Carrier anti-deviation and ultrasonic anti-blocking device for magnetic particle chemiluminescence immunoassay analyzer

Abstract

The utility model discloses a carrier anti-deviation and ultrasonic anti-blocking device for a magnetic particle chemiluminescence immunoassay analyzer. The carrier anti-deviation and ultrasonic anti-blocking device comprises a sample bin, a multi-stage electric telescopic rod, a carrier disc, an elastic guide assembly, a sample tube placing frame and a movable adjusting frame group, a mounting groove hole is formed in the inner bottom wall of the sample bin, a multi-stage electric telescopic rod is fixed in the mounting groove hole, the upper end of the mounting groove hole abuts against a carrier plate, a rail rod is fixed on the carrier plate, and elastic guide assemblies are mounted on two sides and two sides in the carrier plate. The sample tube placing rack is connected to the carrier plate in a sliding manner through an elastic guide assembly, and an ultrasonic device is arranged on the movable adjusting rack group. The design of the elastic guide assembly and the V-shaped guide plate prevents the sample tube rack from deviating, and ensures that the tube rack accurately enters a sample bin. The sample tube placing frame adopts a pressing type taking mechanism, and through an elastic supporting structure and a guide device, the sample tube body automatically bounces when being pressed down, so that quick taking operation is realized. In addition, sample liquid or reagents are prevented from being adhered to the inner wall of the probe through the ultrasonic generator and the transducer, and the blocking phenomenon is avoided.

Description

Technical Field

[0001] This utility model relates to the field of chemical analysis instrument technology, and in particular to a device for preventing displacement and ultrasonic anti-blocking of a carrier for a magnetic microparticle chemiluminescence immunoassay analyzer. Background Technology

[0002] The Flash900 fully automated chemiluminescence immunoassay analyzer is a highly automated detection device. Its main components include the main unit, a microcomputer processing system, and other auxiliary components. The main unit encompasses a material preparation module (reaction cup compartment, sample compartment, reagent compartment, etc.), a fluidization module (vacuum pump, tubing, probes, etc.), a temperature control module (incubator, reagent insulator, etc.), a mechanical transmission module (sensors, transport rails, robotic arm, etc.), an optical path detection module (high-sensitivity sensors such as photomultiplier tubes), and a circuit control module (power supply, amplification and processing system, and circuit control board). The microcomputer processing system serves as the instrument's command and control center, possessing functions such as program-controlled operation, automatic monitoring, command interpretation, data processing, and fault diagnosis. Furthermore, it includes a sample processing system (transfer chamber, main probe system), an experimental operating system (fluid system, including rinsing solution, waste liquid, substrate pumps and valves, etc.), a central supply and control system (reaction tube support, reaction tube supply chamber, temperature control zone, and photoelectric reading chamber), and peripheral equipment (color monitor, printer, keyboard, barcode scanner, etc.). These components work together to ensure that the instrument can perform chemiluminescence immunoassay detection tasks efficiently and accurately.

[0003] The chemiluminescence immunoassay analyzers of the aforementioned specifications have defects in practical use. First, the connection between the carrier tray and the sample tube rack in the sample compartment is insufficient. In actual operation, when the operator places the sample rack on the carrier tray, a pusher plate is used to push the sample rack into the sample compartment. Due to the insufficient connection, the sample tube rack may shift during the pushing process, causing the sample rack to fail to enter the sample compartment accurately, affecting detection efficiency and accuracy. This shift not only increases the operator's adjustment time but may also lead to sample rack damage or sample leakage, further affecting the reliability of the detection results.

[0004] Secondly, the sample tube holder in the analyzer also has drawbacks in use. When placing the sample tube into the slot of the holder, the upper end of the sample tube is completely inserted into the slot. After the experiment, the operator needs to push the sample tube upwards through a notch on one side of the holder until the upper end of the sample tube protrudes from the slot opening, and then retrieve the sample tube. This retrieval operation is inconvenient and affects the ease of use of the sample tube holder. In addition, after the probe of the existing technology has absorbed and transferred sample liquid or reagent, there is still sample liquid or reagent liquid remaining inside. When absorbing sample liquid or reagent liquid again, the liquid adhering to the inner wall of the probe can cause the probe to have poor liquid absorption or even blockage. This blockage not only affects the accurate absorption and transfer of sample liquid and reagent, but may also lead to cross-contamination of sample liquid or reagent, reducing the accuracy of detection. Utility Model Content

[0005] The purpose of this invention is to provide a device for preventing displacement of the carrier and an ultrasonic anti-blocking device for a magnetic microparticle chemiluminescence immunoassay analyzer, so as to solve the problems mentioned in the background art.

[0006] To solve the above problems, the technical solution adopted by this utility model is as follows:

[0007] The magnetic particle chemiluminescence immunoassay analyzer carrier anti-displacement and ultrasonic anti-clogging device includes...

[0008] The sample chamber has several mounting slots on its bottom wall, and several multi-stage electric telescopic rods are fixedly installed inside the mounting slots.

[0009] The upper end of the multi-stage electric telescopic rod abuts against a carrier plate, a track rod is fixedly connected to the carrier plate, and elastic guide components are installed on both sides of the track rod and both sides inside the carrier plate.

[0010] A sample tube holder, which is slidably connected to a carrier plate via an elastic guide assembly;

[0011] A movable adjustment frame assembly is provided with a positioning plate on one side. The positioning plate has an installation hole. A probe is fixedly connected inside the installation hole. A sleeve is fixedly installed on the outer wall of the upper end of the probe. An ultrasonic generator is fixedly installed on the positioning plate. An ultrasonic transducer is provided at one end of the ultrasonic generator. The ultrasonic transducer is connected to the outer wall of the sleeve.

[0012] Preferably, the elastic guide assembly includes a fixed seat, a shaft, and a shaft cylinder. Several fixed seats are fixedly connected to both sides of the inner side wall of the carrier plate and both sides of the track rod. One end of the shaft is fixedly connected to one end of the fixed seat. The shaft cylinder is slidably sleeved on the other end of the shaft. A spring is provided between the shaft cylinder and the fixed seat. The spring is sleeved on the outer wall of the shaft.

[0013] Preferably, a V-shaped guide plate is fixedly connected to one end of the shaft cylinder, a plurality of frame plates are fixedly connected to one side wall of the V-shaped guide plate, a support shaft is fixedly connected between two of the frame plates, and a guide wheel is rotatably connected to the outer wall of the support shaft.

[0014] Preferably, the upper wall of the sample tube placement rack has a plurality of sample tube placement holes, and the inner wall of each sample tube placement hole is symmetrically and fixedly connected to two groove rods. A vertical groove is opened on one side wall of each groove rod, and a lifting plate is slidably connected inside the vertical groove. A support plate is fixedly connected to the upper wall of the lifting plate, and the sample tube body is placed on the support plate.

[0015] Preferably, a connecting rod is rotatably connected to one side wall of the sample tube placement rack, a track groove is opened on one side wall of the lifting plate, an adapter rod is movably connected in the track groove, one end of the adapter rod is fixedly connected to one end of the connecting rod, and a second spring is fixedly connected between the bottom wall of the lifting plate and the bottom wall inside the sample tube placement hole.

[0016] Compared with the prior art, this utility model has the following advantages:

[0017] In this invention, the elastic guide assembly effectively prevents the sample holder from shifting during sample placement and pushing, ensuring that the sample holder accurately enters the sample chamber and improving detection efficiency and accuracy. The design of the V-shaped guide plate and guide wheels further enhances the sliding stability and positioning accuracy of the sample holder on the carrier plate, effectively preventing the sample holder from shifting during pushing.

[0018] This invention introduces a unique press-type retrieval mechanism into a sample tube holder. By setting a specific elastic support structure and guiding device inside the holder, when the operator presses down on the sample tube body, the structure can automatically spring the sample tube body upward, so that its upper end protrudes directly out of the slot opening, thereby realizing a quick and convenient retrieval operation.

[0019] This invention, through the use of an ultrasonic generator and an ultrasonic transducer, effectively prevents liquid adhesion to the inner wall of the probe, avoids clogging, ensures accurate sample or reagent aspiration and transfer, and improves the reliability of detection. The ultrasonic waves propagate in the liquid within the probe tube, generating a cavitation effect that breaks down solid particles in the solution, reduces viscosity, and decreases the adhesion of the solution to the inner wall of the tube, allowing the solution to flow smoothly and preventing clogging. Attached Figure Description

[0020] Figure 1 A schematic diagram of the overall structure of the anti-displacement and ultrasonic anti-clogging device for the magnetic particle chemiluminescence immunoassay analyzer carrier.

[0021] Figure 2A schematic diagram of the sample chamber structure of the anti-displacement and ultrasonic anti-clogging device for the magnetic microparticle chemiluminescence immunoassay analyzer carrier.

[0022] Figure 3 A schematic diagram of the carrier tray and sample tube placement rack structure of the anti-displacement and ultrasonic anti-clogging device for the magnetic particle chemiluminescence immunoassay analyzer.

[0023] Figure 4 This is a partial structural diagram of the anti-displacement and ultrasonic anti-clogging device for the magnetic particle chemiluminescence immunoassay analyzer carrier.

[0024] Figure 5 A schematic diagram showing the detailed structure of the sample tube placement rack for the anti-displacement and ultrasonic anti-clogging device of the magnetic particle chemiluminescence immunoassay analyzer.

[0025] Figure 6 A schematic diagram of the disassembled sample tube placement rack of the magnetic particle chemiluminescence immunoassay analyzer carrier anti-displacement and ultrasonic anti-clogging device.

[0026] Figure 7 For the anti-displacement and ultrasonic anti-clogging device of the magnetic particle chemiluminescence immunoassay analyzer carrier. Figure 2 Enlarged view of a portion of point A in the middle;

[0027] Figure 8 For the anti-displacement and ultrasonic anti-clogging device of the magnetic particle chemiluminescence immunoassay analyzer carrier. Figure 3 Enlarged view of a section at point B in the middle;

[0028] Figure 9 For the anti-displacement and ultrasonic anti-clogging device of the magnetic particle chemiluminescence immunoassay analyzer carrier. Figure 4 Enlarged view of a section at point C.

[0029] In the diagram: 1. Sample chamber; 2. Multi-stage electric telescopic rod; 3. Carrier tray; 4. Track rod; 5. Sample tube placement rack; 6. Positioning plate; 7. Probe; 8. Sleeve; 9. Ultrasonic generator; 10. Ultrasonic transducer; 11. Fixing base; 12. Shaft; 13. Shaft cylinder; 14. First spring; 15. V-shaped guide plate; 16. Frame plate; 17. Support shaft; 18. Guide wheel; 19. Sample tube placement hole; 20. Groove rod; 21. Lifting plate; 22. Support plate; 23. Sample tube body; 24. Connecting rod; 25. Track groove; 26. Adaptor rod; 27. Second spring. Detailed Implementation

[0030] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0031] Example:

[0032] Please see Figures 1-9 As shown, this utility model is a device for preventing displacement and ultrasonic blockage of a magnetic particle chemiluminescence immunoassay analyzer carrier, including...

[0033] Sample chamber 1, the bottom wall of the sample chamber 1 is provided with several mounting slots, and several multi-stage electric telescopic rods 2 are fixedly installed inside the mounting slots;

[0034] The upper end of the multi-stage electric telescopic rod 2 abuts against the carrier plate 3, and the carrier plate 3 is fixedly connected to the track rod 4. Elastic guide components are installed on both sides of the track rod 4 and both sides inside the carrier plate 3.

[0035] Sample tube holder 5, which is slidably connected to the carrier plate 3 via an elastic guide assembly;

[0036] A movable adjustment frame assembly is provided with a positioning plate 6 on one side. The positioning plate 6 has an installation hole. A probe 7 is fixedly connected inside the installation hole. A sleeve 8 is fixedly installed on the outer wall of the upper end of the probe 7. An ultrasonic generator 9 is fixedly installed on the positioning plate 6. An ultrasonic transducer 10 is provided at one end of the ultrasonic generator 9. The ultrasonic transducer 10 is connected to the outer wall of the sleeve 8.

[0037] As can be seen from the above, the multi-stage electric telescopic rod 2 is electrically connected to the external controller. In actual use, the multi-stage electric telescopic rod 2 can be driven by the controller to further drive the carrier plate 3 to rise or fall. The operation is convenient and does not require additional manual operation.

[0038] During sample rack placement and pushing, the elastic guiding component effectively prevents sample rack displacement, ensuring accurate entry of the sample rack into sample chamber 1 and improving detection efficiency and accuracy. Simultaneously, the ultrasonic generator 9 and ultrasonic transducer 10 effectively prevent liquid adhesion to the inner wall of probe 7, avoiding blockage and ensuring accurate aspiration and transfer of sample liquid or reagents, thus improving detection reliability.

[0039] Specifically, the ultrasonic generator 9, as the source of ultrasonic waves, provides high-frequency electrical energy to drive the ultrasonic transducer 10. Its sleeve 8 contains a coupling medium to transmit ultrasonic waves from the ultrasonic transducer 10 to the probe 7. The user starts the ultrasonic generator 9 through the operating interface. The ultrasonic waves propagate in the liquid inside the probe 7 needle tube, generating a cavitation effect that breaks down solid particles in the solution, reduces viscosity, and decreases the adhesion of the solution to the inner wall of the needle tube. Through the above effects, the solution inside the needle tube can flow smoothly, avoiding blockage.

[0040] Depend on Figure 2 and Figure 8 It is known that the elastic guide assembly includes a fixed seat 11, a shaft 12 and a shaft cylinder 13. Several fixed seats 11 are fixedly connected to the inner two side walls of the carrier plate 3 and the two side walls of the track rod 4. One end of the shaft 12 is fixedly connected to one end of the fixed seat 11. The shaft cylinder 13 is slidably sleeved on the other end of the shaft 12. A first spring 14 is provided between the shaft cylinder 13 and the fixed seat 11. The first spring 14 is sleeved on the outer wall of the shaft 12.

[0041] A V-shaped guide plate 15 is fixedly connected to one end of the shaft cylinder 13. Several frame plates 16 are fixedly connected to one side wall of the V-shaped guide plate 15. A support shaft 17 is fixedly connected between two frame plates 16. A guide wheel 18 is rotatably connected to the outer wall of the support shaft 17.

[0042] As can be seen from the above, the elastic guide assembly, through the cooperation of the fixed seat 11, shaft 12, shaft cylinder 13 and the first spring 14, realizes the elastic support, limiting and guiding functions of the sample tube placement rack 5. The design of the V-shaped guide plate 15 and the guide wheel 18 further improves the sliding stability and positioning accuracy of the sample tube placement rack 5 on the carrier plate 3, effectively preventing the sample tube rack from shifting during the pushing process and ensuring that the sample rack can accurately enter the sample chamber 1;

[0043] When the sample tube holder 5 is placed on the carrier plate 3, the guide wheel 18 abuts against the side wall of the sample tube holder 5 under the elastic compression of the first spring 14, thereby providing stable support and limiting the sample tube holder 5 to prevent shaking during movement.

[0044] refer to Figure 3 , Figure 5 and Figure 6 As shown, the sample tube placement rack 5 has several sample tube placement holes 19 on its upper wall. The inner wall of each sample tube placement hole 19 is symmetrically connected to two groove rods 20. A vertical groove is opened on one side wall of each groove rod 20. A lifting plate 21 is slidably connected inside the vertical groove. A support plate 22 is fixedly connected to the upper wall of the lifting plate 21. The sample tube body 23 is placed on the support plate 22.

[0045] A connecting rod 24 is rotatably connected to one side wall of the sample tube placement rack 5. A track groove 25 is opened on one side wall of the lifting plate 21. An adapter rod 26 is movably connected in the track groove 25. One end of the adapter rod 26 is fixedly connected to one end of the connecting rod 24. A second spring 27 is fixedly connected between the bottom wall of the lifting plate 21 and the bottom wall of the sample tube placement hole 19.

[0046] As can be seen from the above, during use, the personnel place the sample tube body 23 containing the sample on the support plate 22 and press the sample tube body 23 further. At this time, the second spring 27 is compressed, the connecting rod 24 rotates, and the adapter rod 26 moves inside the track slot 25. The adapter rod 26 moves from the lowest point to the highest point of the track slot 25 and is limited. The sample tube body 23 is then placed into the sample tube placement hole 19. After the experiment is completed, the personnel press the sample tube body 23 down again, which further expands the second spring 27. The adapter rod 26 moves from the highest point to the lowest point of the track slot 25, thus causing the sample tube body 23 to rise, making it easier for the personnel to take the sample tube body 23 out later.

[0047] Compared to the existing technology where the sample tube body 23 inside the sample tube holder 5 is taken out, the present invention, by setting the above structure, eliminates the need to push the sample tube upward through the notch on one side of the holder until the upper end of the sample tube protrudes from the slot opening in order to take out the sample tube. It can be taken out by pressing, which improves the efficiency of personnel taking out the sample tube body 23 and the structural design is more user-friendly.

[0048] All standard parts used in this invention can be purchased from the market, and irregularly shaped parts can be customized according to the description and drawings. The specific connection methods for each part all employ conventional methods such as bolts, rivets, and welding, which are mature technologies in the prior art. The machinery, parts, and equipment all use conventional models in the prior art, and the circuit connections also use conventional connection methods in the prior art, which will not be detailed here. Any content not described in detail in this specification belongs to the prior art known to those skilled in the art.

[0049] In the description of this utility model, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. "A plurality of" means two or more, unless otherwise explicitly specified.

[0050] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0051] In this utility model, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0052] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0053] The accompanying drawings of the embodiments disclosed in this utility model only involve the structures involved in the embodiments disclosed in this utility model. Other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of this utility model can be combined with each other.

[0054] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A device for preventing displacement and ultrasonic blockage of a carrier for a magnetic particle chemiluminescence immunoassay analyzer, characterized in that: include The sample chamber (1) has several mounting slots on its inner bottom wall, and several multi-stage electric telescopic rods (2) are fixedly installed inside the mounting slots. The upper end of the multi-stage electric telescopic rod (2) abuts against the carrier plate (3), and a track rod (4) is fixedly connected to the carrier plate (3). Elastic guide components are installed on both sides of the track rod (4) and both sides inside the carrier plate (3). Sample tube holder (5), which is slidably connected to the carrier plate (3) via an elastic guide assembly; A movable adjustment frame assembly is provided with a positioning plate (6) on one side. The positioning plate (6) has an installation hole. A probe (7) is fixedly connected inside the installation hole. A sleeve (8) is fixedly installed on the outer wall of the upper end of the probe (7). An ultrasonic generator (9) is fixedly installed on the positioning plate (6). An ultrasonic transducer (10) is provided at one end of the ultrasonic generator (9). The ultrasonic transducer (10) is connected to the outer wall of the sleeve (8).

2. The anti-displacement and ultrasonic anti-blocking device for the magnetic particle chemiluminescence immunoassay analyzer carrier according to claim 1, characterized in that: The elastic guide assembly includes a fixed seat (11), a shaft (12), and a shaft cylinder (13). Several fixed seats (11) are fixedly connected to the inner two side walls of the carrier plate (3) and the two side walls of the track rod (4). One end of the shaft (12) is fixedly connected to one end of the fixed seat (11). The shaft cylinder (13) is slidably sleeved on the other end of the shaft (12). A first spring (14) is provided between the shaft cylinder (13) and the fixed seat (11). The first spring (14) is sleeved on the outer wall of the shaft (12).

3. The anti-displacement and ultrasonic anti-blocking device for the magnetic particle chemiluminescence immunoassay analyzer carrier according to claim 2, characterized in that: A V-shaped guide plate (15) is fixedly connected to one end of the shaft cylinder (13). Several frame plates (16) are fixedly connected to one side wall of the V-shaped guide plate (15). A support shaft (17) is fixedly connected between two frame plates (16). A guide wheel (18) is rotatably connected to the outer wall of the support shaft (17).

4. The anti-displacement and ultrasonic anti-blocking device for the magnetic particle chemiluminescence immunoassay analyzer carrier according to claim 1, characterized in that: The sample tube holder (5) has several sample tube placement holes (19) on its upper wall. The inner wall of each sample tube placement hole (19) is symmetrically connected to two groove rods (20). One side wall of each groove rod (20) has a vertical groove. A lifting plate (21) is slidably connected inside the vertical groove. A support plate (22) is fixedly connected to the upper wall of the lifting plate (21). The sample tube body (23) is placed on the support plate (22).

5. The anti-displacement and ultrasonic anti-blocking device for the magnetic particle chemiluminescence immunoassay analyzer carrier according to claim 4, characterized in that: A connecting rod (24) is rotatably connected to one side wall of the sample tube placement rack (5). A track slot (25) is opened on one side wall of the lifting plate (21). An adapter rod (26) is movably connected in the track slot (25). One end of the adapter rod (26) is fixedly connected to one end of the connecting rod (24). A second spring (27) is fixedly connected between the bottom wall of the lifting plate (21) and the bottom wall of the sample tube placement hole (19).

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