A new microfluidic homogenizer device

Abstract

The utility model discloses a novel micro -jet homogenizer equipment, specifically relates to ultrahigh pressure micro -jet homogenizer technical field, including mould temperature machine, high pressure mechanism and cooling assembly, the side of mould temperature machine is provided with high pressure mechanism, and the side away from high pressure mechanism of mould temperature machine is provided with cooling assembly, its through to the outer cabin of high pressure cabin in high pressure mechanism adds high temperature oil and makes the material of initial pressurization to accelerate destruction or decomposition under high temperature environment, and the closed oil tank of high pressure mechanism passes through many oil circuit designs, and the oil circuit that the oil of convenient and fast inflow in high pressure cabin can heat up fast, and the pipeline that the high pressure pump of high pressure mechanism enters the closed oil tank adopts spiral pipeline design, so that high pressure cabin oil circuit heats up fast.

Description

Technical Field

[0001] This utility model relates to the field of ultra-high pressure micro-jet homogenizer technology, and more specifically, to a novel micro-jet homogenizer device. Background Technology

[0002] With the widespread application of nanomaterials in medicine, food, chemical industry and other fields, the requirements for material homogenization are becoming increasingly stringent. Traditional homogenization technology is difficult to meet the needs of nanoscale dispersion. Traditional homogenization technology is energy-intensive and inefficient. In contrast, microjet homogenizers achieve efficient homogenization through high-pressure jets, which significantly reduces energy consumption. Microjet homogenizers can achieve linear scale-up from small-scale to pilot-scale and then to production, ensuring the stability and repeatability of the process and providing reliable technical support for industrial production. However, traditional microjet homogenizers are complex in structure, large in size and occupy a lot of space, which is not conducive to use in laboratory or small production environments.

[0003] A search revealed that publication number CN119318905A discloses a high-pressure microjet homogenization system and process method, relating to the field of high-pressure homogenization equipment technology. The system includes a pneumatic diaphragm pump, a first plunger pump, a second plunger pump, a diamond interactive cavity, a heat exchanger, and a storage container. These components form a material homogenization pipeline, a CIP cleaning pipeline, and a SIP aseptic heating pipeline via pipes. A liposome extrusion pipeline is connected to the material homogenization pipeline. By using a dual-plunger pump, the flow rate of the high-pressure microjet homogenizer is significantly increased. The liposome extrusion pipeline reduces particle size and sedimentation in the product, thus improving product quality. The inventors discovered the following problems with the existing technology during the development of this invention:

[0004] Existing microjet homogenizers are complex in structure, large in size, and occupy a lot of space, making them unsuitable for use in laboratory or small-scale production environments. Furthermore, some traditional microjet homogenizers use micron-level nozzles, which are prone to clogging when processing high-viscosity or particulate materials, affecting continuous operation and increasing maintenance costs. Additionally, some microjet homogenizers experience significant pressure fluctuations during high-pressure operation, affecting homogenization results and product quality stability. Moreover, most microjet homogenizers suffer from noise issues, with the high-pressure jet and mechanical operation generating considerable noise, impacting the working environment, especially when used in laboratories or enclosed spaces.

[0005] Therefore, a novel microjet homogenizer is proposed to address the above problems. Utility Model Content

[0006] In order to overcome the above-mentioned defects of the prior art, the present invention provides a novel microjet homogenizer to solve the problems mentioned in the background art.

[0007] To achieve the above objectives, the present invention provides the following technical solution: a novel microjet homogenizer, comprising a mold temperature controller, a high-pressure mechanism, and a cooling component, wherein the high-pressure mechanism is provided on the side of the mold temperature controller, and the cooling component is provided on the side of the mold temperature controller away from the high-pressure mechanism.

[0008] Preferably, the high-pressure mechanism includes a sealed oil tank, a high-pressure chamber, a high-pressure pump, and a valve assembly. The valve assembly is provided on the side of the sealed oil tank, the high-pressure chamber is provided on the side of the valve assembly away from the sealed oil tank, and the high-pressure pump is provided on the side of the high-pressure chamber away from the valve assembly.

[0009] Preferably, the enclosed oil tank includes a tank body, a spiral pipe and a first connecting pipe, and the spiral pipe is provided on the upper part of the inner wall of the tank body, and the first connecting pipe is installed on the side of the tank body.

[0010] Preferably, the high-pressure chamber includes an inner chamber, an outer chamber, and monitoring components, with the inner chamber installed above the inner wall of the outer chamber and the monitoring components installed on the inner wall of the inner chamber.

[0011] Preferably, the monitoring component includes a first temperature sensor, a second temperature sensor, and a pressure sensor, wherein the second temperature sensor is disposed on the side of the first temperature sensor, and the pressure sensor is disposed above the second temperature sensor.

[0012] Preferably, the high-pressure pump includes a piston assembly and a cylinder, and the piston assembly is mounted on the inner diameter surface of the cylinder. The piston assembly includes a plug body, a piston guide ring, and a piston end seal ring. The piston guide ring is provided on the outer diameter surface of the plug body, and the piston end seal ring is provided above the piston guide ring.

[0013] Preferably, the valve assembly includes a first pressure relief valve, a second pressure relief valve, and a third pressure relief valve, wherein the second pressure relief valve is disposed on the side of the first pressure relief valve, and the third pressure relief valve is disposed above the second pressure relief valve.

[0014] Preferably, the cooling component includes a cooling plate, a chiller, and a second connecting pipe, with the second connecting pipe installed above the cooling plate and the chiller installed on the side of the second connecting pipe.

[0015] The technical effects and advantages of this utility model are as follows:

[0016] 1. Compared with existing technologies, this new type of microjet homogenizer reduces the size of the equipment through optimized structural design, adopts modular design, facilitates installation and maintenance, and adapts to different scenario requirements.

[0017] 2. Compared with the existing technology, this new type of micro-jet homogenizer equipment accelerates the destruction or decomposition of the initially pressurized material by adding high-temperature oil to the outer chamber of the high-pressure chamber in the high-pressure mechanism. The closed oil tank of the high-pressure mechanism is designed with multiple oil channels to facilitate the rapid heating of the oil flowing into the high-pressure chamber. The pipeline of the high-pressure pump of the high-pressure mechanism entering the closed oil tank adopts a spiral pipeline design to facilitate the rapid heating of the oil in the high-pressure chamber.

[0018] 3. Compared with existing technologies, this new type of micro-jet homogenizer introduces an intelligent control system to monitor and adjust parameters such as pressure and flow rate in real time, ensuring a stable homogenization process and improving product quality.

[0019] 4. Compared with existing technologies, this new type of micro-jet homogenizer reduces operating noise and improves the working environment by optimizing the mechanical structure and adding sound insulation materials. It fixes the high-pressure pump and the overall equipment in a relatively integrated manner through multiple fixation points, distributing the vibration and noise of the high-pressure pump to the overall equipment. At the same time, it optimizes the internal structure of the high-pressure pump. The high-pressure pump uses a piston sealing assembly, piston guide ring, and piston end seal ring to achieve soft fit between parts in the hydraulic oil environment, reducing vibration and noise during operation. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0021] Figure 2 This is a front view cross-sectional structural diagram of the sealed oil tank of this utility model.

[0022] Figure 3 This is a front view cross-sectional structural diagram of the high-pressure chamber of this utility model.

[0023] Figure 4 This is a front view cross-sectional structural diagram of the high-pressure pump of this utility model.

[0024] The attached diagram is labeled as follows: 1. Mold temperature controller; 2. High-pressure mechanism; 3. Cooling component; 4. Sealed oil tank; 5. High-pressure chamber; 6. High-pressure pump; 7. Valve assembly; 8. Box body; 9. Spiral pipe; 10. First connecting pipe; 11. Inner chamber; 12. Outer chamber; 13. Monitoring component; 14. First temperature sensor; 15. Second temperature sensor; 16. Pressure sensor; 17. Piston assembly; 18. Cylinder; 19. Plug; 20. Piston guide ring; 21. Piston end sealing ring; 22. First pressure relief valve; 23. Second pressure relief valve; 24. Third pressure relief valve; 25. Cooling plate; 26. Chiller; 27. Second connecting pipe. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] Example 1

[0027] As attached Figures 1 to 4 The present invention relates to a novel microjet homogenizer, comprising a mold temperature controller 1, a high-pressure mechanism 2, and a cooling component 3. The high-pressure mechanism 2 is located on the side of the mold temperature controller 1, and the cooling component 3 is located on the side of the mold temperature controller 1 away from the high-pressure mechanism 2.

[0028] Specifically: When the process requires a temperature of 150℃, the mold temperature controller 1 heats the oil in its oil tank to 150℃ and pumps the oil into the high-pressure mechanism 2 through its pipeline. Then, the high-temperature oil is injected into the high-pressure mechanism 2 through the pipeline of the sealed oil tank 4. When the internal temperature of the high-pressure mechanism 2 reaches 150℃, the mold temperature controller 1 is turned off, the cover of the high-pressure mechanism 2 is opened, the material is automatically fed into the high-pressure mechanism 2, the high-pressure mechanism 2 is turned off, and the preparation for pressurization is entered. During this process, the sealed oil tank 4 in the mold temperature controller 1 will be heated due to the temperature rise, and the cooling component 3 will cool the oil tank in the mold temperature controller 1 through the condensate circulation.

[0029] Example 2

[0030] Based on Example 1, the solution in Example 1 will be further described in detail below with reference to the specific working method, such as... Figures 1 to 4 As shown in the following detailed description: In a preferred embodiment, the high-pressure mechanism 2 includes a sealed oil tank 4, a high-pressure chamber 5, a high-pressure pump 6, and a valve assembly 7. The valve assembly 7 is disposed on the side of the sealed oil tank 4. The high-pressure chamber 5 is disposed on the side of the valve assembly 7 away from the sealed oil tank 4. The high-pressure pump 6 is disposed on the side of the high-pressure chamber 5 away from the valve assembly 7. When the mold temperature controller 1 heats the oil in its oil tank to 150°C, it pumps the oil into the sealed oil tank 4 of the high-pressure mechanism 2 through a pipeline. Then, the sealed oil tank 4 injects the high-temperature oil into the high-pressure chamber 5 to heat the high-pressure chamber 5. When the temperature inside and outside the high-pressure chamber 5 reaches 150°C, the valve assembly 7 automatically closes. At this time, the high-pressure pump 6 starts working and injects high-pressure oil into the sealed oil tank 4. When the oil is heated to 150°C, it injects high-pressure oil into the high-pressure chamber 5.

[0031] In a preferred embodiment, the sealed oil tank 4 includes a tank body 8, a spiral pipe 9, and a first connecting pipe 10. The spiral pipe 9 is provided on the upper part of the inner wall of the tank body 8, and the first connecting pipe 10 is installed on the side of the tank body 8. When the high-pressure pump 6 starts to work, it injects high-pressure oil into the spiral pipe 9 in the sealed oil tank 4 through the first connecting pipe 10, heats the oil to 150°C, and then injects the high-pressure oil into the high-pressure chamber 5.

[0032] In a preferred embodiment, the high-pressure chamber 5 includes an inner chamber 11, an outer chamber 12, and a monitoring component 13. The inner chamber 11 is installed above the inner wall of the outer chamber 12, and the monitoring component 13 is installed on the inner wall of the inner chamber 11. Oil is pumped into a sealed oil tank 4, and then high-temperature oil is injected into the outer chamber 12 of the high-pressure chamber 5 through the sealed oil tank 4. When the monitoring component 13 in the outer chamber 12 senses that the temperature reaches 150°C, the oil injection stops; at the same time, high-temperature oil is injected into the inner chamber 11 of the high-pressure chamber 5.

[0033] In a preferred embodiment, the monitoring component 13 includes a first temperature sensor 14, a second temperature sensor 15, and a pressure sensor 16. The second temperature sensor 15 is disposed on the side of the first temperature sensor 14, and the pressure sensor 16 is disposed above the second temperature sensor 15. Both the second temperature sensor 15 and the first temperature sensor 14 are Pt100 elements. When the temperature changes, the resistance value of the Pt100 element changes accordingly, thereby converting the temperature signal into an electrical signal. The pressure sensor 16 is model MS5611-01. During operation of BA03, when the external air pressure changes, the sensitive element of the high-linearity pressure sensor 16 will deform accordingly. This deformation will change the magnitude of the sensor's electrical signal. The ultra-low power 24-bit Σ analog-to-digital converter will convert the electrical signal output by the pressure sensor 16 into a precise 24-bit digital signal. When the temperature sensed by the first temperature sensor 14 on the inner wall of the outer cabin 12 reaches 150°C, oil injection will stop, and high-temperature oil will be injected into the inner cabin 11. At this time, the first pressure relief valve 22 and the second pressure relief valve 23 need to be opened simultaneously. When the temperature sensed by the temperature sensor installed on the side wall of the inner cabin 11 reaches 150°C, oil injection into the inner cabin 11 needs to be stopped, and the first pressure relief valve 22 and the second pressure relief valve 23 need to be closed. When the high-pressure pump 6 pressurizes the high-pressure chamber 5, the high-pressure pump 6 will stop working when the pressure sensed by the pressure sensor 16 in the high-pressure chamber 5 reaches 400 MPa.

[0034] In a preferred embodiment, the high-pressure pump 6 includes a piston assembly 17 and a cylinder 18. The piston assembly 17 is mounted on the inner diameter surface of the cylinder 18. The piston assembly 17 includes a plug 19, a piston guide ring 20, and a piston end seal ring 21. The piston guide ring 20 is provided on the outer diameter surface of the plug 19, and the piston end seal ring 21 is provided above the piston guide ring 20. When the high-pressure pump 6 processes oil under high pressure, the plug 19 reciprocates within the cylinder 18 under the action of the drive device, thereby realizing the intake and discharge of liquid. The piston guide ring 20 is mounted on the plug 19 and fits tightly against the inner wall of the cylinder 18, guiding the plug 19 to move smoothly along the axial direction of the cylinder 18, preventing the plug 19 from deviating or swaying during movement, and ensuring movement accuracy and stability. The seal ring is installed in key parts such as between the plug 19 and the cylinder 18. When the plug 19 moves, it can effectively prevent liquid from leaking from the gap between the plug 19 and the cylinder 18, ensuring the sealing and pressure build-up of the high-pressure pump 6.

[0035] In a preferred embodiment, the valve assembly 7 includes a first pressure relief valve 22, a second pressure relief valve 23, and a third pressure relief valve 24. The second pressure relief valve 23 is disposed on the side of the first pressure relief valve 22, and the third pressure relief valve 24 is disposed above the second pressure relief valve 23. When high-temperature oil is injected into the high-pressure chamber 5, the first pressure relief valve 22 and the second pressure relief valve 23 are opened. When the second temperature sensor 15 in the high-pressure chamber 5 senses that the temperature reaches 150°C, the oil injection is stopped, and the first pressure relief valve 22 and the second pressure relief valve 23 are closed. After the pressure holding time is completed, the third pressure relief valve 24 is opened, and step-wise pressure relief is performed to depressurize the high-pressure chamber 5. The oil in the high-pressure chamber 5 flows back to the oil tank in the mold temperature controller 1.

[0036] In a preferred embodiment, the cooling component 3 includes a cooling plate 25, a chiller 26, and a second connecting pipe 27. The second connecting pipe 27 is installed above the cooling plate 25, and the chiller 26 is installed on the side of the second connecting pipe 27. When the system needs to cool down the temperature in the oil tank of the mold temperature controller 1, the system will automatically turn on the cooling system and use the chiller 26 to supply cooling water to the cooling plate 25 through the second connecting pipe 27 to cool down the temperature in the oil tank until it is lower than the set temperature of the oil in the oil tank of the mold temperature controller 1.

[0037] The working process of this utility model is as follows: First, if the process requires a temperature of 150℃, the mold temperature controller 1 heats the oil in its oil tank to 150℃ and pumps the oil into the sealed oil tank 4 through a pipeline. Then, the high-temperature oil is injected into the outer chamber 12 of the high-pressure chamber 5 through the sealed oil tank 4. When the first temperature sensor 14 installed on the outer wall of the outer chamber 12 senses that the temperature reaches 150℃, the injection of oil into the outer chamber 12 is stopped, and at the same time, the high-temperature oil is injected into the inner chamber 11 of the high-pressure chamber 5. At this time, the first pressure relief valve 22 and the second pressure relief valve 23 open simultaneously. When the second temperature sensor 15 on the side wall of the inner chamber 11 senses that the temperature reaches 150℃, the injection of oil into the inner chamber 11 is stopped. Simultaneously, the first pressure relief valve 22, the second pressure relief valve 23, and the mold temperature controller 1 are closed, and the cover of the high-pressure chamber 5 is opened. Automatic feeding is initiated, placing the material into the inner chamber 11, and the high-pressure chamber 5 is then closed. At this point, the mold temperature controller 1 and the high-pressure pump 6 need to be started. When the high-pressure pump 6 processes the oil under high pressure, the plug 19, under the action of the drive device, reciprocates within the cylinder 18, thereby achieving the intake and discharge of the liquid. The piston guide ring 20 is installed on the plug 19, and it fits tightly against the inner wall of the cylinder 18, guiding the plug 19 to move smoothly along the axis of the cylinder 18, preventing the plug 19 from shifting or swaying during movement, ensuring movement accuracy and stability. The sealing ring is installed in key areas such as between the plug body 19 and the cylinder body 18. When the plug body 19 moves, it effectively prevents liquid leakage from the gap between the plug body 19 and the cylinder body 18, ensuring the sealing and pressure build-up of the high-pressure pump 6. High-pressure oil is then injected through the first connecting pipe 10 into the spiral pipe 9 in the sealed oil tank 4. This oil is heated to 150°C and injected into the high-pressure chamber 5. Pressure is continuously increased until the pressure sensor 16 in the high-pressure chamber 5 senses a pressure of 400 MPa. At this point, the high-pressure pump 6 stops working and maintains pressure. After the pressure maintenance time is completed, the third pressure relief valve 24 opens and performs step-by-step pressure relief. When the pressure drops below 10 MPa, the valve closes. The mold temperature controller 1 is closed, and the high-pressure chamber 5 is opened to automatically discharge the pressurized material. The oil in the high-pressure chamber 5 is returned to the oil tank in the mold temperature controller 1, while the remaining oil is returned to the pressure relief tank. After the high-temperature oil discharged from the high-pressure chamber 5 flows into the pressure relief tank, due to the high oil temperature, a chiller 26 is used to supply cooling water to the cooling plate 25 through the second connecting pipe 27 to cool down the temperature in the oil tank until the oil temperature is below 25°C. When cooling the oil tank in the mold temperature controller 1, the system will automatically activate the cooling system, using the chiller 26 and the cooling plate 25 to cool down the temperature in the oil tank until it is below the set temperature of the oil in the mold temperature controller 1.

[0038] When the oil level in the low-temperature oil tank is low, the system will automatically activate the first diaphragm pump to pump the oil from the pressure relief tank into the low-temperature oil tank. When the oil level in the mold temperature controller 1 oil tank is low or the low-temperature oil tank reaches a high oil level, the system will automatically activate the second diaphragm pump to pump the oil from the low-temperature oil tank into the mold temperature controller 1 oil tank. The above describes the working principle of this new type of micro-jet homogenizer.

Claims

1. A novel microjet homogenizer, comprising a mold temperature controller (1), a high-pressure mechanism (2), and a cooling assembly (3), characterized in that: The mold temperature controller (1) is provided with a high pressure mechanism (2) on its side, and a cooling component (3) is provided on the side of the mold temperature controller (1) away from the high pressure mechanism (2).

2. The novel microjet homogenizer according to claim 1, characterized in that: The high-pressure mechanism (2) includes a sealed oil tank (4), a high-pressure chamber (5), a high-pressure pump (6), and a valve assembly (7). The valve assembly (7) is provided on the side of the sealed oil tank (4), and the high-pressure chamber (5) is provided on the side of the valve assembly (7) away from the sealed oil tank (4). The high-pressure pump (6) is provided on the side of the high-pressure chamber (5) away from the valve assembly (7).

3. The novel microjet homogenizer according to claim 2, characterized in that: The enclosed oil tank (4) includes a tank body (8), a spiral pipe (9) and a first connecting pipe (10), and the spiral pipe (9) is provided on the upper part of the inner wall of the tank body (8), and the first connecting pipe (10) is installed on the side of the tank body (8).

4. A novel microjet homogenizer according to claim 2, characterized in that: The high-pressure chamber (5) includes an inner chamber (11), an outer chamber (12) and a monitoring component (13), and the inner chamber (11) is installed above the inner wall of the outer chamber (12), and the monitoring component (13) is installed on the inner wall of the inner chamber (11).

5. A novel microjet homogenizer according to claim 4, characterized in that: The monitoring component (13) includes a first temperature sensor (14), a second temperature sensor (15) and a pressure sensor (16), and the second temperature sensor (15) is disposed on the side of the first temperature sensor (14), and the pressure sensor (16) is disposed above the second temperature sensor (15).

6. A novel microfluidic homogenizer according to claim 2, characterized in that: The high-pressure pump (6) includes a piston assembly (17) and a cylinder (18), and the piston assembly (17) is mounted on the inner diameter surface of the cylinder (18). The piston assembly (17) includes a plug body (19), a piston guide ring (20) and a piston end seal ring (21). The piston guide ring (20) is provided on the outer diameter surface of the plug body (19), and the piston end seal ring (21) is provided above the piston guide ring (20).

7. A novel microfluidic homogenizer according to claim 2, characterized in that: The valve assembly (7) includes a first pressure relief valve (22), a second pressure relief valve (23) and a third pressure relief valve (24), and the second pressure relief valve (23) is provided on the side of the first pressure relief valve (22), and the third pressure relief valve (24) is provided above the second pressure relief valve (23).

8. A novel microjet homogenizer according to claim 1, characterized in that: The cooling component (3) includes a cooling plate (25), a chiller (26), and a second connecting pipe (27). The second connecting pipe (27) is installed above the cooling plate (25), and the chiller (26) is installed on the side of the second connecting pipe (27).

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