Reagent heating device
By setting a model structure and a breathable structure on the upper surface of the heating fixture of the reagent heating device, the problem of inconvenient pick-up and placement of the reagent bearing container in the prior art is solved, and the combination of efficient heating and convenient operation is achieved.
Patent Information
- Application Number
- CN202421336594.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-12
- Publication Date
- 2025-03-21
- Estimated Expiration
- 2034-06-12
AI Technical Summary
While the existing reagent heating devices improve heat conduction efficiency, they cause inconvenience to pick up and place the reagent carrier container, especially due to the fitting of the heating fixture and the lower surface of the reagent carrier container, which increases the difficulty of operation.
A reagent heating device is designed, and the upper surface of the heating fixture is provided with a model structure with the reagent bearing container, and an air permeable structure is added to this structure to form a gap to facilitate exhaust and air circulation, thereby facilitating the pick-up and placement of the reagent bearing container.
By increasing the contact area and breathable structure with the reagent bearing container, the reagent heating efficiency is improved, while the reagent bearing container is easier to pick and place, and the working efficiency of the genetic detection equipment is improved.
Smart Images
Figure CN222642062U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of reagent detection, in particular to a reagent heating device. Background Art
[0002] Genetic testing equipment has many uses in medical treatment, cancer, etc. The steps of genetic testing are relatively rigorous and complicated. For example, the pipette tip needs to be positioned on the reagent to drip the fluorescent agent, and subsequent heating and cooling steps are required.
[0003] Genetic testing equipment needs to heat the reagent to a predetermined temperature within a specified time. For example, the reagent can be heated to the required temperature of 70°C within 10 minutes. A reagent heating device needs to be configured in the genetic testing equipment.
[0004] In the prior art, in order to improve heat conduction, a heating jig is provided in the reagent heating device. The usual heating jig improves the heating efficiency by increasing the contact area with the reagent carrying container. However, the reagent carrying container is generally a collection of multiple reagent holding units, for example, a PCR plate, which is more commonly used with 96 or 384 wells. In this case, although the heating jig improves the heating efficiency, due to the presence of multiple reagent holding units, the heating jig is attached to the lower surface of the reagent carrying container, making it inconvenient to take and put the reagent carrying container. Utility Model Content
[0005] The utility model provides a reagent heating device, which aims to facilitate the taking and placing of a reagent carrying container while ensuring the reagent heating efficiency.
[0006] The present invention provides a reagent heating device, comprising:
[0007] The base 11 is provided with a sink;
[0008] A heating plate 12 is arranged in the sink of the base 11;
[0009] The heating fixture 13 is disposed on the base 11 , and its upper surface is configured to have a conformal structure with the reagent carrying container, and a breathable structure is disposed on the conformal structure.
[0010] Optionally, the heating fixture 13 includes a plurality of vertical bodies 131 , and gaps exist between adjacent vertical bodies 131 to form a breathable structure.
[0011] Optionally, the gap between adjacent vertical bodies 131 is 20% to 25% of the diameter of the reagent containing unit in the reagent carrying container.
[0012] Optionally, the heating fixture 13 is made of metal material.
[0013] Optionally, the reagent heating device further includes a heat insulating sheet 14 , which is disposed under the heating sheet 12 and is in contact with the lower surface of the heating sheet 12 .
[0014] Optionally, the heat insulation sheet 14 is provided with a positioning hole 141 , and the sink is provided with a positioning column 111 matched with the positioning hole 141 .
[0015] Optionally, the reagent heating device further includes a fixing component 15 connected to the base 11 and used for fixing the heating fixture 13 .
[0016] Optionally, a notch 112 is formed on the side wall and the bottom plate of the base 11 .
[0017] Optionally, the reagent heating device further includes a bracket 16 , which is disposed below the base 11 and fixedly connected to the base 11 .
[0018] Optionally, the reagent heating device further includes a fixing seat 17 disposed below the bracket 16 and fixedly connected to the bracket 16 , and the fixing seat 17 includes a fixing pin 171 extending downward.
[0019] A reagent heating device provided by an embodiment of the utility model increases the contact area with the heated reagent carrying container by means of a heating jig, and provides a breathable structure, thereby solving the problem of inconvenience in taking and placing the reagent carrying container due to the adhesion between the heating jig and the lower surface of the reagent carrying container, and achieving the effect of facilitating the taking and placing of the reagent carrying container on the heating jig. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 A schematic diagram of the structure of a reagent heating device provided in an embodiment of the utility model;
[0021] Figure 2 A schematic diagram of the structure of a reagent heating device provided by an embodiment of the utility model without a heating fixture;
[0022] Figure 3 A schematic structural diagram of a reagent heating device provided in an embodiment of the utility model without a heating plate and a heat insulating plate. DETAILED DESCRIPTION
[0023] The present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It is to be understood that the specific embodiments described herein are only used to explain the present invention, rather than to limit the present invention. It should also be noted that, for ease of description, only the parts related to the present invention, rather than all structures, are shown in the accompanying drawings.
[0024] The present invention provides a reagent heating device. Figure 1 , Figure 2 and Figure 3 As shown, including:
[0025] The base 11 is provided with a sink;
[0026] A heating plate 12 is arranged in the sink of the base 11;
[0027] The heating fixture 13 is disposed on the base 11 , and its upper surface is configured to have a conformal structure with the reagent carrying container, and a breathable structure is disposed on the conformal structure.
[0028] The overall shape of the reagent carrying container is rectangular, including multiple reagent holding units. For example, a 96-well PCR plate has 96 reagent tubes arranged in 12×8. The base 11 can also be rectangular, similar to the reagent carrying container, and the area can be slightly larger to support the reagent carrying container. The base 11 is provided with a sink to accommodate the heating plate 12. Figure 2 In the embodiment, the heating plate 12 is also generally rectangular in shape, and a temperature sensor can be integrated in the heating plate 12 to detect the temperature of the heating plate and facilitate the control of the heating temperature of the reagent. The heating fixture 13 is arranged on the base 11, and its upper surface is in a profiled structure with the lower surface of the reagent carrying container, thereby increasing the contact area with the reagent carrying container and improving the efficiency of heat conduction. In addition, a breathable structure is arranged on the profiled structure, because the upper surface of the heating fixture 13 is in a profiled structure with the lower surface of the reagent carrying container, then, after the reagent carrying container is placed on the heating fixture 13, the two fit each other, and the air between the two is discharged, and the breathable structure is arranged to facilitate exhaust, so that the reagent carrying container can be smoothly placed on the heating fixture 13; and when the reagent carrying container is removed, the breathable structure can also allow air to enter between the reagent carrying container and the heating fixture, so that the reagent carrying container will not be difficult to remove from the heating fixture, thereby improving the working efficiency of the gene detection device.
[0029] Optionally, the heating fixture 13 includes a plurality of vertical bodies 131 , and gaps exist between adjacent vertical bodies 131 to form a breathable structure.
[0030] Taking a PCR plate as an example, a plurality of vertical bodies 131 have curved side surfaces to fit a single reagent tube of the PCR plate, and the side surfaces of the vertical bodies 131 at the outer edges facing outwards may be flat. Gaps exist between the vertical bodies 131 to form a breathable structure.
[0031] Optionally, the gap between adjacent vertical bodies 131 is 20% to 25% of the diameter of the reagent containing unit in the reagent carrying container.
[0032] Taking a 96-well PCR plate as an example, the outer diameter of a single reagent tube is 9 mm, and the gap can preferably be set to 2 mm.
[0033] Optionally, the heating fixture 13 is made of metal material, wherein the material of the heating fixture 13 can be selected from 6061 aluminum alloy.
[0034] Optionally, the reagent heating device further includes a heat insulating sheet 14 , which is disposed under the heating sheet 12 and is in contact with the lower surface of the heating sheet 12 .
[0035] The shape of the heat insulating sheet 14 can match the shape of the inner wall of the sink, and it is arranged under the heating sheet 12 to play a heat insulating role, and a plastic material can be selected.
[0036] Optionally, the heat insulation sheet 14 is provided with a positioning hole 141, and the sink is provided with a positioning column 111 that matches the positioning hole 141. The positioning hole 141 may be provided at each of the four corners of the heat insulation sheet 14.
[0037] Optionally, the reagent heating device further includes a fixing component 15 connected to the base 11 and used to fix the heating fixture 13. Figure 1 As shown in , the fixing assembly may include a claw 151, the end of which is rotatably connected to the base 11 via a connecting shaft passing through the base 11, and the connecting rod 152 can rotate under the drive of an external driving mechanism and drive the claw 151 to clamp and release the heating jig.
[0038] Optionally, a notch 112 is formed on the side wall and the bottom plate of the base 11 .
[0039] in, Figure 3 The notch 112 shown in the figure facilitates the placement and removal of the heating sheet 12 and the heat insulating sheet 14.
[0040] Optionally, the reagent heating device further includes a bracket 16 , which is disposed below the base 11 and fixedly connected to the base 11 .
[0041] Optionally, the reagent heating device further comprises a fixing seat 17 disposed below the bracket 16 and fixedly connected to the bracket 16, wherein the fixing seat 17 comprises a fixing pin 171 extending downwardly. The fixing pin 171 can be used to fix the reagent heating device in the gene detection device.
[0042] Some directional words are defined in the present utility model. Unless otherwise specified, the directional words used, such as "up", "down", "left", "right", "inside" and "outside", are used for ease of understanding and therefore do not constitute limitations on the protection scope of the present utility model.
[0043] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.
[0044] In the description of the present invention, unless otherwise clearly specified and limited, the terms "connected", "connected", and "fixed" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
Claims
1. A reagent heating device, characterized in that: include: The base (11) is provided with a sink; A heating plate (12) is arranged in the sink of the base (11); The heating fixture (13) is arranged on the base (11), and its upper surface is arranged to be a structure conforming to the reagent carrying container, and a breathable structure is arranged on the conforming structure.
2. The reagent heating device according to claim 1, characterized in that: The heating jig (13) comprises a plurality of vertical bodies (131), and gaps exist between adjacent vertical bodies (131) to form a breathable structure.
3. The reagent heating device according to claim 2, characterized in that: The gap between adjacent vertical bodies (131) is 20% to 25% of the diameter of the reagent containing unit in the reagent carrying container.
4. The reagent heating device according to any one of claims 1 to 3, characterized in that: The heating fixture (13) is made of metal material.
5. The reagent heating device according to claim 1, characterized in that: It also includes a heat insulation sheet (14), which is arranged under the heating sheet (12) and is in contact with the lower surface of the heating sheet (12).
6. The reagent heating device according to claim 5, characterized in that: The heat insulation sheet (14) is provided with a positioning hole (141), and the sink is provided with a positioning column (111) that matches the positioning hole (141).
7. The reagent heating device according to claim 1, characterized in that: It also includes a fixing component (15) connected to the base (11) and used to fix the heating fixture (13).
8. The reagent heating device according to claim 1, characterized in that: The side wall and the bottom plate of the base (11) are provided with notches (112).
9. The reagent heating device according to claim 1, characterized in that: It also includes a bracket (16), which is arranged below the base (11) and is fixedly connected to the base (11).
10. The reagent heating device according to claim 9, characterized in that: It also includes a fixing seat (17) disposed below the bracket (16) and fixedly connected to the bracket (16), wherein the fixing seat (17) includes a fixing pin (171) extending downward.