Sample detection card box

Abstract

The utility model relates to the technical field of sample detection, and discloses a sample detection card box which comprises a base and a sample adding cover. The sample adding cover covers the base in a sealing mode and is provided with a sample adding hole used for being communicated with the outside, the base is provided with a plurality of containing bins, the containing bins are used for being communicated with the sample adding cover in the rotating process, and a solution in the sample adding cover and sample treatment objects in the containing bins are mixed. A first rotating rail and a second rotating rail which extend in the circumferential direction are annularly arranged on the periphery of the base, and limiting bulges which are in sliding fit with the first rotating rail and the second rotating rail are also arranged on the sample adding cover. The limiting bulge positioned in the first rotating rail can drive the sample adding cover to rise to the isolation position, so that the phenomenon that the normal rotation of the sample adding cover is influenced due to interference between the sample adding hole and the storage bin is avoided. And a limiting bulge positioned in the second rotating rail can drive the sample adding cover to descend to a butt joint position, so that the sample adding hole is in tight butt joint with the storage bin, and the matching effect of the sample adding hole and the storage bin is improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of sample detection, and particularly relates to a sample detection cartridge. Background Art

[0002] The PCR technology is a molecular biology technology for amplifying a specific deoxyribonucleic acid sequence in vitro. Due to the characteristics of strong specificity, high sensitivity, low purity requirement, simplicity and rapidity of the PCR technology, it is widely used in nucleic acid detection and analysis. In order to achieve instant nucleic acid detection and improve the detection accuracy, various reagents need to be preset in a reagent kit, and the nucleic acid extraction and purification steps are realized by sucking, transferring and mixing the reagents multiple times. However, during the process of sample transfer, it is impossible to stably maintain at a fixed height, and there is a technical problem of unstable reagent transfer. Summary of the Utility Model

[0003] The purpose of the utility model is to provide a sample detection cartridge, which can solve the technical problem of unstable reagent transfer.

[0004] In order to achieve the above purpose, the utility model provides a sample detection cartridge, which includes:

[0005] A base, which is provided with a plurality of storage bins. Along the axial direction, a first rotating track and a second rotating track are arranged at intervals on the base, and both the first rotating track and the second rotating track are annularly arranged on the outer periphery of the base;

[0006] A sampling cover, which is hermetically covered on the base and is provided with a sampling hole for communicating with the outside. The plurality of storage bins are used for communicating with the sampling cover during rotation. The sampling cover is further provided with limiting protrusions that are in sliding contact and cooperation with the first rotating track and the second rotating track. The limiting protrusions located in the first rotating track can drive the sampling cover to rise to an isolation position, so that the sampling hole and the storage bin are isolated from each other. The limiting protrusions located in the second rotating track can drive the sampling cover to descend to a docking position, so that the sampling hole and the storage bin are docked.

[0007] In an embodiment of the utility model, the first rotating track and the second rotating track are isolated by a protrusion part. The protrusion part extends circumferentially along the outer periphery of the base and is provided with an adjustment notch for the limiting protrusion to pass through.

[0008] In an embodiment of the utility model, the protrusion part includes a long protrusion and a short protrusion, and the long protrusion and the short protrusion are arranged at equal intervals.

[0009] In an embodiment of the utility model, the number of the long protrusions and the short protrusions is multiple, and an adjustment notch is formed between any adjacent long protrusion or short protrusion, and the adjustment notch corresponds to the storage bin.

[0010] In an embodiment of the present utility model, along the height direction of the base, a vertical limiting groove is correspondingly arranged above the adjustment notch. The vertical limiting groove is for the limiting protrusion to slide and adjust along the height direction of the base, and the number of vertical limiting grooves is multiple and is arranged corresponding to the adjustment notch one by one.

[0011] In an embodiment of the present utility model, a guiding inclined surface is formed on one side of the limiting protrusion facing the base. The guiding inclined surface is inclined from the side close to the base towards the inner side wall of the sampling cover. The guiding inclined surface is used for guiding cooperation with the first rotating rail, the second rotating rail and the vertical limiting groove.

[0012] In an embodiment of the present utility model, a movable groove is further opened on the sampling cover. The movable groove is arranged corresponding to the limiting protrusion and is arranged in a semi-enclosing manner with the limiting protrusion.

[0013] In an embodiment of the present utility model, a magnetic bead groove for containing magnetic beads is further arranged on the base, and a magnetic attracting member for adsorbing magnetic beads is arranged on the sampling cover. The sampling cover is used for rotating in the isolation position and driving the magnetic beads to be docked with the storage bin. The sampling cover is used for adsorbing magnetic beads by the magnetic attracting member in the docking position. The sampling cover is further used for rotating in the docking position and separating the magnetic attracting member from the magnetic beads.

[0014] In an embodiment of the present utility model, a magnetic attracting hole is arranged on one side of the sampling cover facing the base, and the magnetic attracting member is sealed in the magnetic attracting hole.

[0015] In an embodiment of the present utility model, a liquid transfer hole is further opened on one side of the sampling cover facing the base. One end of the liquid transfer hole is open and is used for communicating with the storage bin.

[0016] By the above technical solutions, the sample detection cartridge provided by the embodiment of the present utility model has the following beneficial effects:

[0017] The sample detection cartridge in this embodiment includes a base and a sampling cover. The sampling cover is hermetically covered on the base and is provided with a sampling hole for communicating with the outside. A plurality of storage bins are arranged on the base. The plurality of storage bins are used for communicating with the rotating sampling cover and mixing the solution in the sampling cover with the sample treatment substances in the storage bins. A first rotating rail and a second rotating rail are arranged circumferentially on the base. Both the first rotating rail and the second rotating rail are arranged around the outer periphery of the base. The sampling cover is further provided with a limiting protrusion that slidably cooperates with the first rotating rail and the second rotating rail. The limiting protrusion located in the first rotating rail can drive the sampling cover to rise to the isolation position to avoid interference between the sampling hole and the storage bin and affect the normal rotation of the sampling cover. The limiting protrusion located in the second rotating rail can drive the sampling cover to descend to the docking position, so that the sampling hole is closely docked with the storage bin, improving the matching effect between the sampling hole and the storage bin. The position switching in the height direction can be realized by simply rotating the sampling cover, and the reagent can be stably transferred to avoid reagent cross-contamination.

[0018] Other features and advantages of the embodiments of the present utility model will be described in detail in the subsequent specific embodiments section. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The drawings are used to provide a further understanding of the embodiments of the present utility model, and constitute a part of the specification. Together with the following specific embodiments, they are used to explain the embodiments of the present utility model, but do not constitute a limitation to the embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on the structures shown in these drawings. In the drawings:

[0020] Figure 1 is a schematic structural diagram of a sample detection cartridge according to the present utility model;

[0021] Figure 2 is a schematic structural diagram of a sample addition cover from one perspective according to the present utility model;

[0022] Figure 3 is a schematic structural diagram of the sample addition cover from another perspective according to the present utility model;

[0023] Figure 4 is a schematic structural diagram of a base from one perspective according to the present utility model;

[0024] Figure 5 is a schematic structural diagram of the base from another perspective according to the present utility model.

[0025] DESCRIPTION OF THE REFERENCE NUMERALS

[0026] 1 Base 2 Sample addition cover

[0027] 11 Storage bin 21 Sample addition hole

[0028] 12 First rotating track 22 Limiting protrusion

[0029] 13 Second rotating track 23 Moving slot

[0030] 14 Adjusting notch 24 Magnetic attraction hole

[0031] 15 Vertical limiting slot 25 Pipetting hole

[0032] 16 Placing limiting slot 26 Rotating protrusion

[0033] 17 Rotating limiting slot 27 Buckle

[0034] 18 In-place limiting slot 28 Movement card slot

[0035] 19 Protruding part 3 Hole cover

[0036] 191 Short protrusion 4 gasket

[0037] 192 Long protrusion Specific implementation manner

[0038] The specific implementation manner of the present utility model will be described in detail below with reference to the accompanying drawings. It should be understood that the specific implementation manner described here is only used to illustrate and explain the present utility model, and is not used to limit the present utility model.

[0039] The sample detection cartridge according to the present utility model will be described below with reference to the accompanying drawings.

[0040] As Figure 1 and Figure 4 shown, in this embodiment, a sample detection cartridge is proposed. The sample detection cartridge includes a base 1 and a sampling cover 2. A plurality of storage bins 11 are formed on the base 1. The first rotating rail 12 and the second rotating rail 13 are arranged at intervals along the axial direction on the base 1. Both the first rotating rail 12 and the second rotating rail 13 are disposed around the outer periphery of the base 1. The sampling cover 2 is hermetically covered on the base 1 and is provided with a sampling hole 21 for communicating with the outside. The plurality of storage bins 11 are used to communicate with the sampling cover 2 during rotation. The sampling cover 2 is further provided with a limiting protrusion 22 that slidably contacts and cooperates with the first rotating rail 12 and the second rotating rail 13. The limiting protrusion 22 located in the first rotating rail 12 can drive the sampling cover 2 to rise to the isolation position, so that the sampling hole 21 and the storage bin 11 are isolated from each other. The limiting protrusion 22 located in the second rotating rail 13 can drive the sampling cover 2 to descend to the docking position, so that the sampling hole 21 and the storage bin 11 are docked.

[0041] The sample detection cartridge in this embodiment includes a base 1 and a sampling cover 2. The sampling cover 2 is hermetically closed on the base 1 and is provided with a sampling hole 21 for communicating with the outside. The base 1 is provided with a plurality of storage bins 11, and the plurality of storage bins 11 are used to communicate with the sampling cover 2 during rotation, so that the solution in the sampling cover 2 is mixed with the sample treatment substance in the storage bin 11. A first rotating track 12 and a second rotating track 13 are arranged circumferentially on the base 1. Both the first rotating track 12 and the second rotating track 13 are provided around the outer periphery of the base 1. The sampling cover 2 is further provided with a limiting protrusion 22 that slidably cooperates with the first rotating track 12 and the second rotating track 13. The limiting protrusion 22 located in the first rotating track 12 can drive the sampling cover 2 to rise to the isolation position to avoid interference between the sampling hole 21 and the storage bin 11 and affect the normal rotation of the sampling cover 2. The limiting protrusion 22 located in the second rotating track 13 can drive the sampling cover 2 to descend to the docking position, closely docking the sampling hole 21 with the storage bin 11, improving the matching effect between the sampling hole 21 and the storage bin 11. The position switching in the height direction can be realized by simply rotating the sampling cover 2. Compared with the detection cartridges in the prior art, the reagent can be transferred more stably, and cross-contamination of the reagent can be avoided. Among them, a card hole is further provided at the central position of the base 1. Preferably, the plurality of storage bins 11 are arranged around the outer periphery of the card hole. A buckle 27 passing through the card hole is provided on the top cover. The buckle 27 is hermetically cooperated with the card hole through a sealing member, improving the sealing effect of the sample detection cartridge and also improving the connection stability between the sampling cover 2 and the base 1. Among them, the sampling cover 2 is made of an injection molding material.

[0042] As Figure 4 shown, in this embodiment, the first rotating track 12 and the second rotating track 13 are isolated by a protrusion 19. The protrusion 19 extends circumferentially along the outer periphery of the base 1 and is provided with an adjustment notch 14 for the limiting protrusion 22 to pass through, so that the limiting protrusion 22 can stably slide along the first rotating track 12 or the second rotating track 13 under the restriction of the protrusion 19, improving the stability of the cooperation between the limiting protrusion 22 and the first rotating track 12 or the second rotating track 13.

[0043] As Figure 3 shown, the protrusion 19 includes a long protrusion 192 and a short protrusion 191, and the long protrusion 192 and the short protrusion 191 are arranged at equal intervals. In this embodiment, the number of both the short protrusion 191 and the long protrusion 192 is two. The lengths of the short protrusions 191 are the same, while the lengths of the long protrusions 192 are different. The number and length of the long protrusions 192 and the short protrusions 191 can be set according to actual needs.

[0044] In this embodiment, the number of the long protrusions 192 and the short protrusions 191 is multiple. An adjustment notch 14 is formed between any adjacent long protrusions 192 or short protrusions, and the adjustment notch 14 is arranged corresponding to the storage bin 11. The setting of the adjustment notch 14 depends on whether the storage bin 11 on the base 1 needs to cooperate with the magnetic part. If it needs to cooperate with the magnetic part, an adjustment notch 14 is formed at the position corresponding to the storage bin 11. By flipping the sample detection cartridge, the magnetic beads are adsorbed on the magnetic part, and then the sample detection cartridge is flipped again to drive the sampling cover 2 to switch from the docking position to the isolation position. At this time, the magnetic beads can be transferred to other storage bins 11 as the sampling cover 2 rotates. If the storage bin 11 on the base 1 does not need to cooperate with the magnetic part, no adjustment notch 14 is provided on the protrusion 19 at the position corresponding to the storage bin 11.

[0045] As Figure 4 shown, in this embodiment, a vertical limiting groove 15 is arranged above the adjustment notch 14 along the height direction of the base 1. The vertical limiting groove 15 is for the limiting protrusion 22 to slide and adjust along the height direction. The number of the vertical limiting grooves 15 is multiple and is arranged corresponding to the adjustment notch 14 one by one. The setting of the vertical limiting groove 15 enables the sampling cover 2 to have a wider adjustment range in the height direction and plays a role in pre-guiding the limiting protrusion 22 during the assembly of the sampling cover 2 and the base 1.

[0046] As Figure 4 shown, in this embodiment, the sample detection cartridge further includes a sealing gasket 4. The sealing gasket 4 covers the base 1 and is provided with avoidance notches corresponding to the card holes and the storage bins 11. Preferably, the sealing gasket 4 can be integrally formed with the base 1, and the connection effect is good. The sealing gasket 4 is made of rubber or silica gel and has a certain deformation ability, so that the docking and sealing effect between the liquid transfer hole 25 and the storage bin 11 is better, and the spillage of the sample treatment substance caused by the imperfect docking between the liquid transfer hole 25 and the storage bin 11 is avoided.

[0047] In this embodiment, the sample detection cartridge further includes a sampling sealing ring arranged on the sampling cover 2. The sampling sealing ring is coaxially arranged with the sampling hole 21. A hole cover 3 is also covered on the sampling hole 21. The hole cover 3 extending into the sampling hole 21 is in sealing cooperation with the sampling hole 21 through the sampling sealing ring, further improving the sealing performance of the sample detection cartridge and ensuring that during the nucleic acid detection process, external pollutants do not enter the interior of the sample detection cartridge from the sampling hole 21. Among them, the sampling sealing rings all adopt rubber sealing rings in the prior art.

[0048] In this embodiment, a guiding inclined surface is formed on the side of the limiting protrusion 22 facing the base 1. The guiding inclined surface is arranged to incline from the side close to the base 1 towards the inner side wall of the sampling cover 2. The guiding inclined surface is used for guiding cooperation with the first rotating track 12, the second rotating track 13 and the vertical limiting groove 15, so that the limiting protrusion 22 can slide more smoothly in the first rotating track 12 or the second rotating track 13, and the sliding adjustment along the adjustment notch 14 into the vertical limiting groove 15 is more fluent, improving the fluency of the rotation and vertical adjustment of the sampling cover 2 relative to the base 1. Among them, the width of the limiting protrusion 22 is the same as that of the vertical limiting groove 15 and the adjustment notch 14, avoiding the shaking of the sampling cover 2 caused by the loose fit between the limiting protrusion 22 and the vertical limiting groove 15, which affects the docking cooperation between the magnetic component and the storage bin 11.

[0049] As Figure 2 shown, in this embodiment, a movable groove 23 is further formed on the sampling cover 2. The movable groove 23 is arranged corresponding to the limiting protrusion 22 and is semi-enclosed with the limiting protrusion 22. The movable groove 23 is arranged in a U shape, so that the limiting protrusion 22 has a certain deformation adjustment range, reducing the resistance during the assembly process of the sampling cover 2 and the base 1, and facilitating the assembly and cooperation between the sampling cover 2 and the base 1. Of course, the movable groove 23 can also adopt other structural forms as long as it has a certain deformation adjustment range.

[0050] In an embodiment, no protrusion 19 is provided on the sample detection device. A magnetic bead groove for containing magnetic beads is further provided on the base 1. A magnetic component for adsorbing magnetic beads is provided on the sampling cover 2. The sampling cover 2 is used to rotate in the isolation position and drive the magnetic beads to dock with the storage bin 11. The sampling cover 2 is used to adsorb the magnetic beads through the magnetic component in the docking position. The sampling cover 2 is also used to rotate in the docking position and separate the magnetic component from the magnetic beads. Among them, a magnetic bead hole for accommodating magnetic beads is further provided on the base 1. First, rotate the sampling cover 2 to align the sampling hole 21 with the magnetic bead hole, inject nucleic acid substances, and then rotate the sampling cover 2 to adsorb the magnetic beads through the magnetic component. The nucleic acid substances are attached to the magnetic beads. Then drive the sampling cover 2 to rotate axially to align the sampling hole 21 with the storage bin 11, adsorb the magnetic beads by using the magnetic component, and then continue to rotate the sampling cover 2 to realize the transfer of nucleic acid substances, so that the nucleic acid substances are transported through the magnetic component and react with the reagents in multiple storage bins 11 on the base 1 in sequence, and finally complete the detection of nucleic acid substances. Among them, the magnetic component is a magnet in the prior art.

[0051] In another embodiment, a protrusion 19 is provided on the sample detection device, and a magnetic hole 24 is provided on the side of the sample cover 2 facing the base 1, and the magnetic suction component is sealed in the magnetic suction hole 24, and the magnetic suction hole 24 does not pass through the sample cover 2. Preferably, the diameter of the magnetic suction component is slightly smaller than the aperture of the magnetic suction hole 24, and a filling gap is left between the magnetic suction component and the magnetic suction hole 24, and the filling gap can be used for the injection of sealant, thereby, the magnetic suction component is fixed in the magnetic suction hole 24 by the sealant, ensuring the connection stability of the magnetic suction component. Of course, the magnetic suction component can also be fixed in the magnetic suction hole 24 by interference fit, and other methods that can fix the magnetic suction component are also possible. Among them, the diameter of the magnetic suction component matches the diameter of the storage bin 11.

[0052] When it is necessary to transfer the magnetic beads, first drive the sample cover 2 to adjust downward in the height direction, and the limiting protrusion 22 is switched from the first rotating rail 12 to the second rotating rail 13 through the adjustment notch 14. At this time, the magnetic suction piece on the sample cover 2 is docked with the storage bin 11 on the base 1, and the sealing effect is good and it is not easy to leak the reagent. Then, by flipping the sample test card box, the magnetic beads in the storage bin 11 are adsorbed on the magnetic suction piece, and the sample test card box is flipped again. At this time, the notch 14 can be adjusted and the second rotating rail 13 can be switched to the first rotating rail 12, and then the sample cover 2 is driven to rotate, and the magnetic suction piece can be docked to other storage bins 11. Drive the sample cover 2 to adjust downward in the height direction again, so that the magnetic suction piece docks with the storage bin 11, and then rotate the sample cover 2 again, and the magnetic beads can be retained in the storage bin 11.

[0053] In one embodiment, a moving card slot 28 is provided at the top of the sample loading cover 2, and the moving card slot 28 penetrates the sample loading cover 2 radially. An opening for the sample mixing device to extend into is provided on the side of the moving card slot 28 away from the base 1, and the opening of the moving card slot 28 also extends radially along the sample loading cover 2. This arrangement can increase the length for the sample mixing device to extend into, and enhance the adaptability to the sample mixing device. Among them, the moving card slot 28 extends radially and has a large contact area, which is convenient for the sample mixing device to fully contact the moving card slot 28 after entering the moving card slot 28, thereby improving the stability of the sample mixing device and the moving card slot 28. In addition, the moving card slot 28 is arranged at the top of the sample loading cover 2, which is convenient for the connection operation of the sample mixing device, and can effectively improve the operating efficiency of reagent mixing.

[0054] In another embodiment, the opening of the motion slot 28 on the side away from the base 1 does not extend radially along the sample loading cover 2, and the sample mixing device can be inserted into the motion slot 28 through the openings at both ends of the motion slot 28 along the radial direction, and then the locking piece is inserted into the opening, and the sample mixing device is fixed by the locking piece, thereby improving the stability of the adapter connection between the sample mixing device and the motion slot 28.

[0055] like Figure 3As shown, in this embodiment, a pipetting hole 25 is further formed on one side of the sampling cover 2 facing the base 1. One end of the pipetting hole 25 is open and used to receive and accommodate the storage bin 11. Similarly, the pipetting hole 25 does not penetrate through the sampling cover 2. The pipetting hole 25 is used to transfer the liquid in the storage bin 11. After the pipetting hole 25 is docked with the storage bin 11, the sample detection cartridge is flipped by the sample mixing device. At this time, the base 1 is above the sampling cover 2, so that the liquid in the storage bin 11 flows into the pipetting hole 25. At this time, the sample mixing device drives the sampling cover 2 to rotate relative to the cartridge until it is docked with another storage bin 11. After the liquids in all the storage bins 11 are mixed in sequence, the sample detection cartridge is flipped by the sample mixing device again. At this time, the sampling cover 2 is above the base 1. Of course, the sample detection cartridge can be flipped multiple times during the mixing process of the liquid in the storage bin 11 and the pipetting hole 25 to ensure that the liquids in the storage bin 11 and the pipetting hole 25 can be fully mixed.

[0056] As Figure 2 and Figure 3 shown, the centers of the pipetting hole 25, the sampling hole 21, and the magnetic attraction hole 24 on the sampling cover 2 are located on the same radius arc. Preferably, the pipetting hole 25, the sampling hole 21, and the magnetic attraction hole 24 are arranged circumferentially on the sampling cover 2 and are arranged around the outer circumference of the buckle 27. The sampling hole 21 is arranged between the magnetic attraction hole 24 and the pipetting hole 25. The docking of the pipetting hole 25, the sampling hole 21, and the magnetic attraction hole 24 with the storage bin 11 on the base 1 can be achieved only by rotating operations. Other arrangement methods of the pipetting hole 25, the sampling hole 21, and the magnetic attraction hole 24 can also be adjusted accordingly according to the arrangement of the magnetic bead holes and the storage bins 11 on the base 1. Moreover, the distance between the magnetic attraction hole 24 and the pipetting hole 25 is correspondingly set according to the distance between different storage bins 11 on the base 1. The distance between the sampling hole 21 and the magnetic attraction hole 24 can also be adjusted according to the distance between the magnetic bead holes and the storage bins 11 on the base 1.

[0057] Among them, a limiting protrusion 22 is further formed on the side wall surface of the sampling cover 2. The limiting protrusion 22 is arranged corresponding to the magnetic attraction hole 24. The limiting protrusion 22, the magnetic attraction hole 24, and the center of the sampling cover 2 are located on the same straight line. The limiting protrusion 22 is used for sliding contact and cooperation with the rotation track formed on the side wall of the base 1, so as to facilitate the sampling cover 2 to rotate more stably relative to the base 1 under the drive of the sample mixing device. An in-place limiting groove 18 is also formed on the base 1, which can effectively determine the in-place situation of the sample detection cartridge placed on the external adjustment instrument. Further, a placement limiting groove 16 is formed at the bottom of the base 1. The placement limiting groove 16 extends along the radial direction of the base 1 and the sizes of the placement openings arranged at both ends of the placement limiting groove 16 along the radial direction are different, which can assist in determining whether the placement position of the sample detection cartridge is correct.

[0058] As Figure 1 and Figure 2As shown in the figure, in this embodiment, the moving card slot is provided in the middle of the sampling cover 2 and divides the sampling cover 2 into two top cover parts with the same shape. The pipetting hole 25, the sampling hole 21, and the magnetic attraction hole 24 are all arranged on the top cover part on any one side of the moving card slot 28. The layout is compact, improving the space utilization rate of the sampling cover 2. Among them, a rotation limit groove 17 is also provided on the base 1, and a rotation protrusion 26 is formed on the side wall of the sampling cover 2. The rotation protrusion 26 is used to cooperate with the rotation limit groove 17, and a notch is provided above the rotation protrusion 26 for the elastic deformation of the rotation protrusion 26, so as to better cooperate with the rotation limit groove 17, making it difficult for the rotation protrusion 26 to slide after being engaged with the rotation limit groove 17, and effectively restricting the technical problem that the sampling cover 2 of the sample detection cartridge is prone to rotate relative to the base 1 after leaving the factory.

[0059] In the description of the present invention, it should be understood that the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one of these features. In the description of the present invention, the meaning of "a plurality" is at least two, such as two, three, etc., unless otherwise specifically defined.

[0060] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed", etc. should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or integrated; it can be a mechanical connection, an electrical connection, or communication with each other; it can be directly connected, or indirectly connected through an intermediate medium, and can be the internal communication of two components or the interaction relationship between two components, unless otherwise clearly limited. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0061] In the description of this specification, the description with reference to terms such as "one embodiment", "some embodiments", "example", "specific example", or "some examples" means that the specific features, structures, materials, or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic expressions of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described can be combined in a suitable manner in any one or more embodiments or examples. In addition, without contradiction, those skilled in the art can combine and combine the different embodiments or examples described in this specification and the features of different embodiments or examples.

[0062] Although the embodiments of the present utility model have been shown and described above, it can be understood that the above embodiments are exemplary and should not be construed as limiting the present utility model. Those of ordinary skill in the art can make changes, modifications, substitutions, and variations to the above embodiments within the scope of the present utility model.

Claims

1. A sample detection cartridge, characterized in that: The sample detection cartridge comprises: A base (1) is provided with a plurality of storage bins (11), a first rotating rail (12) and a second rotating rail (13) are arranged on the base (1) at intervals along the axial direction, and the first rotating rail (12) and the second rotating rail (13) are both arranged around the outer periphery of the base (1); A sample loading cover (2) is covered on the base (1) and is provided with a sample loading hole (21) for communicating with the outside. The plurality of storage bins (11) are used to communicate with the sample loading cover (2) during the rotation process. The sample loading cover (2) is also provided with a limiting protrusion (22) that is in sliding contact with the first rotating rail (12) and the second rotating rail (13). The limiting protrusion (22) located in the first rotating rail (12) can drive the sample loading cover (2) to rise to an isolation position so that the sample loading hole (21) and the storage bin (11) are isolated from each other. The limiting protrusion (22) located in the second rotating rail (13) can drive the sample loading cover (2) to fall to a docking position so that the sample loading hole (21) and the storage bin (11) are docked.

2. The sample detection cartridge according to claim 1, characterized in that: The first rotating rail (12) and the second rotating rail (13) are separated by a protrusion (19), and the protrusion (19) extends along the circumference of the outer periphery of the base (1) and is provided with an adjustment notch (14) for the limiting protrusion (22) to pass through.

3. The sample detection cartridge according to claim 2, characterized in that: The protrusion (19) comprises a long protrusion (192) and a short protrusion (191), and the long protrusion (192) and the short protrusion (191) are arranged at equal intervals.

4. The sample detection cartridge according to claim 3, characterized in that: The number of the long protrusions (192) and the short protrusions (191) is plural, and the adjustment notch (14) is formed between any adjacent long protrusions (192) or short protrusions, and the adjustment notch (14) is arranged corresponding to the storage bin (11).

5. The sample detection cartridge according to claim 4, characterized in that: Along the seat height direction of the base (1), a vertical limit groove (15) is arranged above the adjustment notch (14) in correspondence, and the vertical limit groove (15) allows the limit protrusion (22) to slide and adjust along the seat height direction. The number of the vertical limit grooves (15) is multiple and they are arranged one by one corresponding to the adjustment notches (14).

6. The sample detection cartridge according to claim 5, characterized in that: A guiding slope is formed on one side of the limiting protrusion (22) facing the base (1), and the guiding slope is arranged obliquely from the side close to the base (1) toward the inner side wall of the sample loading cover (2), and the guiding slope is used for guiding and cooperating with the first rotating rail (12), the second rotating rail (13) and the vertical limiting groove (15).

7. The sample detection cartridge according to any one of claims 1 to 6, characterized in that: The sample loading cover (2) is also provided with a movable groove (23), and the movable groove (23) is arranged corresponding to the limiting protrusion (22) and is semi-enclosed with the limiting protrusion (22).

8. The sample detection cartridge according to any one of claims 1 to 6, characterized in that: The base (1) is also provided with a magnetic bead groove for containing magnetic beads, the sample loading cover (2) is provided with a magnetic suction piece for adsorbing magnetic beads, the sample loading cover (2) is used to rotate in the isolation position and drive the magnetic beads to dock with the storage bin (11), the sample loading cover (2) is used to adsorb the magnetic beads through the magnetic suction piece in the docking position, and the sample loading cover (2) is also used to rotate in the docking position and separate the magnetic suction piece from the magnetic beads.

9. The sample detection cartridge according to claim 8, characterized in that: A magnetic attraction hole (24) is provided on one side of the sample loading cover (2) facing the base (1), and the magnetic attraction component is sealed in the magnetic attraction hole (24).

10. The sample detection cartridge according to any one of claims 1 to 6, characterized in that: The sample loading cover (2) is also provided with a transfer hole (25) on one side facing the base (1); one end of the transfer hole (25) is open and is used to connect with the storage bin (11).

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