Solid-phase extraction device with cleaning structure

Abstract

The solid-phase extraction device with the cleaning structure comprises a base, a supporting frame is arranged at the top end of the base, and a lifting plate is connected into the supporting frame in a sliding mode; a moving mechanism is arranged at the top end of the base, and an adjusting assembly is arranged on one side of the supporting frame. Wherein the moving mechanism comprises a moving plate slidably connected to the interior of the top end of the base, supporting plates are symmetrically installed on the two sides of the top end of the moving plate, supports are symmetrically slidably connected to the interior of the top end of the moving plate, fixing seats are symmetrically installed at the top end of the base, and rotating plates are rotatably connected to the interiors of the fixing seats; therefore, the effect of rapidly adjusting and switching the collecting pipe can be achieved, the effect of cleaning waste liquid while solid-phase extraction in the liquid can be achieved, the solid-phase extraction efficiency in the liquid is greatly improved, the cleaning speed of the collecting pipe can be further improved, and the phenomenon that the use efficiency of the device is affected due to operation conflict of the two is avoided.

Description

Technical Field

[0001] This utility model relates to the technical field of solid phase extraction devices, specifically a solid phase extraction device with a cleaning structure. Background Technology

[0002] Solid-phase extraction (SPE) is a sample pretreatment technique that has been developed in recent years. It is derived from the combination of liquid-solid extraction columns and liquid chromatography. It is mainly used for the separation, purification and concentration of samples. Currently, solid-phase extraction equipment is required when performing solid-phase extraction.

[0003] Publication No. CN220360742U discloses a solid-phase extraction device. This device connects multiple sets of extraction columns at the top of multiple sets of first valves. Rinse liquid is placed into a conveying device and discharged into the extraction columns. By opening the multiple sets of first valves, the rinsing liquid in the extraction columns is discharged downwards, thus rinsing and cleaning the columns. Waste liquid generated during rinsing is collected by a collection device. After rinsing, the liquid sample is discharged into the extraction columns via the conveying device, allowing the extraction columns to perform solid-phase extraction on the liquid. The eluted sample is collected by the collection device, improving the convenience of collecting different liquids. However, this patent still has the following problems in practical use:

[0004] The device discharges liquid into the extraction columns via a conveying device. By opening multiple sets of first valves, the rinsing liquid inside the extraction columns is discharged downwards, thereby rinsing and cleaning the extraction columns. The waste liquid generated during rinsing is collected by a collection device. However, when cleaning the waste liquid inside the collection tubes, the operator needs to slide the positioning plate and the second frame on the guide rail to remove all the collection tubes for cleaning and reinstallation. This greatly reduces the solid-phase extraction efficiency of the device and makes it impossible to quickly switch the collection tubes, causing inconvenience to the operator.

[0005] A solid-phase extraction apparatus with a cleaning structure is proposed to address the problems mentioned above. Utility Model Content

[0006] The purpose of this invention is to provide a solid-phase extraction device with a cleaning structure to solve the problems mentioned in the background art. Currently, the device discharges liquid into the extraction column through a conveying device, and opens multiple sets of first valves to discharge the rinsing liquid from the extraction column downwards, thereby rinsing and cleaning the extraction column. The waste liquid generated during rinsing is collected by a collection device. However, when cleaning the waste liquid inside the collection tube, the operator needs to slide the positioning plate and the second frame on the guide rail to remove, clean, and reinstall all the collection tubes, which greatly reduces the solid-phase extraction efficiency of the device and makes it impossible to quickly switch the collection tubes, causing inconvenience to the operator.

[0007] To achieve the above objectives, the present invention provides the following technical solution: a solid-phase extraction device with a cleaning structure, comprising a base, a support frame at the top of the base, and a lifting plate slidably connected inside the support frame; a moving mechanism at the top of the base, and an adjustment component on one side of the support frame;

[0008] The moving mechanism includes a movable plate slidably connected to the inside of the top of the base, with support plates symmetrically installed on both sides of the top of the movable plate, and brackets symmetrically slidably connected to the inside of the top of the movable plate. A fixed seat is symmetrically installed on the top of the base, and a rotating plate is rotatably connected inside the fixed seat. One side of the top of the rotating plate is fastened to the support plate. A fixed box is installed on one side of the top of the rotating plate, and a sliding rod is slidably connected inside the bottom of the fixed box. A first telescopic spring is sleeved on the outer side of the bottom of the sliding rod. A push plate is slidably connected inside one end of the fixed box, and inserts are installed on one side of the push plate, with the inserts plugging into the support plate. A movable rod is rotatably connected to one side of the top of the sliding rod, and one end of the movable rod is rotatably connected to the push plate.

[0009] Preferably, the top of each movable plate is symmetrically equipped with a fixed frame, and the two ends of the fixed frame are symmetrically provided with mounting grooves. A fixed rod is installed inside the mounting groove, and a sliding sleeve is slidably connected to the outside of the fixed rod. A second telescopic spring is sleeved on the outside of the fixed rod, and a sliding plate is installed between the sliding sleeves. An insert plate is installed on one side of each sliding plate, and slots are symmetrically provided on both sides of the bottom end of the bracket. The insert plate is inserted into the slot.

[0010] Preferably, the adjusting assembly includes a sliding box fixedly connected to one side of the support frame, a connecting box installed at the top of the sliding box, a square rod slidably connected inside the sliding box, a screw rotatably connected between the sliding box and the connecting box, the square rod being threadedly connected to the outer side of the bottom end of the screw, a worm gear rotatably connected inside the connecting box, a worm wheel installed on the outer side of the top end of the screw, a pointer installed on one side of the bottom end of the sliding box, scale lines opened on one side of the square rod, a connecting block installed at the bottom end of the square rod, and one end of the lifting plate being fixedly connected to the connecting block.

[0011] Preferably, support blocks are symmetrically installed on one side of the support frame, and support rods are installed between the support blocks. A slider is slidably connected to the outside of the support rod, and one end of the lifting plate is fixedly connected to the slider.

[0012] Preferably, the top of the bracket is provided with slots.

[0013] Preferably, the sliding sleeve is located inside the mounting groove for sliding connection.

[0014] Preferably, the worm and the worm wheel are meshed together.

[0015] Compared with the prior art, the beneficial effects of this utility model are as follows: A solid-phase extraction device with a cleaning structure is described below: The operator rotates the rotating plate inside the fixed base, at which point one side of the rotating plate engages with the top of the support plate. Then, by pulling the sliding rod, the plate slides inside the fixed box, causing the first telescopic spring to contract. Through the restoring property of the first telescopic spring, the movable rod pushes the push plate to move, at which point multiple sets of insert blocks are inserted into the support plate. The operator then replaces and cleans the collection tube after waste liquid collection, thus achieving the effect of quickly adjusting and switching the collection tube, thereby realizing simultaneous solid-phase extraction in the liquid and waste liquid cleaning. The cleaning effect greatly improves the efficiency of solid-phase extraction in liquids and further increases the cleaning speed of the collection tube, avoiding the phenomenon of conflict between the two operations that would affect the efficiency of the device. By rotating the worm gear, the operator drives the worm wheel to rotate, and the rotation of the screw causes the square rod to slide inside the sliding box. At this time, the operator observes the pointer and scale line, thereby achieving precise adjustment of the height of the lifting plate and the extraction column. This allows it to adapt to test tubes of various sizes, enabling the operator to flexibly adjust the position of the extraction column according to actual experimental needs, ensuring that the sample can flow smoothly into the predetermined collection container, thereby improving the flexibility and adaptability of the experiment.

[0016] 1. By having the worker pull the movable plate and slide it inside the top of the base, another set of collection tubes quickly slides into the support frame. Then, the worker rotates the rotating plate inside the fixed seat, at which point one side of the rotating plate engages with the top of the support plate. Pulling the sliding rod and sliding it inside the fixed box causes the first telescopic spring to contract. The movement of the sliding rod drives the movement of the movable rod, which in turn pulls the push plate to slide inside the fixed box. By releasing the sliding rod, the first telescopic spring returns to its original position, allowing the movable rod to push the push plate forward. At this point, multiple sets of insert blocks are inserted into the support plate. The worker then replaces and cleans the collection tubes after waste liquid collection, achieving rapid adjustment and switching of collection tubes. This allows for simultaneous solid-phase extraction in the liquid and waste liquid cleaning, significantly improving efficiency. It achieves high efficiency in solid-phase extraction from liquids and further improves the cleaning speed of the collection tube, avoiding operational conflicts that could affect the efficiency of the device. This provides convenience for operators. The operator slides the support inside the top of the moving plate and then pulls the sliding plate to move the sliding sleeve. At this time, the sliding sleeve slides outside the fixed rod, and the second telescopic spring contracts. By releasing the sliding plate, the tension generated by the second telescopic spring allows multiple sets of insert plates to be inserted into the slots, thereby achieving the effect of quickly adjusting the fixed support. This enables the quick adjustment of the alignment between the collection tube and the extraction column on the support, and effectively reduces the phenomenon of the collection tube and support shifting and falling due to external impacts, greatly improving the stability of the device during use.

[0017] 2. By rotating the worm gear, the operator drives the worm wheel to rotate, which in turn drives the screw. The screw then causes the square rod to slide inside the sliding box. At this time, the operator observes the pointer and scale lines, thus achieving precise adjustment of the lifting plate and the height of the extraction column. This allows for the adaptation to various test tube sizes, enabling the operator to flexibly adjust the position of the extraction column according to actual experimental needs, ensuring that the sample flows smoothly into the predetermined collection container, thereby improving the flexibility and adaptability of the experiment. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0019] Figure 2 This is a partially enlarged structural diagram of the moving mechanism in this utility model;

[0020] Figure 3 This is an enlarged structural diagram of part A in this utility model;

[0021] Figure 4 This is an enlarged structural diagram of part B in this utility model;

[0022] Figure 5This is a schematic diagram of the overall structure of the bracket in this utility model;

[0023] Figure 6 This is a partially enlarged structural diagram of the adjustment component in this utility model.

[0024] In the diagram: 1. Base; 101. Support frame; 102. Lifting plate; 2. Moving mechanism; 201. Moving plate; 202. Support plate; 203. Bracket; 204. Fixed seat; 205. Rotating plate; 206. Fixed box; 207. Slide rod; 208. First telescopic spring; 209. Push plate; 210. Insert block; 211. Movable rod; 212. Fixed frame; 213. Mounting slot; 214. Fixed rod; 215. Sliding sleeve; 216. Second telescopic spring; 217. Slide plate; 218. Insert plate; 219. Slot; 220. Hole / groove; 3. Adjustment assembly; 301. Sliding box; 302. Connecting box; 303. Square rod; 304. Screw; 305. Worm gear; 306. Worm wheel; 307. Pointer; 308. Scale line; 309. Connecting block; 310. Support block; 311. Support rod; 312. Slider. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] Please see Figure 1-6 The present invention provides a technical solution: a solid phase extraction device with a cleaning structure, including a base 1, a support frame 101 is provided at the top of the base 1, and a lifting plate 102 is slidably connected inside the support frame 101; a moving mechanism 2 is provided at the top of the base 1, and an adjustment component 3 is provided on one side of the support frame 101.

[0027] The moving mechanism 2 includes a moving plate 201 slidably connected to the inside of the top of the base 1. Support plates 202 are symmetrically mounted on both sides of the top of the moving plate 201. A bracket 203 is symmetrically slidably connected inside the top of the moving plate 201. A fixed seat 204 is symmetrically mounted on the top of the base 1. A rotating plate 205 is rotatably connected inside the fixed seat 204. One side of the top of the rotating plate 205 is engaged with the support plate 202. A fixed box 206 is mounted on one side of the top of the rotating plate 205. A sliding rod 207 is slidably connected inside the bottom of the fixed box 206. A first telescopic spring 208 is sleeved on the outer side of the bottom of the sliding rod 207. Furthermore, a push plate 209 is slidably connected to one end of the fixed box 206, and a plug block 210 is installed on one side of the push plate 209. The plug block 210 is inserted into the support plate 202. Moreover, a movable rod 211 is rotatably connected to one side of the top of the slide rod 207, and one end of the movable rod 211 is rotatably connected to the push plate 209. This enables the rapid adjustment and switching of the collection tube, thereby achieving the effect of simultaneous solid-phase extraction in liquid and waste liquid cleaning. This greatly improves the efficiency of solid-phase extraction in liquid and further increases the cleaning speed of the collection tube, avoiding the phenomenon of conflict between the two operations that affects the efficiency of the device. This brings convenience to the staff during use.

[0028] A fixed frame 212 is symmetrically installed on the top of the movable plate 201. The fixed frame 212 has symmetrically opened mounting grooves 213 at both ends. A fixed rod 214 is installed inside the mounting groove 213, and a sliding sleeve 215 is slidably connected to the outer side of the fixed rod 214. The sliding sleeve 215 is slidably connected inside the mounting groove 213. A second telescopic spring 216 is sleeved on the outer side of the fixed rod 214. A sliding plate 217 is installed between the sliding sleeves 215, and an insert plate 218 is installed on one side of each sliding plate 217. Slots 219 are symmetrically opened on both sides of the bottom end of the bracket 203, and the insert plate 218 is inserted into the slot 219. The second telescopic spring 216... The tension generated by the spring 216 allows multiple sets of insert plates 218 to be inserted into the slots 219, thereby enabling quick adjustment of the fixed bracket 203. This facilitates quick alignment of the collection tube and extraction column on the bracket 203 and effectively reduces the risk of the collection tube and bracket 203 shifting or falling due to external impacts, greatly improving the stability of the device during use. The top of the bracket 203 has slots 220, allowing operators to insert collection tubes of various specifications into the slots 220 for installation, enhancing its practicality during use.

[0029] The adjusting assembly 3 includes a sliding box 301 fixedly connected to one side of the support frame 101, a connecting box 302 installed at the top of the sliding box 301, a square rod 303 slidably connected inside the sliding box 301, a screw 304 rotatably connected between the sliding box 301 and the connecting box 302, and the square rod 303 threadedly connected to the outer side of the bottom end of the screw 304. A worm gear 305 rotatably connected inside the connecting box 302, and a worm wheel 306 installed on the outer side of the top end of the screw 304, with the worm gear 305 meshing with the worm wheel 306. A pointer 307 is installed on one side of the bottom end of the sliding box 301, and scale lines 308 are provided on one side of the square rod 303. A connecting block 309 is installed at the bottom end of the square rod 303. One end of the lifting plate 102... The lifting plate 102 is fixedly connected to the connecting block 309, thereby enabling precise adjustment of the height of the lifting plate 102 and the extraction column. This allows it to accommodate test tubes of various sizes, enabling staff to flexibly adjust the position of the extraction column according to actual experimental needs, ensuring that the sample flows smoothly into the predetermined collection container, thus improving the flexibility and adaptability of the experiment. Support blocks 310 are symmetrically installed on one side of the support frame 101, and support rods 311 are installed between the support blocks 310. A slider 312 is slidably connected to the outside of the support rod 311, and one end of the lifting plate 102 is fixedly connected to the slider 312. The movement of the lifting plate 102 drives the slider 312 to slide outside the support rod 311, thereby making the movement of the lifting plate 102 more stable.

[0030] Working principle: Before using this solid-phase extraction device with a cleaning structure, it is necessary to check the overall condition of the device to ensure it can operate normally. Figure 1 - Figure 6As shown, firstly, the operator operates the valve to flush the extraction column with the flushing liquid. The waste liquid generated during flushing flows into the collection tube. Then, the operator pulls the movable plate 201 to slide it inside the top of the base 1, causing another set of collection tubes to quickly slide into the support frame 101. Next, the operator rotates the rotating plate 205 inside the fixed seat 204, at which point one side of the rotating plate 205 engages with the top of the support plate 202. Then, by pulling the sliding rod 207 inside the fixed box 206, the first telescopic spring 208 contracts, and the sliding rod 207... The movement of the movable rod 211 causes the movable rod 211 to move, which in turn pulls the push plate 209 to slide inside the fixed box 206. By releasing the slide rod 207, and then through the reset property of the first telescopic spring 208, the movable rod 211 pushes the push plate 209 to move. At this time, multiple sets of insert blocks 210 are inserted into the support plate 202. At this time, the staff can replace and clean the collection tube after the waste liquid is collected, thereby achieving the effect of quickly adjusting and switching the collection tube. This enables the simultaneous solid-phase extraction in the liquid and waste liquid cleaning, greatly improving the efficiency. The efficiency of solid-phase extraction in liquid is improved, and the cleaning speed of the collection tube can be further improved. This avoids the phenomenon of conflict between the two operations affecting the efficiency of the device, and brings convenience to the staff. The staff slides the bracket 203 inside the top of the moving plate 201, and then pulls the slide plate 217 to drive the sliding sleeve 215 to move. At this time, the sliding sleeve 215 slides outside the fixed rod 214. At this time, the second telescopic spring 216 contracts. By releasing the slide plate 217, the tension generated by the second telescopic spring 216 allows multiple sets of insert plates 218 to be inserted into the slots 219, thereby achieving the effect of quickly adjusting the fixed bracket 203. This allows for quick adjustment of the alignment of the collection tube and the extraction column on the bracket 203, and effectively reduces the phenomenon of the collection tube and bracket 203 shifting and falling due to external impact on the device, greatly improving the stability of the device during use. Through the slot 220 opened at the top of the bracket 203, the staff can insert various specifications of collection tubes into the slot 220 for installation, bringing practicality to the staff during use.

[0031] By rotating the worm gear 305, the operator drives the worm wheel 306 to rotate, which in turn drives the screw 304 to rotate. The screw 304 then causes the square rod 303 to slide inside the sliding box 301. At this time, the operator observes the pointer 307 and the scale line 308, thus achieving precise adjustment of the height of the lifting plate 102 and the extraction column. This allows for the adaptation to various test tube sizes, enabling the operator to flexibly adjust the position of the extraction column according to actual experimental needs, ensuring that the sample flows smoothly into the predetermined collection container, thereby improving the flexibility and adaptability of the experiment. The movement of the lifting plate 102 causes the slider 312 to slide outside the support rod 311, making the movement of the lifting plate 102 more stable.

[0032] In the prior art, CN220360742U discloses a solid phase extraction device using a support frame 101 and a lifting plate 102. The device used in this device will not be described in detail here.

[0033] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A solid phase extraction device with a cleaning structure, comprising a base (1), wherein a support frame (101) is provided at the top of the base (1), and a lifting plate (102) is slidably connected inside the support frame (101); Its features are, Also includes: The base (1) is provided with a moving mechanism (2) at its top, and an adjusting component (3) is provided on one side of the support frame (101); The moving mechanism (2) includes a moving plate (201) slidably connected to the inside of the top of the base (1), and support plates (202) are symmetrically installed on both sides of the top of the moving plate (201). A bracket (203) is symmetrically slidably connected inside the top of the moving plate (201). A fixed seat (204) is symmetrically installed on the top of the base (1). A rotating plate (205) is rotatably connected inside the fixed seat (204). One side of the top of the rotating plate (205) is fastened to the support plate (202). A fixed bracket is installed on one side of the top of the rotating plate (205). The fixed box (206) has a sliding rod (207) slidably connected inside the bottom end of the fixed box (206), and a first telescopic spring (208) is sleeved on the outer side of the bottom end of the sliding rod (207). A push plate (209) is slidably connected inside one end of the fixed box (206), and a plug (210) is installed on one side of the push plate (209). The plug (210) is inserted into the support plate (202). A movable rod (211) is rotatably connected to one side of the top end of the sliding rod (207), and one end of the movable rod (211) is rotatably connected to the push plate (209).

2. The solid-phase extraction apparatus with a cleaning structure according to claim 1, characterized in that: The top of each movable plate (201) is symmetrically equipped with a fixed frame (212), and the two ends of the fixed frame (212) are symmetrically provided with mounting grooves (213). The mounting grooves (213) are equipped with fixed rods (214), and the outer side of the fixed rods (214) is slidably connected with a sliding sleeve (215). The outer side of the fixed rods (214) is sleeved with a second telescopic spring (216). The sliding sleeves (215) are installed with a sliding plate (217). The sliding plate (217) is equipped with a plug plate (218) on one side. The bottom end of the bracket (203) is symmetrically provided with slots (219), and the plug plates (218) are inserted into the slots (219).

3. A solid-phase extraction apparatus with a cleaning structure according to claim 1, characterized in that: The adjustment assembly (3) includes a sliding box (301) fixedly connected to one side of the support frame (101), and a connecting box (302) is installed at the top of the sliding box (301). A square rod (303) is slidably connected inside the sliding box (301). A screw (304) is rotatably connected between the sliding box (301) and the connecting box (302). The square rod (303) is threadedly connected to the outside of the bottom end of the screw (304). A worm gear (305) is rotatably connected inside the connecting box (302). A worm wheel (306) is installed on the outside of the top end of the screw (304). A pointer (307) is installed on one side of the bottom end of the sliding box (301). A scale line (308) is opened on one side of the square rod (303). A connecting block (309) is installed at the bottom end of the square rod (303). One end of the lifting plate (102) is fixedly connected to the connecting block (309).

4. A solid-phase extraction apparatus with a cleaning structure according to claim 3, characterized in that: Support blocks (310) are symmetrically installed on one side of the support frame (101), and support rods (311) are installed between the support blocks (310). A slider (312) is slidably connected to the outside of the support rod (311), and one end of the lifting plate (102) is fixedly connected to the slider (312).

5. A solid-phase extraction apparatus with a cleaning structure according to claim 1, characterized in that: The top of each bracket (203) is provided with a slot (220).

6. A solid-phase extraction apparatus with a cleaning structure according to claim 2, characterized in that: The sliding sleeve (215) is slidably connected inside the mounting groove (213).

7. A solid-phase extraction apparatus with a cleaning structure according to claim 3, characterized in that: The worm (305) is meshed with the worm wheel (306).

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