Automatic surface enhanced Raman spectrum detector

Abstract

The utility model discloses an automatic surface enhanced Raman spectrum detector which comprises a box body, a box cover hinged to one side of the box body, and a sample detection bin, a Raman placement bin and a plurality of liquid adding grooves which are formed in the top of the box body, a sample disc is arranged on the inner side of the sample detection bin, a sample groove is formed in the top of the sample disc, a plurality of clamping grooves are formed in the inner side of the sample groove, and a plurality of detection holes are formed in the side face of the sample disc. The sample disc, the Raman module, the liquid separator and the box body form an integrated structure, so that automatic surface enhanced Raman spectrum detection can be realized, a to-be-detected liquid, a nano reagent and a coagulant can be accurately added and mixed, the volume of the added liquid and the reaction time can be accurately controlled through software, the detection efficiency is improved, and the detection cost is reduced. The consistency of the detection processes of different batches is ensured, the interference caused by manual operation is effectively avoided, the cross contamination of reagents is prevented, the consistency of experimental conditions is improved, and the accuracy of quantitative detection is ensured.

Description

Technical Field

[0001] This utility model relates to the field of Raman spectrometer technology, and in particular to an automatic surface-enhanced Raman spectrometer. Background Technology

[0002] Surface-enhanced Raman spectroscopy (SERS) has become an important tool in the field of trace substance detection since its inception due to its high sensitivity and unique molecular "fingerprinting" capabilities. This technology enhances the Raman signal intensity by 5 to 7 orders of magnitude by adsorbing analyte molecules onto the surface of metal nanostructures (such as gold and silver nanoparticles) or embedding them into their rough interfaces, utilizing the localized surface plasmon resonance effect. This overcomes the bottleneck of insufficient sensitivity in traditional Raman spectroscopy. In recent years, SERS has shown broad application prospects in food safety, biomedicine, and environmental monitoring, especially in the rapid screening of trace pollutants such as illegal additives, pesticide residues, and pathogens, thanks to its advantages of rapid response, non-destructive testing, and quantitative analysis.

[0003] Using a colloidal substrate is the most direct way to obtain Raman enhanced signals. Typically, a chemical reduction wet process is used to prepare metal (gold, silver) nanoparticles to obtain the colloidal substrate. The intensity of the SERS signal is affected not only by the material itself but also by the time interval during the operation. This is especially true for quantitative operations, where the time between adding the coagulant and acquiring the signal is a significant influencing factor.

[0004] Chinese utility model patent CN222497314U discloses a portable Raman spectrometer. By placing the Raman spectrometer inside a portable case, it is easy to carry the Raman spectrometer. Furthermore, by using a probe lifting frame, the detection probe is inserted into the probe hole, thereby making the detection probe vertically aligned with the sample on the sample stage surface for vertical detection.

[0005] In practice, the three substances—the nano-reinforced substrate, the test solution, and the coagulant—generally need to be mixed. This portable Raman spectrometer requires manual operation for pipetting, mixing, and detection. This manual operation is not only inefficient but also poses a risk of cross-contamination. For example, when adding reagents manually, operator errors such as insufficient pipetting precision or delays can lead to variations in mixing time, affecting the aggregation state of the metal nanoparticles and the adsorption uniformity of the analyte molecules, ultimately causing signal fluctuations or quantitative deviations. These problems are particularly prominent in scenarios requiring high-throughput or repeatable testing, such as screening large batches of samples in food safety testing, where inconsistencies in operation often lead to decreased reliability of test results. Summary of the Invention

[0006] This invention overcomes the shortcomings of the prior art and provides an automatic surface-enhanced Raman spectroscopy detector.

[0007] To achieve the above objectives, the technical solution adopted by this utility model is as follows: an automatic surface-enhanced Raman spectroscopy detector, comprising: a housing, a housing cover hinged to one side of the housing, and a sample detection chamber, a Raman placement chamber, and several liquid addition tanks opened on the top of the housing;

[0008] The sample detection chamber has a sample tray on its inner side, a sample slot on its top, and several slots for placing test bottles containing the liquid to be tested on its inner side. The sample tray has several detection holes on its side that extend to the inner side of the slots. The inner side of the housing is equipped with a power source for precisely driving the sample tray to rotate.

[0009] The inner side of the Raman placement chamber is fitted with a Raman module for rapid detection of the analyte; the inner side of several liquid addition tanks is fitted with several dispensing devices for automatically adding nano-reagents and coagulants to the detection bottles respectively; the inner side of the box is equipped with a controller for receiving and sending control commands to realize automatic surface-enhanced Raman spectroscopy.

[0010] In a preferred embodiment of this utility model, the number of slots and detection holes are the same, and they are evenly distributed in a circular array; the probe of the Raman module faces the detection hole and is coaxially arranged; the controller is electrically connected to the power source, the Raman module and the dispenser respectively.

[0011] In a preferred embodiment of this utility model, a photoelectric switch for determining whether a detection bottle exists in the slot is installed on the inner side of the housing. The sensor end of the photoelectric switch faces the detection hole and is coaxially arranged. The photoelectric switch is electrically connected to the controller.

[0012] In a preferred embodiment of this utility model, the power source includes: a servo motor fixed inside the housing, and a foolproof locking block fixed to the output end of the servo motor; the bottom of the sample tray is engaged with the side of the foolproof locking block.

[0013] In a preferred embodiment of this utility model, the dispenser includes: a reagent bottle snapped into the inside of the liquid filling tank, a dispenser cap threaded to the top of the reagent bottle, and a dispenser tube fixed to the side of the dispenser cap; a power chamber is provided on the inner side of the dispenser cap, and a micro peristaltic pump is installed on the inner side of the power chamber, the input end of the micro peristaltic pump is connected to the inside of the reagent bottle, and the output end is connected to the inside of the dispenser tube.

[0014] In a preferred embodiment of this invention, one end of the dispensing tube faces the top of the slot, and is used to achieve quantitative dispensing of reagents through the top of the detection bottle.

[0015] In a preferred embodiment of this utility model, a display screen for displaying the currently set detection parameters is installed on one side of the box cover, and the display screen is electrically connected to the controller.

[0016] In a preferred embodiment of this utility model, a power switch and a detection switch are provided on the top of the housing, and the power switch and the detection switch are electrically connected to the controller respectively.

[0017] In a preferred embodiment of this utility model, the top of the Raman placement chamber is provided with several handle slots for facilitating the placement and removal of the Raman module.

[0018] In a preferred embodiment of this utility model, a handle is fixed on one side of the box body, and a connection hole is provided on one side of both the box body and the box cover. The connection hole is used to close and protect the box body and the box cover through a connector.

[0019] This utility model solves the defects existing in the background technology, and has the following beneficial effects:

[0020] (1) This utility model provides an automatic surface-enhanced Raman spectroscopy detector. By integrating the sample plate, Raman module, and liquid dispenser with the housing, multiple test bottles containing the test liquid are placed inside several slots on the top of the sample plate. Through the cooperation of the controller, sample plate, power source, liquid dispenser and Raman module, automatic surface-enhanced Raman spectroscopy detection can be achieved. This not only allows for the precise addition and mixing of the test liquid, nano-reagent and coagulant, but also allows for precise control of the volume of added liquid and reaction time through software, thereby improving detection efficiency, ensuring consistency of detection processes for different batches, effectively avoiding interference caused by manual operation, preventing cross-contamination of reagents, improving the consistency of experimental conditions, and ensuring the accuracy of quantitative detection.

[0021] (2) In this utility model, by installing a photoelectric switch on the inside of the box, after the test bottle is placed inside the slot, the photoelectric switch can use optical principle to perform non-contact detection on the slot in the detection hole at the sensor end, determine the serial number of the test bottle, so that when the reagent is dispensed to the test bottle, the corresponding slot can be controlled to be moved to the dispensing position, thereby avoiding the occurrence of test bottle gaps in the slot, which would cause liquid spillage during dispensing, and improving detection efficiency and automation control level.

[0022] (3) In this utility model, by attaching the dispenser to the inside of the liquid addition tank, since one end of the dispenser tube is facing the top of the slot, when the slot containing the test bottle is moved to the bottom of one end of the dispenser tube, the reagent can be accurately added to the test bottle through the cooperation of the reagent bottle, dispenser cap, micro peristaltic pump and dispenser tube, thus avoiding errors in manual operation and cross-contamination of reagents. Attached Figure Description

[0023] The present invention will be further described below with reference to the accompanying drawings and embodiments;

[0024] Figure 1 This is a perspective structural diagram of a preferred embodiment of the present invention;

[0025] Figure 2 This is a structural diagram showing the separation of the sample tray, Raman module, and dispenser from the housing in a preferred embodiment of this utility model.

[0026] Figure 3 This is a front half-sectional view of the box body according to a preferred embodiment of the present invention;

[0027] Figure 4 This is a side half-sectional view of the box body according to a preferred embodiment of the present invention;

[0028] Figure 5 This is a structural diagram of the connection between the anti-foolproof card block and the sample tray in a preferred embodiment of this utility model;

[0029] Figure 6 This is a half-sectional view of the connection between the dispensing cap and the reagent bottle in a preferred embodiment of this utility model.

[0030] In the diagram: 1. Box body; 11. Box lid; 12. Sample detection chamber; 13. Raman placement chamber; 14. Liquid addition tank; 2. Sample tray; 21. Sample slot; 22. Slot; 23. Detection hole; 211. Servo motor; 212. Fooled-proof block; 3. Raman module; 4. Dispenser; 41. Reagent bottle; 42. Dispensing cap; 43. Dispensing tube; 44. Power chamber; 45. Miniature peristaltic pump; 5. Controller; 6. Photoelectric switch; 7. Display screen; 8. Power switch; 81. Detection switch; 9. Handle slot; 10. Handle; 101. Connection hole. Detailed Implementation

[0031] The present invention will now be described in further detail with reference to the accompanying drawings and embodiments. These drawings are simplified schematic diagrams, which are only used to illustrate the basic structure of the present invention in a schematic manner, and therefore only show the components related to the present invention.

[0032] like Figure 1-3As shown, an automatic surface-enhanced Raman spectroscopy detector includes: a housing 1, a cover 11 hinged to one side of the housing 1, and a sample detection chamber 12, a Raman placement chamber 13, and several liquid addition tanks 14 located on the top of the housing 1; a sample tray 2 is provided inside the sample detection chamber 12, a sample groove 21 is provided on the top of the sample tray 2, several slots 22 for placing test bottles containing test liquids are provided inside the sample grooves 21, and several detection holes 23 are provided on the side of the sample tray 2, extending to the inside of the slots 22; a power source for precisely driving the sample tray 2 to rotate is installed inside the housing 1; a Raman module 3 for rapid detection of the test substance is attached to the inside of the Raman placement chamber 13; several dispensing devices 4 for automatically adding nano-reagents and coagulants to the test bottles are attached to the inside of the several liquid addition tanks 14; and a controller 5 for receiving and transmitting control commands to realize automatic surface-enhanced Raman spectroscopy is provided inside the housing 1.

[0033] It should be noted that the number of slots 22 and detection holes 23 are the same, and they are evenly distributed in a circular array; the probe of the Raman module 3 faces the detection hole 23 and is coaxially arranged; the controller 5 is electrically connected to the power source, the Raman module 3, and the dispenser 4 respectively; the communication power supply of the Raman module 3 is connected to the data terminal through a plastic-coated steel pipe to reduce fiber optic bending damage. Using a snap-fit ​​installation method, the Raman module 3 can be removed for detection of constant compounds or connected to other automated pretreatment equipment for online detection. The laser wavelength of the Raman module 3 is 785nm, the laser power is 0-500mW, and the Raman spectral range is 200-3100cm². -1 The spectral resolution is ≤6cm. -1 The displacement accuracy is ≤5cm -1 Displacement repeatability is ≤1cm -1 .

[0034] Specifically, multiple test bottles containing 100 μL of the test solution are placed in several slots 22 on the top of the sample tray 2. The power source is controlled by the controller 5 to drive the sample tray 2 to rotate and pick up the test bottles. Several dispensing devices 4 are controlled to add 300 μL of nano-reagent (55 nm diameter gold nanoparticles) and 100 μL of coagulant (sodium chloride aqueous solution) to the multiple test bottles in sequence. The power source is controlled again to drive the sample tray 2 to quickly rotate forward and backward to mix the test solution. Then, the test bottles are picked up in sequence so that the detection holes 23 on the side of the sample tray 2 are aligned with the probe of the Raman module 3. This allows for SERS detection of the test substance in the test bottle with the detection hole 23. Through automated control, not only can the test solution, nano-reagent, and coagulant be accurately added and mixed, but the volume of the added liquid and the reaction time can also be precisely controlled by the software. This improves the detection efficiency, ensures the consistency of the detection process for different batches, effectively avoids interference caused by manual operation, prevents cross-contamination of reagents, improves the consistency of experimental conditions, and ensures the accuracy of quantitative detection.

[0035] It is understood that the control method and control circuit of controller 5 can be implemented by those skilled in the art through simple programming, and are common knowledge in the field. Furthermore, since this application is mainly used to protect mechanical devices, the control method and circuit connection will not be explained in detail here.

[0036] like Figure 4 As shown, in some embodiments, a photoelectric switch 6 is installed on the inner side of the housing 1 to determine whether a detection bottle exists in the card slot 22. The sensor end of the photoelectric switch 6 faces the detection hole 23 and is coaxially arranged; the photoelectric switch 6 is electrically connected to the controller 5.

[0037] It should be noted that the detection distance of photoelectric switch 6 is 2-30mm, the photoelectric size is 7mm, the operating voltage is 12-24V DC, and the output current is below 50mA.

[0038] Specifically, after the test bottle is placed inside the slot 22, the controller 5 controls the power source to drive the sample tray 2 to rotate one revolution. The photoelectric switch 6 uses optical principles to perform non-contact detection on the slot 22 inside the detection hole 23 at the sensor end. When the test bottle is inside the slot 22, it will block the light emitted by the photoelectric switch 6, thereby triggering the switch action. After receiving the signal from the photoelectric switch 6, the controller 5 records the position of the slot 22 where the test bottle is located. When dispensing reagents to the test bottle, it can control the corresponding slot 22 to be retrieved to the dispensing position, thereby avoiding the occurrence of empty test bottles in the slot 22, which would cause liquid spillage during dispensing, thus improving detection efficiency and automation control level.

[0039] like Figure 5As shown, in some embodiments, the power source includes: a servo motor 211 fixed inside the housing 1, and a foolproof locking block 212 fixed at the output end of the servo motor 211; the bottom of the sample tray 2 is engaged with the side of the foolproof locking block 212.

[0040] Specifically, the sample tray 2 can be disassembled by the snap-fit ​​mechanism between the bottom of the sample tray 2 and the anti-foolproof clip 212, facilitating the placement and cleaning of the test bottles. After placing the test bottle inside the slot 22 on the sample tray 2, the bottom of the sample tray 2 can be directly snapped into the side of the anti-foolproof clip 212 for installation. The servo motor 211, which can precisely control the speed and position, can drive the sample tray 2 to rotate, enabling precise positioning and sequential testing of the test bottles. Simultaneously, the control of rapid forward and reverse rotation can uniformly mix the test liquid and reagents inside the test bottle, improving testing efficiency.

[0041] like Figure 6 As shown, in some embodiments, the dispenser 4 includes: a reagent bottle 41 snapped into the inside of the liquid filling tank 14, a dispenser cap 42 threaded to the top of the reagent bottle 41, and a dispenser tube 43 fixed to the side of the dispenser cap 42; a power chamber 44 is provided on the inside of the dispenser cap 42, and a micro peristaltic pump 45 is installed on the inside of the power chamber 44. The input end of the micro peristaltic pump 45 is connected to the inside of the reagent bottle 41, and the output end is connected to the inside of the dispenser tube 43.

[0042] It should be noted that one end of the dispensing tube 43 faces the top of the slot 22, and is used to achieve quantitative dispensing of reagents through the top of the test bottle; the technical parameters of the micro peristaltic pump 45 are: power supply DC3.7V, power 1-2W, outlet pressure ≤0.03MPa; the pipelines at the input and output ends of the micro peristaltic pump 45 and the dispensing tube 43 are all corrosion-resistant flexible tubes, with technical parameters of temperature resistance from -50℃ to 135℃, and possessing acid and alkali resistance and oxidation resistance.

[0043] Specifically, when the slot 22 containing the test liquid is positioned at the bottom of one end of the dispensing tube 43, the controller 5 controls the micro peristaltic pump 45 to start. Through its internal peristaltic motion, the reagent is drawn out from the reagent bottle 41 and output through the dispensing tube 43, allowing the reagent to be accurately added to the test bottle. This avoids errors and contamination caused by manual operation. At the same time, the snap-fit ​​structure of the dispenser 4 makes it easy to install and disassemble, facilitating maintenance and replacement.

[0044] like Figure 1 and Figure 2 As shown, in some embodiments, a display screen 7 for displaying the currently set detection parameters is installed on one side of the cover 11. The display screen 7 is electrically connected to the controller 5. The display screen 7 allows the user to intuitively view the currently set detection parameters, making it easy to adjust and confirm them.

[0045] In a possible design, controller 5 also includes a Bluetooth module. This module uses a Nordic nRF52840 Bluetooth Low Energy (BLE) chip as its core, integrating an ARM Cortex-M4 processor, a 2.4GHz RF transceiver, and a built-in antenna matching network, with a package size of 6mm × 6mm QFN. Through the Bluetooth module settings, users can send parameters for reagent dispensing (such as target volume, flow rate mode, or number of dispensings) to controller 5 in real time via a custom-developed app, while simultaneously receiving device status feedback. After parsing the app commands, controller 5 dynamically adjusts the motor drive signal of the micro-peristaltic pump 45 and synchronously updates the operation information on the display screen 7, forming a closed-loop control logic of "mobile terminal setting—device terminal execution—data feedback verification." This allows users to complete operations in special environments such as sterile workbenches and biosafety cabinets without direct contact with the dispenser 4, reducing the risk of contamination. Furthermore, operation data can be automatically recorded and exported as electronic reports for easy traceability of the experimental process.

[0046] In some embodiments, a power switch 8 and a detection switch 81 are provided on the top of the housing 1. The power switch 8 and the detection switch 81 are electrically connected to the controller 5 respectively. The power switch 8 and the detection switch 81 provide basic control functions for the detector, enabling users to easily turn on the power and start the detection process, thereby improving the ease of use and operability of the detector.

[0047] In some embodiments, the top of the Raman placement chamber 13 is provided with several handle slots 9 for easy placement and removal of the Raman module 3; the handle slots 9 make it easy to install and remove the Raman module 3, and facilitate maintenance and replacement.

[0048] In some embodiments, a handle 10 is fixed to one side of the housing 1, and a connection hole 101 is provided on one side of both the housing 1 and the cover 11. The connection hole 101 is used to close and protect the housing 1 and the cover 11 through a connector. The handle 10 provides portability support for the detector, allowing users to easily carry and move the detector. The connection hole 101 facilitates the tight closure and protection of the housing 1 and the cover 11 through connectors (such as bolts and nuts), avoiding interference and damage to the internal components of the detector from external factors.

[0049] In use, the sample tray 2 is placed in the slot 22 at the top of the sample tray 2, and the sample tray 2 is secured to the side of the anti-foolproof block 212. The servo motor 211 is activated by the controller 5 to drive the sample tray 2 to rotate. When the photoelectric switch 6 detects that the sample tray 2 is in the slot 22 and blocks the light emitted by it, the switch is triggered, and the controller 5 records the slot 22 number where the sample tray 2 is located. Subsequently, the controller 5 activates the micro-peristaltic pump 45 in the dispenser 4 to add 300 μL of nano-reagent (55 nm diameter gold nanoparticles) and 100 μL of coagulant (sodium chloride aqueous solution) to the corresponding sample trays through the dispenser tube 43. Afterward, the controller 5 drives the sample tray 2 to rotate rapidly in both directions to ensure thorough mixing of the sample tray 2 and the reagent. After uniform mixing, the controller 5 sequentially retrieves the sample tray 2, aligning the detection hole 23 on the side of the sample tray 2 with the probe of the Raman module 3 to perform SERS detection on the sample, ensuring high sensitivity and accuracy of the detection. During the testing process, all operations are automated by controller 5, including the precise addition and mixing of reagents, accurate positioning of test vials, and sequential testing. This effectively avoids errors and contamination caused by manual operation, improves testing efficiency and consistency of experimental conditions, and ensures the accuracy of quantitative testing. Simultaneously, users can view the currently set testing parameters on display screen 7 and achieve remote control and data recording via Bluetooth module, further enhancing the ease of use and traceability of the instrument.

[0050] Based on the above description and the preferred embodiments of this utility model, it will be apparent to those skilled in the art that this utility model is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this utility model. Therefore, the embodiments should be considered exemplary and non-limiting in all respects. The scope of this utility model is defined by the appended claims rather than the foregoing description, and thus all variations falling within the meaning and scope of equivalents of the claims are intended to be included within this utility model. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0051] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. An automatic surface-enhanced Raman spectroscopy detector, characterized in that, include: The box body (1), the box cover (11) hinged to one side of the box body (1), and the sample detection chamber (12), Raman placement chamber (13) and several liquid addition tanks (14) opened on the top of the box body (1); The sample detection chamber (12) is provided with a sample tray (2) on its inner side. The top of the sample tray (2) is provided with a sample groove (21). The inner side of the sample groove (21) is provided with several slots (22) for placing test bottles containing the liquid to be tested. The side of the sample tray (2) is provided with several detection holes (23) that extend to the inner side of the slots (22). The inner side of the housing (1) is provided with a power source for precisely driving the sample tray (2) to rotate. The Raman placement chamber (13) is fitted with a Raman module (3) for rapid detection of the test substance; the inner sides of several liquid addition tanks (14) are fitted with several dispensing devices (4) for automatically adding nano-reagents and coagulants to the test bottle respectively; the inner side of the box (1) is equipped with a controller (5) for receiving and sending control commands to realize automatic surface-enhanced Raman spectroscopy.

2. The automatic surface-enhanced Raman spectroscopy detector according to claim 1, characterized in that: The number of slots (22) and the number of detection holes (23) are the same, and they are evenly distributed in a circular array. The probe of the Raman module (3) faces the detection hole (23) and is coaxially arranged. The controller (5) is electrically connected to the power source, the Raman module (3) and the liquid dispenser (4) respectively.

3. An automatic surface-enhanced Raman spectroscopy detector according to claim 1, characterized in that: The inner side of the housing (1) is equipped with a photoelectric switch (6) for determining whether a detection bottle exists in the card slot (22). The sensor end of the photoelectric switch (6) faces the detection hole (23) and is coaxially arranged. The photoelectric switch (6) is electrically connected to the controller (5).

4. An automatic surface-enhanced Raman spectrometer according to claim 1, characterized in that: The power source includes: a servo motor (211) fixed inside the housing (1) and a foolproof locking block (212) fixed at the output end of the servo motor (211); the bottom of the sample tray (2) is engaged with the side of the foolproof locking block (212).

5. An automatic surface-enhanced Raman spectroscopy detector according to claim 1, characterized in that: The dispenser (4) includes: a reagent bottle (41) snapped into the inside of the liquid filling tank (14), a dispenser cap (42) threaded to the top of the reagent bottle (41), and a dispenser tube (43) fixed to the side of the dispenser cap (42); a power chamber (44) is provided on the inside of the dispenser cap (42), and a micro peristaltic pump (45) is installed on the inside of the power chamber (44). The input end of the micro peristaltic pump (45) is connected to the inside of the reagent bottle (41), and the output end is connected to the inside of the dispenser tube (43).

6. An automatic surface-enhanced Raman spectroscopy detector according to claim 5, characterized in that: One end of the dispensing tube (43) faces the top of the slot (22) and is used to quantitatively dispense the reagent through the top of the detection bottle.

7. An automatic surface-enhanced Raman spectroscopy detector according to claim 1, characterized in that: A display screen (7) for displaying the currently set detection parameters is installed on one side of the box cover (11), and the display screen (7) is electrically connected to the controller (5).

8. An automatic surface-enhanced Raman spectroscopy detector according to claim 1, characterized in that: The top of the housing (1) is provided with a power switch (8) and a detection switch (81), which are electrically connected to the controller (5).

9. An automatic surface-enhanced Raman spectrometer according to claim 1, characterized in that: The top of the Raman placement chamber (13) is provided with several handle slots (9) for easy access to the Raman module (3).

10. An automatic surface-enhanced Raman spectroscopy detector according to claim 1, characterized in that: A handle (10) is fixed on one side of the box (1), and a connection hole (101) is provided on one side of both the box (1) and the box cover (11). The connection hole (101) is used to close and protect the box (1) and the box cover (11) through a connector.

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