Safe storage device for antibody

By designing buffer components and partition components in the antibody storage device, the problem of changes in the protein structure of the antibody sample caused by the vibration of the storage box is solved, and higher storage stability and practicality are achieved.

CN222592199UActive Publication Date: 2025-03-11SUZHOU RUI YING BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420747651.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-11
Publication Date
2025-03-11
Estimated Expiration
2034-04-11

AI Technical Summary

Technical Problem

During the movement of existing antibody storage devices, the antibody sample in the storage box will vibrate, which may cause changes in the protein structure, affecting its ability to bind to the target protein, and reducing the practicality of the storage device.

Method used

A safe storage device for antibodies is designed, including a base, storage box, buffer assembly and partition assembly. The buffer assembly uses the rotation and sliding of the movable plate and the moving block through the connecting shaft, movable plate, movable block, slider and spring structure, and combines the double buffering of the second spring and the damper to reduce the vibration of the storage box. The partition assembly uses a double-headed motor, bevel gear and screw structure to lift the plate and reasonably allocate the internal space of the storage box.

Benefits of technology

Through the effective buffer structure, the vibration of the storage box during movement is significantly reduced, the protein structure of the antibody sample is protected, and the stability and practicality of the storage device are improved.

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Abstract

The utility model relates to the technical field of storage devices, and discloses a safe antibody storage device which comprises a base, a storage box is arranged at the top of the base, a buffer assembly is installed at the bottom of the storage box, and a partition plate assembly is arranged in the storage box. The safe antibody storage device is provided with a connecting shaft, a movable plate, a movable block, a sliding rod, a first spring, a second spring and a damper, the storage box can drive the movable plate to rotate in the up-down vibration process through the arranged connecting shaft, and the movable plate rotates to push the movable block to move; a first spring arranged on one side of the moving block can play a role in buffering movement of the moving block, then vibration of the storage box is buffered to a certain degree, meanwhile, the vibration of the storage box is further buffered under dual cooperation of a second spring and a damper, the buffering effect is greatly improved, and the service life of the storage box is prolonged. And the influence of excessive vibration on the antibody is avoided.
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Description

Technical Field

[0001] The utility model relates to the technical field of storage devices, in particular to a safe storage device for antibodies. Background Art

[0002] Antibody molecules are the most widely used protein molecules in biology and medicine. They are widely used in disease diagnosis, treatment, scientific research and other fields. Antibodies are protective proteins produced by the body due to the stimulation of antigens. Antibodies can recognize a unique feature of a specific foreign object, which is called an antigen.

[0003] Antibodies need to be stored to ensure that they remain active and efficient when binding to target proteins. Antibodies have a strict three-dimensional structure and have evolved to remain active in most biological environments, even when the body suffers large-scale trauma. Constant temperature storage devices are often required to store them safely.

[0004] The prior art patent document with announcement number CN220430860U provides a temperature-adjustable storage device for antibody storage. The storage device can make the storage mechanism more stable when connected to the inside of the placement slot through the abutment plate, and the abutment plate 1 of the clamping mechanism is inserted into the inside of the clamping block, and the abutment plate 2 and the clamping plate are clamped in the inside of the clamping slot. The clamping force is increased by the telescopic device to avoid the storage mechanism inside the placement slot from tipping over when the storage mechanism is moved. This can increase the stability of the placement of the antibody sample and avoid the collapse of the storage device due to the unstable connection between the storage device and the mobile device, which may cause damage to the antibody sample.

[0005] The above-mentioned prior art, although the storage device can make the storage mechanism more stable when connected to the inside of the placement groove, and increase the clamping force by the telescopic device, the stability of the placement of the antibody sample can be increased. However, in the storage device of the patented technology, the antibody sample is placed in a storage box for storage. During the movement, the antibody sample in the storage box will vibrate, and the vibration may cause the protein structure in the antibody sample to change, thereby affecting its ability to bind to the target protein, reducing the practicality of the storage device. Therefore, we need a safe storage device for antibodies. Utility Model Content

[0006] The purpose of the utility model is to provide a safe storage device for antibodies to solve the problem that in the storage device of the patent technology proposed in the above-mentioned background technology, antibody samples are placed in a storage box for storage. During the movement, the antibody samples in the storage box will vibrate, and the vibration may cause changes in the protein structure of the antibody samples, thereby affecting their ability to bind to the target protein, reducing the practicality of the storage device.

[0007] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0008] A safe storage device for antibodies comprises a base, a storage box is arranged on the top of the base, a buffer assembly is installed on the bottom of the storage box, and a partition assembly is arranged inside the storage box;

[0009] The buffer assembly includes a connecting shaft, the inner wall of the connecting shaft is rotatably connected to a movable plate, and the bottom of the movable plate is hinged to a moving block, the inner wall of the moving block is slidably connected to a sliding rod, and the outer surface of the sliding rod is sleeved with a first spring, the inner wall of the base is fixedly connected to a second spring, and the inner wall of the second spring is sleeved with a damper;

[0010] The partition assembly includes a double-headed motor, the output end of the double-headed motor is detachably connected to the first bevel gear through a coupling, and the outer wall of the first bevel gear is meshed with the second bevel gear, the inner wall of the second bevel gear is fixedly connected to a lead screw, and the outer surface of the lead screw is rotatably connected to a placement plate, the inner wall of the storage box is provided with a slide groove, and the inner wall of the slide groove is slidably connected to a slider.

[0011] Preferably, a handle is fixedly connected to one side of the base, a universal wheel is installed at the bottom of the base, and a box door is provided on the front of the storage box.

[0012] Preferably, the connecting shaft forms a movable structure through a movable plate and a movable block, and the movable plate is arranged between the connecting shaft and the movable block.

[0013] Preferably, the moving block forms an elastic structure with the first spring through a sliding rod, and one end of the sliding rod penetrates through the inner wall of the first spring for connection.

[0014] Preferably, the base forms an elastic structure with the storage box through a second spring, and the number of the second springs is two, and the second spring is arranged between the base and the storage box.

[0015] Preferably, the double-headed motor forms a rotating structure through a first bevel gear and a second bevel gear, and the shape and size of the outer wall of the first bevel gear matches the shape and size of the outer wall of the second bevel gear.

[0016] Preferably, the second bevel gear forms a lifting structure through a screw rod and a placement plate, and the external thread of the screw rod matches the internal thread of the placement plate, the shape and size of the inner wall of the slide groove matches the shape and size of one side of the slider, and one side of the slider is connected to the placement plate.

[0017] Compared with the prior art, the utility model has the following beneficial effects: the safe storage device for antibodies,

[0018] First, the utility model is provided with a connecting shaft, a movable plate, a moving block, a sliding rod, a first spring, a second spring and a damper. The connecting shaft is provided so that the storage box can drive the movable plate to rotate during the up and down vibration process. The rotation of the movable plate can push the moving block to move. The first spring provided on one side of the moving block can buffer the movement of the moving block, thereby buffering the vibration of the storage box to a certain extent. At the same time, the vibration of the storage box is further buffered under the dual cooperation of the second spring and the damper, which greatly improves the buffering effect to prevent excessive vibration from affecting the antibody.

[0019] Second, the utility model is provided with a double-headed motor, a first bevel gear, a second bevel gear, a screw, a placement plate, a slide groove and a slider. By starting the double-headed motor, the first bevel gears at both ends can be driven to rotate while driving the second bevel gear to rotate. Then the second bevel gear drives the screw to rotate on the placement plate, so that the placement plate is raised and lowered, which can facilitate the reasonable allocation of the internal space of the storage box to meet different usage requirements. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 This is a schematic diagram of the main structure of the utility model;

[0021] Figure 2 This is a schematic diagram of the front cross-sectional structure of the utility model;

[0022] Figure 3 This is a schematic diagram of the structure of the movable plate and the moving block of the utility model;

[0023] Figure 4 This is a schematic diagram of the structure of the screw rod and the placement plate of the utility model.

[0024] In the figure: 1, base; 2, storage box; 3, buffer assembly; 301, connecting shaft; 302, movable plate; 303, moving block; 304, sliding rod; 305, first spring; 306, second spring; 307, damper; 4, handle; 5, universal wheel; 6, box door; 7, partition assembly; 701, double-headed motor; 702, first bevel gear; 703, second bevel gear; 704, screw rod; 705, placement plate; 706, slide groove; 707, slider. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0026] See also Figure 1 , Figure 2 , Figure 3 and Figure 4 , a safe storage device for antibodies, comprising a base 1, a storage box 2 is arranged on the top of the base 1, a buffer assembly 3 is installed on the bottom of the storage box 2, and a partition assembly 7 is arranged inside the storage box 2;

[0027] The buffer assembly 3 includes a connecting shaft 301, the inner wall of the connecting shaft 301 is rotatably connected to a movable plate 302, and the bottom of the movable plate 302 is hinged with a moving block 303, the inner wall of the moving block 303 is slidably connected to a sliding rod 304, and the outer surface of the sliding rod 304 is sleeved with a first spring 305, the inner wall of the base 1 is fixedly connected to a second spring 306, and the inner wall of the second spring 306 is sleeved with a damper 307;

[0028] The partition assembly 7 includes a double-headed motor 701, the output end of the double-headed motor 701 is detachably connected to the first bevel gear 702 through a coupling, and the outer wall of the first bevel gear 702 is meshed with the second bevel gear 703, the inner wall of the second bevel gear 703 is fixedly connected to a screw rod 704, and the outer surface of the screw rod 704 is rotatably connected to a placement plate 705, the inner wall of the storage box 2 is provided with a slide groove 706, and the inner wall of the slide groove 706 is slidably connected to a slider 707.

[0029] Through the above technical solution, the connecting shaft 301 is set up so that the storage box 2 can drive the movable plate 302 to rotate during the up and down vibration process. The rotation of the movable plate 302 can push the moving block 303 to move. The first spring 305 set on one side of the moving block 303 can buffer the movement of the moving block 303, thereby buffering the vibration of the storage box 2 to a certain extent. At the same time, with the dual cooperation of the second spring 306 and the damper 307, the vibration of the storage box 2 is further buffered, which greatly improves the buffering effect to prevent excessive vibration from affecting the antibody.

[0030] Specifically, a handle 4 is fixedly connected to one side of the base 1 , a universal wheel 5 is installed at the bottom of the base 1 , and a box door 6 is arranged on the front of the storage box 2 .

[0031] Through the above technical solution, it is convenient for the staff to hold the handle 4 and push it forward. The storage device can be moved forward under the action of the universal wheel 5 at the bottom of the base 1, which is convenient for carrying the storage device, and the box door 6 can be opened to take out the antibodies in the storage box 2.

[0032] Specifically, the connecting shaft 301 forms a moving structure through the movable plate 302 and the moving block 303 , and the movable plate 302 is arranged between the connecting shaft 301 and the moving block 303 .

[0033] Through the above technical solution, the storage box 2 can drive the movable plate 302 to rotate through the connecting shaft 301 during the up and down vibration process, and the two movable plates 302 rotate in opposite directions. The rotation of the movable plate 302 drives the moving block 303 to move, thereby achieving the effect of moving the moving block 303.

[0034] Specifically, the moving block 303 forms an elastic structure with the first spring 305 through the sliding rod 304 , and one end of the sliding rod 304 penetrates through the inner wall of the first spring 305 for connection.

[0035] Through the above technical solution, the moving block 303 can slide on the slide rod 304 during the movement, thereby maintaining the stability of the movement of the moving block 303, and the outward movement of the moving block 303 will be restricted by the first spring 305, so that the movement of the moving block 303 is affected by resistance, thereby achieving a certain buffering effect on the vibration of the storage box 2.

[0036] Specifically, the base 1 and the storage box 2 form an elastic structure through the second spring 306 , and the number of the second springs 306 is two, and the second spring 306 is arranged between the base 1 and the storage box 2 .

[0037] Through the above technical solution, the vibration of the storage box 2 can be further buffered through the cooperation of the second spring 306 and the damper 307, thereby increasing the buffering effect and cooperating with the first spring 305 to greatly improve the buffering effect on the storage box 2.

[0038] Specifically, the double-headed motor 701 forms a rotating structure through the first bevel gear 702 and the second bevel gear 703 , and the shape and size of the outer wall of the first bevel gear 702 matches the shape and size of the outer wall of the second bevel gear 703 .

[0039] Through the above technical solution, it is convenient to start the double-headed motor 701 to drive the first bevel gear 702 to rotate and drive the second bevel gear 703 to rotate synchronously. The horizontal rotation of the first bevel gear 702 drives the second bevel gear 703 to rotate vertically, thereby changing the direction of rotation.

[0040] Specifically, the second bevel gear 703 forms a lifting structure with the placement plate 705 through the screw rod 704, and the external thread of the screw rod 704 matches the internal thread of the placement plate 705, the shape and size of the inner wall of the slide groove 706 matches the shape and size of one side of the slider 707, and one side of the slider 707 is connected to the placement plate 705.

[0041] Through the above technical solution, the second bevel gear 703 is conveniently rotated to drive the screw rod 704 to rotate in the placement plate 705, and then the placement plate 705 is lifted up and down. While the placement plate 705 is lifted and lowered, it slides in the slide groove 706 through the slider 707 to remain stable, which can facilitate the reasonable allocation of the internal space of the storage box 2.

[0042] Working principle: when using the antibody safety storage device, first, during the movement of the storage device, the vibration generated by the storage box 2 will drive the movable plate 302 to rotate through the connecting shaft 301, and the rotation of the movable plate 302 will drive the moving block 303 to move, and then the moving block 303 will slide on the slide bar 304 during the movement, and the outward movement of the moving block 303 will be restricted by the first spring 305, so that the movement of the moving block 303 is affected by resistance, and then the vibration of the storage box 2 can be buffered to a certain extent. At the same time, the bottom of the storage box 2 can be further buffered by the cooperation of the second spring 306 and the damper 307, thereby increasing the buffering effect, which is comparable to the first spring 305. The mutual cooperation greatly improves the buffering effect of the storage box 2. When the internal space of the storage box 2 is allocated, the double-headed motor 701 is started first. The double-headed motor 701 drives the first bevel gears 702 at both ends to rotate. The first bevel gear 702 drives the second bevel gear 703 to rotate due to the meshing action. The second bevel gear 703 drives the screw rod 704 to rotate. The rotation of the screw rod 704 drives the placement plate 705 to move up and down. While the placement plate 705 is being lifted and lowered, it slides in the slide groove 706 through the slider 707 to maintain stability, and then the internal space of the storage box 2 can be conveniently allocated reasonably. This completes all the work. The content not described in detail in this manual belongs to the existing technology known to professional and technical personnel in this field.

[0043] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit thereof, and the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A safe storage device for antibodies, comprising a base (1), characterized in that: A storage box (2) is arranged on the top of the base (1), a buffer assembly (3) is installed on the bottom of the storage box (2), and a partition assembly (7) is arranged inside the storage box (2); The buffer assembly (3) comprises a connecting shaft (301), the inner wall of the connecting shaft (301) is rotatably connected to a movable plate (302), and the bottom of the movable plate (302) is hinged with a moving block (303), the inner wall of the moving block (303) is slidably connected to a sliding rod (304), and the outer surface of the sliding rod (304) is sleeved with a first spring (305), the inner wall of the base (1) is fixedly connected to a second spring (306), and the inner wall of the second spring (306) is sleeved with a damper (307); The partition assembly (7) comprises a double-headed motor (701), the output end of the double-headed motor (701) is detachably connected to a first bevel gear (702) via a coupling, and the outer wall of the first bevel gear (702) is meshed with a second bevel gear (703), the inner wall of the second bevel gear (703) is fixedly connected to a screw rod (704), and the outer surface of the screw rod (704) is rotatably connected to a placement plate (705), and the inner wall of the storage box (2) is provided with a slide groove (706), and the inner wall of the slide groove (706) is slidably connected to a slider (707).

2. The safe storage device for antibodies according to claim 1, characterized in that: A handle (4) is fixedly connected to one side of the base (1), a universal wheel (5) is installed at the bottom of the base (1), and a box door (6) is arranged on the front of the storage box (2).

3. The safe storage device for antibodies according to claim 1, characterized in that: The connecting shaft (301) forms a movable structure through a movable plate (302) and a movable block (303), and the movable plate (302) is arranged between the connecting shaft (301) and the movable block (303).

4. The safe storage device for antibodies according to claim 1, characterized in that: The moving block (303) forms an elastic structure with the first spring (305) through the sliding rod (304), and one end of the sliding rod (304) penetrates the inner wall of the first spring (305) for connection.

5. The safe storage device for antibodies according to claim 1, characterized in that: The base (1) and the storage box (2) form an elastic structure through the second spring (306), and the number of the second springs (306) is two, and the second springs (306) are arranged between the base (1) and the storage box (2).

6. The safe storage device for antibodies according to claim 1, characterized in that: The double-headed motor (701) forms a rotating structure through the first bevel gear (702) and the second bevel gear (703), and the shape and size of the outer wall of the first bevel gear (702) match the shape and size of the outer wall of the second bevel gear (703).

7. The safe storage device for antibodies according to claim 1, characterized in that: The second bevel gear (703) forms a lifting structure with the placement plate (705) through the screw rod (704), and the external thread of the screw rod (704) matches the internal thread of the placement plate (705), the shape and size of the inner wall of the slide groove (706) matches the shape and size of one side of the slider (707), and one side of the slider (707) is connected to the placement plate (705).

Citation Information

Patent Citations

  • Temperature-adjustable storage equipment for antibody storage

    CN220430860U