Spray drying device for preparing enrofloxacin water emulsion particles

Abstract

The spray drying device comprises a bottom plate, the middle side of the upper end of the bottom plate is connected with a machine body, the lower side of the interior of the machine body is connected with a hot air pipe, and the lower side of the machine body is connected with a discharging pipe; an atomizer is arranged on the middle side of the upper end of the machine body, a stirring structure is connected to the middle side in the machine body, and the stirring structure comprises a connecting plate, a motor and a connecting wheel; and the connecting pipe is mounted on the outer side of the hot air pipe, the upper side of the connecting pipe is connected with a mounting plate, the outer side of the upper end of the mounting plate is connected with a flow guide plate, a scraping structure is mounted on the outer side of the mounting plate, and the scraping structure comprises a scraping plate and a fixing plate. According to the spray drying device for preparing the enrofloxacin water emulsion particles, the stirring structure is arranged, mass transfer can be promoted, the material uniformity can be guaranteed, and therefore the drying effect of enrofloxacin water emulsion is improved, and the scraping structure is arranged, so that the inner wall of the drying device can be cleaned.

Description

Technical Field

[0001] This utility model relates to the field of enrofloxacin water-emulsion particle preparation technology, specifically a spray drying device for preparing enrofloxacin water-emulsion particles. Background Technology

[0002] Enrofloxacin emulsion is a liquid formulation in which enrofloxacin is dispersed in an oil-in-water or water-in-oil manner. It is a homogeneous emulsion formed by dispersing enrofloxacin (usually oil-soluble) in an aqueous phase through emulsification technology. It appears milky white or semi-transparent. Spray drying equipment is required in the preparation of enrofloxacin emulsion granules to quickly dry and form granules while maintaining drug activity.

[0003] Based on existing solutions and actual production and processing applications, the current spray drying equipment for preparing enrofloxacin water-emulsion granules still has some problems, such as:

[0004] 1. Existing spray drying equipment spray-dries enrofloxacin emulsion by atomizing the enrofloxacin emulsion and then drying it with hot air. However, the drying effect of using hot air on enrofloxacin emulsion is limited, which leads to poor particle formation of enrofloxacin emulsion.

[0005] 2. Existing spray drying devices require operators to manually clean the inner walls of the drying device using a hand-held cleaning brush, which is time-consuming and labor-intensive. Therefore, this utility model provides a spray drying device for preparing enrofloxacin water-emulsion granules to solve the above-mentioned problems. Utility Model Content

[0006] The purpose of this invention is to provide a spray drying device for preparing enrofloxacin emulsion particles, in order to solve the problems mentioned in the background art. In the existing spray drying devices, enrofloxacin emulsion is atomized and then dried with hot air. However, the drying effect of hot air on enrofloxacin emulsion is limited, resulting in poor particle formation. In the existing spray drying devices, the inner wall of the device needs to be cleaned by the operator holding a cleaning brush, which is time-consuming and laborious.

[0007] To achieve the above objectives, the present invention provides the following technical solution: a spray drying device for preparing enrofloxacin water-emulsion granules, comprising a base plate, an organic body connected to the middle of its upper end, a hot air pipe connected to the lower side of the interior of the machine body, and a discharge pipe connected to the lower side of the machine body;

[0008] Also includes:

[0009] An atomizer is provided on the upper middle side of the body, and a flow divider is connected to the lower side of the atomizer. A stirring structure is connected to the inner middle side of the body, and the stirring structure includes a connecting plate, a motor and a connecting wheel. The connecting plate is installed on the inner middle side of the body, and a motor is provided on the lower side of the connecting plate. The output end of the motor is connected to the connecting wheel.

[0010] A connecting pipe is installed on the outside of the hot air duct, and an installation plate is connected to the upper side of the connecting pipe. A guide plate is connected to the outer side of the upper end of the installation plate, and a scraping structure is installed on the outer side of the installation plate. The scraping structure includes a scraper and a fixing plate, and the fixing plate is installed on the outer side of the installation plate, and a scraper is connected to the outer side of the fixing plate.

[0011] Preferably, a baffle plate is movably connected to the upper right side of the body, and the baffle plate is engaged with the body.

[0012] Preferably, a material cylinder is provided on the upper left side of the machine body, and a pump body is provided on the right side of the material cylinder, and the pump body is connected to the atomizer through a flow tube.

[0013] Preferably, the hot air duct and the connecting pipe are rotatably connected, and the connecting pipe and the connecting wheel are meshing connected.

[0014] Preferably, the guide plate and the mounting plate are fixedly connected by welding, and the guide plate is provided with a nozzle at its outer end.

[0015] Preferably, the scraper and the fixing plate are interlocked, the vertical cross-section of the fixing plate is an "L" shape, and a support block is fixedly installed on the lower outer side of the fixing plate.

[0016] Preferably, a fixing rod is also connected to the upper side of the scraper, and the fixing rod and the scraper are connected by a thread.

[0017] Compared with the prior art, the beneficial effects of this utility model are: the spray drying device for preparing enrofloxacin water-emulsion particles is equipped with a stirring structure, which can promote mass transfer and ensure material uniformity, thereby improving the drying effect of enrofloxacin water-emulsion; and it is also equipped with a scraping structure, which can clean the inner wall of the drying device.

[0018] 1. By starting the pump, the enrofloxacin emulsion inside the barrel is drawn into the atomizer for atomization. The atomized enrofloxacin emulsion then enters the distributor plate and is sprayed out. Hot air then enters the mounting plate through the hot air pipe. The hot air passes through the mounting plate and enters the guide plate before being sprayed out. Starting the motor drives the connecting wheel to rotate, which in turn drives the mounting plate to rotate through the connecting pipe meshing with the connecting wheel. This, in turn, drives the guide plate to rotate, which in turn stirs the hot air and the atomized enrofloxacin emulsion, ensuring a good drying effect for the enrofloxacin emulsion.

[0019] 2. By pulling the baffle plate, the baffle plate is separated on the upper right side of the machine body, so that the fixed plate can be cleaned. Then, the scraper is installed on the outside of the fixed plate through the opening on the right side of the machine body. Rotate the fixing rod so that the fixing rod is threaded on the upper side of the scraper, so that the fixing rod moves downward and is threaded on the upper side of the fixed plate, which facilitates the limiting of the scraper.

[0020] 3. By starting the motor, the motor drives the connecting wheel to rotate on the left side of the connecting plate, which in turn drives the connecting pipe that meshes with the connecting wheel to rotate the mounting plate on the upper side of the hot air pipe. This causes the mounting plate to rotate the fixing plate, which in turn causes the scraper to rotate inside the machine body. This allows the scraper to clean the inner wall of the machine body, making it easier to clean the inner wall of the machine body. Attached Figure Description

[0021] Figure 1 This is a schematic cross-sectional view of the connection between the base plate and the body of this utility model.

[0022] Figure 2 This utility model Figure 1 Enlarged structural diagram at point A in the middle;

[0023] Figure 3 This utility model Figure 1 Enlarged structural diagram at point B;

[0024] Figure 4 This is a schematic cross-sectional view of the connection between the body and the connecting plate of this utility model.

[0025] Figure 5 This utility model Figure 4 Enlarged structural diagram at point C;

[0026] Figure 6 This is an exploded structural diagram of the connection between the mounting plate and the support block of this utility model.

[0027] In the diagram: 1. Base plate; 2. Machine body; 3. Discharge pipe; 4. Material cylinder; 5. Pump body; 6. Atomizer; 7. Diverter plate; 8. Baffle plate; 9. Hot air pipe; 10. Mounting plate; 11. Support block; 12. Guide plate; 13. Scraper; 14. Fixing plate; 15. Connecting plate; 16. Motor; 17. Connecting wheel; 18. Connecting pipe; 19. Fixing rod. Detailed Implementation

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0029] Please see Figure 1-6 This utility model provides a technical solution: a spray drying device for preparing enrofloxacin water-based emulsion granules, comprising: a base plate 1, a machine body 2, a discharge pipe 3, a material cylinder 4, a pump body 5, an atomizer 6, a flow divider 7, a baffle plate 8, a hot air pipe 9, a mounting plate 10, a support block 11, a guide plate 12, a scraper 13, a fixing plate 14, a connecting plate 15, a motor 16, a connecting wheel 17, a connecting pipe 18, and a fixing rod 19. In operation, the specific details are as follows... Figure 1 , Figure 2 , Figure 4 , Figure 5 and Figure 6 As shown, the machine body 2 is fixedly installed on the upper middle side of the base plate 1. The material cylinder 4 is fixedly installed on the upper left side of the machine body 2. The pump body 5 is installed on the right side of the material cylinder 4. The atomizer 6 is installed on the right side of the pump body 5. The flow divider plate 7 is connected to the lower right side of the atomizer 6. Hot air is delivered to the inside of the hot air pipe 9 by a hot air blower. The hot air inside the hot air pipe 9 enters the inside of the mounting plate 10 through the connecting pipe 18. The hot air then enters the inside of the guide plate 12 through the mounting plate 10. The hot air is then sprayed out through the nozzle on the outside of the guide plate 12. The pump body 5 is then started, which draws the material inside the material cylinder 4 into the atomizer 6 for atomization. The atomized material then enters the inside of the flow divider plate 7. The atomized material is then sprayed out through the nozzle on the lower side of the flow divider plate 7 into the inside of the machine body 2. The pump body 5 is then started. The motor 16 installed on the lower side of the connecting plate 15 drives the connecting wheel 17 connected to the output end of the motor 16 to rotate on the left side of the connecting plate 15. The rotation of the connecting wheel 17 causes the connecting wheel 17 to mesh with the connecting pipe 18. The meshing action between the connecting wheel 17 and the connecting pipe 18 causes the connecting pipe 18 to drive the mounting plate 10 to rotate, which in turn causes the mounting plate 10 to drive the fixing plate 14 to rotate. This causes the mounting plate 10 to drive the guide plate 12 to rotate, which in turn causes the guide plate 12 to stir the atomized material sprayed inside the machine body 2. The guide plate 12 then sprays hot air to dry the atomized material inside the machine body 2, ensuring the drying effect of the enrofloxacin water emulsion. The dried enrofloxacin water emulsion is discharged through the discharge pipe 3.

[0030] Specific examples Figure 1 and Figure 3As shown, a baffle plate 8 is provided on the upper right side of the machine body 2, and a scraper 13 is movably installed on the outside of the fixed plate 14. A fixed rod 19 is connected to the upper end of the scraper 13. By manually pulling the baffle plate 8 upward, the baffle plate 8 moves upward under the pulling force, thereby separating the baffle plate 8 on the upper right side of the machine body 2. This allows the fixed plate 14 to be cleaned using tools. Then, the scraper 13 is placed inside the machine body 2 through the perforated structure on the upper right side of the machine body 2, so that the scraper 13 moves inside the machine body 2 under the placement action. The outer side of the fixing plate 14 moves downward, so that the scraper 13 is engaged and installed on the outer side of the fixing plate 14 under the action of the scraper 13 moving downward. Then, the fixing rod 19 installed on the upper side of the scraper 13 is screwed, so that the fixing rod 19 is threaded on the upper side of the scraper 13 under the action of screwing. Thus, the fixing rod 19 moves downward under the action of the thread between the fixing rod 19 and the scraper 13, and then the fixing rod 19 is threaded on the upper side of the fixing plate 14 under the action of the downward movement of the fixing rod 19, which facilitates the installation and limiting of the scraper 13.

[0031] Specific examples Figure 1 , Figure 2 , Figure 3 and Figure 5 As shown, a connecting plate 15 is fixedly installed on the lower side of the inside of the machine body 2. A motor 16 is fixedly installed on the left side of the lower end of the connecting plate 15. A connecting wheel 17 is connected to the output end of the motor 16. A connecting pipe 18 is movably connected to the left end of the connecting wheel 17. When the motor 16 is started, the connecting wheel 17 rotates on the left side of the connecting plate 15 under the driving action of the motor 16. As a result, the connecting pipe 18, which is meshed with the connecting wheel 17, rotates on the upper side of the hot air pipe 9. This causes the connecting pipe 18 to drive the mounting plate 10 to rotate. As a result, the mounting plate 10 drives the fixing plate 14 to rotate. As a result, the fixing plate 14 drives the scraper 13 to rotate. As a result, the fixing plate 14 drives the support block 11 to rotate. As a result, the scraper 13 scrapes the inner wall of the machine body 2, making it convenient to clean the inner wall of the machine body 2.

[0032] All standard parts used in this utility model can be purchased from the market, and irregular parts can be customized according to the description and drawings. The specific connection methods of each part adopt conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment adopt conventional models in the prior art. In addition, the circuit connection adopts conventional connection methods in the prior art, which will not be described in detail here. The contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0033] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A spray drying device for preparing enrofloxacin water-emulsion granules, comprising a base plate (1), an organic body (2) connected to the middle of its upper end, a hot air pipe (9) connected to the lower side of the interior of the organic body (2), and a discharge pipe (3) connected to the lower side of the organic body (2). Its features are, Also includes: An atomizer (6) is provided on the upper middle side of the body (2), and a flow divider (7) is connected to the lower side of the atomizer (6). A stirring structure is connected to the inner middle side of the body (2), and the stirring structure includes a connecting plate (15), a motor (16) and a connecting wheel (17). The connecting plate (15) is installed on the inner middle side of the body (2), and a motor (16) is provided on the lower side of the connecting plate (15). The output end of the motor (16) is connected to the connecting wheel (17). A connecting pipe (18) is installed on the outside of the hot air pipe (9), and an mounting plate (10) is connected to the upper side of the connecting pipe (18). A guide plate (12) is connected to the upper outer side of the mounting plate (10), and a scraping structure is installed on the outside of the mounting plate (10). The scraping structure includes a scraper (13) and a fixing plate (14). The fixing plate (14) is installed on the outside of the mounting plate (10), and the scraper (13) is connected to the outside of the fixing plate (14).

2. The spray drying apparatus for preparing enrofloxacin water-emulsion particles according to claim 1, characterized in that: A baffle plate (8) is movably connected to the upper right side of the body (2), and the baffle plate (8) and the body (2) are connected by a snap-fit ​​connection.

3. The spray drying apparatus for preparing enrofloxacin water-emulsion particles according to claim 2, characterized in that: The upper left side of the body (2) is provided with a material cylinder (4), and the right side of the material cylinder (4) is provided with a pump body (5), and the pump body (5) is connected to the atomizer (6) through a flow tube.

4. The spray drying apparatus for preparing enrofloxacin water-emulsion particles according to claim 1, characterized in that: The hot air pipe (9) and the connecting pipe (18) are rotatably connected, and the connecting pipe (18) and the connecting wheel (17) are meshing connected.

5. The spray drying apparatus for preparing enrofloxacin water-emulsion particles according to claim 1, characterized in that: The guide plate (12) and the mounting plate (10) are fixedly connected by welding, and the guide plate (12) is provided with a nozzle on its outer side.

6. The spray drying apparatus for preparing enrofloxacin water-emulsion particles according to claim 1, characterized in that: The scraper (13) and the fixing plate (14) are connected by a snap-fit ​​connection, and the vertical cross-section of the fixing plate (14) is an "L" shaped structure. A support block (11) is also fixedly installed on the lower outer side of the fixing plate (14).

7. The spray drying apparatus for preparing enrofloxacin water-emulsion particles according to claim 6, characterized in that: A fixing rod (19) is also connected to the upper side of the scraper (13), and the fixing rod (19) and the scraper (13) are connected by a thread.

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