Reagent pipetting device

Abstract

The utility model provides a reagent pipetting device and belongs to the technical field of reagent pipetting. The reagent pipetting device comprises a workbench, a translation mechanism, a translation table, a lifting frame, a first lead screw, a lifting plate, an electric push rod, a hanging bracket, a pipettor, a base, a slewing bearing assembly, a rotating table and a reagent bottle; the rotary supporting assembly is installed on the base, the rotary table is installed on the rotary supporting assembly, and the reagent bottle is embedded into the containing groove of the rotary table, so that the rotary table can drive the reagent bottle to rotate so as to adjust the position of the reagent bottle, and therefore when the pipettor injects a reagent liquid into the reagent bottle, the reagent liquid can be conveniently poured into the reagent bottle. According to the technical scheme, a worker can replace the reagent bottle without stopping the product, so that the condition that the time for replacing the reagent bottle occupies the time for transferring the reagent is avoided, and the working efficiency of the product is further improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of reagent pipetting, and particularly relates to a reagent pipetting device. Background Art

[0002] In the related art, during a biological experiment, a reagent stock solution needs to be pipetted into a reagent tank through a pipetting device to facilitate the biological experiment on the reagent.

[0003] The prior art (publication number: CN211784544U) discloses a biological reagent pipetting device for tumor research. The liquid supply mechanism works by driving a lead screw to rotate through a lead screw motor. Through the cooperation and transmission of the lead screw and the lead screw nut, the sliding seat is driven to slide left and right on two guide rails, thereby driving the liquid storage tank and the liquid outlet head to move horizontally left and right, and releasing reagents into different liquid storage holes on the upper liquid loading plate and the lower liquid loading plate. The reagent released by the liquid outlet head can directly drop into the liquid storage hole at the upper end of the upper liquid loading plate, or can drop into the liquid storage hole at the upper end of the lower liquid loading plate through the liquid outlet head after the vertical pipetting mechanism works to drive the lower liquid loading plate to move upward, thereby improving the test efficiency.

[0004] In this prior art, when the reagent storage hole is full, it is necessary to stop the machine to replace the liquid storage hole, which occupies the reagent pipetting time and thus reduces the working efficiency of the product. Summary of the Utility Model

[0005] In order to solve the problem existing in the above prior art that when the reagent storage hole is full, it is necessary to stop the machine to replace the liquid storage hole, which occupies the reagent pipetting time and thus reduces the working efficiency of the product, the utility model provides a reagent pipetting device. The rotary table can drive the reagent bottle to rotate to adjust the position of the reagent bottle, so that when the pipettor injects the reagent liquid into the reagent bottle, the staff can replace the reagent bottle without stopping the product, so as to avoid occupying the reagent pipetting time due to replacing the reagent bottle, and further improve the working efficiency of the product. The specific technical solution is as follows:

[0006] A reagent pipetting device, the reagent pipetting device comprising: a workbench, a translation mechanism, a translation stage, a lifting frame, a first lead screw, a lifting plate, an electric push rod, a hanging frame, a pipette, a base, a slewing bearing assembly, a rotating stage and a reagent bottle; the translation mechanism is installed on the workbench; the translation stage is connected to the translation mechanism; the lifting frame is fixed on the translation stage; a first external thread is provided on the outer wall of the first lead screw, one end of the first lead screw is rotatably connected to the lifting frame, and the other end of the first lead screw is rotatably connected to the translation stage; a first threaded hole is provided in the lifting plate, a first internal thread is provided in the first threaded hole, at least part of the lifting plate is embedded in the lifting frame, and the first lead screw passes through the first threaded hole of the lifting plate; the electric push rod is fixed on the lifting plate; the hanging frame is connected to the bottom of the lifting plate; the pipette is installed in the hanging frame, and the button of the pipette is connected to the electric push rod. The base is installed on the workbench, and the base is located on one side of the translation mechanism; the slewing bearing assembly is installed on the base; a plurality of receiving grooves are provided on the rotating stage, and the rotating stage is installed on the slewing bearing assembly; the reagent bottle is a hollow cavity with an opening at the top, and a plurality of reagent bottles are respectively embedded in the plurality of receiving grooves; wherein, the first external thread is adapted to the first internal thread.

[0007] In addition, the reagent pipetting device in the above technical solution provided by the present utility model may further have the following additional technical features:

[0008] In the above technical solution, the reagent pipetting device further comprises: a first optical bar; one end of two first optical bars is connected to the lifting frame, the other end of the two first optical bars is connected to the translation stage, and the two first optical bars pass through the lifting plate; wherein, the two first optical bars are located on both sides of the first lead screw.

[0009] In the above technical solution, the reagent pipetting device further comprises: a first motor; the first motor is provided with a first output shaft, the first motor is fixed on the lifting frame, and the first output shaft of the first motor is connected to the first lead screw.

[0010] In the above technical solution, the translation mechanism comprises: a support plate, a second threaded hole and a second lead screw; two support plates are fixed on the workbench, and there is a distance between the two support plates; a second internal thread is provided in the second threaded hole, and the second threaded hole runs through the translation stage; a second external thread is provided on the outer wall of the second lead screw, both ends of the second lead screw are rotatably connected to the two support plates respectively, and the second lead screw passes through the second threaded hole; wherein, the second internal thread is adapted to the second external thread.

[0011] In the above technical solution, the translation mechanism further comprises: a second optical bar; both ends of the second optical bar are respectively connected to the two support plates, and the second optical bar passes through the translation stage.

[0012] In the above technical solution, the translation mechanism further includes: a second motor; the second motor is provided with a second output shaft, the second motor is fixed on the workbench, and the second output shaft of the second motor is connected to the second lead screw.

[0013] A reagent pipetting device of the present utility model has the following beneficial effects compared with the prior art:

[0014] 1. By installing the slewing bearing assembly on the base, installing the rotating table on the slewing bearing assembly, and embedding the reagent bottle into the receiving groove of the rotating table, the rotating table can drive the reagent bottle to rotate to adjust the position of the reagent bottle, so that when the pipette injects the reagent liquid into the reagent bottle, the staff can replace the reagent bottle without stopping the product, avoiding occupying the time of reagent pipetting due to replacing the reagent bottle, and thus improving the working efficiency of the product.

[0015] 2. By passing two first optical bars through the lifting plate and making the two first optical bars located on both sides of the first lead screw, the lifting plate can move along the first optical bars, avoiding the lifting plate from shifting during movement and improving the stability of the up and down movement of the lifting plate.

[0016] 3. By fixing the first motor on the lifting frame and connecting the first output shaft of the first motor to the first lead screw, the first motor can drive the first lead screw to rotate, providing power for rotating the first lead screw.

[0017] 4. By passing the second threaded hole through the translation table and making the second lead screw pass through the second threaded hole, the second lead screw is threadedly connected to the translation table, so that rotating the second lead screw can drive the translation table to move and adjust the position of the translation table.

[0018] 5. By connecting the two ends of the second optical bar to the two support plates respectively and making the second optical bar pass through the translation table, the two support plates can support the second optical bar, so that the translation table can move along the second optical bar, avoiding the translation table from shifting during movement and improving the stability of the movement of the translation table.

[0019] 6. By fixing the second motor on the workbench and connecting the second output shaft of the second motor to the second lead screw, the second motor can drive the second lead screw to rotate, providing power for rotating the second lead screw. Description of the Drawings

[0020] Figure 1 is a cross-sectional view of the reagent pipetting device of the present utility model;

[0021] Figure 2 is Figure 1 a partial enlarged view of part A of

[0022] Figure 3 Top view of the reagent pipetting device of the present utility model;

[0023] Among them, Figures 1 to 3 The corresponding relationship between the reference numerals and the component names in the figure is as follows:

[0024] 10 Workbench, 11 Translation mechanism, 111 Support plate, 112 Second lead screw, 113 Second optical bar, 114 Second motor, 12 Translation stage, 13 Lifting frame, 14 First lead screw, 15 Lifting plate, 16 Electric push rod, 17 Hanging bracket, 18 Pipettor, 19 Base, 20 Slewing bearing assembly, 21 Rotating table, 22 Reagent bottle, 23 First optical bar, 24 First motor. Specific embodiments

[0025] The following combines specific implementation cases and attached drawings Figures 1 to 3 To further illustrate the present utility model, but the present utility model is not limited to these embodiments.

[0026] A reagent pipetting device, as Figures 1 to 3 shown, the reagent pipetting device includes: a workbench 10, a translation mechanism 11, a translation stage 12, a lifting frame 13, a first lead screw 14, a lifting plate 15, an electric push rod 16, a hanging bracket 17, a pipettor 18, a base 19, a slewing bearing assembly 20, a rotating table 21 and a reagent bottle 22; the translation mechanism 11 is installed on the workbench 10; the translation stage 12 is connected to the translation mechanism 11; the lifting frame 13 is fixed on the translation stage 12; a first external thread is provided on the outer wall of the first lead screw 14, one end of the first lead screw 14 is rotatably connected to the lifting frame 13, and the other end of the first lead screw 14 is rotatably connected to the translation stage 12; a first threaded hole is provided in the lifting plate 15, a first internal thread is provided in the first threaded hole, at least part of the lifting plate 15 is embedded in the lifting frame 13, and the first lead screw 14 passes through the first threaded hole of the lifting plate 15; the electric push rod 16 is fixed on the lifting plate 15; the hanging bracket 17 is connected to the bottom of the lifting plate 15; the pipettor 18 is installed in the hanging bracket 17, and the button of the pipettor 18 is connected to the electric push rod 16. The base 19 is installed on the workbench 10, and the base 19 is located on one side of the translation mechanism 11; the slewing bearing assembly 20 is installed on the base 19; a plurality of receiving grooves are provided on the rotating table 21, and the rotating table 21 is installed on the slewing bearing assembly 20; the reagent bottle 22 is a hollow cavity with an opening at the top, and a plurality of reagent bottles 22 are respectively embedded in a plurality of receiving grooves; among them, the first external thread is adapted to the first internal thread.

[0027] By installing the translation mechanism 11 on the workbench 10 and connecting the translation table 12 to the translation mechanism 11, the translation mechanism 11 can drive the translation table 12 to move, thereby adjusting the position of the translation table 12; by fixing the lifting frame 13 on the translation table 12, rotatably connecting one end of the first lead screw 14 to the lifting frame 13, and rotatably connecting the other end of the first lead screw 14 to the translation table 12, the lifting frame 13 and the translation table 12 cooperate to support the first lead screw 14, so that the first lead screw 14 can rotate within the lifting frame 13. By embedding at least part of the lifting plate 15 into the lifting frame 13 and passing the first lead screw 14 through the first threaded hole of the lifting plate 15, the first lead screw 14 is threadedly connected to the lifting plate 15, so that rotating the first lead screw 14 can drive the lifting plate 15 to move up and down; by fixing the electric push rod 16 on the lifting plate 15, connecting the hanging frame 17 to the bottom of the lifting plate 15, and installing the pipette 18 in the hanging frame 17, the lifting plate 15 can drive the electric push rod 16 and the hanging frame 17 to move up and down synchronously, so that the pipette 18 and the electric push rod 16 move up and down synchronously; at the same time, by connecting the electric push rod 16 to the button of the pipette 18, the electric push rod 16 can start the pipette 18 to work, so that the pipette 18 can extract and discharge the reagent liquid. By installing the base 19 on the workbench 10, installing the slewing bearing assembly 20 on the base 19, and installing the rotating table 21 on the slewing bearing assembly 20, the rotating table 21 can rotate relative to the workbench 10; by providing a plurality of receiving grooves on the rotating table 21 and respectively embedding a plurality of reagent bottles 22 into the plurality of receiving grooves, the rotating table 21 can accommodate the reagent bottles 22 through the receiving grooves, so that the rotating table 21 can drive the reagent bottles 22 to rotate, and further the reagent bottles 22 can be located below the pipette 18 to ensure that the pipette 18 can inject the reagent liquid into the reagent bottles 22.

[0028] When specifically using the product, first place the reagent stock solution tank on the workbench 10, and make the reagent stock solution tank located below the pipette 18; then, rotate the first lead screw 14 to drive the lifting plate 15 to move downward by the first lead screw 14, so that the pipette 18 is inserted into the reagent stock solution tank; then, start the electric push rod 16 to press the pipette 18 by the electric push rod 16, so that the pipette 18 extracts the reagent liquid in the reagent stock solution tank; then, rotate the first lead screw 14 in the reverse direction to drive the lifting plate 15 to move upward by the first lead screw 14, so that the pipette 18 is removed from the reagent stock solution tank; then, start the translation mechanism 11 to drive the translation table 12 to move by the translation mechanism 11, so that the pipette 18 is located above the reagent bottle 22; then, rotate the first lead screw 14 to drive the lifting plate 15 to move downward by the first lead screw 14, so that the pipette 18 is inserted into the reagent bottle 22; then, start the electric push rod 16 to press the button of the pipette 18 by the electric push rod 16, so that the reagent liquid is injected into the reagent bottle 22; then, rotate the first lead screw 14 in the reverse direction to drive the lifting plate 15 to move upward by the first lead screw 14, so that the pipette 18 is removed from the reagent bottle 22; then, start the translation mechanism 11 to drive the pipette 18 to move above the reagent stock solution tank by the translation mechanism 11; at the same time, rotate the rotating table 21 to rotate the empty reagent bottle 22 to a predetermined position. At this time, the staff can replace the reagent bottle 22 that has been injected with the reagent liquid.

[0029] With the above structure, by installing the slewing bearing assembly 20 on the base 19, installing the rotating table 21 on the slewing bearing assembly 20, and inserting the reagent bottle 22 into the receiving groove of the rotating table 21, it is realized that the rotating table 21 can drive the reagent bottle 22 to rotate to adjust the position of the reagent bottle 22, so that when the pipette 18 injects the reagent liquid into the reagent bottle 22, the staff can replace the reagent bottle 22 without stopping the product, so as to avoid occupying the reagent pipetting time due to replacing the reagent bottle 22, and further improve the working efficiency of the product.

[0030] Specifically, the slewing bearing assembly 20 includes an inner ring, an outer ring, and rolling elements. A plurality of rolling elements are simultaneously inserted into the inner ring and the outer ring so that the inner ring and the outer ring can rotate relative to each other; wherein the inner ring is connected to the rotating table 21, and the outer ring is fixed on the base 19.

[0031] Specifically, the driving device is installed in the base 19; the driving device is connected to the gear, and the gear meshes with the internal teeth of the inner ring, so that the driving device can drive the inner ring to rotate, and further drive the rotating table 21 to rotate.

[0032] In the embodiment of the present invention, as Figure 1 and Figure 2As shown, the reagent pipetting device further includes: a first optical bar 23; one end of two first optical bars 23 is connected to the lifting frame 13, the other end of the two first optical bars 23 is connected to the translation stage 12, and the two first optical bars 23 pass through the lifting plate 15; wherein, the two first optical bars 23 are located on both sides of the first lead screw 14.

[0033] By connecting one end of the two first optical bars to the lifting frame 13 and connecting the other end of the two first optical bars 23 to the translation stage 12, the lifting frame 13 and the translation stage 12 are adapted to support the two first optical bars 23, thereby improving the stability of the first optical bar 23; by passing the two first optical bars 23 through the lifting plate 15 and making the two first optical bars 23 located on both sides of the first lead screw 14, the lifting plate 15 can move along the first optical bar 23, thereby preventing the lifting plate 15 from shifting during movement and improving the stability of the up and down movement of the lifting plate 15.

[0034] In an embodiment of the present invention, as Figure 1 and Figure 2 shown, the reagent pipetting device further includes: a first motor 24; the first motor 24 is provided with a first output shaft, the first motor 24 is fixed on the lifting frame 13, and the first output shaft of the first motor 24 is connected to the first lead screw 14.

[0035] By fixing the first motor 24 on the lifting frame 13 and connecting the first output shaft of the first motor 24 to the first lead screw 14, the first motor 24 can drive the first lead screw 14 to rotate, thereby providing power for rotating the first lead screw 14.

[0036] In an embodiment of the present invention, as Figure 3 shown, the translation mechanism 11 includes: a support plate 111, a second threaded hole and a second lead screw 112; two support plates 111 are fixed on the workbench 10, and there is a distance between the two support plates 111; the second threaded hole is provided with a second internal thread, and the second threaded hole runs through the translation stage 12; the outer wall of the second lead screw 112 is provided with a second external thread, the two ends of the second lead screw 112 are respectively rotatably connected to the two support plates 111, and the second lead screw 112 passes through the second threaded hole; wherein, the second internal thread is adapted to the second external thread.

[0037] By fixing two support plates 111 on the workbench 10 and rotatably connecting both ends of the second lead screw 112 to the two support plates 111 respectively, the two support plates 111 support the second lead screw 112, so that the second lead screw 112 can rotate between the two support plates 111; by passing the second threaded hole through the translation stage 12 and making the second lead screw 112 pass through the second threaded hole, the second lead screw 112 is threadedly connected to the translation stage 12, so that rotating the second lead screw 112 drives the translation stage 12 to move, thereby adjusting the position of the translation stage 12.

[0038] In an embodiment of the present invention, as Figure 3 shown, the translation mechanism 11 further includes: a second optical bar 113; both ends of the second optical bar 113 are connected to the two support plates 111 respectively, and the second optical bar 113 passes through the translation stage 12.

[0039] By connecting both ends of the second optical bar 113 to the two support plates 111 respectively and making the second optical bar 113 pass through the translation stage 12, the two support plates 111 support the second optical bar 113, so that the translation stage 12 can move along the second optical bar 113, avoiding the translation stage 12 from shifting during movement, and thus improving the stability of the movement of the translation stage 12.

[0040] In an embodiment of the present invention, as Figure 3 shown, the translation mechanism 11 further includes: a second motor 114; the second motor 114 is provided with a second output shaft, the second motor 114 is fixed on the workbench 10, and the second output shaft of the second motor 114 is connected to the second lead screw 112.

[0041] By fixing the second motor 114 on the workbench 10 and connecting the second output shaft of the second motor 114 to the second lead screw 112, the second motor 114 can drive the second lead screw 112 to rotate, thereby providing power for rotating the second lead screw 112.

[0042] In the description of the present utility model, the term "a plurality of" means two or more, unless otherwise clearly defined. The orientation or positional relationship indicated by terms such as "upper", "lower", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the present utility model; terms such as "connection", "installation", "fixation", etc. should all be understood in a broad sense. For example, "connection" can be a fixed connection, a detachable connection, or an integral connection; it can be directly connected or indirectly connected through an intermediate medium. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0043] In the description of the present utility model, the description of terms such as "one embodiment", "some embodiments", "specific embodiments", etc. means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present utility model. In the present utility model, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in a suitable manner in any one or more embodiments or examples.

[0044] The above is only the preferred embodiment of the present utility model and is not used to limit the present utility model. For those skilled in the art, the present utility model can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. A reagent pipetting device, characterized in that, The reagent pipetting device includes: A workbench; A translation mechanism, which is installed on the workbench; A translation table, which is connected to the translation mechanism; A lifting frame, which is fixed on the translation table; A first lead screw, on the outer wall of which there is a first external thread. One end of the first lead screw is rotatably connected to the lifting frame, and the other end of the first lead screw is rotatably connected to the translation table; A lifting plate, in which there is a first threaded hole provided with a first internal thread. At least part of the lifting plate is embedded in the lifting frame, and the first lead screw passes through the first threaded hole of the lifting plate; An electric push rod, which is fixed on the lifting plate; A hanging frame, which is connected to the bottom of the lifting plate; A pipette, which is installed in the hanging frame, and the button of the pipette is connected to the electric push rod; A base, which is installed on the workbench and is located on one side of the translation mechanism; A slewing bearing assembly, which is installed on the base; A rotating table, on which there are a plurality of receiving grooves, and the rotating table is installed on the slewing bearing assembly; Reagent bottles, each of which is a hollow cavity with an opening at the top, and a plurality of the reagent bottles are respectively embedded in a plurality of the receiving grooves; Wherein, the first external thread is adapted to the first internal thread.

2. The reagent pipetting device according to claim 1, wherein The reagent pipetting device further includes: A first optical bar, one end of each of the two first optical bars is connected to the lifting frame, the other end of each of the two first optical bars is connected to the translation table, and the two first optical bars pass through the lifting plate; Wherein, the two first optical bars are located on both sides of the first lead screw.

3. The reagent pipetting device according to claim 2, wherein, The reagent pipetting device further includes: A first motor, which is provided with a first output shaft, is fixed on the lifting frame, and the first output shaft of the first motor is connected to the first lead screw.

4. The reagent pipetting device according to claim 1, characterized in that, The translation mechanism includes: Support plates, two of which are fixed on the workbench and there is a spacing between the two support plates; A second threaded hole, in which there is a second internal thread, and the second threaded hole runs through the translation table; A second lead screw, on the outer wall of which there is a second external thread. The two ends of the second lead screw are respectively rotatably connected to the two support plates, and the second lead screw passes through the second threaded hole; Wherein, the second internal thread is adapted to the second external thread.

5. A reagent pipetting device according to claim 4, characterized in that, The translation mechanism further includes: A second optical bar, the two ends of which are respectively connected to the two support plates, and the second optical bar passes through the translation table.

6. The reagent pipetting device according to claim 5, characterized in that, The translation mechanism further includes: A second motor, which is provided with a second output shaft, is fixed on the workbench, and the second output shaft of the second motor is connected to the second lead screw.

Images