Protein spectrum pretreatment desalting device

Abstract

The utility model belongs to the technical field of protein spectrums, and particularly relates to a protein spectrum pretreatment desalting device which comprises a box body, the placing disc is arranged at the top of the inner cavity of the box body, placing holes are formed in the top of the placing disc, and the number of the placing holes is six; the rotating rod is fixedly mounted at the bottom of the placing disc; the bottom of the rotating rod is fixedly connected with the output of the first motor; the bottom of the first motor is fixedly connected with the fixing plate, and the front side and the rear side of the fixing plate are fixedly connected with the inner wall of the box body; the material jacking mechanism is located at the bottom of the inner cavity of the box body, the material jacking mechanism is used for jacking the centrifugal tube, the material jacking mechanism comprises a second motor, a threaded rod, a threaded sleeve, a connecting rod and a lifting disc, the centrifugal tube can be conveniently taken by an experimenter through matched use of the material jacking mechanism, and the experiment efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of protein spectrum, in particular to a protein spectrum pre-treatment desalination device. Background Art

[0002] Desalting before protein spectrometry refers to the removal of salts and other ionic substances that may affect mass spectrometry analysis in the sample before mass spectrometry analysis. This is because the presence of salts may interfere with the performance of the mass spectrometer, especially in terms of the sensitivity and resolution of mass spectrometry analysis. The desalting device in protein spectrometry pretreatment usually refers to the equipment or method used to remove salts and other ionic substances in the sample. These devices are designed to reduce the interference that may be caused during mass spectrometry analysis.

[0003] In conventional desalting prior to protein profiling, a desalting column is generally placed in a centrifuge tube, which is then placed in a centrifuge for desalting. However, since the centrifuge tube fits tightly into the placement slot of the centrifuge, it is inconvenient to remove the centrifuge tube, which reduces experimental efficiency. Therefore, the present invention proposes a protein profiling pretreatment desalting device to address the above-mentioned problem. Utility Model Content

[0004] The purpose of the utility model is to solve the problem in the prior art that desalting before protein spectrum is generally performed by placing a desalting column in a centrifuge tube, and the centrifuge tube is placed in a centrifuge for desalting. Since the centrifuge tube fits tightly with the placement slot of the centrifuge, it is inconvenient to take the centrifuge tube, which reduces the experimental efficiency. A protein spectrum pretreatment desalting device is proposed.

[0005] In order to achieve the above purpose, the present invention adopts the following technical solutions:

[0006] A protein spectrum pretreatment desalting device, comprising:

[0007] Box;

[0008] A placement tray is provided at the top of the inner cavity of the box, and six placement holes are provided on the top of the placement tray;

[0009] A rotating rod, the rotating rod being fixedly mounted on the bottom of the placement tray;

[0010] The first motor and the bottom of the rotating rod are fixedly connected to the output of the first motor;

[0011] A fixing plate, wherein the bottom of the first motor is fixedly connected to the fixing plate, and the front and rear sides of the fixing plate are fixedly connected to the inner wall of the box;

[0012] The lifting mechanism is located at the bottom of the inner cavity of the box and is used to lift the centrifuge tube.

[0013] As a preferred solution of the present invention, the ejecting mechanism includes: a second motor, a threaded rod, a threaded sleeve, a connecting rod and a lifting plate;

[0014] The second motor is fixedly installed at the bottom of the inner cavity of the box, and the output ends on both sides of the second motor are fixedly connected to the threaded rods. The opposite sides of the two threaded rods are rotatably connected to the inner wall of the box through a rotating shaft. There are two threaded sleeves, and the two threaded sleeves are movably sleeved on the surfaces of the two threaded rods. The top of the threaded sleeve is fixedly connected to the connecting rod. There are two connecting rods. The lifting plate is movably arranged in the inner cavity of the box and is located at the top of the connecting rod. Both sides of the bottom of the lifting plate are fixedly connected to the top of the connecting rod.

[0015] As a preferred solution of the present invention, a controller is fixedly connected to the front side of the box.

[0016] As a preferred solution of the present invention, the four corners of the bottom of the box are fixedly connected with support legs.

[0017] As a preferred solution of the present invention, a circular hole is opened on the top of the lifting plate, and a circular array of rubber pads is arranged on the top of the lifting plate, and the number of the rubber pads is six.

[0018] As a preferred solution of the present invention, the bottom of the front and rear sides of the connecting rod are fixedly connected with sliding sleeves, there are four sliding sleeves, the inner cavity of the sliding sleeve is slidably connected with sliding rods, there are two sliding rods, and both sides of the sliding rods are fixedly connected to the inner wall of the box.

[0019] Beneficial effects:

[0020] 1. By turning on the second motor to drive the threaded rod to rotate, the threaded rod drives the threaded sleeve and the connecting rod to move, and the connecting rod drives the lifting plate to move. When the lifting plate moves, the centrifuge tube can be lifted, making it convenient for the experimenter to take the centrifuge tube;

[0021] In the utility model, the coordinated use of the lifting mechanism can facilitate the experimenter to take the centrifuge tube, thereby improving the efficiency of the experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a structural diagram of the utility model;

[0023] Figure 2 This is a cross-sectional view of the box body of the present utility model;

[0024] Figure 3 This is a schematic diagram of the structure of the second motor and the lifting plate of the utility model;

[0025] Figure 4 For the utility model Figure 3 A magnified view of the middle panel.

[0026] In the figure: 1. Box body; 2. Placement plate; 3. Rotating rod; 4. First motor; 5. Fixed plate; 6. Second motor; 7. Threaded rod; 8. Threaded sleeve; 9. Connecting rod; 10. Lifting plate; 11. Controller; 12. Support leg; 13. Rubber pad; 14. Sliding sleeve; 15. Sliding rod. DETAILED DESCRIPTION

[0027] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0028] Example

[0029] Reference Figures 1-4 , a protein spectrum pre-treatment desalting device, comprising:

[0030] Box 1;

[0031] The placing tray 2 is arranged at the top of the inner cavity of the box body 1. The placing tray 2 has six placing holes on the top;

[0032] The rotating rod 3 is fixedly installed at the bottom of the placement tray 2;

[0033] The first motor 4 and the bottom of the rotating rod 3 are fixedly connected to the output of the first motor 4;

[0034] A fixing plate 5, the bottom of the first motor 4 is fixedly connected to the fixing plate 5, and the front and rear sides of the fixing plate 5 are fixedly connected to the inner wall of the box body 1;

[0035] The lifting mechanism is located at the bottom of the inner cavity of the box body 1 and is used to lift the centrifuge tube.

[0036] As a preferred solution of the present invention, the ejecting mechanism includes: a second motor 6, a threaded rod 7, a threaded sleeve 8, a connecting rod 9 and a lifting plate 10;

[0037] The second motor 6 is fixedly installed at the bottom of the inner cavity of the box body 1, and the output ends on both sides of the second motor 6 are fixedly connected to the threaded rod 7. The opposite sides of the two threaded rods 7 are rotatably connected to the inner wall of the box body 1 through a rotating shaft. There are two threaded sleeves 8, and the two threaded sleeves 8 are movably sleeved on the surfaces of the two threaded rods 7. The top of the threaded sleeve 8 is fixedly connected to the connecting rod 9. There are two connecting rods 9. The lifting plate 10 is movably arranged in the inner cavity of the box body 1 and is located at the top of the connecting rod 9. Both sides of the bottom of the lifting plate 10 are fixedly connected to the top of the connecting rod 9. By turning on the second motor 6 to drive the threaded rod 7 to rotate, the threaded rod 7 drives the threaded sleeve 8 and the connecting rod 9 to move, and the connecting rod 9 drives the lifting plate 10 to move. When the lifting plate 10 moves, the centrifuge tube can be lifted, which makes it convenient for the experimenter to take the centrifuge tube.

[0038] As a preferred solution of the present invention, a controller 11 is fixedly connected to the front side of the box 1. The controller 11 can facilitate the desalination work of the experimenter, and the rotation speed and time can be adjusted by the controller 11.

[0039] As a preferred solution of the present invention, the four corners of the bottom of the box body 1 are fixedly connected with support legs 12. By providing the support legs 12, the stability of the box body 1 can be improved.

[0040] As a preferred solution of the present invention, a circular hole is provided on the top of the lifting plate 10, and a circular array of rubber pads 13 is provided on the top of the lifting plate 10. The number of rubber pads 13 is six. By providing the circular hole, the lifting plate 10 can be easily lifted and lowered to avoid contact with the second motor 6. By providing the rubber pads 13, the lifting plate 10 can be in soft contact with the centrifuge tube.

[0041] As a preferred solution of the present invention, the bottom of the front and rear sides of the connecting rod 9 are fixedly connected with a sliding sleeve 14, and the number of the sliding sleeve 14 is four. The inner cavity of the sliding sleeve 14 is slidably connected with a sliding rod 15, and the number of the sliding rod 15 is two. Both sides of the sliding rod 15 are fixedly connected to the inner wall of the box body 1. By setting the sliding sleeve 14 and the sliding rod 15 for use in conjunction, the stability of the connecting rod 9 and the threaded sleeve 8 during movement can be improved.

[0042] By means of the above structure, the use of the lifting mechanism can facilitate the experimenter to take the centrifuge tube, thereby improving the efficiency of the experiment.

[0043] It should be noted that the specific types of motors and controllers 11 to be used are selected by relevant technical personnel familiar with the field, and the above motors and controllers 11 are all existing technologies and will not be elaborated in this solution.

[0044] The working principle of the present invention is as follows: when in use, the experimenter places the centrifuge tube equipped with the desalting column into the placement hole, and then turns on the first motor 4, which drives the placement plate 2 to rotate, and the placement plate 2 drives the centrifuge tube to rotate, so that desalting work can be carried out. When the centrifuge tube needs to be taken, the second motor 6 is turned on to drive the threaded rod 7 to rotate, and the threaded rod 7 drives the threaded sleeve 8 and the connecting rod 9 to move, and the connecting rod 9 drives the lifting plate 10 to move. When the lifting plate 10 moves, the centrifuge tube can be lifted, which makes it convenient for the experimenter to take the centrifuge tube and improves the efficiency of the experiment.

[0045] The above is only a preferred specific implementation method of the present invention, but the protection scope of the present invention is not limited to this. Any technician familiar with the technical field within the technical scope disclosed by the present invention can make equivalent replacements or changes based on the technical solution and utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A protein spectrum pretreatment desalting device, characterized in that: include: Box (1); A placement tray (2), the placement tray (2) being arranged at the top of the inner cavity of the box body (1), and having placement holes on the top of the placement tray (2), with six placement holes in number; A rotating rod (3), wherein the rotating rod (3) is fixedly mounted on the bottom of the placement plate (2); The first motor (4) and the bottom of the rotating rod (3) are fixedly connected to the output of the first motor (4); A fixing plate (5), the bottom of the first motor (4) is fixedly connected to the fixing plate (5), and the front and rear sides of the fixing plate (5) are fixedly connected to the inner wall of the box body (1); The lifting mechanism is located at the bottom of the inner cavity of the box body (1) and is used to lift the centrifuge tube. The ejecting mechanism comprises: a second motor (6), a threaded rod (7), a threaded sleeve (8), a connecting rod (9) and a lifting plate (10); The second motor (6) is fixedly mounted on the bottom of the inner cavity of the box body (1); the output ends on both sides of the second motor (6) are fixedly connected to the threaded rod (7); the opposite sides of the two threaded rods (7) are rotatably connected to the inner wall of the box body (1) through a rotating shaft; there are two threaded sleeves (8); the two threaded sleeves (8) are movably sleeved on the surfaces of the two threaded rods (7); the tops of the threaded sleeves (8) are fixedly connected to the connecting rod (9); there are two connecting rods (9); a lifting plate (10) is movably arranged in the inner cavity of the box body (1) and is located on the top of the connecting rod (9); both sides of the bottom of the lifting plate (10) are fixedly connected to the top of the connecting rod (9).

2. A protein spectrum pretreatment desalination device according to claim 1, characterized in that: The front side of the box (1) is fixedly connected with a controller (11).

3. The protein spectrum pretreatment desalination device according to claim 1, characterized in that: The four corners of the bottom of the box body (1) are fixedly connected with support legs (12).

4. The protein spectrum pretreatment desalination device according to claim 1, characterized in that: A circular hole is provided on the top of the lifting plate (10), and a circular array of rubber pads (13) is provided on the top of the lifting plate (10), and the number of the rubber pads (13) is six.

5. The protein spectrum pretreatment desalination device according to claim 1, characterized in that: The bottom of the front and rear sides of the connecting rod (9) are fixedly connected with sliding sleeves (14), the number of the sliding sleeves (14) is four, the inner cavity of the sliding sleeves (14) is slidably connected with sliding rods (15), the number of the sliding rods (15) is two, and both sides of the sliding rods (15) are fixedly connected to the inner wall of the box body (1).

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