Tissue treatment device

Abstract

The utility model discloses a tissue treatment device which comprises a treatment pipe and a rotary cutting and grinding assembly, and a stator grinding wall is arranged at the lower end of the treatment pipe. The rotary cutting and grinding assembly comprises a rotor grinding wall; at least one and at least one layer of first cutting and grinding blocks are arranged on the outer surface of the rotor grinding wall, at least one and at least one layer of second cutting and grinding blocks are arranged on the inner surface of the stator grinding wall, and the first cutting and grinding blocks and the second cutting and grinding blocks are arranged in a staggered manner. The tissue treatment device is innovatively designed, through the first cutting and grinding block and the second cutting and grinding block, tissue is cut and ground at the same time in one working procedure during tissue treatment, and the treatment process is greatly simplified.

Description

Technical Field

[0001] The utility model relates to the technical field of biological tissue grinding, in particular to a tissue processing device. Background Art

[0002] The main methods of culturing cells in vitro are adherent culture and suspension culture. In recent years, adherent cells (such as mesenchymal stem cells) have shown considerable research value and application prospects in many fields. However, most adherent cells come from solid tissues, and the tissues often need to be processed during the initial separation. There are two methods for separating adherent cells: adherent culture and digestion. The adherent culture method requires cutting the tissue into small pieces, while the digestion method also requires pre-cutting and grinding the tissue in order to increase the contact area between the tissue and the digestive enzyme. The existing tissue processing methods mainly involve cutting with scissors or grinding with a mortar, which is cumbersome to operate and not conducive to the collection of processed tissues.

[0003] Therefore, in response to the needs of tissue processing, the utility model has made innovations in the tissue processing method, using a set of devices to simultaneously cut and grind the tissue and conveniently collect the processed tissue, thus solving the problems of troublesome tissue processing and difficult collection. Utility Model Content

[0004] In view of the above-mentioned defects in the prior art, the purpose of the present invention is to provide a tissue processing device to solve the problem of cumbersome tissue processing and difficult collection when separating adherent cells.

[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0006] A tissue processing device comprises a processing tube, a processing tube cover is arranged at the upper end of the processing tube, a stator grinding wall is arranged at the lower end of the processing tube, an outflow outlet is arranged at the lower end of the stator grinding wall, and the outflow outlet is provided with an outlet cover, and also comprises a rotating cutting and grinding assembly; a socket is arranged at the upper end of the outlet cover; the rotating cutting and grinding assembly comprises a hand crank, a long rod, and a rotor grinding wall; the upper end of the long rod is connected to the hand crank, the long rod passes through the processing tube cover and is inserted into the socket of the outlet cover, and the rotor grinding wall is fixedly connected to the long rod; at least one and at least one layer of first cutting and grinding blocks are arranged on the outer surface of the rotor grinding wall, and at least one and at least one layer of second cutting and grinding blocks are arranged on the inner surface of the stator grinding wall, and the first cutting and grinding blocks and the second cutting and grinding blocks are arranged alternately.

[0007] Furthermore, the first cutting and grinding block and the second cutting and grinding block both include a bullet-shaped pointed head and a round blunt head, the pointed head is provided with a cutting knife, the blunt head is provided with a grinding head, and the bullet-shaped pointed head and the round blunt head have a smooth transition.

[0008] Furthermore, the distance between the outer surface of the rotor grinding wall and the inner surface of the stator grinding wall is less than the sum of the heights of the first cutting grinding block and the second cutting grinding block, and greater than the height of the first cutting grinding block or the second cutting grinding block itself.

[0009] Furthermore, the rotor grinding wall and the stator grinding wall are conical walls with the same taper.

[0010] Furthermore, the processing tube cover and the processing tube, and the outflow port and the outlet cover are all connected by threads.

[0011] Furthermore, the processing tube cover is an airtight bottle cap.

[0012] Furthermore, the outlet cover is an airtight cover.

[0013] Furthermore, taking the cutting directions of the first cutting and grinding block and the second cutting and grinding block as the rotation direction, the rotation directions of the first cutting and grinding block and the second cutting and grinding block are opposite.

[0014] Furthermore, the first cutting and grinding block has a clockwise rotation direction, and the second cutting and grinding block has a counterclockwise rotation direction.

[0015] Furthermore, the hand crank, processing tube cover, processing tube, long rod, rotor grinding wall, stator grinding wall, outlet cover body, second cutting grinding block, and first cutting grinding block are all made of PP, i.e., polypropylene; the rotor grinding wall and the first cutting grinding block are integrated; the stator grinding wall and the second cutting grinding block are integrated.

[0016] Compared with the prior art, the utility model has the following beneficial effects:

[0017] (1) The utility model innovatively designs a tissue processing device, which realizes the simultaneous cutting and grinding of tissue in one process during tissue processing through a first cutting and grinding block and a second cutting and grinding block, thereby greatly simplifying the processing flow.

[0018] (2) The utility model collects the processed tissue through the outflow port, which is convenient and easy to operate. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 The utility model is a structural schematic diagram of a tissue processing device.

[0020] In the figure: 1. hand crank; 2. processing tube cover; 3. processing tube; 4. long rod; 5. rotor grinding wall; 6. stator grinding wall; 7. outlet cover; 8. second cutting grinding block; 9. first cutting grinding block. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model. Example

[0022] See also Figure 1 , the utility model provides a tissue processing device, comprising a processing tube 3, a rotating cutting and grinding assembly;

[0023] A processing tube cover 2 is disposed at the upper end of the processing tube 3, a stator grinding wall 6 is disposed at the lower end of the processing tube 3, a flow outlet is disposed at the lower end of the stator grinding wall 6, an outlet is disposed at the flow outlet, an outlet cover 7 is disposed at the upper end of the outlet cover 7, and a plug hole is disposed at the upper end;

[0024] The rotary cutting and grinding assembly comprises a hand crank 1, a long rod 4, and a rotor grinding wall 5. The upper end of the long rod 4 is connected to the hand crank 1. The long rod 4 passes through the processing tube cover 2 and is inserted into the jack of the outlet cover 7. The rotor grinding wall 5 is fixedly connected to the long rod 4.

[0025] The outer surface of the rotor grinding wall 5 is provided with at least one and at least one layer of first cutting and grinding blocks 9, and the inner surface of the stator grinding wall 6 is provided with at least one and at least one layer of second cutting and grinding blocks 8, and the first cutting and grinding blocks 9 and the second cutting and grinding blocks 8 are arranged alternately.

[0026] Specifically, the first cutting and grinding block 9 and the second cutting and grinding block 8 both include a bullet-shaped pointed head and a round blunt head, the pointed head is provided with a cutting knife, the blunt head is provided with a grinding head, and the bullet-shaped pointed head and the round blunt head have a smooth transition.

[0027] Specifically, the distance between the outer surface of the rotor grinding wall 5 and the inner surface of the stator grinding wall 6 is less than the sum of the heights of the first cutting and grinding block 9 and the second cutting and grinding block 8, and greater than the height of the first cutting and grinding block 9 or the second cutting and grinding block 8 itself.

[0028] Specifically, the rotor grinding wall 5 and the stator grinding wall 6 are conical walls with the same taper.

[0029] Specifically, the processing tube cover 2 and the processing tube 3, and the outflow port and the outlet cover 7 are connected by threads.

[0030] Specifically, the processing tube cover 2 is an airtight bottle cover, which is screwed to the processing tube via threads.

[0031] Specifically, the outlet cover 7 is an airtight cover.

[0032] Specifically, the cutting directions of the first cutting and grinding block 9 and the second cutting and grinding block 8 are taken as the rotation direction, and the rotation directions of the first cutting and grinding block 9 and the second cutting and grinding block 8 are opposite.

[0033] Specifically, the hand crank 1, the processing tube cover 2, the processing tube 3, the long rod 4, the rotor grinding wall 5, the stator grinding wall 6, the cover body of the outlet cover 7, the second cutting and grinding block 8, and the first cutting and grinding block 9 are all made of PP, that is, polypropylene. The rotor grinding wall 5 and the first cutting and grinding block 9 are integrated and manufactured by a mold, and the stator grinding wall 6 and the second cutting and grinding block 8 are integrated and manufactured by a mold.

[0034] The long rod 4 drives the rotor grinding wall 5 to rotate by rotating the hand crank 1.

[0035] Among them, the first cutting and grinding block 9 and the second cutting and grinding block 8 with opposite rotation directions, when the rotor grinding wall 5 rotates toward the rotation direction of the first cutting and grinding block 9, the bullet-shaped pointed heads interact with each other to cut the tissue; when the rotor grinding wall 5 rotates toward the rotation direction of the second cutting and grinding block 8, the round blunt heads interact with each other to grind the tissue.

[0036] The insertion hole at the upper end of the outlet cover 7 realizes the axial positioning of the long rod 4, and the long rod 4 can rotate in the insertion hole, and the processed tissue can be collected by unscrewing the outlet cover 7. Example

[0037] Based on Example 1, specifically, the first cutting and grinding block 9 rotates clockwise, and the second cutting and grinding block 8 rotates counterclockwise.

[0038] When using, follow the steps below:

[0039] When in use, the tissue processing device is placed on a centrifuge tube rack in a biosafety cabinet, the processing tube cover 2 is opened, the tissue to be processed is added into the device, and then the processing tube cover 2 is closed.

[0040] If the tissue is to be cut or shredded, the hand crank 1 is rotated clockwise; if the tissue is to be ground, the hand crank 1 is rotated counterclockwise. Alternating clockwise and counterclockwise rotation of the hand crank 1 can simultaneously complete the tissue cutting, shredding and grinding operations.

[0041] After the operation is finished, the outlet cover 7 is opened to collect the processed tissue.

[0042] All components and connection methods of components not discussed in this application belong to the known technologies in this technical field and can be directly applied without further explanation.

[0043] In the present invention, the term "plurality" means two or more than two, unless otherwise clearly defined. The terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense. For example, "connect" can be a fixed connection, a detachable connection, or an integral connection; "connected" can be a direct connection or an indirect connection through an intermediate medium. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to the specific circumstances.

[0044] In the description of the present invention, it is necessary to understand that the directions or positional relationships indicated by terms such as "up", "down", "left", "right", "front" and "back" are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or unit referred to must have a specific direction, be constructed and operated in a specific orientation, and therefore, cannot be understood as a limitation on the present invention.

[0045] In the description of this specification, the description of the terms "one embodiment", "some embodiments", "specific embodiments", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0046] The above description is only the preferred embodiment of the utility model, and is not intended to limit the utility model. For those skilled in the art, the utility model can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A tissue processing device, comprising a processing tube, a processing tube cover is arranged at the upper end of the processing tube, a stator grinding wall is arranged at the lower end of the processing tube, an outflow port is arranged at the lower end of the stator grinding wall, and an outlet cap is arranged at the outflow port, characterized in that: Also included is a rotary cutting and grinding assembly; The upper end of the outlet cover is provided with a plug hole; The rotary cutting and grinding assembly comprises a hand crank, a long rod, and a rotor grinding wall; the upper end of the long rod is connected to the hand crank, the long rod passes through the processing tube cover and is inserted into the jack of the outlet cover, and the rotor grinding wall is fixedly connected to the long rod; The outer surface of the rotor grinding wall is provided with at least one and at least one layer of first cutting and grinding blocks, and the inner surface of the stator grinding wall is provided with at least one and at least one layer of second cutting and grinding blocks, and the first cutting and grinding blocks and the second cutting and grinding blocks are arranged alternately.

2. A tissue processing device according to claim 1, characterized in that: The first cutting and grinding block and the second cutting and grinding block both include a bullet-shaped pointed head and a round blunt head. The pointed head is provided with a cutting knife, and the blunt head is provided with a grinding head. The bullet-shaped pointed head and the round blunt head have a smooth transition.

3. A tissue processing device according to claim 1, characterized in that: The distance between the outer surface of the rotor grinding wall and the inner surface of the stator grinding wall is less than the sum of the heights of the first cutting grinding block and the second cutting grinding block, and greater than the height of the first cutting grinding block or the second cutting grinding block itself.

4. A tissue processing device according to claim 1, characterized in that: The rotor grinding wall and the stator grinding wall are conical walls with the same taper.

5. The tissue processing device according to claim 1, characterized in that: The processing tube cover and the processing tube, and the outflow port and the outlet cover are all connected by threads.

6. A tissue processing device according to claim 1, characterized in that: The processing tube cap is an airtight bottle cap.

7. The tissue processing device according to claim 1, characterized in that: The outlet cover is an airtight cover.

8. The tissue processing device according to claim 1, characterized in that: The cutting directions of the first cutting and grinding block and the second cutting and grinding block are taken as the rotation direction, and the rotation directions of the first cutting and grinding block and the second cutting and grinding block are opposite.

9. A tissue processing device according to claim 8, characterized in that: The first cutting and grinding block has a clockwise rotation direction, and the second cutting and grinding block has a counterclockwise rotation direction.

10. A tissue processing device according to any one of claims 1 to 9, characterized in that: The hand crank, the processing tube cover, the processing tube, the long rod, the rotor grinding wall, the stator grinding wall, the cover of the outlet cover, the second cutting and grinding block, and the first cutting and grinding block are all made of PP, that is, polypropylene; The rotor grinding wall and the first cutting and grinding block are integrated; The stator grinding wall and the second cutting and grinding block are integrated.

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