Grinding device for molecular biology experiment

By using a grinding tooth structure with alternately arranged inner and outer rings in the grinding device for molecular biology experiments, combined with the rotating shaft and the fine grinding drill bit, the continuous crushing and secondary fine grinding of the sample are achieved, solving the problem of sample drop and transfer loss, and improving the grinding degree and detection accuracy of the experiment.

CN223263955UActive Publication Date: 2025-08-26HUNAN AGRI UNIV
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Patent Information

Application Number
CN202422363355.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-27
Publication Date
2025-08-26
Estimated Expiration
2034-09-27

AI Technical Summary

Technical Problem

In existing molecular biology experiments, larger samples are prone to falling from the gap between the grinding teeth, resulting in insufficient grinding, and the secondary grinding operation is complicated and the samples are easily lost during the transfer process, affecting the detection accuracy.

Method used

A grinding device for molecular biology experiments was designed, using a grinding tooth structure with alternately arranged in the inner retaining ring and the outer retaining ring. Combined with the rotating shaft, the grinding wheel and the fine grinding drill bit, the continuous crushing and secondary grinding of the sample are achieved, preventing the sample from falling and reducing transfer losses.

Benefits of technology

Ensure that the sample is fully broken during the grinding process, avoiding the loss and denaturation of the sample during the transfer process, and improving the grinding degree and detection accuracy of the experiment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the field of molecular biology, and discloses a grinding device for molecular biology experiments, which comprises a fixed base, a grinding tank is fixedly connected to the front side of the fixed base, a feeding port is formed in the top end of the grinding tank, a power assembly is arranged at the top end of the grinding tank, and the power assembly is used for providing grinding power. The bottom end of the power assembly is fixedly connected with a rotating shaft, the peripheral face of the rotating shaft is fixedly connected with a grinding wheel, the bottom end of the rotating shaft is fixedly connected with a fine grinding drill bit, the peripheral face of the grinding wheel is fixedly connected with inner grinding teeth, and the interiors of the inner grinding teeth are fixedly connected with inner check rings. According to the utility model, the inner check ring and the outer check ring are arranged, so that an experimental sample can be blocked when falling into a gap between the grinding teeth and can slide down to a gap between the inner grinding teeth and the outer grinding teeth, thereby preventing the sample from falling down along the gap, ensuring that the sample is fully crushed and ground, ensuring the grinding degree of the sample, and directly carrying out secondary accurate grinding.
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Description

Technical Field

[0001] The utility model relates to the field of molecular biology, in particular to a grinding device for molecular biology experiments. Background Art

[0002] Molecular biology is the study of the structure, function, and interactions of biological macromolecules (such as DNA, RNA, and proteins). It explores how these molecules replicate, transcribe, and translate within organisms, regulating the flow of genetic information, thereby revealing the essence of life and the laws of inheritance. Research in this field not only contributes to our understanding of fundamental physiological processes but also significantly advances fields such as medicine, agriculture, and biotechnology.

[0003] Molecular biology experiments often require in-depth study of biological samples. However, these samples are often large or complex in their original state, making them difficult to analyze. Using a grinding device, these samples can be ground into fine particles or powder, increasing the sample's surface area and facilitating subsequent extraction, separation, and purification steps. Therefore, a grinding device for molecular biology experiments is required.

[0004] Currently, molecular biology usually needs to crush and grind larger samples into smaller volumes first, and then place the smaller samples into a fine grinding device for a second fine grinding, so that the samples reach the specified grinding size. In actual use, the first coarse grinding is usually performed using a grinding device with grinding teeth, which is convenient for crushing larger samples. However, in actual use, these larger samples are prone to fall directly from the gaps between the grinding teeth, resulting in some samples failing to reach the grinding degree required for the first grinding in molecular biology. On the other hand, the current equipment needs to take out the sample after coarse grinding and place it into a fine grinding device for a second fine grinding. This setting not only complicates the operation of the equipment, but also causes sample loss during the transfer process, affecting the detection accuracy of the sample. For this reason, a grinding device for molecular biology experiments is proposed to solve the above problems. Utility Model Content

[0005] In order to make up for the above shortcomings, the utility model provides a grinding device for molecular biology experiments, which aims to improve the problems in the existing technology that large samples are prone to falling directly from the gaps between the grinding teeth, and secondary grinding is not only complicated to operate but also easy to cause loss of samples during the transfer process.

[0006] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a grinding device for molecular biology experiments, comprising a fixed base, a grinding jar fixedly connected to the front of the fixed base, a feeding port being provided at the top of the grinding jar, a power assembly being provided at the top of the grinding jar, the power assembly being used to provide grinding power, the bottom end of the power assembly being fixedly connected to a rotating shaft, the outer circumference of the rotating shaft being fixedly connected to a grinding wheel, the bottom end of the rotating shaft being fixedly connected to a fine-grinding drill bit, the outer circumference of the grinding wheel being fixedly connected to inner grinding teeth, the inner part of the inner grinding teeth being fixedly connected to an inner retaining ring, the inner wall of the side of the grinding jar being fixedly connected to outer grinding teeth, the inner part of the outer grinding teeth being fixedly connected to an outer retaining ring, the top of the grinding wheel being fixedly connected to a feeding table, the bottom end of the grinding jar being detachably connected to a fine-grinding assembly, the fine-grinding assembly being used for secondary fine-grinding of the material.

[0007] As a further description of the above technical solution:

[0008] The fine grinding assembly includes a fine grinding seat, the outer peripheral surface of which is detachably connected to the lower inner part of the grinding tank, a grinding cone surface is provided inside the fine grinding seat, a discharge cone surface is provided at the top of the fine grinding seat, and a discharge port is fixedly connected to the bottom of the fine grinding seat.

[0009] As a further description of the above technical solution:

[0010] The power assembly includes a motor bracket, the bottom end of the motor bracket is fixedly connected to the top end of the grinding jar, a rotating motor is fixedly connected inside the motor bracket, and the top end of the rotating shaft is fixedly connected to the output shaft at the bottom end of the rotating motor.

[0011] As a further description of the above technical solution:

[0012] The outer circumference of the rotating shaft is rotatably connected to the interior of the grinding tank, and the interior of the blanking table is fixedly connected to the outer circumference of the rotating shaft.

[0013] As a further description of the above technical solution:

[0014] The inner side of the inner retaining ring is fixedly connected to the outer peripheral surface of the grinding wheel, and the inner and outer sides of the outer retaining ring are fixedly connected to the inner wall of the grinding tank.

[0015] As a further description of the above technical solution:

[0016] The outer side of the inner retaining ring is set as an inclined surface, and the inner side of the outer retaining ring is set as an inclined surface. The inner retaining ring and the outer retaining ring are alternately arranged from top to bottom and are not in the same horizontal plane.

[0017] As a further description of the above technical solution:

[0018] The fine grinding drill bit is arranged inside the grinding cone surface, and the slope of the outer wall inclined surface of the fine grinding drill bit is greater than the slope of the inner wall inclined surface of the grinding cone surface.

[0019] As a further description of the above technical solution:

[0020] The blanking conical surface is configured as a concave surface with a lower inner side and a higher outer side.

[0021] The utility model has the following beneficial effects:

[0022] 1. In the present invention, by providing an inner retaining ring and an outer retaining ring, the experimental sample can be blocked when it falls into the gap between the grinding teeth, and slides into the gap between the inner grinding teeth and the outer grinding teeth, thereby preventing the sample from falling along the gap, ensuring that the sample is fully crushed and ground, ensuring the grinding degree of the sample after rough grinding, and can directly perform secondary fine grinding.

[0023] 2. In the utility model, by setting a rotating shaft, a grinding wheel and a fine grinding drill bit, turning on the rotating motor, the rotating shaft drives the grinding wheel and the fine grinding drill bit to rotate at the same time, so that after the first rough grinding, the sample directly enters the grinding cone surface along the feeding cone surface for the second fine grinding, so that the sample will not be lost or denatured during the transfer process, thereby ensuring the accuracy of the experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a schematic diagram of the overall front view of a grinding device for molecular biology experiments proposed by the present invention;

[0025] Figure 2 This is a schematic cross-sectional view of the top surface of a grinding jar of a grinding device for molecular biology experiments proposed in the present invention;

[0026] Figure 3 This is a front cross-sectional schematic diagram of a grinding jar of a grinding device for molecular biology experiments proposed by the present invention.

[0027] Legend:

[0028] 1. Fixed base; 2. Grinding jar; 3. Feeding port; 4. Motor bracket; 5. Rotating motor; 6. Rotating shaft; 7. Grinding wheel; 8. Inner grinding teeth; 9. Inner retaining ring; 10. Outer grinding teeth; 11. Outer retaining ring; 12. Feeding table; 13. Fine grinding seat; 14. Grinding cone; 15. Feeding cone; 16. Fine grinding drill bit; 17. Feeding port. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0030] Reference Figure 1 - Figure 2 The utility model provides an embodiment of a grinding device for molecular biology experiments, comprising a fixed base 1 that serves as a support and carrying device, a grinding jar 2 being fixedly connected to the front of the fixed base 1, and a feeding port 3 for conveniently putting in samples required for molecular biology experiments being opened on the top of the grinding jar 2, a power assembly being provided on the top of the grinding jar 2, and the power assembly being used to provide grinding power, the power assembly comprising a motor bracket 4 that serves as a fixed support, the bottom end of the motor bracket 4 being fixedly connected to the top of the grinding jar 2, a rotating motor 5 that provides rotational power being fixedly connected to the inside of the motor bracket 4, a rotating shaft 6 being fixedly connected to the bottom end of the power assembly, the top end of the rotating shaft 6 being fixedly connected to the output shaft at the bottom end of the rotating motor 5, and when the rotating motor 5 is turned on, the output shaft at the bottom end of the rotating motor 5 will drive the rotating shaft 6 to rotate, and the outer circumference of the rotating shaft 6 is rotatably connected to the inside of the grinding jar 2, and the outer circumference of the rotating shaft 6 is fixedly connected to a grinding wheel 7.

[0031] Reference Figure 2 - Figure 3The outer circumference of the grinding wheel 7 is fixedly connected with an inner grinding tooth 8, and the inner grinding tooth 8 is provided with multiple groups, which are distributed annularly and equidistantly on the outer circumference of the grinding wheel 7, and an inner retaining ring 9 is fixedly connected to the inner grinding tooth 8. The inner side of the inner retaining ring 9 is fixedly connected to the outer circumference of the grinding wheel 7, and the inner retaining ring 9 is provided with two groups, which are linearly distributed on the outer circumference of the grinding wheel 7 from top to bottom. The inner wall of the side surface of the grinding jar 2 is fixedly connected with an outer grinding tooth 10, and the outer grinding tooth 10 is provided with multiple groups, which are distributed annularly and equidistantly on the inner wall of the side surface of the grinding jar 2, and an outer retaining ring 11 is fixedly connected to the inner grinding tooth 10. The inner and outer sides of the outer retaining ring 11 are fixedly connected to the inner wall of the side surface of the grinding jar 2. The outer retaining ring 11 is provided with three groups, which are linearly distributed on the inner wall of the side surface of the grinding jar 2 from top to bottom. The outer side of the inner retaining ring 9 is set to an inclined surface. When the sample falls onto the inclined surface of the inner retaining ring 9, it will slide to the outside. The inner side of the outer retaining ring 11 is set to The inclined surface, when the sample falls onto the inclined surface of the outer retaining ring 11, it will slide inward. The inner retaining ring 9 and the outer retaining ring 11 are alternately arranged from top to bottom and are not in the same horizontal plane. Therefore, if the sample required for the molecular biology experiment is in the gap of the grinding teeth, it will slide down alternately from the inner retaining ring 9 and the outer retaining ring 11 to ensure that the sample required for the molecular biology experiment is fully crushed. The bottom end of the rotating shaft 6 is fixedly connected to the fine grinding drill bit 16, and the top of the grinding wheel 7 is fixedly connected to the unloading table 12. The side of the unloading table 12 is set as an inclined surface. When the sample required for the molecular biology experiment enters the grinding jar 2 from the feeding port 3, it falls on the unloading table 12 and can fall along the inclined surface between the inner grinding teeth 8 and the outer grinding teeth 10. The inside of the unloading table 12 is fixedly connected to the outer circumferential surface of the rotating shaft 6. The bottom end of the grinding jar 2 is detachably connected to a fine grinding component, which is used for secondary fine grinding of the material.

[0032] Reference Figure 1 and Figure 3 The fine grinding assembly includes a fine grinding seat 13, the outer peripheral surface of the fine grinding seat 13 is detachably connected to the lower inner part of the grinding tank 2, and a grinding cone 14 is provided inside the fine grinding seat 13. The fine grinding drill bit 16 is arranged inside the grinding cone 14, and the inclination of the outer wall inclined surface of the fine grinding drill bit 16 is greater than the inclination of the inner wall inclined surface of the grinding cone 14, so that the gap between the fine grinding drill bit 16 and the grinding cone 14 gradually decreases, so that the sample is ground more and more finely, and a discharge cone 15 is provided at the top of the fine grinding seat 13. The discharge cone 15 is set to a concave surface with a lower inner side and a higher outer side, so that the sample falling on the discharge cone 15 slides along the inclined surface into the grinding cone 14, and the bottom of the fine grinding seat 13 is fixedly connected with a discharge port 17 for convenient discharge of high-grinding degree samples after grinding.

[0033] Working principle: When the sample required for the molecular biology experiment is coarsely ground for the first time, the sample is put into the feeding port 3. At this time, part of the sample falls on the grinding teeth, and some falls on the unloading table 12. The rotating motor 5 is turned on, and the rotating motor 5 drives the grinding wheel 7 and the unloading table 12 to rotate. At this time, the unloading table 12 will cause the sample to move outward due to the action of centrifugal force and gravity, and enter the gap between the inner grinding teeth 8 and the outer grinding teeth 10, and be crushed and ground. Some samples will enter the gap between the outer grinding teeth 10. At this time, the sample falls and falls on the outer retaining ring 11, and falls along the inclined surface of the outer retaining ring 11. At this time, the sample will be crushed by the inner grinding teeth 8. At the same time, some samples will fall onto the inner retaining ring 9, and then fall from the inclined surface of the inner retaining ring 9 and be crushed by the outer grinding teeth 10, thereby preventing the sample from falling along the gap and being unable to be fully ground. After the sample is roughly ground for the first time, it falls directly onto the discharge cone 15 and moves toward the center along the inclined surface. At this time, the sample falls into the grinding cone 14 and is finely ground for the second time by the fine-grinding drill bit 16 and the grinding cone 14. This eliminates the need to transfer the sample, ensuring that the sample will not be lost or denatured during the transfer process, thereby ensuring the accuracy of the experiment.

[0034] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A grinding device for molecular biology experiments, comprising a fixed base (1), characterized in that: The front of the fixed base (1) is fixedly connected to a grinding jar (2), a feeding port (3) is provided at the top of the grinding jar (2), a power assembly is provided at the top of the grinding jar (2), the power assembly is used to provide grinding power, the bottom of the power assembly is fixedly connected to a rotating shaft (6), the outer peripheral surface of the rotating shaft (6) is fixedly connected to a grinding wheel (7), the bottom of the rotating shaft (6) is fixedly connected to a fine grinding drill (16), the outer peripheral surface of the grinding wheel (7) is fixedly connected to an inner grinding tooth (8), the inner part of the inner grinding tooth (8) is fixedly connected to an inner retaining ring (9), the inner wall of the side of the grinding jar (2) is fixedly connected to an outer grinding tooth (10), the inner part of the outer grinding tooth (10) is fixedly connected to an outer retaining ring (11), the top of the grinding wheel (7) is fixedly connected to a feeding table (12), the bottom of the grinding jar (2) is detachably connected to a fine grinding assembly, and the fine grinding assembly is used to perform secondary fine grinding on the material.

2. A grinding device for molecular biology experiments according to claim 1, characterized in that: The fine grinding assembly comprises a fine grinding seat (13), the outer peripheral surface of the fine grinding seat (13) is detachably connected to the lower inner portion of the grinding tank (2), a grinding cone surface (14) is provided inside the fine grinding seat (13), a discharge cone surface (15) is provided at the top end of the fine grinding seat (13), and a discharge port (17) is fixedly connected to the bottom of the fine grinding seat (13).

3. The grinding device for molecular biology experiments according to claim 1, characterized in that: The power assembly comprises a motor bracket (4), the bottom end of the motor bracket (4) is fixedly connected to the top end of the grinding jar (2), a rotating motor (5) is fixedly connected inside the motor bracket (4), and the top end of the rotating shaft (6) is fixedly connected to the output shaft at the bottom end of the rotating motor (5).

4. The grinding device for molecular biology experiments according to claim 1, characterized in that: The outer circumference of the rotating shaft (6) is rotatably connected to the interior of the grinding jar (2), and the interior of the blanking table (12) is fixedly connected to the outer circumference of the rotating shaft (6).

5. The grinding device for molecular biology experiments according to claim 1, characterized in that: The inner side of the inner retaining ring (9) is fixedly connected to the outer peripheral surface of the grinding wheel (7), and the inner and outer sides of the outer retaining ring (11) are fixedly connected to the inner wall of the grinding tank (2).

6. The grinding device for molecular biology experiments according to claim 1, characterized in that: The outer side of the inner retaining ring (9) is set as an inclined surface, and the inner side of the outer retaining ring (11) is set as an inclined surface. The inner retaining ring (9) and the outer retaining ring (11) are alternately arranged from top to bottom and are not in the same horizontal plane.

7. The grinding device for molecular biology experiments according to claim 1, characterized in that: The fine grinding drill bit (16) is arranged inside the grinding cone surface (14), and the slope of the outer wall of the fine grinding drill bit (16) is greater than the slope of the inner wall of the grinding cone surface (14).

8. The grinding device for molecular biology experiments according to claim 2, characterized in that: The blanking conical surface (15) is configured as a concave surface with a lower inner side and a higher outer side.