Automatic micro-droplet instrument for laboratory

Abstract

The utility model discloses an automatic micro-droplet instrument for a laboratory, which belongs to the related technical field of laboratory instruments and equipment and comprises a cabinet, the inside of the cabinet is divided into an upper layer and a lower layer by a support plate, and an electric mounting plate is detachably connected above the support plate. A lifting baffle mechanism, a micro-droplet mechanism, a visual detection module, an automatic screen turning mechanism and a control module are arranged on the upper layer of the cabinet, an XY axial movement mechanism is installed on the lower layer of the cabinet, and an observation window and a jig disc ejection opening are formed in the front portion of the cabinet. Structures and functional characteristics of all mechanisms or modules are fully utilized, in the using process, the automatic clamp mechanism pops up automatically, only a jig disc needs to be manually placed at a designated position of a clamp, an instrument automatically completes liquid adding and detection of the jig disc, and the automatic clamp mechanism pops up again after liquid adding and detection are completed. The device has the advantages of high automation degree, simplicity in operation, accuracy in liquid adding, high production efficiency, low manual operation intensity and the like.

Description

Technical Field

[0001] The utility model belongs to the field of laboratory instruments and equipment, and specifically relates to an automatic micro-droplet instrument for a laboratory. Background Art

[0002] At present, the laboratory often uses traditional manual operation to prepare low-dose reagents. The routine steps are as follows: first, the experimenter uses a micropipette to absorb a certain amount of test solution. This step is crucial and directly determines the concentration and dosage of the reagent; then, the test solution is transferred to the fixture plate in turn. Generally speaking, the fixture plate is densely arranged with grooves, and each groove needs to titrate the same dose of test solution. Therefore, the operation needs to be very cautious in this process to avoid splashing or loss of the test solution; finally, after completing the titration of the entire plate of test solution, the experimenter puts the fixture plate under a microscope to observe and determine whether there is liquid in each groove. If there is no liquid, the titration is repeated. This operation method is not only inefficient and labor-intensive, but also often causes operational errors due to continuous repetitive labor, resulting in preparation errors; in addition, the use of a microscope for detection is prone to inaccurate detection due to deviations in placement. Utility Model Content

[0003] In view of this, the utility model provides a laboratory automatic micro-droplet instrument, which combines a precision injection pump with a high-pixel CMOS Gigabit Ethernet industrial area array camera and configures a servo-driven XY-axis linear motor module to achieve automatic titration, precise control and visual inspection of laboratory liquids, thereby replacing tedious manual operations and completing the automatic preparation of trace liquid reagents. The instrument has the characteristics of high precision, high automation and high efficiency, and can be widely used in chemical analysis, biomedicine, drug research and development and other fields.

[0004] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0005] A laboratory automatic micro-droplet instrument comprises: a cabinet, wherein the interior of the cabinet is divided into an upper and lower layer by a support plate, an electrical installation plate is detachably connected above the support plate, a lifting baffle mechanism, a micro-droplet mechanism, a visual detection module, an automatic screen flipping mechanism, and a control module are arranged on the upper layer, an XY axial movement mechanism is installed on the lower layer, and an observation window and a fixture plate ejection outlet are arranged at the front of the cabinet.

[0006] The X-axis linear motor module and the Y-axis linear motor module in the XY axial moving mechanism are cross-distributed; the bottom of the X-axis linear motor module is connected to the cabinet, and the upper part is slidably connected to the X-axis slider; the Y-axis linear motor module is installed on the X-axis slider, and the upper part is slidably connected to the Y-axis slider; an automatic clamping mechanism is installed on the Y-axis slider for fixing the fixture disk.

[0007] The automatic clamping mechanism includes a clamping positioning device and an automatic pop-up device; the clamping positioning device is provided with grooves on the left and right sides of the clamp body, and springs are placed in the grooves. The clamp baffle is slidably connected to the clamp body through the springs. An LED light board is installed on the upper part of the clamp body, and an LED lamp cover is provided on the upper part of the LED light board. A heat sink is bonded to the lower part which is symmetrical on the left and right sides, and a fixture plate is placed on the LED lamp cover; micro slide rails are symmetrically installed on the left and right sides of the supporting shell in the automatic pop-up device, and a first planetary reduction stepper motor is installed inside. A micro gear is installed on the output shaft of the first planetary reduction stepper motor, and a rack is installed at the bottom of the clamp body. The micro gear is meshed with the rack, and a first proximity sensor is installed at an appropriate position at the rear of the supporting shell.

[0008] The clamping and positioning device is slidably connected to the automatic pop-up device via the micro slide rail.

[0009] The first connecting plate in the lifting baffle mechanism is rigidly connected to the cabinet, a micro electric push rod is installed at the first connecting plate, the end of the micro electric push rod is connected to the movable baffle, a second proximity sensor is set at the initial position, and a hollow shell is installed at the ejection outlet of the fixture disk, a guide groove is set inside the hollow shell, and the movable baffle is slidably connected to the hollow shell through the guide groove.

[0010] The micro-droplet mechanism includes two parts: injection and addition. In the injection part, a precision injection pump quantitatively injects the test solution from the stock solution reagent bottle into the addition needle through a capillary channel. The addition part adopts a through-type stepper motor, the end of which is connected to a specific liquid addition fixture and a liquid addition needle, and a third proximity sensor is arranged at the tail end, which is connected to the electrical installation board through a second connecting board. The precision injection pump, the stock solution reagent bottle, and the through-type stepper motor are all arranged on the electrical installation board.

[0011] The visual inspection module includes: an industrial area array camera, a variable-magnification telecentric lens, and a connector; the industrial area array camera is connected to a cabinet through the connector, and the variable-magnification telecentric lens is installed at the end.

[0012] The fixed shell in the automatic screen flipping mechanism is connected to the cabinet through screws, miniature bearings are installed on the left and right sides, and a second planetary reduction stepper motor is installed on the bottom. The output shaft of the second planetary reduction stepper motor is connected to the driving wheel, and the power and rotation speed are transmitted to the driven wheel through a belt; the driven wheel is installed on the protruding cylinder on the left side of the screen fixing plate, and a circular groove is opened on the right side of the screen fixing plate for installing the pin shaft. The protruding cylinder on the left side of the screen fixing plate and the pin shaft installed on the right side are respectively interference fit with the miniature bearings on both sides of the screen fixing plate through top screws; the screen cover plate fixes the LED display screen on the screen fixing plate by a buckle and slot connection method; a row of membrane switches is arranged on the front of the fixed shell.

[0013] The control module uses a PLC / LED display screen to achieve automatic control and visual interaction.

[0014] Beneficial effects of the utility model:

[0015] The utility model makes full use of the structural and functional characteristics of each mechanism or module. During use, the automatic clamp mechanism pops up automatically. It only needs to manually place the fixture tray at the specified position of the fixture. The instrument automatically completes the liquid addition and detection of the fixture tray. After completion, the automatic clamp mechanism pops up again. It has the advantages of high degree of automation, simple operation, accurate liquid addition, high production efficiency, and low manual labor intensity.

[0016] Preferably, the XY axial moving mechanism adopts a linear motor module, which generates linear motion through the action of electromagnetic force, and has the advantages of high positioning accuracy, fast response speed, high power density, compact structure, etc.

[0017] Preferably, in order to improve the convenience and practicality of the clamping operation, the automatic clamping mechanism includes an automatic pop-up device, which can automatically pop out the clamping positioning device from the shell to avoid operation inside the cabinet, and is specifically implemented using a "stepping motor + gear / bar" transmission method.

[0018] Preferably, the continuous liquid addition process is completed using a precision injection pump in conjunction with a through-type stepping motor. The minimum drop volume of the precision injection pump is 5 microliters, and the repeatability accuracy is less than 0.05%.

[0019] Preferably, the industrial area array camera in the visual inspection module adopts Hikvision MV-CS200-10GM / C series products, which are equipped with Sony's IMX183 CMOS chip, have the advantages of low noise, high resolution, excellent image, high cost performance, etc., and can transmit images through the Gigabit Ethernet interface, can quickly transmit data in real time, and the frame rate at full resolution can reach 5.9fps; it is also equipped with Hikvision GM1084 / 756 zoom telecentric lens.

[0020] As a preference, in order to improve the practicality and high-end positioning of the instrument, provide the operator with a better operating experience, and make it easier and more intuitive to observe the identification photos of the liquid in the fixture plate, an automatic screen flipping function is added, and the automatic screen flipping mechanism adopts a "stepping motor + belt" transmission method to realize the flipping action.

[0021] Preferably, the flow-through materials such as the precision injection pump body, capillary, connector, and liquid-adding needle are all made of polytetrafluoroethylene (PTFE) to improve the corrosion resistance of the instrument.

[0022] Preferably, the rotation speed, stroke and acceleration of the linear motor module, planetary reduction stepper motor and through-type stepper motor are adjustable and controllable, and the instrument is electrically driven and can be used as long as it is powered on, avoiding the use of an air source, so there is no restriction on the use environment.

[0023] Preferably, the visual detection module and the micro-droplet mechanism are arranged symmetrically inside the cabinet to rationally utilize the internal space of the instrument.

[0024] Preferably, a high-power LED light board is installed in the automatic clamping mechanism to provide the lighting requirements of the visual inspection module, and the heat sink is used to dissipate wind and heat for the LED light board. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a schematic diagram of the internal structure of the utility model.

[0026] Figure 2 It is a schematic diagram of the external structure of the utility model.

[0027] Figure 3 Schematic diagram of the XY axial movement mechanism.

[0028] Figure 4 This is the exploded diagram of the automatic clamping mechanism.

[0029] Figure 5 Schematic diagram of the lifting baffle mechanism.

[0030] Figure 6 Schematic diagram of the micro-droplet mechanism.

[0031] Figure 7 Schematic diagram of the visual inspection module.

[0032] Figure 8 This is an exploded view of the automatic screen flipping mechanism.

[0033] In the figure:

[0034] 1. Cabinet; 11. Cabinet body; 12. Support plate; 13. Electrical installation plate; 14. Observation window; 15. Jig tray ejection outlet; 16. Adjustable support seat;

[0035] 2. XY axial moving mechanism; 21. X-axis linear motor module; 211. X-axis slider; 212. X-axis positive limit switch; 213. X-axis origin switch; 214. X-axis negative limit switch; 22. Y-axis linear motor module; 221. Y-axis slider;

[0036] 3. Automatic clamping mechanism; 31. Clamping and positioning device; 311. Clamp body; 312. Spring; 313. Clamp baffle; 314. LED lamp board; 315. LED lamp cover; 316. Heat sink; 32. Automatic pop-up device; 321. Support shell; 322. Micro slide rail; 323. First planetary reduction stepping motor; 324. Micro gear; 325. Rack; 326. First proximity sensor;

[0037] 4. Lifting baffle mechanism; 41. Micro electric push rod; 42. First connecting plate; 43. Movable baffle; 44. Hollow shell; 45. Second proximity sensor; 46. Connector;

[0038] 5. Micro-droplet mechanism; 51. Precision injection pump; 52. Capillary channel; 53. Stock solution reagent bottle; 54. Liquid adding needle; 55. Through-type stepping motor; 56. Liquid adding specific fixture; 57. Third proximity sensor; 58. Second connecting plate;

[0039] 6. Visual inspection module; 61. Industrial array camera; 62. Variable-magnification telecentric lens; 63. Connectors;

[0040] 7. Automatic screen flipping mechanism; 71. Display screen; 72. Screen fixing plate; 73. Screen cover; 74. Driven wheel; 75. Pin shaft; 76. Miniature bearing; 77. Fixed housing; 78. Second planetary reduction stepping motor; 79. Driving wheel; 710. Belt; 711. Fourth proximity sensor; 712. Membrane switch;

[0041] 8. Control module;

[0042] 9. Fixture tray. DETAILED DESCRIPTION

[0043] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0044] See also Figure 1 - 2. The utility model provides a laboratory automatic micro-droplet instrument, which includes a cabinet 1, an XY axial moving mechanism 2, an automatic clamping mechanism 3, a lifting baffle mechanism 4, a micro-droplet mechanism 5, a visual detection module 6, an automatic screen flipping mechanism 7, and a control module 8; the structure and function of each mechanism or module are described in detail below.

[0045] See also Figure 1-2The cabinet 1 is processed by sheet metal technology and has a solid structure to achieve reliable installation and fixation of each functional module. The interior of the cabinet 11 is divided into two layers by the support plate 12. The electrical installation board 13 is located above the support plate 12. The upper layer is arranged with a lifting baffle mechanism 4, a micro-droplet mechanism 5, a visual detection module 6, an automatic screen flip mechanism 7, and a control module 8. The lower part is arranged with an XY axial movement mechanism 2; the front of the cabinet is opened with an observation window 14 and a fixture plate ejection outlet 15, and adjustable support seats 16 are installed at the four corners of the bottom for easy placement and positioning.

[0046] See also Figure 3 The specific implementation of the XY axial moving mechanism 2 is completed by a linear motor module, which mainly includes a stator module, a rotor module, a brush, a grating ruler, a Hall sensor, a linear guide rail and other structures, which will not be described here; in this embodiment, the X-axis linear motor module 21 and the Y-axis linear motor module 22 are cross-distributed, The X-axis linear motor module 21 is connected to the bottom of the cabinet 1 through fasteners, and its slider 211 is connected to the Y-axis linear motor module 22. The slider 221 of the Y-axis linear motor module 22 is connected to the automatic clamping mechanism 3, and the fixture disk 9 is fixed on it. Through the XY axial moving mechanism 2, the fixture disk 9 can not only be accurately transferred in the micro-liquid titration, visual inspection, and clamping stations, but also accurately move and position according to the set coordinates during dripping to achieve precise dripping; the X-axis linear motor module 21 is equipped with an X-axis positive limit switch 212, an X-axis negative limit switch 214, and an X-axis origin switch 213, which serve as electronic limit and zeroing devices for the movement of the slider, and the same is true for the Y-axis linear motor module 22.

[0047] See also Figure 4Exploded view, the automatic clamp mechanism 3 includes a clamping positioning device 31 and an automatic pop-up device 32; the clamping positioning device 31 is used to accurately fix the fixture plate 9, and its specific implementation method is: according to the size and structure of the fixture plate 9, a clamp body 311 and a clamp baffle 313 adapted thereto are designed, grooves are provided on the left and right sides of the clamp body 311, and a spring 312 is placed in the groove. The clamp baffle 313 is slidably connected to the clamp body 311 through the spring 312. When subjected to external force, the spring 312 stretches and the two can be separated. After the external force is lost, the spring 312 is released. The spring 312 contracts to provide a pressing force to make the two fit tightly together, thereby fixing the fixture plate 9. The wire diameter, length, and outer diameter of the spring 33 are selected based on experience and force analysis calculations; the fixture body 311 is equipped with an LED light board 314 to provide light for the visual inspection module 6. An LED lampshade 315 is provided on the upper part of the LED light board 314 for placing the fixture plate 9 to prevent the LED light board 314 from directly contacting the fixture plate 9 and causing surface scratches. At the same time, a left-right symmetrical heat sink 316 is bonded to the lower part to provide ventilation and heat dissipation for the LED light board 314; it pops up automatically The device 32 is used to pop the clamping and positioning device 31 out of the cabinet 1, and perform the clamping operation outside to improve the convenience of operation. The specific implementation method is: the "stepping motor + gear / bar" transmission method is used to realize the pop-up action. The support shell 321 is processed by sheet metal technology to provide an installation basis for various components. The first planetary reduction stepper motor 323 is installed inside the support shell 321, and its output shaft is connected to the micro gear 324. A rack 325 with the same module as the micro gear 324 is installed at the corresponding position at the bottom of the clamp body 311, and the two are meshed for transmission. Micro slide rails 322 are symmetrically arranged on the left and right sides of the upper part of the supporting shell 321. The clamping and positioning device 31 and the automatic pop-up device 32 are slidably connected through the micro slide rails 322. When the first planetary reduction stepper motor 323 is started, the clamping and positioning device 31 is moved along the micro slide rails 322 through the engagement of the micro gear 324 and the rack 3325. A first proximity sensor 326 is installed at the corresponding position at the rear of the supporting shell 321, which is used to sense the moving state of the clamping and positioning device 31, thereby controlling the action of the first planetary reduction stepper motor 323.

[0048] See also Figure 5The lifting baffle mechanism 4 is an auxiliary mechanism, and its function is to close or open the fixture tray ejection outlet 15 of the cabinet 1. The specific implementation method is: the first connecting plate 42 is rigidly connected to the cabinet 11, a micro-electric push rod 41 is installed at the first connecting plate 42, and a movable baffle 43 is installed at the end of the electric push rod 41. A second proximity sensor 45 is set at the initial position and connected to the cabinet 11 through a connecting piece 46. A hollow shell 44 is installed at the fixture tray ejection outlet 15, and a guide groove is arranged inside the hollow shell 44. The movable baffle 43 is slidably connected to the hollow shell 44 through the guide groove; the movable baffle 43 is driven to rise and fall in the hollow shell 44 through the contraction and extension movement of the micro-electric push rod 41. When the automatic clamping mechanism 3 pops out, the micro-electric push rod 41 contracts, driving the movable baffle 43 to rise, and providing a channel for the automatic clamping mechanism 3 to pop out; when the automatic clamping mechanism 3 enters the instrument, the micro-electric push rod 41 is in the extended position, and the movable baffle 43 just closes the cabinet ejection outlet 15.

[0049] See also Figure 6 The micro-droplet mechanism 5 is divided into two parts: liquid injection and liquid addition; in the liquid injection part, the precision injection pump 51 quantitatively injects the test solution from the stock solution reagent bottle 53 into the liquid addition needle 54 through the capillary 52; the liquid addition part adopts a through-type stepping motor 55, and the end is connected with a specific liquid addition fixture 56, and the liquid addition needle 54 is fixed on the specific liquid addition fixture 56. The through-type stepping motor 55 converts circular motion into linear motion, and then drives the specific liquid addition fixture 56 and the liquid addition needle 54 to move up and down to complete the liquid addition action; in particular, a third proximity sensor 57 is provided at the tail end of the through-type stepping motor 55 for sensing the movement state of the motor shaft to ensure the accuracy and safety of the liquid addition process. It is connected to the electrical installation board 13 through the second connecting plate 58, and the precision injection pump 51, the stock solution reagent bottle 53, and the through-type stepping motor 55 are also arranged on the electrical installation board 13.

[0050] See also Figure 7, the visual inspection module 6 is arranged in the upper left part of the cabinet, and is arranged opposite to the micro-droplet mechanism 5, that is, the center lines of the two coincide, and its function is to identify and detect the presence and amount of liquid in each groove of the fixture plate after the dripping is completed. The function of the visual inspection module 6 is to identify and detect the liquid in each groove of the fixture plate 9 after the dripping is completed, to ensure that the liquid exists in each groove and the amount of liquid meets the preset requirements; including: industrial array camera 61 (model: Hikvision MV-CS200-10GM / C), zoom telecentric lens 62 (model: Hikvision GM1084 / 75), connector 63; the industrial array camera 61 is connected to the cabinet 11 through the connector 63, and the zoom telecentric lens 62 is installed at the end; the industrial array camera 61 is responsible for capturing the image of each groove in the fixture plate, and the zoom telecentric lens 62 can perform zoom and telecentric processing on the captured image to ensure that the image can remain clear and distorted at different magnifications, and the detection photo is displayed on the LED screen 71 for easy observation by the operator.

[0051] The automatic screen flipping mechanism 7 is arranged at the upper left part of the cabinet. This special function reduces the steps for the operator to manually adjust the display screen, so that the instrument can automatically display the best viewing angle when it is turned on, thereby optimizing the user's operating experience. Figure 8 Exploded diagram, the automatic screen flipping mechanism 7 adopts the "stepping motor + belt" transmission method to realize the flipping action, and its specific implementation method is: the fixed shell 77 is connected to the cabinet 11 by screws to ensure the stability of the whole mechanism, and miniature bearings 76 are installed on the left and right sides thereof, and a second planetary reduction stepper motor 78 is installed at the bottom. The output shaft of the second planetary reduction stepper motor 78 is connected to the driving wheel 79, and the power and speed are transmitted to the driven wheel 74 through the belt 710; the driven wheel 74 is installed on the protruding cylinder on the left side of the screen fixing plate 72, and a circular groove is opened on the right side of the screen fixing plate 72 for installing the pin shaft 75. The protruding cylinder on the left side of the screen fixing plate 72 and the pin shaft 75 installed on the right side are respectively interference fit with the miniature bearings 76 on both sides of the screen fixing plate 72 through the top screw; the screen cover plate 7 The LED display screen 71 is fixed on the screen fixing plate 72 by means of a connection method of a buckle and a slot; a fourth proximity sensor 711 is arranged at the fixed housing 77, the top of which is flush with the plane of the fixed housing 77, and is used to sense the position of the screen fixing plate 72 to ensure the accuracy of the flipping action; a row of membrane switches 712 is arranged at the front of the fixed housing 77 to control the start and stop and operation of the instrument; when the instrument is turned on, the second planetary reduction stepper motor 78 is started and rotates according to the set speed and time, and the driving wheel 79 transmits the motion to the driven wheel 74 through the belt 710, thereby driving the display screen to automatically flip to a 60° position, so as to facilitate the observation of the identification photo of the liquid in the fixture plate. When the instrument is turned off, the screen automatically flips to the initial position, that is, flush with the horizontal plane of the fixed housing 77.

[0052] See also Figure 1The control module 8 adopts PLC / LED display screen automatic control and visual human-computer interaction; PLC is responsible for data collection, program operation, and command output of the above-mentioned functional modules, and the LED display screen monitors the system operation status and visual photos, which is vivid and intuitive.

[0053] The utility model provides a laboratory automatic micro-droplet instrument. When it is used, the operator clicks the "start" button at the membrane switch 712, and the instrument starts to initialize. During the initialization process, the automatic screen flipping mechanism 7 runs first, and the LED display screen 71 is automatically flipped to the 60° position and remains stationary. At the same time, the micro-electric push rod 41 in the lifting baffle mechanism 4 contracts, driving the end movable baffle 43 to rise, thereby providing a channel for the automatic clamping mechanism 3 to pop out; then the XY axial moving mechanism 2 runs along the X and Y axes, and the fixture plate 9 on the automatic clamping mechanism 3 is ejected to the clamping station outside the cabinet 1. At this time, the fixture plate 9 is manually placed at the specified position of the automatic clamping mechanism 3, and the "run" button at the membrane switch 712 is clicked, the automatic clamping mechanism 3 brings the fixture plate 9 into the cabinet 1, and the micro-electric push rod 41 immediately drives the end movable baffle 43 to drop to the initial position; the instrument starts to enter the automatic working mode. The working process is as follows: the XY axial moving mechanism 2 carries the fixture plate 9 to move to the initial position of the micro-droplet mechanism 5, starting from the groove at the first row and first column of the fixture plate 9, quantitative liquid is added to each groove in turn according to the set X and Y coordinates. During this process, the instrument accurately controls the amount of each drop of liquid through the precision injection pump 51 to ensure that each groove can get an accurate dose of liquid; when all the grooves on the fixture plate 9 are filled with liquid, the XY axial moving mechanism 2 transfers the fixture plate 9 to the visual inspection module 6, and identifies and detects the liquid in each groove to ensure that the liquid in each groove exists and the liquid volume meets the preset requirements. If the liquid volume does not meet the requirements, it returns to the micro-droplet module 5 for liquid replenishment, and the cycle continues until the liquid volume in each groove meets the preset requirements; after the final detection is completed, the automatic clamping mechanism 3 ejects the fixture plate 9 from the cabinet 1, and the instrument will issue an alarm prompt to inform the user that the liquid addition process has been completed.

[0054] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Ordinary technicians in this technical field should understand that without departing from the spirit and scope of the technical solution of the present invention, modifications and replacements of some of the technical features therein are all within the protection scope of the present invention.

[0055] The embodiments described above can be further combined or replaced, and the embodiments are only descriptions of preferred embodiments of the present invention, and do not limit the concept and scope of the present invention. Without departing from the design concept of the present invention, various changes and improvements made by ordinary technicians in this field to the technical solution of the present invention belong to the protection scope of the present invention. The protection scope of the present invention is given by the attached claims and any equivalents thereof.

Claims

1. A laboratory automatic micro-droplet instrument, characterized in that: include: A cabinet (1), wherein the cabinet body (11) of the cabinet (1) is divided into an upper and lower layer by a support plate (12); an electrical installation plate (13) is detachably connected above the support plate (12); a lifting baffle mechanism (4), a micro-droplet mechanism (5), a visual detection module (6), an automatic screen flipping mechanism (7), and a control module (8) are arranged on the upper layer; an XY axial movement mechanism (2) is installed on the lower layer; and an observation window (14) and a fixture plate ejection outlet (15) are provided at the front of the cabinet (1).

2. A laboratory automatic micro-droplet instrument according to claim 1, characterized in that: The X-axis linear motor module (21) and the Y-axis linear motor module (22) in the XY axial movement mechanism (2) are arranged in a cross-shaped arrangement; the bottom of the X-axis linear motor module (21) is connected to the cabinet (1), and the top is slidably connected to the X-axis slider (211); the Y-axis linear motor module (22) is mounted on the X-axis slider (211), and the top is slidably connected to the Y-axis slider (221); and the Y-axis slider (221) is mounted with an automatic clamping mechanism (3) for fixing the fixture plate (9).

3. A laboratory automatic micro-droplet instrument according to claim 2, characterized in that: The automatic clamping mechanism (3) comprises a clamping positioning device (31) and an automatic pop-up device (32); the clamping positioning device (31) has grooves on both sides of the clamp body (311), the spring (312) is placed in the groove, the clamp baffle (313) is slidably connected to the clamp body (311) through the spring (312), an LED light board (314) is installed on the upper part of the clamp body (311), an LED lamp cover (315) is provided on the upper part of the LED light board (314), and a left-right symmetrical heat sink (316) is bonded to the lower part, and the fixture plate (314) is provided with a plurality of LED lamps (315). 9) is placed on the LED lamp cover (315); micro slide rails (322) are symmetrically installed on the left and right sides of the support shell (321) in the automatic pop-up device (32), a first planetary reduction stepping motor (323) is installed inside, a micro gear (324) is installed on the output shaft of the first planetary reduction stepping motor (323), a rack (325) is installed at the bottom of the clamp body (311), the micro gear (324) is meshed with the rack (325), and a first proximity sensor (326) is installed at an appropriate position on the rear of the support shell (321).

4. A laboratory automatic micro-droplet instrument according to claim 3, characterized in that: The clamping and positioning device (31) is slidably connected to the automatic pop-up device (32) via the micro slide rail (322).

5. A laboratory automatic micro-droplet instrument according to claim 1, characterized in that: The first connecting plate (42) in the lifting baffle mechanism (4) is rigidly connected to the cabinet (11); a micro electric push rod (41) is installed at the first connecting plate (42); the end of the micro electric push rod (41) is connected to a movable baffle (43); a second proximity sensor (45) is arranged at an initial position; a hollow shell (44) is installed at the ejection outlet (15) of the fixture plate; a guide groove is arranged inside the hollow shell; and the movable baffle (43) is slidably connected to the hollow shell (44) via the guide groove.

6. A laboratory automatic micro-droplet instrument according to claim 1, characterized in that: The micro-droplet mechanism (5) comprises two parts: a liquid injection part and a liquid addition part. In the liquid injection part, a precision injection pump (51) quantitatively injects a test solution from a stock solution reagent bottle (53) into a liquid addition needle (54) through a capillary channel (52). The liquid addition part adopts a through-type stepping motor (55), the end of which is connected to a liquid addition specific fixture (56) and the liquid addition needle (54). A third proximity sensor (57) is arranged at the tail end and is connected to an electrical installation board (13) through a second connecting board (58). The precision injection pump (51), the stock solution reagent bottle (53), and the through-type stepping motor (55) are all arranged on the electrical installation board (13).

7. The laboratory automatic micro-droplet instrument according to claim 1, characterized in that: The visual inspection module (6) comprises: an industrial area array camera (61), a variable-magnification telecentric lens (62), and a connecting piece (63); the industrial area array camera (61) is connected to the cabinet (11) via the connecting piece (63), and the variable-magnification telecentric lens (62) is installed at the end.

8. The laboratory automatic micro-droplet instrument according to claim 1, characterized in that: The fixed housing (77) in the automatic screen flipping mechanism (7) is connected to the cabinet (11) by screws, and micro bearings (76) are installed on the left and right sides. A second planetary reduction stepping motor (78) is installed at the bottom. The output shaft of the second planetary reduction stepping motor (78) is connected to the driving wheel (79), and the power and rotation speed are transmitted to the driven wheel (74) through the belt (710); the driven wheel (74) is installed on the protruding cylinder on the left side of the screen fixing plate (72), and the right side of the screen fixing plate (72) is provided with a circular groove for installing a pin shaft (75). The protruding cylinder on the left side of the screen fixing plate (72) and the pin shaft (75) installed on the right side are respectively interference-fitted with the micro bearings (76) on both sides of the screen fixing plate (72) through top screws; the screen cover plate (73) fixes the LED display screen (71) on the screen fixing plate (72) by means of a buckle and a slot connection; a row of membrane switches (712) is arranged at the front of the fixed housing (77).

9. The laboratory automatic micro-droplet instrument according to claim 1, characterized in that: The control module (8) uses a PLC / LED display screen to achieve automated control and visual interaction.

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