Evaporator for distillation of R-(+) tetrahydrofurfuryl acid

Abstract

This utility model relates to the field of evaporation equipment technology, specifically to an evaporation device for the distillation process of R-(+)tetrahydrofuran carboxylic acid. The device includes an inner wall of an evaporation sleeve, an evaporation sleeve jacket, a discharge assembly, an upper end cap, a stirring shaft, a stirring shaft mounting assembly, a stirring blade assembly, a feed pipe, a feed sleeve flange, a dispersion disc, a discharge pipe, a thermometer sleeve, a sight glass, a condenser assembly, and a receiving vessel assembly. The feed pipe controls the amount of material entering the distillation device via a valve. After the material is fed into the inner wall of the evaporation sleeve, it is evenly dispersed by the dispersion disc. Utilizing the motor, stirring shaft, and stirring blade assembly, the material forms a film on the inner wall of the evaporation sleeve during the stirring process. The rapidly vaporized material is condensed in the condenser and then received in the receiving vessel, thus improving the distillation effect and preventing localized overheating of the material, which could lead to quality problems.

Description

Technical Field

[0001] This utility model relates to the field of evaporation technology, and in particular to an evaporation apparatus for the distillation process of R-(+)tetrahydrofuran carboxylic acid. Background Technology

[0002] R-(+)tetrahydrofuranic acid is an important pharmaceutical intermediate that can be used to prepare zosin drugs such as alfuzosin and terazosin for treating hypertension, drugs for treating prostate cancer, as well as intermediates for synthesizing cephalosporin antibiotics and chiral adjuvants (R)-acetyltetrahydrofuran.

[0003] In the preparation of R-(+)tetrahydrofuranic acid, rapid evaporation is required during distillation to avoid high temperatures and prolonged evaporation times, which would lead to increased byproducts. Currently, the single-distillation still apparatus used in the preparation of R-(+)tetrahydrofuranic acid suffers from long distillation times and high temperatures, which in turn leads to increased byproducts during the distillation process.

[0004] Therefore, a redistillation apparatus for R-(+) tetrahydrofuran carboxylic acid is proposed to address the shortcomings of existing technologies. Utility Model Content

[0005] The purpose of this invention is to provide an evaporation device for the distillation process of R-(+)tetrahydrofuran carboxylic acid, which solves the problems of local overheating of materials and excessively long distillation time in the prior art, leading to an increase in by-products.

[0006] To achieve the above objectives, this utility model provides an evaporation apparatus for the distillation process of R-(+)tetrahydrofuran carboxylic acid, comprising an inner wall of an evaporation sleeve, an evaporation sleeve jacket, a discharge assembly, an upper end cap, a stirring shaft, a stirring shaft mounting assembly, a stirring blade assembly, a feed pipe, a feed sleeve flange, a dispersion disc, a discharge pipe, a thermometer sleeve, a sight glass, a condenser assembly, and a receiving vessel assembly. The evaporation sleeve jacket is fitted onto the outer side of the inner wall of the evaporation sleeve. The discharge assembly is installed at the lower end of the inner wall of the evaporation sleeve, and the upper end cap is installed at the upper end of the inner wall of the evaporation sleeve. The stirring shaft is mounted via the stirring shaft mounting assembly. The upper end cap extends into the inner wall of the evaporation sleeve. The stirring shaft mounting assembly is installed on the top outer side of the upper end cap. The stirring scraper assembly is installed on the stirring shaft. The feed pipe is installed on one side of the upper end cap. The feed sleeve flange is installed on the feed pipe. The dispersion disc is located below the feed pipe. The discharge pipe is located on the other side of the upper end cap. The thermometer sleeve is installed on the side of the upper end cap near the discharge pipe. The sight glass is installed on the top outer side of the upper end cap. The condenser assembly is connected to the discharge pipe. The receiving vessel assembly is connected to the condenser assembly.

[0007] The discharge assembly includes a discharge head, an inner cylinder clamp for the discharge head, and a loose flange. The discharge head is located at the lower end of the inner wall of the evaporation sleeve. The inner cylinder clamp for the discharge head connects the discharge head and the inner wall of the evaporation sleeve. The loose flange is located at the lower end of the discharge head.

[0008] The stirring shaft mounting assembly includes an elastic washer, a dry-grind mechanical seal, and a reducer frame. The elastic washer is disposed between the upper end cap and the reducer frame. The dry-grind mechanical seal is sleeved on the stirring shaft. The reducer frame is disposed at the upper end of the upper end cap.

[0009] The stirring scraper assembly includes a PTFE blade, a swivel rod, an anti-reverse rod, a PTFE scraper, and a lower block for fixing the blade. The PTFE blade is fixedly mounted on the stirring shaft. The swivel rod is positioned between two of the PTFE blades. The anti-reverse rod is connected to the swivel rod. The PTFE scraper is mounted on the swivel rod. The lower block for fixing the blade is located below the PTFE scraper.

[0010] The condenser assembly includes a condenser inlet, a condenser jacket outlet, a condenser jacket inlet, and a condenser outlet. The condenser inlet is located at the top of the condenser and is connected to the outlet pipe via a pipeline. The condenser jacket outlet is located at the upper end of one side of the condenser. The condenser jacket inlet is located at the lower end of the other side of the condenser. The condenser outlet is located at the bottom of the condenser.

[0011] The receiving vessel assembly includes a receiving vessel inlet, a receiving vessel jacket outlet, a receiving vessel jacket inlet, and a receiving vessel outlet. The receiving vessel inlet is located at the top of the receiving vessel and is connected to the condenser outlet via a pipe. The receiving vessel jacket outlet is located on one side of the upper end of the receiving vessel. The receiving vessel jacket inlet is located on one side of the bottom of the receiving vessel. The receiving vessel outlet is located at the center of the bottom of the receiving vessel.

[0012] The evaporation apparatus for the R-(+) tetrahydrofuran carboxylic acid distillation process further includes an ear-type support and an electrostatic grounding plate. The ear-type support is installed on the outer wall of the evaporation sleeve jacket; the electrostatic grounding plate is installed on the ear-type support and connected to the evaporation sleeve jacket.

[0013] This invention relates to an evaporation apparatus for the distillation process of R-(+)tetrahydrofuran carboxylic acid. The feed pipe controls the amount of material entering the distillation apparatus via a valve. After the material is fed into the inner wall of the evaporation sleeve, it is evenly dispersed by the dispersion disc. Utilizing the cooperation of a motor, the stirring shaft, and the stirring scraper assembly, the material forms a film on the inner wall of the evaporation sleeve during the stirring process. The rapidly vaporized material is then condensed in the condenser and received in the receiving vessel, thereby improving the distillation effect and avoiding localized overheating of the material, which could lead to quality problems. Attached Figure Description

[0014] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be briefly introduced below.

[0015] Figure 1 This is a schematic diagram of the evaporation device for the distillation process of R-(+)tetrahydrofuran carboxylic acid according to this utility model.

[0016] Figure 2 This is a partial top view schematic diagram of the evaporation device for the R-(+)tetrahydrofuran carboxylic acid distillation process of this utility model.

[0017] In the diagram: 1-Discharge head, 2-Inner cylinder clamp of head, 3-Stirring rod, 4-Evaporation sleeve jacket, 5-Inner wall of evaporation sleeve, 6-Ear support, 7-Electrostatic grounding plate, 8-Dispersion disc, 9-Upper head, 10-Feed pipe, 11-Feed sleeve flange, 12-Elastic gasket, 13-Dry grinding mechanical seal, 14-Reducer frame, 15-Thermometer sleeve, 16-Discharge pipe, 17-PTFE blade, 18-Ruyi rod, 19-Anti-reverse rod, 20-PTFE scraper, 21-Lower blade fixing block, 22-Loose flange, 23-Sight glass, 24-Condenser inlet, 25-Condenser jacket outlet, 26-Condenser jacket inlet, 27-Condenser outlet, 28-Receiving vessel inlet, 29-Receiving vessel jacket outlet, 30-Receiving vessel jacket inlet, 31-Receiving vessel outlet. Detailed Implementation

[0018] The embodiments of the present invention are described in detail below. Examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain the present invention, but should not be construed as limiting the present invention.

[0019] Please see Figure 1 and Figure 2 ,in Figure 1 This is a schematic diagram of the evaporation apparatus for the R-(+)tetrahydrofuran carboxylic acid distillation process of this utility model. Figure 2 This is a partial top view schematic diagram of the evaporation device for the R-(+)tetrahydrofuran carboxylic acid distillation process of this utility model.

[0020] This utility model discloses an evaporation device for the distillation process of R-(+)tetrahydrofuran carboxylic acid, comprising an inner wall 5 of an evaporation sleeve, an evaporation sleeve jacket 4, a discharge assembly, an upper end cap 9, a stirring shaft 3, a stirring shaft 3 mounting assembly, a stirring scraper assembly, a feed pipe 10, a feed sleeve flange 11, a dispersion disc 8, a discharge pipe 16, a thermometer sleeve 15, a sight glass 23, a condenser assembly, and a receiving vessel assembly. The discharge assembly includes a discharge end cap 1, an inner end cap clamp 2, and a loose flange 22. The stirring shaft 3 mounting assembly includes an elastic gasket 12, a dry-grind mechanical seal 13, and... The reducer frame 14 includes a stirring and scraping assembly comprising a PTFE blade 17, a ruyi rod 18, an anti-reverse rod 19, a PTFE scraper 20, and a blade fixing block 21. The condenser assembly includes a condenser inlet 24, a condenser jacket outlet 25, a condenser jacket inlet 26, and a condenser outlet 27. The receiving vessel assembly includes a receiving vessel inlet 28, a receiving vessel jacket outlet 29, a receiving vessel jacket inlet 30, and a receiving vessel outlet 31. The evaporation device for the R-(+) tetrahydrofuran carboxylic acid distillation process also includes an ear-type support 6 and an electrostatic grounding plate 7. The aforementioned solution solves the problems of localized overheating of materials and excessively long distillation times, leading to increased by-products in existing technologies. It is understood that the aforementioned solution can improve distillation efficiency and avoid localized overheating of materials, thus preventing quality problems.

[0021] In this embodiment, the evaporator jacket 4 is sleeved on the outer side of the inner wall 5 of the evaporator sleeve. The discharge assembly is installed at the lower end of the inner wall 5 of the evaporator sleeve. The upper end cap 9 is installed at the upper end of the inner wall 5 of the evaporator sleeve. The stirring shaft 3 is installed on the upper end cap 9 through the stirring shaft 3 mounting assembly and extends into the inner wall 5 of the evaporator sleeve. The stirring shaft 3 mounting assembly is installed on the top outer side of the upper end cap 9. The stirring scraper assembly is installed on the stirring shaft 3. The feed pipe 10 is installed on one side of the upper end cap 9. The feed sleeve flange 11 is installed on the feed pipe 10. The dispersion disk 8 is located below the feed pipe 10. The discharge pipe 16 is located on the other side of the upper end cap 9. The thermometer sleeve 15 is installed on the side of the upper end cap 9 near the discharge pipe 16. The sight glass 23 is installed on the top outer side of the upper end cap 9. The condenser assembly is connected to the discharge pipe 16. The receiving vessel assembly is connected to the condenser assembly. The evaporator jacket 4 is fitted around the outer side of the inner wall 5 of the evaporator jacket. The discharge assembly is installed at the lower end of the inner wall 5 of the evaporator jacket, and the upper end cap 9 is installed at the upper end of the inner wall 5 of the evaporator jacket, forming the main evaporator housing space for material distillation. The upper inlet of the feed pipe 10 is fitted with the feed sleeve flange 11 for feeding. The feed flow rate of the feed pipe 10 is controlled by a valve. The lower outlet of the feed pipe 10 is connected to the dispersion disc 8. After the material is fed into the evaporator through the feed pipe 10, it is evenly distributed into the inner wall 5 of the evaporator jacket by the dispersion disc 8 to avoid local accumulation. The stirring shaft 3 is mounted through the stirring shaft 3 mounting assembly. A motor is connected to the top of the stirring shaft 3 mounting assembly, which drives the stirring shaft 3 to rotate. The rotation of the stirring shaft 3 drives the stirring scraper assembly mounted on it to rotate, which is used to stir the material and spread the material on the inner wall of the evaporator jacket through the stirring scraper assembly. 5. A film is formed to promote rapid vaporization of the material. The vaporized material is transported to the condenser through the discharge pipe 16. Cooling medium is introduced into the cooler through the condenser assembly to condense the vaporized material. Then, the condensed material is input into the receiving vessel assembly, and the temperature of the material is controlled. Finally, the material is output from the bottom of the receiving vessel. The thermometer sleeve 15 is used to install a monitoring thermometer for easy monitoring of the distillation temperature. The sight glass 23 on the upper end cap 9 is used to see through the material distillation inside the evaporator. Therefore, in the distillation device, the feed pipe 10 controls the amount of material entering the distillation device through the valve. After the material is input into the inner wall 5 of the evaporation sleeve, it is evenly dispersed by the dispersion plate 8. With the cooperation of the motor, the stirring shaft 3 and the stirring scraper assembly, the material forms a film on the inner wall 5 of the evaporation sleeve during the stirring process. The rapidly vaporized material is condensed in the condenser and received in the receiving vessel, thereby improving the distillation effect and avoiding local overheating of the material and quality problems.

[0022] The discharge end cap 1 is located at the lower end of the inner wall 5 of the evaporation sleeve; the inner cylinder clamp 2 connects the discharge end cap 1 and the inner wall 5 of the evaporation sleeve; and the loose flange 22 is located at the lower end of the discharge end cap 1. The discharge end cap 1 is used to receive the material after the main distillation reaction, providing a transition material for downward discharge. The discharge end cap 1 is securely connected to the inner wall 5 of the evaporation sleeve by the inner cylinder clamp 2 to prevent leakage. The discharge end cap 1 is connected to an external pipeline through the loose flange 22 to discharge the material from the evaporator into subsequent processing stages. The discharge assembly can be flexibly disassembled and the discharge pipeline can be adjusted to adapt to different production scenarios.

[0023] Secondly, the elastic washer 12 is disposed between the upper end cap 9 and the reducer frame 14; the dry grinding mechanical seal 13 is sleeved on the stirring shaft 3; and the reducer frame 14 is disposed at the upper end of the upper end cap 9. The installation of the elastic washer 12 serves as a buffer, ensuring the stable installation of the reducer frame 14 and the stirring shaft 3. The installation of the dry grinding mechanical seal 13 ensures the sealing effect and prevents material leakage. A motor is installed at the upper end of the reducer frame 14, which drives the stirring shaft 3 to rotate. The reducer frame 14 provides power transmission and deceleration for the rotation of the stirring shaft 3, ensuring the uniform rotation and buffered stop of the stirring shaft 3.

[0024] Meanwhile, the PTFE impeller 17 is fixedly mounted on the stirring shaft 3; the auspicious rod 18 is positioned between the two PTFE impellers 17; the anti-reflection rod 19 is connected to the auspicious rod 18; the PTFE scraper 20 is mounted on the auspicious rod 18; and the lower block 21 of the impeller fixing block is located below the PTFE scraper 20. The auspicious rod 18 and the anti-reflection rod 19 fix the PTFE scraper 20 between the upper and lower PTFE impellers 17, and the installation of the lower block 21 of the impeller fixing block provides support for the PTFE scraper 20, maintaining stirring balance. These multiple stirring scraper assemblies are staggered on the stirring shaft 3. Through the rotation of the stirring shaft 3, the multiple stirring scraper assemblies drive the material to form a film on the inner wall 5 of the evaporation sleeve, thereby accelerating the vaporization rate of the material.

[0025] Then, the condenser inlet 24 is located at the top of the condenser and is connected to the outlet pipe 16 via a pipeline; the condenser jacket outlet 25 is located at the upper end of one side of the condenser; the condenser jacket inlet 26 is located at the lower end of the other side of the condenser; and the condenser outlet 27 is located at the bottom of the condenser. The condenser assembly is installed on the silicon carbide condenser, receiving vaporized material from the evaporator through the condenser inlet 24 at the top of the condenser. Cooling material is input from the condenser jacket inlet 26 and output from the condenser jacket outlet 25. The installation positions of the inlet and outlet ensure the residence time of the cooling material to cool the vaporized material in the condenser. The cooled material is then transported to the receiving vessel via a pipeline through the condenser outlet 27.

[0026] Additionally, the receiving vessel inlet 28 is located at the top of the receiving vessel and is connected to the condenser outlet 27 via a pipe; the receiving vessel jacket outlet 29 is located on one side of the upper end of the receiving vessel; the receiving vessel jacket inlet 30 is located on one side of the bottom of the receiving vessel; and the receiving vessel outlet 31 is located at the center of the bottom of the receiving vessel. The receiving vessel inlet 28 inputs the material cooled by the condenser into the receiving vessel. The receiving vessel jacket inlet 30 and the receiving vessel jacket outlet 29 form a cooling cycle for the receiving vessel. Cooling medium is introduced and circulates in the jacket to maintain the material at a suitable temperature. Then, the material flows out from the receiving vessel outlet 31, completing the distillation process.

[0027] Furthermore, the lug-type support 6 is installed on the outer wall of the evaporator jacket 4; the electrostatic grounding plate 7 is installed on the lug-type support 6 and connected to the evaporator jacket 4. The installation of the lug-type support 6 and the electrostatic grounding plate 7 serves to discharge static electricity from the evaporator, ensuring the safe operation of the device.

[0028] When using the evaporation device for the distillation process of R-(+)tetrahydrofuran carboxylic acid according to this utility model, the feed pipe 10 controls the amount of material entering the distillation device through a valve. After the material is fed into the inner wall 5 of the evaporation sleeve, it is evenly dispersed by the dispersion plate 8. With the cooperation of the motor, the stirring shaft 3 and the stirring scraper assembly, the material forms a film on the inner wall 5 of the evaporation sleeve during the stirring process. The material is rapidly vaporized and then condensed in the condenser and received in the receiving vessel, thereby improving the distillation effect and avoiding local overheating of the material, which could lead to quality problems.

[0029] The above-disclosed embodiments are merely one or more preferred embodiments of this application and should not be construed as limiting the scope of this application. Those skilled in the art can understand that all or part of the processes for implementing the above embodiments and equivalent changes made in accordance with the claims of this application still fall within the scope of this application.

Claims

1. An evaporation apparatus for the distillation process of R-(+)tetrahydrofuran carboxylic acid, characterized in that, The evaporator includes an inner wall of an evaporator jacket, an evaporator jacket jacket, a discharge assembly, an upper end cap, a stirring shaft, a stirring shaft mounting assembly, a stirring blade assembly, a feed pipe, a feed sleeve flange, a dispersion disc, a discharge pipe, a thermometer sleeve, a sight glass, a condenser assembly, and a receiving vessel assembly. The evaporator jacket is fitted onto the outer side of the inner wall of the evaporator jacket. The discharge assembly is installed at the lower end of the inner wall of the evaporator jacket, and the upper end cap is installed at the upper end of the inner wall of the evaporator jacket. The stirring shaft is mounted on the upper end cap via the stirring shaft mounting assembly and extends into the inner wall of the evaporator jacket. The stirring shaft mounting assembly is installed on the outer top of the upper head, the stirring scraper assembly is installed on the stirring shaft, the feed pipe is installed on one side of the upper head, the feed sleeve flange is installed on the feed pipe, the dispersion disc is located below the feed pipe, the discharge pipe is located on the other side of the upper head, the thermometer sleeve is installed on the side of the upper head near the discharge pipe, the sight glass is installed on the outer top of the upper head, the condenser assembly is connected to the discharge pipe, and the receiving vessel assembly is connected to the condenser assembly.

2. The evaporation apparatus for the R-(+)tetrahydrofuran carboxylic acid distillation process as described in claim 1, characterized in that, The discharge assembly includes a discharge head, an inner cylinder clamp for the head, and a loose flange. The discharge head is located at the lower end of the inner wall of the evaporation sleeve. The inner cylinder clamp for the head connects the discharge head and the inner wall of the evaporation sleeve. The loose flange is located at the lower end of the discharge head.

3. The evaporation apparatus for the R-(+)tetrahydrofuran carboxylic acid distillation process as described in claim 1, characterized in that, The stirring shaft mounting assembly includes an elastic washer, a dry-grind mechanical seal, and a reducer frame. The elastic washer is disposed between the upper end cap and the reducer frame. The dry-grind mechanical seal is sleeved on the stirring shaft. The reducer frame is disposed at the upper end of the upper end cap.

4. The evaporation apparatus for the R-(+)tetrahydrofuran carboxylic acid distillation process as described in claim 1, characterized in that, The stirring blade assembly includes a PTFE blade, a control rod, an anti-reverse rod, a PTFE scraper, and a lower blade fixing block. The PTFE blade is fixedly mounted on the stirring shaft. The control rod is positioned between two PTFE blades. The anti-reverse rod is connected to the control rod. The PTFE scraper is mounted on the control rod. The lower blade fixing block is located below the PTFE scraper.

5. The evaporation apparatus for the R-(+)tetrahydrofuran carboxylic acid distillation process as described in claim 1, characterized in that, The condenser assembly includes a condenser inlet, a condenser jacket outlet, a condenser jacket inlet, and a condenser outlet. The condenser inlet is located at the top of the condenser and is connected to the outlet pipe via a pipeline. The condenser jacket outlet is located at the upper end of one side of the condenser. The condenser jacket inlet is located at the lower end of the other side of the condenser. The condenser outlet is located at the bottom of the condenser.

6. The evaporation apparatus for the R-(+)tetrahydrofuran carboxylic acid distillation process as described in claim 5, characterized in that, The receiving vessel assembly includes a receiving vessel inlet, a receiving vessel jacket outlet, a receiving vessel jacket inlet, and a receiving vessel outlet. The receiving vessel inlet is located at the top of the receiving vessel and is connected to the condenser outlet via a pipe. The receiving vessel jacket outlet is located on one side of the upper end of the receiving vessel. The receiving vessel jacket inlet is located on one side of the bottom of the receiving vessel. The receiving vessel outlet is located at the center of the bottom of the receiving vessel.

7. The evaporation apparatus for the R-(+)tetrahydrofuran carboxylic acid distillation process as described in claim 1, characterized in that, The evaporation apparatus for the R-(+) tetrahydrofuran carboxylic acid distillation process further includes an ear-type support and an electrostatic grounding plate. The ear-type support is installed on the outer wall of the evaporation sleeve jacket; the electrostatic grounding plate is installed on the ear-type support and connected to the evaporation sleeve jacket.

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