Sterilizing filter for raw material medicine production

Abstract

The utility model discloses a degerming filter for raw material medicine production, which comprises a degerming filter box body and a steam furnace, a moving plate is arranged on the outer side of the bottom of the degerming filter box body, the steam furnace is arranged at the upper end of the moving plate, a steam cavity is arranged at the upper end of the steam furnace, and a heat preservation conveying pipe is arranged at the upper end of the steam cavity. And a pipeline connector is arranged on the outer wall of the sterilizing and filtering box body, a sealing cover is installed at the top end of the sterilizing and filtering box body, and a feeding opening is formed in the upper end of the sealing cover. According to the degerming filter for raw material medicine production, steam is conveyed into the degerming filter box through the heat preservation conveying pipe, due to the fact that pure steam is high in penetrability, protein and protoplast colloid are used for denaturation and solidification under the humid and hot conditions, an enzyme system is prone to being damaged, the steam enters cells to be condensed into water, potential heat can be released, and the temperature can be increased; and the sterilizing power is enhanced, so that the sterilizing and filtering box body is disinfected and sterilized.

Description

Technical Field

[0001] The utility model relates to the technical field of raw material medicines, in particular to a sterilization filter for the production of raw material medicines. Background Art

[0002] APIs refer to the APIs used to produce various preparations. They are the active ingredients in the preparations. They are various powders, crystals, extracts, etc. prepared by chemical synthesis, plant extraction or biotechnology for medicinal purposes, but are substances that patients cannot take directly. When handling APIs, it is necessary to ensure the cleanliness of the environment. In this case, the APIs can be sterilized and filtered through a sterilizing filter. Sterilization is a functional definition. Sterilization filtration is a process that uses physical interception methods to remove microorganisms from liquids, powders or gases to meet the requirements of sterile drugs. In the pharmaceutical industry, since drugs will eventually enter the human body, aseptic production processes are crucial.

[0003] As shown in application number CN201920483409.1, the utility model discloses a sterilizing filter, which relates to the technical field of filters, including a kettle body, a shell body installed on the top wall of the kettle body, and the shell body including a first shell, one side of the first shell is connected to an air inlet pipe, and the other side of the first shell is connected to an air outlet pipe, the air inlet pipe and the air outlet pipe are connected to the inner cavity of the first shell, and the air outlet pipe is connected to the kettle body away from the end connected to the first shell; the first shell is connected to a second shell on one side, and the second shell is connected to a drive assembly away from the end connected to the first shell; a connecting pipe is installed in the first shell, and a filter element is installed in the second shell, one end of the connecting pipe is connected to the air outlet pipe, and the other end of the connecting pipe is connected to the air outlet end of the filter element. The utility model has the effect of preventing the accumulated microorganisms and impurities from squeezing the filter pores of the filter element to enlarge the pore size.

[0004] Similar to the above application, there are still the following deficiencies:

[0005] There will be residual bacteria that have not been eliminated inside the existing device, and subsequent work will cause contamination to the drugs, affecting the production of the drugs.

[0006] Therefore, in view of this, the existing structure and deficiencies are studied and improved, and a sterilizing filter for raw material drug production is proposed, in order to achieve a more practical purpose. Utility Model Content

[0007] The purpose of the utility model is to provide a sterilizing filter for the production of bulk drugs to solve the problems raised in the above-mentioned background technology.

[0008] To achieve the above object, the present utility model provides the following technical solutions: A sterilizing filter for raw material drug production, comprising a sterilizing filter box body and a steam furnace. A moving plate is arranged on the outer side of the bottom of the sterilizing filter box body, and the steam furnace is installed at the upper end of the moving plate. A steam chamber is arranged at the upper end of the steam furnace, and a heat preservation conveying pipe is arranged at the upper end of the steam chamber. A pipeline interface is arranged on the outer wall of the sterilizing filter box body, and a sealing cover is installed at the top of the sterilizing filter box body. A feed inlet is opened at the upper end of the sealing cover.

[0009] Further, a receiving drawer is installed inside the bottom end of the sterilizing filter box body, and a connecting groove is arranged on the inner wall of the sterilizing filter box body.

[0010] Further, a connecting plate is arranged inside the connecting groove, and a coarse filter frame is arranged at the end of the connecting plate.

[0011] Further, a vibrating machine is installed on the outer wall of the coarse filter frame, and an upper sweeping plate is arranged below the coarse filter frame.

[0012] Further, a connecting frame is arranged at the bottom end of the upper sweeping plate, and a cylinder is installed on the left side of the connecting frame.

[0013] Further, a lower sweeping plate is arranged at the bottom end of the connecting frame, and a fine filter frame is arranged below the lower sweeping plate.

[0014] Further, the shape structure of the lower sweeping plate is in conformity with the shape structure of the upper sweeping plate, and the connecting frame is in a U shape.

[0015] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0016] 1. In the present utility model, the steam generated by heating water through the steam furnace is stored inside the steam chamber, and the steam is conveyed into the sterilizing filter box body by using the heat preservation conveying pipe. Since the pure steam has strong penetrability, proteins and protoplasmic colloids are denatured and coagulated under humid heat conditions, the enzyme system is easily damaged, the steam enters the cells and condenses into water, which can release potential heat to increase the temperature, and further enhances the sterilization power, thereby playing a role in disinfecting and sterilizing the sterilizing filter box body. The connection between the connecting plate and the connecting groove can assemble the coarse filter frame inside the sterilizing filter box body to conduct preliminary screening work on the raw material drug (powder, crystalline).

[0017] 2. In the present utility model, the vibrating machine provides power for the coarse filter frame, enabling the raw material drug to jump and avoiding the blockage of the coarse filter frame. The cylinder drives the lower sweeping plate and the upper sweeping plate to move. The lower sweeping plate can move left and right inside the fine filter frame, driving the raw material drug to move, enabling the raw material drug to pass through the fine filter frame, and conducting more refined filtration treatment on the raw material drug. Description of the Drawings

[0018] Figure 1 This is a schematic diagram of the main three-dimensional structure of a sterilizing filter for raw material drug production of the utility model;

[0019] Figure 2 This is a schematic diagram of the three-dimensional structure of a coarse filter frame and a sterilizing filter box for the production of raw materials of the utility model;

[0020] Figure 3 The utility model is a schematic diagram of the three-dimensional structure of a sterilizing filter cylinder-upper sweeping plate for raw material drug production.

[0021] In the figure: 1. Sterilization and filtration box; 2. Material receiving drawer; 3. Moving plate; 4. Steam furnace; 5. Steam chamber; 6. Insulated conveying pipe; 7. Pipe interface; 8. Sealing cover; 9. Feed inlet; 10. Connecting groove; 11. Connecting plate; 12. Coarse filter frame; 13. Cylinder; 14. Connecting frame; 15. Lower sweeping plate; 16. Fine filter frame; 17. Vibrator; 18. Upper sweeping plate. DETAILED DESCRIPTION

[0022] The following is a further detailed description of the implementation of the present invention in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but cannot be used to limit the scope of the present invention.

[0023] Implementation 1:

[0024] like Figure 1 As shown, a sterilizing filter for raw material drug production includes a sterilizing filter box 1 and a steam furnace 4, a movable plate 3 is arranged on the outer side of the bottom of the sterilizing filter box 1, the steam furnace 4 is installed on the upper end of the movable plate 3, a steam chamber 5 is arranged on the upper end of the steam furnace 4, and a heat preservation conveying pipe 6 is arranged on the upper end of the steam chamber 5, a pipeline interface 7 is arranged on the outer wall of the sterilizing filter box 1, and a sealing cover 8 is installed on the top of the sterilizing filter box 1, and a feed port 9 is opened on the upper end of the sealing cover 8, the steam generated by heating water by the steam furnace 4 is stored in the steam chamber 5, and the steam is conveyed to the inside of the sterilizing filter box 1 by the heat preservation conveying pipe 6, due to the strong penetrability of pure steam, protein and protoplasm colloid are used for denaturation and coagulation under hot and humid conditions, the enzyme system is easily destroyed, the steam enters the cell and condenses into water, can release potential heat to increase the temperature, and further enhances the bactericidal power, thereby playing a role in disinfecting and sterilizing the sterilizing filter box 1.

[0025] Implementation 2:

[0026] like Figure 2 and Figure 3As shown in the figure, a receiving drawer 2 is installed inside the bottom end of the sterilization and filtration box body 1, and a connecting groove 10 is provided on the inner wall of the sterilization and filtration box body 1. Further, a connecting plate 11 is arranged inside the connecting groove 10, and a coarse filter frame 12 is provided at the end of the connecting plate 11. Further, a vibrating machine 17 is installed on the outer wall of the coarse filter frame 12, and an upper material sweeping plate 18 is arranged below the coarse filter frame 12. Further, a connecting frame 14 is provided at the bottom end of the upper material sweeping plate 18, and a cylinder 13 is installed on the left side of the connecting frame 14. Further, a lower material sweeping plate 15 is provided at the bottom end of the connecting frame 14, and a fine filter frame 16 is arranged below the lower material sweeping plate 15. Further, the shape and structure of the lower material sweeping plate 15 are in conformity with the shape and structure of the upper material sweeping plate 18, and the connecting frame 14 is in a U shape. The connection between the connecting plate 11 and the connecting groove 10 can assemble the coarse filter frame 12 inside the sterilization and filtration box body 1 to conduct preliminary screening work on the raw pharmaceutical materials (powders, crystals); the vibrating machine 17 provides power for the coarse filter frame 12, enabling the raw pharmaceutical materials to jump and preventing the coarse filter frame 12 from being blocked. The cylinder 13 drives the lower material sweeping plate 15 and the upper material sweeping plate 18 to move. The lower material sweeping plate 15 can move left and right inside the fine filter frame 16 to drive the raw pharmaceutical materials to move, enabling the raw pharmaceutical materials to pass through the fine filter frame 16 and conducting more refined filtration treatment on the raw pharmaceutical materials.

[0027] Working principle: When the sterilization filter for raw pharmaceutical materials is in use, first, according to Figure 1-Figure 3 , before use, cover the sealing cover 8 to block the feeding port 9, making the sterilization and filtration box body 1 form a sealed space. Connect the heat preservation conveying pipe 6 with the pipeline interface 7, and start the steam furnace 4 to heat the water body. Heating will generate steam, and the steam passes through the heat preservation conveying pipe 6 from the steam cavity 5 into the interior of the sterilization and filtration box body 1. The more the steam accumulates, the higher the temperature inside the sterilization and filtration box body 1. Due to the strong penetrability of pure steam, proteins and protoplasmic colloids are liable to denature and solidify under humid heat conditions, and the enzyme system is easily damaged. The steam enters the cells and condenses into water, which can release latent heat to increase the temperature and further enhance the sterilization power, thus playing a role in disinfecting and sterilizing the sterilization and filtration box body 1. After the sterilization is completed, when the interior of the sterilization and filtration box body 1 is dry, open the feeding port 9 and pour the raw pharmaceutical materials (powders, crystals) into the interior of the sterilization and filtration box body 1 onto the coarse filter frame 12. Use the vibrating machine 17 to provide power for the coarse filter frame 12, enabling the raw pharmaceutical materials to move, pass through the coarse filter frame 12 and fall onto the fine filter frame 16. Start the cylinder 13 to drive the connecting frame 14 to move left and right, enabling the lower material sweeping plate 15 to move left and right inside the fine filter frame 16 to drive the raw pharmaceutical materials to move, enabling the raw pharmaceutical materials to pass through the fine filter frame 16 and conducting more refined filtration treatment on the raw pharmaceutical materials. The upper material sweeping plate 18 can scrape off the raw pharmaceutical materials accumulated on the bottom surface of the coarse filter frame 12. The processed raw pharmaceutical materials will fall from the fine filter frame 16 into the receiving drawer 2, and thus the sterilization and filtration work can be completed.

[0028] The embodiments of the present invention are provided for the purpose of illustration and description, and are not intended to be exhaustive or to limit the present invention to the disclosed forms. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiments are selected and described to better illustrate the principles and practical applications of the present invention, and to enable those of ordinary skill in the art to understand the present invention and thereby design various embodiments with various modifications suitable for specific uses.

Claims

1. A sterilizing filter for the production of bulk drugs, comprising a sterilizing filter housing (1) and a steam oven (4), characterized in that: A moving plate (3) is provided on the outer side of the bottom of the sterilization and filtration box body (1). The steam furnace (4) is installed at the upper end of the moving plate (3). A steam chamber (5) is provided at the upper end of the steam furnace (4), and a heat preservation conveying pipe (6) is provided at the upper end of the steam chamber (5). A pipeline interface (7) is provided on the outer wall of the sterilization and filtration box body (1), and a sealing cover (8) is installed at the top end of the sterilization and filtration box body (1). A feeding port (9) is opened at the upper end of the sealing cover (8).

2. A sterilizing filter for the production of bulk drugs according to claim 1, characterized in that: A material receiving drawer (2) is installed inside the bottom end of the sterilization and filtration box body (1), and a connecting groove (10) is provided on the inner wall of the sterilization and filtration box body (1).

3. A sterilizing filter for bulk drug production according to claim 2, characterized in that: A connecting plate (11) is arranged inside the connecting groove (10), and a coarse filter frame (12) is provided at the end of the connecting plate (11).

4. A sterilizing filter for bulk drug production according to claim 3, characterized in that: A vibrator (17) is installed on the outer wall of the coarse filter frame (12), and an upper sweeping plate (18) is arranged below the coarse filter frame (12).

5. A sterilizing filter for the production of bulk drugs according to claim 4, characterized in that: A connecting frame (14) is provided at the bottom end of the upper sweeping plate (18), and a cylinder (13) is installed on the left side of the connecting frame (14).

6. A sterilizing filter for bulk drug production according to claim 5, characterized in that: A lower sweeping plate (15) is provided at the bottom end of the connecting frame (14), and a fine filter frame (16) is arranged below the lower sweeping plate (15).

7. A sterilizing filter for the production of bulk drugs according to claim 6, characterized in that: The shape and structure of the lower sweeping plate (15) are in conformity with the shape and structure of the upper sweeping plate (18), and the connecting frame (14) is in a U shape.

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