Polypeptide synthesis stirring device capable of fully stirring
By combining a preheating structure with a nitrogen pump and enhancing the design of the stirring blades and scrapers, the problem of low efficiency in existing peptide synthesis devices has been solved, enabling rapid mixing and heating and improving processing efficiency.
Patent Information
- Application Number
- CN202423095408.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-16
- Publication Date
- 2025-12-23
- Estimated Expiration
- 2034-12-16
AI Technical Summary
Existing peptide synthesis stirring devices are inefficient during use, requiring long periods of stirring and mixing, resulting in slow processing efficiency.
The raw materials are heated by a preheating structure, and nitrogen is delivered while stirring by connecting a nitrogen pump and a rotary joint. The mixing efficiency is improved by the design of the stirring blades and scrapers. At the same time, the heating wire is connected by a conductive slip ring to increase the mixing range by stirring and heating simultaneously.
It effectively saves processing time and improves the mixing and processing efficiency of peptide synthesis.
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Figure CN223697445U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to polypeptide production technical field especially relates to a polypeptide synthesis stirring device of full -blown stirring. BACKGROUND
[0002] Peptide is alpha amino acid and is linked together with peptide bond and is formed compound, is protein hydrolysis's intermediate product, and the compound that two amino acid molecules are dehydrated condensation is called dipeptide, and the same reason extrapolates also tripeptide, tetrapeptide and pentapeptide, the peptide that three or three or more amino acid molecules are composed is called polypeptide, needs to use stirring device to mix polypeptide in polypeptide production process.
[0003] There are still some problems in the use process of the existing polypeptide synthesis stirring device, and the polypeptide needs to be stirred for a long time in the use process, and the efficiency is slow, therefore, the technical personnel in the art provides a polypeptide synthesis stirring device of full -blown stirring to solve the problems in the above background technology. UTILITY MODEL CONTENT
[0004] The utility model discloses a polypeptide synthesis stirring device of full -blown stirring that an utility model relates to polypeptide production technical field especially relates to a polypeptide synthesis stirring device of full -blown stirring, through preheating structure to the raw material of next batch carries out heating, when stirring mixes, it is convenient to save processing time to improve the efficiency of processing, and then through the connection between nitrogen gas pump and swivel joint, it is convenient to improve the efficiency of mixing to carry out stirring and convey nitrogen gas.
[0005] In order to achieve the above object, the utility model provides the following technical scheme: a polypeptide synthesis stirring device of full -blown stirring, including stirring box and control box, the control box is arranged at one side of stirring box, the upper end face center of stirring box is rotatably connected with the flap, the lower end face center of stirring box is fixedly connected with the discharge valve, the input end of discharge valve penetrates the lower end face of stirring box and reaches the lower inner wall of stirring box, the upper end face center of stirring box is fixedly connected with stirring mixing structure, stirring mixing structure includes servo motor, the output end of servo motor is fixedly connected with swivel joint, the upper end face of stirring box is connected with the upper inner wall of stirring box through swivel joint, the fixed end of swivel joint is fixedly connected between stirring box, the upper end face of one side stirring box of servo motor is equipped with nitrogen gas pump, the output end of nitrogen gas pump penetrates the upper end face of stirring box, and the input end of swivel joint is connected between end and swivel joint, the output end of servo motor is fixedly connected with the rotary end of swivel joint, the rotary end of swivel joint is fixedly connected with stirring shaft, the upper end face center of stirring box is fixedly connected with preheating structure behind,
[0006] Through the technical scheme, the next batch of raw materials is heated by the preheating structure, and when stirring and mixing, the processing time is saved, thereby improving the processing efficiency, and nitrogen gas is conveyed while stirring through the connection between the nitrogen gas pump and the rotary joint, thereby improving the mixing efficiency.
[0007] Further, a gas passage is arranged at the center of the stirring shaft, and the gas passage is connected with the output end of the rotary joint; a connecting rod is fixedly connected to the upper center of the two side walls of the stirring shaft; a communication passage is arranged in each of the two connecting rods; a stirring blade is fixedly connected to the other end of each of the two connecting rods; a plurality of one-way valves are arranged on the upper end surface of each of the two stirring blades; the input ends of the plurality of one-way valves are connected with the two communication passages, respectively; and a scraper is fixedly connected to the other end of each of the two stirring blades, and the other end of each of the two scrapers is fixedly connected to the two side walls of the stirring shaft.
[0008] Through the technical scheme, nitrogen gas is conveyed into the gas passage through the rotary joint connected with the nitrogen gas pump, and then conveyed into the plurality of one-way valves through the two communication passages, so that the raw materials in the stirring box are stirred and conveyed with nitrogen gas, thereby improving the mixing efficiency; and the two stirring blades and the two scrapers are arranged to make the mixing and turning range of the raw materials larger, thereby improving the mixing efficiency.
[0009] Further, a conductive slip ring is fixedly connected to the lower end of the stirring shaft, and the conductive slip ring is fixedly connected to the center of the lower inner wall of the stirring box; a connecting wire is arranged at each of the front and rear ends of the stirring shaft; a plurality of stirring rods are arranged in the center of the front and rear end surfaces of the stirring shaft in an up-down arrangement; a heating wire is arranged in each of the plurality of stirring rods; and the plurality of heating wires are fixedly connected with the two connecting wires, respectively.
[0010] Through the technical scheme, the rotating end of the conductive slip ring is connected with the two connecting wires, so that the plurality of heating wires can be electrified and heated while stirring, thereby improving the mixing efficiency.
[0011] Furthermore, the preheating structure includes a storage tank, the storage tank having a heat-conducting layer inside, and an air exchange pump fixedly connected to the upper inner wall of the mixing tank at the lower end of the storage tank. The output end of the air exchange pump passes through the upper inner wall of the mixing tank, the lower inner wall of the storage tank, and one inner side wall of the storage tank sequentially to one side of the storage tank, and is fixedly connected to a connecting pipe at its end. The output end of the connecting pipe passes through the upper center of the rear end face of the storage tank to the interior of the storage tank, and is fixedly connected to a heat-conducting pipe at its end. The heat-conducting pipe is wound around the outside of the heat-conducting layer, and is fixedly connected to an air outlet at its end. The output end of the air outlet passes through the lower inner wall of the storage tank and the upper end face of the mixing tank sequentially to the upper inner wall of the mixing tank. A discharge valve is fixedly connected to the upper inner wall of the mixing tank at the lower end of the storage tank, and the input end of the discharge valve passes through the upper inner wall of the mixing tank and the lower end face of the storage tank sequentially to the lower inner wall of the storage tank.
[0012] With the above technical solution, during use, by controlling the start of the air exchange pump, the air exchange pump delivers hot air from inside the mixing tank to the inside of the connecting pipe, and then transfers the heat to the heat-conducting layer through the heat-conducting pipe, thereby heating the raw material inside the heat-conducting layer. After preheating, the preheated raw material is delivered to the mixing tank through the discharge valve, thereby improving the processing efficiency.
[0013] Furthermore, a feed valve is fixedly connected to the center of the upper end face of the storage box;
[0014] The above technical solution facilitates the addition of raw materials into the storage tank via the feed valve.
[0015] This utility model has the following beneficial effects:
[0016] In this invention, a polypeptide synthesis stirring device capable of thorough stirring is connected to a rotary joint via a nitrogen pump. Nitrogen is then supplied into the gas channel via the rotary joint and then to multiple one-way valves via two connecting channels. These one-way valves simultaneously supply nitrogen to the raw materials inside the mixing chamber, thereby improving mixing efficiency. Furthermore, the arrangement of two stirring blades and two scrapers allows for greater agitation of the raw materials, further enhancing mixing efficiency.
[0017] In this invention, the rotating end of a conductive slip ring is connected to two connecting wires, which facilitates the heating of multiple heating wires while stirring, thereby improving the mixing efficiency.
[0018] In this invention, during use, the air exchange pump is started and transports hot air from inside the mixing tank to the connecting pipe. The heat is then transferred to the heat-conducting layer through the heat-conducting pipe, thereby heating the raw material inside the heat-conducting layer. After preheating, the preheated raw material is transported back into the mixing tank through the discharge valve, thus improving processing efficiency. Attached Figure Description
[0019] Figure 1 A perspective view of the polypeptide synthesis stirring device with sufficient stirring is provided for the utility model;
[0020] Figure 2 A perspective view of the polypeptide synthesis stirring device with sufficient stirring is provided for the utility model;
[0021] Figure 3 A perspective view of the polypeptide synthesis stirring device with sufficient stirring is provided for the utility model;
[0022] Figure 4 A perspective view of the polypeptide synthesis stirring device with sufficient stirring is provided for the utility model.
[0023] Legend:
[0024] 1, stirring box; 2, control box; 3, preheating structure; 301, storage box; 302, heat conduction layer; 303, feeding valve; 304, air exchange pump; 305, connecting pipe; 306, heat conduction pipe; 307, air outlet; 308, discharge valve; 4, stirring and mixing structure; 401, servo motor; 402, nitrogen pump; 403, rotary joint; 404, stirring shaft; 405, air duct; 406, conductive slip ring; 407, connecting rod; 408, stirring blade; 409, communication channel; 410, one-way valve; 411, scraper; 412, connecting line; 413, stirring rod; 414, heating wire; 5, flip cover; 6, discharge valve. DETAILED DESCRIPTION
[0025] The technical solutions in the embodiments of the utility model will be described clearly and completely below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all the other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.
[0026] Reference Figures 1-4The utility model provides a kind of polypeptide synthesis stirring device of sufficient stirring, including stirring box 1 and control box 2, control box 2 is arranged at the side of stirring box 1, the upper end face center of stirring box 1 is rotatably connected with lid 5, the lower end face center of stirring box 1 is fixedly connected with discharge valve 6, the input end of discharge valve 6 is through the lower end face of stirring box 1 and reaches the lower inner wall of stirring box 1, the upper end face center of stirring box 1 is fixedly connected with stirring mixing structure 4, and stirring mixing structure 4 includes servo motor 401, and servo motor 401 output end is fixedly connected with swivel joint 403, and swivel joint 403 is through the upper end face of stirring box 1 and reaches the upper inner wall of stirring box 1, and the fixed end of swivel joint 403 is fixedly connected between stirring box 1, and the upper end face of stirring box 1 of one side of servo motor 401 is equipped with nitrogen gas pump 402, and nitrogen gas pump 402 output end is through the upper end face of stirring box 1, and end portion is connected between the input end of swivel joint 403, and the output end of servo motor 401 is fixedly connected between the rotary end of swivel joint 403, and the rotary end of swivel joint 403 is fixedly connected with stirring shaft 404, and the upper end face center of stirring box 1 is fixedly connected with preheating structure 3 behind, heats next batch of raw materials by preheating structure 3, when stirring mixing, it is convenient to save processing time, to improve the efficiency of processing, and then be connected between nitrogen gas pump 402 and swivel joint 403, and nitrogen gas is transported while stirring, to improve the efficiency of mixing.
[0027] Gas passage 405 is connected between the output end of swivel joint 403, and the center of stirring shaft 404 is fixedly connected with connecting rod 407, and the center of the two side walls of stirring shaft 404 is fixedly connected with connecting rod 407, and the inside of two connecting rods 407 is all set with communication channel 409, and the other end of two connecting rods 407 is all fixedly connected with stirring blade 408, and the upper end face of two stirring blades 408 is all equipped with multiple check valves 410, and the input end of multiple check valves 410 is connected between two communication channels 409, and the other end of two stirring blades 408 is all fixedly connected with scraper 411, and the other end of two scrapers 411 is respectively fixedly connected on the two side walls of two stirring shafts 404, nitrogen gas is transported to multiple check valves 410 by nitrogen gas pump 402 connecting swivel joint 403, rotating joint 403, and then be transported to multiple check valves 410 by two communication channels 409, and nitrogen gas is transported while stirring to the raw materials in stirring box 1 by multiple check valves 410, to improve the efficiency of mixing, and the setting of two stirring blades 408 and two scrapers 411 makes the amplitude of raw material mixing and turning greater, to improve the efficiency of mixing.
[0028] The lower end of the stirring shaft 404 is fixedly connected with a conductive slip ring 406, the conductive slip ring 406 is fixedly connected at the center of the lower inner wall of the stirring box 1, the inside of the stirring shaft 404 is provided with a connecting wire 412 at the front and rear ends, the center of the front and rear end faces of the stirring shaft 404 is provided with a plurality of stirring rods 413 arranged in up and down directions, the inside of each of the plurality of stirring rods 413 is provided with a heating wire 414, the plurality of heating wires 414 are fixedly connected between the two connecting wires 412 respectively, the rotating end of the conductive slip ring 406 is connected between the two connecting wires 412, so as to facilitate the power heating of the plurality of heating wires 414, and the stirring and heating are carried out at the same time, thereby improving the mixing efficiency.
[0029] The preheating structure 3 comprises a storage box 301, the inside of the storage box 301 is provided with a heat conduction layer 302, the upper inner wall of the stirring box 1 at the lower end of the storage box 301 is fixedly connected with an air exchange pump 304, the output end of the air exchange pump 304 penetrates the upper inner wall of the stirring box 1, the lower inner wall of the storage box 301 and one of the inner side walls of the storage box 301 in sequence and reaches one side of the storage box 301, and the end is fixedly connected with a connecting pipe 305, the output end of the connecting pipe 305 penetrates the upper part of the center of the rear end face of the storage box 301 and reaches the inside of the storage box 301, and the end is fixedly connected with a heat conduction pipe 306, the heat conduction pipe 306 is wound outside the heat conduction layer 302, the end of the heat conduction pipe 306 is fixedly connected with an air outlet 307, the output end of the air outlet 307 penetrates the upper end face of the stirring box 1 and the lower inner wall of the storage box 301 in sequence and reaches the upper inner wall of the stirring box 1, the upper inner wall of the stirring box 1 at the lower end of the storage box 301 is fixedly connected with a discharge valve 308, the input end of the discharge valve 308 penetrates the upper inner wall of the stirring box 1 and the lower end face of the storage box 301 in sequence and reaches the lower inner wall of the storage box 301, during use, the air exchange pump 304 is started by control, the air exchange pump 304 delivers the hot air in the stirring box 1 to the inside of the connecting pipe 305, and then the heat is transferred to the heat conduction layer 302 through the heat conduction pipe 306, so as to heat the raw materials on the inside of the heat conduction layer 302, and then the preheated raw materials are delivered to the inside of the stirring box 1 through the discharge valve 308, thereby improving the processing efficiency.
[0030] The center of the upper end face of the storage box 301 is fixedly connected with a feeding valve 303, so as to add raw materials to the inside of the storage box 301 through the feeding valve 303.
[0031] Working principle: in use, by opening the flip 5, to the inside of the stirring box 1 adds the raw material required for polypeptide synthesis, then through the control servo motor 401 start, servo motor 401 drives the rotary joint 403 rotation end rotation, thereby driving the stirring shaft 404 rotation, through nitrogen pump 402 connecting rotary joint 403, through the rotary joint 403 to the inside of the airway 405 nitrogen gas delivery, again through two communication channel 409 to a plurality of one-way valve 410, through a plurality of one-way valve 410 to the inside of the raw material stirring box 1 nitrogen gas transmission, thereby improving the efficiency of mixing, and through the two stirring blade 408 and two scraper 411 setting, the range of raw material mixing turnover is larger, facilitate to improve the efficiency of mixing, through the rotating end of the conductive slip ring 406 and two connecting line 412 between the connection, thereby facilitating the power supply to a plurality of heating wire 414 heating, stirring while heating, thereby improving the efficiency of mixing.
[0032] During use, by controlling the air exchange pump 304 start, the air exchange pump 304 will be inside the stirring box 1 hot air delivery to the connecting pipe 305, then through the heat pipe 306 heat transfer to the heat conduction layer 302, thereby heating the inside of the raw material of heat conduction layer 302, preheating again through the discharge valve 308 after preheating the raw material is delivered to the inside of the stirring box 1, thereby improving the efficiency of processing, after mixing, by controlling the discharge valve 6 open, the mixed polypeptide is discharged through the discharge valve 6.
[0033] Finally, it should be noted that: the above only for the preferred embodiments of the present application have, and not for limiting the present application, although the foregoing detailed description of the present application is made with reference to the foregoing embodiments, for the person skilled in the art, it still can be modified, or part of the technical features of the equivalent replacement, within the spirit and principles of the present application, any modification, equivalent replacement, improvement, etc., should be included in the scope of protection of the present application.
Claims
1. A fully stirrable polypeptide synthesis stirring device comprising a stirring box (1) and a control box (2) provided at one side of the stirring box (1), characterized in that: The upper end face of the stirring box (1) is rotationally connected with a flip cover (5) at the front center, the lower end face of the stirring box (1) is fixedly connected with a discharge valve (6) at one side, the input end of the discharge valve (6) penetrates through the lower end face of the stirring box (1) and reaches the lower inner wall of the stirring box (1), the upper end face of the stirring box (1) is fixedly connected with a stirring and mixing structure (4) at the center, the stirring and mixing structure (4) comprises a servo motor (401), the output end of the servo motor (401) is fixedly connected with a rotary joint (403), the rotary joint (403) penetrates through the upper end face of the stirring box (1) and reaches the upper inner wall of the stirring box (1), the fixed end of the rotary joint (403) is fixedly connected between the stirring box (1), the upper end face of the stirring box (1) on one side of the servo motor (401) is provided with a nitrogen gas pump (402), the output end of the nitrogen gas pump (402) penetrates through the upper end face of the stirring box (1) and is connected between the end and the input end of the rotary joint (403), the output end of the servo motor (401) is fixedly connected with the rotary end of the rotary joint (403), the rotary end of the rotary joint (403) is fixedly connected with a stirring shaft (404), and the upper end face of the stirring box (1) is fixedly connected with a preheating structure (3) at the rear center.
2. A substantially agitated polypeptide synthesis agitator according to claim 1, wherein: A gas passage (405) is formed at the inner center of the stirring shaft (404), the gas passage (405) is connected between the output end of the rotary joint (403), the connecting rods (407) are fixedly connected to the upper centers of the two side walls of the stirring shaft (404), the two connecting rods (407) are both provided with a communication channel (409), the two connecting rods (407) are both fixedly connected with stirring blades (408) at the other ends, the upper end faces of the two stirring blades (408) are both provided with a plurality of one-way valves (410), the input ends of the plurality of one-way valves (410) are connected between the two communication channels (409), the other ends of the two stirring blades (408) are both fixedly connected with scrapers (411), and the other ends of the two scrapers (411) are both fixedly connected to the two side walls of the two stirring shafts (404).
3. A substantially agitated polypeptide synthesis agitator according to claim 1, wherein: The lower end of the stirring shaft (404) is fixedly connected with a conductive slip ring (406), the conductive slip ring (406) is fixedly connected to the lower inner wall center of the stirring box (1), the connecting lines (412) are arranged at the front and rear ends of the stirring shaft (404), a plurality of stirring rods (413) are arranged in an up-down manner at the centers of the front and rear end faces of the stirring shaft (404), the plurality of stirring rods (413) are both provided with heating wires (414), and the plurality of heating wires (414) are both fixedly connected with the two connecting lines (412).
4. A substantially agitated polypeptide synthesis agitator according to claim 1, wherein: The preheating structure (3) comprises a storage box (301), the inside of the storage box (301) is provided with a heat conduction layer (302), the upper inner wall of the lower end of the stirring box (1) is fixedly connected with an air exchange pump (304), the output end of the air exchange pump (304) penetrates the upper inner wall of the stirring box (1), the lower inner wall of the storage box (301) and one inner side wall of the storage box (301) in sequence and reaches one side of the storage box (301), and the end portion is fixedly connected with a connecting pipe (305), the output end of the connecting pipe (305) penetrates the upper center of the rear end face of the storage box (301) and reaches the inside of the storage box (301), and the end portion is fixedly connected with a heat conduction pipe (306), the heat conduction pipe (306) is wound outside the heat conduction layer (302), the end portion of the heat conduction pipe (306) is fixedly connected with an air outlet (307), the output end of the air outlet (307) penetrates the upper end face of the stirring box (1) and the lower inner wall of the storage box (301) in sequence and reaches the upper inner wall of the stirring box (1), the upper inner wall of the lower end of the stirring box (1) is fixedly connected with a discharge valve (308), and the input end of the discharge valve (308) penetrates the upper inner wall of the stirring box (1) and the lower end face of the storage box (301) in sequence and reaches the lower inner wall of the storage box (301).
5. A substantially agitated polypeptide synthesis agitator according to claim 4, wherein: The upper end face center of the storage box (301) is fixedly connected with a feeding valve (303).