Efficient continuous production device for medical intermediates

Abstract

The utility model relates to the technical field of medical intermediates, and discloses an efficient continuous production device for medical intermediates, which comprises a reaction kettle body, a feed inlet is fixedly connected above the reaction kettle body, a cleaning component is arranged on the right side of the reaction kettle body, and a lifting component is arranged on the front side of the cleaning component. The cleaning assembly comprises a lifting rod, the lifting rod is fixedly connected with the right side of the reaction kettle body, the outer surface of the lifting rod is movably sleeved with a lifting sleeve, the right side of the lifting sleeve is fixedly connected with a connecting piece, a flushing assembly is arranged below the connecting piece, and the flushing assembly comprises a rotating seat; and the rotating seat penetrates through and is rotationally connected with the lower part of the connecting sheet. The lifting assembly rotates to drive the cleaning assembly to descend, so that the flushing assembly extends into the reaction kettle body from the feeding opening, the flushing assembly is not affected when the driving assembly drives the cleaning assembly to rotate, and the effect of flushing while cleaning the inner wall of the reaction kettle body is achieved.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmaceutical intermediates, in particular to a high-efficiency continuous production device for pharmaceutical intermediates. Background Art

[0002] The so-called pharmaceutical intermediates are actually some chemical raw materials or chemical products used in the process of drug synthesis. This kind of chemical product does not require a drug production license and can be produced in an ordinary chemical plant. As long as it reaches a certain level, it can be used in drug synthesis.

[0003] For example, the Chinese patent publication number CN218359240U, "High-efficiency continuous production device for pharmaceutical intermediates", discloses a high-efficiency continuous production device for pharmaceutical intermediates, which relates to the technical field of pharmaceutical intermediate production, including a bracket, a reactor body arranged on the bracket, a rotating cleaning member arranged in the reactor body, the cleaning member including a scraper slidingly abutting against the inner side wall of the reactor body, the cleaning member also including a driving member driving the scraper to reciprocate vertically, a first brush bar is installed on the lower surface of the scraper, the first brush bar slidingly abutting against the inner bottom wall of the reactor body, the first brush bar is perpendicular to the central axis of the reactor body, thereby realizing automatic cleaning of the inner wall of the reactor body, and reducing the production time of the pharmaceutical intermediates to a certain extent when carrying out continuous production of multiple pharmaceutical intermediates.

[0004] However, in actual use, the reactor body is cleaned by a cleaning piece after production is completed. When some pharmaceutical intermediates stick to the inner wall of the reactor body, it is not convenient to speed up the cleaning of the reactor body by flushing and cleaning at the same time, and it is not convenient to enhance the cleaning efficiency of the reactor body in an emergency. Utility Model Content

[0005] 1. Technical issues to be solved

[0006] In view of the deficiencies of the prior art, the utility model provides a highly efficient continuous production device for pharmaceutical intermediates.

[0007] (II) Technical solution

[0008] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an efficient continuous production device for pharmaceutical intermediates, comprising a reactor body, a feed inlet is fixedly connected to the top of the reactor body, a cleaning component is arranged on the right side of the reactor body, and a lifting component is arranged on the front of the cleaning component;

[0009] The cleaning assembly includes a lifting rod, which is fixedly connected to the right side of the reactor body. A lifting sleeve is provided on the outer surface of the lifting rod. A connecting piece is fixedly connected to the right side of the lifting sleeve. A flushing assembly is provided below the connecting piece. The flushing assembly includes a rotating seat, which passes through and is rotatably connected to the bottom of the connecting piece. A pipe is fixedly connected to the bottom of the rotating seat. A nozzle is fixedly connected to the left side of the pipe. A driving assembly is provided above the reactor body.

[0010] Preferably, the lifting assembly includes a first motor, which is fixedly connected to the right side of the reactor body, and the output end of the first motor is fixedly connected to a screw via a coupling. A lifting plate is provided on the threaded sleeve on the outer surface of the screw, and the lifting plate is fixedly connected to the front side of the lifting sleeve. A top plate is rotatably connected above the screw, and the top plate is fixedly connected to the top of the lifting rod.

[0011] Preferably, the flushing assembly further comprises a first gear, the first gear is fixedly connected to the outer surface of the rotating seat, and a rotating connector is rotatably connected above the rotating seat.

[0012] Preferably, the driving assembly includes a motor base, which is fixedly connected to the top of the reactor body, a second motor is fixedly installed on the right side of the motor base, an output end of the second motor is fixedly connected to a rotating rod via a coupling, the rotating rod passes through the top of the reactor body and is rotatably connected, a stirring rod is fixedly connected to the outer surface of the rotating rod, and cleaning assemblies are arranged on the left and right sides of the rotating rod.

[0013] Preferably, the cleaning assembly comprises a connecting strip, the connecting strip is fixedly connected to the lower end of the rotating rod, the left and right ends of the connecting strip are fixedly connected with cleaning strips, and the cleaning strip is movably fitted to the inner surface of the reactor body.

[0014] Preferably, a supporting leg is fixedly connected below the reactor body, and a discharge valve is fixedly connected below the reactor body.

[0015] Preferably, the driving assembly further comprises a second gear, and the second gear is adapted to match the first gear.

[0016] (III) Beneficial effects

[0017] Compared with the prior art, the utility model provides an efficient continuous production device for pharmaceutical intermediates, which has the following beneficial effects:

[0018] 1. The efficient continuous production device for pharmaceutical intermediates drives the cleaning component to descend by rotating the lifting component so that the flushing component extends from the feed port into the reactor body. The driving component drives the cleaning component to rotate without affecting the flushing component, which facilitates flushing while cleaning the inner wall of the reactor body.

[0019] 2. The efficient continuous production device for pharmaceutical intermediates, through the descent of the cleaning component, the first gear on the flushing component will mesh with the second gear on the driving component. At this time, the driving component drives the cleaning component to rotate and at the same time drives the flushing component to rotate, thereby achieving the effect of rotating water spray flushing. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0021] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0022] Figure 2 This is a cross-sectional view of the overall structure of the utility model;

[0023] Figure 3 For this utility model Figure 1 A schematic diagram of the enlarged structure in the middle.

[0024] In the figure: 1. Reactor body; 2. Feed inlet; 3. Cleaning assembly; 301. Lifting rod; 302. Lifting sleeve; 303. Connecting plate; 4. Lifting assembly; 401. First motor; 402. Screw; 403. Lifting plate; 404. Top plate; 5. Flushing assembly; 501. Rotating seat; 502. Pipeline; 503. Nozzle; 504. First gear; 505. Rotating connector; 6. Driving assembly; 601. Motor base; 602. Second motor; 603. Rotating rod; 604. Stirring rod; 605. Second gear; 7. Cleaning assembly; 701. Connecting strip; 702. Cleaning strip; 8. Support leg; 9. Discharge valve. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0026] Example 1

[0027] like Figure 1-3As shown, the utility model provides an efficient continuous production device for pharmaceutical intermediates, including a reactor body 1, a feed port 2 is fixedly connected above the reactor body 1, a support leg 8 is fixedly connected below the reactor body 1, and the number of the support legs 8 is four. A discharge valve 9 is fixedly connected below the reactor body 1, and a cleaning component 3 is arranged on the right side of the reactor body 1. The cleaning component 3 includes a lifting rod 301, the lifting rod 301 is fixedly connected to the right side of the reactor body 1, and the lifting rod 301 is connected to the right side of the reactor body 1 through a connecting block. A lifting sleeve 302 is movably sleeved on the outer surface of the lifting rod 301, and a connecting piece 303 is fixedly connected to the right side of the lifting sleeve 302. A flushing component 5 is arranged below the connecting piece 303, and the flushing component 5 It includes a rotating seat 501, which penetrates and is rotatably connected to the bottom of the connecting piece 303. A pipe 502 is fixedly connected to the bottom of the rotating seat 501, and a nozzle 503 is fixedly connected to the left side of the pipe 502. A driving component 6 is arranged above the reactor body 1, and a lifting component 4 is arranged on the front of the cleaning component 3. The lifting component 4 includes a first motor 401, which is fixedly connected to the right side of the reactor body 1. A screw 402 is fixedly connected to the output end of the first motor 401 through a coupling. A lifting piece 403 is provided on the threaded sleeve on the outer surface of the screw 402. The lifting piece 403 is fixedly connected to the front of the lifting sleeve 302. A top piece 404 is rotatably connected to the top of the screw 402, and the top piece 404 is fixedly connected to the top of the lifting rod 301.

[0028] In this embodiment, the cleaning component 3 is driven downward by the rotation of the lifting component 4 so that the flushing component 5 extends from the feed port 2 into the reactor body 1. When the driving component 6 drives the cleaning component 7 to rotate, it will not affect the flushing component 5, which facilitates flushing while cleaning the inner wall of the reactor body 1.

[0029] Example 2

[0030] like Figure 1-3As shown, on the basis of Example 1, the utility model provides a technical solution: preferably, the flushing component 5 also includes a first gear 504, the first gear 504 is fixedly connected to the outer surface of the rotating seat 501, and a rotating connector 505 is rotatably connected above the rotating seat 501. The rotating connector 505 is used to connect the water pipe and enable the connection to rotate at the same time. The rotating connector 505, the rotating seat 501 and the pipeline 502 are interconnected. The driving component 6 includes a motor base 601, the motor base 601 is fixedly connected to the top of the reactor body 1, and a second motor 602 is fixedly installed on the right side of the motor base 601. The output end of the second motor 602 is fixedly connected to the rotating Rod 603, rotating rod 603 passes through the top of the reactor body 1 and is rotatably connected, a stirring rod 604 is fixedly connected to the outer surface of the rotating rod 603, and the stirring rod 604 will not hit the pipe 502 and the nozzle 503 when rotating and stirring, and cleaning components 7 are arranged on the left and right sides of the rotating rod 603, and the cleaning components 7 include a connecting strip 701, and the connecting strip 701 is fixedly connected to the lower end of the rotating rod 603, and the left and right ends of the connecting strip 701 are fixedly connected to cleaning strips 702, and the cleaning strip 702 is movably fitted with the inner surface of the reactor body 1, and the driving component 6 also includes a second gear 605, and the second gear 605 is adapted to the first gear 504, and when the first gear 504 descends, it will mesh with the second gear 605.

[0031] In this embodiment, by the descent of the cleaning component 3, the first gear 504 on the flushing component 5 will engage with the second gear 605 on the driving component 6. At this time, the driving component 6 drives the cleaning component 7 to rotate and at the same time drives the flushing component 5 to rotate, thereby achieving the effect of rotating water spray flushing.

[0032] The following is a detailed description of the working principle of the efficient continuous production device for pharmaceutical intermediates.

[0033] like Figure 1-3As shown, when in use, the pharmaceutical intermediate is prepared through the reactor body 1. After the preparation is completed, the pharmaceutical intermediate is taken out through the discharge valve 9. At this time, the first motor 401 is started, and the screw 402 is driven by the first motor 401 to lower the lifting plate 403, thereby driving the lifting sleeve 302 to descend on the lifting rod 301. The lowering of the lifting sleeve 302 drives the connecting piece 303 to make the pipe 502 and the nozzle 503 extend from the feed port 2 above the reactor body 1. At this time, the external water pipe is connected to the rotating connector 505, and the water will reach the pipe 502 through the rotating seat 501 and spray out from the nozzle 503, so as to achieve the effect of spraying water to clean the reactor body 1. When the connecting piece 303 After the pipe 502 and the nozzle 503 are lowered to extend from the feed port 2 above the reactor body 1, the first gear 504 on the rotating seat 501 will mesh with the second gear 605. At this time, the second motor 602 is started to drive the rotating rod 603 to rotate, and then the connecting strip 701 is driven to rotate to make the cleaning strip 702 scrape the inner surface of the reactor body 1 to achieve the cleaning effect. As the rotating rod 603 rotates, the second gear 605 is driven to rotate, and the first gear 504 is driven by the second gear 605 to rotate the rotating seat 501. The rotating seat 501 rotates to drive the pipe 502 and the nozzle 503 to rotate and spray water on the inner surface of the reactor body 1, so as to facilitate water spraying and flushing.

Claims

1. An efficient continuous production device for pharmaceutical intermediates, comprising a reactor body (1), characterized in that: A feed port (2) is fixedly connected to the top of the reactor body (1); a cleaning component (3) is arranged on the right side of the reactor body (1); and a lifting component (4) is arranged on the front side of the cleaning component (3); The cleaning assembly (3) comprises a lifting rod (301), the lifting rod (301) is fixedly connected to the right side of the reactor body (1), a lifting sleeve (302) is movably sleeved on the outer surface of the lifting rod (301), a connecting piece (303) is fixedly connected to the right side of the lifting sleeve (302), a flushing assembly (5) is arranged below the connecting piece (303), the flushing assembly (5) comprises a rotating seat (501), the rotating seat (501) penetrates and is rotatably connected to the bottom of the connecting piece (303), a pipe (502) is fixedly connected to the bottom of the rotating seat (501), a nozzle (503) is fixedly connected to the left side of the pipe (502), and a driving assembly (6) is arranged above the reactor body (1).

2. The efficient continuous production device for pharmaceutical intermediates according to claim 1, characterized in that: The lifting assembly (4) comprises a first motor (401), the first motor (401) is fixedly connected to the right side of the reactor body (1), the output end of the first motor (401) is fixedly connected to a screw rod (402) via a coupling, a lifting plate (403) is threadedly sleeved on the outer surface of the screw rod (402), the lifting plate (403) is fixedly connected to the front of the lifting sleeve (302), a top plate (404) is rotatably connected to the top of the screw rod (402), and the top plate (404) is fixedly connected to the top of the lifting rod (301).

3. The efficient continuous production device for pharmaceutical intermediates according to claim 1, characterized in that: The flushing assembly (5) further comprises a first gear (504), wherein the first gear (504) is fixedly connected to the outer surface of the rotating seat (501), and a rotating connecting member (505) is rotatably connected above the rotating seat (501).

4. The efficient continuous production device for pharmaceutical intermediates according to claim 1, characterized in that: The driving assembly (6) comprises a motor base (601), the motor base (601) is fixedly connected to the top of the reactor body (1), a second motor (602) is fixedly installed on the right side of the motor base (601), an output end of the second motor (602) is fixedly connected to a rotating rod (603) via a coupling, the rotating rod (603) passes through the top of the reactor body (1) and is rotatably connected, a stirring rod (604) is fixedly connected to the outer surface of the rotating rod (603), and cleaning assemblies (7) are arranged on the left and right sides of the rotating rod (603).

5. The efficient continuous production device for pharmaceutical intermediates according to claim 4, characterized in that: The cleaning assembly (7) comprises a connecting strip (701), wherein the connecting strip (701) is fixedly connected to the lower end of the rotating rod (603), and cleaning strips (702) are fixedly connected to the left and right ends of the connecting strip (701), and the cleaning strip (702) is movably fitted to the inner surface of the reactor body (1).

6. The efficient continuous production device for pharmaceutical intermediates according to claim 1, characterized in that: A support leg (8) is fixedly connected to the bottom of the reactor body (1), and a discharge valve (9) is fixedly connected to the bottom of the reactor body (1).

7. The efficient continuous production device for pharmaceutical intermediates according to claim 4, characterized in that: The driving assembly (6) further comprises a second gear (605), wherein the second gear (605) is adapted to match the first gear (504).

Images