Device capable of simultaneously carrying out tissue cell collection and confocal imaging

Abstract

The utility model discloses a device capable of simultaneously carrying out tissue cell collection and confocal imaging, which comprises a workbench and a puncture needle, one side of the workbench is provided with a collection detection mechanism, the collection detection mechanism comprises a transverse plate, one side of the transverse plate is fixedly connected with a hollow block, and the hollow block is fixedly connected with the puncture needle. An electric telescopic rod is fixedly connected to the front face of the hollow block, a connecting frame is fixedly connected to one side of the electric telescopic rod, and a sealing plate is fixedly connected to one side of the connecting frame. By arranging a collecting and detecting mechanism, starting an electric telescopic rod, driving a connecting frame to move by the electric telescopic rod, and driving a sealing plate to move by the connecting frame, negative pressure suction work is performed, cells are sucked into an inner cavity of a hollow block, and after part of the cells are sucked, the electric telescopic rod can be controlled to contract, so that the cells are pushed into an inner cavity of a fixed pipe through the sealing plate; cells are discharged to the top of the bearing plate through the fixing pipe, meanwhile, the bearing plate is moved to a detection position, and detection work is conducted through the detection probe.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical instrument technical field, concretely is a device that can carry out tissue cell collection and confocal imaging simultaneously. BACKGROUND

[0002] Surgery is commonly known as operation, which is a medical technology that medical institutions and their medical staffs carry out medical operations such as removing diseased tissues, repairing damage, reconstructing form or function, transplanting cell tissues or organs, and implanting medical devices on a part of human body for the purpose of diagnosing or treating diseases. Surgery should be based on clinical research and have definite safety and effectiveness. In some surgical procedures, tissue cells need to be extracted for detection.

[0003] According to the patent document CN221460374U, a natural cavity epithelial tissue cell collection device is disclosed, which includes a suction device and a collection needle. The collection needle includes a needle tube and an expansion head. The expansion head is arranged at one end of the needle tube, and the other end of the needle tube is connected with the suction device. The expansion head has a cavity inside, and the center hole of the needle tube is in communication with the cavity. The outer surface of the expansion head is provided with a plurality of through holes in communication with the cavity. The plurality of through holes are arranged around the axis of the center hole of the expansion head, and the cross section of the expansion head perpendicular to the axis of the center hole is larger than the diameter of the needle tube. The utility model has no effect on experimental animals, can take samples from the same natural cavity of the animal continuously and repeatedly at different times, and has low experimental cost. In addition, the through holes are arranged around the expansion head to make the experimental sampling more convenient.

[0004] The conventional tissue cell collection device cannot accurately sample diseased cells in daily use, which requires a long time to find diseased cells, thus prolonging the operation time and increasing the risk of surgery, and cannot meet the use requirements. UTILITY MODEL CONTENTS

[0005] The utility model aims to provide a device that can collect tissue cells and perform confocal imaging simultaneously to solve the problem that the conventional tissue cell collection device cannot accurately sample diseased cells in daily use, which requires a long time to find diseased cells, thus prolonging the operation time and increasing the risk of surgery, and cannot meet the use requirements.

[0006] In order to achieve the above object, the utility model provides the following technical scheme: a device that can collect tissue cells and carry out confocal imaging simultaneously, including work table and puncture needle, one side of the work table is provided with collection detection mechanism, the collection detection mechanism includes horizontal plate, one side of the horizontal plate is fixedly connected with hollow block, the front of the hollow block is fixedly connected with electric telescopic handle, one side of the electric telescopic handle is fixedly connected with connecting frame, one side of the connecting frame is fixedly connected with sealing plate, the left side of the bottom of the hollow block is connected with first check valve, one side of the first check valve is connected with swan neck pipe, the right side of the bottom of the hollow block is connected with second check valve, one side of the second check valve is connected with fixed tube, the right side of the top of the work table is fixedly connected with detection probe, one side of the detection probe is provided with bearing plate, the inner chamber of the puncture needle is provided with confocal probe, one side of the confocal probe is fixedly connected with optical fiber.

[0007] Preferably, the other side of the work table is provided with a cleaning mechanism, the cleaning mechanism includes a box, the bottom of the box is fixedly connected with the horizontal plate, the right side of the bottom of the box is communicated with a connecting pipe, the left side of the bottom of the box is communicated with a pump, one side of the pump is communicated with a discharge pipe, one side of the discharge pipe is communicated with a spray head, and the middle shaft of the top of the work table is fixedly connected with a collection frame.

[0008] Preferably, the front side of the bottom of the work table is fixedly connected with a shell, the front side of the inner chamber of the shell is fixedly connected with a toothed plate, one side of the toothed plate is engaged with a gear, one side of the gear is fixedly connected with a motor, one side of the motor is fixedly connected with a sliding sleeve, one side of the sliding sleeve is fixedly connected with a fixing frame, and one side of the fixing frame is fixedly connected with a bearing plate.

[0009] Preferably, the inner chamber of the sliding sleeve is slidably connected with a sliding rod, and the two sides of the sliding rod are fixedly connected with the shell.

[0010] Preferably, the front of the connecting pipe is movably connected with a control valve, and the left side of the discharge pipe is movably connected with an adjusting valve.

[0011] Preferably, the left side of the top of the work table is fixedly connected with a supporting column, and the top of the supporting column is fixedly connected with the horizontal plate.

[0012] Preferably, the right side of the hollow block is provided with a through hole, and the top of the hollow block is provided with a rectangular groove, and the inner chamber of the rectangular groove is slidably connected with the connecting frame.

[0013] Compared with the prior art, the utility model has the beneficial effects that:

[0014] 1. By setting the collection detection mechanism, through endoscopic technology, through the oral cavity insertion puncture needle, then along the puncture needle insertion confocal probe, through the confocal probe to identify the lesion location, then pull the optical fiber, so as to take out the confocal probe, then the puncture needle and the gooseneck pipe are inserted, the puncture needle enters the lesion tissue, and the electric telescopic rod is started, the electric telescopic rod drives the connecting frame to move, the connecting frame drives the sealing plate to move, so as to carry out the negative pressure suction work, so as to suck the cells into the hollow block inner cavity, after sucking part of the cells, the electric telescopic rod can be controlled to shrink, so as to push the cells into the fixed tube inner cavity through the sealing plate, the cells are discharged to the top of the bearing plate through the fixed tube, then the electric telescopic rod is controlled to stretch again, and the cells are subjected to negative pressure suction, so that the collection work is facilitated, and the bearing plate is moved to the detection position, and the detection work is carried out through the detection probe.

[0015] 2. By setting the cleaning mechanism, after the work is completed, the gooseneck pipe is inserted with the box body, the electric telescopic rod is started again, the electric telescopic rod reciprocatingly stretches and shrinks, so that the sealing plate vertically reciprocates, the cleaning liquid in the box cavity is sucked into the hollow block inner cavity through the gooseneck pipe during the ascending process of the sealing plate, and the cleaning liquid is discharged during the descending process, so that the cleaning effect is achieved, and the bearing plate is moved to the bottom of the spray head, the pump is started, the cleaning liquid in the box cavity is pumped out, and the cleaning liquid is sprayed to the top of the bearing plate through the discharge pipe and the spray head, so that the flushing work is carried out. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 It is a structural schematic view of the utility model;

[0017] Figure 2 It is a three-dimensional structural schematic view of the utility model;

[0018] Figure 3 It is a local three-dimensional structural schematic view of the collection detection mechanism of the utility model;

[0019] Figure 4 It is a hollow block cross-sectional structural schematic view of the utility model;

[0020] Figure 5 It is a puncture needle structural schematic view of the utility model;

[0021] Figure 6 It is a puncture needle cross-sectional structural schematic view of the utility model.

[0022] In the figure: 1, workbench; 2, collection detection mechanism; 201, cross plate; 202, hollow block; 203, electric telescopic rod; 204, connecting frame; 205, sealing plate; 206, through hole; 207, first one-way valve; 208, swan neck pipe; 209, shell; 210, toothed plate; 211, gear; 212, motor; 213, sliding sleeve; 214, sliding rod; 215, fixing frame; 216, bearing plate; 217, detection probe; 218, second one-way valve; 219, fixed pipe; 220, puncture needle; 221, confocal probe; 222, optical fiber; 3, cleaning mechanism; 301, box; 302, connecting pipe; 303, pump; 304, discharge pipe; 305, spray head; 306, collection frame; 4, support column. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all the other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.

[0024] Please refer to Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 and Figure 6The utility model provides a technical scheme: a device that can carry out tissue cell collection and confocal imaging simultaneously, which comprises a workbench 1, a collection and detection mechanism 2 arranged on one side of the workbench 1, the collection and detection mechanism 2 comprising a horizontal plate 201, the horizontal plate 201 being fixedly connected with a hollow block 202 on one side, the hollow block 202 being fixedly connected with an electric telescopic rod 203 on the front side, the electric telescopic rod 203 being fixedly connected with a connecting frame 204 on one side, the connecting frame 204 being fixedly connected with a sealing plate 205 on one side, the left side of the bottom of the hollow block 202 being communicated with a first check valve 207, the first check valve 207 being communicated with a goose neck pipe 208 on one side, the right side of the bottom of the hollow block 202 being communicated with a second check valve 218, the second check valve 218 being communicated with a fixed tube 219 on one side, the right side of the top of the workbench 1 being fixedly connected with a detection probe 217, the detection probe 217 being provided with a bearing plate 216 on one side, the inner cavity of a puncture needle 220 being provided with a confocal probe 221, the confocal probe 221 being fixedly connected with an optical fiber 222 on one side, the collection and detection mechanism 2 being arranged, the puncture needle 220 being inserted into the mouth through endoscopic technology, then the confocal probe 221 is inserted along the puncture needle 220, the lesion position is identified through the confocal probe 221, then the optical fiber 222 is pulled, so that the confocal probe 221 is taken out, then the puncture needle 220 is inserted into the goose neck pipe 208, after the puncture needle 220 enters the lesion tissue, the electric telescopic rod 203 is started, the electric telescopic rod 203 drives the connecting frame 204 to move, the connecting frame 204 drives the sealing plate 205 to move, so that negative pressure suction work is carried out, so that the cells are sucked into the inner cavity of the hollow block 202, after part of the cells are sucked, the electric telescopic rod 203 can be controlled to contract, so that the cells are pushed into the inner cavity of the fixed tube 219 through the sealing plate 205, the cells are discharged to the top of the bearing plate 216 through the fixed tube 219, then the electric telescopic rod 203 is controlled to stretch again, the cells are subjected to negative pressure suction, so that the collection work is facilitated, at the same time, the bearing plate 216 is moved to a detection position, detection work is carried out through the detection probe 217.The front side of the bottom of the workbench 1 is fixedly connected with a shell 209, the front side of the inner cavity of the shell 209 is fixedly connected with a toothed plate 210, one side of the toothed plate 210 is engaged with a gear 211, one side of the gear 211 is fixedly connected with a motor 212, one side of the motor 212 is fixedly connected with a sliding sleeve 213, one side of the sliding sleeve 213 is fixedly connected with a fixing frame 215, one side of the fixing frame 215 is fixedly connected with a bearing plate 216, the motor 212 is started, the gear 211 is driven to rotate by the motor 212, the gear 211 is also moved in the rotating process through the cooperation of the toothed plate 210, that is, the motor 212 can be driven to move, the motor 212 drives the sliding sleeve 213 to move, the sliding sleeve 213 drives the fixing frame 215 to move, and the fixing frame 215 drives the bearing plate 216 to move, so that the position of the bearing plate 216 is conveniently adjusted, the inner cavity of the sliding sleeve 213 is slidably connected with a sliding rod 214, the two sides of the sliding rod 214 are fixedly connected with the shell 209, the sliding rod 214 is arranged, the work of the sliding sleeve 213 is stabilized, and therefore the motor 212 is stable during work; the left side of the top of the workbench 1 is fixedly connected with a supporting column 4, the top of the supporting column 4 is fixedly connected with the horizontal plate 201, the supporting column 4 is arranged, the work of the horizontal plate 201 is stabilized, and the horizontal plate 201 is supported; the right side of the hollow block 202 is provided with a through hole 206, the top of the hollow block 202 is provided with a rectangular groove, and the inner cavity of the rectangular groove is slidably connected with the connecting frame 204, the rectangular groove is arranged, the work of the connecting frame 204 is stabilized, and the connecting frame 204 is balanced and supported.

[0025] See Figure 1 and Figure 2The other side of the workbench 1 is provided with a cleaning mechanism 3, the cleaning mechanism 3 includes a box body 301, the bottom of the box body 301 is fixedly connected with the horizontal plate 201, a connecting pipe 302 is communicated with the right side of the bottom of the box body 301, a pump machine 303 is communicated with the left side of the bottom of the box body 301, a discharge pipe 304 is communicated with one side of the pump machine 303, a spray head 305 is communicated with one side of the discharge pipe 304, a collecting frame 306 is fixedly connected with the middle shaft of the top of the workbench 1, by arranging the cleaning mechanism 3, after the work is completed, the gooseneck pipe 208 is inserted with the box body 301, the electric telescopic rod 203 is started again, so that the electric telescopic rod 203 reciprocatingly stretches and shrinks, the sealing plate 205 can vertically reciprocate, the cleaning liquid in the inner cavity of the box body 301 is sucked into the inner cavity of the hollow block 202 through the gooseneck pipe 208 in the lifting process of the sealing plate 205, and the cleaning liquid is discharged in the descending process, so that the cleaning effect is achieved, and the bearing plate 216 is moved to the bottom of the spray head 305, the pump machine 303 is started, the cleaning liquid in the inner cavity of the box body 301 is pumped out, and the cleaning liquid is sprayed to the top of the bearing plate 216 through the discharge pipe 304 and the spray head 305, so that the flushing work is carried out; the front of the connecting pipe 302 is movably connected with a control valve, and the left side of the discharge pipe 304 is movably connected with an adjusting valve, by arranging the control valve, the cleaning liquid can be conveniently discharged into the inner cavity of the gooseneck pipe 208 through the connecting pipe 302, so that the cleaning work is facilitated.

[0026] Working principle: by arranging the collection detection mechanism 2, by endoscopic technology, the puncture needle 220 is inserted into the oral cavity, then the confocal probe 221 is inserted along the puncture needle 220, the lesion position is identified through the confocal probe 221, then the optical fiber 222 is pulled, so that the confocal probe 221 is taken out, then the puncture needle 220 is inserted with the gooseneck pipe 208, after the puncture needle 220 enters the lesion tissue, the electric telescopic rod 203 is started, the electric telescopic rod 203 drives the connecting frame 204 to move, the connecting frame 204 drives the sealing plate 205 to move, so that the negative pressure suction work is carried out, so that the cells are sucked into the inner cavity of the hollow block 202, after part of the cells are sucked, the electric telescopic rod 203 can be controlled to contract, so that the cells are pushed into the inner cavity of the fixed pipe 219 through the sealing plate 205, the cells are discharged to the top of the bearing plate 216 through the fixed pipe 219, then the electric telescopic rod 203 is controlled to stretch again, the cells are subjected to negative pressure suction, so that the collection work is facilitated, and the bearing plate 216 is moved to the detection position, the detection work is carried out through the detection probe 217;

[0027] By setting the cleaning mechanism 3, after the work is completed, the gooseneck pipe 208 is inserted with the box body 301, and the electric telescopic rod 203 is started again, so that the electric telescopic rod 203 reciprocatingly extends and retracts, so that the sealing plate 205 vertically reciprocates, and in the ascending process of the sealing plate 205, the cleaning liquid in the inner cavity of the box body 301 is sucked into the inner cavity of the hollow block 202 through the gooseneck pipe 208, and in the descending process, the cleaning liquid is discharged, so as to achieve the cleaning effect, and the bearing plate 216 is moved to the bottom of the nozzle 305, the pump 303 is started, the cleaning liquid in the inner cavity of the box body 301 is pumped out, and the cleaning liquid is sprayed to the top of the bearing plate 216 through the discharge pipe 304 and the nozzle 305, so as to perform the flushing work.

[0028] Although the embodiments of the present application have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and modifications can be made to these embodiments without departing from the principles and spirits of the present application, and the scope of the present application is defined by the appended claims and their equivalents.

Claims

1. A device capable of simultaneously performing tissue cell collection and confocal imaging, characterized in that: The device includes a workbench (1) and a puncture needle (220). A collection and detection mechanism (2) is provided on one side of the workbench (1). The collection and detection mechanism (2) includes a horizontal plate (201). A hollow block (202) is fixedly connected to one side of the horizontal plate (201). An electric telescopic rod (203) is fixedly connected to the front of the hollow block (202). A connecting frame (204) is fixedly connected to one side of the electric telescopic rod (203). A sealing plate (205) is fixedly connected to one side of the connecting frame (204). A first one-way valve is connected to the left side of the bottom of the hollow block (202). (207), a gooseneck tube (208) is connected to one side of the first one-way valve (207), a second one-way valve (218) is connected to the right side of the bottom of the hollow block (202), a fixed tube (219) is connected to one side of the second one-way valve (218), a detection probe (217) is fixedly connected to the right side of the top of the workbench (1), a support plate (216) is provided on one side of the detection probe (217), a confocal probe (221) is provided in the inner cavity of the puncture needle (220), and an optical fiber (222) is fixedly connected to one side of the confocal probe (221).

2. The device for simultaneously performing tissue cell collection and confocal imaging according to claim 1, characterized in that: A cleaning mechanism (3) is provided on the other side of the workbench (1). The cleaning mechanism (3) includes a box (301). The bottom of the box (301) is fixedly connected to the horizontal plate (201). A connecting pipe (302) is connected to the right side of the bottom of the box (301). A pump (303) is connected to the left side of the bottom of the box (301). A discharge pipe (304) is connected to one side of the pump (303). A nozzle (305) is connected to one side of the discharge pipe (304). A collection frame (306) is fixedly connected to the central axis at the top of the workbench (1).

3. The device for simultaneously performing tissue cell collection and confocal imaging according to claim 1, characterized in that: A housing (209) is fixedly connected to the front side of the bottom of the workbench (1). A toothed plate (210) is fixedly connected to the front side of the inner cavity of the housing (209). A gear (211) meshes with one side of the toothed plate (210). A motor (212) is fixedly connected to one side of the gear (211). A sliding sleeve (213) is fixedly connected to one side of the motor (212). A fixing frame (215) is fixedly connected to one side of the sliding sleeve (213). A bearing plate (216) is fixedly connected to one side of the fixing frame (215).

4. The device for simultaneously performing tissue cell collection and confocal imaging according to claim 3, characterized in that: The inner cavity of the sliding sleeve (213) is slidably connected to a sliding rod (214), and both sides of the sliding rod (214) are fixedly connected to the housing (209).

5. The device for simultaneously performing tissue cell collection and confocal imaging according to claim 2, characterized in that: A control valve is movably connected to the front of the connecting pipe (302), and an adjusting valve is movably connected to the left side of the discharge pipe (304).

6. The device for simultaneously performing tissue cell collection and confocal imaging according to claim 1, characterized in that: A support column (4) is fixedly connected to the left side of the top of the workbench (1), and the top of the support column (4) is fixedly connected to the horizontal plate (201).

7. The device for simultaneously performing tissue cell collection and confocal imaging according to claim 1, characterized in that: The hollow block (202) has a through hole (206) on its right side and a rectangular groove on its top, with the inner cavity of the rectangular groove slidably connected to the connecting frame (204).

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