Swing angle mechanism and purification device thereof
By inclining and tilting the swing angle mechanism, the problem of uneven mixing of magnetic bead reagents was solved, achieving uniform distribution of the solution and efficient reaction, thus improving production efficiency.
Patent Information
- Application Number
- CN202423086022.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-12
- Publication Date
- 2026-01-20
- Estimated Expiration
- 2034-12-12
AI Technical Summary
In the existing technology, magnetic bead reagents have problems such as difficulty in mixing when the frequency is low, and easy to affect the product when the frequency is high during the mixing process. They are also prone to liquid splashing and bubbles.
The tilting mechanism, through the cooperation of the tilting angle unit and the drive unit, realizes the tilting and tilting angle of the spin reaction unit, ensuring that the liquid is fully mixed, and the reaction liquid is thrown out to the waste liquid collection tank under the action of centrifugal force.
This ensures thorough mixing of the solution, guarantees the uniformity of all components in the reaction solution, improves production efficiency, and reduces experimental variations.
Smart Images

Figure CN223810995U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to purification equipment technical field especially, it relates to swing angle mechanism and its purification device. BACKGROUND
[0002] The magnetic bead reagent is widely used in sample analysis field. The magnetic bead reagent usually includes magnetic bead, its marker and buffer, and is absorbed by corresponding reagent suction device when using, and is sent to corresponding reaction container. In the prior art, there is the technical problem of mixing small volume liquid, low frequency and not easy to mix magnetic beads, high frequency and easy to affect product, and liquid splashing and bubble etc. CONTENT OF UTILITY MODEL
[0003] To solve the above technical problem, one of the technical solutions of the utility model is: swing angle mechanism, the mechanism is used to tilt a plurality of spin reaction units on the purification device to a specified angle, improve mixing effect, the mechanism includes:
[0004] Tilt angle unit 1 is used to tilt a plurality of spin reaction units installed on it;
[0005] Driving unit 2 is used to drive the rotation of tilt angle unit 1;The driving end of driving unit 2 is connected with the rotating end of tilt angle unit 1.
[0006] Wherein, driving unit 2 is installed on the base of purification device.
[0007] Further, the tilt angle unit 1 includes:
[0008] Rotary disc 101 is provided with at least one chute 102 on it;
[0009] Mounting round plate 103 is fixedly installed on the upper end of the cylinder of purification device;The edge of mounting round plate 103 is provided with a plurality of inward grooves 104;
[0010] At least one group of tilt mounting seat 105, each group is on the two sides of inward groove 104 of mounting round plate 103;
[0011] At least two swing angle shafts 106, one end of each is installed on the corresponding tilt mounting seat 105, and the other end is installed on the surface of spin reaction unit;
[0012] At least two gears 107, each is fixedly installed on swing angle shaft 106;
[0013] At least two slide rails 108, which are fixedly installed on the two sides of inward groove 104;
[0014] At least two racks 109, which are slidingly installed on the corresponding slide rails 108;
[0015] at least two connecting rods 1010, each of which is fixedly installed at one end on the rack 109;
[0016] at least one slide column 1011, which is located in the slide groove 102 and slides along the length direction of the slide groove 102.
[0017] Further, the other end of each connecting rod 1010 is hingedly connected to the slide column 1011; and each gear 107 is engaged with the corresponding rack 109.
[0018] When the rotating disc 101 rotates, the slide column 1011 slides along the length direction of the slide groove 102, and the two racks 109 are synchronously moved along the length direction of the slide rail 108 by the connecting rod 1010, so as to drive the gear 107 to rotate along the length direction of the rack 109, thereby realizing the outward swing angle of the self-rotation reaction unit.
[0019] Further, the driving unit 2 comprises:
[0020] a servo electric actuator 201, which is fixedly installed at the lower end of the cylinder of the purification device;
[0021] a telescopic plate 202, which is located below the cylinder of the purification device; the telescopic end of the servo electric actuator 201 is fixedly connected to the telescopic plate 202;
[0022] at least one telescopic column 203, one end of which is installed on the telescopic plate 202;
[0023] a spiral telescopic hollow column 204, which is located in the purification device; at least one spiral block 205 is arranged on the outer surface of the spiral telescopic hollow column 204;
[0024] a rotating hollow column 206, which is located outside the spiral telescopic hollow column 204; a spiral groove 207 is arranged at the lower end of the inner side of the rotating hollow column 206;
[0025] wherein the other end of the telescopic column 203 extends into the cylinder of the purification device and is installed on the outer surface of the spiral telescopic hollow column 204; the spiral block 205 is embedded in the spiral groove 207;
[0026] The servo electric actuator 201 drives the telescopic plate 202 to move up and down, and the telescopic plate 202 drives the spiral telescopic hollow column 204 to spiral up and down, thereby driving the rotating hollow column 206 to rotate.
[0027] Since the servo electric actuator 201 can accurately stop at any position within the telescopic stroke, the rotating hollow column 206 can be fixed at any angle.
[0028] Further, the other end of the telescopic column 203 is installed on the outer surface of the screw telescopic hollow column 204 through the bearing seat 208, so that the rotation of the screw telescopic hollow column 204 and the telescopic movement of the telescopic column 203 do not affect each other.
[0029] Further, the rotating disc 101 is installed on the upper end of the rotating hollow column 206; the rotation of the rotating disc 101 is realized.
[0030] Another technical scheme adopted by the utility model is: a purification device, which comprises the swing angle mechanism.
[0031] The utility model has the advantages and positive effects that: by setting the inclination angle unit, when mixing, the swing angle mechanism inclines the self-rotation reaction unit inward by 45 degrees to mix the liquid; after mixing and reacting for a period of time, the swing angle mechanism inclines the self-rotation reaction unit outward by 45-75 degrees, and under the action of centrifugal force, the liquid in the reaction tube is thrown out to the waste liquid collecting groove of the purification device.
[0032] The solution is fully mixed, the uniformity of various components in the reaction liquid is ensured, the various components are evenly distributed, the reaction is more facilitated, the production efficiency is improved, and the experimental difference is reduced. BRIEF DESCRIPTION OF DRAWINGS
[0033] Figure 1 It is a structure schematic view of the swing angle mechanism;
[0034] Figure 2 It is a position relation view of the screw telescopic hollow column and the rotating hollow column;
[0035] Figure 3 It is a structure schematic view of the rotating hollow column;
[0036] Figure 4 It is a structure schematic view of the screw telescopic hollow column;
[0037] Figure 5 It is a top view of the swing angle mechanism;
[0038] Figure 6 It is a structure schematic view of the swing angle mechanism;
[0039] Figure 7 It is a structure schematic view of the purification device;
[0040] In the figure: 1, tilt angle unit; 101, rotating disc; 102, sliding groove; 103, mounting round plate; 104, inward fluting; 105, tilt mounting seat; 106, swing angle shaft; 107, gear; 108, sliding rail; 109, rack; 1010, connecting rod; 1011, sliding column; 2, driving unit; 201, servo electric actuator; 202, telescopic plate; 203, telescopic column; 204, spiral telescopic hollow column; 205, spiral block; 206, rotating hollow column; 207, spiral groove; 208, bearing seat. DETAILED DESCRIPTION
[0041] In order to better understand the present application, the present application will be further described below in combination with specific embodiments and drawings.
[0042] Embodiment 1
[0043] As shown in the figure, the swing angle mechanism is used for tilting a plurality of spin reaction units on the purification device by a specified angle to improve the mixing effect, and the mechanism comprises: Figures 1-6
[0044] The tilt angle unit 1 is used for realizing the tilting of a plurality of spin reaction units mounted thereon.
[0045] Specifically, the tilt angle unit 1 comprises:
[0046] The rotating disc 101 is provided with at least one sliding groove 102;
[0047] The mounting round plate 103 is fixedly mounted on the upper end of the cylinder of the purification device, and a plurality of inward fluting 104 are arranged at the edge of the mounting round plate 103;
[0048] At least one group of tilt mounting seats 105 is arranged on both sides of the inward fluting 104 of the mounting round plate 103;
[0049] At least two swing angle shafts 106 are arranged, one end of each swing angle shaft 106 is mounted on the corresponding tilt mounting seat 105, and the other end is mounted on the surface of the spin reaction unit;
[0050] At least two gears 107 are fixedly mounted on the swing angle shaft 106;
[0051] At least two sliding rails 108 are fixedly mounted on both sides of the inward fluting 104;
[0052] At least two racks 109 are slidingly mounted on the corresponding sliding rails 108;
[0053] At least two connecting rods 1010 are fixedly mounted on the rack 109;
[0054] At least one slide post 1011 is located in the slide groove 102 and slides along the length direction of the slide groove 102.
[0055] Specifically, the spin reaction unit includes but is not limited to the magnetic bead centrifugal reaction device in the prior art.
[0056] Further, the other end of each connecting rod 1010 is hingedly connected with the slide post 1011; and each gear 107 is engaged with the corresponding rack 109.
[0057] A driving unit 2 is configured to drive the rotation of the tilt angle unit 1; and the driving end of the driving unit 2 is connected with the rotating end of the tilt angle unit 1.
[0058] The driving unit 2 is installed on the base of the purification device.
[0059] Specifically, the driving unit 2 includes:
[0060] A servo electric actuator 201 is fixedly installed at the lower end of the cylinder of the purification device;
[0061] A telescopic plate 202 is located below the cylinder of the purification device; and the telescopic end of the servo electric actuator 201 is fixedly connected with the telescopic plate 202.
[0062] At least one telescopic post 203 is installed at one end of the telescopic plate 202.
[0063] A spiral telescopic hollow post 204 is located in the purification device; and at least one spiral block 205 is arranged on the outer surface of the spiral telescopic hollow post 204.
[0064] A rotating hollow post 206 is located outside the spiral telescopic hollow post 204; and a spiral groove 207 is arranged at the lower end of the inner side of the rotating hollow post 206.
[0065] Further, the other end of the telescopic post 203 extends into the cylinder of the purification device and is installed on the outer surface of the spiral telescopic hollow post 204; and the spiral block 205 is embedded in the spiral groove 207.
[0066] Further, the other end of the telescopic post 203 is installed on the outer surface of the spiral telescopic hollow post 204 through a bearing seat 208, so that the rotation of the spiral telescopic hollow post 204 and the telescopic movement of the telescopic post 203 do not affect each other.
[0067] Further, the rotating disc 101 is installed at the upper end of the rotating hollow post 206, so as to realize the rotation of the rotating disc 101.
[0068] Its working process: The servo electric actuator 201 drives the telescopic plate 202 to move up and down, the telescopic plate 202 drives the spiral telescopic hollow column 204 to move up and down spirally, and then drives the rotating hollow column 206 to rotate.
[0069] Because the servo electric actuator 201 can precisely stop at any position within its extension and retraction stroke, the rotating hollow column 206 can be fixed at any angle.
[0070] When the rotating disk 101 rotates, the sliding column 1011 slides along the length direction of the sliding groove 102, and drives the two racks 109 to move synchronously along the length direction of the slide rail 108 through the connecting rod 1010, which drives the gear 107 to rotate along the length direction of the rack 109, thereby realizing the inward or outward swing angle of the spin reaction unit.
[0071] By setting the tilt angle unit, during mixing, the swing angle mechanism tilts the spin reaction unit inward by 45 degrees to mix the liquid; after mixing and reacting for a period of time, the swing angle mechanism tilts the spin unit outward by 45 to 75 degrees, and under the action of centrifugal force, the liquid in the reaction tube is thrown out to the waste liquid collection tank of the purification device.
[0072] Thoroughly mixing the solution ensures the uniformity and even distribution of all components in the reaction solution, which is more conducive to promoting the reaction, improving production efficiency, and reducing experimental variability.
[0073] Example 2
[0074] like Figure 7 As shown, the purification device includes the swing angle mechanism described in Example 1 above.
[0075] The embodiments of this utility model have been described in detail above, but the content described is only a preferred embodiment of this utility model and should not be considered as limiting the scope of implementation of this utility model. All equivalent changes and improvements made within the scope of this utility model should still fall within the scope of this patent.
Claims
1. A swing angle mechanism, characterized in that: This mechanism is used to tilt multiple spin reaction units on a purification device at a specified angle to improve mixing. The mechanism includes: Tilting angle unit (1) is used to tilt multiple spin reaction units mounted thereon; A driving unit (2) is used to drive the rotation of the tilt angle unit (1); the driving end of the driving unit (2) is connected to the rotating end of the tilt angle unit (1). The drive unit (2) is installed on the base of the purification device.
2. The swing angle mechanism according to claim 1, characterized in that: The tilt angle unit (1) includes: A rotating disk (101); at least one groove (102) is provided on the rotating disk (101); A mounting plate (103) is fixedly installed on the upper end of the cylinder of the purification device; the mounting plate (103) has multiple inward grooves (104) at its edge; At least one set of inclined mounting seats (105), each set being on both sides of the inward slot (104) of the mounting disc (103); At least two pendulum shafts (106), one end of each of which is mounted on a corresponding tilting mount (105) and the other end is mounted on the surface of the spin reaction unit; At least two gears (107), each of which is fixedly mounted on the swing shaft (106); At least two slide rails (108) are fixedly installed on both sides of the inward slot (104); At least two racks (109) are slidably mounted on corresponding slide rails (108); At least two connecting rods (1010), one end of each of which is fixedly mounted on a rack (109); At least one sliding post (1011) is located in the groove (102) and slides along the length of the groove (102).
3. The swing angle mechanism according to claim 2, characterized in that: The other end of each connecting rod (1010) is hinged to the slide (1011); each gear (107) meshes with the corresponding rack (109); When the rotating disk (101) rotates, the sliding column (1011) slides along the length direction of the sliding groove (102), and drives the two racks (109) to move synchronously along the length direction of the slide rail (108) through the connecting rod (1010), which in turn drives the gear (107) to rotate along the length direction of the rack (109), thereby realizing the swing angle of the spin reaction unit.
4. The swing angle mechanism according to claim 3, characterized in that: The drive unit (2) includes: A servo-electric actuator (201) is fixedly installed at the lower end of the cylinder of the purification device; The telescopic plate (202) is located below the outer shell of the purification device; the telescopic end of the servo electric actuator (201) is fixedly connected to the telescopic plate (202); At least one telescopic column (203) has one end mounted on the telescopic plate (202); A spiral telescopic hollow column (204) is located inside the purification device; at least one spiral block (205) is provided on the outer surface of the spiral telescopic hollow column (204); A rotating hollow column (206) is located outside the spiral telescopic hollow column (204); the lower inner end of the rotating hollow column (206) is provided with a spiral groove (207); The other end of the telescopic column (203) extends into the cylinder of the purification device and is installed on the outer surface of the spiral telescopic hollow column (204); the spiral block (205) is embedded in the spiral groove (207); The servo electric actuator (201) drives the telescopic plate (202) to move up and down, and the telescopic plate (202) drives the spiral telescopic hollow column (204) to move up and down spirally, thereby driving the rotating hollow column (206) to rotate. Since the servo electric actuator (201) can accurately stop at any position within its extension and retraction stroke, the rotating hollow column (206) can be fixed at any angle.
5. The swing angle mechanism according to claim 4, characterized in that: The other end of the telescopic column (203) is installed on the outer surface of the spiral telescopic hollow column (204) through the bearing seat (208), so that the rotation of the spiral telescopic hollow column (204) and the telescopic movement of the telescopic column (203) do not affect each other.
6. The swing angle mechanism according to claim 5, characterized in that: The rotating disk (101) is installed at the upper end of the rotating hollow column (206) to realize the rotation of the rotating disk (101).
7. A purification apparatus, characterized in that: The device includes the swing angle mechanism as described in any one of claims 1-5.