Filter membrane press-in type plasma rapid separation TIP head

Abstract

The utility model relates to a filter membrane press-in type plasma rapid separation TIP head which comprises a shell and a filter membrane, a liquid inlet is formed in the lower bottom end of the shell, and the filter membrane covers the liquid inlet to be used for separating red blood cells and plasma. Compared with the prior art, the filter membrane press-in type plasma rapid separation TIP head is provided with the filter membrane, when the TIP head is inserted into a whole blood microcup to suck whole blood in the whole blood microcup, the whole blood is reversely pressed into the TIP head through the liquid inlet through the downward pressing action, when the whole blood penetrates through the filter membrane, red blood cells are blocked and left in the whole blood microcup, and the whole blood is separated from the whole blood microcup. Plasma can penetrate through the filter membrane to enter the TIP head; the TIP head can be used for separating red blood cells from blood plasma, so that the blood treatment efficiency is improved, and the blood detection speed is increased.

Description

Technical Field

[0001] The utility model relates to the technical field of blood detection, in particular to a filter membrane press-in type plasma rapid separation TIP head. Background Art

[0002] The TIP head is a pipette tip or pipette tip used on automated or semi-automated pipetting equipment, which can store and dispense solutions. The TIP head is a pipette tip or pipette tip used on automated or semi-automated pipetting equipment, which can store and dispense solutions. It is a disposable consumable. In the experimental research process of molecular biology and genetics, it can effectively form a protective structure between the pipette and the sample, ensuring the safety of sampling and splitting.

[0003] The existing TIP head only has the function of pipetting. Blood is generally separated by using a centrifuge, which takes 6 to 15 minutes for each separation and is inefficient. Utility Model Content

[0004] In view of this, it is necessary to provide a membrane-pressed plasma rapid separation TIP head to solve the technical problem that the TIP in the prior art does not have the function of separating blood.

[0005] The utility model provides a membrane press-in type plasma rapid separation TIP head, which comprises a shell and a filter membrane. A liquid inlet is formed at the lower end of the shell, and the filter membrane covers the liquid inlet to separate red blood cells and plasma.

[0006] Furthermore, an exhaust port is formed on the upper portion of the shell.

[0007] Furthermore, the shell includes an outer shell and a supporting part, the liquid inlet is located at the lower bottom end of the outer shell, the supporting part is built into the outer shell and fixedly connected to the outer shell, the lower end of the supporting part also abuts against the filter membrane, and a channel for plasma to pass is formed between the supporting part and the outer shell.

[0008] Furthermore, the cross section of the support portion is cross-shaped.

[0009] Furthermore, the shell also includes an upper cavity and a lower cavity, the lower end of the upper cavity is fixedly connected to the upper end of the lower cavity, the upper end of the support part is also fixedly connected to the upper cavity, and the liquid inlet is located at the lower bottom end of the lower cavity.

[0010] Furthermore, ultrasonic welding is used between the upper cavity and the lower cavity.

[0011] Furthermore, the lower cavity is an inverted frustum structure with a larger upper portion and a smaller lower portion.

[0012] Furthermore, the side surface of the support portion is correspondingly fitted with the inner wall of the lower cavity.

[0013] Furthermore, the filter membrane has honeycomb-shaped filter holes, and the pore size of the filter holes is 4.5-5.5 microns.

[0014] Furthermore, the filter membrane push-in type plasma rapid separation TIP head includes a plurality of stacked filter membranes.

[0015] Compared with the prior art, the filter membrane press-in type plasma rapid separation TIP head provided by the utility model has a filter membrane. When the TIP head is inserted into a whole blood micro cup to absorb the whole blood therein, the downward pressing action reversely presses the whole blood into the TIP head through the liquid inlet. When the whole blood passes through the filter membrane, the red blood cells are blocked and remain in the whole blood micro cup, and the plasma can pass through the filter membrane and enter the TIP head; the TIP head can separate red blood cells and plasma, speed up the blood processing efficiency, and improve the blood detection speed.

[0016] The above description is only an overview of the technical solution of the utility model. In order to more clearly understand the technical means of the utility model and implement it according to the contents of the specification, the preferred embodiment of the utility model is described in detail as follows with the accompanying drawings. The specific implementation method of the utility model is given in detail by the following embodiments and their drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The drawings described herein are used to provide a further understanding of the present invention and constitute a part of the present application. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation on the present invention. In the drawings:

[0018] Figure 1 A schematic structural diagram of an embodiment of a membrane press-in plasma rapid separation TIP head provided by the utility model;

[0019] Figure 2 A schematic diagram of the structure of the membrane press-in type plasma rapid separation TIP head provided by the utility model when in use;

[0020] Figure 3 for Figure 2 Exploded diagram of

[0021] Figure 4 for Figure 2 sectional view of . DETAILED DESCRIPTION

[0022] The preferred embodiments of the present invention are described in detail below in conjunction with the accompanying drawings, wherein the accompanying drawings constitute a part of the present application and are used together with the embodiments of the present invention to illustrate the principles of the present invention, but are not used to limit the scope of the present invention.

[0023] See also Figures 1 to 4The utility model provides a membrane press-in type plasma rapid separation TIP head. The membrane press-in type plasma rapid separation TIP head comprises a housing 1 and a filter membrane 2. A liquid inlet is formed at the lower end of the housing 1. The filter membrane 2 covers the liquid inlet to separate red blood cells and plasma.

[0024] When the TIP head is inserted into the whole blood micro-cup 5 to absorb the whole blood therein, the downward pressing action reversely presses the whole blood into the TIP head through the liquid inlet. When the whole blood passes through the filter membrane 2, the red blood cells are blocked and remain in the whole blood micro-cup 5, and the plasma can pass through the filter membrane 2 and enter the TIP head. The TIP head is used to separate the red blood cells and plasma while absorbing the whole blood, and there is no need to separate the red blood cells and plasma separately, which speeds up the blood processing efficiency and improves the blood detection speed.

[0025] In some embodiments, an exhaust port 101 is also formed on the upper portion of the housing 1 for exhausting air when separating whole blood, so as to facilitate the entry of plasma into the housing 1 .

[0026] In some embodiments, the housing 1 includes an outer shell 11 and a support portion 12, the liquid inlet is located at the lower end of the outer shell 11, the support portion 12 is built into the outer shell 11 and fixedly connected to the outer shell 11, the lower end of the support portion 12 is also in contact with the filter membrane 2, and a channel for plasma to pass is formed between the support portion 12 and the outer shell 11. When separating whole blood, the pressure will cause the filter membrane 2 to bulge upward, and the support portion 12 limits the bulge of the filter membrane 2 to avoid damage to the filter membrane due to excessive pressure.

[0027] In some embodiments, the housing 11 further includes an upper cavity 111 and a lower cavity 112, the lower end of the upper cavity 111 and the upper end of the lower cavity 112 are fixedly connected, the upper end of the support portion 12 is also fixedly connected to the upper cavity 111, and the liquid inlet is located at the lower bottom end of the lower cavity 112. Ultrasonic welding is preferably used between the upper cavity 111 and the lower cavity 112. The support portion 12 and the upper cavity 111 can be connected by interference fit, and the upper end of the support portion 12 is inserted into the upper cavity 111 to form a fixed structure. Other fixed connection methods can also be used, such as gluing or ultrasonic welding.

[0028] In order to adapt to the whole blood micro-cup 5 , the lower cavity 112 preferably adopts an inverted frustum structure with a larger upper part and a smaller lower part, and the size can just be inserted into the whole blood micro-cup 5 .

[0029] In the corresponding embodiment, the side surface of the support portion 12 is correspondingly fitted with the inner wall of the lower cavity. The cross section of the support portion 12 is preferably in the shape of a cross, and the gaps between the crosses serve as channels for blood circulation.

[0030] In some embodiments, the filter membrane 2 has honeycomb filter holes with a pore size of 4.5-5.5 microns. This size can block red blood cells but allow plasma to pass through at a faster rate. In actual use, several filter membranes 2 can be stacked as needed to obtain a better filtering effect.

[0031] Compared with the prior art, the filter membrane press-in type plasma rapid separation TIP head provided by the utility model has a filter membrane. When the TIP head is inserted into a whole blood micro cup to absorb the whole blood therein, the downward pressing action reversely presses the whole blood into the TIP head through the liquid inlet. When the whole blood passes through the filter membrane, the red blood cells are blocked and remain in the whole blood micro cup, and the plasma can pass through the filter membrane and enter the TIP head; the TIP head can separate red blood cells and plasma, speed up the blood processing efficiency, and improve the blood detection speed.

[0032] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any changes or substitutions that can be easily thought of by any technician familiar with the technical field within the technical scope disclosed in the present invention should be included in the protection scope of the present invention.

Claims

1. A membrane press-in plasma rapid separation TIP head, characterized in that: It includes: A shell and a filter membrane, wherein a liquid inlet is formed at the lower bottom of the shell, and the filter membrane covers the liquid inlet to separate red blood cells and plasma.

2. The membrane press-in plasma rapid separation TIP head according to claim 1, characterized in that: An exhaust port is also formed on the upper portion of the shell.

3. The membrane press-in plasma rapid separation TIP head according to claim 1, characterized in that: The shell includes an outer shell and a supporting portion, the liquid inlet is located at the lower bottom end of the outer shell, the supporting portion is built into the outer shell and fixedly connected to the outer shell, the lower end of the supporting portion is also in contact with the filter membrane, and a channel for plasma to pass through is formed between the supporting portion and the outer shell.

4. The membrane press-in plasma rapid separation TIP head according to claim 3, characterized in that: The cross section of the supporting portion is cross-shaped.

5. The membrane press-in plasma rapid separation TIP head according to claim 3, characterized in that: The shell also includes an upper cavity and a lower cavity, the lower end of the upper cavity is fixedly connected to the upper end of the lower cavity, the upper end of the support portion is also fixedly connected to the upper cavity, and the liquid inlet is located at the lower bottom end of the lower cavity.

6. The membrane press-in plasma rapid separation TIP head according to claim 5, characterized in that: Ultrasonic welding is adopted between the upper cavity and the lower cavity.

7. The membrane press-in plasma rapid separation TIP head according to claim 5, characterized in that: The lower cavity is an inverted truncated cone structure with a larger upper portion and a smaller lower portion.

8. The membrane press-in plasma rapid separation TIP head according to claim 7, characterized in that: The side surface of the supporting portion is correspondingly fitted with the inner wall of the lower cavity.

9. The membrane press-in plasma rapid separation TIP head according to claim 1, characterized in that: The filter membrane has honeycomb-shaped filtering holes, and the pore size of the filtering holes is 4.5-5.5 microns.

10. The membrane press-in plasma rapid separation TIP head according to claim 1, characterized in that: The filter membrane push-in type plasma rapid separation TIP head comprises a plurality of stacked filter membranes.

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