Aliphatic element preparation assembly

Abstract

The utility model discloses an aliphatic element preparation assembly which comprises a centrifugal mechanism, a connecting pipeline, a reagent chamber, a counterweight chamber, an incubation chamber, a collecting pipe and a waste liquid bag, the connecting pipeline comprises a first pipeline, a second pipeline, a third pipeline and a fourth pipeline which are respectively connected with the centrifugal mechanism; the reagent chamber is connected to the first pipeline, the waste liquid bag is connected to the first pipeline through a first branch, and the incubation chamber is connected to the first pipeline through a second branch; the collecting pipe is connected to the second pipeline, the counterweight chamber is connected to the third pipeline, one end of the fourth pipeline is connected to the centrifugal tube, and the other end of the fourth pipeline is connected to the first branch; when the device is used, fat can be cleaned, digested and centrifuged in cooperation with a pinch valve, a peristaltic pump and a power device, the fat does not need to be manually converted in different devices in a sterile pipeline, and the automation degree is high.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, in particular to a fat element preparation component. Background Art

[0002] Adipocytes are surrounded by adipose matrix, namely SVF (Stromal Vascular Fraction), which represents a group of heterogeneous cells, also known as adipocytes. SVF can be obtained by processing fat cells in the abdomen, buttocks, breasts and internal organs of humans. The method is as follows: obtain adipose tissue after liposuction, wash to remove blood cells, digest with collagenase to obtain a single cell suspension, filter through a 0.22um filter to remove undigested tissue residues, and the precipitate obtained after centrifugation due to its light specific gravity is SVF.

[0003] At present, the processing and separation of fat in the human body are carried out using different devices. The fat needs to be manually transferred between different devices, and the degree of automation is low, which cannot meet clinical needs. Utility Model Content

[0004] In view of the defects in the prior art, the purpose of the utility model is to provide a fat element preparation component integrating fat processing and separation pipelines.

[0005] The technical solution adopted by the utility model is:

[0006] A fat element preparation component comprises a centrifuge, a connecting pipeline, a reagent chamber, a weight chamber, an incubation chamber, a collecting tube and a waste liquid bag; the connecting pipeline comprises a first pipeline, a second pipeline, a third pipeline and a fourth pipeline respectively connected to the centrifuge; the reagent chamber is connected to the first pipeline, the waste liquid bag is connected to the first pipeline through a first branch, and the incubation chamber is connected to the first pipeline through a second branch; the collecting tube is connected to the second pipeline, the weight chamber is connected to the third pipeline, and one end of the fourth pipeline is connected to the centrifuge tube, and the other end is connected to the first branch.

[0007] Furthermore, the centrifugal mechanism includes a centrifuge tube and a counterweight tube, the centrifuge tube and the counterweight tube are arranged at intervals, the first pipeline, the second pipeline and the fourth pipeline are respectively connected to the centrifuge tube, and the third pipeline is connected to the counterweight tube.

[0008] Furthermore, the reagent chamber includes an enzyme bag, a protective liquid bag and a physiological saline bag, and the enzyme bag, the protective liquid bag and the physiological saline bag are connected to the first pipeline through the corresponding third branch, fourth branch and fifth branch respectively.

[0009] Further, the centrifugal mechanism also includes an anti-winding device, which includes a fixed part, a rotating part, a first liquid pipe, a second liquid pipe, a third liquid pipe and a fourth liquid pipe, the fixed part is rotatably installed on the outer periphery of the rotating part, and a first annular cavity, a second annular cavity, a third annular cavity and a fourth annular cavity are provided between the fixed part and the rotating part and spaced apart in the vertical direction; the first pipeline, the second pipeline, the third pipeline and the fourth pipeline are all fixed to the side wall of the fixed part, and are respectively connected to the first annular cavity, the second annular cavity, the third annular cavity and the fourth annular cavity; the first ends of the first liquid pipe, the second liquid pipe, the third liquid pipe and the fourth liquid pipe are all vertically connected to the rotating part, and are respectively connected to the first annular cavity, the second annular cavity, the third annular cavity and the fourth annular cavity, the second ends of the first liquid pipe, the second liquid pipe and the fourth liquid pipe are connected to the centrifuge tube, and the second end of the third liquid pipe is connected to the counterweight pipe.

[0010] Furthermore, the height of the second end of the fourth liquid tube is 2 ml higher than the height of the second end of the first liquid tube.

[0011] Furthermore, a 100um filter membrane is installed between the collecting tube and the centrifugal mechanism, and a hydrophobic breathable membrane is installed between the collecting tube and the end of the second pipeline.

[0012] Further, the counterweight chamber is connected to the end of the third pipeline.

[0013] Additional aspects and advantages of the present application will be given in part in the description below, and in part will become apparent from the description below, or will be learned through the practice of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the specific implementation of the utility model or the technical solution in the prior art, the following is a brief introduction to the drawings required for the specific implementation or the prior art description. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, each element or part is not necessarily drawn according to the actual scale.

[0015] Figure 1 A schematic diagram of the structure of the fat element preparation assembly provided in the embodiment of the present application;

[0016] Figure 2 A schematic diagram of the structure of the first centrifuge tube assembly provided in an embodiment of the present application;

[0017] Figure 3 A schematic diagram of the structure of the second centrifuge tube assembly provided in an embodiment of the present application;

[0018] Figure 4This is a schematic diagram of the structure of the fat nucleus preparation component in use according to an embodiment of the present application.

[0019] Among them, the counterweight chamber 1, the collecting tube 2, the filter membrane 3, the hydrophobic breathable membrane 4, the first pipeline 5, the second pipeline 6, the third pipeline 7, the fourth pipeline 8, the first branch 9, the second branch 10, the third branch 11, the fourth branch 12, the fifth branch 13, the enzyme bag 14, the protective liquid bag 15, the physiological saline bag 16, the waste liquid bag 17, the incubation chamber 18, the anti-winding device 19, the rotating part 191, the fixed part 192, the first annular cavity 193, the second annular cavity 194, the third annular cavity 195, the fourth annular cavity 156, the centrifuge tube 20, and the counterweight tube 21. DETAILED DESCRIPTION

[0020] Here, it should be noted that the functions and methods involved in the present invention are merely conventional adaptive applications of the prior art. Therefore, the improvement of the present invention on the prior art is essentially the connection relationship between the hardware, rather than the functions and methods themselves. That is, although the present invention involves some functions and methods, it does not include improvements to the functions and methods themselves. The description of the functions and methods in the present invention is to better illustrate the present invention so as to better understand the present invention.

[0021] The following embodiments of the technical solution of the utility model are described in detail in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the utility model, and are therefore only used as examples, and cannot be used to limit the protection scope of the utility model.

[0022] It should be noted that, unless otherwise specified, the technical terms or scientific terms used in this application should have the common meanings understood by technicians in the field to which the utility model belongs.

[0023] See also Figure 1 to Figure 4 The present application discloses a fat element preparation component, comprising a centrifugal mechanism, a connecting pipeline, a reagent chamber, a weight chamber 1, an incubation chamber 18, a collecting tube 2 and a waste liquid bag 17; the connecting pipeline comprises a first pipeline 5, a second pipeline 6, a third pipeline 7 and a fourth pipeline 8 respectively connected to the centrifugal mechanism; the reagent chamber is connected to the first pipeline 5, the waste liquid bag 17 is connected to the first pipeline 5 through a first branch 9, and the incubation chamber 18 is connected to the first pipeline 5 through a second branch 10; the collecting tube 2 is connected to the second pipeline 6, the weight chamber 1 is connected to the third pipeline 7, one end of the fourth pipeline 8 is connected to the centrifuge tube, and the other end is connected to the first branch 9.

[0024] The present application provides a centrifugal mechanism and a reagent chamber, a weight chamber 1, an incubation chamber 18, a collection tube 2 and a waste liquid bag 17 connected to the centrifugal mechanism through connecting pipelines. When used, in conjunction with a clamping valve, a peristaltic pump and a power device, fat can be cleaned, digested and centrifuged. In the sterile pipeline, fat does not need to be manually converted between different devices, and the degree of automation is high.

[0025] The incubation chamber 18 includes an incubation bag and a shaking table connected to the incubation bag, and the fat is digested by the incubation bag.

[0026] The centrifugal mechanism includes a centrifuge tube and a counterweight tube 21 , which are arranged at intervals, the first pipeline 5 , the second pipeline 6 and the fourth pipeline 8 are respectively connected to the centrifuge tube, and the third pipeline 7 is connected to the counterweight tube 21 .

[0027] The weight tube 21 can contain weight liquid, which can be physiological saline, for weight balancing. The weight tube 21 is connected to the end of the third pipeline 7 .

[0028] The top of the centrifuge tube is provided with an injection port for injecting fat, and also with an extraction port, which can be used to manually suck out the fat elements using a syringe.

[0029] In order to prevent the pipeline from being entangled, the centrifugal mechanism also includes an anti-entanglement device 19, which includes a fixed part 192, a rotating part 191, a first liquid pipe, a second liquid pipe, a third liquid pipe and a fourth liquid pipe. The fixed part 192 is rotatably installed on the outer periphery of the rotating part 191, and a first annular cavity 193, a second annular cavity 194, a third annular cavity 195 and a fourth annular cavity are arranged between the fixed part 192 and the rotating part 191 and at intervals in the vertical direction; in this embodiment, the outer wall of the middle part of the rotating part 191 is slightly concave inward to form a circumferentially arranged groove, and the groove cooperates with the inner wall of the outer fixed part 192 to form a cavity, and sealing rings are arranged at the upper and lower ends and the middle interval of the cavity to separate the cavity into a first annular cavity arranged vertically and a second annular cavity 194. The first pipeline 5, the second pipeline 6, the third pipeline 7 and the fourth pipeline 8 are all fixed on the side wall of the fixed part 192, and are respectively connected with the first annular cavity 193, the second annular cavity 194, the third annular cavity 195 and the fourth annular cavity; the first ends of the first liquid pipe, the second liquid pipe, the third liquid pipe and the fourth liquid pipe are all vertically connected to the rotating part 191, and are respectively connected with the first annular cavity 193, the second annular cavity 194, the third annular cavity 195 and the fourth annular cavity, the second ends of the first liquid pipe, the second liquid pipe and the fourth liquid pipe are connected with the centrifuge tube, and the second end of the third liquid pipe is connected with the counterweight pipe 21.

[0030] To facilitate the discharge of different substances, the second end of the first liquid tube is close to the bottom of the centrifuge tube, the height of the second end of the fourth liquid tube is 2 ml higher than the height of the second end of the first liquid tube, and the height of the second end of the first liquid tube is higher than the height of the second end of the second liquid tube.

[0031] The reagent chamber includes an enzyme bag 14, a protective liquid bag 15 and a physiological saline bag 16, and the enzyme bag 14, the protective liquid bag 15 and the physiological saline bag 16 are connected to the first pipeline 5 through the corresponding third branch 11, the fourth branch 12 and the fifth branch 13 respectively.

[0032] The collecting tube 2 is used to collect the processed fat elements. A 100um filter membrane 3 is installed between the collecting tube 2 and the centrifugal mechanism, and a hydrophobic breathable membrane 4 is installed between the collecting tube 2 and the end of the second pipeline 6. When in use, it cooperates with the peristaltic pump to pump the processed fat elements into the collecting tube 2.

[0033] When in use, the components of the present application can be installed on a cabinet, the centrifugal mechanism is installed in the cabinet, the connecting pipelines, the reagent chamber, the counterweight chamber 1, the waste liquid bag 17, the peristaltic pump, the clamp valve and the incubation chamber 18 are all installed outside the cabinet, the counterweight tube 21 of the centrifugal mechanism and the centrifugal tube are respectively installed at both ends of the mounting bracket, the output shaft of the power device is connected to the middle of the mounting bracket to drive the counterweight tube 21 of the centrifugal mechanism and the centrifugal tube to rotate, and the rotating part 191 of the anti-winding device 19 is fixed to the middle of the mounting bracket; the first branch 9, the second branch 9 The second branch 10, the third branch 11, the fourth branch 12 and the fifth branch 13 are respectively provided with pinch valves, the second branch 10 is provided with a peristaltic pump between the incubation chamber 18 and the corresponding pinch valve, the first pipeline 5 is provided with a peristaltic pump between the reagent chamber and the centrifugal mechanism, the second pipeline 6 is provided with a peristaltic pump, the third pipeline 7 is provided with a peristaltic pump between the weight chamber 1 and the centrifugal mechanism, and the end of the fourth pipeline 8 is provided with a peristaltic pump; the following functions can be realized through the pinch valves, the peristaltic pump and the power device:

[0034] 1. Blood-containing fat can be manually injected into the centrifuge tube through the inlet and outlet.

[0035] 2. By operating the peristaltic pump on the first pipeline 5 and cooperating with the pinch valves on the fourth branch 12 and / or the fifth branch 13, the protective liquid and / or physiological saline can be pumped into the centrifuge tube through the first pipeline 5 respectively; or by cooperating with the pinch valve on the first branch 9, the waste liquid in the centrifuge tube can be pumped into the waste liquid bag 17 through the first pipeline 5.

[0036] 3. The fat in the centrifuge tube can be pumped into the incubation chamber 18 by operating the peristaltic pump on the first pipeline 5 and the second branch 10 in cooperation with the pinch valve on the second branch 10; the enzyme in the enzyme bag 14 can be pumped into the incubation chamber 18 in cooperation with the peristaltic pump on the second branch 10 and the pinch valves on the second branch 10 and the third branch 11.

[0037] 4. The peristaltic pump on the fourth pipeline 8 rotates alternately forward and reversely, and cooperates with the pinch valve on the first branch 9 to drive the fat in the centrifuge tube to be "pumped-discharged" back and forth between the centrifuge tube and the third pipeline 7, so that the fat and the liquid added to the fat are evenly mixed.

[0038] 5. The processed fat cells can be pumped into the collection tube 2 by the peristaltic pump on the second pipeline 6 .

[0039] 6. The peristaltic pump on the third pipeline 7 can be operated to pump the weight liquid into the weight tube 21.

[0040] In this application, unless otherwise clearly specified and limited, the terms "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be an electrical connection; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in this utility model can be understood according to specific circumstances.

[0041] In the specification of the present utility model, a lot of specific details are described. However, it is understood that the embodiments of the present utility model can be practiced without these specific details. In some examples, well-known methods, systems and techniques are not shown in detail so as not to obscure the understanding of this specification.

[0042] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, systems, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, systems, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, unless they are contradictory.

[0043] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents. These modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the utility model, and they should all be included in the scope of the claims and specification of the utility model.

Claims

1. A fat element preparation component, characterized in that: It includes a centrifugal mechanism, connecting pipelines, a reagent chamber, a counterweight chamber, an incubation chamber, a collecting tube and a waste liquid bag; the connecting pipelines include a first pipeline, a second pipeline, a third pipeline and a fourth pipeline respectively connected to the centrifugal mechanism; the reagent chamber is connected to the first pipeline, the waste liquid bag is connected to the first pipeline through a first branch, and the incubation chamber is connected to the first pipeline through a second branch; the collecting tube is connected to the second pipeline, the counterweight chamber is connected to the third pipeline, one end of the fourth pipeline is connected to the centrifugal tube of the centrifugal mechanism, and the other end is connected to the first branch.

2. The fat element preparation assembly according to claim 1, characterized in that: The centrifugal mechanism comprises a centrifuge tube and a counterweight tube, the centrifuge tube and the counterweight tube are arranged at intervals, the first pipeline, the second pipeline and the fourth pipeline are respectively connected to the centrifuge tube, and the third pipeline is connected to the counterweight tube.

3. The fat element preparation assembly according to claim 2, characterized in that: The reagent chamber comprises an enzyme bag, a protective liquid bag and a physiological saline bag, and the enzyme bag, the protective liquid bag and the physiological saline bag are connected to the first pipeline through the corresponding third branch, fourth branch and fifth branch respectively.

4. The fat element preparation assembly according to claim 3, characterized in that: The centrifugal mechanism also includes an anti-winding device, which includes a fixed part, a rotating part, a first liquid pipe, a second liquid pipe, a third liquid pipe and a fourth liquid pipe, the fixed part is rotatably installed on the outer periphery of the rotating part, and a first annular cavity, a second annular cavity, a third annular cavity and a fourth annular cavity are provided between the fixed part and the rotating part and spaced apart in the vertical direction; the first pipeline, the second pipeline, the third pipeline and the fourth pipeline are all fixed to the side wall of the fixed part, and are respectively connected to the first annular cavity, the second annular cavity, the third annular cavity and the fourth annular cavity; the first ends of the first liquid pipe, the second liquid pipe, the third liquid pipe and the fourth liquid pipe are all vertically connected to the rotating part, and are respectively connected to the first annular cavity, the second annular cavity, the third annular cavity and the fourth annular cavity, the second ends of the first liquid pipe, the second liquid pipe and the fourth liquid pipe are connected to the centrifuge tube, and the second end of the third liquid pipe is connected to the counterweight pipe.

5. The fat element preparation assembly according to claim 4, characterized in that: The height of the second end of the fourth liquid tube is 2 ml higher than the height of the second end of the first liquid tube.

6. The fat element preparation assembly according to claim 1, characterized in that: A 100um filter membrane is installed between the collecting tube and the centrifugal mechanism, and a hydrophobic breathable membrane is installed between the collecting tube and the end of the second pipeline.

7. The fat element preparation assembly according to claim 1, characterized in that: The counterweight chamber is connected to the end of the third pipeline.

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