Polypeptide purification equipment

Abstract

The utility model discloses polypeptide purification equipment which comprises a base, a bracket, a liquid supply pipe, a drying box and a purification structure, the drying box is installed on the base, the liquid supply pipe is installed on the drying box, the support is installed on the base, and the purification structure is installed on the support. The storage structure comprises a drying assembly, a cleaning assembly and a taking assembly. The drying assembly is installed on the drying box, the cleaning assembly is installed on the support, and the taking assembly is installed on the drying box. The utility model relates to the technical field of polypeptide purification, and has the beneficial effects that the heating and drying functions are realized, a polypeptide solution can be dried and purified, the purification efficiency is improved, and the purity of polypeptide is higher; the rotary scraping function is achieved, polypeptide crystals cannot be left in the box wall, and the polypeptide purification effect is better; the equipment can discharge polypeptide crystals more smoothly, and the waiting time is shorter.

Description

Technical Field

[0001] The utility model relates to the technical field of polypeptide purification, in particular to polypeptide purification equipment. Background Art

[0002] Polypeptide is a compound formed by α-amino acids linked together by peptide bonds. It is an intermediate product of protein hydrolysis. The compound formed by the dehydration condensation of two amino acid molecules is called a dipeptide. Similarly, there are tripeptides, tetrapeptides, pentapeptides, etc. Usually, the compound formed by the dehydration condensation of 10-100 amino acid molecules is called a polypeptide.

[0003] The existing patent number is: CN218539567U A polypeptide preparation and purification device, specifically discloses a polypeptide preparation and purification device, belonging to the technical field of polypeptide preparation. The utility model includes a shell, a feed pipe, a discharge valve, an auxiliary frame and a selective permeable membrane. The right end of the shell is respectively connected to the feed pipe and the left end of the discharge valve. The feed pipe is located at the top of the discharge valve. The interior of the shell is respectively fixedly connected to the auxiliary frame and the surface of the selective permeable membrane. The auxiliary frame is located at the top of the selective permeable membrane. The top of the shell is fixedly connected with a piston cylinder. The output end of the piston cylinder extends to the inside of the shell and is fixedly connected with an auxiliary plate. The top of the auxiliary plate is fixedly connected with a motor located outside the piston cylinder. The utility model prevents the mixed solution that has not reacted well from passing through the selective permeable membrane by arranging a piston cylinder, an auxiliary plate, a sealing cover and an auxiliary frame, and uses a motor and a stirring rod to mix the protein base liquid and the reaction solution, thereby accelerating the reaction speed and improving the production efficiency of the purification equipment.

[0004] However, the above patent document also has the following problem: the extracted polypeptide crystals are easily attached to the tank wall, making it inconvenient to take. For the above problem, there may already be technical means to solve it in the prior art, but this case wants to provide an alternative or replacement technical solution, so we designed a polypeptide purification device. Utility Model Content

[0005] To achieve the above objectives, the utility model is implemented through the following technical solutions: a polypeptide purification device, comprising: a base, a bracket, a liquid supply pipe, a drying box and a purification structure; the drying box is installed on the base, the liquid supply pipe is installed on the drying box, the bracket is installed on the base, and the purification structure is installed on the bracket;

[0006] The storage structure includes: a drying component, a cleaning component and a taking component;

[0007] The drying component is installed on the drying box, the cleaning component is installed on the bracket, and the picking component is installed on the drying box;

[0008] The drying component includes: a control valve, a water level gauge, a controller, and a heating wire;

[0009] The liquid inlet pipe is installed at the top of the drying box, the control valve is installed on the liquid inlet pipe, the water level meter is installed inside the drying box, the controller is installed outside the drying box, and the heating wire is installed inside the drying box.

[0010] Preferably, a heat-insulating layer is provided outside the drying box.

[0011] Preferably, the cleaning assembly comprises: a telescopic cylinder, a motor, a support frame, a connecting shaft, and a scraper;

[0012] The telescopic cylinder is installed on the top of the bracket, the support frame is installed on the moving end of the telescopic cylinder, the motor is installed at the center of the support frame, the connecting shaft is installed on the support frame and connected to the output end of the motor, and the scraper is installed on the connecting shaft.

[0013] Preferably, a reinforcement rod is provided at the connection between the connecting shaft and the scraper.

[0014] Preferably, the taking assembly comprises: a mounting frame, a shielding plate, and an electric telescopic rod;

[0015] The mounting frame is mounted on the outside of the drying box, the electric telescopic rod is mounted on the mounting frame, and the shielding plate is mounted on the electric telescopic rod.

[0016] Preferably, the mounting frame is provided with a slide groove having the same size as that of the shielding plate. Beneficial Effects

[0017] The utility model provides a polypeptide purification device, which has the following beneficial effects compared with the existing technical means:

[0018] 1. A drying component is provided. Through the cooperation of the control valve, the water level gauge, the controller and the heating wire, the equipment has the function of heating and drying, and can dry and purify the polypeptide solution, thereby improving the purification efficiency and making the polypeptide purity higher;

[0019] 2. A cleaning component is provided. Through the cooperation of the telescopic cylinder, the motor, the support frame, the connecting shaft and the scraper, the equipment has the function of rotating the scraper, so that no polypeptide crystals remain in the box wall, and the polypeptide purification effect is better;

[0020] 3. A taking component is provided, and through the cooperation of the mounting frame, the shielding plate and the electric telescopic rod, the equipment can discharge the polypeptide crystals more smoothly and the waiting time is shorter. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a schematic diagram of the main structure of a polypeptide purification device of the utility model.

[0022] Figure 2The utility model is a schematic diagram of the side structure of a polypeptide purification device.

[0023] Figure 3 The utility model is a schematic diagram of the three-dimensional structure of a taking component of a polypeptide purification device.

[0024] In the figure: 1. base; 2. bracket; 3. liquid supply pipe; 4. drying box; 5. control valve; 6. water level gauge; 7. controller; 8. heating wire; 9. telescopic cylinder; 10. motor; 11. support frame; 12. connecting shaft; 13. scraper; 14. mounting frame; 15. shielding plate; 16. electric telescopic rod. DETAILED DESCRIPTION

[0025] Based on the embodiments of the present utility model, all other embodiments obtained by ordinary technicians in the field without making any creative work shall fall within the scope of protection of the present utility model.

[0026] See also Figure 1-3 , the utility model provides a technical solution.

[0027] Embodiment 1:

[0028] Please see attached Figure 1-3 In the specific implementation process: a polypeptide purification device includes: a base, a bracket, a liquid supply pipe, a drying box and a purification structure; the drying box is installed on the base, the liquid supply pipe is installed on the drying box, the bracket is installed on the base, and the purification structure is installed on the bracket;

[0029] The storage structure includes: a drying component, a cleaning component and a taking component;

[0030] The drying component is installed on the drying box, the cleaning component is installed on the bracket, and the picking component is installed on the drying box;

[0031] It should be noted that after the polypeptide is melted in water, a polypeptide solution is formed, and the polypeptide solution is injected into a drying box installed on the base through a liquid inlet pipe. The polypeptide solution in the drying box is detected by a water level meter installed in the drying box. When the polypeptide solution is sufficient, the water level meter transmits a signal to a controller installed in the drying box, and the control cabinet valve installed on the liquid inlet pipe is closed by the controller, and the heating wire installed in the drying box is started to dry and purify the polypeptide solution inside.

[0032] After the equipment has finished drying, the telescopic cylinder installed on the top of the bracket is started. Under the action of the telescopic cylinder, the support frame installed on the moving end of the telescopic cylinder is driven to move downward, and the motor installed at the center of the support frame is started. Under the action of the motor, the connecting shaft is driven to rotate, so that the scraper installed on the connecting shaft rotates to scrape the wall of the drying box, and the polypeptide crystals condensed on the wall of the box are scraped off, and the polypeptide crystals are separated and accumulated in the drying box, so that the polypeptide purification effect is better;

[0033] After completing the cleaning of the inner wall of the drying box, open the electric telescopic rod on the mounting bracket installed at the upper end of the discharge port of the A Zi drying box. Under the action of the electric telescopic rod, the shielding plate installed at the moving end of the electric telescopic rod is driven to rise, so that the polypeptide crystals accumulated at the bottom of the drying box are discharged from the box under the action of gravity. At the same time, the cleaning component continues to work, making the discharge of the polypeptide crystals smoother.

[0034] It should be noted that an insulation layer is provided outside the drying box to prevent excessive temperature loss; a reinforcement rod is provided at the connection between the connecting shaft and the scraper to prevent deformation of the scraper; and a slide groove with the same size as the baffle is provided on the mounting frame to facilitate the movement of the baffle.

[0035] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A polypeptide purification device, comprising: Base, bracket, liquid supply pipe, drying box and purification structure; The drying box is installed on the base, the liquid supply pipe is installed on the drying box, the bracket is installed on the base, and the purification structure is installed on the bracket; The storage structure includes: a drying component, a cleaning component and a taking component; The invention is characterized in that the drying component is installed on the drying box, the cleaning component is installed on the bracket, and the taking component is installed on the drying box; The drying component includes: a control valve, a water level gauge, a controller, and a heating wire; The liquid inlet pipe is installed at the top of the drying box, the control valve is installed on the liquid inlet pipe, the water level meter is installed inside the drying box, the controller is installed outside the drying box, and the heating wire is installed inside the drying box.

2. A polypeptide purification device according to claim 1, characterized in that: A heat-insulating layer is arranged outside the drying box.

3. A polypeptide purification device according to claim 1, characterized in that: The cleaning assembly comprises: a telescopic cylinder, a motor, a support frame, a connecting shaft, and a scraper; The telescopic cylinder is installed on the top of the bracket, the support frame is installed on the moving end of the telescopic cylinder, the motor is installed at the center of the support frame, the connecting shaft is installed on the support frame and connected to the output end of the motor, and the scraper is installed on the connecting shaft.

4. A polypeptide purification device according to claim 3, characterized in that: A reinforcing rod is arranged at the connection point between the connecting shaft and the scraper.

5. A polypeptide purification device according to claim 1, characterized in that: The taking assembly comprises: a mounting frame, a shielding plate, and an electric telescopic rod; The mounting frame is mounted on the outside of the drying box, the electric telescopic rod is mounted on the mounting frame, and the shielding plate is mounted on the electric telescopic rod.

6. A polypeptide purification device according to claim 5, characterized in that: The mounting frame is provided with a slide groove having the same size as that of the shielding plate.

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