Reaction kettle dropwise adding device

Abstract

The utility model relates to the technical field of pharmaceutical chemical equipment, and provides a reaction kettle dropwise adding device which is applied to an enamel kettle, the other side of the top end of the enamel kettle is fixedly connected with a main dropwise adding pipeline, the upper end of one side of the main dropwise adding pipeline is fixedly connected with a control valve, and the lower end of the other side of the main dropwise adding pipeline is fixedly connected with a charging valve. By arranging the feeding valve, the auxiliary dropwise adding pipeline, the main dropwise adding pipeline and the control valve, alkali liquor is firstly added through the main dropwise adding pipeline to adjust the PH value, when the PH value is about to reach the range, the control valve is closed, and the auxiliary dropwise adding pipeline extends to the outside of the communicating seat. The alkali liquor is slowly and uniformly added from the auxiliary dropwise adding pipeline with the small inner diameter, the problem that the PH value exceeds the specified range due to the fact that the dropwise adding speed of the alkali liquor is too high is solved, meanwhile, it can be avoided that an operator frequently adjusts the size of a feeding valve for a long time to control the flow speed as much as possible, and the operation environment is greatly improved.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmaceutical chemical equipment, in particular to a reaction kettle dropping device. Background Art

[0002] Adjusting pH value is a common behavior in the chemical industry. Some dripping acceleration is too fast, resulting in uneven system and large measurement error, but at the same time, pH must be maintained within the range. At present, the main methods of dripping are pure manual, flow meter, metering pump, etc. The measurement accuracy is poor and is greatly affected by other factors. Flow control depends on operators, the work intensity of employees is high, and the control is unstable, making it difficult to ensure product quality and production safety.

[0003] After searching, the existing patent (Announcement No.: CN217490787U) discloses a reactor dripping device, including a vertically arranged main pipeline, at least three branch pipelines are arranged at the lower end of the main pipeline, and the multiple branch pipelines are evenly distributed circumferentially with the main pipeline as the center in the horizontal plane, and one end of the multiple branch pipelines is commonly connected to the main pipeline, a spray dripping nozzle is installed below the branch pipeline, and a pressure control device is arranged at the top of the main pipeline. The beneficial effect of the utility model is that the droplets of the dripping liquid are sprayed on the surface of the reaction liquid in a mist form, which increases the specific surface area of ​​the droplets, makes the contact between the dripping liquid and the reaction liquid more sufficient, avoids the local excessive temperature caused by the reaction lag, and at the same time, the spray dripping nozzle makes the pipeline have a certain liquid pressure, cooperates with the pressure control device to control the pressure so as to control the amount of material added and the reaction time, so that the reaction process is stable and controllable, the temperature is stable, and the quality and yield of the product are improved.

[0004] However, in the above scheme, the structure is relatively complicated, resulting in inconvenience in installation. The traditional manual dripping method has poor metering accuracy and is greatly affected by other factors. Flow control relies on operators, which increases the workload of employees. In addition, the control is unstable, making it difficult to ensure product quality and production safety.

[0005] In view of this, the utility model proposes a reaction kettle dripping device. Utility Model Content

[0006] The utility model provides a reaction kettle dripping device, which solves the problems of complex structure and inconvenient dripping adjustment in the related technology.

[0007] The technical solution of the utility model is as follows: a reaction kettle dripping device is applied to an enamel kettle, one side of the top of the enamel kettle is fixedly connected to a manhole cover, a driving motor is fixedly connected at the middle position of the top of the enamel kettle, the output end of the driving motor extends to the interior of the enamel kettle and is fixedly connected to an agitator through a coupling, a main dripping pipe is fixedly connected to the other side of the top of the enamel kettle, the upper end of one side of the main dripping pipe is fixedly connected to a control valve, the lower end of the other side of the main dripping pipe is fixedly connected to a feeding valve, the upper and lower ends of the other side of the main dripping pipe are fixedly connected to a connecting seat, one side of the inside of the connecting seat is movably connected to a secondary dripping pipe extending to the outside of the connecting seat, and a mounting assembly is provided on one side of the connecting seat, and alkali solution is slowly and evenly added by using the secondary dripping pipe with a thinner inner diameter to avoid the problem of pH exceeding the specified range due to excessive alkali solution drop acceleration, and at the same time, it can also try to avoid the operator frequently adjusting the size of the feeding valve for a long time to control the flow rate, thereby greatly improving the operating environment.

[0008] Preferably, the cross-section of the auxiliary dripping pipe is in an inverted U shape, and the auxiliary dripping pipe is made of stainless steel, which can effectively control the inflow speed of the alkali solution.

[0009] Preferably, the main dripping pipe is inclined at an angle of 20 degrees to the vertical direction, and the bottom end of the main dripping pipe is connected to the inside of the enamel kettle, so as to facilitate the addition of alkali solution to achieve pH value adjustment.

[0010] The top end of the support leg is fixedly connected to the support frame, and the top end of the support leg is fixedly connected to the support frame by the spring, and the top end of the support leg is fixedly connected to the support frame by the spring.

[0011] Preferably, the cross-sectional area of ​​the sealing disk is larger than the cross-sectional area of ​​the internal opening of the connecting seat, and the cross-sectional shape of the sealing disk is O-shaped, so that a preliminary clamping seal can be achieved on one end of the connecting seat.

[0012] Preferably, anti-skid convex strips are fixedly connected at equal angles on both sides of the surface of the sealing disk, and the cross-section of the anti-skid convex strips is arc-shaped, which is convenient for the user to insert one end of the auxiliary drip pipe into the connecting seat through the sealing disk.

[0013] Preferably, a sliding engagement structure is formed between the clamping block and the inside of the clamping slot, and the cross-sections of the clamping slot and the clamping block are rectangular, thereby improving the firmness of the auxiliary dripping pipe being clamped to the inside of the connecting seat.

[0014] Preferably, a snap-fit ​​structure is formed between the mounting block and the inside of the mounting hole, and the height of the mounting block is smaller than the depth of the inside of the mounting slot, thereby improving the stability and firmness of the snap-fit ​​between the snap-fit ​​block and the inside of the slot.

[0015] Preferably, a sliding structure is formed between the sliding block and the interior of the mounting groove, and the shape of the mounting groove and the sliding block in a top view is a cross, so that the mounting block slides up and down more smoothly.

[0016] Preferably, a sealing ring is fixedly connected to the upper and lower ends of one side of the surface of the auxiliary dripping pipe, and the cross-section of the sealing ring is O-shaped to ensure the sealing performance of the auxiliary dripping pipe after being inserted and engaged with the connecting seat.

[0017] The working principle and beneficial effects of the utility model are:

[0018] 1. In the utility model, the feeding valve, the auxiliary dripping pipe, the main dripping pipe and the control valve are provided. The feeding valve and the control valve are opened first, and then the alkali solution is quickly added through the main dripping pipe to adjust the pH value. When the pH value is about to reach the range, the control valve is closed to allow the alkali solution to flow into the auxiliary dripping pipe. At this time, the auxiliary dripping pipe with a thinner inner diameter is used to effectively control the inflow speed of the alkali solution, and avoid the problem that the pH value exceeds the specified range due to the excessively fast dripping acceleration of the alkali solution. At the same time, it can also avoid the operator frequently adjusting the size of the feeding valve to control the flow rate for a long time, which greatly improves the operating environment. At the same time, the structure of the device is simpler, the disassembly and assembly are more convenient, and the pH value adjustment system is more uniform, which improves its practicality.

[0019] 2. The utility model provides an installation assembly, utilizes one end of the auxiliary dripping pipe to engage with the inside of the connecting seat, and then utilizes the engagement of the clamping block with the inside of the clamping groove and the engagement of the mounting block with the inside of the mounting hole, so as to realize the rapid and firm disassembly and fixation between the auxiliary dripping pipe and the connecting seat, facilitates the disassembly and maintenance or replacement of the auxiliary dripping pipe, makes the disassembly and assembly of the auxiliary dripping pipe more convenient, reduces the difficulty of disassembly and assembly for the staff, and can use a sealing ring to ensure the sealing of the auxiliary dripping pipe and the connecting seat after insertion and engagement, avoids the leakage of alkali solution, and improves its practicality. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The utility model is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0021] Figure 1 It is a front view cross-sectional structural schematic diagram of the utility model;

[0022] Figure 2 This is a schematic diagram of the overall structure of the utility model;

[0023] Figure 3 This is a schematic diagram of the overall structure of the utility model when viewed from above;

[0024] Figure 4 This is a structural schematic diagram of the main dripping pipeline of the utility model;

[0025] Figure 5 It is a schematic diagram of an exploded and enlarged structure of a local section of the installation component of the utility model.

[0026] In the figure: 1. driving motor; 2. manhole cover; 3. enamel kettle; 4. agitator; 5. feeding valve; 6. auxiliary dripping pipe; 7. connecting seat; 8. main dripping pipe; 9. mounting assembly; 901. sealing ring; 902. sealing disk; 903. mounting seat; 904. mounting groove; 905. clamping groove; 906. anti-skid convex strip; 907. mounting hole; 908. clamping block; 909. mounting block; 910. sliding block; 911. mounting spring; 912. mounting rod; 10. control valve. DETAILED DESCRIPTION

[0027] The following will be combined with the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0028] Example 1

[0029] The preferred embodiment of the reaction kettle dropping device provided by the utility model is as follows Figures 1 to 5As shown: a reaction kettle dripping device is applied to an enamel kettle 3, one side of the top of the enamel kettle 3 is fixedly connected to a manhole cover 2, a driving motor 1 is fixedly connected to the middle position of the top of the enamel kettle 3, the output end of the driving motor 1 extends to the inside of the enamel kettle 3 and is fixedly connected to a stirrer 4 through a coupling, a main dripping pipe 8 is fixedly connected to the other side of the top of the enamel kettle 3, the upper end of one side of the main dripping pipe 8 is fixedly connected to a control valve 10, the lower end of the other side of the main dripping pipe 8 is fixedly connected to a feeding valve 5, the upper and lower ends of the other side of the main dripping pipe 8 are fixedly connected to a connecting seat 7, one side of the inside of the connecting seat 7 is movably connected to an auxiliary dripping pipe 6 extending to the outside of the connecting seat 7, and one side of the connecting seat 7 is provided with a mounting assembly 9, and the auxiliary dripping pipe 6 with a thinner inner diameter is used to slowly and evenly add alkali solution to avoid the problem of pH value exceeding the specified range due to excessive alkali solution drop acceleration.

[0030] In this embodiment, the cross-section of the auxiliary dripping pipe 6 is in an inverted U shape, and the auxiliary dripping pipe 6 is made of stainless steel. The auxiliary dripping pipe 6 with a thinner inner diameter and an inverted U shape can effectively control the inflow speed of the alkali solution.

[0031] In this embodiment, the main dripping pipe 8 is inclined at an angle of twenty degrees to the vertical direction, and the bottom end of the main dripping pipe 8 is connected to the inside of the enamel kettle 3. The inclined main dripping pipe 8 is used to facilitate the addition of alkali solution to achieve pH value adjustment.

[0032] Example 2

[0033] On the basis of Example 1, a preferred embodiment of the reactor dropping device provided by the utility model is as follows Figures 1 to 5 As shown: the mounting assembly 9 includes a sealing disk 902, which is fixedly connected to the upper and lower ends of one side of the surface of the auxiliary dripping pipe 6, and the upper end of one side of the sealing disk 902 is fixedly connected to a clamping block 908, and the top of the clamping block 908 is provided with a mounting hole 907, and the upper end of one side of the inner side of the connecting seat 7 is provided with a clamping groove 905, and one side of the top of the connecting seat 7 is fixedly connected to a mounting seat 903, and the mounting seat 903 is provided with a mounting groove 904, and the interior of the mounting groove 904 is movably connected to a sliding block 910, and the bottom of the sliding block 910 is fixedly connected to a mounting extending to the inside of the clamping groove 905 Block 909, the top of the sliding block 910 is fixedly connected with a mounting rod 912 extending to the outside of the mounting seat 903, the surface of the mounting rod 912 at the top of the sliding block 910 is wound with a mounting spring 911, the top of the mounting spring 911 is fixedly connected to the inner top wall of the mounting groove 904, and one end of the auxiliary drip pipe 6 is engaged with the inside of the connecting seat 7, and then the engagement of the clamping block 908 with the inside of the clamping groove 905 and the engagement of the mounting block 909 with the inside of the mounting hole 907 are used to achieve quick and firm disassembly and assembly and fixation between the auxiliary drip pipe 6 and the connecting seat 7, which is convenient for disassembly and assembly, maintenance or replacement of the auxiliary drip pipe 6.

[0034] In this embodiment, the cross-sectional area of ​​the sealing disk 902 is larger than the cross-sectional area of ​​the internal opening of the connecting seat 7. The cross-sectional shape of the sealing disk 902 is O-shaped. By using the larger O-shaped sealing disk 902, a preliminary clamping seal can be achieved on one end of the connecting seat 7.

[0035] In this embodiment, anti-slip ridges 906 are fixedly connected at equal angles on both sides of the surface of the sealing disk 902. The cross-section of the anti-slip ridges 906 is arc-shaped. The arc-shaped anti-slip ridges 906 are used to increase the contact friction between the user's fingers and the sealing disk 902, making it easier for the user to insert one end of the auxiliary drip pipe 6 through the sealing disk 902 into the connecting seat 7.

[0036] In this embodiment, a sliding engagement structure is formed between the block 908 and the interior of the slot 905. The cross-sections of the slot 905 and the block 908 are rectangular. The engagement of the rectangular block 908 with the interior of the slot 905 improves the firmness of the auxiliary drip pipe 6 being engaged with the interior of the connecting seat 7.

[0037] In this embodiment, a snap-fit ​​structure is formed between the mounting block 909 and the interior of the mounting hole 907. The height of the mounting block 909 is less than the depth of the interior of the mounting groove 904. The snap-fit ​​between the mounting block 909 and the interior of the mounting hole 907 is used to improve the stability and firmness of the snap-fit ​​between the snap-fit ​​block 908 and the interior of the snap-fit ​​groove 905.

[0038] In this embodiment, a sliding structure is formed between the sliding block 910 and the inside of the mounting groove 904. The shape of the mounting groove 904 and the sliding block 910 in the top view is a cross. The sliding of the cross-shaped sliding block 910 inside the mounting groove 904 makes the up and down sliding of the mounting block 909 smoother.

[0039] In addition, a sealing ring 901 is fixedly connected to the upper and lower ends of one side of the surface of the auxiliary dripping pipe 6. The cross-section of the sealing ring 901 is O-shaped. The O-shaped sealing ring 901 is used to ensure the sealing of the auxiliary dripping pipe 6 and the connecting seat 7 after insertion and engagement.

[0040] The working principle and use process of the utility model: When synthesizing the new nucleoside reverse transcriptase inhibitor tenofovir PMPA in the workshop, due to subsequent needs, the PMPA that has been acid-lyzed needs to be adjusted for pH crystallization. PMPA has very high requirements for pH value, and it is not acceptable to be too acidic or too alkaline. Alkaline solution is added to the PMPA that has been acid-lyzed in the enamel kettle 3. Since the solubility of PMPA in acidic or alkaline aqueous phases is relatively large, less PMPA is precipitated and dissolved in acidic or alkaline water. The utility model first opens the feeding valve 5 and the control valve 10, and then quickly adds alkali solution through the main dripping pipe 8 to achieve pH value adjustment. When the pH value is about to reach the range, the control valve 10 is closed to allow the alkali solution to flow into the auxiliary dripping pipe 6. At this time, the auxiliary dripping pipe 6 with a thinner inner diameter can effectively control the inflow speed of the alkali solution, avoiding the problem that the pH value exceeds the specified range due to the excessive acceleration of the alkali solution dripping. At the same time, it can also try to avoid the operator frequently adjusting the size of the feeding valve 5 for a long time to control the flow rate, which greatly improves the operating environment;

[0041] At the same time, the sliding block 910 and the mounting block 909 can be driven to slide and compress the mounting spring 911 until they are completely disengaged from the inside of the mounting hole 907 by pulling the mounting rod 912, and then the auxiliary drip pipe 6 is pulled hard to separate it from the inside of the connecting seat 7, which is convenient for maintenance or replacement of the auxiliary drip pipe 6. During installation, the mounting rod 912 is first pulled to make the mounting block 909 rise to the inside of the mounting groove 904, and then one end of the auxiliary drip pipe 6 is inserted into the inside of the connecting seat 7, and the clamping block 908 is clamped into the inside of the clamping groove 905, and then the mounting rod 912 is released, and the elastic force of the mounting spring 911 is used to make the mounting block 909 clamped into the inside of the mounting hole 907, thereby achieving a firm clamping fixation between the auxiliary drip pipe 6 and the connecting seat 7, and the sealing ring 901 can be used to ensure the sealing of the auxiliary drip pipe 6 and the connecting seat 7 after insertion and clamping.

[0042] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A reaction kettle dripping device, applied to an enamel kettle (3), characterized in that: A manhole cover (2) is fixedly connected to one side of the top of the enamel kettle (3); a driving motor (1) is fixedly connected to the middle position of the top of the enamel kettle (3); the output end of the driving motor (1) extends to the inside of the enamel kettle (3) and is fixedly connected to the stirrer (4) via a coupling; a main dripping pipe (8) is fixedly connected to the other side of the top of the enamel kettle (3); a control valve (10) is fixedly connected to the upper end of one side of the main dripping pipe (8); a feeding valve (5) is fixedly connected to the lower end of the other side of the main dripping pipe (8); a connecting seat (7) is fixedly connected to the upper and lower ends of the other side of the main dripping pipe (8); a secondary dripping pipe (6) extending to the outside of the connecting seat (7) is movably connected to one side of the inside of the connecting seat (7); and a mounting assembly (9) is provided on one side of the connecting seat (7).

2. A reaction kettle dropping device according to claim 1, characterized in that: The cross-section of the auxiliary dripping pipe (6) is in an inverted U shape, and the auxiliary dripping pipe (6) is made of stainless steel.

3. A reaction kettle dropping device according to claim 1, characterized in that: The main dripping pipe (8) has an inclination angle of 20 degrees with respect to the vertical direction, and the bottom end of the main dripping pipe (8) is connected to the inside of the enamel kettle (3).

4. A reaction kettle dropping device according to claim 1, characterized in that: The mounting assembly (9) comprises a sealing disc (902), wherein the sealing disc (902) is fixedly connected to the upper end and the lower end of one side of the surface of the auxiliary dripping pipe (6), the upper end of one side of the sealing disc (902) is fixedly connected to a clamping block (908), the top end of the clamping block (908) is provided with a mounting hole (907), the upper end of one side of the interior of the connecting seat (7) is provided with a clamping groove (905), the top side of the connecting seat (7) is fixedly connected to a mounting seat (903), the interior of the mounting seat (903) is provided with a mounting groove (904), the interior of the installation groove (904) is movably connected with a sliding block (910), the bottom end of the sliding block (910) is fixedly connected with a mounting block (909) extending to the interior of the card slot (905), the top end of the sliding block (910) is fixedly connected with a mounting rod (912) extending to the outside of the mounting seat (903), the surface of the mounting rod (912) at the top end of the sliding block (910) is wound with a mounting spring (911), and the top end of the mounting spring (911) is fixedly connected to the top wall of the installation groove (904).

5. A reaction kettle dropping device according to claim 4, characterized in that: The cross-sectional area of ​​the sealing disk (902) is greater than the cross-sectional area of ​​the internal opening of the connecting seat (7), and the cross-sectional shape of the sealing disk (902) is O-shaped.

6. A reaction kettle dropping device according to claim 4, characterized in that: Anti-skid convex strips (906) are fixedly connected at equal angles on both sides of the surface of the sealing disk (902), and the cross-section of the anti-skid convex strips (906) is in the shape of an arc.

7. A reaction kettle dropping device according to claim 4, characterized in that: A sliding engagement structure is formed between the clamping block (908) and the interior of the clamping slot (905), and the cross-sections of the clamping slot (905) and the clamping block (908) are rectangular.

8. A reaction kettle dropping device according to claim 4, characterized in that: A snap-fit ​​structure is formed between the mounting block (909) and the interior of the mounting hole (907), and the height of the mounting block (909) is smaller than the depth of the interior of the mounting groove (904).

9. A reaction kettle dropping device according to claim 4, characterized in that: A sliding structure is formed between the sliding block (910) and the interior of the mounting groove (904); the mounting groove (904) and the sliding block (910) are in a cross shape in a top view.

10. A reaction kettle dropping device according to claim 1, characterized in that: The upper end and the lower end of one side of the surface of the auxiliary dripping pipe (6) are fixedly connected with a sealing ring (901), and the cross-section of the sealing ring (901) is in an O-shape.

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