Mixed reaction device
By employing a combination of a motor-driven stirring shaft and inclined stirring blades with an electric push rod and a vertical pipe in the mixing reaction equipment, the problem of uneven mixing was solved, achieving uniform mixing and efficient stirring in an aerobic environment, thus improving product quality.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- YINGBAIRUI (HANGZHOU) MEDICAL RESEARCH CO LTD
- Filing Date
- 2025-02-27
- Publication Date
- 2026-04-14
AI Technical Summary
Existing mixing and reaction equipment uses a single stirring method, resulting in uneven mixing, especially with significant differences in mixing effect in different areas of the reactor, which affects product quality.
An axial flow is formed by a motor-driven stirring shaft and inclined stirring blades, which, combined with the radial flow of an electric push rod and a vertical pipe, forms a combined stirring method through an air inlet pipe and a one-way valve to supplement air and provide an aerobic environment.
This achieves more uniform mixing, avoids differences in mixing effects, improves product quality, and enables effective stirring in an aerobic environment.
Smart Images
Figure CN224118987U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of biopharmaceutical technology, and in particular to a mixing reaction apparatus. Background Technology
[0002] In biopharmaceuticals, mixing equipment plays a crucial role. It is primarily responsible for ensuring the uniform mixing of reactants during biopharmaceutical production, thereby improving production efficiency and product quality. The external container of the mixing reaction is the main body of the bioreactor, used to contain the organisms, culture medium, and the conditions required for the reaction, while the stirrer is used to maintain the uniform suspension of the culture medium and promote sufficient contact between the organisms and the culture medium.
[0003] In existing technologies, the stirring blades in mixing reaction equipment generally produce axial or radial flow when rotating, which cannot form a combination. The stirring method is singular, which may lead to uneven mixing, especially in different areas of the reactor, where the mixing effect may vary greatly, which will affect product quality. Therefore, we propose a mixing reaction device to solve the above problems. Utility Model Content
[0004] The purpose of this invention is to address the shortcomings of existing technologies by proposing a mixed reaction device.
[0005] To achieve the above objectives, the present invention adopts the following technical solution:
[0006] A mixing reaction device includes a tank, a base frame fixedly connected to the bottom of the tank, a motor fixedly connected inside the base frame, a stirring shaft fixedly connected to the top of the motor output shaft, multiple inclined stirring blades fixedly connected to the outer wall of the stirring shaft, a frame fixedly connected to the top of the tank, an electric push rod fixedly connected inside the frame, a vertical pipe fixedly connected inside the tank, a fixed pipe fixedly connected to the bottom of the output end of the electric push rod, two air holes opened on the outer wall of the fixed pipe, a through hole opened on the outer wall of the tank, an air inlet pipe fixedly connected to the inner wall of the through hole, one end of the air inlet pipe being fixedly interconnected with the outer wall of the vertical pipe, and a mixing mechanism provided inside the tank.
[0007] Preferably, the mixing mechanism includes a hollow piston, and one-way valves are fixedly installed on the outer walls of both the air inlet pipe and the fixed pipe. The bottom of the fixed pipe is fixedly connected to the top of the piston, and the liquid biological raw materials are stirred and mixed by setting the mixing mechanism.
[0008] Preferably, the top of the tank is fixedly connected to an injection pipe for adding liquid biological raw materials, and a pressure relief valve is fixedly installed on the top of the tank.
[0009] Preferably, the bottom of the tank is provided with a through hole, and the inner wall of the through hole is rotatably connected to the outer wall of the motor output shaft. By setting the motor to drive the inclined stirring blades to rotate, axial flow stirring is formed.
[0010] Preferably, the vertical pipe and the top of the tank have the same through hole, the inner wall of the through hole is slidably connected to the outer wall of the output end of the electric push rod, and sealing gaskets are installed on the inner walls of the through hole and the through hole.
[0011] Preferably, the outer wall of the piston is slidably connected to the inner wall of the vertical tube.
[0012] Preferably, the outer wall of the tank is fixedly fitted with a shell, and multiple electric heating plates are fixedly connected inside the shell.
[0013] Compared with the prior art, the advantages of this utility model are:
[0014] This solution combines radial and axial flow by incorporating a motor, stirring shaft, inclined stirring blades, frame, electric push rod, vertical pipe, fixed pipe, air inlet pipe, one-way valve, air hole, and piston. This avoids significant differences in mixing effect and allows for timely air replenishment in aerobic reaction environments. Attached Figure Description
[0015] To more clearly illustrate the technical solution of this utility model, the drawings used in the description of the specific embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0016] Figure 1 This is a three-dimensional structural diagram of a mixing reaction device proposed in this utility model;
[0017] Figure 2 This is a cross-sectional structural diagram of a mixing reaction device proposed in this utility model;
[0018] Figure 3 This is a partial cross-sectional three-dimensional structural diagram of a mixing reaction device proposed in this utility model;
[0019] Figure 4 This invention proposes a mixing reaction device. Figure 2 A magnified structural diagram of part A in the diagram.
[0020] In the diagram: 1. Tank body; 2. Injection pipe; 3. Seat frame; 4. Motor; 5. Agitator shaft; 6. Inclined agitator blade; 7. Frame; 8. Electric push rod; 9. Vertical pipe; 10. Fixed pipe; 11. Air inlet pipe; 12. One-way valve; 13. Air hole; 14. Piston; 15. Shell. Detailed Implementation
[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.
[0022] Depend on Figures 1-4 As shown, a mixing reaction device is disclosed, comprising a tank 1, a feeding pipe 2 fixedly connected to the top of the tank 1, a base frame 3 fixedly connected to the bottom of the tank 1, a motor 4 fixedly connected inside the base frame 3, a through hole opened at the bottom of the tank 1, the inner wall of the through hole being rotatably connected to the outer wall of the output shaft of the motor 4, a stirring shaft 5 fixedly connected to the top of the output shaft of the motor 4, and multiple inclined stirring blades 6 fixedly connected to the outer wall of the stirring shaft 5. The operation of the motor 4 drives the stirring shaft 5 to rotate, and the rotation of the stirring shaft 5 drives the inclined stirring blades 6 to rotate, thereby mixing the liquid in an axial flow.
[0023] A frame 7 is fixedly connected to the top of the tank 1. An electric push rod 8 is fixedly connected inside the frame 7. The frame 7 protects the electric push rod 8. A vertical pipe 9 is fixedly connected inside the tank 1. The vertical pipe 9 and the top of the tank 1 have the same through hole. The inner wall of the through hole is slidably connected to the outer wall of the output end of the electric push rod 8.
[0024] A fixed tube 10 is fixedly connected to the bottom of the output end of the electric push rod 8. Two air holes 13 are opened on the outer wall of the fixed tube 10. A through hole is opened on the outer wall of the tank body 1. An air inlet pipe 11 is fixedly connected to the inner wall of the through hole. One end of the air inlet pipe 11 is fixedly connected to the outer wall of the vertical pipe 9, and the other end of the air inlet pipe 11 is fixedly connected to the existing air sterilizer.
[0025] The tank 1 is equipped with a mixing mechanism, which includes a hollow piston 14. The outer wall of the piston 14 is slidably connected to the inner wall of the vertical pipe 9. The piston 14 moves up and down through the vertical pipe 9 to draw the liquid in the tank 1 into the vertical pipe 9 and then discharge it, forming a radial flow stirring. The outer wall of the tank 1 is fixedly fitted with a shell 15. Multiple electric heating plates are fixedly connected inside the shell 15. One-way valves 12 are fixedly installed on the outer walls of the air inlet pipe 11 and the fixed pipe 10. The one-way valves 12 draw sterile air from the outside into the vertical pipe 9. As the piston 14 moves upward, the air is compressed and discharged through the fixed pipe 10. The bottom of the fixed pipe 10 is fixedly connected to the top of the piston 14.
[0026] Working principle: During use, liquid biological raw materials enter the tank 1 through the injection pipe 2. During the mixing reaction, the motor 4 drives the stirring shaft 5 to rotate, which in turn drives the inclined stirring blades 6 to rotate, mixing the liquid. At the same time, the electric push rod 8 drives the vertical pipe 9 and the fixed pipe 10 to move up and down reciprocally. The up and down movement of the fixed pipe 10 drives the piston 14 to move up and down. When the piston 14 moves up and down in the vertical pipe 9, sterile air enters the vertical pipe 9 through the air inlet pipe 11 and is located in the cavity between the piston 14 and the vertical pipe 9. Due to the one-way action of the one-way valve 12, the air cannot be discharged in reverse and enters the fixed pipe 10 through the two air holes 13. It is then discharged through the piston 14, providing an aerobic environment for the biological reaction. At the same time, when the piston 14 moves back and forth, it repeatedly draws the liquid in the tank 1 into the interior of the vertical pipe 9 through suction, and then discharges it through the pushing force of the piston 14. Air enters the tank 1 along with the liquid, achieving a better stirring effect.
[0027] All standard parts used in this utility model can be purchased from the market. Irregular parts can be customized according to the description and drawings. The specific connection methods of each part adopt conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment adopt conventional models in the prior art. In addition, the circuit connection adopts conventional connection methods in the prior art, which will not be described in detail here. Furthermore, the structure and principle of the components known to those skilled in the art can be learned by those skilled in the art through technical manuals or conventional experimental methods.
[0028] Although embodiments of this application have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of this application, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A mixing reaction apparatus, comprising a tank (1), characterized in that, The bottom of the tank (1) is fixedly connected to a seat frame (3), the inside of the seat frame (3) is fixedly connected to a motor (4), the top of the output shaft of the motor (4) is fixedly connected to a stirring shaft (5), the outer wall of the stirring shaft (5) is fixedly connected to multiple inclined stirring blades (6), the top of the tank (1) is fixedly connected to a frame (7), the inside of the frame (7) is fixedly connected to an electric push rod (8), the inside of the tank (1) is fixedly connected to a vertical pipe (9), the bottom of the output end of the electric push rod (8) is fixedly connected to a fixed pipe (10), the outer wall of the fixed pipe (10) has two air holes (13), the outer wall of the tank (1) has a through hole, the inner wall of the through hole is fixedly connected to an air inlet pipe (11), one end of the air inlet pipe (11) is fixedly connected to the outer wall of the vertical pipe (9), and the inside of the tank (1) is provided with a mixing mechanism.
2. The mixing reaction apparatus according to claim 1, characterized in that, The mixing mechanism includes a hollow piston (14), and one-way valves (12) are fixedly installed on the outer walls of the air inlet pipe (11) and the fixed pipe (10). The bottom of the fixed pipe (10) is fixedly connected to the top of the piston (14).
3. The mixing reaction apparatus according to claim 1, characterized in that, The top of the tank (1) is fixedly connected to the injection pipe (2).
4. The mixing reaction apparatus according to claim 1, characterized in that, The bottom of the tank (1) is provided with a through hole, and the inner wall of the through hole is rotatably connected to the outer wall of the output shaft of the motor (4).
5. A mixing reaction apparatus according to claim 1, characterized in that, The vertical pipe (9) and the top of the tank (1) are provided with the same through hole, and the inner wall of the through hole is slidably connected to the outer wall of the output end of the electric push rod (8).
6. A mixing reaction apparatus according to claim 2, characterized in that, The outer wall of the piston (14) is slidably connected to the inner wall of the vertical tube (9).
7. A mixing reaction apparatus according to claim 1, characterized in that, The outer wall of the tank (1) is fixedly fitted with a shell sleeve (15), and multiple electric heating plates are fixedly connected inside the shell sleeve (15).