Liquid adding mechanism and liquid adding equipment
By designing a liquid adding mechanism including a fixed bracket, a liquid adding needle, a connecting mechanism and a driving mechanism, the shortcomings of the existing liquid adding equipment in liquid addition are solved, and a stable and efficient liquid adding process is achieved.
Patent Information
- Application Number
- CN202323640533.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2023-12-29
- Publication Date
- 2025-02-14
- Estimated Expiration
- 2033-12-29
AI Technical Summary
Existing sample liquid addition equipment for freezing and preservation of liquid nitrogen needs further improvement to better achieve liquid addition.
A liquid-adding mechanism is provided, including a first fixing bracket, a liquid-adding needle, a first connecting mechanism and a first driving mechanism. Through the coordinated operation of these components, the movement of the liquid-adding needle and the stable addition of liquid are achieved.
The liquid adding mechanism can be used for single-channel or multi-channel liquid addition, maintaining stability during liquid addition and improving the efficiency and quality of sample preparation.
Smart Images

Figure CN222469101U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to an experimental instrument, in particular to a liquid adding mechanism and liquid adding equipment. Background Art
[0002] Liquid nitrogen freezing technology is widely used in the low-temperature storage of animal sperm, cells, vaccines, etc. The sample adding equipment used for liquid nitrogen freezing in the prior art needs to be further improved. Utility Model Content
[0003] Purpose of the utility model: In order to solve the problems of the prior art, the utility model provides a liquid adding mechanism and a liquid adding device. The liquid adding mechanism of the present application can be better used for adding liquid.
[0004] Technical solution: The utility model provides a liquid adding mechanism, comprising a first fixing bracket, the first fixing bracket comprising at least one or more fixing units, the fixing units extending along a first direction, and the fixing units having a receiving cavity extending along the first direction;
[0005] A liquid adding needle, the liquid adding needle is connected to the fixing unit and communicates with the accommodating chamber;
[0006] a first connecting mechanism, the first connecting mechanism being connected to the first fixing bracket;
[0007] A first driving mechanism, wherein the first driving mechanism is connected to the first connecting mechanism, and the first driving mechanism drives the first connecting mechanism to move along the first direction, thereby driving the first fixing bracket and the liquid-filling needle to move along the first direction.
[0008] In some embodiments, the fixing unit has a first mounting hole, and the accommodating cavity is in communication with the first mounting hole.
[0009] In some embodiments, the first driving mechanism includes a first driving motor, a first driving wheel and a first driving belt; the first driving belt is connected to the first driving wheel, and the first driving motor drives the first driving wheel to rotate, thereby driving the first driving belt to move along the first direction.
[0010] In some embodiments, the first connection mechanism includes a first connection block, and the first connection block is connected to the first fixing bracket;
[0011] The second connecting block is connected to the first connecting block, and the second connecting block has a first connecting groove, the first driving belt passes through the first connecting groove, and the first driving belt is connected to the second connecting block.
[0012] In some embodiments, the first connecting mechanism includes a first slide rail, the first connecting block is mounted on the first slide rail through a slide groove, and the first slide rail is arranged parallel to the first driving belt.
[0013] In some embodiments, the liquid adding mechanism further includes a first protection mechanism, and the first protection mechanism is disposed on the outer periphery of the first slide rail and the first driving belt.
[0014] In some embodiments, the first protection mechanism includes a first frame and a protection plate disposed on one side of the first frame, and the first connecting block passes through a slide groove on the protection plate and is connected to the first slide rail.
[0015] An embodiment of the present application further provides a liquid adding device, comprising the above-mentioned liquid adding mechanism, wherein the liquid adding mechanism is used to deliver fluid.
[0016] In some embodiments, the liquid adding device further includes a second driving mechanism, which is connected to the liquid adding mechanism and is used to drive the liquid adding mechanism to move along a third direction.
[0017] In some embodiments, the second driving mechanism is connected to the liquid adding mechanism via a second connecting mechanism, the second connecting mechanism includes a connecting arm, a connecting seat and a second slide rail, the second slide rail extends along a third direction; one end of the connecting arm is connected to the liquid adding mechanism, and the other end of the connecting arm is fixed to the connecting seat; the connecting seat is mounted on the second slide rail, and the connecting seat can slide along the second slide rail.
[0018] In some embodiments, the second driving mechanism includes a second driving motor, a second driving wheel connected to the output end of the driving motor, and a second driving belt arranged on the outer periphery of the second driving wheel, and the second driving belt is fixed to the connecting seat.
[0019] In some embodiments, the connecting seat has a second connecting groove, the second connecting groove extends along a second direction, and the connecting arm includes a clamping block, and the clamping block is located in the second connecting groove.
[0020] In some embodiments, the connecting arm has a gap groove near the connecting seat.
[0021] In some embodiments, the connecting seat is connected to the second slide rail via a sliding block.
[0022] In some embodiments, the liquid adding device further comprises a liquid delivery mechanism, the liquid delivery mechanism is connected to the liquid adding mechanism, the liquid delivery mechanism comprises at least one liquid delivery unit, and the liquid delivery mechanism is used to control the amount of liquid delivered into the liquid adding mechanism.
[0023] In some embodiments, a support mechanism is included, the support mechanism includes a first support plate, and the first support plate is arranged at both ends of the second slide rail;
[0024] a second support plate, the second support plate being disposed below the second slide rail and connected to the second slide rail;
[0025] A first support rod, both ends of which are connected to the first support plate, and the first support rod is used to fix the liquid delivery mechanism.
[0026] Beneficial effects: Compared with the prior art, the present application provides a liquid adding mechanism and liquid adding equipment, including a first fixed bracket, the first fixed bracket includes at least one or more fixed units, the fixed units extend along the first direction, and the fixed units have a receiving cavity extending along the first direction; a liquid adding needle, the liquid adding needle is connected to the fixed unit, and the liquid adding needle is connected to the receiving cavity; a first connecting mechanism, the first connecting mechanism is connected to the first fixed bracket; a first driving mechanism, the first driving mechanism is connected to the first connecting mechanism, the first driving mechanism drives the first connecting mechanism to move along the first direction, and then drives the first fixed bracket and the liquid adding needle to move along the first direction. The liquid adding mechanism of the present application can be used for liquid addition in a single channel or multiple channels, and maintains stability during the liquid addition process. BRIEF DESCRIPTION OF THE DRAWINGS
[0027] Figure 1 This is a schematic diagram of the structure of the liquid adding mechanism in the embodiment of the present application;
[0028] Figure 2 This is a schematic diagram of the structure of the first connecting mechanism and the first driving mechanism in the embodiment of the present application;
[0029] Figure 3 This is a schematic diagram of the structure of the second driving mechanism of the liquid adding device in the embodiment of the present application;
[0030] Figure 4 This is a schematic diagram of the structure of the second driving mechanism of the liquid adding device in the embodiment of the present application;
[0031] Figure 5 This is a schematic diagram of the structure of the support mechanism of the liquid adding device in the embodiment of the present application;
[0032] Figure 6 This is a schematic diagram of the structure of the support mechanism of the liquid adding device in the embodiment of the present application;
[0033] Figure 7 This is a schematic diagram of the structure of the liquid adding mechanism and the cup body in the embodiment of the present application;
[0034] Figure 8 This is a schematic diagram of the structure of the liquid adding mechanism and the cup body in the embodiment of the present application;
[0035] Figure markings: 1-liquid adding mechanism, 11-first fixed bracket, 110-fixing unit, 1101-accommodating chamber, 1102-first mounting hole, 12-liquid adding needle, 13-first connecting mechanism, 131-first connecting block, 132-second connecting block, 133-first slide rail, 1321-first connecting groove, 14-first driving mechanism, 141-first driving motor, 142-first driving wheel, 143-first driving belt, 15-first protective mechanism, 151-first frame, 152-protective plate; 2-second driving mechanism, 21-second driving motor, 22-second driving wheel, 23-second driving belt, 3-second connecting mechanism, 31-connecting arm, 311-gap groove, 32-connecting seat, 321-second connecting groove, 33-second slide rail. 34-slider; 4-liquid delivery mechanism, 40-liquid delivery unit, 5-support mechanism, 51-first support plate, 52-second support plate, 53-first support rod, 6-cup body. DETAILED DESCRIPTION
[0036] like Figure 1 As shown, the embodiment of the present application provides a liquid adding mechanism 1, including a first fixed bracket 11, the first fixed bracket 11 includes at least one or more fixed units 110, such as in some specific application examples, four parallel fixed units 110 are provided, the fixed units 110 extend along the first direction X, the fixed units 110 are connected to the main structure of the first fixed bracket 11, and the fixed units 110 extend along the first direction X, and can move downward along the first direction X to the cup body 6, and send the sample fluid into the cup body 6 containing liquid nitrogen. In the present application, the first direction X, the second direction Y and the third direction Z intersect each other, and in some specific embodiments, the first direction X, the second direction Y and the third direction Z are perpendicular to each other. In some embodiments, the fixed unit 110 can extend into the filter screen partition in the cup body 6, so that the sample sent by the needle 12 enters the liquid nitrogen, maintains the spherical structure, and the prepared sample is more uniform.
[0037] In some embodiments, the fixed unit 110 is a rod-shaped structure, and the fixed unit 110 has a receiving cavity 1101 extending along the first direction X. The fluid containing the sample is sent to the liquid-adding needle 12 through the connecting pipe, and the receiving cavity 1101 can accommodate the connecting pipe and protect the connecting pipe. In some embodiments, the fixed unit 110 has a first mounting hole 1102, and the first mounting hole 1102 is respectively arranged at both ends of the receiving cavity 1101, and the first mounting hole 102 is connected with the receiving cavity 1101, and the connecting pipe passes through the first mounting hole 1102 and the receiving cavity 1101 to achieve the connection between the connecting pipe and the liquid-adding needle 12, and the connecting pipe is installed in the fixed unit 110 as a whole, avoiding the laying of the pipe from the outside of the structure, resulting in unnecessary folding and bending of the pipe, while protecting the connecting pipe, further ensuring the efficiency of liquid delivery, especially when the amount of liquid added is small, ensuring the smoothness of the connecting pipe at the outlet end can improve the stability of liquid delivery. In some specific embodiments, the number of fixed units 110 of the present application can be set to multiple, and the present application can achieve multi-channel sample addition by setting multiple fixed units 110. The setting of the first fixed bracket 11 of the present application ensures the laying stability and connection stability of the connecting pipeline, and can ensure that when multi-channel sampling is performed, the sample fluid sent out by each needle will not be affected by different positions and moving states. The fixed body of the first fixed bracket 11 is a fixed plate, and the first fixed bracket 11 is provided with a mounting hole in the middle position for fixed connection with the first connecting mechanism 13. The present application improves the liquid adding mechanism 1 and is provided with a plurality of liquid adding channels, which are matched with the number and arrangement of the cup bodies 6 to increase the amount of samples prepared per unit time. In addition, the setting of the motion mechanism is reduced, and there is no need to set a driving mechanism such as the second direction Y to move the liquid adding mechanism 1, thereby simplifying the equipment.
[0038] In some embodiments of the present application, a liquid adding needle 12 is installed at the bottom end of the fixed unit 110, and the liquid adding needle 12 is connected to the accommodating chamber 1101; in a specific application example, a connecting pipe is connected to the liquid adding needle 12 through the accommodating chamber 1101 to deliver the fluid containing the sample to the liquid adding needle 12.
[0039] In some embodiments, the first fixing bracket 11 of the present application is connected to the first driving mechanism 14 through the first connecting mechanism 13, such as Figure 2As shown, the first connection mechanism 13 includes a first connection block 131, which is connected to the first fixed bracket 11; and a second connection block 132, which is connected to the first connection block 131. A protruding structure is provided on the first connection block 131 for fixing with the first fixed bracket 11. The second connection block 131 is provided on one side of the first connection block 131, and the second connection block 132 has a first connection groove 1321, and the first driving belt 143 passes through the first connection groove 1321, and the first driving belt 143 is connected to the second connection block 132. The first connection mechanism 13 also includes a first slide rail 133, and the first connection block 131 is mounted on the first slide rail 133 through a slide groove, and the first connection block 131 can slide along the first slide rail 133 along the first direction X, and the first slide rail 133 is arranged in parallel with the first driving belt 143 to ensure the stable movement of the first connection mechanism 13.
[0040] In some embodiments, the first driving mechanism 14 includes a first driving motor 141, a first driving wheel 142 and a first driving belt 143; the first driving belt 143 is connected to the first driving wheel 142, and the first driving motor 141 drives the first driving wheel 142 to rotate, thereby driving the first driving belt 143 to move along the first direction X, driving the first connecting mechanism 13 to move along the first direction X, and further driving the first fixed bracket 11 and the liquid adding needle 12 to move along the first direction X.
[0041] In some embodiments, the liquid adding mechanism 1 also includes a first protective mechanism 15, which includes a first frame 151 and a protective plate 152 arranged on one side of the first frame 151, the first frame 151 is arranged on the periphery of the first slide rail 133 and the first drive belt 143, the first drive motor 14 is installed on the periphery of the first frame 151, and the first connecting block 131 is connected to the first slide rail 133 through the slide groove on the protective plate 152. The first protective mechanism 15 of the present application can be used to enhance the installation stability of the liquid adding mechanism 1, and to further ensure the safety and operation stability of the liquid adding mechanism 1.
[0042] The embodiment of the present application further provides a liquid adding device, comprising the above-mentioned liquid adding mechanism 1, the liquid adding mechanism 1 is used to deliver the fluid. Figure 3 and Figure 4 As shown, in some embodiments, the liquid adding device further includes a second driving mechanism 2, which is connected to the liquid adding device 1 and is used to drive the liquid adding mechanism 1 to move along the third direction Z. The second driving mechanism 2 includes a second driving motor 21, a second driving wheel 22 connected to the output end of the driving motor 21, and a second driving belt 23 arranged on the outer periphery of the second driving wheel 22, and the second driving belt 23 extends along the third direction Z and is driven along the third direction Z by the second driving motor 21.
[0043] In some embodiments, the second driving mechanism 2 is connected to the liquid adding mechanism 1 via a second connecting mechanism 3. In some specific application modes, the second connecting mechanism 3 includes a connecting arm 31, a connecting seat 32, a second slide rail 33 and a slider 34, and the second slide rail 33 extends along the third direction Z.
[0044] One end of the connecting arm 31 is connected to the liquid adding mechanism 1 , and the other end of the connecting arm 31 is fixed to the connecting seat 32 . The connecting arm 31 has a gap groove 311 near the connecting seat 32 .
[0045] The connecting seat 32 is mounted on the second slide rail 33 through the slider 34. The connecting seat 32 can slide along the second slide rail 33 driven by the slider 34. The second driving belt 23 is fixed to the connecting seat 32, thereby driving the connecting seat 32 to slide along the third direction Z. The connecting seat 32 has a second connecting groove 321, and the second connecting groove 321 extends along the second direction Y. The connecting arm 31 includes a clamping block, and the clamping block is located in the second connecting groove 321. The second connecting groove 321 extending along the second direction Y cooperates to adjust the installation distance of the liquid adding mechanism 1 in the second direction Y. First, it can be used to offset the assembly tolerance, and second, it can adjust the position of the liquid adding mechanism 1 in accordance with the specific conditions of the cup body 6.
[0046] like Figure 5 and Figure 6 As shown, in order to ensure the stability of the structure, the liquid adding device of the present application also includes a supporting mechanism 5, which includes a first supporting plate 51, and the first supporting plate 51 is arranged at both ends of the second slide rail 33, and the second driving motor 21 and the second driving wheel 22 are also fixed on the first supporting plate 51.
[0047] The second support plate 52 is disposed below the second slide rail 33 and connected to the second slide rail 33 . The second support plate 52 is disposed below the second slide rail 33 to further support the second slide rail 33 and reduce the stability of the liquid adding mechanism 1 when driven by the second driving mechanism 2 .
[0048] The support mechanism 5 of the present application further includes a first support rod 53 , both ends of which are connected to the first support plate 51 , and the first support rod 53 is used to fix the liquid delivery mechanism 4 .
[0049] In some embodiments, the liquid delivery mechanism 4 is included, the liquid delivery mechanism 4 is connected to the liquid adding mechanism 1, the liquid delivery mechanism 4 includes at least one liquid delivery unit 40, the liquid delivery mechanism 4 is used to control the amount of liquid delivered to the liquid adding mechanism 1, specifically, the number of liquid delivery units 40 provided corresponds to the number of needles 12. In some specific application examples, the liquid delivery unit 40 includes a syringe pump drive motor, a solenoid valve and a syringe pump, the solenoid valve is a three-way valve, the syringe pump drive motor is used to control the liquid flow rate delivered by the syringe pump; the solenoid valve is used to control the liquid flow direction in the syringe pump, and the liquid outlet of the syringe pump is connected to the liquid adding needle 12 through the solenoid valve. Figure 7 and Figure 8 As shown, the cup body 6 of the present application includes multiple cup bodies 6, and the multiple cup bodies 6 are arranged below the liquid adding mechanism 1. The liquid nitrogen contained in the cup body 6 of the present application can be used for the preparation and preservation of liquid nitrogen frozen beads of samples.
[0050] Working principle: The liquid adding mechanism 1 of the present application realizes the movement of the liquid adding mechanism 1 in the first direction X through the first driving mechanism 14, and realizes the movement of the liquid adding mechanism 1 in the third direction Z through the second driving mechanism 2, so that the liquid adding needle 12 can move to the top of the four partitions of the filter net of the cup body 6, and the liquid adding amount is controlled by the liquid delivery mechanism 4. For example, in a specific application example, the four liquid adding needles 12 can move to the top of the four partitions of the filter net of two rows of cup bodies 6. The first driving motor 141 drives the first driving wheel 142 to rotate, and the first driving belt 143 is installed on the first driving wheel 142. The first driving belt 143 is connected to the first fixed bracket 11. As the first driving motor 141 rotates, the first fixed bracket 11 moves up and down in the first direction X, so that the four needles 12 can penetrate into the four partitions of the filter net. The syringe pump drive motor mainly drives the syringe pump installed on the pump shaft motion guide rail to move up and down in the first direction X, playing the role of sucking and discharging liquid; the role of the solenoid valve: the solenoid valve is a three-way valve, one of which is connected to the syringe pump, and the other two are normally open and normally closed. When the syringe pump sucks liquid, the solenoid valve works, the normally closed end switches to normally open, and the liquid enters the syringe pump from the container. When the syringe pump discharges liquid, the solenoid valve does not work, and the liquid in the syringe pump will be injected into the needle from the normally open end to complete the dripping process.
[0051] Description of the coordinated movement of the whole machine: When the four needles move to the top of a column of partitions in the two cup bodies 6 (liquid nitrogen cups), the injection pump drive motor rotates, driving the injection pump to move in the positive direction of the first direction X, and the liquid flows into the needle 12 through the solenoid valve switching passage. At the same time, the first drive motor 141 drives the needle to move in the negative direction of the first direction X, and the needle 12 is deeply inserted into the filter screen partition. The liquid is added to the liquid nitrogen in the form of round liquid beads. The round liquid beads will condense into ice beads in the liquid nitrogen and sink to the bottom of the liquid nitrogen cup. The work of this equipment is completed.
Claims
1. A liquid adding mechanism, characterized in that: Comprising a first fixing bracket (11), the first fixing bracket (11) comprising at least one or more fixing units (110), the fixing units (110) extending along a first direction (X), and the fixing units (110) having a receiving cavity (1101) extending along the first direction (X); A liquid adding needle (12), the liquid adding needle (12) being connected to the fixing unit (110), and the liquid adding needle (12) being in communication with the accommodating chamber (1101); A first connecting mechanism (13), the first connecting mechanism (13) being connected to the first fixing bracket (11); A first driving mechanism (14), wherein the first driving mechanism (14) is connected to the first connecting mechanism (13), and the first driving mechanism (14) drives the first connecting mechanism (13) to move along the first direction (X), thereby driving the first fixed bracket (11) and the liquid adding needle (12) to move along the first direction (X).
2. The liquid adding mechanism according to claim 1, characterized in that: The fixing unit (110) has a first mounting hole (1102), and the accommodating cavity (1101) is in communication with the first mounting hole (1102).
3. The liquid adding mechanism according to claim 1, characterized in that: The first driving mechanism (14) comprises a first driving motor (141), a first driving wheel (142) and a first driving belt (143); the first driving belt (143) is connected to the first driving wheel (142), and the first driving motor (141) drives the first driving wheel (142) to rotate, thereby driving the first driving belt (143) to move along the first direction (X).
4. The liquid adding mechanism according to claim 3, characterized in that: The first connection mechanism (13) comprises a first connection block (131), and the first connection block (131) is connected to the first fixing bracket (11); A second connecting block (132), the second connecting block (132) is connected to the first connecting block (131), and the second connecting block (132) has a first connecting groove (1321); the first driving belt (143) passes through the first connecting groove (1321), and the first driving belt (143) is connected to the second connecting block (132).
5. The liquid adding mechanism according to claim 4, characterized in that: The first connecting mechanism (13) comprises a first slide rail (133), the first connecting block (131) is mounted on the first slide rail (133) via a slide groove, and the first slide rail (133) is arranged in parallel with the first driving belt (143).
6. The liquid adding mechanism according to claim 5, characterized in that: The invention comprises a first protection mechanism (15), wherein the first protection mechanism (15) is arranged on the periphery of the first slide rail (133) and the first driving belt (143); and / or the first protection mechanism (15) comprises a first frame (151) and a protection plate (152) arranged on one side of the first frame (151), and the first connecting block (131) passes through a slide groove on the protection plate (152) to be connected to the first slide rail (133).
7. A liquid adding device, characterized in that: It comprises a liquid adding mechanism (1) as claimed in any one of claims 1 to 6, wherein the liquid adding mechanism (1) is used for delivering fluid.
8. The liquid adding device according to claim 7, characterized in that: comprising a second driving mechanism (2), the second driving mechanism (2) being connected to the liquid adding mechanism (1) and being used for driving the liquid adding mechanism (1) to move along a third direction (Z); and / or, The second driving mechanism (2) is connected to the liquid adding mechanism (1) via a second connecting mechanism (3); the second connecting mechanism (3) comprises a connecting arm (31), a connecting seat (32) and a second slide rail (33); the second slide rail (33) extends along a third direction (Z); one end of the connecting arm (31) is connected to the liquid adding mechanism (1), and the other end of the connecting arm (31) is fixed to the connecting seat (32); the connecting seat (32) is mounted on the second slide rail (33), and the connecting seat (32) can slide along the second slide rail (33); and / or, The second driving mechanism (2) comprises a second driving motor (21), a second driving wheel (22) connected to an output end of the driving motor (21), and a second driving belt (23) arranged on the outer periphery of the second driving wheel (22), the second driving belt (23) being fixed to the connecting seat (32); and / or, The connecting seat (32) has a second connecting groove (321), the second connecting groove (321) extends along a second direction (Y), the connecting arm (31) comprises a clamping block, the clamping block is located in the second connecting groove (321); and / or, The connecting arm (31) has a clearance groove (311) near the connecting seat (32); and / or, The connecting seat (32) is connected to the second slide rail (33) via a sliding block (34).
9. The liquid adding device according to claim 8, characterized in that: The liquid delivery mechanism (4) is connected to the liquid adding mechanism (1), the liquid delivery mechanism (4) comprises at least one liquid delivery unit (40), and the liquid delivery mechanism (4) is used to control the amount of liquid delivered to the liquid adding mechanism (1).
10. The liquid adding device according to claim 9, characterized in that: It comprises a support mechanism (5), the support mechanism (5) comprising a first support plate (51), the first support plate (51) being arranged at both ends of the second slide rail (33); a second support plate (52), the second support plate (52) being arranged below the second slide rail (33) and connected to the second slide rail (33); A first support rod (53), wherein both ends of the first support rod (53) are connected to the first support plate (51), and the first support rod (53) is used to fix the liquid delivery mechanism (4).