Ophthalmic instrument experimental animal platform

Abstract

The utility model relates to an ophthalmology instrument experiment animal platform which comprises an ophthalmology equipment adaptation frame and an animal platform body. The ophthalmology equipment adaptive frame comprises a column clamp, an adjusting frame and a base, the column clamp is used for clamping an ophthalmology equipment column, and the base is connected to the bottom of the adjusting frame and used for being supported on an ophthalmology equipment neck support; the animal platform is installed on the adjusting frame, the platform surface of the animal platform is located in the observation view field of the ophthalmology equipment in front of the adjusting frame, and an experimental animal fixing device is arranged on the animal platform; the experimental animal fixing device comprises an animal body fixing structure, a tooth fixing structure and a skull fixing structure to form a three-stage fixing system, so that the experimental animal is fixed and the eyes are still. The ophthalmological instrument experimental animal platform can be matched with common instruments for ophthalmological examination, experimental animals can be conveniently fixed, animal eyeballs are prevented from shaking and the like, the observation angle and distance of the eyeballs of the experimental animals can be accurately adjusted, the consistency of ophthalmological examination operation is guaranteed, and experimental animal imaging scientific research data are accurate.

Description

Technical Field

[0001] The invention relates to the field of animal experimental devices, and in particular to an ophthalmic instrument experimental animal platform. Background Art

[0002] In ophthalmic research, ophthalmic outpatient instrument examinations such as OCT, OCTA (intravascular optical coherence tomography), fundus photography, laser, anterior segment photography, corneal confocal imaging, etc. are often applied to experimental animals, such as mouse experiments or other animal experiments. However, there are some obvious problems to be solved in these ophthalmic examinations. Take mouse experiments as an example:

[0003] 1. Scientific research results need to ensure the consistency of the orientation, angle and distance of mouse photos so that the results can be true and reliable. However, existing outpatient examinations such as mouse OCT lack a platform that can fix and accurately adjust the angle and distance of the mouse eyes, resulting in inconsistent experimental results.

[0004] 2. Mice cannot adjust the direction of their eyeballs like humans, so researchers need to hold the mice and turn them. Novices need to spend a lot of time adjusting the fundus field of the mice. However, the cornea of ​​the mice will gradually become opaque 30 seconds to 1 minute after anesthesia. If the adjustment time is too long, the image will be unclear and the shooting will fail.

[0005] 3. The mouse will shake when held in the hand or placed on a plane. The shaking caused by researchers holding the mouse for too long and the inevitable shaking of the mouse's body due to breathing after anesthesia. In particular, OCTA requires the imaging equipment to remain still for a certain period of time. The shaking will make it impossible to track and focus, resulting in artifacts and French fry-like blood vessels, affecting the reliability of imaging and subsequent data.

[0006] 4. In order to fix the mouse's head, researchers and novices may increase the force to keep the mouse's head still, which may cause the mouse to have difficulty breathing and easily lead to the mouse's death.

[0007] 5. Mouse experiments usually last for several hours, and usually require a researcher to hold the mouse by hand to adjust the observation field of view. Holding the mouse by hand consumes a lot of physical energy and energy of the researcher, and the imaging effect is not good. OCTA, an instrument that requires the mouse's head to remain still, has a high-quality shooting success rate as low as 20%.

[0008] Some technical solutions disclosed in the prior art, such as patent CN217244937U, discloses an animal eye clamp, which is also an instrument for fixing mice during surgical procedures, but cannot be adapted to commonly used instruments for ophthalmic examinations and has low applicability; patent CN202960816U discloses an electrophysiological animal examination platform, which is only suitable for electrophysiological detection and cannot be used for various ophthalmic detection instruments, and only has a flat plate for placing mice, which cannot solve various problems such as mouse eye jitter and eye position adjustment. It is inconvenient to operate and unstable when placed on a desktop or on the ground. Summary of the invention

[0009] The technical problem to be solved by the present invention is to provide an ophthalmic instrument experimental animal platform for the problems in the prior art, which can be adapted to commonly used instruments for ophthalmic examinations, and can also facilitate the fixation of experimental animals and prevent animal eye shaking, etc., and can ensure the consistency and accuracy of fundus imaging photographs of experimental animals.

[0010] To achieve the above purpose, the technical solution provided by the present invention is:

[0011] An ophthalmic instrument experimental animal platform comprises an ophthalmic equipment adapter frame and an animal platform; the ophthalmic equipment adapter frame comprises a column clamp, an adjustment frame and a base, the column clamp comprises a first column clamp connected to the left side of the adjustment frame and a second column clamp connected to the right side of the adjustment frame, which are respectively used to clamp the left and right columns of the ophthalmic equipment; the base is connected to the bottom of the adjustment frame and is used to support the neck support of the ophthalmic equipment; the animal platform is installed on the adjustment frame, the platform surface of the animal platform is located in the observation field of the ophthalmic equipment in front of the adjustment frame, and an experimental animal fixing device is provided on the animal platform; the experimental animal fixing device comprises an animal body fixing structure, a tooth fixing structure and a skull fixing structure, forming a three-level fixing system; wherein the animal body fixing structure is used to fix the experimental animal as a whole on the animal platform, the tooth fixing structure is used to fix the teeth of the experimental animal, and the skull fixing structure is used to fix the head bone of the experimental animal, and the three-level fixing system fixes the experimental animal and achieves eye stillness.

[0012] To optimize the above technical solutions, the specific measures taken also include:

[0013] The adjustment frame has a horizontal support frame, and the column clamp is installed on the support frame through a sliding assembly; the adjustment frame corresponds to the first column clamp on the left and the second column clamp on the right, and is respectively provided with a left support frame and a right support frame, the first column clamp is installed on the left support frame through a first sliding assembly, and the second column clamp is installed on the right support frame through a second sliding assembly.

[0014] Furthermore, the sliding assembly includes a first sliding block with a middle through hole, the support frame passes through the middle through hole of the first sliding block, so that the first sliding block can move horizontally on the support frame, and a first adjusting nut is installed on the side end of the first sliding block, the first adjusting nut passes through the side of the first sliding block, and the end of the first adjusting nut is against the support frame in the middle through hole of the first sliding block, and the first nut is adjusted and tightened to fix the position of the first sliding block on the support frame; the sliding assembly also includes a second sliding block with a middle through hole, the clamp body of the column clamp is connected to the column clamp rod, and the column clamp rod passes through The second sliding block is rotatably connected to the second sliding block by an adjusting column, and one end of the adjusting column is connected to the first sliding block and the other end of the adjusting column is connected to the second sliding block. The adjusting column is rotated to change the angle between the column clamping rod and the support frame.

[0015] Furthermore, the adjustment frame has a vertical mounting frame, the bottom of the mounting frame is connected to the base, the upper part of the mounting frame is connected to the animal platform, and the bottom is supported on the ophthalmic equipment neck support through the base; the mounting frame has a retractable section to adjust the height of the animal platform.

[0016] Furthermore, the adjustment frame is connected to the animal platform via an electric joint assembly.

[0017] As a preferred solution, the electric joint assembly includes a first electric joint, a mechanical arm and a second electric joint, the first electric joint is installed on the upper part of the adjustment frame, the first electric joint is connected to the mechanical arm, the other end of the mechanical arm is connected to the second electric joint, and the animal platform is installed on the second electric joint.

[0018] As a preferred solution, the robotic arm includes a first arm body and a second arm body, one end of the first arm body is installed on the first electric joint, one end of the second arm body is rotatably installed on the other end of the first arm body, and the other end of the second arm body is installed on the second electric joint.

[0019] As a preferred solution, the animal platform is equipped with a lighting system for illuminating the animal platform surface; a heating device is installed at the bottom of the animal platform for heating and insulating the platform surface; the clamp body of the column clamp is a universal clamp; the base is a tray-type base, and the bottom of the tray-type base has a curvature to adapt to the shape of the neck support of the ophthalmic equipment.

[0020] As a preferred solution, the animal body fixing structure is a strap arranged on an animal platform; the teeth fixing structure is a braces assembly; the braces assembly includes a braces seat, a braces cover and a braces; the braces seat is installed on the animal platform, and the braces can be installed on one side of the braces seat so as to move up and down, and a scale line showing the height is provided on the braces seat; the braces cover can be rotatably installed on the braces to open or close the braces; the skull fixing structure is an ear bar assembly, which is used to clamp the depressions on both sides of the skull of the experimental animal; the ear bar assembly includes an ear bar mounting column, an adjustment block and an ear bar; the ear bar mounting column is installed on the animal platform, the adjustment block is sleeved on the ear bar mounting column, a knob is provided on the top of the ear bar mounting column to adjust the height of the adjustment block on the mounting column, an ear bar mounting groove is provided on the adjustment block, and the ear bar is embedded in the ear bar mounting groove.

[0021] As a preferred solution, it also includes a control system, which is connected to the electric joint component signal to control and adjust the orientation or angle of the animal platform through the electric joint component.

[0022] Compared with the prior art, the present invention has the following beneficial effects:

[0023] The ophthalmic instrument experimental animal platform of the present invention can ensure the determination of the eyeball position and observation angle of the experimental animal and absolute stillness, and ensure the consistency of the ophthalmic examination operation, so that the experimental animal imaging research data is accurate, which is crucial to the reliability of the research results.

[0024] The ophthalmic instrument experimental animal platform of the present invention can be adapted to commonly used instruments for ophthalmic examinations, and thus can be used in conjunction with various ophthalmic outpatient equipment to complete animal ophthalmic experiments.

[0025] The ophthalmic instrument experimental animal platform of the present invention can conveniently fix the experimental animals and prevent the animal's eyeballs from shaking.

[0026] The ophthalmic instrument experimental animal platform of the present invention facilitates placing the optic disc in the center of the visual field, which is particularly important for the observation of imaging images, especially OCT and OCTA optic nerve patterns; the visual field can also be adjusted by adjusting the orientation or angle of the animal platform, which facilitates the observation of various angles of the fundus of the experimental animal and achieves the experimental purpose.

[0027] The ophthalmic instrument experimental animal platform of the present invention can smoothly and quickly complete ophthalmic examination experiments, avoiding the problem of high experimental failure rate due to the cornea of ​​the experimental animal becoming opaque due to too long adjustment time; and avoiding the problem of experimental animals being easily killed due to the experimenter needing to pinch the experimental animal with excessive force to fix it.

[0028] The present invention can be equipped with an animal platform heating device to heat and keep the platform surface warm, thereby improving the survival rate of experimental animals.

[0029] The ophthalmic instrument experimental animal platform of the present invention can reduce the physical effort expended by scientific researchers holding the instrument for several hours, thereby saving experimental time, increasing the number of experiments, greatly improving the shooting quality, and improving the data availability and reliability. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 : A schematic structural diagram of the ophthalmic instrument experimental animal platform of the present invention.

[0031] Figure 2 : A schematic diagram of the top view of the ophthalmic instrument experimental animal platform of the present invention.

[0032] Figure 3 : Schematic diagram of the structure of the column clamp part.

[0033] Figure 4 : Schematic diagram of the structure of the ear bar assembly.

[0034] Figure 5 : Schematic diagram of the structure of the braces assembly.

[0035] In the figure: 1-column clamp, 2-adjustment frame, 3-base, 4-first electric joint, 5-second electric joint, 6-illumination system, 7-tooth fixing structure, 8-skull fixing structure, 9-animal body fixing structure, 10-animal platform, 11-control system, 12-support frame, 13-clamp body, 14-tension adjustment knob, 15-second sliding block, 16-adjustment column, 17-first sliding block, 18-ear bar assembly, 19-knob, 20-ear bar, 21-ear bar adjustment knob, 22-adjustment block, 23-braces assembly, 24-braces seat, 25-braces cover, 26-braces, 27-braces height adjustment knob, 28-mounting frame, 29-retractable section, 30-first arm body, 31-second arm body, 32-slider, 33-ear bar mounting column. DETAILED DESCRIPTION

[0036] The above contents of the present invention are further described in detail below in the form of embodiments, but this should not be understood as the scope of the above subject matter of the present invention being limited to the following embodiments, and all technologies realized based on the above contents of the present invention belong to the scope of the present invention.

[0037] In the description of the present invention, it is also necessary to explain:

[0038] The orientation or position relationship is based on the relationship shown in the drawings and is only for the convenience of describing the present invention and simplifying the description. It does not indicate or imply that the device referred to must have a specific orientation, be constructed and operate in a specific orientation. Therefore, it should not be understood as a limitation on the present invention.

[0039] In addition, terms such as "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0040] The present invention provides an ophthalmic instrument experimental animal platform, such as Figure 1 As shown, it includes an ophthalmic equipment adapter frame and an animal platform 10; the ophthalmic equipment adapter frame includes a column clamp 1, an adjustment frame 2 and a base 3, the column clamp 1 includes a first column clamp connected to the left side of the adjustment frame and a second column clamp connected to the right side of the adjustment frame, which are respectively used to clamp the left and right columns of the ophthalmic equipment; the base 3 is connected to the bottom of the adjustment frame and is used to support the neck support of the ophthalmic equipment; the animal platform 10 is installed on the adjustment frame. The platform surface of the animal platform 10 is located in the ophthalmic equipment observation field in front of the adjustment frame.

[0041] In the embodiment, the clamp body of the column clamp 1 is a universal clamp. Since the universal clamp has a tension adjustment knob 14, the distance between the two clamps can be adjusted to change the size of the clamp. The universal clamp is used to facilitate the fixation of ophthalmic instruments of various models. The clamp body of the universal clamp can be made of plastic rubber material, which is suitable for the fixation of columns of various irregular shapes.

[0042] An experimental animal fixing device is provided on the animal platform 10; the experimental animal fixing device includes an animal body fixing structure 9, a tooth fixing structure 7 and a skull fixing structure 8, forming a three-level fixing system; wherein the animal body fixing structure 9 is used to fix the experimental animal as a whole on the animal platform 10, the tooth fixing structure 7 is used to fix the teeth of the experimental animal, and the skull fixing structure 8 is used to fix the bones of the head of the experimental animal. The three-level fixing system fixes the experimental animal and achieves eye stillness, which is convenient for fixing the experimental animal and adding a glass slide to the eye of the experimental animal, so as to facilitate long-term static shooting by ophthalmic examination instruments.

[0043] In the embodiment, the animal platform 10 takes a mouse platform as an example.

[0044] The adjustment frame 2 has a horizontal support frame 12, and the column clamp 1 is installed on the support frame 12 through a sliding assembly. The sliding assembly is used to adjust the distance between the first column clamp 12 on the left and the second column clamp 1 on the right to adapt to ophthalmic instruments of various sizes and types.

[0045] Specifically, the adjustment frame 2 corresponds to the first column clamp 12 on the left and the second column clamp 1 on the right, and is respectively provided with a left support frame 12 and a right support frame 12. The first column clamp 12 is installed on the left support frame 12 through a first sliding component, and the second column clamp 1 is installed on the right support frame 12 through a second sliding component.

[0046] The sliding assembly includes a first sliding block 17 with a central through hole, and the support frame 12 passes through the central through hole of the first sliding block 17, so that the first sliding block 17 can move horizontally on the support frame 12. A first adjusting nut is installed on the side end of the first sliding block 17, and the first adjusting nut passes through the side of the first sliding block 17. The end of the first adjusting nut abuts against the support frame 12 in the central through hole of the first sliding block 17. The first nut is adjusted and tightened to fix the position of the first sliding block 17 on the support frame 12; the sliding assembly also includes a second sliding block 15 with a central through hole, and the clamp body 13 of the column clamp 1 is connected to the column clamp Rod, the column clamp rod passes through the middle through hole of the second sliding block 15, so that the second sliding block 15 can move horizontally on the column clamp rod, and a second adjusting nut is installed on the side end of the second sliding block 15, and the second adjusting nut passes through the side of the second sliding block 15. The end of the second adjusting nut is against the column clamp rod in the middle through hole of the second sliding block 15, and the second nut is adjusted and tightened to fix the position of the second sliding block 15 on the column clamp rod; the first sliding block 17 and the second sliding block 15 are rotatably connected through the adjusting column 16, one end of the adjusting column 16 is connected to the first sliding block 17, and the other end is connected to the second sliding block 15.

[0047] The first sliding block 17 is used to mainly adjust the distance between the two column clamps 1, and the second sliding block 15 is used to fine-tune the distance between the two column clamps 1. The adjusting column 16 rotates to change the angle between the column clamp rod and the support frame 12, so as to facilitate the adjustment of the distance between the animal platform 10 and the equipment shooting system.

[0048] The adjustment frame 2 has a vertical mounting frame 28, the bottom of the mounting frame 28 is connected to the base 3, the upper part of the mounting frame 28 is connected to the animal platform 10, and the bottom is supported on the neck support of the ophthalmic equipment through the base 3. In the embodiment, the base 3 is a tray-type base 3, and the bottom of the tray-type base 3 has a curvature to adapt to the shape of the neck support of the ophthalmic equipment.

[0049] In the embodiment, the lower half of the mounting frame 28 has a telescopic section 29 to adjust the height of the animal platform 10 .

[0050] The adjustment frame 2 is connected to the animal platform 10 through an electric joint assembly. Specifically, the electric joint assembly includes a first electric joint 4, a mechanical arm and a second electric joint 5. The first electric joint 4 is installed on the upper part of the adjustment frame 2. The first electric joint 4 is connected to the mechanical arm. The other end of the mechanical arm is connected to the second electric joint 5. The animal platform 10 is installed on the second electric joint 5.

[0051] The robotic arm includes a first arm body 30 and a second arm body 31 , one end of the first arm body 30 is mounted on the first electric joint 4 , one end of the second arm body 31 is rotatably mounted on the other end of the first arm body 30 , and the other end of the second arm body 31 is mounted on the second electric joint 5 .

[0052] The three-level fixing system fixes the experimental animal on the animal platform 10. In the embodiment, the animal body fixing structure 9 is a strap arranged on the animal platform 10.

[0053] The tooth fixing structure 7 is a brace assembly 23; the brace assembly 23 includes a brace seat 24, a brace cover 25 and a brace 26; the brace seat 24 is mounted on the animal platform 10, and the brace 26 is mounted on one side of the brace seat 24 so as to be movable up and down. A scale line showing the height is provided on the brace seat 24. In the embodiment, the brace is mounted on the side of the brace seat 24 through a slider 32, and a reading scale line is provided on the side of the slider 32 where the slider 32 is connected to the brace seat 24. The reading scale line corresponds to the height of the brace on the slider 32, and the reading scale line of the slider 32 is connected to the scale line showing the height of the brace on the brace seat 24, which can be used to directly read the height of the brace at the corresponding position. The brace cover 25 is rotatably mounted on the brace to open or close the tip of the brace. A groove is provided on the brace to hook the incisors of the experimental animal. In the embodiment, a through hole is provided at the rear of the braces, and a thread is provided in the through hole. A braces height adjustment button 27 is installed on one side of the braces seat 24. The bottom of the braces height adjustment button 27 is installed on the animal platform 10. The upper part of the braces height adjustment button 27 is a vertical rotatable cylinder, which passes upward through the through hole at the rear of the braces. The rotatable cylinder has an external thread matching the internal thread of the through hole. The rotation of the rotatable cylinder causes the whole consisting of the braces and the slider 32 to move up and down along the braces seat 24 to adjust the braces height.

[0054] The skull fixing structure 8 is an ear bar assembly 18, which is used to clamp the depressions on both sides of the skull of the experimental animal; the ear bar assembly 18 includes an ear bar mounting column 33, an adjustment block 22 and an ear bar 20; the ear bar mounting column 33 is installed on the animal platform 10, and the ear bar assembly 18 is in two opposite groups, the adjustment block 22 is sleeved on the ear bar mounting column 33, a knob 19 is provided on the top of the ear bar mounting column 33 to adjust the height of the adjustment block 22 on the mounting column, an ear bar mounting groove is provided on one side of the adjustment block 22, the ear bar is embedded in the ear bar mounting groove, and the two ear bars 20 are arranged oppositely. In the embodiment, the knob 19 is an adjustment nut installed on the top of the ear bar mounting column 33, the upper part of the ear bar mounting column 33 has an external thread corresponding to the adjustment nut, the adjustment block 22 is fixedly connected to the adjustment nut and slidably sleeved with the ear bar mounting column 33, and the adjustment nut rotates and moves up and down to change the height of the adjustment block 22 on the mounting column. An ear bar adjusting button 21 is installed on the ear bar, and a slide groove is provided along the ear bar body. The ear bar adjusting button 21 passes through the slide groove and is fixed on the adjusting block 22. The relative sliding of the ear bar and the ear bar adjusting button 21 can cause the ear bar to produce horizontal displacement along the direction of the bar body to change the distance between the two relative ear bars.

[0055] In the embodiment, the animal platform 10 is installed with a lighting system 6 for illuminating the surface of the animal platform 10, which helps to quickly and conveniently locate the animal's eyes.

[0056] In the embodiment, a heating device is installed at the bottom of the animal platform 10 to heat and keep the platform surface warm, which helps to improve the survival rate of the animal after anesthesia.

[0057] In the embodiment, a control system 11 is also included. The control system 11 is connected to the electric joint component signal to control the orientation or angle of the animal platform 10 through the electric joint component. The control system 11 facilitates the operator to control the tilt, translation, and rotation of the animal platform 10 in the front, back, left, and right directions. The control system 11 in the attached figure is a schematic diagram, and the actual control system 11 will add a power supply system, a remote control system, and a display system.

[0058] The ophthalmic instrument experimental animal platform of the present invention is convenient for researchers to adjust the experimental animal angle to observe and photograph the fundus of the experimental animal in all directions, and is convenient for fundus photography, OCT blood flow photography, laser operation, etc.

[0059] The ophthalmic instrument experimental animal platform of the present invention can be designed in size to adapt to different experimental animals, such as a mouse platform, and can also be replaced by a platform for experimental animals such as rats, rabbits, and ducks.

[0060] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Any technician familiar with the profession, without departing from the scope of the technical solution of the present invention, according to the technical essence of the present invention, any simple modification, equivalent replacement and improvement made to the above embodiment still falls within the protection scope of the technical solution of the present invention.

Claims

1. An ophthalmic instrument experimental animal platform, characterized in that: It comprises an ophthalmic equipment adapter frame and an animal platform; the ophthalmic equipment adapter frame comprises a column clamp, an adjustment frame and a base, the column clamp comprises a first column clamp connected to the left side of the adjustment frame and a second column clamp connected to the right side of the adjustment frame, which are respectively used to clamp the left and right columns of the ophthalmic equipment; the base is installed at the bottom of the adjustment frame and is used to support the neck support of the ophthalmic equipment; the animal platform is installed on the adjustment frame so that the platform surface of the animal platform is located in the observation field of the ophthalmic equipment in front of the adjustment frame; an experimental animal fixing device is arranged on the animal platform; the experimental animal fixing device comprises an animal body fixing structure, a tooth fixing structure and a skull fixing structure, forming a three-level fixing system; wherein the animal body fixing structure is used to fix the experimental animal as a whole on the animal platform, the tooth fixing structure is used to fix the teeth of the experimental animal, and the skull fixing structure is used to fix the head bones of the experimental animal, and the experimental animal is fixed and the eyes are still through the three-level fixing system.

2. The ophthalmic instrument experimental animal platform according to claim 1, characterized in that: The adjustment frame has a horizontal support frame, and the column clamp is installed on the support frame through a sliding assembly; the adjustment frame corresponds to the first column clamp on the left and the second column clamp on the right, and is respectively provided with a left support frame and a right support frame, the first column clamp is installed on the left support frame through a first sliding assembly, and the second column clamp is installed on the right support frame through a second sliding assembly.

3. The ophthalmic instrument experimental animal platform according to claim 2, characterized in that: The sliding assembly includes a first sliding block with a central through hole, the support frame passes through the central through hole of the first sliding block, so that the first sliding block can move horizontally on the support frame, a first adjusting nut is installed on the side end of the first sliding block, the first adjusting nut passes through the side of the first sliding block, the end of the first adjusting nut is against the support frame in the central through hole of the first sliding block, and the first nut is adjusted and tightened to fix the position of the first sliding block on the support frame; the sliding assembly also includes a second sliding block with a central through hole, the clamp body of the column clamp is connected to the column clamp rod, the column clamp rod passes through the central through hole of the second sliding block, so that the second sliding block can move horizontally on the column clamp rod, a second adjusting nut is installed on the side end of the second sliding block, the second adjusting nut passes through the side of the second sliding block, the end of the second adjusting nut is against the column clamp rod in the central through hole of the second sliding block, and the second nut is adjusted and tightened to fix the position of the second sliding block on the column clamp rod; the first sliding block and the second sliding block are rotatably connected through an adjusting column, one end of the adjusting column is connected to the first sliding block, and the other end is connected to the second sliding block, and the adjusting column is rotated to change the angle between the column clamp rod and the support frame.

4. The ophthalmic instrument experimental animal platform according to claim 1, characterized in that: The adjustment frame has a vertical mounting frame, the bottom of the mounting frame is connected to the base, the upper part of the mounting frame is connected to the animal platform, and the bottom is supported on the ophthalmic equipment neck support through the base; the mounting frame has a retractable section to adjust the height of the animal platform.

5. The ophthalmic instrument experimental animal platform according to claim 1, characterized in that: The regulating frame is connected with the animal platform through an electric joint assembly.

6. The ophthalmic instrument experimental animal platform according to claim 5, characterized in that: The electric joint assembly includes a first electric joint, a mechanical arm and a second electric joint. The first electric joint is installed on the upper part of the adjustment frame. The first electric joint is connected to the mechanical arm. The other end of the mechanical arm is connected to the second electric joint. The animal platform is installed on the second electric joint.

7. The ophthalmic instrument experimental animal platform according to claim 6, characterized in that: The mechanical arm comprises a first arm body and a second arm body, one end of the first arm body is mounted on a first electric joint, one end of the second arm body is rotatably mounted on the other end of the first arm body, and the other end of the second arm body is mounted on a second electric joint.

8. The ophthalmic instrument experimental animal platform according to claim 1, characterized in that: The animal platform is equipped with a lighting system for illuminating the animal platform surface; a heating device is installed at the bottom of the animal platform for heating and keeping the platform surface warm; the clamp body of the column clamp is a universal clamp; the base is a tray-type base, and the bottom of the tray-type base has an arc to match the shape of the neck support of the ophthalmic equipment.

9. The ophthalmic instrument experimental animal platform according to claim 1, characterized in that: The animal body fixing structure is a strap arranged on the animal platform; the teeth fixing structure is a braces assembly; the braces assembly includes a braces seat, a braces cover and a braces; the braces seat is installed on the animal platform, and the braces can be installed on one side of the braces seat so as to move up and down, and a scale line showing the height is provided on the braces seat; the braces cover can be rotatably installed on the braces to open or close the braces; the skull fixing structure is an ear bar assembly, which is used to clamp the depressions on both sides of the skull of the experimental animal; the ear bar assembly includes an ear bar mounting column, an adjustment block and an ear bar, and the ear bar assembly is two opposite groups; the ear bar mounting column is installed on the animal platform, the adjustment block is sleeved on the ear bar mounting column, a knob is provided on the top of the ear bar mounting column to adjust the height of the adjustment block on the mounting column, an ear bar mounting groove is provided on the adjustment block, and the ear bar is embedded in the ear bar mounting groove.

10. The ophthalmic instrument experimental animal platform according to claim 5 or 6, characterized in that: It also includes a control system, which is connected to the electric joint component signal to control and adjust the orientation or angle of the animal platform through the electric joint component.

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