Cleaning station for reaction cup
By using a combination of megasonic cleaning unit and flushing unit in the analyzer, the problem that traditional cleaning methods are difficult to completely remove latex particles in the inner wall of the reaction cup is solved, and a more efficient cleaning effect is achieved, the service life of the reaction cup is extended, and the accuracy of the analysis results is ensured.
Patent Information
- Application Number
- CN202421731859.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-19
- Publication Date
- 2025-06-10
- Estimated Expiration
- 2034-07-19
AI Technical Summary
The cleaning method of traditional analyzers is difficult to thoroughly clean the latex particles attached to the inner wall of the reaction cup, resulting in a decrease in the light transmittance of the reaction cup and affecting the accuracy of the analysis results.
Using a method of combining a megasonic cleaning unit and a rinsing unit, the megasonic cleaning unit peels off the latex particles on the wall of the reaction cup through an ultrasonic generator, transducer and reflection baffle. The rinsing unit further rinses and removes the latex particles through a liquid aspiration needle and a liquid injection needle.
It effectively removes latex particles attached to the inner wall of the reaction cup, extends the service life or maintenance cycle of the reaction cup, reduces the user's cost, and ensures the accuracy of the analysis results.
Smart Images

Figure CN222957131U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of biochemical analyzers, and specifically relates to a cleaning station for reaction cups. Background Art
[0002] Reaction vessels of instruments such as automatic biochemical analyzers and specific protein analyzers. Among them, the reaction cups of automatic biochemical analyzers are generally called colorimetric cups or reaction cups, and the reaction cups of automatic specific protein analyzers are generally called reaction cups. In this article, they are collectively referred to as reaction cups; the surface finish of the inner wall of the reaction cup is between Ra 0.05 and Ra 0.1. Under microscopic conditions, the surface of the inner wall of the reaction cup is actually uneven; there are latex particles in the reagents for immunoturbidimetry assays. The diameter of the latex particles is generally between 80nm and 300nm. The latex particles are easily adsorbed on the surface of the inner wall of the reaction cup during the test. The traditional cleaning method of the analyzer uses cleaning liquid and water to dilute, rinse, and flush the surface of the reaction cup; and conventional ultrasonic cleaning is used in combination, but it is difficult to clean thoroughly.
[0003] Moreover, after the analyzer performs immunoturbidimetry assays, after a period of time, the inner wall surface of the reaction cup (colorimetric cup) will show a white mist; this affects the light transmittance of the reaction cup and leads to inaccurate results.
[0004] For reaction cups with a white mist on the inner wall: reaction cups made of plastic need to be replaced with new ones, and reaction cups made of quartz or glass need to be manually maintained; the user's cost is high, time-consuming and laborious, and the results of the analysis system are not guaranteed. Therefore, it is necessary to make improvements. Content of the Utility Model
[0005] In order to solve the above problems of the prior art, the utility model provides a cleaning station for reaction cups, which has good cleaning effect, saves costs, and ensures accurate analysis results of the analyzer.
[0006] To achieve the above object, the utility model adopts the following technical solutions:
[0007] As one aspect of the utility model, a cleaning station for reaction cups is proposed, which includes: a megasonic cleaning unit and a flushing unit. The megasonic cleaning unit is used to peel off the latex particles attached to the wall of the reaction cup; the flushing unit flushes the peeled-off latex particles.
[0008] The megasonic cleaning unit includes more than one ultrasonic generator, transducer and reflection baffle. The ultrasonic generator is electrically connected to the transducer. The reflection baffle is arranged on the side of the transducer. A reaction cup channel is formed between the reflection baffle and the transducer. The transducer and the reflection baffle are both located on the water bath tank. The transducer and the reflection baffle are respectively located on both sides of the reaction cup channel; the reaction cup is connected to the reaction cup rack.
[0009] The rinsing unit includes a liquid suction needle, and liquid injection needles are respectively arranged on both sides of the liquid suction needle. The liquid outlet of the liquid injection needle is higher than that of the liquid suction needle; the liquid outlet of the liquid injection needle forms a 45-degree angle with the center line of the liquid suction needle. The operation of the rinsing unit is divided into two sections: a downward movement and an upward movement. During the downward movement, the liquid suction needle sucks dry the liquid in the reaction cup, and during the upward movement, liquid is injected into the reaction cup while sucking away the liquid.
[0010] Optionally, the ultrasonic generator includes a front-section ultrasonic generator, a middle-section ultrasonic generator, a rear-section ultrasonic generator, and an end ultrasonic generator that are sequentially arranged at intervals from top to bottom.
[0011] Optionally, a limiting groove is provided on the reaction cup holder, and the elastic piece of the reaction cup is matched with the limiting groove.
[0012] Optionally, a reaction cup support is provided on the reaction cup holder.
[0013] Optionally, the vibration frequency of the transducer is 0.8 MHz to 1.65 MHz.
[0014] Optionally, the material of the reflection baffle is stainless steel.
[0015] Optionally, the megasonic cleaning unit further includes a base, and the ultrasonic generator is connected to the base; a reaction cup channel is formed on the base, and the transducer and the reflection baffle are respectively connected to the base; the base is connected to the water bath through a connecting piece, and the transducer and the reflection baffle are located in the water bath.
[0016] Optionally, the two liquid injection needles are symmetrically arranged with respect to the center line of the liquid suction needle.
[0017] Optionally, the liquid suction needle and the liquid injection needle are integrally formed by packing. The integrated liquid suction needle and liquid injection needle are connected to an outer tube, and a fixing plate is connected to the outer tube.
[0018] Optionally, a lifting unit is further included. The lifting unit includes a base and a lifting seat. The base is connected to the water bath; the lifting seat is slidably connected to the base and can move up and down on the base; a lifting motor is connected to the base, and the output end of the lifting motor is connected to the lifting seat. The rinsing unit is connected to the lifting seat, and the rinsing unit is connected to the lifting seat through a fixing plate.
[0019] The cleaning station for the reaction cup of the present utility model has the following beneficial effects, which are specifically reflected in: by cooperating the megasonic cleaning unit and the flushing unit, the liquid with suspended latex particles is sucked dry and cleaning liquid and purified water are injected; thereby realizing the cleaning of the latex particles attached to the surface of the cup wall of the reaction cup, avoiding the attachment of latex particles on the surface of the reaction cup; extending the service life of the semi-permanent reaction cup (made of plastic) or extending the maintenance cycle of the permanent reaction cup (made of glass or quartz), saving the user's instrument usage cost, and ensuring the accuracy of the instrument analysis results. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] The accompanying drawings forming a part of this application are used to provide a further understanding of the present utility model. The schematic embodiments of the present utility model and their descriptions are used to explain the present utility model and do not constitute an improper limitation to the present utility model.
[0021] Figure 1 It is a schematic structural diagram of the cleaning station for the reaction cup of the present utility model;
[0022] Figure 2 It is a structural sectional view of the cleaning station for the reaction cup of the present utility model;
[0023] Figure 3 It is an exploded view of the cleaning station for the reaction cup of the present utility model;
[0024] Figure 4 It is a three-dimensional structural diagram of the megasonic cleaning unit of the present utility model;
[0025] Figure 5 It is a structural sectional view of the megasonic cleaning unit of the present utility model;
[0026] Figure 6 It is a three-dimensional structural diagram of the flushing unit of the present utility model;
[0027] Figure 7 It is a structural sectional view of the flushing unit of the present utility model;
[0028] Figure 8 It is a schematic structural diagram of the lifting unit of the present utility model. DETAILED DESCRIPTION OF THE EMBODIMENTS
[0029] In order to make the objectives, technical solutions and advantages of the present utility model clearer, the technical solutions of the present utility model will be clearly and completely described below in conjunction with the specific embodiments of the present utility model and the corresponding accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all of the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts fall within the scope of protection of the present utility model.
[0030] In this embodiment, it is aimed at the technical problem that in the reagent for the immunoturbidimetry project, there are latex particles (the diameter of the latex particles is generally between 80 nm and 300 nm, and the latex particles are easily adsorbed on the inner wall surface of the reaction cup during the test); the traditional cleaning method of the analyzer uses cleaning liquid and water to dilute, rinse, and surface rinse the reaction cup; and with the cooperation of conventional ultrasonic cleaning, it is difficult to clean it thoroughly, and a detailed description is given.
[0031] A cleaning station for a reaction cup according to an embodiment of the present application, as Figures 1-7 shown, which includes: a megasonic cleaning unit 1 for stripping latex particles with a diameter of 80 nm - 300 nm attached to the reaction cup wall;
[0032] a rinsing unit 2 for rinsing the stripped latex particles;
[0033] The megasonic cleaning unit 1 includes more than one ultrasonic generator 11, a transducer 12, and a reflection baffle 13. In order to strip the latex particles cleanly, there are four groups of ultrasonic generators 11, and the four groups of ultrasonic generators 11 are the front-segment ultrasonic generator 111, the middle-segment ultrasonic generator 112, the rear-segment ultrasonic generator 113, and the end-segment ultrasonic generator 114 arranged at intervals from top to bottom in sequence; the ultrasonic generator 11 is electrically connected to the transducer 12, and the ultrasonic generator 11 provides electrical energy and generates a high-frequency sine current signal; the transducer 12 converts the electrical energy into mechanical vibration energy and generates ultrasonic waves. It should be noted that the structures and working processes of the ultrasonic generator 11 and the transducer 12 are both prior arts and will not be elaborated here; the reflection baffle 13 is arranged on the side of the transducer 12, and a reaction cup channel 14 is formed between the reflection baffle 13 and the transducer 12. The reaction cup channel 14 is used for placing the reaction cup 4 during cleaning. During cleaning, both the transducer 12 and the reflection baffle 13 are located on the water bath tank 3, and the transducer 12 and the reflection baffle 13 are respectively located on both sides of the reaction cup channel 14; the reaction cup 4 is connected to the reaction cup holder 5; a limiting groove 51 is provided on the reaction cup holder 5, and the elastic piece of the reaction cup 4 is matched with the limiting groove 51 so that the reaction cup 4 is not easily moved after installation; a reaction cup support 52 is provided on the reaction cup holder 5 for supporting the reaction cup 4.
[0034] Furthermore, the vibration frequency of the transducer 12 is 0.8 MHz to 1.65 MHz. High-energy ultrasonic waves with a wavelength not greater than 1 μm and a frequency above 0.8 MHz are emitted by the transducer 12. The liquid molecules on the wall of the reaction cup 4 move in an accelerated manner under the push of this high-energy ultrasonic wave, continuously impacting the surface of the wall of the reaction cup 4 with a high-speed fluid wave, so that the latex particles attached to the surface of the wall of the reaction cup 4 are forcibly removed and enter the cleaning liquid, thereby stripping the latex particles with a diameter of 80 nm - 300 nm attached to the wall of the reaction cup 4 from the wall of the reaction cup 4.
[0035] Among them, the reflection baffle 13 is made of stainless steel, and its functions are as follows: reflecting ultrasonic waves to the cup wall of the reaction cup 4 opposite to the transducer 12, reducing the problem of inconsistent stripping effects of latex particles on both sides of the cup wall of the reaction cup 4 caused by power loss; the reflection baffle is set according to the structure of the reaction cup 4 and can be in various forms such as a straight plate or a bent plate; the reflection baffle 13 is used to enhance the reflection effect of ultrasonic waves and optimize the accuracy of measurement or detection.
[0036] As a further explanation, as Figures 4-5 shown, the megasonic cleaning unit 1 further includes a base 15, and the ultrasonic generator 11 is connected to the base 15; a reaction cup channel 14 is formed on the base 15, the transducer 12 and the reflection baffle 13 are respectively connected to the base 15, and the transducer 12 and the reflection baffle 13 are respectively located on both sides of the reaction cup channel 14; the base 15 is connected to the water bath 3 through a connector 16, so that the transducer 12 and the reflection baffle 13 are located in the water bath 3, facilitating the installation of the megasonic cleaning unit 1.
[0037] Specifically, as Figures 6-7 shown, the flushing unit 2 includes a liquid suction needle 21. There is one liquid suction needle 21, and liquid injection needles 22 are respectively arranged on both sides of the liquid suction needle 21. The two liquid injection needles 22 are symmetrically arranged with respect to the center line of the liquid suction needle 21; the liquid suction needle 21 is used to suck the cleaned liquid in the reaction cup 4, and the liquid injection needles 22 are used to inject cleaning liquid into the reaction cup 4; the liquid outlet of the liquid injection needle 22 is higher than the liquid outlet of the liquid suction needle 21; the liquid outlet of the liquid injection needle 22 forms a 45-degree angle with the center line of the liquid suction needle 21; the liquid injection needle 22 flushes the cup wall of the reaction cup 4 during the liquid injection process, making the latex particles peeled off from the cup wall of the reaction cup 4 by the megasonic cleaning unit 1 away from the cup wall of the reaction cup 4, avoiding the secondary attachment of latex particles to the cup wall of the reaction cup 4; the suction working principles of the liquid injection needle 22 and the liquid suction needle 21 are prior arts and will not be elaborated here;
[0038] It should be noted that in order to achieve better cleaning effects, multiple groups of flushing units 2 are configured. In this example, there are seven groups of flushing units 2. Each reaction cup 4 rotates the reaction cup holder 5 through a rotating disk for cleaning in sequence; finally, a cleaning brush is also provided to further clean the reaction cup 4; in each group of flushing units 2, the megasonic cleaning unit 1 keeps working continuously to peel off the latex particles on the cup wall of the reaction cup 4.
[0039] As a further explanation, as Figures 6-7As shown, the liquid suction needle 21 and the liquid injection needle 22 are integrated through the packing 23. The integrated liquid suction needle 21 and liquid injection needle 22 are connected to the outer tube 24, making it more convenient to install the liquid suction needle 21 and the liquid injection needle 22. A fixing plate 25 is connected to the outer tube 24 for convenient fixing. Both ends of the liquid suction needle 21 and the liquid injection needle 22 extend to the outside of the outer tube 24, that is, the outer tube 24 plays a role of relative fixation.
[0040] Furthermore, as Figure 8 shown, it further includes a lifting unit 6. The lifting unit 6 includes a base 61 and a lifting seat 62. The base 61 is connected to the water bath tank 3. The lifting seat 62 is slidably connected to the base 61 through the cooperation of a slider and a slide rail, and the lifting seat 62 can move up and down on the base 61. A lifting motor 63 is connected to the base 61, and the output end of the lifting motor 63 is connected to the lifting seat 62. The lifting motor 63 drives the lifting seat 62 to lift on the base 61. The flushing unit 2 is connected to the lifting seat 62, and the flushing unit 2 moves up and down in the reaction cup channel 14, as Figure 5 shown. The flushing unit 2 is connected to the lifting seat 62 through the fixing plate 25. The operation of the flushing unit 2 is divided into two sections: the downward movement and the upward movement. Among them, during the downward movement, the liquid suction needle 21 sucks dry the liquid in the reaction cup 4, and during the upward movement, liquid is injected into the reaction cup 4 while sucking away the liquid. In this way, the liquid with suspended latex particles can be sucked dry and cleaning liquid and purified water can be injected, thereby realizing the cleaning of the latex particles attached to the inner wall surface of the reaction cup and avoiding the attachment of latex particles on the surface of the reaction cup.
[0041] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.
[0042] Unless otherwise specifically stated, the relative arrangements, numerical expressions, and numerical values of the components and steps set forth in these embodiments do not limit the scope of the present application. At the same time, it should be understood that, for the sake of convenience of description, the dimensions of the various parts shown in the drawings are not drawn in actual proportional relationships. Technologies, methods, and devices known to those of ordinary skill in the relevant art may not be discussed in detail, but where appropriate, the technologies, methods, and devices should be regarded as part of the specification. In all the examples shown and discussed here, any specific values should be construed as merely exemplary and not as a limitation. Therefore, other examples of the exemplary embodiments may have different values. It should be noted that like reference numerals and letters denote like items in the following drawings, and thus, once an item is defined in one drawing, it does not need to be further discussed in subsequent drawings.
[0043] In the description of the present application, it should be understood that the orientation or positional relationships indicated by orientation terms such as "front, rear, upper, lower, left, right", "lateral, vertical, perpendicular, horizontal", and "top, bottom" are generally based on the orientation or positional relationships shown in the drawings, and are only for the convenience of describing the present application and simplifying the description. Without contrary description, these orientation terms do not indicate and imply that the device or element referred to must have a specific orientation or be constructed and operated in a specific orientation, and thus should not be construed as limiting the protection scope of the present application; the orientation terms "inside, outside" refer to the inside and outside relative to the contour of each component itself.
[0044] For the convenience of description, spatial relative terms such as "above", "over", "on the upper surface", "above" can be used here to describe the spatial positional relationships of a device or feature shown in the drawings with other devices or features. It should be understood that the spatial relative terms are intended to include different orientations in use or operation in addition to the orientation described in the drawings for the device. For example, if the device in the drawing is inverted, the device described as "above" or "over" other devices or structures will then be positioned "below" or "under" other devices or structures. Thus, the exemplary term "above" can include both the orientations of "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and corresponding interpretations should be made for the spatial relative descriptions used here.
[0045] In addition, it should be noted that the use of terms such as "first", "second" to limit components is only for the convenience of differentiating the corresponding components. Without otherwise stating, the above terms have no special meanings, and thus should not be construed as limiting the protection scope of the present application.
[0046] In the description of the present utility model, it should be noted that unless otherwise clearly specified and defined, terms such as "installation", "provided with", "connection", etc. should be understood in a broad sense. For example, "connection" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.
[0047] The above are only the preferred embodiments of the present utility model, and all equivalent changes and modifications made according to the scope of the patent application of the present utility model shall fall within the scope covered by the present utility model.
Claims
1. A cleaning station for a reaction cup, characterized in that: It comprises: a megasonic cleaning unit and a flushing unit, wherein the megasonic cleaning unit is used to peel off the latex particles attached to the wall of the reaction cup; and the flushing unit flushes the peeled latex particles; The megasonic cleaning unit comprises one or more ultrasonic generators, transducers and reflective baffles, wherein the ultrasonic generator is electrically connected to the transducer, the reflective baffle is arranged on the side of the transducer, a reaction cup channel is formed between the reflective baffle and the transducer, the transducer and the reflective baffle are both located on the water bath, and the transducer and the reflective baffle are respectively located on both sides of the reaction cup channel; the reaction cup is connected to the reaction cup rack; The flushing unit comprises a liquid aspiration needle, and liquid injection needles are respectively arranged on both sides of the liquid aspiration needle.
2. The cleaning station for reaction cups according to claim 1, characterized in that: The ultrasonic generators are a front section ultrasonic generator, a middle section ultrasonic generator, a rear section ultrasonic generator and a terminal section ultrasonic generator which are sequentially arranged at intervals from top to bottom.
3. The cleaning station for reaction cups according to claim 1, characterized in that: The reaction cup rack is provided with a limiting groove, and the spring piece of the reaction cup matches with the limiting groove.
4. The cleaning station for reaction cups as claimed in claim 3, characterized in that: The reaction cup rack is provided with a reaction cup support.
5. The cleaning station for reaction cups according to claim 1, characterized in that: The vibration frequency of the transducer is 0.8 MHz to 1.65 MHz.
6. The cleaning station for reaction cups according to claim 1, characterized in that: The reflective baffle is made of stainless steel.
7. The cleaning station for a reaction cup as claimed in claim 1, characterized in that: The megasonic cleaning unit also includes a base, the ultrasonic generator is connected to the base; a reaction cup channel is formed on the base, the transducer and the reflective baffle are respectively connected to the base; the base is connected to a water bath through a connector, and the transducer and the reflective baffle are located in the water bath.
8. The cleaning station for reaction cups as claimed in claim 1, characterized in that: The liquid outlet of the injection needle is higher than the liquid outlet of the aspiration needle; the liquid outlet of the injection needle is 45 degrees to the center line of the aspiration needle; and the two injection needles are symmetrically arranged with respect to the center line of the aspiration needle.
9. The cleaning station for reaction cups according to claim 1, characterized in that: The aspiration needle and the injection needle are integrated by a filler, and the integrated aspiration needle and injection needle are connected to an outer tube, and a fixing plate is connected to the outer tube.
10. The cleaning station for reaction cups according to claim 9, characterized in that: It also includes a lifting unit, which includes a base and a lifting seat, the base is connected to the water bath; the lifting seat is slidably connected to the base, and the lifting seat can move up and down on the base; the base is connected to a lifting motor, the output end of the lifting motor is connected to the lifting seat, the flushing unit is connected to the lifting seat, and the flushing unit is connected to the lifting seat through a fixed plate.