Hyaluronic acid cross-linking reaction device

Abstract

The utility model discloses a hyaluronic acid cross-linking reaction device, which relates to the technical field of hyaluronic acid reaction and comprises a reaction box, a controller mounted on the front side of the reaction box, a feeding pipe arranged on the upper surface of the reaction box, a blanking hopper mounted on the upper surface of the feeding pipe and a first motor mounted on the upper surface of the reaction box, a first motor is arranged on the lower surface of the reaction box, a first rotating shaft is fixedly connected to the output end of the first motor, the first rotating shaft penetrates through the feeding pipe, a fixing rod is rotatably connected to the surface of the rotating sleeve through a bearing, and a stirring rod is fixedly connected to the surface of the fixing rod. Through the arrangement of the first motor, the first rotating shaft and the rotating rod, the purpose of preventing materials from being blocked is achieved, and through the arrangement of the second rotating shaft, the first bevel gear, the rotating sleeve, the fixed rod, the second bevel gear and the stirring rod, the purpose of improving the reaction effect is achieved.

Description

Technical Field

[0001] The utility model relates to the technical field of hyaluronic acid reaction, in particular to a hyaluronic acid cross-linking reaction device. Background Art

[0002] Cross-linked sodium hyaluronate gel has good physical and chemical properties and biocompatibility. The cross-linked sodium hyaluronate gel is prepared by cross-linking sodium hyaluronate with a chemical cross-linking agent. The chemical cross-linking agent is mixed with sodium hyaluronate and a solvent to form a loose reactant containing a large number of bubbles, which affects the cross-linking reaction.

[0003] A hyaluronic acid cross-linking reaction device is disclosed in the Chinese utility model patent application disclosure CN220634326U. Although the utility model has a simple structure and stirs the hyaluronic acid cross-linking reactant to make the hyaluronic acid cross-linking reactant react evenly, the inner wall of the reaction cylinder can be cleaned to prevent the material from sticking to the inner wall of the reaction cylinder, but the stirring is only performed by a stirring rod, which cannot make the hyaluronic acid cross-linking reactant react evenly, and there is a disadvantage of poor reaction effect. In addition, during the feeding process, the raw material is easy to block the re-feeding port, and there is a disadvantage of easy clogging during feeding. Utility Model Content

[0004] 1. Technical issues to be resolved

[0005] In view of the deficiencies in the prior art, the utility model provides a hyaluronic acid cross-linking reaction device, which solves the problems raised in the above-mentioned background technology.

[0006] (II) Technical solution

[0007] In order to achieve the above objectives, the present invention is implemented through the following technical solutions:

[0008] A hyaluronic acid cross-linking reaction device comprises a reaction box, the lower surface of which is fixedly connected to a support leg, a controller is installed on the front of the reaction box, a feed pipe is provided on the upper surface of the reaction box, a lower hopper is installed on the upper surface of the feed pipe, a first motor is installed on the upper surface of the reaction box, a first rotating shaft is fixedly connected to the output end of the first motor, the first rotating shaft passes through the feed pipe, a rotating rod is fixedly connected to the surface of the first rotating shaft, a second servo motor is installed on the upper surface of the reaction box, a second rotating shaft is fixedly connected to the output end of the second servo motor, the inner surface of the reaction box is rotatably connected to a rotating sleeve through a bearing, the surface of the rotating sleeve is rotatably connected to a fixed rod through a bearing, the surface of the fixed rod is fixedly connected to a stirring rod, a lower surface of the reaction box is provided with a lower pipe, and a discharge valve is installed on the surface of the lower pipe.

[0009] Optionally, a bearing is provided at the connection between the first rotating shaft and the feed pipe, and the number of the rotating rods is two and they are symmetrically distributed.

[0010] Optionally, a first bevel gear is fixedly connected to the surface of the second rotating shaft, a second bevel gear is meshed and transmitted on the surface of the first bevel gear, and the second bevel gear is fixedly connected to the inner end surface of the fixed rod.

[0011] Optionally, a third servo motor is installed on the upper surface of the reaction box, the output end of the third servo motor passes through the top surface of the reaction box and a bearing is provided at the penetration point, the output end of the third servo motor is fixedly connected to the second gear, the surface of the second gear is meshed with the first gear, and the outer surface of the upper part of the rotating sleeve is fixedly connected to the first gear.

[0012] Optionally, the number of the first bevel gear, the fixed rod and the second bevel gear are two each, and they are staggeredly distributed around the second rotating shaft, and each fixed rod has six stirring rods on its surface.

[0013] Optionally, a heating plate is installed on the inner side of the reaction box, a temperature sensor is installed on the surface of the heating plate, and the heating plate and the temperature sensor are electrically connected to the controller through wires respectively.

[0014] (III) Beneficial effects

[0015] The utility model provides a hyaluronic acid cross-linking reaction device, which has the following beneficial effects:

[0016] 1. The hyaluronic acid cross-linking reaction device has the effect of avoiding blockage during the material discharge process through the arrangement of the first motor, the first rotating shaft and the rotating rod. When in use, the raw material enters the reaction box through the material discharge hopper. During the entry process, the first motor is turned on, and the first rotating shaft and the rotating rod are driven to rotate by the first motor, so that the rotating rod rotates under the material discharge hopper to prevent the material from being discharged too quickly and being blocked in the material discharge hopper and the first motor, thereby achieving the purpose of avoiding material blockage.

[0017] 2. The hyaluronic acid cross-linking reaction device has a better uniform reaction effect through the arrangement of the second rotating shaft, the first bevel gear, the rotating sleeve, the fixed rod, the second bevel gear and the stirring rod. When in use, after the raw material enters the reaction box through the feed pipe, the reaction box is heated by the heating plate. Under the action of the temperature sensor, the temperature in the reaction box is monitored, and the monitoring data is sent to the controller, which adjusts the heating temperature of the heating plate to provide the temperature required for the reaction. By turning on the second servo motor and the third servo motor, the second rotating shaft is driven to rotate by the second servo motor, the second rotating shaft drives the first bevel gear, the first bevel gear drives the second bevel gear, and the second bevel gear drives the fixed rod, so that the fixed rod rotates on the surface of the rotating sleeve, and then the stirring rod on the surface of the fixed rod rotates, the second gear is driven to rotate by the third servo motor, the second gear drives the first gear, and the first gear drives the rotating sleeve, so that the fixed rod rotates around the second rotating shaft, and then the stirring rod rotates in multiple directions, which has a better stirring effect. At the same time, with the appropriate reaction temperature, the purpose of improving the reaction effect is achieved. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0019] Figure 2 It is a schematic diagram of the structure of the front section of the utility model;

[0020] Figure 3 For this utility model Figure 2 The structural diagram at A in the middle;

[0021] Figure 4 For this utility model Figure 2 Schematic diagram of the structure at B in the figure.

[0022] In the figure: 1. reaction box; 2. support leg; 3. controller; 4. feed pipe; 5. discharge hopper; 6. first motor; 7. first rotating shaft; 8. rotating rod; 9. heating plate; 10. temperature sensor; 11. second servo motor; 12. second rotating shaft; 13. first bevel gear; 14. rotating sleeve; 15. first gear; 16. third servo motor; 17. second gear; 18. fixing rod; 19. second bevel gear; 20. stirring rod; 21. discharge pipe; 22. discharge valve. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0024] Example 1

[0025] See also Figures 1 to 3 The utility model provides a technical solution: a hyaluronic acid cross-linking reaction device, including a reaction box 1, a supporting leg 2 is fixedly connected to the lower surface of the reaction box 1, a controller 3 is installed on the front of the reaction box 1, a feeding pipe 4 is arranged on the upper surface of the reaction box 1, a lower hopper 5 is installed on the upper surface of the feeding pipe 4, a first motor 6 is installed on the upper surface of the reaction box 1, a first rotating shaft 7 is fixedly connected to the output end of the first motor 6, the first rotating shaft 7 passes through the feeding pipe 4, a rotating rod 8 is fixedly connected to the surface of the first rotating shaft 7, a bearing is arranged at the connection between the first rotating shaft 7 and the feeding pipe 4, and the number of the rotating rods 8 is two, and they are symmetrically distributed.

[0026] In order to avoid material blockage, when in use, the raw material enters the reaction box 1 through the lower hopper 5. During the entry process, the first motor 6 is turned on, and the first motor 6 drives the first rotating shaft 7 and the rotating rod 8 to rotate, so that the rotating rod 8 rotates under the lower hopper 5 to prevent the material from being discharged too quickly and causing the material to be blocked at the lower hopper 5 and the first motor 6, thereby achieving the purpose of avoiding material blockage.

[0027] Example 2

[0028] See also Figure 1 , Figure 2 and Figure 4 The utility model provides a technical solution: a hyaluronic acid cross-linking reaction device, comprising a reaction box 1, a second servo motor 11 is installed on the upper surface of the reaction box 1, and a second rotating shaft 12 is fixedly connected to the output end of the second servo motor 11, and a rotating sleeve 14 is rotatably connected to the inner surface of the reaction box 1 through a bearing, and a fixed rod 18 is rotatably connected to the surface of the rotating sleeve 14 through a bearing, and a stirring rod 20 is fixedly connected to the surface of the fixed rod 18. A discharge pipe 21 is arranged on the lower surface of the reaction box 1, and a discharge valve 22 is installed on the surface of the discharge pipe 21, a first bevel gear 13 is fixedly connected to the surface of the second rotating shaft 12, and a second bevel gear 19 is meshed and driven on the surface of the first bevel gear 13, and the inner end surface of the fixed rod 18 is fixedly connected to the second bevel gear 19, and the reaction A third servo motor 16 is installed on the upper surface of the reaction box 1, and the output end of the third servo motor 16 passes through the top surface of the reaction box 1 and a bearing is provided at the penetration point. The output end of the third servo motor 16 is fixedly connected to the second gear 17, and the surface of the second gear 17 is meshed and transmitted with the first gear 15. The outer surface of the upper part of the rotating sleeve 14 is fixedly connected to the first gear 15. The number of the first bevel gear 13, the fixed rod 18 and the second bevel gear 19 are two, and they are staggered around the second rotating shaft 12. There are six stirring rods 20 on the surface of each fixed rod 18. A heating plate 9 is installed on the inner side of the reaction box 1, and a temperature sensor 10 is installed on the surface of the heating plate 9. The heating plate 9 and the temperature sensor 10 are electrically connected to the controller 3 through wires respectively.

[0029] In order to achieve the purpose of improving the reaction effect, when in use, after the raw material enters the reaction box 1 through the feed pipe 4, the reaction box 1 is heated by the heating plate 9. Under the action of the temperature sensor 10, the temperature in the reaction box 1 is monitored, and the monitoring data is sent to the controller 3. The controller 3 adjusts the heating temperature of the heating plate 9 to provide the temperature required for the reaction. By turning on the second servo motor 11 and the third servo motor 16, the second servo motor 11 drives the second shaft 12 to rotate, and the second shaft 12 drives the first bevel gear 13, and the first bevel gear 13 Then it drives the second bevel gear 19, and the second bevel gear 19 drives the fixed rod 18, so that the fixed rod 18 rotates on the surface of the rotating sleeve 14, and then the stirring rod 20 on the surface of the fixed rod 18 rotates, and the second gear 17 is driven to rotate by the third servo motor 16, and the second gear 17 drives the first gear 15, and the first gear 15 drives the rotating sleeve 14, so that the fixed rod 18 rotates around the second rotating shaft 12, and then the stirring rod 20 rotates in multiple directions, which has a better stirring effect. At the same time, with a suitable reaction temperature, the purpose of improving the reaction effect is achieved.

[0030] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A hyaluronic acid cross-linking reaction device, comprising a reaction box (1), characterized in that: The lower surface of the reaction box (1) is fixedly connected to a support leg (2); a controller (3) is installed on the front of the reaction box (1); a feed pipe (4) is provided on the upper surface of the reaction box (1); a lower hopper (5) is installed on the upper surface of the feed pipe (4); a first motor (6) is installed on the upper surface of the reaction box (1); an output end of the first motor (6) is fixedly connected to a first rotating shaft (7); the first rotating shaft (7) passes through the feed pipe (4); a rotating rod (8) is fixedly connected to the surface of the first rotating shaft (7); A second servo motor (11) is mounted on the upper surface of the reaction box (1); the output end of the second servo motor (11) is fixedly connected to a second rotating shaft (12); the inner surface of the reaction box (1) is rotatably connected to a rotating sleeve (14) via a bearing; the surface of the rotating sleeve (14) is rotatably connected to a fixed rod (18) via a bearing; the surface of the fixed rod (18) is fixedly connected to a stirring rod (20); a discharge pipe (21) is arranged on the lower surface of the reaction box (1); a discharge valve (22) is mounted on the surface of the discharge pipe (21).

2. A hyaluronic acid cross-linking reaction device according to claim 1, characterized in that: A bearing is provided at the connection between the first rotating shaft (7) and the feed pipe (4), and there are two rotating rods (8) which are symmetrically distributed.

3. A hyaluronic acid cross-linking reaction device according to claim 1, characterized in that: The surface of the second rotating shaft (12) is fixedly connected to a first bevel gear (13), the surface of the first bevel gear (13) is meshed with a second bevel gear (19), and the inner end surface of the fixed rod (18) is fixedly connected to the second bevel gear (19).

4. A hyaluronic acid cross-linking reaction device according to claim 1, characterized in that: A third servo motor (16) is mounted on the upper surface of the reaction box (1); the output end of the third servo motor (16) penetrates the top surface of the reaction box (1) and a bearing is provided at the penetration point; the output end of the third servo motor (16) is fixedly connected to a second gear (17); the surface of the second gear (17) is meshed with the first gear (15); and the outer surface of the upper portion of the rotating sleeve (14) is fixedly connected to the first gear (15).

5. A hyaluronic acid cross-linking reaction device according to claim 3, characterized in that: The number of the first bevel gear (13), the fixed rod (18) and the second bevel gear (19) is two each, and they are staggeredly distributed around the second rotating shaft (12), and each fixed rod (18) has six stirring rods (20) on its surface.

6. A hyaluronic acid cross-linking reaction device according to claim 1, characterized in that: A heating plate (9) is installed on the inner side of the reaction box (1), a temperature sensor (10) is installed on the surface of the heating plate (9), and the heating plate (9) and the temperature sensor (10) are electrically connected to the controller (3) via wires.

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