cooperate with the grinding ring 165. When the rotating column 161 rotates, the scraper 180 is driven to rotate and scrape the inner wall of the grinding cylinder 110, thereby avoiding the occurrence of blockage as much as possible, improving the production efficiency, and at the same time, timely scraping the material from the inner wall of the grinding cylinder 110, preventing the material from accumulating and piling up during the grinding process, thereby reducing the occurrence of blockage. This helps to maintain the effect of smooth grinding.

[0030] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0031] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the technical principle of the present invention. These improvements and modifications should also be regarded as the protection scope of the present invention.

Claims

1. A biopharmaceutical grinding device, comprising a grinding cylinder (110) and a feed pipe (140), characterized in that: The feed pipe (140) is installed on the grinding cylinder (110), a grinding assembly (160) is installed inside the grinding cylinder (110), a clamping assembly (190) is installed at the bottom of the grinding cylinder (110), and the grinding assembly (160) is used in conjunction with the grinding cylinder (110).

2. A biopharmaceutical grinding device according to claim 1, characterized in that: The end of the feed pipe (140) is connected to a material storage bowl (141), and the material storage bowl (141) is integrally connected to the top end of the feed pipe (140). The feed pipe (140) is connected to the grinding cylinder (110).

3. A biopharmaceutical grinding device according to claim 1, characterized in that: A plurality of fine material holes (111) are provided on the side of the grinding cylinder (110), and a stirring shovel (112) is connected to the end of the grinding cylinder (110).

4. A biopharmaceutical grinding device according to claim 1, characterized in that: The grinding assembly (160) comprises a rotating column (161) and a spiral disk (162); the rotating column (161) is installed inside the grinding cylinder (110); and the spiral disk (162) is integrally arranged on the outside of the rotating column (161).

5. A biopharmaceutical grinding device according to claim 4, characterized in that: The end of the rotating column (161) is connected to a fixing rod (163), the fixing rod (163) extends to the outside of the grinding cylinder (110), and the end of the fixing rod (163) is sleeved with a rotating handle (164).

6. A biopharmaceutical grinding device according to claim 5, characterized in that: A plurality of grinding rings (165) are sleeved on the outer side of the rotating column (161); the outer wall of the grinding ring (165) is connected to a grinding ball (170); the inner wall of the grinding ring (165) is connected to a grinding tip (171); a notch (172) is provided on the side of the rotating column (161); the notch (172) and the grinding tip (171) are used in an intermittent manner.

7. A biopharmaceutical grinding device according to claim 6, characterized in that: A fixing plug (173) is connected to the end of the rotating column (161), and the fixing plug (173) is engaged with the end of the grinding cylinder (110). A sleeve (174) is connected to the outside of the fixing plug (173), and a material groove (175) is provided on the side of the sleeve (174). A scraper (180) is connected to the side of the sleeve (174), and the scraper (180) is fitted with the inner wall of the grinding cylinder (110).

8. The biopharmaceutical grinding device according to claim 1, characterized in that: The clamping assembly (190) comprises a clamping rod (191) and a threaded bolt (192), wherein the clamping rod (191) is connected to the bottom of the grinding cylinder (110), and the threaded bolt (192) is threadedly connected to the bottom of the clamping rod (191).

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