Membrane type liquid-based thin-layer cell slide preparation mechanism
By designing integrated components and separation components in the cell production mechanism, the problem of inefficient manual operation of the barrier cartridge in the prior art is solved, and the barrier cartridge is quickly placed and removed, and the production efficiency is improved.
Patent Information
- Application Number
- CN202420355700.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-02-26
- Publication Date
- 2025-03-07
- Estimated Expiration
- 2034-02-26
AI Technical Summary
The existing cell filmmakers need to manually operate the stopper before and after the production, which is inefficient and takes a lot of time.
A membrane liquid-based thin-layer cell tableting mechanism is designed, including an integration assembly and a separation assembly. By quickly placing and removing the stop cylinder through the integration assembly, the separation assembly cooperates with the machine head to quickly lift the integration disc, and remove the stop cylinder from the surface of the slide.
It realizes the rapid placement and removal of a large number of stoppers during cell production, significantly reducing the time of manual operation and improving production efficiency.
Smart Images

Figure CN222579742U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of cell slice making, in particular to a membrane type liquid-based thin layer cell slice making mechanism. Background Art
[0002] According to the principle of liquid-based cytology, pneumatic and hydraulic principles are used to disperse, filter, collect and transfer the collected cell samples. The rotating mechanism drives the filter membrane cylinder to gently mix the cell samples; the computer-controlled pneumatic and fluid power system is used for the entire process of cell collection; using biochemical principles, the cells collected on the filter membrane are naturally adsorbed to the glass slide, achieving the purpose of perfect cell transfer and uniform single-layer paving, which is convenient for staining and diagnosis;
[0003] The existing slide making machine needs to place the retaining tube on the top of the slide before making the slide, and the two are sucked together, which is often done manually one by one, which takes a lot of time. At the same time, after the slide is stained, the retaining tube is also manually removed one by one, which is relatively inefficient.
[0004] Therefore, we propose a membrane-type liquid-based thin layer cell preparation mechanism. Utility Model Content
[0005] The utility model aims to provide a membrane-type liquid-based thin layer cell preparation mechanism to solve the problems raised in the above-mentioned background technology.
[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a membrane-type liquid-based thin-layer cell preparation mechanism, comprising a machine base, the upper end outer surface of the machine base is movably connected to a machine head, the lower end outer surface of the machine head is fixedly connected to a sampling rod, the upper end outer surface of the machine base is connected to a turntable through a motor rotation, the upper end of the turntable is fixedly connected to a glass slide through a suction cup, and a retaining cylinder is placed on the glass slide;
[0007] An integration component, which is located above the turntable and centrally separates the baffles placed on the surface of the turntable;
[0008] A separation component is located inside the turntable and at the lower end of the integration component, and separates the integration component from the turntable;
[0009] Among them, the integration component includes an integration disk, a card block is fixedly connected to the lower end of the integration disk, a card slot is opened at the upper end of the turntable, the card block is located inside the card slot, a socket is opened on the outer surface of the integration disk ring, the blocking cylinder is inserted into the socket, and the lower end of the blocking cylinder is in contact with the glass slide.
[0010] Among them, a retaining ring is fixedly connected to the annular outer surface of the retaining cylinder, a retaining groove is opened on the annular inner surface of the socket, the retaining groove and the retaining ring correspond to each other, and a blocking block is fixedly connected to the inner surface of the retaining groove.
[0011] Among them, a liquid storage cavity is provided on the outer surface of the upper end of the integration disk, and a transmission groove is provided on the inner surface of the liquid storage cavity. The end of the transmission groove away from the liquid storage cavity is connected to the socket, and a pushing block is slidably connected inside the transmission groove. The end of the pushing block contacts the outer surface of the retaining cylinder, and a lower pressure plate is slidably connected inside the liquid storage cavity. A spring is fixedly connected between the lower pressure plate and the liquid storage cavity.
[0012] Among them, the separation component includes a separation groove, a separation rod is slidably connected inside the separation groove, a telescopic groove is opened at the center position of the separation rod, a force-bearing rod is slidably connected inside the telescopic groove, a through groove is opened at the corresponding positions of the integration disk and the force-bearing disk, the force-bearing rod passes through the through groove, and a spring 2 is fixedly connected to the outer surface of the lower end of the force-bearing rod.
[0013] Wherein, a guide block is fixedly connected to the annular outer surface of the separation rod, and a guide groove is provided inside the separation groove at a position corresponding to the guide block.
[0014] Wherein, a handle is fixedly connected to the outer surface of the upper end of the integration plate, and the handle is designed as a segmented structure.
[0015] The utility model has at least the following beneficial effects:
[0016] By setting up an integrated component, the user can quickly place a large number of retaining tubes on the surface of the glass slide when making cell slides, and they can also be quickly removed from the surface of the glass slide at the same time, reducing the time spent on removing the retaining tubes one by one and increasing the production efficiency. By setting up a separation component, the integrated disk can be quickly lifted up in cooperation with the machine head to separate the retaining tube from the surface of the glass slide. The structure is simple and fast, and only needs to be removed manually. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;
[0018] Figure 2 It is a structural schematic diagram of the turntable and the integrated disk of the utility model;
[0019] Figure 3 This is a schematic diagram of the cutaway structure of the integrated disk of the utility model;
[0020] Figure 4 For this utility model Figure 3 The enlarged structural diagram at A in the middle;
[0021] Figure 5 It is a side view structural diagram of the turntable and the integrated disk of the utility model;
[0022] Figure 6 It is a schematic diagram of the structure of the integrated disk of the utility model in a transverse section;
[0023] Figure 7 For this utility model Figure 6 Enlarged structural diagram at B in the middle.
[0024] In the figure: 1. base; 11. machine head; 12. sampling rod; 13. turntable; 14. retaining cylinder; 15. retaining ring; 2. integration component; 20. integration disk; 201. card block; 202. card slot; 21. socket; 22. retaining slot; 23. blocking block; 24. handle; 25. through slot; 26. lower pressure plate; 27. liquid storage chamber; 28. transmission slot; 281. push block; 29. spring one; 3. separation component; 30. separation slot; 31. separation rod; 32. force rod; 33. telescopic slot; 34. guide slot; 35. guide block; 36. spring two. DETAILED DESCRIPTION
[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0026] See also Figure 1-7 The utility model provides a technical solution: a membrane-type liquid-based thin-layer cell preparation mechanism, comprising a machine base 1, a machine head 11 is movably connected to the outer surface of the upper end of the machine base 1, a sampling rod 12 is fixedly connected to the outer surface of the lower end of the machine head 11, a turntable 13 is connected to the outer surface of the upper end of the machine base 1 through a motor rotation, a glass slide (existing technology) is fixedly connected to the upper end of the turntable 13 through a suction cup, and a retaining cylinder 14 is placed on the glass slide, the sample is sucked by the machine head 11 and then dripped into the retaining cylinder 14, so that the sample is fully in contact with the surface of the glass slide, and then the turntable 13 rotates to throw the sample liquid out of the retaining cylinder 14 through centrifugal force, the sample on the surface of the glass slide is discharged, and then a staining liquid is dripped to stain the glass slide;
[0027] An integration component 2 is located above the turntable 13, and the baffles 14 placed on the surface of the turntable 13 are centrally separated. After dyeing, all the baffles 14 can be directly removed by the integration component 2, and no longer need to be removed one by one, thus saving time;
[0028] The separation component 3 is located inside the turntable 13 and at the lower end of the integration component 2, and is used to separate the integration component 2 and the turntable 13. The separation component 3 cooperates with the head 11 to quickly separate the retaining cylinder 14 sucked on the glass slide from the glass slide, so that the user can remove the glass slide easily.
[0029] The integration component 2 includes an integration disk 20, a card block is fixedly connected to the lower end of the integration disk 20, a card slot is opened at the upper end of the turntable 13, the card block is located inside the card slot, a socket 21 is opened on the outer surface of the ring of the integration disk 20, the blocking cylinder 14 is inserted inside the socket 21, and the lower end of the blocking cylinder 14 is in contact with the glass slide. Before use, the user inserts the blocking cylinders 14 into the socket 21 one by one, and then aligns the card block with the card slot and lowers it, and then the head 11 controls the sampling rod 12 to press the integration disk 20. While pressing, the turntable 13 rotates, so that the head 11 can better stick the blocking cylinder 14 to the surface of the glass slide (at this time, the sampling rod 12 has not inserted the sampling tube).
[0030] A retaining ring 15 is fixedly connected to the annular outer surface of the retaining cylinder 14, and a retaining groove 22 is formed on the annular inner surface of the socket 21. The retaining groove 22 corresponds to and matches the retaining ring 15, and a blocking block 23 is fixedly connected to the inner surface of the retaining groove 22. Through the design of the retaining ring 15 and the retaining groove 22, the downward pressure of the sampling rod 12 can be better transmitted to the surface of the glass slide, and the blocking block 23 can increase the stability of the retaining ring 15 inside the retaining groove 22.
[0031] The outer surface of the upper end of the integrated disk 20 is provided with a liquid storage chamber 27, and the inner surface of the liquid storage chamber 27 is provided with a transmission groove 28. The end of the transmission groove 28 away from the liquid storage chamber 27 is connected to the socket 21, and a pushing block 281 is slidably connected inside the transmission groove 28, and the end of the pushing block 281 contacts the outer surface of the blocking cylinder 14. A lower pressure plate 26 is slidably connected inside the liquid storage chamber 27, and a spring 29 is fixedly connected between the lower pressure plate 26 and the liquid storage chamber 27. If it is necessary to completely remove the blocking cylinder 14 inside the socket 21, the lower pressure plate 26 is directly pressed, and the lower pressure plate 26 moves downward inside the liquid storage chamber 27 and compresses the spring 29. At this time, the liquid inside the liquid storage chamber 27 flows to the pushing block 281 through the transmission groove 28, and the pushing block 281 is aligned with the blocking cylinder 14 to push the blocking cylinder 14 out of the socket 21, thereby completing the overall removal of the blocking cylinder 14 and saving removal time.
[0032] The separation component 3 includes a separation groove 30, wherein a separation rod 31 is slidably connected to the separation groove 30, a telescopic groove 33 is provided at the center position of the separation rod 31, and a force-bearing rod 32 is slidably connected to the telescopic groove 33. A through groove 25 is provided at the corresponding position of the integration disk 20 and the force-bearing disk, and the force-bearing rod 32 passes through the through groove 25. A spring 26 is fixedly connected to the outer surface of the lower end of the force-bearing rod 32. When the glass slide is stained and the retaining cylinder 14 needs to be removed from the glass slide surface, the sampling rod 12 is driven by the machine head 11 to move above the force-bearing rod 32, and then the force-bearing rod 32 is pressed downward. The force-bearing rod 32 moves downward in the separation groove 30 and compresses the spring 26. At this time, liquid is injected into the separation groove 30, and the downward movement of the force-bearing rod 32 reduces the space inside the separation groove 30. The liquid pushes the separation rod 31 to move upward along the separation groove 30, resists the integration disk 20 and lifts up the integration disk 20, so that the retaining cylinder 14 is separated from the glass slide.
[0033] A guide block 35 is fixedly connected to the annular outer surface of the separation rod 31 , and a guide groove 34 is provided inside the separation groove 30 at a position corresponding to the guide block 35 , so as to increase the stability of the movement of the separation rod 31 inside the separation groove 30 .
[0034] A handle 24 is fixedly connected to the outer surface of the upper end of the integrated disk 20. After the separation component 3 separates the integrated disk 20 from the turntable 13, the user can remove the integrated disk 20 through the handle 24, and at the same time hold the handle 24 and push the lower pressure plate 26 with the knuckles to facilitate the user to remove the retaining cylinder 14, aim at the trash can, and then hold the handle 24 to throw the used retaining cylinder 14 into the trash can. The handle 24 is designed as a segmented structure, which is convenient for the sampling rod 12 to squeeze the force-bearing rod 32.
[0035] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.
[0036] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A membrane-type liquid-based thin-layer cell preparation mechanism, comprising a machine base (1), the upper outer surface of the machine base (1) is movably connected to a head (11), the lower outer surface of the head (11) is fixedly connected to a sampling rod (12), the upper outer surface of the machine base (1) is rotatably connected to a turntable (13) via a motor, the upper end of the turntable (13) is fixedly connected to a glass slide via a suction cup, and a retaining cylinder (14) is placed on the glass slide; Features: An integration component (2), the integration component (2) is located above the turntable (13) and performs centralized separation on the retaining cylinder (14) placed on the surface of the turntable (13); A separation component (3) is located inside the rotating disk (13) and at the lower end of the integration component (2) to separate the integration component (2) and the rotating disk (13).
2. The membrane-type liquid-based thin layer cell preparation mechanism according to claim 1, characterized in that: The integration component (2) comprises an integration disk (20), a clamping block is fixedly connected to the lower end of the integration disk (20), a clamping slot is provided at the upper end of the rotating disk (13), the clamping block is located inside the clamping slot, a socket (21) is provided on the outer surface of the ring of the integration disk (20), the retaining tube (14) is inserted into the socket (21), and the lower end of the retaining tube (14) is in contact with the glass slide.
3. The membrane-type liquid-based thin layer cell preparation mechanism according to claim 2, characterized in that: The annular outer surface of the retaining cylinder (14) is fixedly connected to a retaining ring (15), the annular inner surface of the socket (21) is provided with a retaining groove (22), the retaining groove (22) and the retaining ring (15) correspond to each other, and the inner surface of the retaining groove (22) is fixedly connected to a blocking block (23).
4. The membrane-type liquid-based thin layer cell preparation mechanism according to claim 3, characterized in that: The outer surface of the upper end of the integration disk (20) is provided with a liquid storage cavity (27), and the inner surface of the liquid storage cavity (27) is provided with a transmission groove (28). The end of the transmission groove (28) away from the liquid storage cavity (27) is connected to the socket (21), and a pushing block (281) is slidably connected inside the transmission groove (28). The end of the pushing block (281) contacts the outer surface of the retaining cylinder (14). A lower pressure plate (26) is slidably connected inside the liquid storage cavity (27), and a spring (29) is fixedly connected between the lower pressure plate (26) and the liquid storage cavity (27).
5. The membrane-type liquid-based thin layer cell preparation mechanism according to claim 2, characterized in that: The separation component (3) comprises a separation groove (30), a separation rod (31) is slidably connected inside the separation groove (30), a telescopic groove (33) is provided at the center position of the separation rod (31), a force-bearing rod (32) is slidably connected inside the telescopic groove (33), a through groove (25) is provided at the corresponding position of the integration disk (20) and the force-bearing disk, the force-bearing rod (32) passes through the through groove (25), and a spring 2 (36) is fixedly connected to the outer surface of the lower end of the force-bearing rod (32).
6. The membrane-type liquid-based thin layer cell preparation mechanism according to claim 5, characterized in that: A guide block (35) is fixedly connected to the annular outer surface of the separation rod (31), and a guide groove (34) is provided inside the separation groove (30) at a position corresponding to the guide block (35).
7. The membrane-type liquid-based thin layer cell preparation mechanism according to claim 4, characterized in that: A handle (24) is fixedly connected to the outer surface of the upper end of the integration plate (20), and the handle (24) is designed as a segmented structure.