Sample adding device of mycoplasma analysis system

Abstract

The utility model discloses a sample adding device of a mycoplasma analysis system, which comprises a machine table and a sample adding mechanism, and a culture box station for limiting a culture box is arranged on the machine table; the sample adding mechanism comprises a moving frame arranged on the machine table, the moving frame can move in the front-back direction and the left-right direction, a liftable liquid suction assembly and an oil suction assembly are arranged on the moving frame, the lower end of the liquid suction assembly is used for being in butt joint with a liquid suction head, and the liquid suction head is used for sucking sample liquid and injecting the sample liquid into culture holes of a culture box. The lower end of the oil suction assembly is used for being in butt joint with an oil suction head, and the oil suction head is used for sucking paraffin oil and injecting the paraffin oil into the culture holes of the culture box. When the movable frame continuously works, the sample liquid and the paraffin oil can be injected into one culture hole by moving the movable frame back and forth once until the sample adding work is finished, so that the sample adding efficiency can be effectively improved.

Description

Technical Field

[0001] The utility model relates to the technical field of microbial analysis, in particular to a sample adding device of a mycoplasma analysis system. Background Art

[0002] Mycoplasma is a prokaryotic microorganism similar to bacteria but without a cell wall. It can be inoculated, grown and reproduced on inanimate artificial culture media. Drug sensitivity test refers to an in vitro test to determine the antibacterial or bactericidal ability of drugs. The sample of mycoplasma and other microorganisms, culture medium and corresponding staining liquid are mixed to obtain sample liquid, and then the sample liquid is distributed and injected or dripped into each culture well of the culture box, and paraffin oil is injected to complete the sample addition. Then the culture box is placed in an environment with a suitable temperature for cultivation. Finally, the drug sensitivity is judged by observing the color of the sample liquid (or mixture) in the culture box. At this stage, the mycoplasma analysis system needs to set up two sets of drive devices to assist in the injection of sample liquid and paraffin oil respectively, and the culture box needs to pass through each station in turn to complete the sample addition, which is inefficient. The structure volume and floor space of the sample addition device are large. Utility Model Content

[0003] The utility model aims to solve at least one of the technical problems existing in the prior art. To this end, the utility model provides a sample adding device for a mycoplasma analysis system, which has a compact structure and can improve the efficiency of sample adding.

[0004] According to an embodiment of the utility model, a sample loading device of a mycoplasma analysis system comprises a machine platform and a sample loading mechanism, wherein a culture box station for limiting a culture box is provided on the machine platform; the sample loading mechanism comprises a movable frame arranged on the machine platform, wherein the movable frame can move in the front-back and left-right directions, and a liquid suction component and an oil suction component which can be raised and lowered are provided on the movable frame, wherein the lower end of the liquid suction component is used for docking with a liquid suction head, wherein the liquid suction head is used for sucking a sample liquid and injecting the sample liquid into a culture hole of the culture box, and the lower end of the oil suction component is used for docking with an oil suction head, wherein the oil suction head is used for sucking paraffin oil and injecting the paraffin oil into the culture hole of the culture box.

[0005] The invention has at least the following beneficial effects: since the liquid suction component and the oil suction component are arranged on the same mobile frame, the mobile frame can simultaneously drive the liquid suction head and the oil suction head to move, initially the liquid suction head sucks a certain amount of sample liquid, the mobile frame moves to the top of the culture box station, the liquid suction head injects the sample liquid into the first empty culture well, then the mobile frame resets, the liquid suction head and the oil suction head suck a certain amount of sample liquid and paraffin oil respectively, the mobile frame moves to the top of the culture box station, the liquid suction head injects the sample liquid into the second empty culture well, the oil suction head injects the paraffin oil into the first culture well that has been injected with the sample liquid but not with the paraffin oil, and so on. In the continuous operation of the mobile frame, the mobile frame moves back and forth once to complete the injection of sample liquid and paraffin oil into a culture well until the sample addition work is completed, which can effectively improve the efficiency of sample addition.

[0006] According to some embodiments of the utility model, the utility model further comprises a limit plate, a culture box feeding mechanism, a cover opening mechanism and a bottle opening mechanism, all of which are provided on the machine platform, wherein the limit plate is provided with a paraffin oil bottle limit hole, a sample bottle clamp and a pipette tip carrier, the sample bottle clamp is used to clamp the sample bottle, the pipette tip carrier is used to set a plurality of liquid suction heads and a plurality of oil suction heads, and the paraffin oil bottle limit hole is used to set the paraffin oil bottle; the culture box feeding mechanism comprises a discharge track provided on the machine platform, and the front end of the discharge track is provided with the culture box station; the cover opening mechanism The structure is used to lift the lid of the culture box on the culture box station; the bottle opening mechanism is used to take away the bottle cap of the sample bottle on the sample bottle clamp; the lower end of the liquid suction component is used to connect with the liquid suction head on the tip carrier, and the liquid suction head is used to suck the sample liquid in the sample bottle and inject the sample liquid into the culture hole of the culture box; the lower end of the oil suction component is used to connect with the oil suction head on the tip carrier, and the oil suction head is used to suck the paraffin oil in the paraffin oil bottle and inject the paraffin oil into the culture hole of the culture box.

[0007] According to some embodiments of the utility model, a first supporting frame is provided on the machine platform, a first front-rear driving mechanism is provided on the first supporting frame, an output end of the first front-rear driving mechanism is connected to a first left-right driving mechanism, an output end of the first left-right driving mechanism is connected to the movable frame, a first lifting driving mechanism and a second lifting driving mechanism are provided on the movable frame, and the output ends of the first lifting driving mechanism and the second lifting driving mechanism are respectively connected to the liquid suction assembly and the oil suction assembly to respectively drive the liquid suction assembly and the oil suction assembly to lift and lower.

[0008] According to some embodiments of the utility model, the liquid pipetting assembly includes a first liquid pipetting syringe and a third lifting drive mechanism, the first liquid pipetting syringe and the third lifting drive mechanism are both connected to the output end of the first lifting drive mechanism through a first connecting plate, the lower end of the first liquid pipetting syringe faces downward and can be docked with the liquid pipetting head, and the output end of the third lifting drive mechanism is connected to the first piston rod of the first liquid pipetting syringe.

[0009] According to some embodiments of the utility model, the cover opening mechanism includes a first rotary drive mechanism arranged on the machine platform, a first swing arm arranged on the output end of the first rotary drive mechanism, and a suction nozzle arranged on the swing end of the first swing arm. The output end of the first rotary drive mechanism is horizontally arranged so that the first swing arm swings in a vertical plane, and the suction nozzle is used to adsorb the lid of the culture box on the culture box station.

[0010] According to some embodiments of the utility model, a second rotary drive mechanism is provided on the machine platform, a second swing arm is provided on the output end of the second rotary drive mechanism, a cover plate is provided on the swinging end of the second swing arm, the output end of the second rotary drive mechanism is vertically arranged so that the second swing arm swings in a horizontal plane, and the cover plate is used to cover the bottle mouth of the paraffin oil bottle on the limiting hole of the paraffin oil bottle.

[0011] According to some embodiments of the utility model, a semi-enclosure is provided at the lower end of the cover plate, and the semi-enclosure is used to surround the bottle mouth of the paraffin oil bottle.

[0012] According to some embodiments of the utility model, the culture box loading mechanism includes a feeding mechanism and a third front-rear driving mechanism, the number of the discharge tracks is two, the feeding mechanism is arranged at the rear ends of the two discharge tracks, the feeding mechanism is used to stack the culture boxes, the gap between the feeding mechanism and the discharge track is adapted to the height of the culture box, the third front-rear driving mechanism is arranged between the two discharge tracks, and a hook plate is connected to the output end of the third front-rear driving mechanism, and the hook plate is used to hook the bottom of the culture box to drive the culture box to move on the discharge track.

[0013] According to some embodiments of the utility model, the feeding mechanism includes a lower plate, an upper plate and a plurality of surrounding rods, the lower plate and the upper plate are connected together by the plurality of surrounding rods, the plurality of surrounding rods enclose a limiting space for limiting the culture box, the lower plate and the upper plate are both provided with a channel connected to the limiting space, and the rear ends of the lower plate and the upper plate are both provided with avoidance openings.

[0014] According to some embodiments of the utility model, the limiting plate is provided with a plurality of sample bottle positioning holes for positioning the sample bottle, the machine platform is provided with a second support frame, the second support frame is provided with a second front-and-rear driving mechanism, the output end of the second front-and-rear driving mechanism is connected to a second left-and-right driving mechanism, the output end of the second left-and-right driving mechanism is connected to a fifth lifting driving mechanism, the output end of the fifth lifting driving mechanism is connected to the bottle opening mechanism, the bottle opening mechanism is used to clamp the bottle cap of the sample bottle to transfer the sample bottle on the sample bottle positioning hole to the sample bottle clamp, and unscrew the bottle cap of the sample bottle on the sample bottle clamp.

[0015] According to some embodiments of the utility model, the bottle opening mechanism includes a mounting plate, a third rotation drive mechanism and a clamp, the mounting plate is connected to the output end of the fifth lifting drive mechanism, the third rotation drive mechanism is arranged on the mounting plate, and the output end of the third rotation drive mechanism is connected to the clamp.

[0016] Additional aspects and advantages of the present invention will be given in part in the following description, and in part will become apparent from the following description, or will be learned through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The present invention is further described below with reference to the accompanying drawings and embodiments, wherein:

[0018] Figure 1 This is a schematic diagram of the structure of a sample adding device of a mycoplasma analysis system according to an embodiment of the utility model;

[0019] Figure 2 This is a schematic diagram of the structure of a sample adding mechanism of a sample adding device of a mycoplasma analysis system according to an embodiment of the utility model;

[0020] Figure 3 This is a second structural schematic diagram of a sample adding mechanism of a sample adding device of a mycoplasma analysis system according to an embodiment of the utility model;

[0021] Figure 4 This is a schematic structural diagram of a limit plate, a cover opening mechanism and a discharge track of a mycoplasma analysis system according to an embodiment of the utility model;

[0022] Figure 5 This is a structural schematic diagram of a second rotary drive mechanism, a second swing arm and a cover plate of a mycoplasma analysis system according to an embodiment of the utility model;

[0023] Figure 6 This is a structural schematic diagram of a culture box loading mechanism of a mycoplasma analysis system according to an embodiment of the utility model;

[0024] Figure 7This is a schematic structural diagram of a second support frame, a second front-rear drive mechanism, a second left-right drive mechanism, a fifth lifting drive mechanism and a bottle opening mechanism of a sample adding device of a mycoplasma analysis system according to an embodiment of the utility model;

[0025] Figure Number:

[0026] Machine 100; limit plate 110; sample bottle clamp 111; pipette tip carrier 112; sample bottle positioning hole 113; first support frame 120; first front and rear drive mechanism 130; first left and right drive mechanism 140; second rotation drive mechanism 150; second swing arm 151; cover plate 152; semi-enclosure 153; second support frame 160; second front and rear drive mechanism 161; second left and right drive mechanism 162; fifth lifting drive mechanism 163;

[0027] Liquid suction head 200;

[0028] Oil suction head 300;

[0029] Cultivation box feeding mechanism 400; discharging track 410; feeding mechanism 420; lower plate 421; upper plate 422; surrounding rod 423; avoidance opening 424; third front and rear driving mechanism 430; hook plate 431;

[0030] Cover opening mechanism 500; first rotary drive mechanism 510; first swing arm 520; suction nozzle 530;

[0031] Bottle opening mechanism 600; mounting plate 610; third rotary drive mechanism 620; clamping claw 630;

[0032] Sample loading mechanism 700 ; moving frame 710 ; first lifting drive mechanism 711 ; second lifting drive mechanism 712 ; liquid suction assembly 720 ; first liquid suction syringe 721 ; third lifting drive mechanism 722 ; oil suction assembly 730 ; second liquid suction syringe 731 ; fourth lifting drive mechanism 732 . DETAILED DESCRIPTION

[0033] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0034] In the description of the present invention, it should be understood that descriptions involving orientation, such as up, down, front, back, left, right, etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0035] In the description of the present utility model, "a plurality" means more than two. If there is a description of "first" or "second", it is only for the purpose of distinguishing the technical features, and cannot be understood as indicating or implying the relative importance or implicitly indicating the number of the indicated technical features or implicitly indicating the order of the indicated technical features.

[0036] In the description of the present invention, unless otherwise clearly defined, terms such as setting, installing, connecting, etc. should be understood in a broad sense, and technicians in the relevant technical field can reasonably determine the specific meanings of the above terms in the present invention based on the specific content of the technical solution.

[0037] Reference Figure 1 and Figure 2 The utility model discloses a sample loading device for a mycoplasma analysis system, comprising a machine platform 100 and a sample loading mechanism 700. The machine platform 100 is provided with a culture box station for limiting a culture box; the sample loading mechanism 700 comprises a movable frame 710 arranged on the machine platform 100, the movable frame 710 can move in the front-back and left-right directions, and the movable frame 710 is provided with a liftable liquid suction component 720 and an oil suction component 730. The lower end of the liquid suction component 720 is used to dock with a liquid suction head 200, the liquid suction head 200 is used to suck sample liquid and inject the sample liquid into the culture hole of the culture box, and the lower end of the oil suction component 730 is used to dock with an oil suction head 300, the oil suction head 300 is used to suck paraffin oil and inject the paraffin oil into the culture hole of the culture box.

[0038] Since the liquid suction component 720 and the oil suction component 730 are arranged on the same mobile frame 710, the mobile frame 710 can simultaneously drive the liquid suction head 200 and the oil suction head 300 to move. Initially, the liquid suction head 200 absorbs a certain amount of sample liquid, and the mobile frame 710 moves to the top of the culture box station. The liquid suction head 200 injects the sample liquid into the first empty culture well. Then the mobile frame 710 is reset, and the liquid suction head 200 and the oil suction head 300 absorb a certain amount of sample liquid and paraffin oil respectively. The mobile frame 710 moves to the top of the culture box station, and the liquid suction head 200 injects the sample liquid into the second empty culture well, and the oil suction head 300 injects the paraffin oil into the first culture well that has been injected with the sample liquid but not with the paraffin oil, and so on. In the continuous operation of the mobile frame 710, the mobile frame 710 moves back and forth once to complete the injection of sample liquid and paraffin oil into a culture well until the sample addition work is completed, which can effectively improve the efficiency of sample addition. Furthermore, the liquid suction assembly 720, the oil suction assembly 730, the liquid suction head 200 and the oil suction head 300 are arranged on the same movable frame 710, so that the sample loading device can be more compact and occupy less space and area.

[0039] Reference Figures 2 to 4 In some embodiments, the loading device further comprises a machine platform 100 and a culture box loading mechanism 400, a cover opening mechanism 500, a bottle opening mechanism 600 and a loading mechanism 700, all of which are arranged on the machine platform 100. A limit plate 110 is provided on the machine platform 100, and a paraffin oil bottle limit hole, a sample bottle clamp 111 and a suction head carrier 112 are provided on the limit plate 110. The sample bottle clamp 111 is used to clamp the sample bottle, the suction head carrier 112 is used to set a plurality of liquid suction heads 200 and a plurality of oil suction heads 300, and the paraffin oil bottle limit hole is used to set the paraffin oil bottle; the culture box loading mechanism 400 comprises a discharge track 410 arranged on the machine platform 100, and a culture box station is provided at the front end of the discharge track 410; the cover opening mechanism 500 is used to lift the culture box The lid of the culture box on the culture box station; the bottle opening mechanism 600 is used to take away the bottle cap of the sample bottle on the sample bottle clamp 111; the sample adding mechanism 700 includes a movable frame 710 arranged on the machine table 100, and the movable frame 710 can move in the front and back and left and right directions. The movable frame 710 is provided with a liftable liquid suction component 720 and an oil suction component 730. The lower end of the liquid suction component 720 is used to dock with the liquid suction head 200 on the suction head carrier 112, and the liquid suction head 200 is used to suck the sample liquid in the sample bottle and inject the sample liquid into the culture hole of the culture box. The lower end of the oil suction component 730 is used to dock with the oil suction head 300 on the suction head carrier 112, and the oil suction head 300 is used to suck the paraffin oil in the paraffin oil bottle and inject the paraffin oil into the culture hole of the culture box.

[0040] When the mycoplasma analysis system is working, firstly, a paraffin oil bottle containing paraffin oil is placed in the paraffin oil bottle limiting hole, a plurality of liquid suction heads 200 and a plurality of oil suction heads 300 are placed on the suction head carrier 112, a sample bottle is placed on the sample bottle fixture 111, and a plurality of culture boxes are placed on the culture box loading mechanism 400. Of course, a liquid suction head 200 and an oil suction head 300 can be respectively connected to the liquid suction component 720 and the oil suction component 730 in advance.

[0041] The culture box loading mechanism 400 transports a single culture box to the culture box station at the front end of the discharge track 410, the bottle opening mechanism 600 can remove the bottle cap of the sample bottle on the sample bottle clamp 111, the liquid suction component 720 and the oil suction component 730 are respectively connected to a liquid suction head 200 and an oil suction head 300 (if a liquid suction head 200 and an oil suction head 300 are not pre-connected to the liquid suction component 720 and the oil suction component 730), the cover opening mechanism 500 lifts the cover of the culture box on the culture box station, the movable frame 710 carries the liquid suction component 720 and the liquid suction head 200 to the top of the limiting plate 110, the liquid suction head 200 extends into the sample bottle whose bottle cap has been removed and sucks a certain amount of sample liquid, the liquid suction head 200 withdraws from the sample bottle and moves to the top of the culture box whose cover has been lifted. The liquid suction component 720 drops or injects the sample liquid in the liquid suction head 200 into a culture well on the culture box. Similarly, the movable frame 710 drives the oil suction component 730 and the oil suction head 300 to move. The oil suction head 300 extends into the paraffin oil bottle and sucks a certain amount of paraffin oil. The oil suction head 300 withdraws from the paraffin oil bottle and moves to the top of the culture box whose lid has been lifted. The oil suction component 730 drops or injects the paraffin oil in the oil suction head 300 into the culture well that already has the sample liquid. Similarly, the movable frame 710 carries the liquid suction head 200 and the oil suction head 300 to move back and forth above the limiting plate 110 and above the culture box station, so as to inject the sample liquid and paraffin oil into different culture wells. When the culture box completes the injection of the sample liquid and paraffin oil, the culture box can be moved into the incubator for sample culture.

[0042] Since the liquid suction component 720 and the oil suction component 730 are arranged on the same mobile frame 710, when the mobile frame 710 is close to the paraffin oil bottle limiting hole on the limiting plate 110 and the sample bottle clamp 111, after the liquid suction head 200 and the oil suction head 300 respectively absorb a certain amount of sample liquid and paraffin oil, the mobile frame 710 moves to the top of the culture box station, and the liquid suction head 200 injects the sample liquid into the empty culture well, and the oil suction head 300 injects the paraffin oil into the culture well that has been injected with the sample liquid but not with the paraffin oil. It is equivalent to that the mobile frame 710 moves back and forth between the top of the limiting plate 110 and the top of the culture box station once, and the injection of sample liquid and paraffin oil into a culture well can be completed until the sample addition work is completed, which can effectively improve the efficiency of sample addition.

[0043] It can be understood that the spacing between the liquid absorption component 720 and the oil absorption component 730 is equal to the spacing between two adjacent culture wells on the same culture box. When the liquid absorption head 200 and the oil absorption head 300 are respectively connected to the liquid absorption component 720 and the oil absorption head 730, the spacing between the liquid absorption head 200 and the oil absorption head 300 is also equal to the spacing between two adjacent culture wells on the same culture box. At this time, the liquid absorption head 200 and the oil absorption head 300 can respectively inject sample liquid and paraffin oil into two adjacent culture wells, further improving the efficiency of sample addition.

[0044] It is understandable that the liquid suction head 200 and the oil suction head 300 can be the same component. The liquid suction head 200 is a pipe with a tapered lower end. Due to the difference in samples, to avoid contamination between samples, the liquid suction head 200 used for each sample or between each sample is different, that is, the liquid suction head 200 needs to be replaced frequently, while paraffin oil does not need to be replaced frequently. Setting an oil suction head 300 can also continuously perform the work of sucking paraffin oil from the paraffin oil bottle and injecting paraffin oil into the culture hole of the culture box.

[0045] Reference Figure 1 In some of the embodiments, a first support frame 120 is provided on the machine 100, and a first front-to-back driving mechanism 130 is provided on the first support frame 120. The output end of the first front-to-back driving mechanism 130 is connected to the first left-to-right driving mechanism 140, and the output end of the first left-to-right driving mechanism 140 is connected to the moving frame 710. The first support frame 120 supports the first front-to-back driving mechanism 130, the first left-to-right driving mechanism 140 and the moving frame 710. The first front-to-back driving mechanism 130 drives the first left-to-right driving mechanism 140 and the moving frame 710 to move in the front-to-back direction, and the first left-to-right driving mechanism 140 drives the moving frame 710 to move in the left-to-right direction, thereby realizing the front-to-back and left-to-right movement of the moving frame 710.

[0046] The movable frame 710 is provided with a first lifting drive mechanism 711 and a second lifting drive mechanism 712. The output ends of the first lifting drive mechanism 711 and the second lifting drive mechanism 712 are respectively connected to the liquid suction component 720 and the oil suction component 730. The first lifting drive mechanism 711 and the second lifting drive mechanism 712 respectively drive the liquid suction component 720 and the oil suction component 730 to rise and fall, thereby realizing the docking of the liquid suction component 720 with the liquid suction head 200 and driving the liquid suction head 200 to perform lifting and falling movements, thereby realizing the docking of the oil suction component 730 with the oil suction head 300 and driving the oil suction head 300 to perform lifting and falling movements.

[0047] Reference Figure 2 and Figure 3In some embodiments, the liquid suction component 720 includes a first liquid suction syringe 721 and a third lifting drive mechanism 722. The first liquid suction syringe 721 and the third lifting drive mechanism 722 are both connected to the output end of the first lifting drive mechanism 711 through a first connecting plate. The first lifting drive mechanism 711 drives the first liquid suction syringe 721 and the third lifting drive mechanism 722 to rise and fall synchronously.

[0048] The lower end of the first pipette syringe 721 faces downward and can be connected to the pipette head 200. The output end of the third lifting drive mechanism 722 is connected to the first piston rod of the first pipette syringe 721. When the first lifting drive mechanism 711 drives the first pipette syringe 721 and the third lifting drive mechanism 722 to descend, the pipette head 200 on the lower end of the first pipette syringe 721 can be extended into the sample bottle. The third lifting drive mechanism 722 drives the first piston rod to rise, and the first pipette syringe 721 can complete the suction of the sample liquid. When the third lifting drive mechanism 722 drives the first piston rod to descend, the sample liquid in the first pipette syringe 721 will be discharged through the pipette head 200 or injected into the culture hole.

[0049] Similarly, the oil suction assembly 730 includes a second suction syringe 731 and a fourth lifting drive mechanism 732. The second suction syringe 731 and the fourth lifting drive mechanism 732 are both connected to the output end of the second lifting drive mechanism 712 through a second connecting plate. The lower end of the second suction syringe 731 faces downward and can be connected to the oil suction head 300. The output end of the fourth lifting drive mechanism 732 is connected to the second piston rod of the second suction syringe 731.

[0050] It can be understood that the first front-rear driving mechanism 130 , the first left-right driving mechanism 140 , the first lifting driving mechanism 711 , the second lifting driving mechanism 712 , the third lifting driving mechanism 722 and the fourth lifting driving mechanism 732 can all be cylinders or screw pairs.

[0051] Reference Figure 1In this embodiment, the first front-to-back driving mechanism 130 is a belt driving mechanism, which includes a first belt, a second belt, a third belt and a fourth belt, and a first motor, a first pulley, a second pulley, a third pulley and a fourth pulley, all of which are arranged on the first support frame 120. The first pulley, the second pulley and the third pulley each have two pulley surfaces, and the central axes of the first pulley, the second pulley, the third pulley and the fourth pulley are all vertically arranged. The first pulley, the second pulley, the third pulley and the fourth pulley are distributed in four corners, and the first pulley, the second pulley, The third pulley and the fourth pulley are connected in sequence to form a rectangle, the line connecting the first pulley and the fourth pulley is in the left and right direction, the first pulley is directly in front of the second pulley, the fourth pulley is directly in front of the third pulley, the first belt is wound around the output end of the first belt and the first pulley, the second belt is wound around the first pulley and the second pulley, the third belt is wound around the second pulley and the third pulley, the fourth belt is wound around the third pulley and the fourth pulley, the first motor can drive the first belt, the second belt, the third belt and the fourth belt to rotate at the same time, and the two ends of the cross plate are respectively connected to the second belt and the fourth belt.

[0052] The first support frame 120 is provided with a first sliding mechanism and a second sliding mechanism, which are distributed left and right and both run forward and backward, and the first sliding mechanism and the second sliding mechanism are straddled with a cross plate, the first left and right driving mechanism 140 is provided on the cross plate, and the third sliding mechanism is provided on the cross plate, the movable frame 710 is connected to the cross plate through the third sliding mechanism, and the output end of the first left and right driving mechanism 140 is connected to the movable frame 710.

[0053] Reference Figure 4 In some embodiments, the cover opening mechanism 500 includes a first rotary drive mechanism 510 disposed on the machine 100, a first swing arm 520 disposed on the output end of the first rotary drive mechanism 510, and a suction nozzle 530 disposed on the swing end of the first swing arm 520. The output end of the first rotary drive mechanism 510 is horizontally arranged, and the suction nozzle 530 is used to absorb the lid of the culture box on the culture box station. The first rotary drive mechanism 510 drives the first swing arm 520 to swing in a vertical plane, so that the suction nozzle 530 can move along an arc track on the vertical plane. When the suction nozzle 530 is in a low position, the suction nozzle 530 is against the lid of the culture box on the culture box station and can absorb the lid. Then, when the first swing arm 520 swings upward, the suction nozzle 530 carries the lid and moves to the upper side of the box body of the culture box, so as to avoid the first swing arm 520 and the suction nozzle 530 from interfering with the liquid suction head 200 and the oil suction head 300.

[0054] It is conceivable that the first rotation driving mechanism 510 is a second motor, and the suction nozzle 530 is connected to a negative pressure device.

[0055] Reference Figure 4 and Figure 5 In some embodiments, a second rotary drive mechanism 150 is provided on the machine 100, a second swing arm 151 is provided on the output end of the second rotary drive mechanism 150, a cover plate 152 is provided on the swing end of the second swing arm 151, the output end of the second rotary drive mechanism 150 is vertically arranged, the second rotary drive mechanism 150 drives the second swing arm 151 to swing in a horizontal plane, and the cover plate 152 moves with the second swing arm 151, so that the cover plate 152 blocks the bottle mouth of the paraffin oil bottle on the limiting hole of the paraffin oil bottle or avoids the bottle mouth of the paraffin oil bottle. When the cover plate 152 blocks the bottle mouth of the paraffin oil bottle, foreign matter can be prevented from entering the paraffin oil bottle to contaminate the paraffin oil. When the cover plate 152 avoids the bottle mouth of the paraffin oil bottle, the oil suction head 300 can extend into the paraffin oil bottle through the bottle mouth of the paraffin oil bottle.

[0056] In some embodiments, a semi-enclosure 153 is provided at the lower end of the cover plate 152, and the semi-enclosure 153 forms a gap. When the cover plate 152 swings with the semi-enclosure 153, the bottle mouth of the paraffin oil bottle can pass through the gap, so that the semi-enclosure 153 can be against the bottle mouth of the paraffin oil bottle, avoiding that the cover plate 152 cannot completely cover the bottle mouth of the paraffin oil bottle due to excessive swinging. It is conceivable that the second rotation drive mechanism 150 is a third motor.

[0057] See also Figure 6 In some embodiments, the culture box loading mechanism 400 includes a feeding mechanism 420 and a third front-rear driving mechanism 430. There are two discharge tracks 410. The feeding mechanism 420 is arranged at the rear ends of the two discharge tracks 410. The feeding mechanism 420 is used to stack the culture boxes. The gap between the feeding mechanism 420 and the discharge track 410 is adapted to the height of the culture boxes. The feeding mechanism 420 serves to temporarily store multiple culture boxes. The lowest culture box on the feeding mechanism 420 falls on the two discharge tracks 410 and can slide on the two discharge tracks 410.

[0058] The third front-to-back driving mechanism 430 is arranged between the two discharge tracks 410. A hook plate 431 is connected to the output end of the third front-to-back driving mechanism 430. The hook plate 431 is used to hook the bottom of the culture box. When the third front-to-back driving mechanism 430 drives the hook plate 431 to move from back to front, the rear end of the culture box on the discharge track 410 can be driven to move to the front end on the discharge track 410, that is, the culture box is transported to the culture box station.

[0059] It is conceivable that the third front-to-back driving mechanism 430 is a belt driving mechanism. The output end of the third front-to-back driving mechanism 430 is connected to a support plate, a storage slot is provided on the support plate, an elastic member is provided in the storage slot, the lower end of the hook plate 431 extends into the storage slot and abuts against the elastic member, the upper end of the hook plate 431 is wedge-shaped, the inclined surface of the hook plate 431 faces backward and upward, the hook plate 431 moves from front to back, and when the inclined surface of the hook plate 431 hits the front edge of the culture box, the culture box can drive the hook plate 431 to move downward and compress the elastic member, so that the hook plate 431 passes over the front edge of the culture box and extends into the slot at the bottom of the culture box.

[0060] In another embodiment, the output end of the third front-rear driving mechanism 430 is connected to a support plate, and a hook plate 431 is disposed on the support plate. The upper end of the hook plate 431 is wedge-shaped, and the inclined surface of the hook plate 431 faces upward and backward. The hook plate 431 moves from front to back. When the inclined surface of the hook plate 431 hits the front edge of the culture box, the hook plate 431 can drive the culture box to rise, so that the hook plate 431 passes over the front edge of the culture box and extends into the groove at the bottom of the culture box.

[0061] Reference Figure 6 In some embodiments, the feeding mechanism 420 includes a lower plate 421, an upper plate 422 and a plurality of surrounding rods 423. The lower plate 421 and the upper plate 422 are connected together by the plurality of surrounding rods 423. The plurality of surrounding rods 423 enclose a limiting space for limiting the position of the culture box. The lower plate 421 and the upper plate 422 are both provided with a channel connected to the limiting space, and a plurality of culture boxes can be placed in the limiting space from top to bottom. The rear ends of the lower plate 421 and the upper plate 422 are both provided with an avoidance opening 424, and the avoidance opening 424 can be used for parts such as hands and clamps to pass through, so as to facilitate the placement of the culture box in the limiting space.

[0062] See also Figure 2 and Figure 4 In some embodiments, the limiting plate 110 is provided with a plurality of sample bottle positioning holes 113 for positioning the sample bottles. The plurality of sample bottles can be placed in the sample bottle positioning holes 113 respectively, and the sample liquids in each sample bottle can be different.

[0063] Reference Figure 1 and Figure 7A second support frame 160 is provided on the machine 100, and a second front-to-back driving mechanism 161 is provided on the second support frame 160. The output end of the second front-to-back driving mechanism 161 is connected to a second left-to-right driving mechanism 162, and the output end of the second left-to-right driving mechanism 162 is connected to a fifth lifting driving mechanism 163. The output end of the fifth lifting driving mechanism 163 is connected to a bottle opening mechanism 600. The bottle opening mechanism 600 is used to clamp the sample bottle. The second front-to-back driving mechanism 161, the second left-to-right driving mechanism 162 and the fifth lifting driving mechanism 163 respectively drive the bottle opening mechanism 600 to move in the front-to-back, left-to-right and up-to-down directions. The bottle opening mechanism 600 can transfer the sample bottle on the sample bottle positioning hole 113 to the sample bottle clamp 111. The sample bottle clamp 111 clamps the bottle body of the sample bottle, and the bottle opening mechanism 600 can rotate and unscrew the bottle cap of the sample bottle on the sample bottle clamp 111.

[0064] In some embodiments, the bottle opening mechanism 600 includes a mounting plate 610, a third rotating drive mechanism 620, and a clamping claw 630. The mounting plate 610 is connected to the output end of the fifth lifting drive mechanism 163. The third rotating drive mechanism 620 is arranged on the mounting plate 610. The output end of the third rotating drive mechanism 620 is connected to the clamping claw 630. The fifth lifting drive mechanism 163 can drive the mounting plate 610 and the third rotating drive mechanism 620 to rise and fall, thereby driving the clamping claw 630 to rise and fall. The third rotating drive mechanism 620 drives the clamping claw 630 to rotate, thereby realizing that the clamping claw 630 twists the bottle cap of the sample bottle. The clamping claw 630 is a common opening and closing clamping mechanism.

[0065] The second front-rear driving mechanism 161, the second left-right driving mechanism 162 and the fifth lifting driving mechanism 163 can all be cylinders, lead screws or belt driving mechanisms. The third rotation driving mechanism 620 can be a fourth motor.

[0066] The technical features of the above embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0067] Of course, the present invention is not limited to the above-mentioned embodiments, and technicians familiar with the field may make equivalent modifications or substitutions without violating the spirit of the present invention. These equivalent modifications or substitutions are all included in the scope defined by the claims of this application.

Claims

1. A sample adding device for a mycoplasma analysis system, characterized in that: include: The machine is provided with a culture box station for limiting the culture box; The sample loading mechanism comprises a movable frame arranged on the machine platform, the movable frame can move in the front-back and left-right directions, and a liquid suction component and an oil suction component that can be raised and lowered are arranged on the movable frame, the lower end of the liquid suction component is used to dock with a liquid suction head, the liquid suction head is used to suck the sample liquid and inject the sample liquid into the culture hole of the culture box, and the lower end of the oil suction component is used to dock with an oil suction head, the oil suction head is used to suck the paraffin oil and inject the paraffin oil into the culture hole of the culture box.

2. The sample adding device of the mycoplasma analysis system according to claim 1, characterized in that: Also includes: A limit plate is arranged on the machine platform, and a paraffin oil bottle limit hole, a sample bottle clamp and a suction head carrier are arranged on the limit plate. The sample bottle clamp is used to clamp the sample bottle, the suction head carrier is used to set a plurality of liquid suction heads and a plurality of oil suction heads, and the paraffin oil bottle limit hole is used to set the paraffin oil bottle; A culture box loading mechanism, comprising a discharge track arranged on the machine platform, wherein the front end of the discharge track is provided with the culture box station; A cover opening mechanism, provided on the machine platform, for lifting the cover of the culture box on the culture box station; A bottle opening mechanism, disposed on the machine platform, for removing the bottle cap of the sample bottle on the sample bottle fixture; The lower end of the liquid suction component is used to dock with the liquid suction head on the tip carrier, and the liquid suction head is used to aspirate the sample liquid in the sample bottle and inject the sample liquid into the culture well of the culture box. The lower end of the oil suction component is used to dock with the oil suction head on the tip carrier, and the oil suction head is used to aspirate the paraffin oil in the paraffin oil bottle and inject the paraffin oil into the culture well of the culture box.

3. The sample adding device of the mycoplasma analysis system according to claim 2, characterized in that: A first supporting frame is provided on the machine platform, a first front-to-back driving mechanism is provided on the first supporting frame, an output end of the first front-to-back driving mechanism is connected to a first left-to-right driving mechanism, an output end of the first left-to-right driving mechanism is connected to the moving frame, a first lifting driving mechanism and a second lifting driving mechanism are provided on the moving frame, and output ends of the first lifting driving mechanism and the second lifting driving mechanism are respectively connected to the liquid suction assembly and the oil suction assembly to respectively drive the liquid suction assembly and the oil suction assembly to lift and lower.

4. The sample adding device of the mycoplasma analysis system according to claim 3, characterized in that: The liquid pipetting assembly includes a first liquid pipetting syringe and a third lifting drive mechanism. The first liquid pipetting syringe and the third lifting drive mechanism are both connected to the output end of the first lifting drive mechanism through a first connecting plate. The lower end of the first liquid pipetting syringe faces downward and can be connected to the liquid pipetting head. The output end of the third lifting drive mechanism is connected to the first piston rod of the first liquid pipetting syringe.

5. The sample adding device of the mycoplasma analysis system according to claim 2, characterized in that: The lid opening mechanism includes a first rotary drive mechanism arranged on the machine platform, a first swing arm arranged on the output end of the first rotary drive mechanism, and a suction nozzle arranged on the swing end of the first swing arm. The output end of the first rotary drive mechanism is horizontally arranged so that the first swing arm swings in a vertical plane. The suction nozzle is used to adsorb the lid of the culture box on the culture box station.

6. The sample adding device of the mycoplasma analysis system according to claim 2, characterized in that: A second rotary drive mechanism is provided on the machine platform, a second swing arm is provided on the output end of the second rotary drive mechanism, a cover plate is provided on the swing end of the second swing arm, the output end of the second rotary drive mechanism is vertically arranged so that the second swing arm swings in a horizontal plane, and the cover plate is used to cover the bottle mouth of the paraffin oil bottle on the limiting hole of the paraffin oil bottle.

7. The sample adding device of the mycoplasma analysis system according to claim 6, characterized in that: A semi-enclosure is provided at the lower end of the cover plate, and the semi-enclosure is used to surround the bottle mouth of the paraffin oil bottle.

8. The sample adding device of the mycoplasma analysis system according to claim 2, characterized in that: The culture box loading mechanism includes a feeding mechanism and a third front-to-back driving mechanism. There are two discharge tracks. The feeding mechanism is arranged at the rear ends of the two discharge tracks. The feeding mechanism is used to stack the culture boxes. The gap between the feeding mechanism and the discharge track is adapted to the height of the culture box. The third front-to-back driving mechanism is arranged between the two discharge tracks. A hook plate is connected to the output end of the third front-to-back driving mechanism. The hook plate is used to hook the bottom of the culture box to drive the culture box to move on the discharge track.

9. The sample adding device of the mycoplasma analysis system according to claim 8, characterized in that: The feeding mechanism includes a lower plate, an upper plate and a plurality of surrounding rods, the lower plate and the upper plate are connected together by the plurality of surrounding rods, the plurality of surrounding rods enclose a limiting space for limiting the culture box, the lower plate and the upper plate are both provided with a channel connected to the limiting space, and the rear ends of the lower plate and the upper plate are both provided with avoidance openings.

10. The sample adding device of the mycoplasma analysis system according to claim 2, characterized in that: The limiting plate is provided with a plurality of sample bottle positioning holes for positioning the sample bottle, the machine platform is provided with a second support frame, the second support frame is provided with a second front-and-rear driving mechanism, the output end of the second front-and-rear driving mechanism is connected to a second left-and-right driving mechanism, the output end of the second left-and-right driving mechanism is connected to a fifth lifting driving mechanism, the output end of the fifth lifting driving mechanism is connected to the bottle opening mechanism, the bottle opening mechanism is used to clamp the bottle cap of the sample bottle to transfer the sample bottle on the sample bottle positioning hole to the sample bottle clamp, and unscrew the bottle cap of the sample bottle on the sample bottle clamp.

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