Platelet-rich plasma separation device

Abstract

The utility model belongs to the technical field of separation devices, and particularly relates to a platelet-rich plasma separation device which comprises a barrel, an upper cover and a piston, the barrel comprises a bin and a separation part, the upper portion of the bin is connected with the upper cover, and the piston is contained in the bin; the top end of the separation part can abut against the upper cover, and the bottom end of the separation part is connected with the inner wall of the cylinder body; the top end of the partition part is slightly lower than the top end of the side wall of the barrel, the partition part divides the bin into a first bin body and a second bin body which can be communicated with each other, a channel is formed at the communication position of the first bin body and the second bin body, and the partition part is matched with the upper cover to open or close the channel. Plasma can be centrifuged once in the first bin body and the second bin body respectively, an external extraction device extracts supernate from the second bin body, the left part is PRP, and the plasma extraction device has the advantages of being convenient to operate, high in extraction efficiency and high in extraction precision.

Description

Technical Field

[0001] The present application belongs to the technical field of separation devices, and specifically relates to a platelet-rich plasma separation device. Background Art

[0002] Platelet rich plasma (PRP) is a platelet-rich product obtained by centrifuging whole blood. PRP contains a large amount of growth factors, which have the effects of pain relief, wound healing, growth, and regeneration. High concentrations of platelets can alleviate cartilage degeneration, promote bone regeneration, and shorten the healing time of wounds and fractures. It is widely used in orthopedic and plastic surgery.

[0003] At present, since the liquid levels of the supernatant and platelets after centrifugation are relatively high in the separation device, platelets are easily extracted during the process of extracting the supernatant, resulting in problems of low extraction accuracy and low extraction efficiency.

[0004] Therefore, there is an urgent need for a platelet-rich plasma separation device with high extraction accuracy and high extraction efficiency. Utility Model Content

[0005] The purpose of the present application is to provide a platelet-rich plasma separation device to solve the problems of low extraction accuracy and low extraction efficiency existing in existing separation devices.

[0006] The embodiments of the present application can be implemented through the following technical solutions:

[0007] A platelet-rich plasma separation device comprises a cylinder, an upper cover and a piston. The upper cover is connected to the top of the cylinder and can be moved back and forth to the cylinder. The piston is accommodated in the cylinder and can be displaced along the axial direction of the cylinder.

[0008] The cylinder includes a chamber body and a partition. The chamber body is a hollow cylindrical structure, the upper part of which is connected to the upper cover, and the piston is accommodated inside. The partition is an inverted funnel-shaped structure, the top of which can abut against the upper cover, and the bottom of which is connected to the inner wall of the cylinder.

[0009] The top height of the partition is slightly lower than the top height of the side wall of the cylinder. The partition divides the warehouse into a first warehouse and a second warehouse that are interconnected. A channel is formed at the connection between the first warehouse and the second warehouse. The partition cooperates with the upper cover to realize the opening or closing of the channel.

[0010] Furthermore, the partition portion includes an extension portion and a transition portion, the extension portion is a cylindrical structure and extends along the axial direction of the cylinder, and the top end of the extension portion can abut against the upper cover; the transition portion is connected to an end of the extension portion away from the upper cover, and the extension portion is connected to the inner wall of the cylinder through the transition portion.

[0011] Furthermore, the first storage body is located on a side of the partition portion close to the piston.

[0012] Furthermore, the end surface of the transition portion facing the upper cover is a rounded structure, and the partition is made of a smooth material.

[0013] Furthermore, the extension portion and the transition portion are connected via a rounded portion, and the rounded portion is a rounded structure.

[0014] Preferably, the rounded portion has an angle of 6°, and the included angle between the transition portion and the inner wall of the second chamber body is 50°.

[0015] Furthermore, the separation device adopts a horizontal centrifugal method, the centrifugal force is lower than 400g, and the centrifugal time is 15 minutes.

[0016] Furthermore, the partition is made of a polycarbonate material, and a phosphorylcholine coating is provided on the surface of the partition.

[0017] Furthermore, the upper cover is provided with a first through hole and a second through hole, the first through hole is communicated with the first bin body, and the second through hole is communicated with the second bin body.

[0018] Furthermore, the volume of the second chamber is 17 ml or 23 ml.

[0019] The platelet-rich plasma separation device provided in the embodiments of the present application has at least the following beneficial effects:

[0020] (1) The separation device in the present application divides the chamber into a first chamber and a second chamber that are interconnected. A channel is formed at the connection between the first chamber and the second chamber. The upper cover cooperates with the partition to realize the opening or closing of the channel. The plasma completes the first centrifugation in the first chamber, and then the upper yellow part is pushed into the second chamber and completes the second centrifugation. The external extraction device extracts the upper white supernatant from the second chamber, and the remaining is PRP, which has the advantage of easy operation;

[0021] (2) The end surface of the transition part facing the upper cover in the present application is a rounded structure, and the partition is made of a smooth material. The rounded structure and the smooth material can achieve the aggregation of PRP, which can not only prevent the lower layer PRP from being drawn away while extracting the supernatant, but also prevent PRP from agglomerating into blocks, thereby improving the efficiency and accuracy of PRP extraction;

[0022] (3) The separation device in the present application uses horizontal centrifugation, the centrifugal force is less than 400g, the centrifugation time is 15 minutes, the platelets are stretched and deformed less, and the platelets can be guaranteed not to be activated during the preparation process to the greatest extent;

[0023] (4) The separation device in the present application realizes the preparation of PRP by two centrifugations, and the transfer process is completed in the separation device.

[0024] The PRP preparation process is completely isolated from the outside world, which fundamentally reduces the possibility of contamination and is easy to operate;

[0025] (5) The red blood cell stratification in the present application is convenient, which can reduce red blood cell contamination and reduce the loss of platelets. Therefore, when different personnel operate, the difference will not be too large, and the consistency of PRB quality can be better guaranteed. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 This is an overall structural diagram of a platelet-rich plasma separation device in this application;

[0027] Figure 2 is a cross-sectional view of a platelet-rich plasma separation device in the present application;

[0028] Figure 3 An exploded view of a platelet-rich plasma separation device in the present application;

[0029] Figure 4 This is the overall structural diagram of the piston in this application;

[0030] Figure 5 This is the overall structural diagram of the piston push rod in this application;

[0031] Figure 6 for Figure 2 A partial enlarged view of area A.

[0032] Figure numerals: 1. cylinder, 11. warehouse body, 111. first warehouse body, 112. second warehouse body, 12. partition portion, 121. extension portion, 122. transition portion, 123. smooth portion, 2. upper cover, 21. first through hole, 22. second through hole, 3. piston, 31. fitting groove, 4. piston push rod, 41. U-shaped groove, 42. protrusion. DETAILED DESCRIPTION

[0033] Hereinafter, the present application will be further described based on preferred embodiments with reference to the accompanying drawings.

[0034] The vocabulary in this specification is used to illustrate the embodiments of the present application, but is not intended to limit the present application. Unless otherwise clearly specified and limited, the terms "disposed", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, a direct connection, an indirect connection through an intermediate medium, or a communication between the two components. For those skilled in the art, the specific meanings of the above terms in this application can be specifically understood.

[0035] In addition, in the description of the embodiments of the present application, various components on the drawings are enlarged or reduced in size for ease of understanding, but this practice is not intended to limit the scope of protection of the present application.

[0036] The term "platelet-rich plasma (PRP)" used in this specification refers to a concentrate obtained by extracting platelets from autologous blood. When blood is centrifuged, the middle thin layer where platelets and white blood cells are concentrated is PRP, above it is a supernatant composed of a solution without blood cell particles, and below it is a red blood cell layer composed of a solution of red blood cell particles.

[0037] Figure 1-Figure 3 The overall structure diagram, cross-sectional diagram and exploded diagram of a platelet-rich plasma separation device in the present application are shown respectively. Figure 1-Figure 3 As shown, the separation device includes a cylinder 1, an upper cover 2 and a piston 3. The upper cover 2 is connected to the top of the cylinder 1 and can be connected to the cylinder 1 in an advance and retreat manner. The piston 3 is accommodated in the cylinder 1 and can be displaced along the axial direction of the cylinder 1.

[0038] Furthermore, the cylinder 1 includes a warehouse body 11 and a partition 12. The warehouse body 11 is a hollow cylindrical structure, which is connected to the upper cover 2 at the top and accommodates a piston 3 inside; the partition 12 is an inverted funnel-shaped structure, the top of which can abut against the upper cover 2, and the bottom end is connected to the inner wall of the cylinder 1. The partition 12 divides the warehouse body 11 into a first warehouse body 111 and a second warehouse body 112 that can be connected to each other. A channel is formed at the connection between the first warehouse body 111 and the second warehouse body 112. The upper cover 2 can move away from or approach the partition 12 along the axial direction of the cylinder 1, so that the opening or closing of the channel is achieved by the cooperation between the upper cover 2 and the partition 12, thereby controlling the connection or isolation between the first warehouse body 111 and the second warehouse body 112.

[0039] Furthermore, the height of the top of the partition 12 is slightly lower than the height of the top of the side wall of the cylinder 1 , so that the plasma in the first chamber 111 can pass over the top of the partition 12 and enter the second chamber 112 .

[0040] Furthermore, the partition 12 includes an extension portion 121 and a transition portion 122. The extension portion 121 is a cylindrical structure and extends along the axial direction of the cylinder 1. The top of the extension portion 121 can abut against the upper cover 2; the transition portion 122 is connected to the end of the extension portion 121 away from the upper cover 2, and the extension portion 121 is connected to the inner wall of the cylinder 1 through the transition portion 122, that is, the outer side of the transition portion 122 is connected to the interior of the cylinder 1.

[0041] Furthermore, the first chamber body 111 is located on a side of the partition portion 12 close to the piston 3, and the extension portion 121 and the first chamber body 111 form a narrow channel. When the piston 3 moves toward the upper cover 2, the plasma can pass through the narrow channel of the first chamber body 111, the channel between the first chamber body 111 and the second chamber body 112 and enter the second chamber body 112, thereby realizing the initial separation of the plasma.

[0042] After the plasma enters the second chamber 112, the separation device can be placed in a centrifuge for secondary centrifugation. At this time, the plasma in the second chamber 112 can be separated into supernatant and PRP. The supernatant is located at the top and can be extracted and separated by an extraction device.

[0043] However, if a common platelet-rich plasma separation device available on the market is used, due to the siphon effect of the liquid, the PRP in the lower layer is easily extracted while the supernatant is extracted. Therefore, in the present application, the end face of the transition portion 122 facing the upper cover 2 is a rounded structure, and the partition 12 is made of a smooth material. The rounded structure and the smooth material can be combined to achieve the aggregation of PRP, which can prevent the lower layer PRP from being extracted, and can also prevent the partition 12 and the second chamber 112 from aggregating the PRP into blocks, thereby improving the efficiency and accuracy of PRP extraction.

[0044] In some preferred embodiments of the present application, the partition 12 is made of a polycarbonate material, and a surface thereof is made of a phosphorylcholine coating material.

[0045] In some preferred embodiments of the present application, the cylinder 1 is spirally connected to the upper cover 2, and the outer periphery of the cylinder 1 is provided with an external thread that cooperates with the upper cover 2. Through the threaded connection, the connection between the cylinder 1 and the upper cover 2 is realized, and the upper cover 2 can be stably axially displaced along the cylinder 1, which is reliable and easy to process.

[0046] Therefore, when the upper cover 2 is tightened downward, the upper cover 2 abuts against the top of the extension part 121, and the first bin body 111 and the second bin body 112 are in a separated state; when the upper cover 2 is loosened upward, the upper cover 2 is separated from the top of the extension part 121, and the first bin body 111 and the second bin body 112 are in a connected state.

[0047] In some preferred embodiments of the present application, the partition 12 is coaxially arranged with the cylinder 1 to ensure the stability, accuracy and efficiency of plasma separation during the centrifugation of the cylinder 1.

[0048] Furthermore, a first through hole 21 and a second through hole 22 are formed in the upper cover 2 . The first through hole 21 is communicated with the first storage body 111 , and the second through hole 22 is communicated with the second storage body 112 .

[0049] Furthermore, a Luer connector is connected to the first through hole 21, and the first through hole 21 can be connected to a blood collection needle to introduce blood into the first bin body 111, and then the separation device is placed in a centrifuge for centrifugation once. At this time, the plasma in the first bin body 111 becomes a red-yellow junction after centrifugation, with the red color located at the bottom, and then the upper cover 2 is loosened upwards to separate the upper cover 2 from the extension portion 121, and then the piston 3 is pushed to move the plasma toward the upper cover 2, and the yellow plasma will enter the second bin body 112 through the narrow channel of the first bin body 111 until the red plasma is flush with the top of the extension portion 121; at this time, the upper cover 2 is tightened downwards to abut against the extension portion 121, and then the separation device is placed in a centrifuge for secondary centrifugation, and the external extraction device is connected to the second bin body 112 through the second through hole 22, and the external extraction device extracts the supernatant located at the top, and the remaining yellow part is the PRP to be produced.

[0050] In some preferred embodiments of the present application, a scale is provided on the second chamber body 112, and the user can extract a suitable volume of supernatant according to demand.

[0051] Specifically, the volume of the second chamber 112 is 17 ml and 23 ml.

[0052] In some preferred embodiments of the present application, the separation device further includes a piston push rod 4, which is connected to the side of the piston 3 away from the upper cover 2 and can drive the piston 3 to move along the axial direction of the first chamber 111. At the same time, when the separation device needs to be centrifuged, it is only necessary to separate the piston push rod 4 from the piston 3, and then put the separation device without the piston push rod 4 into the centrifuge.

[0053] Figure 4 , Figure 5 The overall structure diagrams of the piston 3 and the piston push rod 4 in the present application are shown respectively. Figure 4 and Figure 5 As shown, in some preferred embodiments of the present application, the rear end of the piston 3 is provided with an engaging groove 31, and the front end of the piston push rod 4 is provided with a U-shaped groove 41, so as to form an elastic spring sheet portion at the front end of the piston push rod 4, and the front end of the spring sheet portion is provided with a protrusion 42 that matches the engaging groove 31. When the spring sheet portion is pressed, the front end of the piston push rod 4 is deformed and can be easily removed from the piston 3.

[0054] In some specific embodiments of the present application, Figure 6 As shown, the extension portion 121 and the transition portion 122 are connected via a rounded portion 123 , and the rounded portion 123 is a rounded structure.

[0055] Furthermore, the angle α between the extension portion 121 and the transition portion 122, that is, the rounded angle reading α of the smooth portion 123, and the angle β between the transition portion 122 and the inner wall of the second chamber body 112, the effects of α and β on the platelet enrichment rate will be described in detail below.

[0056] In some preferred embodiments of the application, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 50°, the rounded angle reading α of the smooth portion 123 is 6°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be more than 1.8 times that of whole blood.

[0057] In comparative Example 1, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 40°, the rounded angle reading α of the smooth portion 123 is 1°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.67 times that of whole blood.

[0058] In comparative Example 2, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 45°, the rounded angle reading α of the smooth portion 123 is 1°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.64 times that of whole blood.

[0059] In comparative Example 3, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 55°, the rounded angle reading α of the smooth portion 123 is 1°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.4 times that of whole blood.

[0060] In comparative Example 4, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 60°, the rounded angle reading α of the smooth portion 123 is 1°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.3 times that of whole blood.

[0061] In comparative Example 5, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 40°, the rounded angle reading α of the smooth portion 123 is 3°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.77 times that of whole blood.

[0062] In comparative Example 6, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 45°, the rounded angle reading α of the smooth portion 123 is 3°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.74 times that of whole blood.

[0063] In comparative Example 7, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 55°, the rounded angle reading α of the smooth portion 123 is 3°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.5 times that of whole blood.

[0064] In comparative Example 8, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 60°, the rounded angle reading α of the smooth portion 123 is 3°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.4 times that of whole blood.

[0065] In comparative Example 9, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 40°, the rounded angle reading α of the smooth portion 123 is 6°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.8 times that of whole blood.

[0066] In comparative Example 10, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 45°, and the rounded angle reading α of the smooth portion 123 is 6°. After the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.8 times that of whole blood.

[0067] In comparative Example 11, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 55°, and the rounded angle reading α of the smooth portion 123 is 6°. After the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.6 times that of whole blood.

[0068] In comparative Example 12, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 60°, and the rounded angle reading α of the smooth portion 123 is 6°. After the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.5 times that of whole blood.

[0069] In comparative Example 13, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 40°, and the rounded angle reading α of the smooth portion 123 is 9°. After the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.8 times that of whole blood.

[0070] In comparative Example 14, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 45°, the rounded angle reading α of the smooth portion 123 is 9°, and after the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.8 times that of whole blood.

[0071] In comparative Example 15, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 55°, and the rounded angle reading α of the smooth portion 123 is 9°. After the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.6 times that of whole blood.

[0072] In comparative Example 16, the angle β between the transition portion 122 and the inner wall of the second chamber body 112 is 60°, and the rounded angle reading α of the smooth portion 123 is 9°. After the first centrifugation, the liquid in the second chamber body 112 is shaken evenly, and the enrichment rate in the second chamber body 112 is measured to be 1.5 times that of whole blood.

[0073] Furthermore, the angle β between the transition portion 122 and the inner wall of the second chamber 112 is 50°, and the rounded angle reading α of the smooth portion 123 is 6°. After the first centrifugation, the liquid in the second chamber 112 is shaken evenly, and the enrichment rate in the second chamber 112 is measured to be more than 1.8 times that of whole blood. The liquid in the second chamber 112 is centrifuged twice, the supernatant is extracted, and the remaining part is shaken evenly, and the platelet enrichment rate is measured to be 5-6 times that of whole blood.

[0074] In comparative Example 17, the inner wall of the second chamber 112 is uncoated, the liquid in the second chamber 112 is centrifuged twice, the supernatant is extracted, and the remaining portion is shaken evenly. Flocs are present in the second chamber 112, and platelets aggregate to form plaques. The platelet enrichment rate is measured to be 2-3 times that of whole blood.

[0075] As a comparative example 18, the inner wall of the second chamber 112 is coated with phosphorylcholine, the liquid in the second chamber 112 is centrifuged twice, the supernatant is extracted, and the remaining portion is shaken evenly, no flocs are produced in the second chamber 112, and the platelet enrichment rate is measured to be 5-6 times that of whole blood.

[0076] In some preferred embodiments of the present application, the separation device performs centrifugation by horizontal centrifugation, the centrifugal force is less than 400g, and the centrifugation time is 15 minutes. Under such centrifugal conditions, the platelets are less deformed by stretching, which can maximize the guarantee that the platelets are not activated during the preparation process, thereby further ensuring the efficiency and enrichment rate of PRP preparation.

[0077] The above is a detailed introduction to the specific implementation methods of the present application. For those skilled in the art, several improvements and modifications may be made to the present application without departing from the principles of the present application. These improvements and modifications also fall within the scope of protection of the claims of the present application.

Claims

1. A platelet-rich plasma separation device, comprising a barrel (1), an upper cover (2) and a piston (3), wherein the upper cover (2) is connected to the upper part of the barrel (1) and is connected to the barrel (1) in a retractable manner, and the piston (3) is accommodated in the barrel (1) and is displaceable in the axial direction of the barrel (1), characterized in that: The cylinder (1) comprises a chamber (11) and a partition (12); the chamber (11) is a hollow cylindrical structure, the upper part of which is connected to the upper cover (2), and the piston (3) is accommodated therein; the partition (12) is an inverted funnel-shaped structure, the top of which can abut against the upper cover (2), and the bottom of which is connected to the inner wall of the cylinder (1); The top height of the partition (12) is slightly lower than the top height of the side wall of the cylinder (1). The partition (12) divides the warehouse (11) into a first warehouse (111) and a second warehouse (112) which are interconnected. A passage is formed at the connection between the first warehouse (111) and the second warehouse (112). The partition (12) cooperates with the upper cover (2) to realize the opening or closing of the passage.

2. A platelet-rich plasma separation device according to claim 1, characterized in that: The partition portion (12) comprises an extension portion (121) and a transition portion (122); the extension portion (121) is a cylindrical structure and extends along the axial direction of the cylinder (1); the top end of the extension portion (121) can abut against the upper cover (2); the transition portion (122) is connected to an end of the extension portion (121) away from the upper cover (2); the extension portion (121) is connected to the inner wall of the cylinder (1) through the transition portion (122).

3. A platelet-rich plasma separation device according to claim 1, characterized in that: The first storage body (111) is located on a side of the partition (12) close to the piston (3).

4. A platelet-rich plasma separation device according to claim 2, characterized in that: The end surface of the transition portion (122) facing the upper cover (2) is a rounded structure, and the partition portion (12) is made of a smooth material.

5. A platelet-rich plasma separation device according to claim 4, characterized in that: The extension portion (121) and the transition portion (122) are connected via a smooth portion (123), and the smooth portion (123) is a rounded structure.

6. A platelet-rich plasma separation device according to claim 5, characterized in that: The rounded angle of the rounded portion (123) is 6°, and the included angle between the transition portion (122) and the inner wall of the second chamber body (112) is 50°.

7. A platelet-rich plasma separation device according to claim 4, characterized in that: The separation device adopts a horizontal centrifugal method, the centrifugal force is lower than 400g, and the centrifugal time is 15 minutes.

8. A platelet-rich plasma separation device according to claim 4, characterized in that: The partition (12) is made of a polycarbonate material, and a phosphorylcholine coating is provided on its surface.

9. A platelet-rich plasma separation device according to claim 1, characterized in that: The upper cover (2) is provided with a first through hole (21) and a second through hole (22); the first through hole (21) is communicated with the first bin body (111), and the second through hole (22) is communicated with the second bin body (112).

10. A platelet-rich plasma separation device according to claim 3, characterized in that: The volume of the second chamber (112) is 17ml and 23ml.

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