Peripheral blood direct sampling mechanism and measuring system
Through the design of the peripheral blood, directly entering the sample institution, using the combination of blood vessels and inlet components to solve the problem of inconvenience of the existing peripheral blood detection operation, and realize the rapid, safe and efficient detection of peripheral blood.
Patent Information
- Application Number
- CN202420792770.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-16
- Publication Date
- 2025-01-24
- Estimated Expiration
- 2034-04-16
AI Technical Summary
The existing peripheral blood detection operation is inconvenient, and requires mixed blood evenly. The blood volume is large and easy to contaminate, and the operation is complicated. The blood collection process requires multiple devices and tweezers to operate.
Design a kind of peripheral blood directly into the sample institution, use the internal collection channel of the vascular pipe body, directly hold the blood vessels to collect blood through the hand -holding part. After the collection is completed analyze.
It realizes the convenient and fast collection and detection of peripheral blood, simplifies the operation process, reduces the risk of contamination, and improves the safety and effectiveness of detection.
Smart Images

Figure CN222394070U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of blood testing equipment, in particular to a peripheral blood direct sampling mechanism and a measuring system. Background Art
[0002] At present, when testing peripheral blood, firstly, the peripheral blood needs to be mixed, which requires a large amount of blood and may cause uneven mixing; secondly, the current peripheral blood test requires a lot of equipment, the process of making the test sample is complicated and easy to cause contamination, and it is also necessary to use tweezers to clamp the disposable capillary blood collection tube, and then install the capillary tube on the peripheral blood device of the instrument. Therefore, the current peripheral blood test operation is inconvenient and the operation requirements are relatively high. Utility Model Content
[0003] The main purpose of the utility model is to provide a peripheral blood direct sampling mechanism, aiming to solve the current technical problem of inconvenient peripheral blood sampling and testing operation.
[0004] In order to achieve the above-mentioned purpose, the peripheral blood direct sampling mechanism proposed in the utility model comprises:
[0005] A blood collection tube, the blood collection tube comprising a tube body and a hand-held part, the tube body having a collection channel for collecting blood to be tested, the hand-held part being arranged near one end of the tube body and protruding from the outer periphery of the tube body; and
[0006] An injection assembly, wherein the injection assembly is provided with a sample outlet and a reagent channel for conveying a diluent, the reagent channel includes a first conveying channel, the injection assembly includes a shell, a mounting seat and an end cover, wherein the shell is provided with a sliding cavity, the mounting seat is slidably arranged in the sliding cavity, the mounting seat is provided with a receiving cavity for placing the blood collection tube and a mixing cavity connected to the receiving cavity, the mixing cavity is also connected to the sample outlet, the end cover is used to be snap-fitted and connected to the shell, the sample outlet is provided at one end of the mounting seat away from the end cover, the first conveying channel is provided at the end cover, when the end cover is snap-fitted to the shell and moves toward the sample outlet, the first conveying channel is connected to the collection channel, the diluent flows into the collection channel from the first conveying channel, and drives the blood to be tested to flow into the mixing cavity and be discharged through the sample outlet.
[0007] Optionally, the tube body includes a supporting portion and a connecting portion, the hand-held portion is arranged on the outer periphery of the connecting portion, the supporting portion is conically arranged, the inner wall contour of the accommodating cavity is matched with the outer wall contour of the blood collection tube, the inner wall of the accommodating cavity is provided with a supporting member, the supporting member is used to seal and contact the supporting portion, and form a conveying gap between the outer peripheral surface of the supporting portion and the inner wall of the accommodating cavity, the conveying gap is connected with the mixing chamber, the reagent channel also includes a second conveying channel, the second conveying channel is opened on the mounting seat, and the second conveying channel is connected with the conveying gap, the second conveying channel conveys the diluent into the conveying gap and further flows into the mixing chamber.
[0008] Optionally, a fixing hole connected to the collection channel is formed at one end of the connecting portion away from the supporting portion, and the end cover is provided with a sealing cap, and the sealing cap forms a first outlet, and the first outlet is connected to the first conveying channel. When the end cover is buckled into the shell and moves toward the sample outlet, the sealing cap is sealingly inserted into the fixing hole, and the first outlet is cooperatively connected to the fixing hole.
[0009] Optionally, the direct peripheral blood sampling mechanism also includes an inner slider, the mounting seat is provided with a first groove, the inner slider is slidably disposed in the first groove, and a first reset member is also provided between the inner slider and the first groove, the first reset member is used to drive the blood collection tube to move away from the mounting seat, and when the blood collection tube is placed in the accommodating cavity, the hand-held part is supported on the inner slider.
[0010] Optionally, the housing comprises a base and a sliding seat, the end cover is used to buckle and connect the sliding seat, the sliding seat has an initial position away from the base and an injection position close to the base, and the sliding seat slides toward the base so that the sliding seat switches from the initial position to the injection position;
[0011] The end cover is buckled and connected to the sliding seat, and when the sliding seat switches from the initial position to the injection position, the end cover drives the blood collection tube and the mounting seat to slide towards the direction close to the base.
[0012] Optionally, the direct peripheral blood sampling mechanism also includes a first detection member and a second detection member respectively arranged on the base, the end cover is provided with a locking hook, and the base is provided with a locking tongue. When the sliding seat is in the injection position, the locking hook is locked and connected to the locking tongue and triggers the first detection member; the base is provided with an avoidance hole connected to the sliding cavity, and the mounting seat is connected with a trigger member, and the trigger member extends out of the avoidance hole. When the sliding seat is in the injection position, the mounting seat slides in a direction away from the end cover and drives the trigger member to trigger the second detection member.
[0013] Optionally, a second reset member is provided between the mounting seat and the base, the second reset member is provided at an end of the mounting seat away from the end cover, and the second reset member is also connected to the base, and when the sliding seat is switched from the injection position to the initial position, the second reset member is used to drive the mounting seat to move toward the end cover; a third reset member is provided between the base and the sliding seat, and when the sliding seat is switched from the injection position to the initial position, the third reset member is used to drive the sliding seat to move in a direction away from the base.
[0014] Optionally, the base is provided with a rotating shaft, the lock tongue and the base are rotatably connected via the rotating shaft, the lock tongue has a driving end and a reset end, and the driving end and the reset end are respectively located on both sides of the rotating shaft, the base is also provided with a connecting column, the reset end is connected to a fourth reset member, and the fourth reset member is also connected to the connecting column.
[0015] Optionally, the base is provided with a guide seat, the sliding seat is connected to a guide column, and the guide column is slidably connected to the guide seat.
[0016] The utility model also provides a measuring system, comprising an analysis mechanism, a mixing tank, a diluent tank and a sampling mechanism, wherein the sampling mechanism is the peripheral blood direct sampling mechanism as described above;
[0017] The sample injection mechanism is arranged between the mixing tank and the diluent tank, and a second valve is arranged between the sample injection mechanism and the mixing tank;
[0018] The diluent tank is used to hold a diluent, and the diluent tank is connected to a driving member, and the driving member is used to add a diluent into the diluent tank, and the diluent flows into the injection mechanism through the diluent tank, and is discharged into the mixing tank through the sample outlet of the injection mechanism, and the diluent tank is connected to an electrode, and the electrode is used to detect the liquid level of the diluent in the diluent tank;
[0019] The mixing pool is connected to the analysis mechanism, and a first valve is provided between the mixing pool and the analysis mechanism. The mixing pool is also connected to a buffer gas tank, and the buffer gas tank is connected to a first drive pump. A fourth valve is provided between the first drive pump and the buffer gas tank. The mixing pool is also connected to a second drive pump, and a third valve is provided between the second drive pump and the mixing pool.
[0020] The technical solution of the utility model adopts a collection channel in the tube body of the blood collection tube to collect the blood to be tested, and the blood is collected by directly holding the blood collection tube through the handheld part, so that peripheral blood can be collected conveniently and quickly. After the collection is completed, the blood collection tube does not need to be mixed, and is directly placed in the sampling assembly. After the blood sample is transported, it is directly entered into the blood cell analyzer for measurement and analysis. The detection operation is simple, safe and effective. Specifically, the sampling assembly is provided with a sample outlet and a reagent channel for conveying a diluent. After the end cover is buckled into the shell, the end cover is driven to move, so that the first conveying channel of the end cover is connected with the collection channel, so that the diluent flows from the first conveying channel into the collection channel, and drives the blood to be tested in the collection channel into the mixing chamber together, and is discharged through the sample outlet for the next step of analysis and measurement. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying creative work.
[0022] Figure 1 This is a schematic structural diagram of an embodiment of the peripheral blood direct sampling mechanism of the utility model in an open state end cover;
[0023] Figure 2 It is a cross-sectional structural diagram of an embodiment of the peripheral blood direct sampling mechanism of the utility model in an open state of the end cover;
[0024] Figure 3 It is a schematic structural diagram of the end cover in the buckled state of the embodiment of the peripheral blood direct sampling mechanism of the utility model;
[0025] Figure 4 It is a cross-sectional structural schematic diagram of the end cover buckled state of the embodiment of the peripheral blood direct sampling mechanism of the utility model;
[0026] Figure 5 Another cross-sectional structural schematic diagram of the end cover of the direct peripheral blood sampling mechanism embodiment of the utility model in a buckled state;
[0027] Figure 6 It is a schematic diagram of an exploded structure of an embodiment of the peripheral blood direct sampling mechanism of the utility model in an open end cover state;
[0028] Figure 7 Another exploded structural schematic diagram of the embodiment of the peripheral blood direct sampling mechanism of the utility model in the state where the end cover is opened;
[0029] Figure 8 This is a schematic diagram of the liquid circuit structure of an embodiment of the detection system of the utility model.
[0030] Description of Figure Numbers:
[0031]
[0032]
[0033] The realization of the purpose, functional features and advantages of the utility model will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION
[0034] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0035] It should be noted that all directional indications (such as up, down, left, right, front, back...) in the embodiments of the present invention are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.
[0036] In the present invention, unless otherwise clearly specified and limited, the terms "connection", "fixation", etc. should be understood in a broad sense. For example, "fixation" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0037] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the utility model, the descriptions of "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the meaning of "and / or" appearing in the full text includes three parallel schemes. Taking "A and / or B" as an example, it includes scheme A, or scheme B, or a scheme that satisfies both A and B. In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the ability of ordinary technicians in this field to implement. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the utility model.
[0038] The utility model provides a peripheral blood direct sampling mechanism.
[0039] In the prior art, when testing peripheral blood, firstly, the peripheral blood needs to be mixed, which requires a large amount of blood and may cause uneven mixing; secondly, the current peripheral blood test requires a large number of devices, the process of making the test sample is complicated and easy to cause contamination, and it is also necessary to use tweezers to clamp the disposable capillary blood collection tube, and then install the capillary tube on the peripheral blood device of the instrument. Therefore, the current peripheral blood test operation is inconvenient and the operation requirements are relatively high.
[0040] In order to solve the above technical problems, the technical solution of the utility model adopts a collection channel in the tube body of the blood collection tube to collect the blood to be tested, and the blood is collected by directly holding the blood collection tube through the handheld part, so that peripheral blood can be collected conveniently and quickly. After the collection is completed, the blood collection tube does not need to be mixed, and is directly placed in the sampling assembly. After the blood sample is transported, it is directly entered into the blood cell analyzer for measurement and analysis. The detection operation is simple, safe and effective. Specifically, the sampling assembly is provided with a sample outlet and a reagent channel for conveying a diluent. After the end cover is buckled into the shell, the end cover is driven to move, so that the first conveying channel of the end cover is connected with the collection channel, so that the diluent flows from the first conveying channel into the collection channel, and drives the blood to be tested in the collection channel into the mixing chamber together, and is discharged through the sample outlet for the next step of analysis and measurement.
[0041] The above technical solution is described in detail below with reference to the accompanying drawings.
[0042] In the embodiment of the present utility model, Figure 1-Figure 7As shown, the direct peripheral blood sampling mechanism includes: a blood collection tube 100 and a sampling assembly 200, wherein the blood collection tube 100 includes a tube body 110 and a hand-held part 120, the tube body 110 penetrates and opens a collection channel 140 for collecting blood to be tested, and the hand-held part 120 is arranged near one end of the tube body 110 and protrudes from the outer periphery of the tube body 110.
[0043] It should be noted that the user can complete the collection of blood to be tested by holding the handheld portion 120 of the blood collection tube 100 and using the collection channel 140, wherein the collection channel 140 is a capillary channel, which can refer to the channel of the existing capillary blood collection tube 100 for collecting peripheral blood. In this embodiment, the blood to be tested is peripheral blood, and the peripheral blood can be automatically sucked into the collection channel 140. Therefore, the blood collection tube 100 can be directly held by the hand to complete the collection of peripheral blood, without the need to use tweezers or the like to clamp the blood, which is simple and convenient.
[0044] The sample injection assembly 200 is provided with a sample outlet 233 and a reagent channel for conveying a diluent, the reagent channel includes a first conveying channel 241, and the sample injection assembly 200 includes a shell, a mounting seat 230 and an end cover 240, wherein the shell is provided with a sliding cavity, the mounting seat 230 is slidably arranged in the sliding cavity, the mounting seat 230 is provided with a receiving cavity 231 for placing the blood collection tube 100 and a mixing cavity 232 connected to the receiving cavity 231, the mixing cavity 232 is also connected to the sample outlet 233, the end cover 240 is used for buckling and connecting the shell, the sample outlet 233 is provided at one end of the mounting seat 230 away from the end cover 240, the first conveying channel 241 is provided at the end cover 240, when the end cover 240 is buckled to the shell and moves toward the sample outlet 233, the first conveying channel 241 is connected with the collection channel 140, the diluent flows into the collection channel 140 from the first conveying channel 241, and drives the blood to be tested to flow into the mixing cavity 232 and be discharged through the sample outlet 233.
[0045] In this embodiment, the mixing chamber 232 is located between the sample outlet 233 and the accommodating chamber 231. After the blood collection tube 100 is placed in the accommodating chamber 231, the end of the blood collection tube 100 away from the handheld part 120 is at least partially located in the mixing chamber 232. In this way, the end cap 240 and the shell are driven to move toward the sample outlet 233, so that the end cap 240 contacts the blood collection tube 100 and the first delivery channel 241 is connected to the collection channel 140. After the diluent enters the blood collection tube 100, the diluent drives the blood to be tested in the blood collection tube 100 to directly enter the mixing chamber 232, reducing the flow of the blood to be tested into the accommodating chamber 231, improving the utilization rate of the blood, and the diluent and the blood to be tested are discharged from the sample assembly through the sample outlet 233, and enter the next step. The mounting seat 230 is slidably connected to the shell, and one side of the end cap 240 is rotatably connected to the shell. After the blood collection tube 100 is placed in the accommodating channel cavity, the end cap 240 is flipped and snapped on the shell, and the blood collection tube 100 is sealed in the shell.
[0046] Optionally, the tube body 110 includes a supporting portion 111 and a connecting portion 112, the hand-held portion 120 is arranged on the outer periphery of the connecting portion 112, the supporting portion 111 is conically arranged, the inner wall contour of the accommodating cavity 231 is matched with the outer wall contour of the blood collection tube 100, and a supporting member 300 is arranged on the inner wall of the accommodating cavity 231. The supporting member 300 is used to seal and contact the supporting portion 111, and form a conveying gap 310 between the outer peripheral surface of the supporting portion 111 and the inner wall of the accommodating cavity 231, and the conveying gap 310 is connected with the mixing cavity 232. The reagent channel also includes a second conveying channel 234, and the second conveying channel 234 is opened on the mounting seat 230, and the second conveying channel 234 is connected with the conveying gap 310. The second conveying channel 234 conveys the diluent into the conveying gap 310 and further flows into the mixing cavity 232.
[0047] In the specific implementation process, the support portion 111 is set in a conical shape, and the corresponding part of the inner wall of the accommodating chamber 231 is also set in a conical shape that matches the support portion 111. When the diluent drives the blood to be tested into the mixing chamber 232, part of the diluent or the blood to be tested may flow into the accommodating chamber 231, thereby contaminating the accommodating chamber 231 or causing waste of the blood to be tested. In this embodiment, by setting a support member 300 on the inner wall of the accommodating chamber 231, the support portion 111 of the blood sampling tube 100 is supported on the support member 300, so that a conveying gap 310 is formed between the outer wall of the blood sampling tube 100 and part of the inner wall of the accommodating chamber 231, and by setting a second conveying channel 234 for conveying the diluent, the diluent also enters the conveying gap 310 through the second conveying channel 234, and is further conveyed to the mixing chamber 232, thereby preventing the blood to be tested from entering the accommodating chamber 231. The support part 111 is sealed and connected to the outer wall of the blood collection tube 100, and the inner wall of the accommodating chamber 231 is provided with a support groove, and the support member 300 is made of silicone or rubber and installed in the support groove. The support member 300 is an O-ring structure, surrounding the circumference of the blood collection tube 100 and sealingly connected to the blood collection tube 100.
[0048] Further, the end of the connecting portion 112 away from the supporting portion 111 is provided with a fixing hole 130 connected to the collection channel 140, and the end cover 240 is provided with a sealing cap 242, and the sealing cap 242 is provided with a first outlet 243, and the first outlet 243 is connected to the first delivery channel 241. When the end cover 240 is buckled to the housing and moves toward the sample outlet 233, the sealing cap 242 is sealed and inserted into the fixing hole 130, and the first outlet 243 is connected with the fixing hole 130. In this embodiment, the sealing cap 242 has a blocking protrusion, and the first reagent outlet is provided at the blocking protrusion. When the end cover 240 covers the accommodating cavity 231, the blocking protrusion is inserted into the fixing hole 130 and is sealed and connected with the inner wall of the fixing hole 130.
[0049] When the blood sampling tube 100 is placed in the accommodating chamber 231, the space occupied in the accommodating chamber 231 will cause the gas in the accommodating chamber 231 to flow. In order to prevent the blood to be tested in the blood sampling tube 100 from overflowing due to the air flow in the accommodating chamber 231, in this embodiment, optionally, the peripheral blood direct sampling mechanism also includes an inner slider 250, the mounting seat 230 is provided with a first groove, the inner slider 250 is slidably arranged in the first groove, and a first reset member is further provided between the inner slider 250 and the first groove, the first reset member is used to drive the blood sampling tube 100 to move in a direction away from the mounting seat 230, and when the blood sampling tube 100 is placed in the accommodating chamber 231, the hand-held part 120 is supported on the inner slider 250.
[0050] In the specific implementation process, the end of the mounting seat 230 away from the sample outlet 233 is recessed to form a first groove, and the first groove is located at the outer periphery of the opening at one end of the accommodating chamber 231. The inner slider 250 is slidably connected in the first groove to support the blood collection tube 100. Specifically, a step surface is formed between the hand-held portion 120 and the tube body 110 of the blood collection tube 100, and the step surface is supported on the inner slider 250. In this embodiment, when the blood collection tube 100 is placed in the accommodating chamber 231, it is supported on the inner slider 250. At this time, there is a gap between the blood collection tube 100 and the inner wall of the accommodating chamber 231 for gas circulation, so as to prevent the gas in the accommodating chamber 231 from entering the blood collection tube 100 and causing the blood to be tested to overflow. Further, in this embodiment, the inner slider 250 is provided with a limiting hole, and a limiting column is protruding from the inner wall of the first groove. When the inner slider 250 slides, the limiting column cooperates with the limiting hole to prevent the inner slider 250 from sliding off.
[0051] When the end cap 240 and the housing are driven to slide, the first reset member is a compression spring, one end of which is connected to the inner slider 250, and the other end is connected to the inner bottom wall of the first groove. The blood collection tube 100 presses the inner slider 250 to slide and compresses the first reset member. It can be understood that after the pressure of the blood collection tube 100 is released, the first reset member drives the inner slider 250 to reset under the elastic action, and it is also convenient to take out the blood collection tube 100. In addition, in this embodiment, when the end cap 240 and the housing are driven to slide, the end cap 240 first contacts and seals the fixing hole 130, and then blocks the blood collection channel. When the end cap 240 and the housing slide further, since the blood collection channel has been sealed, even if the gas changes and flows, it will not cause the blood to be tested to overflow, thereby ensuring the utilization rate of the blood to be tested.
[0052] Optionally, the housing includes a base 210 and a sliding base 220, the end cover 240 is used to buckle and connect the sliding base 220, the sliding base 220 has an initial position away from the base 210 and an injection position close to the base 210, and the sliding base 220 slides toward the base 210 so that the sliding base 220 switches from the initial position to the injection position;
[0053] The end cover 240 is buckled and connected to the sliding seat 220 , and when the sliding seat 220 switches from the initial position to the injection position, the end cover 240 drives the blood collection tube 100 and the mounting seat 230 to slide towards the direction close to the base 210 .
[0054] In one embodiment, the base 210 is fixed by a bracket, and the sliding seat 220 and the mounting seat 230 slide relative to each other. Specifically, the end cap 240 is rotatably connected to the sliding seat 220, and the flip end cap 240 is buckled on the sliding seat 220. When the end cap 240 is buckled, the end cap 240 does not contact the blood collection tube 100 at this time, and drives the end cap 240 and the sliding seat 220 to slide toward the base 210. The end cap 240 first contacts the blood collection tube 100, and the sealing cap 242 is inserted into the fixing hole 130 of the blood collection tube 100. In the process of further sliding close to the base 210, the end cap 240 drives the blood collection tube 100 to move toward the base 210, compressing the inner slider 250, and the blood collection tube 100 is further supported on the support 300. Since the collection channel 140 of the blood collection tube 100 has been sealed, the blood to be tested will not overflow during the process of the blood collection tube 100 moving to the support 300. During further sliding, the end cover 240 drives the mounting base 230 to move toward the base 210 to ensure that the end cover 240 is fastened.
[0055] In another embodiment, the mounting seat 230 is fixed by a bracket, and the base 210 and the sliding seat 220 slide relative to each other, so that the blood collection tube 100 is supported on the support member 300 and the end cover 240 is tightly buckled on the shell.
[0056] Optionally, the direct sampling mechanism of peripheral blood further comprises a first detection member 400 and a second detection member 410 respectively arranged on the base 210, the end cap 240 is provided with a locking hook 500, the base 210 is provided with a locking tongue 510, when the sliding seat 220 is in the sampling position, the locking hook 500 is locked and connected to the locking tongue 510 and triggers the first detection member 400. The first detection member 400 is triggered, indicating that the end cap 240 has been tightly buckled and locked. The base 210 is provided with an avoidance hole connected to the sliding cavity, the mounting seat 230 is connected with a triggering member 520, and the triggering member 520 extends out of the avoidance hole setting, when the sliding seat 220 is in the sampling position, the mounting seat 230 slides in a direction away from the end cap 240 and drives the triggering member 520 to trigger the second detection member 410. The avoidance hole is provided at one end of the base 210 away from the end cap 240, and the sample outlet 233 extends out of the base 210 through the avoidance hole, which is convenient for connecting the delivery tube. When the sliding seat 220 moves from the initial position to the injection position, the end of the mounting seat 230 extends out of the avoidance hole, and the second detection member 410 is triggered by the connected trigger member 520. The second detection member 410 is triggered, indicating that there is a blood collection tube 100 in the mounting seat 230. The second detection member 410 can be set on the base 210 or installed on the bracket. In the specific implementation process, the first detection member 400 and the second detection member 410 are trigger switches, and the blood test will be started only when both the first detection member 400 and the second detection member 410 are triggered.
[0057] Furthermore, a second reset member is provided between the mounting seat 230 and the base 210, and the second reset member is provided at one end of the mounting seat 230 away from the end cover 240, and the second reset member is also connected to the base 210. When the sliding seat 220 switches from the injection position to the initial position, the second reset member is used to drive the mounting seat 230 to move toward the end cover 240; a third reset member is provided between the base 210 and the sliding seat 220. When the sliding seat 220 switches from the injection position to the initial position, the third reset member is used to drive the sliding seat 220 to move in a direction away from the base 210.
[0058] In the process of converting the initial position to the injection position, the mounting seat 230 and the sliding seat 220 move toward the base 210. After the injection is completed, the lock of the sliding seat 220 is opened, and the second reset member drives the mounting seat 230 to slide and reset, and the third reset member drives the sliding seat 220 to slide and reset. It can be understood that there is a first spacing space between the mounting seat 230 and the base 210, and the second reset member is located in the first spacing space. Specifically, a fixing groove is provided at one end of the mounting seat 230 located in the sliding cavity of the base 210, one end of the second reset member is located in the fixing groove, and the other end extends out of the fixing groove. When the mounting seat 230 moves, the second reset member is compressed. At the same time, the fixing groove can also play a role of limiting guide to prevent the second reset member from being offset and skewed when being compressed.
[0059] There is a second spacing space between the sliding seat 220 and the base 210. At the same time, the base 210 is provided with a guide seat 211. The sliding seat 220 is connected to the guide column 221, and the guide column 221 is slidably connected to the guide seat 211. The second reset member is sleeved on the guide column 221. When the sliding seat 220 moves toward the base 210, the second reset member is compressed. Of course, the guide column 221 can also prevent the second reset member from deflecting and tilting when being compressed. In addition, the guide seat 211 is provided with a guide chamber, and a sliding bearing is provided in the guide chamber. The guide column 221 is arranged through the guide chamber and is slidably connected to the sliding bearing.
[0060] Optionally, the base 210 is provided with a rotating shaft, and the lock tongue 510 is rotatably connected to the base 210 via the rotating shaft. The lock tongue 510 has a driving end and a reset end, and the driving end and the reset end are respectively located on both sides of the rotating shaft. The base 210 is also provided with a connecting column, and the reset end is connected to a fourth reset member 511, and the fourth reset member 511 is also connected to the connecting column.
[0061] In the specific implementation process, the lock tongue 510 is rotatably connected to the base 210 via the rotating shaft. When the sliding seat 220 slides to make the lock hook 500 move toward the lock tongue 510, under the action of the fourth reset member 511, the lock hook 500 can drive the lock tongue 510 to rotate and reset so that the lock hook 500 and the lock tongue 510 are locked and always in a locked state. Driving the driving end to rotate the lock tongue 510 can release the locking of the lock tongue 510 and the lock hook 500, and then the sliding seat 220 and the mounting seat 230 can slide and reset.
[0062] The utility model also proposes a measurement system, such as Figure 8 As shown, the measuring system includes an analyzing mechanism 10, a mixing pool 12, a diluent tank 20 and an injection mechanism 19, wherein the injection mechanism 19 is the direct peripheral blood injection mechanism as described in the above embodiments. The specific structure of the injection mechanism 19 refers to the above embodiments. Since the measuring system adopts all the technical solutions of all the above embodiments, it has at least all the beneficial effects brought by the technical solutions of the above embodiments, which will not be described one by one here.
[0063] The sample injection mechanism 19 is disposed between the mixing tank 12 and the diluent tank 20, and a second valve 18 is disposed between the sample injection mechanism 19 and the mixing tank 12;
[0064] The diluent tank 20 is used to hold the diluent. The diluent tank 20 is connected to a driving member 24. The driving member 24 is used to add the diluent into the diluent tank 20. The diluent flows into the sample injection mechanism 19 through the diluent tank 20 and is discharged into the mixing tank 12 through the sample outlet 233 of the sample injection mechanism 19. The diluent tank 20 is connected to an electrode 21. The electrode 21 is used to detect the liquid level of the diluent in the diluent tank 20.
[0065] The mixing tank 12 is connected to the analysis mechanism 10, and a first valve 11 is provided between the mixing tank 12 and the analysis mechanism 10. The mixing tank 12 is also connected to a buffer gas tank 13, and the buffer gas tank 13 is connected to a first drive pump 15. A fourth valve 14 is provided between the first drive pump 15 and the buffer gas tank 13. The mixing tank 12 is also connected to a second drive pump 17, and a third valve 16 is provided between the second drive pump 17 and the mixing tank 12.
[0066] In the specific implementation process, the measurement system also includes an external liquid circuit interface, which includes at least a diluent interface 25 and a waste liquid interface 26 to avoid environmental pollution. Of course, according to needs, the external liquid circuit interface also includes interfaces for other reagents.
[0067] In this embodiment, the sample outlet 233 of the sample injection mechanism 19 is connected to the second valve 18 through a liquid delivery pipe, the second valve 18 is connected to the mixing pool 12, one delivery pipe of the mixing pool 12 is connected to the first valve 11, the first valve 11 is connected to the analysis mechanism 10, another delivery pipe of the mixing pool 12 is connected to the buffer gas tank 13, the buffer gas tank 13 is connected to the fourth valve 14, the fourth valve 14 is connected to the first drive pump 15, and the first drive pump 15 is connected to the waste liquid interface 26 of the liquid circuit external interface. The mixing pool 12 is connected to the third valve 16 in a delivery pipe, the third valve 16 is connected to the second drive pump 17, and the second drive pump 17 is connected to the outside air.
[0068] The reagent channel of the injection mechanism 19 is connected to the diluent tank 20, and the diluent tank 20 is provided with an electrode 21 to detect the liquid level to ensure the quantitative delivery of the diluent. Specifically, the diluent delivery amount is set, and the liquid level reaches a predetermined position, and the electrode 21 is disconnected. The diluent tank 20 is connected to the fifth valve 22, and the fifth valve 22 is connected to the sixth valve 23, and the sixth valve 23 is connected to the drive 24, and the drive 24 is a syringe. The sixth valve 23 is connected to the diluent interface 25 of the liquid circuit external interface. The delivery pipeline for the diluent to be delivered from the diluent interface 25 to the diluent tank 20 is also provided with a temperature detector for detecting the temperature of the diluent. The fifth valve 22 is closed, the sixth valve 23 is opened, and the diluent is driven by the drive 24 from the diluent interface 25 through the sixth valve 23 to enter the drive 24, the sixth valve 23 is closed, and the fifth valve 22 is opened, so that the diluent is driven to enter the diluent tank 20 through the fifth valve 22.
[0069] Open the fourth valve 14, start the first drive pump 15, so that the buffer gas tank 13 and the mixing pool 12 form a negative pressure state. Open the second valve 18, because the buffer gas tank 13 and the mixing pool 12 are in a negative pressure state, the diluent in the diluent tank 20 flows into the sampling mechanism 19, and at the same time drives the blood to be tested in the sampling mechanism 19 to flow into the mixing pool 12, and form a mixed liquid in the mixing pool 12. After the electrode 21 is disconnected, close the second valve 18. Open the third valve 16, start the second drive pump 17, so that a positive pressure state is formed in the mixing pool 12; open the first valve 11, because the mixing pool 12 is in a positive pressure state, the mixed liquid of the diluent in the mixing pool 12 and the blood to be tested flows into the analysis mechanism 10, and the blood analysis is completed in the analysis mechanism 10. Thus, after piercing the skin with a blood collection needle, take the handheld disposable blood collection tube 100 to directly collect a certain amount of peripheral blood at the bleeding point, and then directly install the disposable capillary blood collection tube 100 on the Jinyang component for testing. There is no need to use tweezers to clamp the capillary for blood collection and installation, which saves tedious steps and makes the operation simple and convenient.
[0070] The measurement method using this measurement system includes the following measurement steps:
[0071] Hold the blood collection tube 100 to collect blood to be tested, and put the blood collection tube 100 into the sampling assembly 200;
[0072] Start the driving member 24 to add diluent into the diluent tank 20;
[0073] Open the fourth valve 14 and start the first driving pump 15, so that the buffer gas tank 13 and the mixing tank 12 form a negative pressure state;
[0074] The second valve 18 is opened. Since the buffer gas tank 13 and the mixing pool 12 are in a negative pressure state, the diluent in the diluent tank 20 flows into the sample injection mechanism 19, and the blood to be tested in the sample injection mechanism 19 is driven to flow into the mixing pool 12, and a mixed liquid is formed in the mixing pool 12;
[0075] After the electrode 21 is disconnected, the second valve 18 is closed;
[0076] Open the third valve 16 and start the second driving pump 17 to form a positive pressure state in the mixing tank 12;
[0077] The first valve 11 is opened, and since the mixing pool 12 is in a positive pressure state, the mixed liquid of the diluent and the blood to be tested in the mixing pool 12 flows into the analysis mechanism 10, and the blood analysis is completed in the analysis mechanism 10.
[0078] It is understandable that before the handheld blood collection tube 100 collects the blood to be tested, it is necessary to pierce the skin and collect blood at the bleeding site. The blood collection tube 100 is placed in the accommodating chamber 231 of the sampling assembly 200, the end cap 240 is turned over and snapped, and the sliding seat 220 is driven to slide in the direction of the base 210, and the first detection member 400 and the second detection member 410 are both triggered to carry out the next measurement process. The diluent is accommodated by the action of the driving member 24, and the diluent is further transported to the diluent tank 20. The fourth valve 14 is opened, and the first driving pump 15 is started, so that the buffer gas tank 13 and the mixing pool 12 form a negative pressure state; the second valve 18 is opened, and since the buffer gas tank 13 and the mixing pool 12 are in a negative pressure state, the diluent in the diluent tank 20 flows into the sampling mechanism 19, and the blood to be tested and the diluent are driven to be discharged to the mixing pool 12 through the sample outlet 233. Open the third valve 16 and start the second driving pump 17 to form a positive pressure state in the mixing pool 12; open the first valve 11, and since the mixing pool 12 is in a positive pressure state, the mixed liquid of the diluent and the blood to be tested in the mixing pool 12 flows into the analysis mechanism 10, and the analysis mechanism 10 completes the subsequent diff blood separation, rbc blood separation and counting process. The quantitative collection and transmission of blood samples can ensure the accuracy and stability of blood samples, providing a basic guarantee for blood analysis measurement.
[0079] After completing the blood analysis, the delivery pipeline and the sampling assembly 200 can also be cleaned. Specifically, the second valve 18 is opened. Since the buffer gas tank 13 and the mixing pool 12 are in a negative pressure state, the diluent in the diluent tank 20 flows into the sampling mechanism 19, and the blood collection tube 100 is rinsed, so that the diluent enters the mixing tank. Close the second valve 18, open the third valve 16, start the second drive pump 17, so that a positive pressure state is formed in the mixing pool 12, and open the first valve 11. Since the mixing pool 12 is in a positive pressure state, the mixed liquid of the diluent in the mixing pool 12 and the blood to be tested flows into the analysis mechanism 10. By cleaning and emptying, it is ensured that there is no diluent in the direct sampling assembly 200 of peripheral blood, which is convenient for users to take out the disposable capillary blood collection tube 100. After cleaning the corresponding liquid path part, the pipeline is emptied. The purpose of emptying is to prevent the user from following the capillary when taking out the disposable capillary blood collection tube 100, thereby improving the safety of the instrument.
[0080] The above description is only an optional embodiment of the present invention, and does not limit the patent scope of the present invention. All equivalent structural changes made by using the contents of the present invention specification and drawings under the inventive concept of the present invention, or directly / indirectly applied in other related technical fields are included in the patent protection scope of the present invention.
Claims
1. A peripheral blood direct sampling mechanism, characterized in that: include: A blood collection tube, the blood collection tube comprising a tube body and a hand-held part, the tube body having a collection channel for collecting blood to be tested, the hand-held part being arranged near one end of the tube body and protruding from the outer periphery of the tube body; and An injection assembly, wherein the injection assembly is provided with a sample outlet and a reagent channel for conveying a diluent, the reagent channel includes a first conveying channel, the injection assembly includes a shell, a mounting seat and an end cover, wherein the shell is provided with a sliding cavity, the mounting seat is slidably arranged in the sliding cavity, the mounting seat is provided with a receiving cavity for placing the blood collection tube and a mixing cavity connected to the receiving cavity, the mixing cavity is also connected to the sample outlet, the end cover is used to be snap-fitted and connected to the shell, the sample outlet is provided at one end of the mounting seat away from the end cover, the first conveying channel is provided at the end cover, when the end cover is snap-fitted to the shell and moves toward the sample outlet, the first conveying channel is connected to the collection channel, the diluent flows into the collection channel from the first conveying channel, and drives the blood to be tested to flow into the mixing cavity and be discharged through the sample outlet.
2. The peripheral blood direct sampling mechanism according to claim 1, characterized in that: The tube body includes a supporting portion and a connecting portion, the hand-held portion is arranged on the outer periphery of the connecting portion, the supporting portion is conically arranged, the inner wall contour of the accommodating cavity is matched with the outer wall contour of the blood collection tube, the inner wall of the accommodating cavity is provided with a supporting member, the supporting member is used for sealing contact and connecting the supporting portion, and forming a conveying gap between the outer peripheral surface of the supporting portion and the inner wall of the accommodating cavity, the conveying gap is connected with the mixing cavity, the reagent channel also includes a second conveying channel, the second conveying channel is opened on the mounting seat, and the second conveying channel is connected with the conveying gap, the second conveying channel conveys the diluent into the conveying gap and further into the mixing cavity.
3. The peripheral blood direct sampling mechanism according to claim 2, characterized in that: A fixing hole connected to the collection channel is defined at one end of the connecting portion away from the supporting portion, and the end cover is provided with a sealing cap, and the sealing cap defines a first outlet, and the first outlet is connected to the first delivery channel. When the end cover is buckled onto the shell and moves toward the sample outlet, the sealing cap is sealingly inserted into the fixing hole, and the first outlet is connected to the fixing hole in a coordinated manner.
4. The peripheral blood direct sampling mechanism according to claim 1, characterized in that: The peripheral blood direct sampling mechanism also includes an inner slider, the mounting seat is provided with a first groove, the inner slider is slidably arranged in the first groove, and a first reset member is also provided between the inner slider and the first groove, the first reset member is used to drive the blood collection tube to move in a direction away from the mounting seat, and when the blood collection tube is placed in the accommodating cavity, the hand-held part is supported on the inner slider.
5. The peripheral blood direct sampling mechanism according to any one of claims 1 to 4, characterized in that: The housing comprises a base and a sliding base, the end cover is used to buckle and connect the sliding base, the sliding base has an initial position away from the base and an injection position close to the base, and the sliding base slides toward the base so that the sliding base switches from the initial position to the injection position; The end cover is buckled and connected to the sliding seat, and when the sliding seat switches from the initial position to the injection position, the end cover drives the blood collection tube and the mounting seat to slide towards the direction close to the base.
6. The peripheral blood direct sampling mechanism according to claim 5, characterized in that: The direct peripheral blood sampling mechanism also includes a first detection member and a second detection member respectively arranged on the base, the end cover is provided with a locking hook, and the base is provided with a locking tongue. When the sliding seat is in the injection position, the locking hook is locked and connected to the locking tongue and triggers the first detection member; the base is provided with an avoidance hole connected to the sliding cavity, and the mounting seat is connected with a trigger member, and the trigger member extends out of the avoidance hole. When the sliding seat is in the injection position, the mounting seat slides in a direction away from the end cover and drives the trigger member to trigger the second detection member.
7. The peripheral blood direct sampling mechanism according to claim 6, characterized in that: A second reset member is provided between the mounting seat and the base, the second reset member is provided at one end of the mounting seat away from the end cover, and the second reset member is also connected to the base, and when the sliding seat is switched from the injection position to the initial position, the second reset member is used to drive the mounting seat to move toward the end cover; a third reset member is provided between the base and the sliding seat, and when the sliding seat is switched from the injection position to the initial position, the third reset member is used to drive the sliding seat to move in a direction away from the base.
8. The peripheral blood direct sampling mechanism according to claim 6, characterized in that: The base is provided with a rotating shaft, and the lock tongue is rotatably connected to the base via the rotating shaft. The lock tongue has a driving end and a reset end, and the driving end and the reset end are respectively located on both sides of the rotating shaft. The base is also provided with a connecting column, and the reset end is connected to a fourth reset member, and the fourth reset member is also connected to the connecting column.
9. The peripheral blood direct sampling mechanism according to claim 6, characterized in that: The base is provided with a guide seat, the sliding seat is connected to a guide column, and the guide column is slidably connected to the guide seat.
10. A measurement system, characterized in that: It comprises an analysis mechanism, a mixing tank, a diluent tank and a sampling mechanism, wherein the sampling mechanism is a peripheral blood direct sampling mechanism as claimed in any one of claims 1 to 9; The sample injection mechanism is arranged between the mixing tank and the diluent tank, and a second valve is arranged between the sample injection mechanism and the mixing tank; The diluent tank is used to hold a diluent, and the diluent tank is connected to a driving member, and the driving member is used to add a diluent into the diluent tank, and the diluent flows into the injection mechanism through the diluent tank, and is discharged into the mixing tank through the sample outlet of the injection mechanism, and the diluent tank is connected to an electrode, and the electrode is used to detect the liquid level of the diluent in the diluent tank; The mixing pool is connected to the analysis mechanism, and a first valve is provided between the mixing pool and the analysis mechanism. The mixing pool is also connected to a buffer gas tank, and the buffer gas tank is connected to a first drive pump. A fourth valve is provided between the first drive pump and the buffer gas tank. The mixing pool is also connected to a second drive pump, and a third valve is provided between the second drive pump and the mixing pool.