Intelligent separation device for recombinant III-type humanized collagen

Abstract

The utility model discloses an intelligent separating device for recombinant III type humanized collagen, which belongs to the technical field of bioengineering and comprises a separating shell, a cleaning component, a filtering component, a connecting component and a feeding component, the cleaning component comprises a rotating frame, the lower surface of the rotating frame is connected with a scraping plate, a cavity is arranged in the rotating frame, and the filtering component is arranged in the cavity. A plurality of water spraying holes are formed in the lower surface of the rotating frame, and a motor is connected to the lower surface of the rotating frame; according to the utility model, fermentation liquor flowing out of the rotating bent pipe can uniformly move to the filter screen, and the fermentation liquor can be filtered in the process of flowing along the filter screen, so that each part of the filter screen can be fully utilized, and meanwhile, the rotating frame drives the scraping plate to scrape impurities filtered on the filter screen; and the scraped impurities are pushed into the groove under the action of the rotary scraping plate, so that the cleaned filter screen can efficiently filter the fermentation liquor.

Description

Technical Field

[0001] The utility model belongs to the technical field of bioengineering, and particularly relates to an intelligent separation device for recombinant type III humanized collagen. Background Technique

[0002] Recombinant type III humanized collagen is a protein that is prepared based on the original gene sequence of human type III collagen and is the same as the corresponding part of the amino acid sequence of human type III collagen by using genetic engineering and engineering bacteria fermentation expression technology. The preparation process of recombinant type III humanized collagen is the acquisition of the target gene, gene recombination and vector construction, host cell transformation, cell culture and expression, and host cell fermentation. After fermentation, a series of separation and purification techniques are used to extract recombinant type III humanized collagen from the fermentation broth.

[0003] However, during the filtration process of the existing recombinant type III humanized collagen fermentation broth, the fermentation broth passing through the feed pipe moves to a certain part of the filter screen, making the rest of the filter screen not fully utilized. Moreover, the impurities in the fermentation broth moving to a certain part of the filter screen may block the filter screen, reducing the normal filtration effect of the filter screen. Therefore, an intelligent separation device for recombinant type III humanized collagen is needed to solve the above problems. Content of the Utility Model

[0004] The purpose of the utility model is to provide an intelligent separation device for recombinant type III humanized collagen to solve the problems put forward in the above background technique.

[0005] To achieve the above purpose, the utility model provides the following technical solution: An intelligent separation device for recombinant type III humanized collagen, including a separation shell, a cleaning component, a filtering component, a connecting component, and a feeding component. The cleaning component includes a rotating frame, a scraping plate is connected to the lower surface of the rotating frame, a cavity is opened in the rotating frame, a plurality of water spraying holes are opened on the lower surface of the rotating frame, and a motor is connected to the lower surface of the rotating frame;

[0006] The connecting component includes a connecting pipe, a bent pipe is connected to one side of the connecting pipe, a solenoid valve is clamped in the connecting pipe, and the bottom end of the connecting pipe is connected to the rotating frame;

[0007] The feeding component includes a bearing, the bearing is clamped in the connecting pipe, a feeding hopper is clamped in the bearing, and a water inlet pipe and a liquid inlet pipe are connected to the top of the feeding hopper;

[0008] The filtering component includes a filter screen, and a plurality of grooves are opened on the upper surface of the filter screen.

[0009] As a preferred solution, the cavity is communicated with a plurality of water spraying holes, and the plurality of water spraying holes are respectively arranged on both sides of the scraping plate.

[0010] As a preferred solution, the width of the scraping plate is slightly smaller than the width of the groove.

[0011] As a preferred solution, the separation shell includes an outer shell. A discharge pipe is provided at the bottom of the outer shell. The feed hopper is snap-fitted on the top of the outer shell, and the filter screen is connected inside the outer shell.

[0012] As a preferred solution, a plurality of discharge valves are snap-fitted on the outside of the outer shell, and the positions of the plurality of discharge valves correspond to the positions of the grooves.

[0013] As a preferred solution, the feed hopper is communicated with the water inlet pipe and the liquid inlet pipe. The feed hopper is communicated with the connecting pipe, and the connecting pipe is communicated with the elbow pipe and the cavity.

[0014] Compared with the prior art, the beneficial effects of the present utility model are:

[0015] In the present utility model, the fermented liquid flowing out of the rotating elbow pipe can uniformly move onto the filter screen, and the fermented liquid can complete filtration during the process of flowing along the filter screen, so that all parts of the filter screen can be fully utilized. At the same time, the rotating frame drives the scraping plate to scrape off the impurities filtered on the filter screen, and the scraped impurities are pushed into the groove under the action of the rotating scraping plate, so that the cleaned filter screen can efficiently filter the fermented liquid;

[0016] In the present utility model, by providing a groove, a water spraying hole and a discharge valve, the solenoid valve and a plurality of discharge valves are controlled to be opened, and the cleaning liquid is introduced into the feed hopper through the water inlet pipe. The impurities collected in the groove can flow downward along the inclined groove under the flushing of the cleaning liquid sprayed out of the water spraying hole and then discharged through the opened discharge valve, so that the cleaned impurities can be conveniently cleaned. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 is a front three-dimensional structural schematic diagram of the present utility model;

[0018] Figure 2 is a front three-dimensional sectional structural schematic diagram of the present utility model;

[0019] Figure 3 is a top three-dimensional sectional structural schematic diagram of the present utility model;

[0020] Figure 4 is a three-dimensional structural schematic diagram of the rotating frame of the present utility model.

[0021] In the figure: 1. Separation shell; 11. Outer shell; 12. Discharge pipe; 2. Motor; 3. Cleaning component; 31. Rotating frame; 32. Scraper; 33. Cavity; 34. Water spraying holes; 4. Connecting component; 41. Connecting pipe; 42. Elbow pipe; 43. Solenoid valve; 5. Feeding component; 51. Bearing; 52. Feeding hopper; 53. Water inlet pipe; 54. Liquid inlet pipe; 6. Filtering component; 61. Filter screen; 62. Groove; 7. Drain valve. Detailed implementation mode

[0022] The following further describes the present utility model in conjunction with embodiments.

[0023] The following embodiments are used to illustrate the present utility model, but cannot be used to limit the protection scope of the present utility model. The conditions in the embodiments can be further adjusted according to specific conditions. Any simple improvement of the method of the present utility model under the premise of the concept of the present utility model belongs to the scope required to be protected by the present utility model.

[0024] Please refer to Figures 1-4 , the present utility model provides a recombinant type III humanized collagen intelligent separation device, including a separation shell 1, a cleaning component 3, a filtering component 6, a connecting component 4 and a feeding component 5. The cleaning component 3 includes a rotating frame 31. A scraper 32 is connected to the lower surface of the rotating frame 31. A cavity 33 is opened in the rotating frame 31. A plurality of water spraying holes 34 are opened on the lower surface of the rotating frame 31. The cavity 33 is communicated with the plurality of water spraying holes 34. The plurality of water spraying holes 34 are respectively arranged on both sides of the scraper 32. A motor 2 is connected to the lower surface of the rotating frame 31. By setting the motor 2, the working motor 2 can drive the scraper 32 to rotate through the rotating frame 31;

[0025] The connecting component 4 includes a connecting pipe 41. An elbow pipe 42 is connected to one side of the connecting pipe 41. A solenoid valve 43 is clamped in the connecting pipe 41. The bottom end of the connecting pipe 41 is connected to the rotating frame 31. By setting the solenoid valve 43, the solenoid valve 43 can control the flow direction of the liquid in the connecting pipe 41. When the solenoid valve 43 is closed, the liquid flowing into the top of the connecting pipe 41 can flow out through the elbow pipe 42. When the solenoid valve 43 is opened, the liquid flowing into the top of the connecting pipe 41 can flow into the cavity 33 from its bottom;

[0026] The feeding component 5 includes a bearing 51. The bearing 51 is clamped in the connecting pipe 41. A feeding hopper 52 is clamped in the bearing 51. By setting the bearing 51, the bearing 51 can limit and fix the connecting pipe 41 in the feeding hopper 52;

[0027] The top of the feeding hopper 52 is connected with a water inlet pipe 53 and a liquid inlet pipe 54;

[0028] The filtering component 6 includes a filter screen 61. A plurality of grooves 62 are formed on the upper surface of the filter screen 61. The width of the scraping plate 32 is slightly smaller than the width of the grooves 62. The separation shell 1 includes an outer shell 11. A discharge pipe 12 is provided at the bottom of the outer shell 11. The feed hopper 52 is snap-fitted on the top of the outer shell 11. The filter screen 61 is connected inside the outer shell 11. A plurality of discharge valves 7 are snap-fitted on the outside of the outer shell 11. The positions of the plurality of discharge valves 7 correspond to the positions of the grooves 62. The feed hopper 52 is communicated with the water inlet pipe 53 and the liquid inlet pipe 54. The feed hopper 52 is communicated with the connecting pipe 41. The connecting pipe 41 is communicated with the elbow pipe 42 and the cavity 33. By providing the grooves 62, the water spray holes 34 and the discharge valves 7, the control solenoid valve 43 and the plurality of discharge valves 7 are opened, and the cleaning liquid is introduced into the feed hopper 52 through the water inlet pipe 53. The impurities collected in the grooves 62 can flow downward along the inclined grooves 62 under the flushing of the cleaning liquid sprayed from the water spray holes 34 and then discharged through the opened discharge valves 7, so that the cleaned impurities can be conveniently cleaned up.

[0029] The working principle and usage process of the present utility model: When the device needs to be used, the control solenoid valve 43 is closed, and the fermentation broth is introduced into the feed head through the liquid inlet pipe 54. The fermentation broth is discharged from the elbow pipe 42 through the feed hopper 52 and the connecting pipe 41, so that the fermentation broth moves onto the filter screen 61. Because the working motor 2 drives the elbow pipe 42 to rotate through the rotating frame 31 and the connecting pipe 41, the fermentation broth flowing out of the elbow pipe 42 can move along the circumference onto the filter screen 61. Then the filter screen 61 can clean the impurities in the fermentation broth. At the same time, the rotating rotating frame 31 drives the scraping plate 32 to scrape off the impurities filtered on the filter screen 61, and the scraped impurities are pushed into the grooves 62 under the action of the rotating scraping plate 32, so that the cleaned filter screen 61 can efficiently filter the fermentation broth. Then the filtered fermentation broth is discharged through the discharge pipe 12;

[0030] When the filter screen 61 needs to be cleaned, the control solenoid valve 43 and the plurality of discharge valves 7 are opened, and at the same time, the motor 2 is controlled to work. The working motor 2 drives the rotating frame 31 to rotate above the filter screen 61. The cleaning liquid is introduced into the feed hopper 52 through the water inlet pipe 53. The cleaning liquid flows into the cavity 33 through the connecting pipe 41 and the solenoid valve 43. The cleaning liquid in the cavity 33 is evenly sprayed on the filter screen 61 through a plurality of water spray holes 34. When the cleaning liquid is sprayed into the grooves 62, the impurities collected in the grooves 62 can flow downward along the inclined grooves 62 under the flushing of the cleaning liquid and then be discharged through the opened discharge valves 7.

[0031] Although the embodiments of the present utility model have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present utility model. The scope of the present utility model is defined by the appended claims and their equivalents.

Claims

1. A recombinant type III humanized collagen intelligent separation device, comprising a separation shell (1), a cleaning component (3), a filtering component (6), a connecting component (4) and a feeding component (5), characterized in that: The cleaning component (3) includes a rotating frame (31). A scraping plate (32) is connected to the lower surface of the rotating frame (31). A cavity (33) is formed in the rotating frame (31). A plurality of water spray holes (34) are formed in the lower surface of the rotating frame (31). A motor (2) is connected to the lower surface of the rotating frame (31). The connecting component (4) includes a connecting pipe (41). A bent pipe (42) is connected to one side of the connecting pipe (41). A solenoid valve (43) is clamped in the connecting pipe (41). The bottom end of the connecting pipe (41) is connected to the rotating frame (31). The feeding component (5) includes a bearing (51). The bearing (51) is clamped in the connecting pipe (41). A feeding hopper (52) is clamped in the bearing (51). A water inlet pipe (53) and a liquid inlet pipe (54) are connected to the top of the feeding hopper (52). The filtering component (6) includes a filter screen (61). A plurality of grooves (62) are formed in the upper surface of the filter screen (61).

2. The intelligent separation device for recombinant type III humanized collagen according to claim 1, wherein: The cavity (33) is communicated with the plurality of water spray holes (34). The plurality of water spray holes (34) are respectively arranged on both sides of the scraping plate (32).

3. The intelligent separation device for recombinant type III humanized collagen according to claim 1, wherein: The width of the scraping plate (32) is slightly smaller than the width of the groove (62).

4. The intelligent separation device for recombinant type III humanized collagen according to claim 1, wherein: The separation shell (1) includes a shell (11). A discharge pipe (12) is arranged at the bottom of the shell (11). The feeding hopper (52) is clamped at the top of the shell (11). The filter screen (61) is connected inside the shell (11).

5. The intelligent separation device for recombinant type III humanized collagen according to claim 4, characterized in that: A plurality of discharge valves (7) are clamped outside the shell (11). The positions of the plurality of discharge valves (7) correspond to the positions of the grooves (62).

6. The intelligent separation device for recombinant type III humanized collagen according to claim 1, wherein: The feeding hopper (52) is communicated with the water inlet pipe (53) and the liquid inlet pipe (54). The feeding hopper (52) is communicated with the connecting pipe (41). The connecting pipe (41) is communicated with the bent pipe (42) and the cavity (33).

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