Ketoconazole cream emulsifying device
By designing the ketoconazole cream emulsification device and using an efficient stirring system and a scraping rack, the problems of uneven mixing and poor stability of the ketoconazole cream are solved, and the efficient and uniform mixing and purity of the cream are achieved.
Patent Information
- Application Number
- CN202422574953.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-24
- Publication Date
- 2025-09-02
- Estimated Expiration
- 2034-10-24
AI Technical Summary
The emulsification process of existing ketoconazole creams is time-consuming and labor-intensive, and the mixing is uneven and prone to problems such as graininess or poor stability.
A ketoconazole cream emulsification device is designed, which includes a high-efficiency stirring system, heating tank angle adjustment, foam scraping rack and filter screen. Through the combination of the stirring paddle and foam scraping rack, it ensures that the oil and water phase components are evenly mixed, and effectively removes foam and impurities.
It achieves efficient and even mixing of ketoconazole cream, improves the purity and stability of the cream, reduces manual intervention, and ensures consistency of production.
Smart Images
Figure CN223287964U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of pharmaceutical product emulsification, in particular to a ketoconazole cream emulsification device. Background Art
[0002] Ketoconazole cream is a topical antifungal medication used primarily to treat skin infections caused by fungi.
[0003] In the pharmaceutical industry, emulsification is a key step that directly affects the quality of the final product, including the stability, uniformity and absorption effect of the cream.
[0004] In the process of ketoconazole cream in some small enterprises, operators usually need to constantly stir the raw materials and manually adjust the angle of the heating tank to ensure uniform mixing. This method is not only time-consuming and labor-intensive, but also difficult to ensure consistency in each production. In some cases, due to uneven mixing or failure to eliminate foam in time, some finished products may have problems such as graininess or poor stability.
[0005] Therefore, a ketoconazole cream emulsifying device should be proposed urgently. Utility Model Content
[0006] In order to overcome the above-mentioned shortcomings of the prior art, the utility model provides a ketoconazole cream emulsifying device.
[0007] In order to solve the above technical problems, the utility model provides a ketoconazole cream emulsifying device, comprising an organic base, a fixed ring, a heating tank, a top plate, an assembly frame, a first motor, a second bevel gear, a third bevel gear, a stirring paddle, a defoaming group, an electromagnetic valve and a rotation group, wherein two support rods are provided on the upper part of the base, a fixed ring is rotatably provided between the two support rods of the base, a heating tank is provided on the inner side of the fixed ring, a top plate is provided on the top of the heating tank, an assembly frame is provided on the rear side of the top of the top plate, a first motor is provided on the top of the assembly frame, a second bevel gear is rotatably provided at the center of the top of the top plate, a third bevel gear is provided on the output shaft of the first motor, a stirring paddle is provided at the bottom of the third bevel gear, the stirring paddle is located in the middle of the heating tank, the third bevel gear is rotatably engaged with the second bevel gear below, a convex rod is provided on the outside of the first motor, a defoaming group for defoaming the raw material is provided in the heating tank, a electromagnetic valve is provided at the center of the bottom of the heating tank, and a rotation group for driving the fixed ring to rotate is provided on one of the rods of the base.
[0008] Preferably, the defoaming group includes a first bevel gear, a scraper frame and a filter screen. The first bevel gear is rotatably provided on the protruding rod outside the first motor. The first bevel gear is rotatably engaged with the third bevel gear below. A scraper frame is provided at the bottom of the first bevel gear. The horizontal bar in the middle of the scraper frame rotates and passes through the middle of the stirring paddle. Both sides of the scraper frame are in rotational contact with the inner wall of the heating tank. The scraper frame as a whole forms an elliptical shape that adapts to the inner cross-section of the heating tank. Filter screens are embedded on both sides of the scraper frame.
[0009] Preferably, the blades of the stirring paddle are located in the middle surrounded by the scraper frame.
[0010] Preferably, a downwardly protruding pipe opening is provided in the center of the bottom of the heating tank.
[0011] Preferably, a spiral rod is further included. The spiral rod is arranged at the center of the bottom of the foam scraper frame, and the spiral rod is located in the pipe opening at the bottom of the heating tank.
[0012] Preferably, the rotation group includes a second motor, a worm and a worm wheel. The second motor is provided on one of the support rods of the machine base, the worm is provided on the output shaft of the second motor, and a worm wheel is provided on one side of the connecting shaft of the fixing ring. The worm wheel is rotatably engaged with the worm wheel below.
[0013] Beneficial effects: The efficient stirring system and the angle adjustment of the heating tank ensure uniform mixing of the oil and water phase components; the scraper and filter design effectively remove foam and impurities, improve the purity of the cream, and reduce the need for manual intervention. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model.
[0015] Figure 2 It is a three-dimensional structural cross-sectional diagram of the heating tank, top plate, assembly frame and other components of the utility model.
[0016] Figure 3 It is a three-dimensional structural diagram of the first motor, stirring paddle, scraper and other components of the utility model.
[0017] Figure 4 It is a three-dimensional structural diagram of the second motor, worm and worm wheel components of the utility model.
[0018] The marks in the accompanying drawings are: 1-base, 101-fixed ring, 2-heating tank, 3-top plate, 4-assembly frame, 5-first motor, 51-first bevel gear, 52-second bevel gear, 62-third bevel gear, 7-stirring paddle, 8-scraper rack, 9-filter, 10-screw rod, 11-solenoid valve, 12-second motor, 13-worm, 14-worm gear. DETAILED DESCRIPTION
[0019] The present invention will be further described below with reference to the accompanying drawings and embodiments.
[0020] Embodiment: A ketoconazole cream emulsifying device, such as Figures 1-4 As shown, it includes an organic base 1, a fixed ring 101, a heating tank 2, a top plate 3, an assembly frame 4, a first motor 5, a second bevel gear 52, a third bevel gear 62, a stirring paddle 7, a defoaming group, a solenoid valve 11 and a switching group. The base 1 provides the basic support structure of the entire emulsification device to ensure that the relative positions of the various components are fixed and to facilitate the assembly and maintenance of the entire device. Two support rods are provided on the upper part of the base 1. A fixed ring 101 is rotatably provided between the two support rods of the base 1. The fixed ring 101 supports the heating tank 2 and allows it to rotate relative to the base 1. The heating tank 2 is provided on the inner side of the fixed ring 101. The worm 13 and the worm gear 14 driven by the second motor 12 realize the rotation of the heating tank 2, thereby improving the mixing effect. The heating tank 2 is used to accommodate various raw materials in the emulsification process and maintain a constant temperature by heating to facilitate the emulsification reaction. A downwardly protruding pipe port is provided in the center of the bottom of the heating tank 2. A top plate 3 is provided on the top of the tank 2, and an assembly frame 4 is provided on the rear side of the top of the top plate 3. A first motor 5 is provided on the top of the assembly frame 4. The first motor 5 provides a power source, and drives the stirring paddle 7 to rotate through the third bevel gear 62. A second bevel gear 52 is provided at the center of the top of the top plate 3. A third bevel gear 62 is provided on the output shaft of the first motor 5, and a stirring paddle 7 is provided at the bottom of the third bevel gear 62. The stirring paddle 7 is located in the middle of the heating tank 2, and the third bevel gear 62 is rotatably engaged with the second bevel gear 52 below, transmitting the rotational power from the first motor 5 to the stirring paddle 7. A convex rod is provided on the outside of the first motor 5, and a defoaming group for defoaming the raw materials is provided in the heating tank 2. An electromagnetic valve 11 is provided at the center of the bottom of the heating tank 2 for controlling the discharge of the emulsified cream. It is opened and closed by the control system to ensure that the cream flows out smoothly without leaking. One of the rods of the machine base 1 is provided with a switching group that drives the fixing ring 101 to rotate.
[0021] like Figure 1-Figure 3As shown, the defoaming group includes a first bevel gear 51, a scraper frame 8 and a filter screen 9. The first bevel gear 51 is rotatably provided on the convex rod outside the first motor 5, and the first bevel gear 51 is rotatably engaged with the third bevel gear 62 below. When the first bevel gear 51 rotates, the scraper frame 8 is driven to remove the foam on the inner wall of the heating tank 2. The scraper frame 8 is provided at the bottom of the first bevel gear 51. The horizontal bar in the middle of the scraper frame 8 rotates and passes through the middle of the stirring paddle 7. The blade of the stirring paddle 7 is located in the middle surrounded by the scraper frame 8. The stirring paddle 7 is driven to rotate by the rotation of the third bevel gear 62, so that the oil phase components are evenly distributed and preliminarily mixed with the water phase components. Both sides of the scraper frame 8 are in rotational contact with the inner wall of the heating tank 2. The scraper frame 8 is formed into an elliptical shape that adapts to the inner cross-section of the heating tank 2. The filter screen 9 is embedded on both sides of the scraper frame 8. When the scraper frame 8 rotates, the foam on the inner wall of the heating tank 2 can be removed and impurities can be filtered through the filter screen 9 to maintain the purity of the cream.
[0022] like Figure 2-Figure 3 As shown, a spiral rod 10 is also included. The spiral rod 10 is arranged at the center of the bottom of the scraper frame 8. The spiral rod 10 is located in the pipe opening at the bottom of the heating tank 2. When the spiral rod 10 rotates, it helps to discharge the emulsified cream.
[0023] like Figure 1 and Figure 4 As shown, the turning group includes a second motor 12, a worm 13 and a worm gear 14. The second motor 12 is provided on one of the support rods of the machine base 1, the worm 13 is provided on the output shaft of the second motor 12, and a worm gear 14 is provided on one side of the connecting shaft of the fixing ring 101. The worm gear 14 receives the rotational power from the second motor 12 to rotate the fixing ring 101 and the heating tank 2.
[0024] First, various required raw materials (including ketoconazole powder, matrix components such as white vaseline, lanolin, stearic acid, etc., and aqueous phase components such as deionized water, glycerin, etc.) are prepared according to the formula ratio and preheated to a suitable temperature. At this time, the heating tank 2 is in an idle state. It is necessary to first adjust the heating tank 2 to a position convenient for adding materials, start the second motor 12, and the worm 13 on its output shaft drives the worm gear 14 on the fixed ring 101 to rotate, so that the fixed ring 101 rotates together with the heating tank 2. By adjusting the angle of the heating tank 2 so that its opening faces upward, it is convenient to dock the delivery pipe. After the heating tank 2 is adjusted to its position, the delivery pipe is aligned with the heating tank 2. Connect to the top opening of the heating tank 2, start adding the preheated oil phase components, and after the oil phase components are added, add the preheated water phase components through the delivery pipe. At this time, all the required raw materials have been loaded inside the heating tank 2. Close the external delivery pipe, start the first motor 5, and its output shaft drives the third bevel gear 62 to rotate. The third bevel gear 62 engages with the second bevel gear 52 above, so that the second bevel gear 52 rotates, and then drives the stirring paddle 7 to rotate. The stirring paddle 7 is located in the middle of the heating tank 2. Its rotation can promote the uniform distribution of the oil phase components and preliminarily mix them with the water phase components. At the same time, the heating tank 2 starts to heat to ensure the mixing During the process, the temperature is kept constant. At the same time, the first bevel gear 51 is driven by the third bevel gear 62 below and meshes with it, so that the foam scraping frame 8 rotates with the first bevel gear 51. The foam scraping frame 8 is elliptical, and its two sides are in contact with the inner wall of the heating tank 2, which can remove the foam on the inner wall of the tank body and filter out impurities through the filter screen 9 on the inner side of the foam scraping frame 8. The filter screen 9 can capture impurities in the foam to ensure the purity of the cream. During the mixing process, in order to further improve the uniformity of the mixing, the second motor 12 can be started again, and the heating tank 2 can be rotated through the cooperation of the worm 13 and the worm gear 14 to change the angle of the tank body to ensure more uniform mixing. Evenly mix to prevent insufficient mixing in some parts. When all the ingredients are fully mixed and emulsified, turn off the first motor 5 and the second motor 12, stop stirring and rotating the heating tank 2. At this time, the cream has been basically formed and can be discharged through the electromagnetic valve 11 at the bottom of the heating tank 2. The opening of the electromagnetic valve 11 can be achieved by the control system to ensure that the cream can flow out smoothly without leakage. After each emulsification is completed, the heating tank 2 needs to be thoroughly cleaned to prevent residual substances from affecting the next production. At the same time, regularly check whether the stirring paddle 7, scraper rack 8, filter screen 9 and other components are worn or blocked to ensure that the equipment is always in the best working condition.
[0025] The above-described embodiments merely represent preferred embodiments of the present invention. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the present invention. It should be noted that a person skilled in the art would be able to make various modifications, improvements, and substitutions without departing from the concept of the present invention, all of which fall within the scope of protection of the present invention. Therefore, the scope of protection of the present invention shall be determined by the appended claims.
Claims
1. A ketoconazole cream emulsifying device, characterized in that, The invention comprises an organic base (1), a fixing ring (101), a heating tank (2), a top plate (3), an assembly frame (4), a first motor (5), a second bevel gear (52), a third bevel gear (62), a stirring paddle (7), a defoaming group, a solenoid valve (11) and a turning group, wherein two supporting rods are provided on the upper part of the organic base (1), a fixing ring (101) is rotatably provided between the two supporting rods of the organic base (1), a heating tank (2) is provided on the inner side of the fixing ring (101), a top plate (3) is provided on the top of the heating tank (2), an assembly frame (4) is provided on the rear side of the top of the top plate (3), a first motor (5) is provided on the top of the assembly frame (4), and a top plate (3) is provided on the top of the organic base (1). A second bevel gear (52) is rotatably provided at the center of the first motor (5), a third bevel gear (62) is provided on the output shaft of the first motor (5), a stirring paddle (7) is provided at the bottom of the third bevel gear (62), the stirring paddle (7) is located in the middle of the heating tank (2), the third bevel gear (62) is rotatably engaged with the second bevel gear (52) below, a convex rod is provided on the outside of the first motor (5), a defoaming group for defoaming the raw materials is provided in the heating tank (2), a solenoid valve (11) is provided at the center of the bottom of the heating tank (2), and a rotation group for driving the fixed ring (101) to rotate is provided on one of the rods of the machine base (1).
2. A ketoconazole cream emulsifying device according to claim 1, characterized in that, The defoaming group comprises a first bevel gear (51), a foam scraper (8) and a filter (9); the first bevel gear (51) is rotatably provided on the protruding rod outside the first motor (5); the first bevel gear (51) is rotatably engaged with the third bevel gear (62) below; a foam scraper (8) is provided at the bottom of the first bevel gear (51); a horizontal bar in the middle of the foam scraper (8) rotates and passes through the middle of the stirring paddle (7); both sides of the foam scraper (8) are in rotational contact with the inner wall of the heating tank (2); the foam scraper (8) as a whole forms an elliptical shape adapted to the inner cross-section of the heating tank (2); and the filter (9) is embedded in both sides of the foam scraper (8).
3. A ketoconazole cream emulsifying device according to claim 2, characterized in that, The blades of the stirring paddle (7) are located in the middle surrounded by the scraper frame (8).
4. A ketoconazole cream emulsifying device according to claim 3, characterized in that, A downwardly protruding pipe opening is provided at the center of the bottom of the heating tank (2).
5. A ketoconazole cream emulsifying device according to claim 4, characterized in that, It also includes a spiral rod (10), which is arranged at the center of the bottom of the foam scraper frame (8), and the spiral rod (10) is located in the pipe opening at the bottom of the heating tank (2).
6. A ketoconazole cream emulsifying device according to claim 5, characterized in that, The turning group includes a second motor (12), a worm (13) and a worm wheel (14); the second motor (12) is provided on one of the support rods of the machine base (1); the worm (13) is provided on the output shaft of the second motor (12); a worm wheel (14) is provided on one side of the connecting shaft of the fixing ring (101); the worm wheel (14) is rotatably engaged with the worm (13) below.