Stem cell exosome storage device

Abstract

The utility model discloses a stem cell exosome storage device which comprises a heat preservation barrel, a barrel cover and a liquid storage container, the heat preservation barrel is movably connected with the barrel cover, the liquid storage container is annular, an inlet is formed in the top side of the liquid storage container, a sealing cover is movably installed on the inlet, the side wall of the liquid storage container is connected with a liquid outlet, and the liquid outlet is communicated with the liquid storage container. A valve is mounted at the liquid outlet; a plurality of limiting columns are vertically connected to the bottom of an inner cavity of the heat preservation barrel, inner rings of the liquid storage containers are arranged on the limiting columns in a sleeving mode, one limiting column can position the multiple sets of liquid storage containers, the liquid storage containers located on the same limiting column are stacked in the vertical direction, the liquid storage containers are annular, the limiting columns penetrate through the inner rings of the liquid storage containers, and the limiting columns penetrate through the inner rings of the liquid storage containers. The liquid storage containers are arranged in the heat preservation barrel, the limiting function is achieved, the liquid storage containers cannot collide with the inner wall of the heat preservation barrel, the containing space can be reduced by stacking the multiple liquid storage containers, the heat preservation barrel is filled with water at the temperature of 4-8 DEG C, the liquid storage containers are surrounded, the heat preservation effect can be effectively achieved, and the temperature is evenly controlled.

Description

Technical Field

[0001] The utility model relates to the field of biotechnology, and in particular to a stem cell exosome storage device. Background Art

[0002] Stem cell exosomes are a type of extracellular vesicles with a complete membrane structure secreted by stem cells, containing a variety of lipids, proteins, RNA and other bioactive factors, with a diameter of about 30 to 150 nm. Stem cell exosomes have similar biological properties to stem cells, but compared with stem cells, exosomes have lower immunogenicity, are safer, more stable and efficient, and have great development and application potential in the fields of modern biology and medicine.

[0003] At present, the storage environment of stem cell exosomes is generally 4-8 degrees Celsius. There are certain limitations on the storage space and environment of multiple groups of stem cell exosome culture fluids. The existing storage containers have a small storage space, cannot provide good protection for the storage containers, and do not consider the optimization of storage space. Utility Model Content

[0004] In order to solve the technical problems existing in the background technology, the utility model proposes a stem cell exosome storage device.

[0005] The utility model provides a stem cell exosome storage device, comprising a heat preservation barrel and a barrel cover, wherein the heat preservation barrel is movably connected to the barrel cover, and further comprising a liquid storage container, wherein the liquid storage container is annular, an inlet is arranged on the top side of the liquid storage container, a sealing cover is movably installed on the inlet, a liquid outlet is connected to the side wall of the liquid storage container, and a valve is installed at the liquid outlet;

[0006] A plurality of limit columns are vertically connected to the bottom of the inner cavity of the heat preservation barrel, and the inner ring of the liquid storage container is sleeved on the limit columns. One limit column can position multiple groups of liquid storage containers, and the liquid storage containers located on the same limit column are stacked in the vertical direction.

[0007] Preferably, an air supply pipe is opened in the inner cavity of the limiting column, and a plurality of groups of annular air bags are installed on the outer wall of the limiting column. The plurality of groups of annular air bags are vertically distributed on the limiting column and correspond one to one with the stacked liquid storage containers. A plurality of connecting pipes are connected between the air supply pipe and each annular air bag, and an air pump is fixedly installed at the bottom of the insulation barrel for supplying air into the air supply pipe.

[0008] Preferably, the outer side wall of the annular airbag is provided with a groove for clamping the inner ring of the liquid storage container.

[0009] Preferably, three limit columns are provided and distributed around the axis center of the heat preservation barrel.

[0010] Preferably, a protective pad is connected to the bottom of each group of liquid storage containers.

[0011] Preferably, the protection pad is made of rubber.

[0012] Preferably, a water outlet pipe is provided on the bottom side wall of the heat preservation barrel, and a control valve is provided on the water outlet pipe.

[0013] Preferably, a supporting foot is fixedly connected to the bottom of the heat preservation barrel.

[0014] In the utility model, a stem cell exosome storage device is proposed, in which stem cell exosome culture fluid in a liquid storage container is introduced into the liquid storage container. The liquid storage container is annular, and a limiting column passes through the inner circle of the emulsion container to play a limiting function, and will not collide with the inner wall of the insulation barrel. Multiple liquid storage containers can be stacked to reduce the storage space. After adding water of suitable temperature into the insulation barrel, the barrel cover support feet are covered; the function of heat preservation storage can be achieved, and the air pump supplies air to each annular airbag through the air supply pipe and each connecting pipe. The airbag is propped up and becomes larger, and the liquid storage container can be fixed from the inner circle of the liquid storage container to avoid a gap between the limiting column and the liquid storage container, thereby avoiding shaking. When the liquid storage container needs to be removed, the air pump pumps air, and the annular airbag contracts, so that the liquid storage container can be removed from the limiting column. The stem cell exosome culture fluid inside each liquid storage container is exported from the liquid outlet. The thermos bucket is filled with 4-8 degrees Celsius water to surround the liquid storage container, which can effectively achieve the effect of heat preservation, uniform temperature control, and positioning protection.

[0015] Additional aspects and advantages of the present invention will be given in part in the following description, and in part will become apparent from the following description, or will be learned through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a front cross-sectional view of the utility model;

[0017] Figure 2 It is a structural schematic diagram of the utility model;

[0018] Figure 3 It is a structural schematic diagram of the liquid storage container in the utility model;

[0019] Figure 4 It is a top view of the liquid storage container in the utility model;

[0020] Figure 5 It is a schematic diagram of the structure of the annular airbag in the utility model when it is not inflated;

[0021] Figure 6 It is a structural schematic diagram of the annular airbag in the utility model when it is inflated.

[0022] Explanation of the numbers in the figure: 1. Insulated barrel; 101. Water outlet pipe; 102. Support foot; 2. Barrel cover; 3. Limiting column; 4. Liquid storage container; 401. Sealing cover; 402. Liquid outlet; 403. Protective pad;

[0023] 5. Air pipe; 6. Annular air bag; 7. Air pump; 8. Connecting pipe. DETAILED DESCRIPTION

[0024] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar symbols throughout represent the same or similar elements or elements with the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0025] like Figure 1-Figure 6 A stem cell exosome storage device shown includes a heat preservation barrel 1 and a barrel cover 2, wherein the heat preservation barrel 1 is movably connected to the barrel cover 2, and the heat preservation barrel 1 is made of stainless steel and has double-layer vacuum insulation.

[0026] It also includes a liquid storage container 4, which is annular, with an inlet on the top side of the liquid storage container 4, a sealing cover 401 movably installed on the inlet, and a liquid outlet 402 connected to the side wall of the liquid storage container 4, and a valve installed at the liquid outlet 402;

[0027] A plurality of limit columns 3 are vertically connected to the bottom of the inner cavity of the heat preservation barrel 1, and the inner ring of the liquid storage container 4 is sleeved on the limit columns 3. One limit column 3 can position multiple groups of liquid storage containers 4, and the liquid storage containers 4 located on the same limit column are stacked in the vertical direction.

[0028] like Figure 1 As shown, the stem cell exosome culture fluid is introduced into the liquid storage container 4 through the liquid storage container 4. The liquid storage container 4 is annular. The limiting column 3 passes through the inner circle of the emulsion container to play a limiting function and will not collide with the inner wall of the thermal insulation barrel 1. Multiple liquid storage containers 4 can be stacked to reduce the storage space. After adding water of suitable temperature into the thermal insulation barrel 1, the barrel cover 2 is covered to achieve the function of thermal insulation storage.

[0029] Preferably, an air supply pipe 5 is opened in the inner cavity of the limiting column 3, and a plurality of groups of annular air bags 6 are installed on the outer wall of the limiting column 3. The plurality of groups of annular air bags 6 are vertically distributed on the limiting column 3, corresponding one to one with the stacked liquid storage containers 4. A plurality of connecting pipes 8 are connected between the air supply pipe 5 and each annular air bag 6. An air pump 7 is fixedly installed at the bottom of the insulation barrel 1 for supplying air to the air supply pipe 5.

[0030] The air pump 7 supplies air to each annular airbag 6 through the air supply pipe 5 and each connecting pipe 8. The airbag is inflated and becomes larger, and the liquid storage container 4 can be fixed from the inner circle of the liquid storage container 4 to avoid a gap between the limit column 3 and the liquid storage container 4, thereby preventing shaking. When the liquid storage container 4 needs to be removed, the air pump 7 draws air, the annular airbag 6 contracts, and the liquid storage container 4 can be removed from the limit column 3.

[0031] The stem cell exosome culture fluid inside each liquid storage container 4 is discharged from the liquid outlet 402 .

[0032] The heat preservation barrel 1 is filled with water at 4-8 degrees Celsius, which surrounds the liquid storage container 4, and can effectively achieve the effect of heat preservation and uniform temperature control.

[0033] Preferably, the outer side wall of the annular airbag 6 is provided with a groove for clamping the inner ring of the liquid storage container 4, so as to cooperate with the inner ring side wall of the liquid storage container 4 to enhance the positioning effect.

[0034] Preferably, three limiting columns 3 are provided and distributed around the axis center of the heat preservation barrel 1 , so that more liquid storage containers 4 can be stored in the heat preservation barrel 1 .

[0035] Preferably, the bottom of each group of liquid storage containers 4 is connected to a protective pad 403, which can raise the bottom of the liquid storage container 4 and create a gap between two adjacent liquid storage containers 4 in the vertical direction, so that water can flow through and ensure the heat preservation effect of the liquid storage container 4.

[0036] Preferably, the protection pad 403 is made of rubber material, and plays a protective role between the stacked liquid storage containers 4.

[0037] Preferably, a water outlet pipe 101 is provided on the bottom side wall of the heat preservation barrel 1 , and a control valve is provided on the water outlet pipe 101 , which can drain the water in the inner cavity of the heat preservation barrel 1 .

[0038] Preferably, a support foot 102 is fixedly connected to the bottom of the heat preservation barrel 1 to ensure the stability of the support.

[0039] It should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0040] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present utility model, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0041] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral one; it can be a mechanical connection, an electrical connection, or communication with each other; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0042] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0043] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A stem cell exosome storage device, comprising a heat preservation barrel (1) and a barrel cover (2), wherein the heat preservation barrel (1) and the barrel cover (2) are movably connected, and characterized in that: It also comprises a liquid storage container (4), the liquid storage container (4) is annular, an inlet is arranged on the top side of the liquid storage container (4), a sealing cover (401) is movably mounted on the inlet, a liquid outlet (402) is connected to the side wall of the liquid storage container (4), and a valve is mounted at the outlet of the liquid outlet (402); A plurality of limit columns (3) are vertically connected to the bottom of the inner cavity of the heat preservation barrel (1); the inner ring of the liquid storage container (4) is sleeved on the limit columns (3); one limit column (3) can position multiple groups of liquid storage containers (4); and the liquid storage containers (4) located on the same limit column are stacked in the vertical direction.

2. A stem cell exosome storage device according to claim 1, characterized in that: An air delivery pipe (5) is provided in the inner cavity of the limiting column (3), and a plurality of groups of annular air bags (6) are installed on the outer wall of the limiting column (3). The plurality of groups of annular air bags (6) are vertically distributed on the limiting column (3) and correspond one to one with the stacked liquid storage containers (4). A plurality of connecting pipes (8) are connected between the air delivery pipe (5) and each annular air bag (6). An air pump (7) is fixedly installed at the bottom of the heat preservation barrel (1) for supplying air into the air delivery pipe (5).

3. A stem cell exosome storage device according to claim 2, characterized in that: The outer side wall of the annular airbag (6) is provided with a groove for clamping the inner ring of the liquid storage container (4).

4. A stem cell exosome storage device according to claim 1, characterized in that: The limiting columns (3) are provided with three pieces and are distributed around the axis center of the heat preservation barrel (1).

5. A stem cell exosome storage device according to claim 1, characterized in that: The bottom of each group of liquid storage containers (4) is connected to a protective pad (403).

6. A stem cell exosome storage device according to claim 5, characterized in that: The protection pad (403) is made of rubber.

7. A stem cell exosome storage device according to claim 1, characterized in that: A water outlet pipe (101) is provided on the bottom side wall of the heat preservation barrel (1), and a control valve is provided on the water outlet pipe (101).

8. The stem cell exosome storage device according to claim 1, characterized in that: The bottom of the heat preservation barrel (1) is fixedly connected with a supporting foot (102).

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