4 results about "Alumina column" patented technology

This invention belongs to the fields of pharmaceutical chemistry and radiomedicine, specifically relating to a ruthenium complex with dual activation capabilities for near-infrared light and X-rays, its preparation method, and its application in antitumor drugs. The complex is characterized by the chemical structural formula [Ru(NO2-tpy)(Pyr-phen)Cl](PF6). The preparation method involves weighing the ligand p-Pyr-phen, the ruthenium precursor Ru(NO2-tpy)Cl3, and lithium chloride LiCl in an ethanol / water mixed solvent, and carrying out a reflux reaction in the presence of triethylamine. After the reaction is complete, the mixture is cooled to room temperature, and then an aqueous solution of ammonium hexafluorophosphate is added. After stirring, a precipitate is formed, collected, and washed sequentially with water and ethanol to remove soluble inorganic salts and polar impurities. The ruthenium complex is obtained after washing and alumina column chromatography. The advantages include a narrower bandgap, stronger near-infrared absorption, and direct X-ray activation capability, enabling dose-dependent generation of singlet oxygen.

The invention discloses a refining method of electronic-grade N-hydroxymethyl acrylamide, which aims to obtain an N-hydroxymethyl acrylamide monomer with low metal impurity content, and comprises the following treatment steps: (1) dissolving N-hydroxymethyl acrylamide in an organic solvent; (2) enabling a solution of N-hydroxymethyl acrylamide to flow through the filled neutral alumina column to adsorb oligomers and part of metal ions; and (4) adding an ethanol / water mixed solution into the viscous liquid obtained after distillation, cooling to separate out a solid, and drying at 40 DEG C to obtain the low-metal N-hydroxymethyl acrylamide monomer, the metal ion is less than 50ppb, the refining yield is about 60%, and the method is simple in process and suitable for industrial production.

The utility model discloses a health environmental protection type outer wall brick relates to outer wall brick field, including wall brick body, the wall brick body top is connected with the anti -aging structure, the surface of alumina column has the transparent ceramic coating that smears, the wall brick body top is seted up with the water -repellent groove, the wall brick body side is provided with the clamping mechanism of improving wall brick practicality, and the clamping mechanism includes the connecting block no. of symmetry connection in the both sides of wall brick body, the connecting block no. bottom is fixed with two insert blocks. This health environmental protection type outer wall brick, when wall brick outer wall receives light, light is through transparent ceramic coating and shines to the mirror surface of the top end of alumina column that is inclined and is not the same in direction, will reflect light, reduces the heat accumulation of wall brick body, and transparent ceramic coating can protect the antifouling and anticorrosive of alumina column, and PTFE spacer is pasted wall brick side, and the wall brick is stably protected by the characteristics such as insulation, corrosion -resistant, non -water absorption, and two water -repellent grooves can be quickly discharged with the inclined plane rainwater, and multiple protection prolongs the life of wall brick, and indirectly improves environmental protection.

The invention provides a preparation process and a decoloration purification method of p-hydroxybiphenyl nitrile for display, and belongs to the technical field of organic synthesis and preparation of liquid crystal material intermediates. Aiming at the defects of high cost, low yield and poor product purity of the existing process, the invention adopts the innovative design of three-step core reaction and four-step decoloration purification: methylsulfonyl chloride is used for replacing benzene sulfonyl chloride to realize hydroxyl low-cost protection, and the isomer content 1t is controlled through four-section gradient heating bromination reaction; and decoloring and purifying by a four-step method of ethanol extraction, activated carbon decoloring, EDTA (Ethylene Diamine Tetraacetic Acid) complexing, alumina column chromatography and DMF (Dimethyl Formamide) / dichloroethane recrystallization. The method has the beneficial effects that the raw material cost is obviously reduced compared with that of a traditional process, and the total molar yield is increased from 48% to 60%; the product purity reaches 99.8%, the chromaticity L value is 92, and the heavy metal residue is 1t; the method overcomes the defects of high cost, low yield, difficulty in decolorization and the like of the traditional process, and the used raw materials and equipment are chemical conventional categories, have definite steps and can be industrially amplified.