Collision reaction tank based on printed circuit board

Abstract

The utility model provides a printed circuit board-based collision reaction tank, which comprises a main tank body, an inlet electrode, an outlet electrode, a front base, a rear base and a printed circuit board, the printed circuit board is fixedly connected with the main tank body through a structural member, the front base and the rear base are arranged on the main tank body through a sealing ring, and the inlet electrode and the outlet electrode are arranged on the main tank body. The front base and the rear base are used for installing an inlet electrode and an outlet electrode, copper is laid on the surface of the printed circuit board in a segmented mode, and gradient direct-current voltage bias is applied to the surface of the printed circuit board so that the axial electric field function can be achieved. According to the utility model, not only can good ion transmission efficiency be ensured, but also quality screening to a certain degree can be realized.

Description

TECHNICAL FIELD

[0001] The utility model relates to mass spectrometer technical field, concretely relates to a collision reaction cell based on printed circuit board. BACKGROUND

[0002] In the analysis process of inductively coupled plasma quadrupole mass spectrometer (ICP-QMS), it is easy to be interfered by polyatomic ions, isotope ions and double-charge ions. The introduction of collision reaction cell technology obviously improves the detection limit and chemical resolution of inductively coupled plasma quadrupole mass spectrometer, and expands its application in the fields of trace / ultra-trace multi-element analysis, isotope ratio analysis and morphological analysis.

[0003] In some types of tandem mass spectrometry, after obtaining a strong quasi-molecular ion peak of the measured substance under the condition of primary mass spectrometry (MS), the quasi-molecular ion needs to be collisionally fragmented, and more abundant compound fragment information is obtained by tandem mass spectrometry (MS / MS) to judge the structure of the compound and realize quantitative analysis of the target compound. Therefore, the collision reaction cell is also the core ion optical component of tandem mass spectrometry.

[0004] At present, the main structure of the collision reaction cell for ion transmission generally adopts a multipole rod form, including quadrupole rods, hexapole rods and octapole rods, and an axial electric field is established by tilting the poles or increasing special-shaped rods to ensure the axial ion kinetic energy, so that the ions of interest can smoothly pass through the collision reaction cell. This structure form has high assembly difficulty and high research and development and manufacturing cost. UTILITY MODEL CONTENT

[0005] Therefore, the utility model wants to solve the problem to provide a collision reaction cell based on a printed circuit board.

[0006] To solve the above technical problems, the utility model adopts the technical scheme of a collision reaction cell based on a printed circuit board, which comprises a main cell body, an inlet electrode, an outlet electrode, a front base, a rear base and a printed circuit board, the printed circuit board is fixedly connected with the main cell body through a structural member, the front base and the rear base are installed with the main cell body through a sealing ring, the front base and the rear base are used for installing the inlet electrode and the outlet electrode, and the surface of the printed circuit board is segmentedly laid with copper and gradient direct current voltage bias is applied to realize the axial electric field function.

[0007] In the utility model, preferably, the inlet electrode and the outlet electrode are provided as stainless steel circular sheets or rectangular sheets with through holes.

[0008] In the utility model, preferably, the aperture size of the through hole is set to 1mm-3mm, and the hole thickness is set to 0.3mm-0.6mm.

[0009] In the utility model, preferably, the material of the front base and the rear base adopts ceramic, polycarbonate or polyether ether ketone.

[0010] In the utility model, preferably, the main pool body is provided as a cylindrical or cuboid hollow structure, and the material of the main pool body is alumina ceramic, aluminum alloy or stainless steel.

[0011] In the utility model, preferably, the sealing ring is provided as a rubber ring or a tetrafluoroethylene ring.

[0012] In the utility model, preferably, the material of the structural member adopts polyether ether ketone or polyimide.

[0013] In the utility model, preferably, the main pool body is provided with a gas path connecting hole, the gas path connecting hole is used for passing in collision gas or reaction gas, and the collision gas or reaction gas adopts one or more of helium, methane, ammonia, nitrogen, oxygen or argon.

[0014] In the utility model, preferably, the front and rear sides of the printed circuit board are provided with electronic connecting pieces for power feeding, the electronic connecting pieces adopt spring contact pin structures or screw structures, the electronic connecting pieces are provided with direct current voltage bias of certain frequency variation and are used for binding ions in the main pool body to reciprocate in the main pool body.

[0015] The utility model has the advantages and positive effects that: the inlet electrode, the outlet electrode, the front base, the rear base and the main pool body jointly form a semi-closed pool body, the ion transmission assembly, the mechanical connecting structure and the electronic connecting piece formed by arranging the printed circuit boards according to certain directions, four groups of printed circuit boards form a quadrupole electric field coupled with high-order multipole field, good ion transmission efficiency can be ensured, and a certain degree of mass selection can be realized. BRIEF DESCRIPTION OF DRAWINGS

[0016] The drawings are used to provide further understanding of the utility model and constitute a part of the specification, are used to explain the utility model together with the embodiments of the utility model and do not constitute the limitation to the utility model.

[0017] Figure 1 It is the overall structure diagram of the collision reaction pool based on the printed circuit board of the utility model;

[0018] Figure 2 It is the circuit connection schematic view of the collision reaction pool based on the printed circuit board of the utility model;

[0019] Figure 3aIt is a first copper-paved potential distribution schematic diagram of a collision reaction pool based on a printed circuit board.

[0020] Figure 3b It is a second copper-paved potential distribution schematic diagram of a collision reaction pool based on a printed circuit board.

[0021] In the figure: 1, inlet electrode; 2, outlet electrode; 3, front base; 4, rear base; 5, main pool body; 6, structural member; 7, printed circuit board; 8, sealing ring; 9, connecting piece; 10, connecting hole. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative work fall within the scope of the present application.

[0023] It should be noted that when a component is referred to as being "fixed" to another component, it can be directly on the other component or there can be intervening components. When a component is referred to as being "connected" to another component, it can be directly connected to the other component or there can be intervening components. When a component is referred to as being "disposed" on another component, it can be directly on the other component or there can be intervening components. The terms "vertical", "horizontal", "left", "right", and similar terms as used herein are for purposes of illustration and description only and not for limiting the present application.

[0024] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description of the application herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in this description, the terms "therefore" and "because" are merely used to introduce an explanation of associated elements. The term "and / or" includes any and all combinations of one or more of the associated listed items.

[0025] As Figure 1As shown, the utility model provides a kind of collision reaction pool based on printed circuit board 7, including main pool body 5, inlet electrode 1, outlet electrode 2, front pedestal 3, rear pedestal 4 and printed circuit board 7, the printed circuit board 7 is fixedly connected with the main pool body 5 by structural member 6, the front pedestal 3 and the rear pedestal 4 are installed with the main pool body 5 by sealing ring 8, the front pedestal 3 and rear pedestal 4 are used to install inlet electrode 1 and outlet electrode 2, the surface of printed circuit board 7 is segmented copper and applies gradient direct current voltage bias to realize axial electric field function.Coupled with the rear pedestal 4 and the main pool body 5, inlet electrode 1, outlet electrode 2, front pedestal 3 form semi-closed pool body, in the embodiment, printed circuit board 7 is provided as four groups, and the ion transmission assembly, mechanical connection structure and electronic connecting piece 9 that four groups of printed circuit board 7 are arranged according to certain direction are formed, and four groups of printed circuit board 7 constitute quadrupole electric field coupled with high-order multipole field, which can not only ensure good ion transmission efficiency, but also realize a certain degree of mass screening.Copper is segmented on the surface of printed circuit board 7, and gradient direct current voltage bias is applied, so that axial electric field function can be realized.

[0026] Printed circuit board 7 is used as effective electrode. The circuit board is rectangular, and the four groups of circuit boards are uniformly arranged in up, down, left and right. The spacing between the relative circuit boards depends on the preset mass range, alternating voltage operating frequency, voltage amplitude and other parameters according to the quadrupole electric field and quadrupole rod ion transmission principle. The inner side of the printed circuit board 7 electrode is coppered according to a certain rule, and after the alternating voltage is applied, an alternating electric field can be formed around the four groups of circuit boards, which is similar to a quadrupole electric field and couples high-order multipole field components. By using multi-section coppering, a direct current voltage bias with a certain gradient is applied, which can form a potential gradient in the axial direction of the circuit board around the region, i.e. an axial electric field. The outer side of the circuit board, i.e. the back of the coppered side, is composed of a group of DC / AC distribution circuits, which realize the coupling and gradient application of alternating voltage and direct current voltage respectively, as shown in Figure 2 .

[0027] The coppering width and spacing of the printed circuit board 7 can be adjusted according to the actual required potential gradient. Figure 3a and 3b show two different coppering width settings, and the corresponding potential curves on the axial line. Similarly, the resistance value of the voltage dividing resistor on the back of the circuit board can also be adjusted to obtain a special potential distribution curve.

[0028] The combination form of the printed circuit board 7 is not limited to the uniform arrangement of four groups, and can be a combination form of six groups, eight groups, twelve groups, etc. It can be quickly designed and experimented according to the potential well width requirement and experimental purpose. The front and rear of the printed circuit board 7 electrode can be installed with multipole rod assemblies, such as quadrupole rods, sextupole rods, octupole rods, etc., for ion guiding and focusing transmission, reducing the influence of edge electric field, and improving the matching degree of front and rear ion optical assemblies.

[0029] The mounting form of the printed circuit board 7 is not limited to the mounting structure described in this patent, and can also be a front and rear side assembly of a polyether ether ketone structure 6, a circuit board provided with a groove for insertion assembly, etc.

[0030] In this embodiment, further, the inlet electrode 1 and the outlet electrode 2 are provided as a stainless steel circular sheet or a rectangular sheet with a through hole, and the diameter of the circular hole is adjusted according to the collision pool gas pressure and the vacuum environment.

[0031] In this embodiment, further, the aperture size of the through hole is set to 1-3 mm, and the hole thickness is set to 0.3-0.6 mm.

[0032] In this embodiment, further, the front base 3 and the rear base 4 are made of ceramic, polycarbonate or polyether ether ketone, and are used for mounting the inlet electrode 1 and the outlet electrode 2, and mounting and positioning of the collision reaction pool assembly in the mass spectrometry ion optical system.

[0033] In this embodiment, further, the main pool body 5 is provided as a cylindrical or cuboid hollow structure, and the material of the main pool body 5 is alumina ceramic, aluminum alloy or stainless steel.

[0034] In this embodiment, further, the sealing ring 8 is provided as a rubber ring or a tetrafluoroethylene ring.

[0035] In this embodiment, further, the structure 6 is made of polyether ether ketone or polyimide.

[0036] In this embodiment, further, the main pool body 5 is provided with a gas path connecting hole 10, which is used to introduce collision gas or reaction gas, and the collision gas or reaction gas is one or more of helium, methane, ammonia, nitrogen, oxygen or argon.

[0037] In this embodiment, further, the front and rear sides of the printed circuit board 7 are provided with electronic connectors 9 for power supply, which are provided with spring needle structures or screw structures, and are provided with direct current voltage bias with certain frequency variation, for binding the ions in the main pool body 5 to reciprocate inside the main pool body 5.

[0038] The front and rear sides of the printed circuit board 7 are provided with electronic connectors 9 for power supply, which are provided with spring needle structures or screw structures, and are provided with direct current voltage bias with certain frequency variation, for binding the ions in the main pool body 5 to reciprocate inside the main pool body 5.

[0039] The functions that can be achieved by this collision reaction pool include but are not limited to:

[0040] 1. Without gas, only AC and DC bias is applied, used as ion guiding transmission device;

[0041] 2. Helium, hydrogen or nitrogen is introduced, and small ion initial kinetic energy is set to realize ion beam cooling focusing;

[0042] 3. Helium or hydrogen is introduced, and a voltage threshold, i.e. ion passing kinetic energy threshold, is set for outlet electrode 2, after ion molecular collision, only the ion with kinetic energy exceeding the threshold can pass through the collision cell, and multi-atomic ion removal effect is realized;

[0043] 4. Hydrogen, oxygen, methane, ammonia and other gases are introduced, small ion initial kinetic energy and reasonable axial electric field are set, interference ions or measured ions are reacted with active gas molecules, and interference ion removal is realized;

[0044] 5. Nitrogen, argon and other gases are introduced, and large ion initial kinetic energy is set to realize ion collision dissociation and obtain ion fragment information.

[0045] The embodiments of the utility model are described in detail above, but the content described can only be the preferred embodiment of the utility model, and cannot be considered as limiting the scope of the utility model. Any equivalent change and improvement within the scope of the utility model should still belong to the scope covered by the patent.

Claims

1. A printed circuit board based collision reaction cell characterized by, The collision reaction cell comprises a main cell body, an inlet electrode, an outlet electrode, a front base, a rear base and a printed circuit board, the printed circuit board is fixedly connected with the main cell body through a structural member, the front base and the rear base are mounted with the main cell body through a sealing ring, the front base and the rear base are used for mounting the inlet electrode and the outlet electrode, and the surface of the printed circuit board is segmentedly laid with copper and gradient direct current voltage bias is applied to realize the axial electric field function.

2. A printed circuit board-based collisional reaction cell according to claim 1, wherein, The inlet electrode and the outlet electrode are provided as a stainless steel circular sheet or a rectangular sheet with a through hole.

3. A printed circuit board-based collisional reaction cell according to claim 2, wherein, The aperture size of the through hole is 1mm-3mm, and the hole thickness is 0.3mm-0.6mm.

4. A printed circuit board-based collisional reaction cell according to claim 1, wherein, The material of the front base and the rear base is ceramic, polycarbonate or polyether ether ketone.

5. A printed circuit board-based collisional reaction cell according to claim 1, wherein, The main cell body is provided as a cylindrical or cuboid hollow structure, and the material of the main cell body is alumina ceramic, aluminum alloy or stainless steel.

6. A printed circuit board-based collisional reaction cell according to claim 1, wherein, The sealing ring is provided as a rubber ring or a tetrafluoroethylene ring.

7. A printed circuit board-based collisional reaction cell according to claim 1, wherein, The material of the structural member is polyether ether ketone or polyimide.

8. A printed circuit board-based collisional reaction cell according to claim 1, wherein, The main cell body is provided with a gas connection hole, the gas connection hole is used for introducing collision gas or reaction gas, and the collision gas or reaction gas is one or more of helium, methane, ammonia, nitrogen, oxygen or argon.

9. A printed circuit board-based collisional reaction cell according to claim 1, wherein, The front and rear sides of the printed circuit board are both provided with electronic connectors for power feeding, the electronic connectors are provided in a spring needle structure or a screw structure, the electronic connectors are provided with direct current voltage bias with a certain frequency change, and are used for binding the ions in the main cell body to reciprocate in the main cell body.

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