High-pressure microcapsule filling machine

Abstract

The utility model discloses a high-pressure microcapsule filling machine and relates to the technical field of microcapsule forming devices. A positive electrode connecting wire and a negative electrode connecting wire are arranged on one side of the high-voltage generator; a measuring cup and a magnetic stirrer are arranged on the bottom frame; the magnetic stirrer is arranged at the bottom of the measuring cup; a fixed block is arranged on the bottom frame, a fixed rod is arranged on the fixed block, and a movable block is arranged on the fixed rod in a sliding fit manner. An injector is placed between the arc-shaped plates on the two sides, a needle at the bottom of the injector penetrates through the placing ring to press the injector downwards, the arc-shaped plates are driven by the connecting frames on the two sides to clamp and fix the injector, and injectors of different specifications can be clamped and fixed. Under the action of extrusion of the propeller on the push rod of the injector and electric field force, the solution in the injector drips into the solution in the measuring cup, so that microcapsules with different particle sizes can be selectively prepared according to liquid components, the magnetic stirrer can be dispersed in the generated microcapsule particles in the measuring cup, and finally the microcapsule particles with uniform size and uniform particle size can be formed. The microcapsule is spherical and has a smooth surface.

Description

Technical Field

[0001] The utility model belongs to the field of microcapsule forming devices, in particular to a high-pressure microcapsule filling machine. Background Art

[0002] The existing microcapsule technology uses natural or synthetic polymer materials as microcapsule wall materials to encapsulate solid and liquid pharmaceuticals, foods and chemical raw materials as microcapsule core materials to make micron or nanometer-level particle products. Since its invention in the 1930s, the research and development of microcapsule technology has been rapid, and it has been widely used in various fields: drug delivery, controlling the release rate of drugs, improving their bioavailability, reducing drug toxicity and improving therapeutic effects; food and beverages, used to encapsulate spices, pigments, vitamins, acidulants, etc. to enhance the taste and nutritional value of food; cosmetics, encapsulating spices, moisturizers, antioxidants, etc. to provide long-lasting cosmetic effects and improve product stability; paints and coatings, used to encapsulate pigments, preservatives, plasticizers, etc. to achieve controlled release and extend the service life of coatings, etc.

[0003] Microcapsule wall materials can protect the embedded core material from environmental influences, mask its odor and color, reduce toxicity, prolong the storage time of volatile substances, delay or control the release of core materials, and improve the processability and stability of substances. Microcapsules can be designed into a variety of sizes, shapes and wall materials according to different application requirements to meet different functions and multiple application requirements. At present, the most commonly used microencapsulation devices for bifidobacteria and pancreatic islet cells are sharp-hole extrusion encapsulation devices and airflow encapsulation devices. The microcapsules prepared by these two devices have a larger particle size, and the size uniformity and shape consistency are poor.

[0004] The utility model adopts the sharp hole coagulation method for microencapsulation, and drips the suspension of the core material and the wall material into a solvent such as calcium oxide through a sharp hole device to cause the wall material to undergo a cross-linking reaction. This method is mainly suitable for fat-soluble substances or biologically active substances that are sensitive to ultraviolet light, and the operation is simple. For example, alginate gel particles can be used as a safe and simple carrier, and undergo a gelation reaction with calcium ions under mild conditions, and have been widely used in the embedding and delivery of different proteins or protein enzymes.

[0005] There are many advantages to using high-voltage electric fields to prepare microcapsules: high efficiency, by adjusting the electric field parameters appropriately, microcapsules can be formed in a shorter time, thus improving production efficiency; controllability, by adjusting parameters such as the electric field intensity, frequency and duration, microcapsules with relatively uniform size, round shape, smooth surface and appropriate size can be prepared; scalability, suitable for large-scale production of microcapsules to meet the needs of a large number of products.

[0006] In view of this, the present utility model is proposed. Utility Model Content

[0007] The technical problem to be solved by the utility model is to overcome the deficiencies of the prior art and provide a high-pressure microcapsule encapsulation machine.

[0008] In order to solve the above technical problems, the utility model adopts a technical solution with the following basic ideas:

[0009] A high-voltage microcapsule encapsulation machine comprises a bottom frame, a high-voltage generator is arranged in the bottom frame, a positive electrode connecting line and a negative electrode connecting line are arranged on one side of the high-voltage generator, a measuring cup is arranged on the bottom frame, a magnetic stirrer is arranged at the bottom of the measuring cup, a fixing block is arranged on the bottom frame, a fixing rod is arranged on the fixing block, and a moving block is slidably matched on the fixing rod;

[0010] A clamping assembly is provided on the moving block, and a syringe is provided on the clamping assembly. The needle tube of the syringe is electrically connected to one end of the positive electrode connecting line, and one end of the negative electrode connecting line is located at the bottom of the measuring cup. A propeller is installed on the moving block, and the output shaft of the propeller abuts against the push rod of the syringe.

[0011] Optionally, the clamping assembly includes clamping blocks that are slidably fitted on both sides of the moving block, a placement ring that is slidably fitted on the moving block, and a connecting frame arranged between the two clamping blocks and the placement ring; an arc-shaped plate is installed on one side of the clamping block, a first connecting column is installed on the other side of the clamping block, connecting grooves are opened on opposite sides of the connecting frame, the first connecting column rotatably fits in one of the connecting grooves, a sliding block is installed on one side of the placement ring, second connecting columns are installed on opposite sides of the sliding block, and the second connecting column rotatably fits in the other connecting groove; by placing the syringe between the arc-shaped plates on both sides, the needle at the bottom of the syringe passes through the placement ring to press it down, and the arc-shaped plates are driven by the connecting frames on both sides to clamp and fix the syringe, so syringes of different specifications can be clamped and fixed.

[0012] Optionally, a clamping block is installed on both sides of the slider, a clamping slot is opened on the moving block, the clamping block is located in the clamping slot, a first sliding slot and a second sliding slot are opened on the moving block, the clamping block is slidably fitted in the first sliding slot, and the slider is slidably fitted in the second sliding slot.

[0013] Optionally, an adjusting block is installed on one side of the movable block, and a slot is provided on the adjusting block, and the slot is slidably fitted on the fixed rod. A first through hole and a second through hole are provided on the fixed block, and an adjusting rod is rotatably fitted in the first through hole, and a threaded rod is rotatably fitted in the second through hole. A threaded hole is provided on the adjusting block, and the threaded rod is threadedly fitted in the threaded hole. A limit plate is provided on the fixed rod, and a first bevel gear is provided at one end of the adjusting rod, and a second bevel gear is provided at one end of the threaded rod, and the first bevel gear is meshed with the second bevel gear; the threaded rod is driven to rotate by rotating the adjusting rod, so that rotating the adjusting rod can drive the adjusting block to slide up and down on the fixed rod to adjust the distance between the syringe needle and the liquid level in the measuring cup.

[0014] After adopting the above technical solution, the utility model has the following beneficial effects compared with the prior art. Of course, any product implementing the utility model does not necessarily need to achieve all the advantages described below at the same time:

[0015] 1. The high-pressure microcapsule filling machine places the syringe between the arc plates on both sides, and the needle at the bottom of the syringe passes through the placement ring to press it down. The arc plates are driven by the connecting frames on both sides to clamp and fix the syringe. Syringes of different specifications can be clamped and fixed. A slider is provided on one side of the placement ring, and blocks are installed on both sides of the slider. The blocks are connected to the slots of the moving blocks to limit and fix the slider, ensuring the stability of the arc plates on both sides to clamp syringes of different specifications. Under the action of the pusher squeezing the push rod of the syringe and the electric field force, the solution in the syringe is dripped into the solution in the measuring cup and solidified into micron-level microcapsules with uniform size, spherical shape and smooth surface.

[0016] 2. A magnetic stirrer with adjustable speed is set at the bottom of the measuring cup. The generated microcapsule particles are easily dispersed and will not aggregate through the rotation of the magnetic stirrer in the measuring cup.

[0017] 3. The high-pressure microcapsule filling machine drives the threaded rod to rotate by rotating the adjusting rod. The thread of the adjusting block is matched with the threaded rod, so that the rotating adjusting rod can drive the adjusting block to slide up and down on the fixed rod to adjust the distance between the syringe needle and the liquid level in the measuring cup.

[0018] The specific implementation of the utility model is further described in detail below in conjunction with the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The drawings described below are only some embodiments. For those skilled in the art, other drawings can be obtained based on these drawings without creative work. In the drawings:

[0020] Figure 1 It is a schematic diagram of the overall structure of the embodiment of the utility model;

[0021] Figure 2 This is a schematic diagram of the structure of the adjustment block of the embodiment of the utility model;

[0022] Figure 3 This is a schematic diagram of the exploded structure of the clamping assembly of the embodiment of the utility model;

[0023] Figure 4 This is a schematic structural diagram of the connection between the adjusting rod and the threaded rod in the embodiment of the utility model;

[0024] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0025] 1-bottom frame, 2-high voltage generator, 3-measuring cup, 4-fixed block, 5-fixed rod, 6-moving block, 7-syringe, 8-thruster, 9-positive electrode connecting wire, 10-negative electrode connecting wire, 11-adjusting block, 12-slot hole, 13-threaded hole, 14-first slide groove, 15-second slide groove, 16-card groove, 17-clamping block, 18-connecting frame, 19-placing ring, 20-arc plate, 21-first connecting column, 22-connecting groove, 23-second connecting column, 24-slider, 25-card block, 26-limiting plate, 27-first through hole, 28-second through hole, 29-adjusting rod, 30-threaded rod, 31-second bevel gear, 32-first bevel gear, 33-magnetic stirrer.

[0026] It should be noted that these drawings and textual descriptions are not intended to limit the conceptual scope of the present invention in any way, but rather to illustrate the concept of the present invention for those skilled in the art by referring to specific embodiments. DETAILED DESCRIPTION

[0027] The utility model will now be further described in detail with reference to the accompanying drawings.

[0028] See also Figure 1-4 As shown, in this embodiment, a high-voltage microcapsule encapsulation machine is provided, including a bottom frame 1, a high-voltage generator 2 is arranged in the bottom frame 1, a positive electrode connecting line 9 and a negative electrode connecting line 10 are arranged on one side of the high-voltage generator 2, a measuring cup 3 and a magnetic stirrer 33 are arranged on the bottom frame 1, a fixing block 4 is arranged on the fixing block 4, a fixing rod 5 is arranged on the fixing rod 5, and a moving block 6 is slidably matched on the fixing rod 5;

[0029] The moving block 6 is provided with a clamping assembly, and the clamping assembly is provided with a syringe 7, the needle tube of the syringe 7 is electrically connected to one end of the positive electrode connection line 9, and one end of the negative electrode connection line 10 is located at the bottom of the measuring cup 3. The moving block 6 is provided with a propeller 8, and the output shaft of the propeller 8 abuts against the push rod of the syringe 7. Under the action of the propeller 8 squeezing the push rod of the syringe 7 and the electric field force, the solution in the syringe 7 is dripped into the solution in the measuring cup 3, and solidified into microcapsules with an average particle size of micrometer level, relatively uniform size, spherical shape, and smooth surface. The magnetic stirrer 33 can disperse the microcapsule particles generated in the measuring cup 3. The propeller 8 can be any one of the electric cylinder, electric telescopic rod, and electric spiral telescopic rod in the prior art.

[0030] The clamping assembly of this embodiment includes clamping blocks 17 that are slidably fitted on both sides of the moving block 6, a placement ring 19 that is slidably fitted on the moving block 6, and a connecting frame 18 arranged between the two clamping blocks 17 and the placement ring 19. An arc plate 20 is installed on one side of the clamping block 17, and a first connecting column 21 is installed on the other side of the clamping block 17. Connecting grooves 22 are opened on the opposite sides of the connecting frame 18, and the first connecting column 21 is rotatably fitted in one of the connecting grooves 22. A slider 24 is installed on one side of the placement ring 19, and second connecting columns 23 are installed on the opposite sides of the slider 24. The second connecting column 23 is rotatably fitted in the other connecting groove 22. ; By placing the syringe 7 between the arc-shaped plates 20 on both sides, the needle at the bottom of the syringe 7 passes through the placement ring 19 to press it down, and the arc-shaped plates 20 are driven by the connecting frames 18 on both sides to clamp and fix the syringe 7. Syringes 7 of different specifications can be clamped and fixed. A slider 24 is provided on one side of the placement ring 19, and a clamping block 25 is provided on it. The slider 24 is clamped in the clamping groove 16 of the moving block 6 to limit and fix the slider 24, thereby ensuring the stability of the arc-shaped plates 20 on both sides to clamp syringes 7 of different specifications. The positions of the clamping grooves 16 in this embodiment correspond to the normal diameter of the needle tube in the prior art, which is easy to match.

[0031] In this embodiment, blocks 25 are installed on both sides of the slider 24, a slot 16 is provided on the moving block 6, the block 25 is located in the slot 16, a first slide groove 14 and a second slide groove 15 are provided on the moving block 6, the clamping block 17 is slidably fitted in the first slide groove 14, and the slider 24 is slidably fitted in the second slide groove 15.

[0032] An adjusting block 11 is mounted on one side of the movable block 6 of the present embodiment. A slotted hole 12 is provided on the adjusting block 11. The slotted hole 12 is slidably fitted on the fixed rod 5. A first through hole 27 and a second through hole 28 are provided on the fixed block 4. An adjusting rod 29 is rotatably fitted in the first through hole 27. A threaded rod 30 is rotatably fitted in the second through hole 28. A threaded hole 13 is provided on the adjusting block 11. The threaded rod 30 is fitted in the threaded hole 13. A limiting plate 26 is mounted on the fixed rod 5. A first bevel gear 32 is provided at one end of the adjusting rod 29. A second bevel gear 31 is provided at one end of the threaded rod 30. The first bevel gear 32 is meshed with the second bevel gear 31. The threaded rod 30 is driven to rotate by rotating the adjusting rod 29. The threaded hole 13 of the adjusting block 11 is threadedly fitted on the threaded rod 30. The rotating adjusting rod 29 can drive the adjusting block 11 to slide up and down on the fixed rod 5 to adjust the distance between the needle of the syringe 7 and the liquid level in the measuring cup 3.

[0033] The present invention is not limited to the above-mentioned implementation modes. Anyone should be aware of the structural changes made under the inspiration of the present invention. Any technical solution that is the same or similar to the present invention falls within the protection scope of the present invention. The technology, shape, and structure that are not described in detail in the present invention are all known technologies.

Claims

1. A high pressure microcapsule encapsulation machine, characterized in that: include: A bottom frame (1) is provided inside the bottom frame (1), a positive electrode connecting line (9) and a negative electrode connecting line (10) are provided on one side of the high voltage generator (2), a measuring cup (3) and a magnetic stirrer (33) are provided on the bottom frame (1), a fixing block (4) is provided on the fixing block (4), a fixing rod (5) is provided on the fixing block (4), a moving block (6) is slidably matched on the fixing rod (5), a clamping assembly is provided on the moving block (6), a syringe (7) is provided on the clamping assembly, a needle tube of the syringe (7) is electrically connected to one end of the positive electrode connecting line (9), one end of the negative electrode connecting line (10) is located at the bottom of the measuring cup (3), a propeller (8) is provided on the moving block (6), and an output shaft of the propeller (8) abuts against a push rod of the syringe (7).

2. A high pressure microcapsule encapsulation machine according to claim 1, characterized in that The clamping assembly comprises clamping blocks (17) slidably fitted on both sides of a moving block (6), a placement ring (19) slidably fitted on the moving block (6), and a connecting frame (18) arranged between the two clamping blocks (17) and the placement ring (19); an arc plate (20) is installed on one side of the clamping block (17).

3. A high pressure microcapsule encapsulation machine according to claim 2, characterized in that: A first connecting column (21) is installed on one side of the clamping block (17), and connecting grooves (22) are provided on opposite sides of the connecting frame (18). The first connecting column (21) is rotatably engaged in one of the connecting grooves (22). A sliding block (24) is installed on one side of the placement ring (19), and second connecting columns (23) are installed on opposite sides of the sliding block (24). The second connecting column (23) is rotatably engaged in the other connecting groove (22).

4. A high pressure microcapsule encapsulation machine according to claim 3, characterized in that: A clamping block (25) is installed on both sides of the slider (24); a clamping groove (16) is provided on the moving block (6); the clamping block (25) is located in the clamping groove (16); a first sliding groove (14) and a second sliding groove (15) are provided on the moving block (6); the clamping block (17) is slidably fitted in the first sliding groove (14); and the slider (24) is slidably fitted in the second sliding groove (15).

5. A high pressure microcapsule encapsulation machine according to claim 1, characterized in that: An adjusting block (11) is arranged on one side of the moving block (6), a slot hole (12) is provided on the adjusting block (11), and the slot hole (12) is slidably fitted on the fixing rod (5), a first through hole (27) and a second through hole (28) are provided on the fixing block (4), an adjusting rod (29) is rotatably fitted in the first through hole (27), and a threaded rod (30) is rotatably fitted in the second through hole (28).

6. A high pressure microcapsule encapsulation machine according to claim 5, characterized in that: A threaded hole (13) is provided on the adjusting block (11), a threaded rod (30) is threadedly engaged in the threaded hole (13), a limiting plate (26) is installed on the fixing rod (5), a first bevel gear (32) is installed at one end of the adjusting rod (29), a second bevel gear (31) is installed at one end of the threaded rod (30), and the first bevel gear (32) is meshed with the second bevel gear (31).

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