Process for extracting epigoitrin from isatis root and use thereof

A technology that reports Yichun and Banlangen, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulations, organic active ingredients, etc., can solve the problem of not being able to use large-scale production
CN100341861CInactive Publication Date: 2007-10-10SUZHOU SYLVAN NATURAL PROD R&D CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SUZHOU SYLVAN NATURAL PROD R&D CO LTD
Publication Date
2007-10-10
Estimated Expiration
Not applicable · inactive patent

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Abstract

This invention discloses a method of extracting biao-gao-yi-chun from isatis root. The procedures include (a) ethanol water solution is back flow extracting solution and its weight is 30-95% of 6-12 times isatis root weight, then extracting solutions are combined. (b) Ethanol is recovered after filtration and then liquor is got. (c) The liquor flows through big holes resin adsorption column. (d) Scrubbing column is scrubbed by scrub solution until effluent liquid is leuko. (e) It is eluted by 30-95% weight percentage ethanol water solution, and eluent is collected. (f) The eluent is dried and solid substance is got. (g) Average particle diameter is -0.001-2mm powder is got after grinding. (h) The powder got from (g) is added to alumina column, (i) gradient elution is done by chloroform and ethanol component solvent, every 200-1000ml is one flow portion in order to add 0.1-2ml methanol after collecting every 50 portion. (j) The portions contain biao-gao-yi-chun are collected. (k) Solvent is discharged from the portion in (j), and then biao-gao-yi-chun extract product is got. This invention also provides the use of biao-gao-yi-chun in preparing antivirus medicine.
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Description

technical field

[0001] The invention relates to the field of extraction technology of effective components of traditional Chinese medicines, in particular, it relates to the extraction and preparation of Radix Radix Radix Isatidis Zhongbiaoyichun. The present invention also relates to the new medicinal application of Yichun. Background technique

[0002] Banlangen is a commonly used Chinese herbal medicine, which is the root of Isatis indigotica. It is widely cultivated in China and has the effect of clearing away heat and detoxifying (Zhonghua Materia Medica, pp.2346, 3.709). Existing reports show that it has antiviral (Isatis Radix Chemical Constituents Research (I), Chinese Herbal Medicine, Volume 32, No. 12, 2001, pp1057), antibacterial endotoxin (Herald of Medicine, Volume 21, No.2, pp. 74, 2002), anticancer, antidepressant (Chinese herbal medicine, 2001, Vol. 32, No. 7, pp.670-671). It is also published in literature that the antiviral effect of Radix isatidis is de...

Claims

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