Anti-damage culture equipment for NK cells

Abstract

The utility model discloses damage-proof culture equipment for NK cells, which comprises a constant-temperature box body, a storage disc is slidably arranged in the constant-temperature box body, a culture dish mechanism is clamped at the upper end of the storage disc, the culture dish mechanism comprises a culture box, a protective cover is arranged at the upper end of the culture box in a threaded manner, and the protective cover is connected with the storage disc in a threaded manner. A magnetic suction cover is hinged to the upper end of the protective cover, and a sealing ring is fixedly arranged on one side of the outer surface of the magnetic suction cover. According to the culture dish, an existing culture dish is improved, the small hinged cover and the observation opening are formed in the upper end of the protective cover, the hinged cover is arranged in a magnetic attraction mode, when only the condition of internal cells needs to be attracted or observed, the magnetic attraction cover is opened, vibration generated during opening is reduced, and the cell survival rate is increased; the device is provided with the constant-temperature box mechanism and the culture dish mechanism, the arrangement of the constant-temperature box mechanism facilitates the placement of a plurality of culture dishes, facilitates the adjustment of the temperature required by cells in the culture dishes, and facilitates the improvement of the cell survival rate.

Description

Technical Field

[0001] The utility model relates to the technical field of culture equipment, in particular to a damage-resistant culture equipment for NK cells. Background Art

[0002] NK cells, also known as "natural killer cells", are important immune cells in the body. They are not only related to anti-tumor, anti-viral infection and immune regulation, but also participate in the occurrence of hypersensitivity reactions and autoimmune diseases in some cases. They can identify target cells and kill mediators. When NK cells are cultured in the laboratory, culture dishes are usually used to culture them.

[0003] Traditional culture dishes are usually divided into two parts, a device box and a protective cover. In order to improve the sealing, the device box and the protective cover are usually connected with threads. However, during the culture process, the culture dish needs to be taken out frequently to observe and detect the internal cells. Traditional culture dishes need to be opened by turning up and down, which will generate large vibrations. If this happens frequently, the internal cells will be severely damaged.

[0004] Therefore, the utility model provides an anti-damage culture device for NK cells to solve the problems raised in the above background technology. Utility Model Content

[0005] In view of the defects in the prior art, the utility model provides an anti-damage culture device for NK cells. The device improves the existing culture dish and opens a small hinged cover and an observation port on the upper end of the protective cover. The hinged cover is arranged by magnetic attraction. When it is only necessary to absorb or observe the internal cells, the magnetic attraction cover can be opened to reduce the vibration generated when opening, so as to improve the cell survival rate.

[0006] Preferably, an anti-damage culture device for NK cells comprises a thermostat body, a storage tray is slidably arranged inside the thermostat body, and a culture dish mechanism is clamped on the upper end of the storage tray. The thermostat body is conducive to keeping the cells at a certain constant temperature and reducing cell damage, the storage tray is conducive to the clamping and placement of the culture dish mechanism, and the culture dish mechanism is conducive to the installation and cultivation of cells.

[0007] The culture dish mechanism includes a culture box, a protective cover is threadedly provided on the upper end of the culture box, a magnetic cover is hingedly provided on the upper end of the protective cover, and a sealing ring is fixedly provided on one side of the outer surface of the magnetic cover. The culture box is conducive to the installation of cells, the protective cover is conducive to preventing external dust and bacteria from entering the interior, the magnetic cover is conducive to opening and closing the culture dish mechanism, and is conducive to reducing the vibration generated when the culture dish mechanism is opened, and the sealing ring is conducive to strengthening the sealing performance.

[0008] Preferably, an ultraviolet disinfection lamp is fixedly arranged on the top surface of the thermostat body, and a temperature sensor is fixedly arranged on the inner wall of the rear side of the thermostat body. The ultraviolet disinfection lamp is convenient for placing the culture dish mechanism inside for disinfection and sterilization after use, and the temperature sensor is convenient for sensing the internal temperature and controlling the internal temperature of the thermostat body.

[0009] Preferably, a No. 1 magnetic attraction ring is fixedly provided at the lower end of the magnetic attraction cover, and a No. 2 magnetic attraction ring is fixedly provided at the middle position of the inner surface of the protective cover. The provision of the No. 1 magnetic attraction ring is conducive to the use with the No. 2 magnetic attraction ring, and is conducive to the magnetic attraction fixation of the magnetic attraction cover.

[0010] Preferably, a plurality of clamping plates are fixedly arranged on the upper end of the storage tray, and sliding blocks are fixedly arranged on both sides of the storage tray. The clamping plates are conducive to the clamping and placement of the culture dish mechanism, and the sliding blocks are conducive to the storage tray sliding inside the slide groove.

[0011] Preferably, a protective door is hingedly provided at the front end of the thermostat body, and an observation window is fixedly provided at the middle of the front end of the protective door. The protective door is conducive to protecting the interior, and the observation window is conducive to observing the internal situation.

[0012] Preferably, suction cups are fixedly arranged at the four corners of the lower end of the thermostat body, and a plurality of slide grooves are provided on the inner walls of both sides of the thermostat body. The arrangement of the suction cups is conducive to improving the friction between the device and the ground, and is conducive to enhancing the stability of the device.

[0013] Preferably, a display screen is fixedly arranged at one side of the upper end of the thermostat body. The arrangement of the display screen is conducive to controlling the thermostat.

[0014] The beneficial effects of the utility model are embodied in:

[0015] 1. The utility model proposes an anti-damage culture device for NK cells. Traditional culture dishes are usually divided into two parts, a device box and a protective cover. In order to improve the sealing, the device box and the protective cover are usually connected by threads. However, during the culture process, the culture dish needs to be taken out from time to time to observe and detect the internal cells. The traditional culture dish needs to be turned up and down to open, which will generate large vibrations when opened. If this is often the case, the internal cells will be greatly damaged. The device improves the existing culture dish and opens a small hinged cover and observation port on the upper end of the protective cover. The hinged cover is set by magnetic suction. When it is only necessary to absorb or observe the internal cells, the magnetic suction cover can be opened, which reduces the vibration generated when opening and improves the cell survival rate.

[0016] 2. The utility model proposes an anti-damage culture device for NK cells. The device is provided with a constant temperature box mechanism and a culture dish mechanism. The setting of the constant temperature box mechanism is conducive to the placement of multiple culture dishes, to the adjustment of the temperature required by the cells inside the culture dishes, to the improvement of the cell survival rate, and to the storage of the culture dishes, which is convenient for use. The setting of the culture dish mechanism is conducive to the cultivation of cells, and is also conducive to reducing the vibration amplitude when opening, reducing cell damage, and facilitating use. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the specific implementation of the utility model or the technical solution in the prior art, the following is a brief introduction to the drawings required for the specific implementation or the prior art description. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, each element or part is not necessarily drawn according to the actual scale.

[0018] Figure 1 An axonometric diagram provided for an embodiment of the utility model;

[0019] Figure 2 for Figure 1 The expanded axonometric diagram shown;

[0020] Figure 3 for Figure 1 The bottom-up axonometric diagram shown;

[0021] Figure 4 for Figure 1 An axonometric diagram of the petri dish mechanism shown;

[0022] Figure 5 for Figure 1 An expanded axonometric diagram of the culture dish mechanism shown;

[0023] Figure 6 for Figure 1 The front axonometric diagram shown;

[0024] In the accompanying drawings, 1. constant temperature box mechanism; 2. culture dish mechanism; 101. constant temperature box body; 102. protective door; 103. observation window; 104. slide; 105. storage tray; 106. slider; 107. snap-on tray; 108. suction cup; 109. ultraviolet disinfection lamp; 110. temperature sensor; 111. display screen; 201. culture box; 202. protective cover; 203. magnetic cover; 204. sealing ring; 205. magnetic ring No. 1; 206. magnetic ring No. 2. DETAILED DESCRIPTION

[0025] The following embodiments of the technical solution of the utility model are described in detail in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the utility model, and are therefore only used as examples, and cannot be used to limit the protection scope of the utility model.

[0026] It should be noted that, unless otherwise specified, the technical terms or scientific terms used in this application should have the common meanings understood by technicians in the field to which the utility model belongs.

[0027] Reference Figure 1-3 6. An embodiment of the utility model provides: an anti-damage culture device for NK cells, comprising a constant temperature box mechanism 1, the constant temperature box mechanism 1 comprises a constant temperature box body 101, a storage tray 105 is slidably arranged inside the constant temperature box body 101, an ultraviolet disinfection lamp 109 is fixedly arranged on the top surface of the constant temperature box body 101, a temperature sensor 110 is fixedly arranged on the inner wall of the rear side of the constant temperature box body 101, a plurality of clamping trays 107 are fixedly arranged on the upper end of the storage tray 105, sliders 106 are fixedly arranged on both sides of the storage tray 105, a protective door 102 is hingedly arranged at the front end of the constant temperature box body 101, an observation window 103 is fixedly arranged at the middle position of the front end of the protective door 102, suction cups 108 are fixedly arranged at the four corners of the lower end of the constant temperature box body 101, a plurality of slide grooves 104 are opened on the inner walls on both sides of the constant temperature box body 101, and a display screen 111 is fixedly arranged on one side of the upper end of the constant temperature box body 101.

[0028] The setting of the thermostat mechanism 1 is conducive to the placement of multiple culture dishes, to the adjustment of the temperature required by the cells inside the culture dishes, to improving the cell survival rate, and to the storage and collection of the culture dishes, making it easy to use. The storage tray 105 is conducive to the use in conjunction with the snap-in tray 107, which is conducive to the snap-in placement of the culture dish mechanism 2. The setting of the ultraviolet disinfection lamp 109 is conducive to the placement of the culture dish mechanism 2 inside for disinfection and sterilization after use. The setting of the temperature sensor 110 is conducive to sensing the internal temperature and controlling the internal temperature of the thermostat body 101. The protective door 102 is conducive to protecting the interior. The setting of the observation window 103 is conducive to observing the internal situation. The setting of the suction cup 108 is conducive to increasing the friction between the device and the ground, which is conducive to enhancing the stability of the device. The setting of the display screen 111 is conducive to the use in conjunction with the thermostat and is conducive to controlling the internal temperature of the thermostat.

[0029] Reference Figure 2 and 4-5, a culture dish mechanism 2 is snap-connected to the upper end of the storage tray 105, the culture dish mechanism 2 comprises a culture box 201, a protective cover 202 is threadedly provided on the upper end of the culture box 201, a magnetic cover 203 is hingedly provided on the upper end of the protective cover 202, a sealing ring 204 is fixedly provided on one side of the outer surface of the magnetic cover 203, a No. 1 magnetic ring 205 is fixedly provided on the lower end of the magnetic cover 203, and a No. 2 magnetic ring 206 is fixedly provided on the middle position of the inner surface of the protective cover 202.

[0030] The device improves the existing culture dish. The culture dish mechanism 2 is provided with a small magnetic cover 203 and an observation port on the upper end of the protective cover 202. The magnetic cover 203 is hingedly arranged. When it is only necessary to absorb or observe the internal cell conditions, the magnetic cover 203 can be opened to reduce the vibration generated when opening and improve the cell survival rate. The culture box 201 is conducive to the installation of cells, the protective cover 202 is conducive to preventing external dust and bacteria from entering the interior, the magnetic cover 203 is conducive to the opening and closing of the culture dish mechanism 2, and is conducive to reducing the vibration generated when the culture dish mechanism 2 is opened. The setting of the No. 1 magnetic suction ring 205 is conducive to the use with the No. 2 magnetic suction ring 206, which is conducive to the magnetic suction fixation of the magnetic suction cover 203, and the sealing ring 204 is conducive to enhancing the sealing.

[0031] Working principle: When the device is used, the cells are placed in the culture dish mechanism 2, and then the culture dish mechanism 2 is placed on the storage tray 105 through the snap-on tray 107, and the protective door 102 can be closed to maintain a constant internal temperature to prevent internal cells from being damaged due to improper temperature. When it needs to be taken out for use, the storage tray 105 can be taken out as a whole, and then the magnetic cover 203 on the upper end of the protective cover 202 on the upper end of the culture dish mechanism 2 can be opened to absorb the internal bacteria or perform other operations, thereby slowing down the shaking caused by opening, reducing the cell damage rate, and facilitating use.

[0032] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents. These modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the utility model, and they should all be included in the scope of the claims and specification of the utility model.

Claims

1. A damage-resistant culture device for NK cells, comprising a constant temperature box mechanism (1), characterized in that: The thermostat mechanism (1) comprises a thermostat body (101), a storage tray (105) is slidably arranged inside the thermostat body (101), and a culture dish mechanism (2) is clamped and arranged on the upper end of the storage tray (105); The culture dish mechanism (2) comprises a culture box (201), the upper end of the culture box (201) is threadedly provided with a protective cover (202), the upper end of the protective cover (202) is hingedly provided with a magnetic cover (203), and one side of the outer surface of the magnetic cover (203) is fixedly provided with a sealing ring (204).

2. The damage-resistant culture device for NK cells according to claim 1, characterized in that: An ultraviolet disinfection lamp (109) is fixedly arranged on the inner top surface of the thermostatic box body (101), and a temperature sensor (110) is fixedly arranged on the rear inner wall of the thermostatic box body (101).

3. The damage-resistant culture device for NK cells according to claim 1, characterized in that: A first magnetic attraction ring (205) is fixedly disposed at the lower end of the magnetic attraction cover (203), and a second magnetic attraction ring (206) is fixedly disposed at the middle position of the inner surface of the protective cover (202).

4. The damage-resistant culture device for NK cells according to claim 1, characterized in that: A plurality of clamping plates (107) are fixedly arranged on the upper end of the storage plate (105), and sliding blocks (106) are fixedly arranged on both sides of the storage plate (105).

5. The damage-resistant culture device for NK cells according to claim 1, characterized in that: A protective door (102) is hingedly provided at the front end of the thermostatic box body (101), and an observation window (103) is fixedly provided at the middle position of the front end of the protective door (102).

6. The damage-resistant culture device for NK cells according to claim 1, characterized in that: Suction cups (108) are fixedly arranged at the four corners of the lower end of the thermostatic box body (101), and a plurality of slide grooves (104) are provided on the inner walls on both sides of the thermostatic box body (101).

7. The damage-resistant culture device for NK cells according to claim 4, characterized in that: A display screen (111) is fixedly disposed on one side of the upper end of the thermostat body (101).

Images