Efficient sample pretreatment device for mass spectrometric detection

Abstract

The utility model relates to the technical field of sample mixing equipment, and discloses a high-efficiency sample pretreatment device for mass spectrum detection, which comprises a mounting table on which a combined high-efficiency rotary mixing structure is mounted; the combined type efficient rotating mixing structure comprises an equipment box, a mounting cavity, a rotating base, a placing bracket, a combined rod, an inserting groove, a sealing sleeve, a mounting bracket, a lifting push rod, a rotating sleeve, an equipment top cover, a servo motor, a rotating inserting rod and a positioning assembly. The utility model solves the problems that the existing sample dissolving and mixing method generally depends on manual operation or a simple mechanical stirring device, the manual operation is time-consuming and the mixing uniformity is difficult to guarantee, the efficiency is low, the treatment results of samples of different operators or different batches possibly have large differences, the sample consistency is influenced, and the sample dissolving and mixing efficiency is low. And external pollutants are easy to introduce through open type operation, so that the purity of the sample is influenced.

Description

TECHNICAL FIELD

[0001] The utility model relates to sample mixing equipment technical field, specifically for a kind of high-efficiency sample pretreatment device for mass spectrometry. BACKGROUND

[0002] Mass spectrometry is a technique for analyzing chemical components in a sample by measuring the mass-to-charge ratio of ions to determine the mass and structure of molecules. In mass spectrometry, sample pretreatment is a critical step to ensure the accuracy and reliability of the analysis results. Sample pretreatment usually includes processes such as sample dissolution, mixing, separation, and purification. Among them, sample dissolution and mixing are the foundation and important links. Efficient sample dissolution and mixing can ensure that the target components in the sample are uniformly distributed, thereby improving the sensitivity and resolution of mass spectrometry.

[0003] The existing sample dissolution and mixing methods usually rely on manual operation or simple mechanical stirring devices. Manual operation is time-consuming and difficult to ensure uniform mixing, resulting in low efficiency. Different operators or different batches of sample processing results may have large differences, affecting sample consistency. Open operation is easy to introduce external pollutants, affecting sample purity. SUMMARY

[0004] To solve the above technical problems, the utility model realizes the following technical scheme:

[0005] A high-efficiency sample pretreatment device for mass spectrometry, comprising: a mounting table, a combined high-efficiency rotary mixing structure is installed on the mounting table;

[0006] The combined high-efficiency rotary mixing structure comprises: a device box, a mounting cavity, a rotary base, a placement bracket, a combination rod, a plug-in slot, a sealing sleeve, a mounting bracket, a lifting push rod, a rotary sleeve, a device top cover, a servo motor, a rotary plug rod, and a positioning assembly;

[0007] The device box is installed on the wall surface of the mounting table, the mounting cavity is opened in the device box, the rotary base is installed on the lower wall surface in the mounting cavity, the placement bracket is installed on the rotary base, the combination rod is installed at the middle position of the placement bracket, the plug-in slot is opened at the top end position of the combination rod, the sealing sleeve is installed on the top wall surface of the device box, the mounting bracket is installed at the rear position of the device box, the lifting push rod is installed on the mounting bracket, the rotary sleeve is installed on the output end of the lifting push rod, the device top cover is installed on the rotary sleeve, the servo motor is installed on the device top cover with the output end penetrating downward, the rotary plug rod is installed on the output end of the servo motor, and the positioning assembly is installed on the device box and the device top cover.

[0008] Preferably, a rubber sleeve is installed on the placement bracket.

[0009] Preferably, a reinforcing rib plate is installed on the mounting bracket.

[0010] Preferably, the device top cover is installed on the rotating sleeve through the connecting rod.

[0011] Preferably, the servo motor is installed on the device top cover through the fixing bolt.

[0012] Preferably, the positioning assembly comprises a pair of mounting blocks, a pair of positioning rods, a pair of combination racks and two pairs of combination jacks.

[0013] The pair of mounting blocks are installed on both sides of the device top cover, the pair of positioning rods are installed on the pair of mounting blocks, the pair of combination racks are installed on the two side walls of the device box, and the two pairs of combination jacks are formed in the pair of combination racks.

[0014] Beneficial effects

[0015] The utility model provides a high -efficient sample pretreatment device for mass spectrum detects possesses the following beneficial effects:

[0016] The scheme uses the combined high -efficient rotary mixing structure, carries out high -efficient rotary mixing through the combined drive structure, mixes and dissolves the sample, guarantees the operation efficiency, guarantees the consistency of multiple samples simultaneously, guarantees the subsequent detection result, solves the sample dissolution and mixing method of existing usually relying on manual operation or simple mechanical stirring device, manual operation is time -consuming and is difficult to guarantee mixing homogeneity, causes efficiency to be lower, and the sample processing result of different operators or different batches can exist larger difference, influences sample consistency, and the open -type operation is easy to introduce the external contaminant, influences sample purity's problem. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 It is a front view three -dimensional structure schematic diagram of high -efficient sample pretreatment device for mass spectrum detection of the utility model.

[0018] Figure 2 It is a bottom view three -dimensional structure schematic diagram of high -efficient sample pretreatment device for mass spectrum detection of the utility model.

[0019] Figure 3 It is a front view partial sectional view three -dimensional structure schematic diagram of high -efficient sample pretreatment device for mass spectrum detection of the utility model.

[0020] Figure 4 It is a front view partial sectional view structure schematic diagram of high -efficient sample pretreatment device for mass spectrum detection of the utility model.

[0021] In the figure: 1 - installation platform; 2 - equipment box; 3 - installation cavity; 4 - rotating base; 5 - placing support; 6 - combined rod; 7 - plug-in slot; 8 - sealing sleeve; 9 - mounting support; 10 - lifting push rod; 11 - rotating sleeve; 12 - equipment top cover; 13 - servo motor; 14 - rotating plug; 15 - rubber sleeve; 16 - reinforcing rib plate; 17 - connecting rod; 18 - fixing bolt; 19 - mounting block; 20 - positioning rod; 21 - combined frame; 22 - combined jack. DETAILED DESCRIPTION

[0022] Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without making creative labor belong to the scope of protection of the utility model.

[0023] Embodiment: please refer to Figures 1-4 The utility model provides a technical scheme:

[0024] A high-efficiency sample pretreatment device for mass spectrometric detection, considering that the existing manual sample shaking and mixing efficiency is low, multiple shaking and mixing cannot guarantee the consistency of each sample, and is prone to cause errors in subsequent mass spectrometric detection, based on the above content, the case sets the following technical means:

[0025] Specifically, the device at least includes installation platform 1, equipment box 2, installation cavity 3, rotating base 4, placing support 5, combined rod 6, plug-in slot 7, sealing sleeve 8, mounting support 9, lifting push rod 10, rotating sleeve 11, equipment top cover 12, servo motor 13, rotating plug 14 and positioning assembly.

[0026] The positioning assembly comprises: a pair of mounting blocks 19, a pair of positioning rods 20, a pair of combined frames 21 and two pairs of combined jacks 22.

[0027] More specifically, the equipment box 2 is installed on the upper wall of the installation platform 1, the installation cavity 3 is opened in the equipment box 2, the rotating base 4 is installed on the lower wall in the installation cavity 3, the placing support 5 is installed on the rotating base 4, the combined rod 6 is installed at the middle position of the placing support 5, the plug-in slot 7 is opened at the top end position of the combined rod 6, the sealing sleeve 8 is installed on the upper wall of the top of the equipment box 2, the mounting support 9 is installed at the rear position of the equipment box 2, the lifting push rod 10 is installed on the mounting support 9, the rotating sleeve 11 is installed on the output end of the lifting push rod 10, the equipment top cover 12 is installed on the rotating sleeve 11, the servo motor 13 is installed on the equipment top cover 12 and the output end penetrates downward, the rotating plug 14 is installed on the output end of the servo motor 13, and the positioning assembly is installed on the equipment box 2 and the equipment top cover 12.

[0028] A pair of mounting blocks 19 are installed on both sides of the equipment top cover 12, a pair of positioning rods 20 are installed on the pair of mounting blocks 19, a pair of combination frames 21 are installed on both sides of the equipment box 2, and two pairs of combination sockets 22 are opened on the pair of combination frames 21.

[0029] In the specific implementation process, a rubber sleeve 15 is further installed on the placement bracket 5 to protect the sample tube, and its flexibility allows it to be used for test tubes of different sizes and specifications.

[0030] In the specific implementation process, furthermore, reinforcing ribs 16 are installed on the mounting bracket 9 to strengthen the support of the mounting bracket 9 and increase the stability of the support.

[0031] In the specific implementation process, the top cover 12 of the equipment is further installed on the rotating sleeve 11 through the connecting rod 17, so that the top cover 12 of the equipment and the rotating sleeve 11 are connected. The rotating sleeve 11 drives the top cover 12 of the equipment and the equipment installed on it to rotate, which facilitates the placement and retrieval of sample tubes.

[0032] In the specific implementation process, the servo motor 13 is further installed on the top cover 12 of the equipment by fixing bolts 18. The servo motor 13 is firmly fixed by the stable installation effect of the fixing bolts 18 to ensure the installation of the equipment.

[0033] Mounting platform 1 supports the main body of the equipment. During use, solvent tubes containing samples are inserted and fixed onto the placement bracket 5. The position of the top cover 12 is adjusted by rotating sleeve 11 to align it with the equipment box 2. The output end of the lifting push rod 10 mounted on mounting bracket 9 is retracted, allowing the positioning rod 20, mounted on the top cover 12 via mounting block 19, to be inserted into the combination insertion hole 22 on the combination frame 21 for positioning and guidance, ensuring alignment. The output end of the lifting push rod 10 continues to retract, causing the rotating insertion rod 14 to be inserted into the insertion slot 7 at the top of the combination rod 6, achieving the combination connection. The servo motor 13 mounted on the top cover 12 reciprocates, and the combination rod 6 and rotating insertion rod 14, together with the rotating base 4, drive the placement bracket 5 to reciprocate at high speed, thereby ensuring thorough mixing and dissolution of the samples and achieving sample pretreatment. When placing or removing sample tubes, the top cover 12 is rotated to the side via rotating sleeve 11 for easy placement and removal of sample tubes.

[0034] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A high efficiency sample preparation device for mass spectrometric detection, comprising: The installation table (1) is characterized in that the combined high-efficiency rotary mixing structure is installed on the installation table (1). The combined high-efficiency rotary mixing structure comprises a device box (2), an installation cavity (3), a rotary base (4), a placing support (5), a combination rod (6), a plug-in slot (7), a sealing sleeve (8), an installation support (9), a lifting push rod (10), a rotary sleeve (11), a device top cover (12), a servo motor (13), a rotary plug rod (14), and a positioning assembly. The device box (2) is installed on the upper wall of the installation table (1), the installation cavity (3) is arranged in the device box (2), the rotary base (4) is installed on the lower wall of the installation cavity (3), the placing support (5) is installed on the rotary base (4), the combination rod (6) is installed at the middle position of the placing support (5), the plug-in slot (7) is arranged at the top end of the combination rod (6), the sealing sleeve (8) is installed on the upper wall of the top of the device box (2), the installation support (9) is installed at the rear of the device box (2), the lifting push rod (10) is installed on the installation support (9), the rotary sleeve (11) is installed on the output end of the lifting push rod (10), the device top cover (12) is installed on the rotary sleeve (11), the servo motor (13) is installed on the device top cover (12) and the output end thereof extends downward, the rotary plug rod (14) is installed on the output end of the servo motor (13), and the positioning assembly is installed on the device box (2) and the device top cover (12).

2. The high efficient sample pretreatment device for mass spectrometry of claim 1, wherein, The placing support (5) is provided with a rubber sleeve (15).

3. The high efficient sample pretreatment device for mass spectrum detection according to claim 1, characterized in that, The installation support (9) is provided with a reinforcing rib plate (16).

4. The high efficient sample pretreatment device for mass spectrum detection according to claim 1, characterized in that, The device top cover (12) is installed on the rotary sleeve (11) through a connecting rod (17).

5. The high efficient sample pretreatment device for mass spectrometry of claim 1, wherein, The servo motor (13) is installed on the device top cover (12) through a fixing bolt (18).

6. The high efficient sample pretreatment device for mass spectrum detection according to claim 1, characterized in that, The positioning assembly comprises a pair of installation blocks (19), a pair of positioning rods (20), a pair of combination racks (21), and two pairs of combination jacks (22). The pair of installation blocks (19) are installed on the two sides of the device top cover (12), the pair of positioning rods (20) are installed on the pair of installation blocks (19), the pair of combination racks (21) are installed on the two side walls of the device box (2), and the two pairs of combination jacks (22) are arranged on the pair of combination racks (21).

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