Microsphere and microcarrier continuous generation equipment

Abstract

The utility model discloses microsphere and microcarrier continuous generation equipment which comprises two supporting plates, the upper surfaces of the two supporting plates are both fixedly connected with heat insulation plates, the inner surfaces of the heat insulation plates are fixedly connected with electrode connecting columns, the electrode connecting columns are fixedly connected with heating blocks, and the heating blocks are fixedly connected with heating wires. Four fixing blocks are fixedly connected to the upper surface of the heat insulation plate, a mounting plate is fixedly connected to the upper surfaces of the four fixing blocks, a mounting groove is formed in the mounting plate, an electromagnetic valve is fixedly connected to the upper surface of the mounting plate, and a connecting pipe is fixedly connected to the input end of the electromagnetic valve; and the output end of the electromagnetic valve is fixedly connected with an instillation head, the instillation head is located in the mounting groove, and the lower surface of the instillation head is fixedly connected with a splash-proof lengthened pipe. Heat generated by the heating block is effectively prevented from being disorderly dissipated to the environment through the heat insulation plate, energy consumption in long-term operation is reduced, and the sustainability of equipment operation is guaranteed from the energy utilization link.

Description

TECHNICAL FIELD

[0001] The utility model relates to microsphere microcarrier technical field, concretely is a kind of microsphere microcarrier continuous generation equipment. BACKGROUND

[0002] With the rapid development of biotechnology, pharmaceutical research and development and many fields such as chemical industry, the application of microsphere microcarrier is increasingly widespread.In the field of cell culture, microcarrier can provide larger growth surface area for cells, so that cells can better proliferate in three-dimensional space, which is crucial for large-scale cell culture to produce biological products.In the drug release system, microspheres can be used as drug carriers, and by controlling the size, composition and structure of microspheres, slow release of drugs can be achieved, improving the efficacy of drugs and reducing the toxic side effects of drugs.

[0003] The microsphere microcarrier generation equipment does not have continuous production components, so it cannot realize large-scale and uninterrupted production, and thus cannot enjoy the cost advantages in raw material procurement and energy utilization brought by mass production. UTILITY MODEL CONTENT

[0004] The utility model aims at providing a kind of microsphere microcarrier continuous generation equipment, heat generated by heat block is effectively prevented from disorderly dissipating to surrounding environment by temperature insulation board, energy consumption in long-term operation is greatly reduced, the sustainability of equipment operation is guaranteed from energy utilization link, electromagnetic valve can accurately control the material flow of connecting pipe input according to preset program, stable raw material supply guarantees the stability of microsphere microcarrier generation quality, and the rising of scrap rate and material repeated input caused by quality fluctuation are avoided.

[0005] To achieve the above object, a kind of microsphere microcarrier continuous generation equipment is provided, comprising: support plate, the number of support plate is two, the upper surface of two support plate is fixedly connected with temperature insulation board, the inner surface of temperature insulation board is fixedly connected with electrode connecting column, electrode connecting column is fixedly connected with heat block, the upper surface of temperature insulation board is fixedly connected with four fixed blocks, the upper surface of four fixed blocks is fixedly connected with mounting plate, the inside of mounting plate is provided with installation slot, the upper surface of mounting plate is fixedly connected with electromagnetic valve, the input end of electromagnetic valve is fixedly connected with connecting pipe, the output end of electromagnetic valve is fixedly connected with drip head, and drip head is located in the inside of installation slot, the lower surface of drip head is fixedly connected with splash-proof extension pipe.To microsphere microcarrier generation precision temperature control, stable feed, product quality and production continuity are guaranteed.

[0006] According to the microsphere microcarrier continuous generation equipment, the installation slot is communicated with the upper and lower sides of the mounting plate, and each heat block is provided with two electrode connecting columns.Multiple heat blocks are precisely arranged to ensure uniform heating of a large area and improve reaction efficiency.

[0007] According to the microsphere microcarrier continuous generation device, the side wall of the support plate is fixedly connected with a motor, and the output end of the motor is fixedly connected with a rotating column.

[0008] According to the microsphere microcarrier continuous generation device, the outer surface of the rotating column is fixedly connected with a first rotating roller, and the outer surface of the first rotating roller is rollingly connected with a conveying belt.

[0009] According to the microsphere microcarrier continuous generation device, the outer surface of the conveying belt is fixedly connected with two fences, and the two fences are symmetrically arranged on the left and right sides of the conveying belt.

[0010] According to the microsphere microcarrier continuous generation device, the outer surface of the conveying belt is fixedly connected with two fences, and the two fences are symmetrically arranged on the left and right sides of the conveying belt.

[0011] According to the microsphere microcarrier continuous generation device, the inner surface of the second rotating roller is rollingly connected with a second rotating roller.

[0012] Compared with the prior art, the microsphere microcarrier continuous generation device has the following beneficial effects:

[0013] The temperature insulation plate, the electrode connecting column, the heating block, the fixing block, the mounting plate, the mounting groove, the electromagnetic valve, the connecting pipe, the dripping head and the splash-proof extension pipe are arranged, heat generated by the heating block is effectively prevented from being lost to the surrounding environment in disorder through the temperature insulation plate, energy consumption in long-term operation is greatly reduced, the sustainability of equipment operation is ensured from the energy utilization link, the electromagnetic valve can accurately control the material flow input by the connecting pipe according to a preset program, stable raw material supply ensures the stability of the quality of the microsphere microcarrier, and the rising of the waste rate and repeated investment of materials caused by quality fluctuations are avoided.

[0014] Additional aspects and advantages of the present application will be given in part in the following description, and will become apparent from the following description, or will be learned by practice of the present application. BRIEF DESCRIPTION OF DRAWINGS

[0015] The utility model is further illustrated below in combination with the drawings and embodiments;

[0016] Figure 1 It is the perspective view of a kind of microsphere microcarrier continuous generation equipment of the utility model;

[0017] Figure 2 It is the front view of a kind of microsphere microcarrier continuous generation equipment of the utility model;

[0018] Figure 3 It is the section perspective view of a kind of microsphere microcarrier continuous generation equipment of the utility model;

[0019] Figure 4 It is the utility model Figure 3 Structure enlarged view in A place of middle.

[0020] In the drawing: 1, support plate;2, temperature insulation plate;3, electrode connecting column;4, heating block;5, motor;6, rotating column;7, first rotating roller;8, fixed column;9, second rotating roller;10, support leg;11, conveyer belt;12, fence;13, reaction dish;14, fixed block;15, controller;16, mounting plate;17, connecting pipe;18, electromagnetic valve;19, installation groove;20, instillation head;21, splashproof extension pipe. Specific implementation

[0021] The technical solutions in the embodiments of the utility model will be described clearly and completely below in combination with the drawings in the embodiments of the utility model, and obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor are within the protection scope of the utility model.

[0022] Please refer to Figures 1-4The utility model provides a technical scheme: a kind of microsphere microcarrier continuous generation equipment, comprising: support plate 1, the quantity of support plate 1 is two, two support plate 1 play the basic role of firm support entire equipment structure, provide solid load platform for upper component, the upper surface of two support plate 1 is all fixedly connected with heat insulation plate 2, heat insulation plate 2 can effectively block the heat generated by heating block 4 to spread outward, avoid the adverse effect of heat to other parts of equipment, ensure that equipment stable operation, the inner surface of heat insulation plate 2 is fixedly connected with electrode connecting column 3, electrode connecting column 3 is responsible for the access of external power supply, provides stable electric energy supply for heating block 4 connected with it, electrode connecting column 3 is fixedly connected with heating block 4, heating block 4 generates heat after electrification, creates suitable temperature environment for the relevant reaction in microsphere microcarrier generation process, the upper surface of heat insulation plate 2 is all fixedly connected with four fixed blocks 14, four fixed blocks 14 play the transition effect of connection support, stably fix the mounting plate 16 of upper portion, ensure the installation precision of mounting plate 16 upper component, the upper surface of four fixed blocks 14 is fixedly connected with mounting plate 16, mounting plate 16 provides unified installation plane for solenoid valve 18, connecting pipe 17 etc.

[0023] The installation groove 19 is communicated with the upper and lower sides of the installation plate 16, facilitating the docking of the drip head 20 with the lower reaction dish 13 and the smooth dripping of the liquid. The number of the heating blocks 4 is several, and each heating block 4 is provided with two electrode connecting columns 3. The plurality of heating blocks 4 work cooperatively to ensure uniform heating of a large area and meet the temperature requirements of different areas of the equipment. The sidewall of the support plate 1 is fixedly connected with the motor 5, which provides a power source for the entire conveying system and drives a series of subsequent rotating and conveying actions. The output end of the motor 5 is fixedly connected with the rotating column 6, which stably transmits the rotating force of the motor 5 to the first rotating roller 7. The outer surface of the rotating column 6 is fixedly connected with the first rotating roller 7, which serves as the driving roller of the conveying belt 11 and drives the stable operation of the conveying belt 11. The outer surface of the first rotating roller 7 is rollingly connected with the conveying belt 11, which carries the reaction dish 13 to move along the set route, realizing continuous operation. The outer surface of the conveying belt 11 is fixedly connected with two fences 12, which are symmetrically arranged on the left and right sides of the conveying belt 11. The fence 12 effectively prevents the reaction dish 13 from falling during the conveying process, ensuring the safety of the operation. The outer surface of the conveying belt 11 is in contact with the reaction dish 13, which serves as the core container for the generation of microspheres and microcarriers, and receives the dripping raw materials and completes the reaction during the conveying process. The reaction dish 13 is matched with the splash-proof extension pipe 21 to ensure that the liquid dropped by the splash-proof extension pipe 21 accurately falls into the reaction dish 13. The inner surface of the conveying belt 11 is rollingly connected with the second rotating roller 9, which cooperates with the first rotating roller 7 to keep the conveying belt 11 taut and rotate smoothly, ensuring smooth conveying. The inside of the second rotating roller 9 is fixedly connected with the fixed column 8, and the fixed column 8 is fixedly connected with the sidewalls of the two support plates 1. The fixed column 8 provides stable support for the second rotating roller 9, ensuring its rotational stability. The lower surfaces of the two support plates 1 are fixedly connected with the support legs 10, which support the entire equipment to a certain distance from the ground, avoiding damage to the equipment caused by ground moisture, etc. The upper part of the support leg 10 is provided with the controller 15, which is fixedly connected with the upper surface of the installation plate 16. The controller 15 is responsible for intelligent control of key components such as the motor 5 and the electromagnetic valve 18, coordinates the orderly work of each component, and ensures the efficiency and accuracy of the continuous generation process of microspheres and microcarriers.

[0024] Working principle: connect the external power supply to the electrode connecting column 3, power the heating block 4, and turn on the controller 15, connect the container containing the liquid raw material to the connecting pipe 17, set the heating temperature of the heating block 4 through the controller 15, accurately adjust the working state of the heating block 4, make it warm up to the predetermined temperature, and the temperature insulation plate 2 plays a role at this time, operate on the controller 15, start the motor 5, the motor 5 drives the rotating column 6 to rotate, and then drives the first rotating roller 7 to rotate, the conveying belt 11 starts to run at a constant speed, the two side fences 12 can effectively block the reaction dish 13 from falling off, at the same time, the second rotating roller 9 is matched with the rotation under the support of the fixed column 8, keeps the tension of the conveying belt 11, opens the control switch of the electromagnetic valve 18 to standby state, at this time, the liquid in the connecting pipe 17 is close to the electromagnetic valve 18 under the action of external pressure, but it is controlled by the electromagnetic valve 18 and has not been dropped yet, the splash-proof extension pipe 21 under the dripping head 20 has been aligned with the reaction dish 13 moving on the conveying belt 11, with the operation of the conveying belt 11, when the reaction dish 13 moves to the position directly below the dripping head 20, the electromagnetic valve 18 is accurately controlled to open through the controller 15, the liquid raw material is dripped into the reaction dish 13 through the dripping head 20 and the splash-proof extension pipe 21 from the connecting pipe 17 and the electromagnetic valve 18, the reaction dish 13 continues to move forward under the driving of the conveying belt 11, enters the suitable temperature area created by the heating block 4, and starts the generation reaction of the microsphere microcarrier, in the whole process, the controller 15 continuously monitors the running parameters of each part, such as temperature, dripping flow, conveying belt speed, etc., to ensure that the equipment can stably and efficiently generate microsphere microcarrier according to the preset process.

[0025] The above embodiment of the utility model is described in detail in combination with the drawings, but the utility model is not limited to the above embodiment, and various changes can be made within the knowledge range possessed by ordinary skilled persons in the technical field without departing from the purpose of the utility model.

Claims

1. A microsphere microcarrier continuous generation apparatus comprising: Supporting plate (1), the number of the supporting plate (1) is two, it is characterized by: the upper surface of two the supporting plate (1) is fixedly connected with the heat insulation board (2), the inner surface of the heat insulation board (2) is fixedly connected with the electrode connecting column (3), the electrode connecting column (3) is fixedly connected with the heat block (4), the upper surface of the heat insulation board (2) is fixedly connected with four fixed blocks (14), the upper surface of four the fixed block (14) is fixedly connected with the mounting plate (16), the inside of the mounting plate (16) is provided with the installation groove (19), the upper surface of the mounting plate (16) is fixedly connected with the electromagnetic valve (18), the input end of the electromagnetic valve (18) is fixedly connected with the connecting pipe (17), the output end of the electromagnetic valve (18) is fixedly connected with the infusion head (20), and the infusion head (20) is located in the inside of installation groove (19), the lower surface of the infusion head (20) is fixedly connected with the splashproof extension pipe (21).

2. A microsphere microcarrier continuous generation apparatus as claimed in claim 1, characterized in that: The installation groove (19) is in communication with the upper and lower sides of the mounting plate (16), and the number of the heat block (4) is several, two electrode connecting columns (3) are arranged on each heat block (4).

3. A microsphere microcarrier continuous generation apparatus as claimed in claim 1, characterized in that: The side wall of the supporting plate (1) is fixedly connected with the motor (5), and the output end of the motor (5) is fixedly connected with the rotating column (6).

4. A microsphere microcarrier continuous generation apparatus as claimed in claim 3, characterised in that: The outer surface of the rotating column (6) is fixedly connected with the first rotating roller (7), and the outer surface of the first rotating roller (7) is rollingly connected with the conveying belt (11).

5. A microsphere microcarrier continuous generation apparatus as claimed in claim 4, characterised in that: The outer surface of the conveying belt (11) is fixedly connected with two fences (12), and the two fences (12) are symmetrically arranged on the left and right sides of the conveying belt (11).

6. A microsphere microcarrier continuous generation apparatus as claimed in claim 5, characterised in that: The outer surface of the conveying belt (11) is in contact with the reaction vessel (13), the reaction vessel (13) is matched with the splashproof extension pipe (21), and the inner surface of the conveying belt (11) is rollingly connected with the second rotating roller (9).

7. A microsphere microcarrier continuous generation apparatus as claimed in claim 6, characterised in that: The inside of the second rotating roller (9) is fixedly connected with the fixed column (8), and the fixed column (8) is fixedly connected with the side wall of the two supporting plates (1), the lower surface of the two supporting plates (1) is fixedly connected with the supporting leg (10), the upper side of the supporting leg (10) is provided with the controller (15), and the controller (15) is fixedly connected with the upper surface of the mounting plate (16).

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