Experimental animal ear electrical stimulation fixing device

By designing structures such as clampers and friction stripes, the problem of metal sheets not being firmly fixed on the ears of mice is solved, and more stable electrical stimulation fixation is achieved, ensuring the normal progress of the experiment and the accuracy of the data.

CN222341353UActive Publication Date: 2025-01-14CHONGQING MEDICAL UNIVERSITY +1
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Patent Information

Application Number
CN202420902256.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-28
Publication Date
2025-01-14
Estimated Expiration
2034-04-28

AI Technical Summary

Technical Problem

In the prior art, metal sheets are not firmly fixed on the ears of mice and are prone to fall off, which affects the accuracy of experimental data and the normal progress of the experiment.

Method used

An experimental animal ear electrical stimulation fixing device including a clamper is designed. The clamper consists of two moving parts, and the clamping head is clamped and released through a tightening mechanism, and the clamping head is provided with bumps and concaves. Grooves are used to enhance fixing stability and friction stripes are provided in the conductive clamping area to prevent disengagement.

Benefits of technology

It effectively improves the fixing effect of the metal sheet on the ear, avoids falling, ensures the normal progress of the experiment and the accuracy of the data, and reduces the damage to the ears of mice.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the field of experimental equipment, in particular to an experimental animal ear electrical stimulation fixing device which comprises a metal sheet and a clamp holder. The clamp holder comprises a first movable part and a second movable part, the first movable part and the second movable part are rotationally connected, and a tightening mechanism is arranged at the rotationally connected part; the first movable part and the second movable part are each provided with a clamping head and a handle. The metal sheet is fixedly located on one clamping head, and the metal sheet is opposite to the other clamping head. According to the scheme, the fixing effect of the metal sheet on the ear is improved, and the problem that the metal sheet is prone to falling off from the ear of an animal is solved.
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Description

Technical Field

[0001] The utility model relates to the field of experimental equipment, in particular to an experimental animal ear electrical stimulation fixing device. Background Art

[0002] During the experiment, the animal's concha area needs to be electrically stimulated for scientific research. For example, by electrically stimulating the concha area of ​​mice, the effects of electrical stimulation on the mouse's physiology, behavior, and nervous system can be studied, so as to gain a deeper understanding of the mechanisms and treatments of human diseases.

[0003] When the concha area of ​​mice was electrically stimulated, combined with Figure 1 As shown, a metal sheet 2 (in the prior art, the metal sheet 2 is specifically an iron sheet) and a magnet 3 are fixed on the concha area of ​​a mouse 4, and the iron sheet and the magnet 3 are respectively located on both sides of the ear of the mouse 4, so that the iron sheet is adsorbed on the ear by the magnet 3 under the action of magnetic force, and at the same time, a conductive clip 1 is connected to the iron sheet, and a wire is connected to the conductive clip 1, and one end of the wire away from the conductive clip 1 is electrically connected to a detection instrument, so that when electrical stimulation is performed, the iron sheet, the conductive clip 1 and the wire can conduct electricity, so that the electric needle to the wire, the iron sheet, the conductive clip 1, the ear of the mouse 4 and the tail of the mouse 4 forms a closed loop.

[0004] However, there is an ear between the iron sheet and the magnet 3, and the iron sheet is not directly adsorbed on the magnet 3. The magnet 3 itself is small in size, and the magnetic force between the magnet 3 and the iron sheet is weak. The fixing effect of the iron sheet and the magnet 3 is limited. If you are not careful, the iron sheet can easily fall off the ear and is not easy to find, which will affect the normal progress of the experiment and affect the measurement of the experimental data. Utility Model Content

[0005] The utility model aims to provide an experimental animal ear electrical stimulation fixing device to improve the fixing effect of a metal sheet on the ear and solve the problem that the metal sheet is easy to fall off the animal ear.

[0006] In order to achieve the above-mentioned object, the utility model adopts the following technical scheme: an experimental animal ear electrical stimulation fixing device, including a metal sheet and a clamp;

[0007] The clamp comprises a first movable part and a second movable part, the first movable part and the second movable part are rotatably connected, and a tightening mechanism is provided at the rotatably connected part;

[0008] The first movable part and the second movable part are both provided with a clamping head and a handle; the metal sheet is fixed on one of the clamping heads, and the metal sheet is opposite to the other clamping head.

[0009] The principle and advantage of this scheme are: when electrically stimulating the ear of a mouse, the clamp is clamped on the ear of the mouse. Since the metal sheet is fixed on one of the clamping heads and the metal sheet is opposite to the other clamping head, when the two clamping heads clamp the ear of the mouse, the metal sheet is close to the ear of the mouse, and then the existing conductive clip is clamped on the metal sheet. Since the metal sheet is fixed on the clamping head and the clamp is clamped on the ear, the metal sheet is not easy to fall off, which improves the fixing effect of the metal sheet on the ear, avoids the metal sheet from falling off easily and affecting the normal progress of the experiment, and does not affect the measurement of the experimental data.

[0010] The handle in this solution is used to control the clamp, and control the clamping, closing and opening of the two clamping heads. After the two clamping heads clamp the ears, tighten the tightening mechanism, and the first movable part and the second movable part will not rotate freely, so that the two clamping heads automatically open, ensuring the stability of the two clamping heads clamping the ears. When the two clamping heads need to be removed from the ears, loosen the tightening mechanism, and the first movable part and the second movable part can rotate freely. The experimenter rotates the first movable part and the second movable part by operating the handle to open the two clamping heads, thereby removing the clamp from the ear.

[0011] The clamp in this scheme uses the control of a tightening mechanism to achieve the clamping closure and opening control of the two clamping heads. Compared with the clamps with torsion springs in the prior art, on the one hand, it can avoid the two clamping heads clamping the ears too tightly due to the torsion springs, which may cause the mouse's ear pain to increase. On the other hand, the handle allows the clamping heads to be opened without overcoming the elastic force of the torsion springs, making it easier and more labor-saving to open the clamping heads. The two clamping heads can be opened at a larger angle, making the operation smoother and more convenient.

[0012] Preferably, as an improvement, a convex block is fixed on the side of the other clamping head, and the convex block is opposite to the metal sheet. Thus, the convex block is relatively protruding, and can press the ear, so that the ear fits more closely to the metal sheet, and the metal sheet fits the ear better.

[0013] Preferably, as an improvement, a groove that can be opposite to the bump is provided on the metal sheet. Thus, the groove can cooperate with the bump, and the mouse ear will enter the groove under the pressing action of the bump, further improving the stability of the clamp on the ear, and the clamp is not easy to fall off the ear.

[0014] Preferably, as an improvement, the depth of the groove is 0.5-1 mm. Thus, the depth of the groove will not be too large, and the depth of the groove is relatively shallow, so that the mouse ear will not be greatly deformed and cause pain when entering the groove.

[0015] Preferably, as an improvement, a clamping area for clamping the conductive clip is provided on the side of the metal sheet, and friction stripes are provided on the clamping area. The provision of the friction stripes makes the conductive clip clamped on the metal sheet more stably, and the conductive clip is not easy to detach from the metal sheet, thereby improving the stability of the conductive clip clamped on the metal sheet.

[0016] Preferably, as an improvement, a connecting piece is fixedly connected to both the first movable part and the second movable part; and the two connecting pieces are rotatably connected.

[0017] Thus, the rotational connection of the first movable part and the second movable part is achieved through the rotational connection of the two connecting pieces.

[0018] Preferably, as an improvement, the tightening mechanism includes a fixed shaft and a tightening cap; one end of the fixed shaft is fixedly connected to one of the connecting plates, the other connecting plate is provided with an axial hole, the other end of the fixed shaft passes through the axial hole, and the tightening cap is threadedly connected to the other end of the fixed shaft.

[0019] Therefore, after the tightening cap is tightened, the end of the tightening cap abuts against the connecting piece, so that the two connecting pieces fit tightly together. In this way, under the action of the friction between the tightening cap and the connecting piece and the friction between the two connecting pieces, the first movable part and the second movable part are in a locked state, and the first movable part and the second movable part cannot rotate freely.

[0020] When it is necessary to release the locked state of the first movable part and the second movable part, the tightening cap is loosened and the end of the tightening cap no longer abuts against the connecting piece. At this time, the two connecting pieces will not fit tightly together. At the same time, there is a gap between the end of the tightening cap and the connecting piece, and the first movable part and the second movable part can rotate freely.

[0021] The first movable part and the second movable part can be locked and unlocked by twisting the tightening cap. The tightening mechanism has a simple structure and is easy to operate.

[0022] Preferably, as an improvement, a fixing plate is fixedly connected to one end of the fixing shaft away from the tightening cap, and the fixing plate and the connecting plate are fixedly connected. Thus, the fixing of the fixing shaft and the connecting plate is achieved by fixing the fixing plate and the connecting plate. The setting of the fixing plate facilitates fixing the fixing shaft on the connecting plate.

[0023] Preferably, as an improvement, an elastic layer is fixedly connected to the inner wall of the groove. Thus, the provision of the elastic layer can reduce the compression between the ear and the inner wall of the groove, and reduce the pain of the ear.

[0024] Preferably, as an improvement, the bump is elastic. The bump is elastic and relatively soft, which can reduce the pain caused by the bump pressing on the ear. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a schematic diagram of the structure of electrically stimulating the ear clamp area of ​​mice in the prior art.

[0026] Figure 2 This is a stereoscopic diagram of a device for fixing the ear electrical stimulation of experimental animals according to the present application.

[0027] Figure 3 This is a stereoscopic image from another perspective of a device for fixing the ear electrical stimulation of experimental animals according to the present application.

[0028] Figure 4 A stereogram of a fixed axis. DETAILED DESCRIPTION

[0029] The following is further described in detail through specific implementation methods:

[0030] The figure marks in the drawings of the specification include: conductive clip 1, metal sheet 2, magnet 3, mouse 4, clamping head 5, connecting plate 6, fixed shaft 7, handle 8, groove 9, clamping area 10, tightening cap 11, external thread 12, fixing plate 13, smooth section 14, and protrusion 15.

[0031] Example 1

[0032] Basically as attached Figure 2-Figure 4 Shown: An experimental animal ear electrical stimulation fixing device, including a clamp and a metal sheet 2.

[0033] The clamp in this embodiment includes a first movable part and a second movable part, each of which includes a clamping head 5 and a handle 8, and the clamping head 5 and the handle 8 are integrally formed and fixed. The first movable part and the second movable part can be made of plastic, plastic or silicone. In this way, the first movable part and the second movable part are not made of metal, and the first movable part and the second movable part are not too hard, which can reduce the pain caused by the clamping head 5 clamping on the ear.

[0034] The first movable part and the second movable part in this embodiment are rotatably connected, and the specific rotation method is: the first movable part and the second movable part are both integrally formed with a connecting piece 6, and the two connecting pieces 6 are rotatably connected through a shaft. A tightening mechanism is provided at the rotatably connected part, and the tightening mechanism in this embodiment includes a fixed shaft 7 and a tightening cap 11, an inner wall of the tightening cap 11 is provided with an internal thread, one end of the fixed shaft 7 is provided with an external thread 12, and the other end of the fixed shaft 7 is integrally formed with a fixing piece 13, and the part of the fixed shaft 7 between the fixing piece 13 and the external thread 12 is a smooth section 14.

[0035] Combination Figure 3 As shown, the two connecting pieces 6 are provided with shaft holes, and the fixed shaft 7 is Figure 3 The lower part of the shaft hole passes through the two connecting plates 6 upward, and the fixing plate 13 is connected to the Figure 3The sides of the middle and lower connecting pieces 6 are attached to each other, and the fixing piece 13 is fixedly connected to the lower connecting piece 6. The specific fixing method can be adhesive, screw fixing or welding, so that the fixing shaft 7 and Figure 3 The middle and lower connecting pieces 6 are fixed together. One end of the fixed shaft 7 with an external thread 12 passes through the upper connecting piece 6, and the upper connecting piece 6 and the fixed shaft 7 can rotate relative to each other. The tightening cap 11 is threadedly connected to the end of the fixed shaft 7 with an external thread 12. In this way, by tightening the tightening cap 11, Figure 3 The bottom of the middle tightening cap 11 is tightly pressed on the connecting piece 6, and the two connecting pieces 6 are tightly attached to each other. Figure 3 The bottom of the middle tightening cap 11 is tightly fitted with the connecting piece 6, and the first movable part and the second movable part cannot rotate easily. Figure 3 The bottom of the tightening cap 11 will not be pressed on the connecting piece 6, and the two connecting pieces 6 will not be tightly attached to each other. At the same time, there is a gap between the bottom of the tightening cap 11 and the connecting piece 6, so that the first movable part and the second movable part can be easily rotated. Therefore, by twisting the tightening cap 11, it is possible to control whether the first movable part and the second movable part are locked.

[0036] Combination Figure 2 and Figure 3 As shown, the metal sheet 2 in this embodiment is fixed on one of the clamping heads 5, and the specific fixing position is on the side of one of the clamping heads 5, and the side is opposite to the other clamping head 5, so that the metal sheet 2 and the other clamping head 5 are opposite. The metal sheet 2 and the clamping head 5 can be fixed by bonding or by screws. The side of the metal sheet 2 is provided with a clamping area 10 for clamping the conductive clip 1, and the clamping area 10 is provided with friction stripes. Figure 1 The conductive clip 1 can be clamped on the clamping area 10 of the metal sheet 2, and the friction stripes make it difficult for the conductive clip 1 to fall off the metal sheet 2. In this embodiment, the metal sheet 2 can be an iron sheet or an aluminum sheet, but is not limited thereto, and any conductive sheet can be used.

[0037] The specific implementation process is as follows: anesthetize the mouse, loosen the tightening cap 11, and then move the two handles 8 closer to each other to make the first movable part and the second movable part rotate relative to each other, open the two clamping heads 5, and then place the ear of the mouse 4 between the two clamping heads 5.

[0038] The ends of the two handles 8 are moved away from each other, the first movable part and the second movable part rotate relative to each other, and the two clamping heads 5 approach each other until the two clamping heads 5 clamp the soft ears of the mouse 4. Then, one hand holds the two handles 8, and the other hand tightens the tightening cap 11, the first movable part and the second movable part do not rotate freely, and the two clamping heads 5 are in a state of clamping the ears of the mouse 4.

[0039] In this way, when the ear of the mouse 4 is electrically stimulated, since the metal sheet 2 is fixed on one of the clamping heads 5, the two clamping heads 5 clamp the ear of the mouse 4, so the metal sheet 2 is attached to the ear of the mouse 4, and then the existing conductive clip 1 is clamped on the metal sheet 2. Since the metal sheet 2 is fixed on the clamping head 5, and the clamp is clamped on the ear, the clamp is not easy to fall off, so the metal sheet 2 will not fall off, which improves the fixing effect of the metal sheet 2 on the ear, avoids the falling of the metal sheet 2 and affects the normal progress of the experiment, and does not affect the measurement of the experimental data.

[0040] After the electrical stimulation is completed, the tightening cap 11 is loosened, and the two clamping heads 5 are opened by controlling the handle 8, so that the clamp can be removed from the ear of the mouse 4.

[0041] Example 2

[0042] Combination Figure 2 and Figure 3 As shown, this embodiment is further improved on the basis of embodiment 1, and a protrusion 15 is fixed on the side of the clamping head 5 relative to the metal sheet 2, and the protrusion 15 is opposite to the metal sheet 2. In this embodiment, the protrusion 15 can be fixed by bonding or fixing with screws. The protrusion 15 is elastic, for example, the protrusion 15 is made of rubber material or silicone material. The distance between the end of the protrusion 15 and the side of the clamping head 5 is 0.5-1mm, so that the protrusion 15 is thinner, and when the clamping head 5 clamps the ear, the ear of the mouse 4 will not be greatly deformed due to the protrusion of the protrusion 15, causing great pain. The shape of the protrusion 15 is round.

[0043] The metal sheet 2 is provided with a groove 9 that can be opposite to the bump 15. The shape of the groove 9 is circular, and the depth of the groove 9 is 0.5-1mm. An elastic layer is bonded and fixedly connected to the annular inner wall of the groove 9, and specifically, it can be a sponge layer. In this embodiment, the diameter of the bump 15 is 1cm, and the diameter of the groove 9 is slightly larger than the diameter of the bump 15, for example, 1.2-1.5cm.

[0044] Thus, when the ear of the mouse 4 is clamped, the protrusion 15 can press the ear and press the ear into the groove 9, further improving the stability of the clamp on the ear and improving the fixing effect of the clamp. At the same time, the protrusion 15 in this embodiment is relatively soft, and an elastic layer is provided in the groove 9, and the thickness of the protrusion 15 is relatively thin, so that the protrusion 15 presses the ear into the groove 9 without causing obvious pain, thereby avoiding obvious pain in the ear of the mouse 4 and causing the mouse 4 to move violently, and ensuring the stable and normal progress of the experiment.

[0045] Example 3

[0046] In order to improve the firmness of the two connecting pieces 6 when they are pressed together, friction particles are provided on the opposite sides of the two connecting pieces 6. The setting of the friction particles makes the friction between the two connecting pieces 6 greater after the two connecting pieces 6 are pressed together, and the two connecting pieces 6 are not prone to relative movement, making the clamp more firm and stable when locked.

[0047] The above is only an embodiment of the utility model, and the common knowledge such as the known specific technical solutions and / or characteristics in the solution is not described in detail here. It should be pointed out that for those skilled in the art, without departing from the technical solution of the utility model, several deformations and improvements can be made, which should also be regarded as the protection scope of the utility model, and these will not affect the effect of the implementation of the utility model and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. An experimental animal ear electrical stimulation fixture, comprising a metal sheet, characterized in that: Also included is a holder; The clamp comprises a first movable part and a second movable part, the first movable part and the second movable part are rotatably connected, and a tightening mechanism is provided at the rotatably connected part; The first movable part and the second movable part are both provided with a clamping head and a handle; the metal sheet is fixed on one of the clamping heads, and the metal sheet is opposite to the other clamping head.

2. The device for fixing the ear electrical stimulation of an experimental animal according to claim 1, characterized in that: A convex block is fixed on the side surface of the other clamping head, and the convex block is opposite to the metal sheet.

3. The device for fixing the ear electrical stimulation of experimental animals according to claim 2, characterized in that: The metal sheet is provided with a groove which can be opposite to the convex block.

4. The device for fixing the ear electrical stimulation of experimental animals according to claim 3, characterized in that: The depth of the groove is 0.5-1 mm.

5. The device for fixing the ear electrical stimulation of experimental animals according to claim 1, characterized in that: A clamping area for clamping the conductive clip is provided on the side surface of the metal sheet, and friction stripes are provided on the clamping area.

6. The device for fixing the ear electrical stimulation of experimental animals according to claim 1, characterized in that: The first movable part and the second movable part are both fixedly connected with connecting pieces; the two connecting pieces are rotatably connected.

7. The device for fixing the ear electrical stimulation of experimental animals according to claim 6, characterized in that: The tightening mechanism includes a fixed shaft and a tightening cap; one end of the fixed shaft is fixedly connected to one of the connecting pieces, and the other connecting piece is provided with an axial hole, the other end of the fixed shaft passes through the axial hole, and the tightening cap is threadedly connected to the other end of the fixed shaft.

8. The device for fixing the ear electrical stimulation of experimental animals according to claim 7, characterized in that: One end of the fixed shaft away from the tightening cap is fixedly connected with a fixing plate, and the fixing plate is fixedly connected to the connecting plate.

9. The device for fixing the ear electrical stimulation of experimental animals according to claim 3, characterized in that: The inner wall of the groove is fixedly connected with an elastic layer.

10. The device for fixing the ear electrical stimulation of experimental animals according to claim 2, characterized in that: The protrusion is elastic.

Citation Information

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